Vaccines

The Vaccine Book, Second Edition provides comprehensive information on the current and future state of vaccines. It reveals the scientific opportunities and potential impact of vaccines, including economic and ethical challenges, problems encountered when producing vaccines, how clinical vaccine trials are designed, and how to introduce vaccines into widespread use. Although vaccines are now available for many diseases, there are still challenges ahead for major diseases, such as AIDS, tuberculosis, and malaria. This book is designed for students, researchers, public health officials, and all others interested in increasing their understanding of vaccines. It answers common questions regarding the use of vaccines in the context of a rapidly expanding anti-vaccine environment. This new edition is completely updated and revised with new and unique topics, including new vaccines, problems of declining immunization rates, trust in vaccines, the vaccine hesitancy, and the social value of vaccines for the community vs. the individual child’s risk. Provides insights into diseases that could be prevented, along with the challenges facing research scientists in the world of vaccines Gives new ideas about future vaccines and concepts Introduces new vaccines and concepts Gives ideas about challenges facing public and private industrial investors in the vaccine area Discusses the problem of declining immunization rates and vaccine hesitancy

2013 BMA Medical Book Awards Highly Commended in Public Health! Apply the latest vaccination knowledge with a reference that Bill Gates calls "an indispensable guide to the enhancement of the well-being of our world." Inside Vaccines, you'll find comprehensive and current coverage of every aspect of vaccination, from the development of each vaccine to its use in reducing disease. This medical reference book offers the expert information you need to apply the very latest techniques and information in your practice! Gain a complete understanding of each disease, including clinical characteristics, microbiology, pathogenesis, diagnosis, and treatment, as well as epidemiology and public health and regulatory issues. Update your knowledge of both existing vaccines and vaccines currently in the research and development stage. Get complete answers on each vaccine, including its stability, immunogenicity, efficacy, duration of immunity, adverse events, indications, contraindications, precautions, administration with other vaccines, and disease-control strategies. Analyze the cost-benefit and cost-effectiveness of different vaccine options. Clearly visualize concepts and objective data through an abundance of tables and figures. Perform seamless searches of the complete text online, access all the references, and download all the images at www.expertconsult.com. Make optimal use of the latest vaccines for pneumococcal disease, rotavirus, human papillomavirus, herpes zoster, meningococcal disease, and much more. Stay at the forefront of new developments with completely updated chapters on malaria and HIV vaccines, a new chapter on vaccine regulations across the world, and many other revisions throughout.

Completely revised and updated, this respected reference offers comprehensive and current coverage of every aspect of vaccination-from development to use in reducing disease. It provides authoritative information on vaccine production, available preparations, efficacy, and safety...recommendations for vaccine use, with rationales...data on the impact of vaccination programs on morbidity and mortality...and more. And now, as an Expert Consult title, it includes a companion web site offering this unparalleled guidance where and when you need it most! Provides a complete understanding of each disease, including clinical characteristics, microbiology, pathogenesis, diagnosis, and treatment, as well an epidemiology and public health issues. Offers comprehensive coverage of both existing vaccines and vaccines currently in the research and development stage. Examines vaccine stability, immunogenicity, efficacy, duration of immunity, adverse events, indications, contraindications, precautions, administration with other vaccines, and disease control strategies. Analyses the cost-benefit and cost-effectiveness of vaccines. Discusses the proper use of immune globulins and antitoxins. Illustrates concepts and objective data with approximately 600 tables and figures. Includes access to a companion web site offering the complete contents of the book - fully searchable - for rapid consultation from anyplace with an Internet connection.

Get a quick, expert overview of the essentials of today’s vaccinations for adults, including current guidelines and recommendations. This concise, clinically-focused resource, edited by Drs. Gregory A. Poland and Jennifer Whitaker, consolidates today’s available information on this important topic into one convenient resource, making it an ideal reference for primary care physicians and nurses who need easily accessible information on adult vaccination best practices.

Apply the latest vaccination knowledge with a reference that Bill Gates calls "an indispensable guide to the enhancement of the well-being of our world." Inside Vaccines, you’ll find comprehensive and current coverage of every aspect of vaccination, from the development of each vaccine to its use in reducing disease. This medical reference book offers the expert information you need to apply the very latest techniques and information in your practice! Consult this title on your favorite e-reader, conduct rapid searches, and adjust font sizes for optimal readability. Gain a complete understanding of each disease, including clinical characteristics, microbiology, pathogenesis, diagnosis, and treatment, as well as epidemiology and public health and regulatory issues. Update your knowledge of both existing vaccines and vaccines currently in the research and development stage. Get complete answers on each vaccine, including its stability, immunogenicity, efficacy, duration of immunity, adverse events, indications, contraindications, precautions, administration with other vaccines, and disease-control strategies. Analyze the cost-benefit and cost-effectiveness of different vaccine options. Clearly visualize concepts and objective data through an abundance of tables and figures. Make optimal use of the latest vaccines for pneumococcal disease, rotavirus, human papillomavirus, herpes zoster, meningococcal disease, and much more. Stay at the forefront of new developments with completely updated chapters on malaria and HIV vaccines, a new chapter on vaccine regulations across the world, and many other revisions throughout.

