Volatile Biomarkers

Volatile Biomarkers
Author: Anton Amann,David Smith
Publsiher: Newnes
Total Pages: 600
Release: 2013-03-27
ISBN 10: 0444626204
ISBN 13: 9780444626202
Language: EN, FR, DE, ES & NL

Volatile Biomarkers Book Review:

Volatile organic compounds (VOCs) in exhaled breath, sweat or urine carry much information on the state of human health. The role of VOCs in clinical diagnosis and therapeutic monitoring is expected to become increasingly significant due to recent advances in the field. Volatile Biomarkers: Non-Invasive Diagnosis in Physiology and Medicine includes the latest discoveries and applications for VOCs from the world's foremost scientists and clinicians working in this emerging analytic area. Appeals to a multidisciplinary audience, including scientists, researchers, and clinicians with an interest in breath analysis Features the latest scientific research and technical breakthroughs in the diagnostic and therapeutic aspects of volatile organic compounds Includes case presentations documenting applications in multiple areas of human health and safety

Breathborne Biomarkers and the Human Volatilome

Breathborne Biomarkers and the Human Volatilome
Author: Jonathan Beauchamp,Cristina Davis,Joachim Pleil
Publsiher: Elsevier
Total Pages: 690
Release: 2020-07-03
ISBN 10: 0128199679
ISBN 13: 9780128199671
Language: EN, FR, DE, ES & NL

Breathborne Biomarkers and the Human Volatilome Book Review:

Breathborne biomarkers carry information on the state of human health, and their role in aiding clinical diagnosis or in therapeutic monitoring has become increasingly important as advances in the field are made. Breathborne Biomarkers and the Human Volatilome, Second Edition, provides a comprehensive update and reworking of the 2013 book Volatile Biomarkers, by Anton Amann and David Smith. The new editing team has expanded this edition beyond volatile organic compounds to cover the broad field of breath analysis, including the many exciting developments that have occurred since the first edition was published. This thoroughly revised volume includes the latest discoveries and applications in breath research from the world's foremost scientists, and offers insights into related future developments. It is an ideal resource for researchers, scientists, and clinicians with an interest in breath analysis. Presents recent advances in the field of breath analysis Includes an extensive overview of established biomarkers, detection tools, disease targets, specific applications, data analytics, and study design Offers a broad treatise of each topic, from basic concepts to a comprehensive review of discoveries, current consensus of understanding, and prospective future developments Acts as both a primer for beginners and a reference for seasoned researchers

Breathborne Biomarkers and the Human Volatilome

Breathborne Biomarkers and the Human Volatilome
Author: Jonathan Beauchamp,Cristina Davis,Joachim Pleil
Publsiher: Elsevier
Total Pages: 722
Release: 2020-06-06
ISBN 10: 0128223979
ISBN 13: 9780128223970
Language: EN, FR, DE, ES & NL

Breathborne Biomarkers and the Human Volatilome Book Review:

Breathborne biomarkers carry information on the state of human health, and their role in aiding clinical diagnosis or in therapeutic monitoring has become increasingly important as advances in the field are made. Breathborne Biomarkers and the Human Volatilome, Second Edition, provides a comprehensive update and reworking of the 2013 book Volatile Biomarkers, by Anton Amann and David Smith. The new editing team has expanded this edition beyond volatile organic compounds to cover the broad field of breath analysis, including the many exciting developments that have occurred since the first edition was published. This thoroughly revised volume includes the latest discoveries and applications in breath research from the world's foremost scientists, and offers insights into related future developments. It is an ideal resource for researchers, scientists, and clinicians with an interest in breath analysis. Presents recent advances in the field of breath analysis Includes an extensive overview of established biomarkers, detection tools, disease targets, specific applications, data analytics, and study design Offers a broad treatise of each topic, from basic concepts to a comprehensive review of discoveries, current consensus of understanding, and prospective future developments Acts as both a primer for beginners and a reference for seasoned researchers

