Twin and Family Studies of Epigenetics

Twin and Family Studies of Epigenetics
Author: Shuai Li,John Hopper,Trygve Tollefsbol
Publsiher: Elsevier
Total Pages: 374
Release: 2021-08-30
ISBN 10: 0128209518
ISBN 13: 9780128209516
Language: EN, FR, DE, ES & NL

Twin and Family Studies of Epigenetics Book Review:

Twin and Family Studies of Epigenetics, Volume 29, the latest release in the Translational Epigenetics series, gathers expert opinions on epigenetic twin and family study research methods, recent findings across various disease areas, and future directions. The book provides in-depth coverage of epigenetics fundamentals, twin and family epigenetic study design, and the broader role of epigenetics in answering questions on the developmental origins of health and disease. Throughout the volume, twin and family studies are employed to examine causes of epigenetic variation, the relationship between epigenetic modifications and mental illness, cancers, cardiovascular disease, diabetes, obesity, high blood pressure, and more. Emerging research methods applied in twin and family studies discussed include imaging epigenetics, exposure-specific DNA methylation changes, and unravelling time trends in epigenetic effects. Offers a practical, interdisciplinary approach across epigenetics, epidemiology and various disease specialties Applies epigenetic twin and family studies to determine the relationship between epigenetics and mental illness, cancers, cardiovascular disease, diabetes, obesity and high blood pressure, among other diseases and disorders Features chapter contributions from a wide range of international researchers in the field

Twin and Family Studies of Epigenetics

Twin and Family Studies of Epigenetics
Author: Shuai Li,John Hopper
Publsiher: Academic Press
Total Pages: 374
Release: 2021-08-31
ISBN 10: 0128209526
ISBN 13: 9780128209523
Language: EN, FR, DE, ES & NL

Twin and Family Studies of Epigenetics Book Review:

Twin and Family Studies of Epigenetics, Volume 29, the latest release in the Translational Epigenetics series, gathers expert opinions on epigenetic twin and family study research methods, recent findings across various disease areas, and future directions. The book provides in-depth coverage of epigenetics fundamentals, twin and family epigenetic study design, and the broader role of epigenetics in answering questions on the developmental origins of health and disease. Throughout the volume, twin and family studies are employed to examine causes of epigenetic variation, the relationship between epigenetic modifications and mental illness, cancers, cardiovascular disease, diabetes, obesity, high blood pressure, and more. Emerging research methods applied in twin and family studies discussed include imaging epigenetics, exposure-specific DNA methylation changes, and unravelling time trends in epigenetic effects. Offers a practical, interdisciplinary approach across epigenetics, epidemiology and various disease specialties Applies epigenetic twin and family studies to determine the relationship between epigenetics and mental illness, cancers, cardiovascular disease, diabetes, obesity and high blood pressure, among other diseases and disorders Features chapter contributions from a wide range of international researchers in the field

The Epigenetics Revolution

The Epigenetics Revolution
Author: Nessa Carey
Publsiher: Columbia University Press
Total Pages: 352
Release: 2012-03-06
ISBN 10: 0231530714
ISBN 13: 9780231530712
Language: EN, FR, DE, ES & NL

The Epigenetics Revolution Book Review:

Epigenetics can potentially revolutionize our understanding of the structure and behavior of biological life on Earth. It explains why mapping an organism's genetic code is not enough to determine how it develops or acts and shows how nurture combines with nature to engineer biological diversity. Surveying the twenty-year history of the field while also highlighting its latest findings and innovations, this volume provides a readily understandable introduction to the foundations of epigenetics. Nessa Carey, a leading epigenetics researcher, connects the field's arguments to such diverse phenomena as how ants and queen bees control their colonies; why tortoiseshell cats are always female; why some plants need cold weather before they can flower; and how our bodies age and develop disease. Reaching beyond biology, epigenetics now informs work on drug addiction, the long-term effects of famine, and the physical and psychological consequences of childhood trauma. Carey concludes with a discussion of the future directions for this research and its ability to improve human health and well-being.