With contributions by numerous experts

The seventh edition of the Canadian Immunization Guide was developed by the National Advisory Committee on Immunization (NACI), with the support ofthe Immunization and Respiratory Infections Division, Public Health Agency of Canada, to provide updated information and recommendations on the use of vaccines in Canada. The Public Health Agency of Canada conducted a survey in 2004, which confi rmed that the Canadian Immunization Guide is a very useful and reliable resource of information on immunization.

Smallpox, measles, diphtheria, polio: vaccines have diminished their power, and in some cases, eradicated these dreaded diseases. Yet this century has seen growing numbers of parents refusing vaccinations for their children, not only endangering them but also increasing the risk of outbreaks and epidemics of vaccine-preventable diseases. Understanding and Managing Vaccine Concerns concisely explains the evolution of vaccine concerns, and gives clinicians hands-on help in dealing with vaccine hesitation and outright refusal among parents. Persistent themes in refusal, such as a supposed autism/vaccine link and the belief that too many vaccines are given too soon, are discussed and recent statistics given for trends in vaccine refusal and delay. Central to the book is a detailed guide to vaccine concern management, with sample responses that readers can tailor to address vaccine refusal and specific concerns regarding individual vaccines and their components. This thorough grounding will assist providers in countering misinformation with facts and allaying fears with medically and ethically sound responses. Included in this practical resource: A brief history of vaccine concerns. Current trends in vaccine hesitancy and refusal. Health implications of vaccine refusal. Characteristics and beliefs of vaccine-concerned parents. The CASE approach: a management strategy for vaccine concerns. Additional considerations in management strategies. The debate over vaccination isn't going away any time soon and neither is the potential threat to public health, making Understanding and Managing Vaccine Concerns a timely and necessary addition to the libraries of pediatricians, nurses and other healthcare providers.

The Public Health Foundation (PHF) in partnership with the Centers for Disease Control and Prevention (CDC) is pleased to announce the availability of Epidemiology and Prevention of Vaccine-Preventable Diseases, 13th Edition or “The Pink Book” E-Book. This resource provides the most current, comprehensive, and credible information on vaccine-preventable diseases, and contains updated content on immunization and vaccine information for public health practitioners, healthcare providers, health educators, pharmacists, nurses, and others involved in administering vaccines. “The Pink Book E-Book” allows you, your staff, and others to have quick access to features such as keyword search and chapter links. Online schedules and sources can also be accessed directly through e-readers with internet access. Current, credible, and comprehensive, “The Pink Book E-Book” contains information on each vaccine-preventable disease and delivers immunization providers with the latest information on: Principles of vaccination General recommendations on immunization Vaccine safety Child/adult immunization schedules International vaccines/Foreign language terms Vaccination data and statistics The E-Book format contains all of the information and updates that are in the print version, including: · New vaccine administration chapter · New recommendations regarding selection of storage units and temperature monitoring tools · New recommendations for vaccine transport · Updated information on available influenza vaccine products · Use of Tdap in pregnancy · Use of Tdap in persons 65 years of age or older · Use of PCV13 and PPSV23 in adults with immunocompromising conditions · New licensure information for varicella-zoster immune globulin Contact [email protected] for more information. For more news and specials on immunization and vaccines visit the Pink Book's Facebook fan page

The dangerous decline in vaccinations in many developed countries is at the heart of a lively debate that confirms how important the subject is today. Vaccinations are among mankind’s most important scientific discoveries, yet they continue to be viewed with suspicion by part of the public – the victims of disinformation campaigns, instrumentalization and unfounded fears. There is, however, also an evolutionary explanation for these irrational beliefs, and countering the growing social opposition will be extremely difficult without grasping it. This book, which sheds new light on the safety and importance of vaccinations, is intended both for parents and those readers who want to understand the role of vaccinations in contemporary society, where the ease of access to knowledge is both a great opportunity and a great responsibility. The chapters follow a historical progression and conclude with a discussion of the most recent cognitive theories on how to overcome this opposition to vaccinations.

"This book is a concise summary of the results of orthodox medical research into vaccines and their effects. It aims to inform medical professionals, parents of small children and the general public about short and long-term dangerous side-effects, including brain damage and death, of vaccines..." Publisher.