Identification Methods and Chemometric Analysis of Mammalian Volatile Biomarkers

Identification Methods and Chemometric Analysis of Mammalian Volatile Biomarkers
Author: Shamitha Asoka Dissanayake
Publsiher: Unknown
Total Pages: 142
Release: 2014
ISBN 10:
ISBN 13: OCLC:892874296
Language: EN, FR, DE, ES & NL

Identification Methods and Chemometric Analysis of Mammalian Volatile Biomarkers Book Review:

The ultimate goal of this research is to provide a low cost, efficient, reproducible, quantitative, non-invasive screening method to diagnose diseases at an early stage through identification of volatile biomarkers of disease. Progress has been made in the areas towards development of an analytical system that can provide a rapid and specific assay for above mentioned Volatile Organic Compounds (VOCs). (i) Methods have been designed for the collection, concentration, identification and quantification of volatile biomarkers. (ii) Advanced signal processing evaluation of data has tentatively identified key VOCs patterns with breath and body odor. (iii) Novel absorbent coatings have been studied for use with miniature chemical sensors that one day may be part of a portable analytical system. Both breath and body odor contain a complex mixture of chemicals, which are influenced by many internal and external factors. Breath and skin odor samples were collected with minimum external contaminations using traditional SPME and active SPME GCMS techniques. Body odor from 65 human subjects was tested with and without selected scent removal products. Breath samples were collected from 21 canine subjects. The VOCs profiles of these samples were determined and then statistically treated with principal component analysis, discriminant analysis, and tree regression techniques to simplify and interpret the complex mixtures. While much of our work has utilized large bench-top equipment, our over-arching goal is to provide a portable device that can diagnose diseases at an early stage. Concurrent work was done to enhance the performance of a miniaturized detector for the detection of potential biomarkers. Two organic polymers mixed with conductive carbon nanoparticles were deposited between the microcapacitor plates of microsensors using ink-jet technology. Microsensors were also fabricated using conducting ionic liquids. The performances of the individual chemicapacitive sensors were characterized through exposure to different concentrations of varied volatile organic compounds with different functional groups in a climate-controlled vapor delivery system.

Volatile Biomarkers of Blood Glucose

Volatile Biomarkers of Blood Glucose
Author: Bhavin Parekh
Publsiher: Unknown
Total Pages: 329
Release: 2011
ISBN 10:
ISBN 13: OCLC:890150453
Language: EN, FR, DE, ES & NL

Volatile Biomarkers of Blood Glucose Book Review:

Analysis of Volatile Biomarkers from in Vitro Cell Cultures and Exhaled Breath for Ventilator associated Pneumonia Diagnosis

Analysis of Volatile Biomarkers from in Vitro Cell Cultures and Exhaled Breath for Ventilator associated Pneumonia Diagnosis
Author: Oluwasola Lawal
Publsiher: Unknown
Total Pages: 329
Release: 2019
ISBN 10:
ISBN 13: OCLC:1197754727
Language: EN, FR, DE, ES & NL

Analysis of Volatile Biomarkers from in Vitro Cell Cultures and Exhaled Breath for Ventilator associated Pneumonia Diagnosis Book Review:

Use of Gas Analysis Technology to Develop Volatile Biomarkers for Lung Cancer and Explore the Association Between Lung Cancer and Air Pollution

Use of Gas Analysis Technology to Develop Volatile Biomarkers for Lung Cancer and Explore the Association Between Lung Cancer and Air Pollution
Author: 曾千
Publsiher: Unknown
Total Pages: 329
Release: 2019
ISBN 10:
ISBN 13: OCLC:1198970533
Language: EN, FR, DE, ES & NL

Use of Gas Analysis Technology to Develop Volatile Biomarkers for Lung Cancer and Explore the Association Between Lung Cancer and Air Pollution Book Review:

Volatile Biomarkers Emitted by Cell Cultures

Volatile Biomarkers Emitted by Cell Cultures
Author: Thomas W. E. Chippendale
Publsiher: Unknown
Total Pages: 329
Release: 2012
ISBN 10:
ISBN 13: OCLC:1063475405
Language: EN, FR, DE, ES & NL

Volatile Biomarkers Emitted by Cell Cultures Book Review:

Volatile Biomarkers from Cultured Human Immune Cells Cultured Human Acute Lymphoblastic Leukemia Cells and the Exhaled Breath of Patients with Acute Myelolgenous Leukemia

Volatile Biomarkers from Cultured Human Immune Cells  Cultured Human Acute Lymphoblastic Leukemia Cells and the Exhaled Breath of Patients with Acute Myelolgenous Leukemia
Author: Brandon James Umber
Publsiher: Unknown
Total Pages: 168
Release: 2012
ISBN 10: 9781267171078
ISBN 13: 1267171073
Language: EN, FR, DE, ES & NL

Volatile Biomarkers from Cultured Human Immune Cells Cultured Human Acute Lymphoblastic Leukemia Cells and the Exhaled Breath of Patients with Acute Myelolgenous Leukemia Book Review:

Presented here are the volatile organic compounds (VOCs) that were observed to be produced or consumed by healthy and malignant human immune cells as well as those observed in the exhaled breath of patients with acute myelogenous leukemia (AML). Two lineages of white cells were investigated: the lymphoid and the myeloid line of cellular differentiation. The lymphoid lineage was investigated using cultured human peripheral blood mononuclear cells (PBMCs) from healthy donors and cryogenically preserved leukemic cells collected from patients with acute lymphocytic leukemia (ALL). Likewise, the myeloid lineage was investigated using mature neutrophils from healthy donors, the HL60 cell line (malignant immature neutrophils), and the whole air collection of the exhaled breath of patients with AML. Cell cultures were grown in hermetically sealable glass culture flasks and the headspace above the culture was collected for analysis. The exhaled breath of patients with AML and the exhalant of healthy controls were collected in evacuated stainless steel canisters. Analysis of the samples was performed using gas chromatography. Cultured PBMCs were shown to reduce the concentration of acetaldehyde in the headspace relative to controls. Acetaldehyde in the headspace was 1.9±1 ppbv less than what was present in the media. Likewise hexanaldehyde was lower by 0.10±0.05 ppbv. Acute lymphocytic leukemia cells produced greater amounts of acetaldehyde and dimethyl sulfide relative to controls: 14±5 ppbv and 200±50 ppbv above controls. Healthy nuetrophils in culture produced a concentration of acetaldehyde of 4.5±5.4 ppbv above control and had a level of hexanaldehyde 80±60 pptv below controls. The HL60 cells produced 11±3 ppbv of acetaldehyde and 200±70 pptv of hexanladehyde. The exhaled breath of patients with AML contained levels of five VOCs that were significantly different from those found in the healthy controls: acetaldehyde, butane, carbon disulfide, carbonyl sulfide, and heptane. Carbon disulfide and butane were present in levels above the healthy controls and the ambient room concentrations: 15±17 pptv and 700±1,300 pptv. With the goal of diagnostic efficacy in mind it is hoped that the nascent VOC profile of leukemia discussed in this work may provide a foundation for future studies.

The Handbook of Biomarkers

The Handbook of Biomarkers
Author: Kewal K. Jain
Publsiher: Springer Science & Business Media
Total Pages: 492
Release: 2010-02-06
ISBN 10: 9781607616856
ISBN 13: 1607616858
Language: EN, FR, DE, ES & NL

The Handbook of Biomarkers Book Review:

Of the thousands of biomarkers that are currently being discovered, relatively few are being validated for further applications, and the potential of a biomarker can be quite difficult to evaluate. To aid in this imperative research, Dr. Kewal K. Jain’s Handbook of Biomarkers thoroughly describes many different types of biomarkers and their discovery using various "-omics" technologies, such as proteomics and metabolomics, along with the background information needed for the evaluation of biomarkers as well as the essential procedures for their validation and use in clinical trials. With biomarkers described first according to technologies and then according to various diseases, this detailed book features the key correlations between diseases and classifications of biomarkers, which provides the reader with a guide to sort out current and future biomarkers. Comprehensive and cutting-edge, The Handbook of Biomarkers serves as a vital guide to furthering our understanding of biomarkers, which, by facilitating the combination of therapeutics with diagnostics, promise to play an important role in the development of personalized medicine, one of the most important emerging trends in healthcare today.

Analysis of Volatile Biomarkers of Airway Inflammation in Breath

Analysis of Volatile Biomarkers of Airway Inflammation in Breath
Author: Jack F. Dummer
Publsiher: Unknown
Total Pages: 352
Release: 2010
ISBN 10:
ISBN 13: OCLC:774983686
Language: EN, FR, DE, ES & NL

Analysis of Volatile Biomarkers of Airway Inflammation in Breath Book Review:

Biosensing Technologies for the Detection of Pathogens

Biosensing Technologies for the Detection of Pathogens
Author: Toonika Rinken,Kairi Kivirand
Publsiher: BoD – Books on Demand
Total Pages: 216
Release: 2018-03-21
ISBN 10: 9535139150
ISBN 13: 9789535139157
Language: EN, FR, DE, ES & NL

Biosensing Technologies for the Detection of Pathogens Book Review:

Rapid multiplex detection of pathogens in the environment and in our food is a key factor for the prevention and effective treatment of infectious diseases. Biosensing technologies combining the high selectivity of biomolecular recognition and the sensitivity of modern signal detection platforms are a prospective option for automated analyses. They allow rapid detection of single molecules as well as cellular substances. This book, including 12 chapters from 50 authors, introduces the principles of identification of specific pathogen biomarkers along with different biosensor-based technologies applied for pathogen detection.

Biomarkers in Allergy and Asthma An Issue of Immunology and Allergy Clinics of North America E Book

Biomarkers in Allergy and Asthma  An Issue of Immunology and Allergy Clinics of North America E Book
Author: Flavia Hoyte,Rohit K. Katial
Publsiher: Elsevier Health Sciences
Total Pages: 329
Release: 2018-10-23
ISBN 10: 0323641407
ISBN 13: 9780323641401
Language: EN, FR, DE, ES & NL

Biomarkers in Allergy and Asthma An Issue of Immunology and Allergy Clinics of North America E Book Book Review:

This issue of Immunology and Allergy Clinics, guest edited by Drs. Flavia Hoyte and Rohit Katial, is devoted to Biomarkers in Allergy and Asthma. Articles in this issue include: Exhaled Nitric Oxide; Biomarkers in Exhaled Breath Condensate (EBC); Role of Eosinophils in Asthma; Bronchoprovocation Testing in Asthma; Periostin and DPP4; Role of Neutrophils in Asthma; Urinary LTE4; Biomarkers in Nasal Polyps; IgE as a Biomarker in Asthma; Genetics of Asthma; and Biomarker-directed Therapies for Asthma.

Update on Biomarkers in Allergy and Asthma An Issue of Immunology and Allergy Clinics

Update on Biomarkers in Allergy and Asthma  An Issue of Immunology and Allergy Clinics
Author: Rohit Katial
Publsiher: Elsevier Health Sciences
Total Pages: 120
Release: 2012-10-22
ISBN 10: 1455750921
ISBN 13: 9781455750924
Language: EN, FR, DE, ES & NL

Update on Biomarkers in Allergy and Asthma An Issue of Immunology and Allergy Clinics Book Review:

This issue of Immunology and Allergy Clinics provides a comprehensive review of the current state of biomarkers and their role in the asthma diagnostic and therapeutic algorithm.Since the last issue on Biomarkers, which published in 2007, significant research directly targeted at biomarker development and clinical trials with new biologics, using biomarkers such as exhaled nitric oxide, sputum and tissue eosinophilia as endpoints, has occurred.