Epigenetic Epidemiology

Epigenetic Epidemiology
Author: Karin B. Michels
Publsiher: Springer Science & Business Media
Total Pages: 448
Release: 2012-01-02
ISBN 10: 9400724950
ISBN 13: 9789400724952
Language: EN, FR, DE, ES & NL

Epigenetic Epidemiology Book Review:

The exploding field of epigenetics is challenging the dogma of traditional Mendelian inheritance. Epigenetics plays an important role in shaping who we are and contributes to our prospects of health and disease. While early epigenetic research focused on plant and animal models and in vitro experiments, population-based epidemiologic studies increasingly incorporate epigenetic components. The relevance of epigenetic marks, such as DNA methylation, genomic imprinting, and histone modification for disease causation has yet to be fully explored. This book covers the basic concepts of epigenetic epidemiology, discusses challenges in study design, analysis, and interpretation, epigenetic laboratory techniques, the influence of of age and environmental factors on shaping the epigenome, the role of epigenetics in the developmental origins hypothesis, and provides the state of the art on the epigenetic epidemiology of various health conditions including childhood syndromes, cancer, infectious diseases, inflammation and rheumatoid arthritis, asthma, autism and other neurodevelopmental disorders, psychiatric disorders, diabetes, obesity and metabolic disorders, and atherosclerosis. With contributions from: Peter Jones, Jean-Pierre Issa, Gavin Kelsey, Robert Waterland, and many other experts in epigenetics!

Twin Research

Twin Research
Author: Adam D. Tarnoki,David L. Tarnoki,Jennifer Harris,Nancy L. Segal
Publsiher: Academic Press
Total Pages: 424
Release: 2022-04-15
ISBN 10: 9780128215142
ISBN 13: 0128215143
Language: EN, FR, DE, ES & NL

Twin Research Book Review:

Twin Research: Biology, Health, Epigenetics, and Psychology stands as a comprehensive, applied resource in twinning and twin studies, grounded in the most impactful findings from twin research in recent years. Here, more than forty leading experts across an array of disciplines examine twinning and twin research methodology from the perspectives of biology, medicine, genetic and epigenetic influences, and neuroscience. Chapters provide clear instruction in both basic and advanced research methods; family and parenting aspects of twinning; twin studies as applied across various disease areas and medical specialties; genetic and epigenetic determinants of differentiation; and academic, neurological, and cognitive development of twins. Thorough analysis of existing studies and methods instruction empowers researchers to apply twin-based research and advance new studies across a range of biomedical and behavioral fields, highlighting current research trends and future directions. Offers unique insights into twinning rates and mechanisms and factors surrounding twinship Provides clear instruction in both basic and advanced twin research methods and study design Features leading international experts in twin biology, genetics, health, and psychology Examines findings from recent twin studies across a broad array of health and behavioral studies

Born Together Reared Apart

Born Together   Reared Apart
Author: Nancy L. Segal
Publsiher: Harvard University Press
Total Pages: 416
Release: 2012-06-18
ISBN 10: 0674065158
ISBN 13: 9780674065154
Language: EN, FR, DE, ES & NL

Born Together Reared Apart Book Review:

The Minnesota Study of Twins Reared Apart startled scientists by demonstrating that twins reared apart are as alike, across a number of personality traits and other measures, as those raised together, suggesting that genetic influence is pervasive. Segal offers an overview of the study’s scientific contributions and effect on public consciousness.

Medical Epigenetics

Medical Epigenetics
Author: Anonim
Publsiher: Academic Press
Total Pages: 970
Release: 2021-08-27
ISBN 10: 0128243260
ISBN 13: 9780128243268
Language: EN, FR, DE, ES & NL

Medical Epigenetics Book Review:

Medical Epigenetics, Second Edition provides a comprehensive analysis of epigenetics in health management, across a broad spectrum of disease categories and specialties, and with a focus on human systems, epigenetic diseases that affect these systems, and evolving modes of epigenetic-based treatment. Here, more than 40 leading researchers examine how each human system is affected by epigenetic maladies, offering an all-in-one resource on medical epigenetics not only for those directly involved with health care, but investigators in life sciences, biotech companies, graduate students, and others who are interested in applied aspects of epigenetics. Incorporating both diagnostic and prognostic epigenetic approaches, this volume also fully supports the application of epigenetics in precision medicine. This second edition of Medical Epigenetics, a volume in the Translational Epigenetics series, has been fully revised to address recent advances in disease epigenetics and role of epigenetics in precision medicine, with all-new chapters on skin cancer epigenetics, network analysis in medical epigenetics, machine learning in epigenetic diseases, and clinical trials of epigenetics drugs. Features chapters from leading researchers and clinicians dedicated to the burgeoning role of epigenetics in medical practice Covers emerging topics, including twin epigenetics, as well as epigenetics of gastrointestinal disease, muscle disorders, endocrine disorders, ocular medicine, pediatric diseases, sports medicine, noncoding RNA therapeutics, pain management and regenerative medicine Organized from system disorders to multi-system disorders that involve epigenetic aberrations Examines the role of epigenetics in precision medicine

Epigenetics of Aging

Epigenetics of Aging
Author: Trygve O. Tollefsbol
Publsiher: Springer Science & Business Media
Total Pages: 469
Release: 2009-11-11
ISBN 10: 1441906398
ISBN 13: 9781441906397
Language: EN, FR, DE, ES & NL

Epigenetics of Aging Book Review:

Recent studies have indicated that epigenetic processes may play a major role in both cellular and organismal aging. These epigenetic processes include not only DNA methylation and histone modifications, but also extend to many other epigenetic mediators such as the polycomb group proteins, chromosomal position effects, and noncoding RNA. The topics of this book range from fundamental changes in DNA methylation in aging to the most recent research on intervention into epigenetic modifications to modulate the aging process. The major topics of epigenetics and aging covered in this book are: 1) DNA methylation and histone modifications in aging; 2) Other epigenetic processes and aging; 3) Impact of epigenetics on aging; 4) Epigenetics of age-related diseases; 5) Epigenetic interventions and aging: and 6) Future directions in epigenetic aging research. The most studied of epigenetic processes, DNA methylation, has been associated with cellular aging and aging of organisms for many years. It is now apparent that both global and gene-specific alterations occur not only in DNA methylation during aging, but also in several histone alterations. Many epigenetic alterations can have an impact on aging processes such as stem cell aging, control of telomerase, modifications of telomeres, and epigenetic drift can impact the aging process as evident in the recent studies of aging monozygotic twins. Numerous age-related diseases are affected by epigenetic mechanisms. For example, recent studies have shown that DNA methylation is altered in Alzheimer’s disease and autoimmunity. Other prevalent diseases that have been associated with age-related epigenetic changes include cancer and diabetes. Paternal age and epigenetic changes appear to have an effect on schizophrenia and epigenetic silencing has been associated with several of the progeroid syndromes of premature aging. Moreover, the impact of dietary or drug intervention into epigenetic processes as they affect normal aging or age-related diseases is becoming increasingly feasible.

Environmental Epigenetics

Environmental Epigenetics
Author: L. Joseph Su,Tung-chin Chiang
Publsiher: Springer
Total Pages: 321
Release: 2015-05-18
ISBN 10: 1447166787
ISBN 13: 9781447166788
Language: EN, FR, DE, ES & NL

Environmental Epigenetics Book Review:

This book examines the toxicological and health implications of environmental epigenetics and provides knowledge through an interdisciplinary approach. Included in this volume are chapters outlining various environmental risk factors such as phthalates and dietary components, life states such as pregnancy and ageing, hormonal and metabolic considerations and specific disease risks such as cancer cardiovascular diseases and other non-communicable diseases. Environmental Epigenetics imparts integrative knowledge of the science of epigenetics and the issues raised in environmental epidemiology. This book is intended to serve both as a reference compendium on environmental epigenetics for scientists in academia, industry and laboratories and as a textbook for graduate level environmental health courses. Environmental Epigenetics imparts integrative knowledge of the science of epigenetics and the issues raised in environmental epidemiology. This book is intended to serve both as a reference compendium on environmental epigenetics for scientists in academia, industry and laboratories and as a textbook for graduate level environmental health courses.