Globally, there has been a move away from national public sector vaccine development over the past 30 years. Immunization and States: The Politics of Making Vaccines explores vaccine geopolitics, analyzing why, and how this move happened, before looking at the ramifications in the context of Covid-19. This unique book uses eight country studies – looking at Croatia, India, Iran, the Netherlands, Romania, Serbia, Spain, and Sweden – to explore the role of public sector vaccine institutes, past and present. Raising questions about national sovereignty, the erosion of multilateralism, and geopolitics, it also contributes to debates around public interest and privatization in the health sector. An extended introduction sets the chapters in an international context, whilst the epilogue looks forward to the future of vaccine development and production. This is an important book for students, scholars, and practitioners with an interest in vaccine development from a range of fields, including public health, medicine, science and technology studies, history of medicine, politics, international relations, and the sociology of health and illness.

This volume is focused on the development of vaccines which generate immune effectors capable of blocking mucosal entry or peripheral pathogen spread. A critical first step in the design of mucosal vaccines is the selection of administration route. Not all mucosal immunization routes are created equally when it comes to eliciting immune responses in multiple body compartments. This subject and situations when a mucosal route may not be required for vaccine delivery are reviewed here with an emphasis on the sublingual immunization route, which may offer a safer alternative to the nasal route for induction of broadly disseminated immune responses. External host defenses that inhibit entry of microorganisms at mucosal surfaces also pose obstacles to the efficient internalization of mucosally-applied vaccines. Transcutaneous immunization with appropriate adjuvants and permeation enhancers can induce mucosal immune responses and may be advantageous for bypassing these luminal barriers. Other chapters describe strategies for enhancing uptake of mucosal vaccines, for instance through targeted delivery to antigen-sampling M cells, construction of virus-like particles which mimic natural pathogens, addition of mucoadhesives or formulation as nanoparticles. Topics include edible vaccines as well as plant-based production of subunit or particulate vaccines that could be administered by any route. Dry powder vaccines that could be insufflated or directly applied to mucosal surfaces may be particularly ideal for mass vaccination in developing countries. The manufacture, stability and efficacy of powder formulations is comprehensively reviewed. We conclude with chapters on two of the greatest challenges facing mucosal vaccine development: human immunodeficiency virus and bioterrorist agents. This monograph highlights progress and information that should prove invaluable for the development of contemporary vaccines that prevent infection by these and other mucosal pathogens.

"The Truth about Vaccination and Immunization" is the 6th book in the "History of Vaccination" series. The 25 books in the “History of Vaccination” series shed light on the history of vaccines through the eyes of doctors, scientists, and historical data. They answer the pressing question, “Are vaccines safe and effective?” The 25 books in the “History of Vaccination” series are: 1) The Poisoned Needle: Suppressed Facts About Vaccination Eleanor McBean, PhD, ND 1957 2) A Century of Vaccination and What It Teaches William Scott Tebb, MA, MD, DPH 1898 3) Vaccination: Proved Useless and Dangerous From 45 Years of Registration Statistics Alfred R. Wallace, LLD DUBL., DCL OXON., FRS, etc. 1885 4) Vaccination: Its Fallacies and Evils Robert A. Gunn, MD 1882 5) Compulsory Vaccination: The Crime Against the School Child Chas. M. (Charles Michael) Higgins 1915 6) The Truth about Vaccination and Immunization Lily Loat, secretary of the National Anti-Vaccination League of London 1951 7) Leicester: Sanitation versus Vaccination Its Vital Statistics Compared with Those of Other Towns, the Army, Navy, Japan, and England and Wales By J.T. Biggs, J.P. 1912 8) The Vaccination Question Arthur Wollaston Hutton, MA 1895 9) Vaccination a Delusion: Its Penal Enforcement a Crime Alfred Russel Wallace, LLD DUBL., DCL OXON., FRS, etc. 1898 10) Vaccination a Curse and Menace to Personal Liberty With Statistics Showing Its Dangers and Criminality James Martin Peebles, MD, MA, PhD Tenth Edition, 1913 11) Dr. C.G.G. Nittinger’s Evils of Vaccination C. Charles Schieferdecker, MD 1856 12) The Vaccination Question in the Light of Modern Experience An Appeal for Reconsideration C. Killick Millard, M.D., D.Sc. 1914 13) Jenner and Vaccination: A Strange Chapter of Medical History Charles Creighton, MD 1889 14) The Horrors of Vaccination: Exposed and Illustrated Charles M. Higgins 1919 15) Vaccination: The Story of a Great Delusion William White 1885 16) Vital Statistics in the United States, 1940-1960 Robert D. Grove, Alice M. Hetzel US Department of Health, Education, and Welfare 1968 17) The Mandatory Vaccination Plan National Immunization Policy Council 1977 18) The Fraud of Vaccination Walter Hadwen, JP., MD, LRCP., MRCS, LSA From "Truth," January 3, 1923 19) Vaccination a Curse C.W. Amerige, MD 1895 20) Vaccination a Medical Fallacy Alexander Wilder, MD 1879 21) The Dream & Lie of Louis Pasteur Originally Pasteur: Plagiarist, Imposter R.B. Pearson 1942 22) The Vaccination Problem Joseph Swan 1936 23) The Fallacy of Vaccination John Pitcairn, President of the Anti-Vaccination League of America 1911 24) The Case Against Vaccination Walter Hadwen, JP, MD, LRCP, MRCS, LSA 1896 25) A Catalogue of Anti-Vaccination Literature The London Society for the Abolition of Compulsory Vaccination 114 Victoria Street, Westminster 1882, 2018 Never Vaccinate Your Child Lessons from Parents, Doctors, Scientists, Media, and HISTORY Trung Nguyen June 2018