Recent Advancements in Biomarkers and Early Detection of Gastrointestinal Cancers

Recent Advancements in Biomarkers and Early Detection of Gastrointestinal Cancers
Author: Pallaval Veera Bramhachari,Nageswara Rao Reddy Neelapu
Publsiher: Springer Nature
Total Pages: 231
Release: 2020-07-21
ISBN 10: 981154431X
ISBN 13: 9789811544316
Language: EN, FR, DE, ES & NL

Recent Advancements in Biomarkers and Early Detection of Gastrointestinal Cancers Book Review:

This book describes various novel biomarkers for the early diagnosis of gastrointestinal (GI) cancers. It also highlights recent advances in understanding the role of molecular markers and biomarkers, such as volatile biomarkers, serum biomarkers, predictive and prognostic molecular markers for the early detection of GI cancers. Further, it discusses novel biomarkers, including circulating microRNAs, serum microRNA and plasma microRNA in GI cancer. The book presents breakthrough technologies like ultra-sensitive nano-chips, nanosensors, nanodevices, biosensors, electrochemical biosensors, optical biosensors, DNA biosensors, synthetic biology devices, and 'omics' technologies for the early diagnosis of gastrointestinal cancer. In addition it examines the potential of genome-wide association studies, big data analytics, computation biology, systems biology, and nanotechnology for early diagnostics and therapeutics for gastrointestinal cancer, with a focus on personalized cancer treatment. The book is a valuable source for researchers and clinicians engaged in detection and diagnosis of gastrointestinal cancers.

Volatile Organic Compound Analysis in Biomedical Diagnosis Applications

Volatile Organic Compound Analysis in Biomedical Diagnosis Applications
Author: Raquel Cumeras,Xavier Correig
Publsiher: CRC Press
Total Pages: 272
Release: 2018-11-22
ISBN 10: 042978242X
ISBN 13: 9780429782428
Language: EN, FR, DE, ES & NL

Volatile Organic Compound Analysis in Biomedical Diagnosis Applications Book Review:

This volume presents a thought-provoking state-of-the-art picture of how volatile compounds are used in metabolomics, currently a hot topic in the metabolomics field. It provides a thorough description of what volatile organic compounds (VOCs) are, why they are important in biomedicine, and what the analytical platforms are used. It also looks at multivariate analysis and databases needs. Because VOCs are end-up compounds of metabolic processes, volatiles can be linked to different diseases or pathologies for both diagnosis and prognosis. The authors provide authoritative information and guidance on the analytical and statistical techniques used and how to identify, and they review the main current areas of application, which include breath metabolomics, cancer diagnosis, and microbial volatiles. Key Features: Presents a thorough overview of volatile research in biomedical applications Examines both gold standard techniques (metabolomics based) and artificial olfactory systems Reviews all aspects of volatile metabolites in biomedicine research, from origin to detection platforms Describes relevant diseases diagnosis and prognosis achievements, including cancer

In Vitro Analysis of Volatile Organic Compounds in Search of Potential Biomarkers of Lung Cancer

In Vitro Analysis of Volatile Organic Compounds in Search of Potential Biomarkers of Lung Cancer
Author: K. Schmidt
Publsiher: Unknown
Total Pages: 329
Release: 2016
ISBN 10:
ISBN 13: OCLC:1079208863
Language: EN, FR, DE, ES & NL

In Vitro Analysis of Volatile Organic Compounds in Search of Potential Biomarkers of Lung Cancer Book Review:

Cancer Biomarkers

Cancer Biomarkers
Author: Debmalya Barh,Angelo Carpi,Mukesh Verma,Mehmet Gunduz
Publsiher: CRC Press
Total Pages: 951
Release: 2014-01-30
ISBN 10: 1466584289
ISBN 13: 9781466584280
Language: EN, FR, DE, ES & NL