Epigenetics in Society

Epigenetics in Society
Author: Windsor Epigenetics Study Group
Publsiher: University of Windsor
Total Pages: 327
Release: 2015-10-26
ISBN 10: 0920233724
ISBN 13: 9780920233726
Language: EN, FR, DE, ES & NL

Epigenetics in Society Book Review:

This is a book written by students of diverse disciplines, and intended for students and educated lay people. We intend this book to serve several functions. First, we want to make the field of epigenetics accessible to lay readers. Second, and more importantly, we want to excite further interest and concern regarding the social, ethical, legal, health, and policy implications that this field will have for all arenas of our lives. Third, we want to arm our readers with knowledge and wariness so that they can understand and critique the nuanced debates that will inevitably arise when costs and benefits must be weighed: while the effects of epigenetics upon us as individuals may be subtle, the demographic implications and costs are huge.

Identically Different

Identically Different
Author: Tim Spector
Publsiher: ABRAMS
Total Pages: 352
Release: 2014-07-30
ISBN 10: 1468310402
ISBN 13: 9781468310405
Language: EN, FR, DE, ES & NL

Identically Different Book Review:

In this book, a geneticist who studies identical twins “treats the view that genes are destiny with skepticism” (The New York Times). How much are the things you choose to do every day determined by your genes and how much is your own free will? Drawing on his own cutting-edge research of identical twins, leading geneticist Tim Spector shows us how the same upbringing, the same environment, and even the same exact genes can lead to very different outcomes. Thought-provoking, entertaining, and enlightening, Identically Different helps us understand the science behind what makes each of us unique and so quintessentially human.

Compulsive Eating Behavior and Food Addiction

Compulsive Eating Behavior and Food Addiction
Author: Pietro Cottone,Catherine F Moore,Valentina Sabino,George F. Koob
Publsiher: Academic Press
Total Pages: 496
Release: 2019-07-24
ISBN 10: 0128163836
ISBN 13: 9780128163832
Language: EN, FR, DE, ES & NL

Compulsive Eating Behavior and Food Addiction Book Review:

Compulsive Eating Behavior and Food Addiction: Emerging Pathological Constructs is the first book of its kind to emphasize food addiction as an addictive disorder. This book focuses on the preclinical aspects of food addiction research, shifting the focus towards a more complex behavioral expression of pathological feeding and combining it with current research on neurobiological substrates. This book will become an invaluable reference for researchers in food addiction and compulsive eating constructs. Compulsive eating behavior is a pathological form of feeding that phenotypically and neurobiologically resembles the compulsive-like behaviors associated with both drug abuse and behavioral addictions. Compulsive eating behavior, including Binge Eating Disorder (BED), certain forms of obesity, and ‘food addiction’ affect an estimated 70 million individuals worldwide. Synthesizes clinical and preclinical perspectives on addictive eating behavior Identifies how food addiction is similar and/or different from other addictions Focuses on the underlying neurobiological mechanisms Provides information on therapeutic interventions for patients with food addiction

Epigenetics and Metabolomics

Epigenetics and Metabolomics
Author: Paban K. Agrawala,Poonam Rana
Publsiher: Elsevier
Total Pages: 476
Release: 2021-08-25
ISBN 10: 0323856535
ISBN 13: 9780323856539
Language: EN, FR, DE, ES & NL

Epigenetics and Metabolomics Book Review:

Epigenetics and Metabolomics, a new volume in the Translational Epigenetics series, offers a synthesized discussion of epigenetic control of metabolic activity, and systems-based approaches for better understanding these mechanisms. Over a dozen chapter authors provide an overview of epigenetics in translational medicine and metabolomics techniques, followed by analyses of epigenetic and metabolomic linkage mechanisms likely to result in effective identification of disease biomarkers, as well as new therapies targeting the removal of the inappropriate epigenetic alterations. Epigenetic interventions in cancer, brain damage, and neuroendocrine disease, among other disorders, are discussed in-depth, with an emphasis on exploring next steps for clinical translation and personalized healthcare. Offers a synthesized discussion of epigenetic regulation of metabolic activity and systems-based approaches to power new research Discusses epigenetic control of metabolic pathways and possible therapeutic targets for cancer, neurodegenerative, and neuroendocrine diseases, among others Provides guidance in epigenomics and metabolomic research methodology

Developmental Human Behavioral Epigenetics

Developmental Human Behavioral Epigenetics
Author: Livio Provenzi,Rosario Montirosso
Publsiher: Academic Press
Total Pages: 188
Release: 2020-11-12
ISBN 10: 0128192631
ISBN 13: 9780128192634
Language: EN, FR, DE, ES & NL

Developmental Human Behavioral Epigenetics Book Review:

Developmental Human Behavioral Epigenetics: Principles, Methods, Evidence, and Future Directions, Volume 23, a new volume in the Translational Epigenetics series, offers the first systematic account of theoretical G79 frameworks, methodological approaches, findings, and future directions in the field of human behavioral epigenetics. Featuring contributions from leading scientists and international researchers, this book provides a comprehensive overview of human behavioral epigenetics, with a close examination of evidence gathered to-date from animal models, challenges of human-based research and clinical translation, pathways towards drug discovery, and next steps in research. Areas of focus include prenatal stress exposures, preterm behavioral epigenetics, intergenerational exposures, trauma and neglect, socio-economic conditions, maternal caregiving and attachment, study design, and epigenetics and psychotherapy. Enables more effective study design and methods application in behavioral epigenetics research across human and animal models Examines findings in human behavioral epigenetics to-date Features contributions from leading international researchers in behavioral epigenetics

Accidental Brothers

Accidental Brothers
Author: Dr. Nancy L. Segal,Yesika S. Montoya
Publsiher: St. Martin's Press
Total Pages: 256
Release: 2018-04-17
ISBN 10: 1250101913
ISBN 13: 9781250101914
Language: EN, FR, DE, ES & NL

Accidental Brothers Book Review:

"A unique window into human behavior and development." —Steven Pinker The riveting story of two sets of identical twins separated at birth and improbably reunited as adults, a dream case for exploring nature and nurture. Accidental Brothers tells the unique story of two sets of identical Colombian twin brothers who discovered at age 25 that they were mistakenly raised as fraternal twins—when they were not even biological brothers. Due to an oversight that presumably occurred in the hospital nursery, one twin in each pair was switched with a twin in the other pair. The result was two sets of unrelated “fraternal” twins—Jorge and Carlos, who were raised in the lively city of Bogotá; and William and Wilber, who were raised in the remote rural village of La Paz, 150 miles away. Their parents and siblings were aware of the enormous physical and behavioral differences between the members of each set, but never doubted that the two belonged in their biological families. Everyone’s life unraveled when one of the twins—William—was mistaken by a young woman for his real identical twin, Jorge. Her “discovery” led to the truth—that the alleged twins were not twins at all, but rather unrelated individuals who ended up with the wrong families. Blending great science and human interest, Accidental Brothers by Nancy L. Segal and Yesika S. Montoya will inform and entertain anyone interested in how twin studies illuminate the origins of human behavior, as well as mother-infant identification and the chance events that can have profound consequences on our lives.