What you should know about the Covid-19 vaccines from top experts in the field. As the SARS-Cov2 virus emerged and spread globally in early 2020, unprecedented international efforts began to develop and test vaccines to control the devastating pandemic. This book focuses on the remarkable progress in developing vaccines, the amazing effectiveness of the early vaccines, and the challenges of delivering them to the population. To put this extraordinary progress into perspective, the history of other vaccines is presented and their roles in individual protection and protection of the community, “vaccines that protect the unvaccinated,” are outlined. The rigorous processes whereby vaccines are evaluated in distinct phases and the steps that must be met prior to obtaining regulatory approval for both vaccine safety and effectiveness are highlighted. Multiple vaccine approaches are reviewed, including new approaches such as “messenger or mRNA vaccine” that may revolutionize future vaccine development. The comprehensive models used to provide recommendations and priorities for vaccination of groups of people at risk are summarized. The book also focuses on the questions that remain unanswered after the vaccines are approved. These include duration of immunity, risk factors for vaccine failure, impact of viral evolution and variant strains, and assessment of both immediate and long-term safety. The authors also address concerns about vaccine acceptance including roll-out, access, and detailed and trusted sources of information.

Vaccination, chiefly responsible for the eradication of smallpox and the control of poliomyelitis and German measles in man and of foot-and mouth, Marek's and Newcastle disease in domestic animals, remains the best answer to infectious diseases. Early vaccines were live wild type organ isms but these have been largely replaced by attenuated or killed organisms or by purified components (subunits) thereof. More recently, developments in recombinant DNA techniques, the advent of monoclonal antibodies and progress in our understanding of the immunological structure of proteins, have laid the foundations for a new generation of vaccines. For instance, subuni t vaccines have been produced through gene cloning and a number of peptides mimicking small regions of proteins on the outer coat of viruses and capable of eliciting virus neutralizing antibodies, have been synthes ized. Such vaccines are defined at the molecular level, can elicit immune responses controlling specific infectious organisms and are, thus, potent ially free of the problems inherent in conventional ones. However, because subunit and peptide vaccines are only weakly or non-immunogenic, they re quire the presence of immunological adjuvants. These are a diverse array of agents that promote specific humoural and/or cell-mediated immunity responses to antigens. This book contains the proceedings of the 1st NATO Advanced Studies Institute "Immunological Adjuvants and Vaccines" held in Cape Sounion Beach, Greece during 24 June-5 July, 1988.

How many vaccines that contain unnatural to human biology chemicals can be injected before your children suffer autism or some other condition? The answer is unclear, which is why it is imperative to parents- for the sake of their children's health and very future-to never inject chemicals that could do irreparable harm. The less unnatural to human biology chemicals in vaccines the SAFER our children are. Dr. Robert Caires DC, Esq. inactive, a doctor and lawyer, explains why parents are placed in the uncomfortable position of refusing tovaccinate their children with vaccines that have unhealthy chemicals.Parents will consider SAFER vaccines. This book is a detailed account on how most vaccines are laced with harmful chemicals that can degenerate the health of children and even cause autism. Children deserve SAFER vaccines and parents need to protect children from CHEMICALIZATION! He makes a compelling argument that to assure SAFER vaccines, vaccination should not be mandated and that vaccine producers need to be held accountable and liable for injuries induced by vaccine chemicals.The priority must be safety, but for far too long,it's been all about profits. Be safe, not sorry;only consider SAFER vaccines. The autism epidemic rages on because the main etiology of autism is the unnatural to human biology chemicals in vaccines that penetrate brain cells. Empower yourself, keep your children safe,and help change the system with the insights in Safer Vaccines,Safer Children. Vaccinate with SAFER vaccines approved by SAFER Vaccines Inc. Charity! We need to remove other toxins to assure SAFER vaccines!