Cancer Biomarkers Book Review:

Gleaning information from more than 100 experts in the field of cancer diagnosis, prognosis, and therapy worldwide, Cancer Biomarkers: Non-Invasive Early Diagnosis and Prognosis determines the significance of clinical validation approaches for several markers. This book examines the use of noninvasive or minimally invasive molecular cancer markers that are under development or currently in use. It deals with a majority of commonly prevalent cancers and can help anyone working in the health-care industry to recommend or develop early diagnostics, at-risk tests, and prognostic biomarkers for various cancers. It explores the practice of determining biomarkers by their characteristics and relative methodologies, and presents the most recent data as well as a number of current and upcoming early diagnostic noninvasive molecular markers for many common cancers. It also considers the sensitivity and specificity of markers, biomarker market, test providers, and patent information. Approximately 30-35 Cancer Specific Noninvasive Molecular Diagnostic Markers in a Single Volume The book details the general and technical aspects of noninvasive cancer markers. It covers imaging, cutting-edge molecular technologies for biomarker development, and noninvasive or minimally invasive sources of molecular markers, as well as quality control and ethical issues in cancer biomarker discovery. It also provides a detailed account of brain, head and neck, and oral cancer markers, and provides information on a number of gastrointestinal cancers, lung cancer, and mesothelioma markers. Emphasizes the Importance of Volatile Markers in Early Cancer Diagnosis Presents noninvasive early molecular markers in urological cancers Describes gynecological and endocrine cancer markers Details noninvasive markers of breast, ovarian, cervical, and thyroid cancers Addresses hematological malignancies Contains information on noninvasive molecular markers in myelodysplastic syndromes, acute myeloid leukemia, Hodgkin’s lymphoma, and multiple myeloma Provides comprehensive information on diagnostic and prognostic biomarkers in cutaneous melanoma This text considers molecular technologies for biomarker development, noninvasive or minimally invasive sources of molecular markers, and quality control and ethical issues in cancer biomarker discovery.

Diagnostic Potential of Volatile Organic Compounds and Lactoferrin as Biomarkers in Inflammatory Bowel Disease

Diagnostic Potential of Volatile Organic Compounds and Lactoferrin as Biomarkers in Inflammatory Bowel Disease
Author: Demuni Hiruni Jayasena
Publsiher: Unknown
Total Pages: 329
Release: 2013
ISBN 10:
ISBN 13: OCLC:892867338
Language: EN, FR, DE, ES & NL

Diagnostic Potential of Volatile Organic Compounds and Lactoferrin as Biomarkers in Inflammatory Bowel Disease Book Review:

Volatile Organic Biomarkers in Exhaled Breath as a Rapid Prodromal Diagnosis of Bioagent Infection

Volatile Organic Biomarkers in Exhaled Breath as a Rapid  Prodromal  Diagnosis of Bioagent Infection
Author: Anonim
Publsiher: Unknown
Total Pages: 8
Release: 2004
ISBN 10:
ISBN 13: OCLC:227890819
Language: EN, FR, DE, ES & NL

Volatile Organic Biomarkers in Exhaled Breath as a Rapid Prodromal Diagnosis of Bioagent Infection Book Review:

We have studied the feasibility of using biomarkers in exhaled breath as a prodromal diagnostic for bioagent infection. A compact sampling system was developed and used to collect more than 75 breath samples from 9 piglets. Three of the sampled piglets were uninfected control animals, three were infected with staphylococcal enterotoxin B (SEB), and three with Actinobacillus pleuropneumoniae (A.p.). We found that: volatile markers appeared several hours before outwardly noticeable physical symptoms of illness; volatile profiles for infected piglets were distinct from the uninfected animals and room background air samples; and the volatile profiles for SEB and A.p. were different.