Epigenetics in Human Disease

Epigenetics in Human Disease
Author: Trygve O. Tollefsbol
Publsiher: Academic Press
Total Pages: 577
Release: 2012
ISBN 10: 0123884152
ISBN 13: 9780123884152
Language: EN, FR, DE, ES & NL

Epigenetics in Human Disease Book Review:

Epigenetics is one of the fastest growing fields of sciences, illuminating studies of human diseases by looking beyond genetic make-up and acknowledging that outside factors play a role in gene expression. The goal of this volume is to highlight those diseases or conditions for which we have advanced knowledge of epigenetic factors such as cancer, autoimmune disorders and aging as well as those that are yielding exciting breakthroughs in epigenetics such as diabetes, neurobiological disorders and cardiovascular disease. Where applicable, attempts are made to not only detail the role of epigenetics in the etiology, progression, diagnosis and prognosis of these diseases, but also novel epigenetic approaches to the treatment of these diseases. Chapters are also presented on human imprinting disorders, respiratory diseases, infectious diseases and gynecological and reproductive diseases. Since epigenetics plays a major role in the aging process, advances in the epigenetics of aging are highly relevant to many age-related human diseases. Therefore, this volume closes with chapters on aging epigenetics and breakthroughs that have been made to delay the aging process through epigenetic approaches. With its translational focus, this book will serve as valuable reference for both basic scientists and clinicians alike. Comprehensive coverage of fundamental and emergent science and clinical usage Side-by-side coverage of the basis of epigenetic diseases and their treatments Evaluation of recent epigenetic clinical breakthroughs

Twin Studies

Twin Studies
Author: Grant C Townsend,Sandra K Pinkerton,James R Rogers,Michelle R Bockmann,Toby E Hughes
Publsiher: University of Adelaide Press
Total Pages: 216
Release: 2015-10-08
ISBN 10: 1925261158
ISBN 13: 9781925261158
Language: EN, FR, DE, ES & NL

Twin Studies Book Review:

This volume is about an ongoing long-term research initiative led by researchers from the School of Dentistry at the University of Adelaide. The aim of this book is to provide an overview of the studies of the teeth and faces of Australian twins and their families that have extended over more than thirty years.

The Gene

The Gene
Author: Siddhartha Mukherjee
Publsiher: Simon and Schuster
Total Pages: 608
Release: 2016-05-17
ISBN 10: 1476733538
ISBN 13: 9781476733531
Language: EN, FR, DE, ES & NL

The Gene Book Review:

The #1 NEW YORK TIMES Bestseller The basis for the PBS Ken Burns Documentary The Gene: An Intimate History From the Pulitzer Prize–winning author of The Emperor of All Maladies—a fascinating history of the gene and “a magisterial account of how human minds have laboriously, ingeniously picked apart what makes us tick” (Elle). "Sid Mukherjee has the uncanny ability to bring together science, history, and the future in a way that is understandable and riveting, guiding us through both time and the mystery of life itself." –Ken Burns “Dr. Siddhartha Mukherjee dazzled readers with his Pulitzer Prize-winning The Emperor of All Maladies in 2010. That achievement was evidently just a warm-up for his virtuoso performance in The Gene: An Intimate History, in which he braids science, history, and memoir into an epic with all the range and biblical thunder of Paradise Lost” (The New York Times). In this biography Mukherjee brings to life the quest to understand human heredity and its surprising influence on our lives, personalities, identities, fates, and choices. “Mukherjee expresses abstract intellectual ideas through emotional stories…[and] swaddles his medical rigor with rhapsodic tenderness, surprising vulnerability, and occasional flashes of pure poetry” (The Washington Post). Throughout, the story of Mukherjee’s own family—with its tragic and bewildering history of mental illness—reminds us of the questions that hang over our ability to translate the science of genetics from the laboratory to the real world. In riveting and dramatic prose, he describes the centuries of research and experimentation—from Aristotle and Pythagoras to Mendel and Darwin, from Boveri and Morgan to Crick, Watson and Franklin, all the way through the revolutionary twenty-first century innovators who mapped the human genome. “A fascinating and often sobering history of how humans came to understand the roles of genes in making us who we are—and what our manipulation of those genes might mean for our future” (Milwaukee Journal-Sentinel), The Gene is the revelatory and magisterial history of a scientific idea coming to life, the most crucial science of our time, intimately explained by a master. “The Gene is a book we all should read” (USA TODAY).

Behavior Genetics of Psychopathology

Behavior Genetics of Psychopathology
Author: Soo Hyun Rhee,Angelica Ronald
Publsiher: Springer Science & Business Media
Total Pages: 344
Release: 2014-02-03
ISBN 10: 1461495091
ISBN 13: 9781461495093
Language: EN, FR, DE, ES & NL

Behavior Genetics of Psychopathology Book Review:

As a dynamic, interdisciplinary field, behavior genetics and its evolution are being followed closely by scientists across the psychological and medical domains. The discoveries surrounding the human genome and the advancement in molecular genetic technologies have led to studies becoming increasingly sophisticated and yielding yet more conclusive and useful results. This is certainly the case in the area of child and adult psychopathology. Behavior Genetics of Psychopathology summarizes the state of the field, examining the role of genes and environment as they affect common neurodevelopmental and psychiatric conditions. Emphasizing key research areas (comorbidities, twin studies, the integration of methods), the book assesses the current literature, offers up-to-date findings, sorts through lingering controversies, and identifies a clear future agenda for the field. Expertly-written chapters focus on issues of both general salience that shape behavior genetics of psychopathology, to specific disorders of major clinical importance, among them: ADHD: the view from quantitative genetic research. Autism spectrum disorders and their complex heterogeneity Genetic influences on anxiety and depression in childhood and adolescence. Evidence for etiologically-defined subgroups within the construct of antisocial behavior. Sleep and psychopathology: the reasons for their co-occurrence. Behavioral genetic approaches to the etiology of comorbidity. Epigenetics of psychopathology. This combination of timeliness and depth of coverage make Behavior Genetics of Psychopathology a frontline resource for behavior geneticists, psychologists, psychiatrists, and neuroscientists, and is perfectly suited to graduate students looking to join these fields.

She Has Her Mother s Laugh

She Has Her Mother s Laugh
Author: Carl Zimmer
Publsiher: Penguin
Total Pages: 672
Release: 2018-05-29
ISBN 10: 1101984600
ISBN 13: 9781101984604
Language: EN, FR, DE, ES & NL

She Has Her Mother s Laugh Book Review:

2019 PEN/E.O. Wilson Literary Science Writing Award Finalist "Science book of the year"—The Guardian One of New York Times 100 Notable Books for 2018 One of Publishers Weekly's Top Ten Books of 2018 One of Kirkus's Best Books of 2018 One of Mental Floss's Best Books of 2018 One of Science Friday's Best Science Books of 2018 “Extraordinary”—New York Times Book Review "Magisterial"—The Atlantic "Engrossing"—Wired "Leading contender as the most outstanding nonfiction work of the year"—Minneapolis Star-Tribune Celebrated New York Times columnist and science writer Carl Zimmer presents a profoundly original perspective on what we pass along from generation to generation. Charles Darwin played a crucial part in turning heredity into a scientific question, and yet he failed spectacularly to answer it. The birth of genetics in the early 1900s seemed to do precisely that. Gradually, people translated their old notions about heredity into a language of genes. As the technology for studying genes became cheaper, millions of people ordered genetic tests to link themselves to missing parents, to distant ancestors, to ethnic identities... But, Zimmer writes, “Each of us carries an amalgam of fragments of DNA, stitched together from some of our many ancestors. Each piece has its own ancestry, traveling a different path back through human history. A particular fragment may sometimes be cause for worry, but most of our DNA influences who we are—our appearance, our height, our penchants—in inconceivably subtle ways.” Heredity isn’t just about genes that pass from parent to child. Heredity continues within our own bodies, as a single cell gives rise to trillions of cells that make up our bodies. We say we inherit genes from our ancestors—using a word that once referred to kingdoms and estates—but we inherit other things that matter as much or more to our lives, from microbes to technologies we use to make life more comfortable. We need a new definition of what heredity is and, through Carl Zimmer’s lucid exposition and storytelling, this resounding tour de force delivers it. Weaving historical and current scientific research, his own experience with his two daughters, and the kind of original reporting expected of one of the world’s best science journalists, Zimmer ultimately unpacks urgent bioethical quandaries arising from new biomedical technologies, but also long-standing presumptions about who we really are and what we can pass on to future generations.