Acquired Long QT Syndrome

Acquired Long QT Syndrome
Author: A. John Camm,Marek Malik,Yee Guan Yap
Publsiher: John Wiley & Sons
Total Pages: 208
Release: 2008-04-15
ISBN 10: 1405146168
ISBN 13: 9781405146166
Language: EN, FR, DE, ES & NL

Acquired Long QT Syndrome Book Review:

In recent years there has been considerable interest in the diagnosis and understanding of ventricular repolarisation, particularly the QT interval prolongation and abnormal T and T/U wave morphology associated with torsades de pointes. Advances in ion channel cloning have greatly improved our understanding of the role of ionic channels in mediating cardiac repolarisation. Unfortunately, it is increasingly recognised that a number of drugs, both those associated with altering repolarisation, and others for non-cardiac conditions can increase the propensity for polymorphic ventricular tachycardia, syncope and even ventricular fibrillation and sudden death. In this volume, arrhythmia specialists from St. George’s Hospital Medical School, London discuss the mechanisms behind QT prolongation and torsades de pointes. They focus particularly on the risk of individual cardiac and non-cardiac drugs in provoking long QT syndrome, providing a comprehensive review which will be useful for all electrophysiologists treating polymorphic ventricular tachycardias, and will expose important regulatory issues for pharmaceutical authorities and for the wider medical community.

Torsades de Pointes

Torsades de Pointes
Author: James E Tisdale
Publsiher: Academic Press
Total Pages: 310
Release: 2021-08-01
ISBN 10: 0128214619
ISBN 13: 9780128214619
Language: EN, FR, DE, ES & NL

Torsades de Pointes Book Review:

Over the past 25-30 years, deaths due to Torsades de Pointes (TdP) have resulted in numerous drugs being withdrawn from the market. However, nearly 200 drugs that may prolong the QT interval and cause TdP remain available. A number of drugs with the potential to cause TdP are among the top 200 most prescribed drugs in the US, whilst new information regarding TdP is emerging rapidly. The purpose of this book is to provide a comprehensive source of information on the topic of torsades de pointes (TdP), which is a life-threatening polymorphic ventricular tachyarrhythmia associated with QT interval prolongation on the electrocardiogram (ECG). Torsades de Pointes provides a detailed, up-to-date and emerging information related to the epidemiology, drug culprits, mechanisms, risk factors, and methods of prevention and management of the life-threatening polymorphic ventricular tachycardia, also known as torsades de pointes. The book contains current knowledge, incorporating recent and cutting-edge advances in understanding of topics including inherited channelopathies and congenital LQTS; drugs that cause QT interval prolongation and TdP; non-drug causes of acquired QT interval prolongation and TdP; epidemiology of inherited and acquired TdP; morbidity and mortality associated with TdP, particularly in association with specific antimicrobials, antidepressants and antipsychotics, and methadone; cellular and molecular mechanisms of TdP, traditional and emerging risk factors for TdP; methods of prevention and risk reduction for TdP; and clinical management of patients with TdP. This book is an essential reference for both clinicians and researchers – providing guidance for clinicians who care for patients receiving QT interval-prolonging drugs, as well as cutting edge information for scientists and investigators conducting research in the area. Up-to-date information on TdP associated with inherited channelopathies and the multiple forms of congenital LQTS Includes a wealth of new information emerging regarding TdP, including newly-described risk factors and cellular and molecular mechanisms, contributions of genetic polymorphisms to drug-induced TdP, methods of quantification of risk, and methods of risk reduction, including clinical decision support Contains information on nearly 200 commonly used drugs that have the potential to cause torsades de pointes, including antimicrobials, antipsychotics, antidepressants, antiarrhythmic agents, methadone, and many others An essential reference for clinicians and researchers – provides guidance for clinicians who care for patients receiving QT interval-prolonging drugs, as well as cutting edge information for scientists and investigators conducting research in the area

Safety Pharmacology Risk Assessment QT Interval Prolongation and Beyond

Safety Pharmacology   Risk Assessment QT Interval Prolongation and Beyond
Author: Esther Pueyo,Blanca Rodriguez
Publsiher: Frontiers Media SA
Total Pages: 329
Release: 2018-08-16
ISBN 10: 2889455394
ISBN 13: 9782889455393
Language: EN, FR, DE, ES & NL

Safety Pharmacology Risk Assessment QT Interval Prolongation and Beyond Book Review:

Current regulatory guidelines for cardiac safety utilize hERG block and QT interval prolongation as risk markers. This strategy has been successful at preventing harmful drugs from being marketed, but criticized for leading to early withdrawal of potentially safe drugs. Here we collected a series of articles presenting new technological and conceptual advances, including refinement of ex vivo and in vitro assays, screens and models, and in silico approaches reflecting the increasing effort that has been put forward by regulatory agencies, industry, and academia to try and address the need of a more accurate, mechanistically-based paradigm of proarrhythmic potential of drugs. This Research Topic is dedicated to the memory of Dr. J. Jeremy Rice, our wonderful friend and colleague.

Clinical Arrhythmology and Electrophysiology E Book

Clinical Arrhythmology and Electrophysiology E Book
Author: Ziad Issa,John M. Miller,Douglas P. Zipes
Publsiher: Elsevier Health Sciences
Total Pages: 752
Release: 2018-08-07
ISBN 10: 0323568823
ISBN 13: 9780323568821
Language: EN, FR, DE, ES & NL

Clinical Arrhythmology and Electrophysiology E Book Book Review:

Part of the highly regarded Braunwald’s family of cardiology references, Clinical Arrhythmology and Electrophysiology, 3rd Edition, offers complete coverage of the latest diagnosis and management options for patients with arrhythmias. Expanded clinical content and clear illustrations keep you fully abreast of current technologies, new syndromes and diagnostic procedures, new information on molecular genetics, advances in ablation, and much more.

Cardiac Repolarization

Cardiac Repolarization
Author: Nabil El-Sherif
Publsiher: Springer Nature
Total Pages: 354
Release: 2019-10-24
ISBN 10: 3030226727
ISBN 13: 9783030226725
Language: EN, FR, DE, ES & NL

Cardiac Repolarization Book Review:

This book provides a comprehensive, up-to-date overview of clinical and research aspects of cardiac repolarization geared toward practicing cardiologists and physicians. It analyzes elements of pathophysiology and molecular biology as they relate to the clinical aspects of cardiac repolarization, long QT syndromes, early repolarization syndromes, and special cardiac repolarization syndromes. Each chapter examines different aspects of the field with basic and clinical overviews and highlights the impact on medical management. The book covers a variety of repolarization topics including the influence of the autonomic system, racial and gender differences in patients, the future role of stem cells, inflammation and autoimmunity, and cardiovascular risk. Cardiac Repolarization: Basic Science and Clinical Management is an essential resource for physicians and related professionals, residents, fellows, and graduate students in cardiology, clinical cardiac electrophysiology, internal medicine, and cardiovascular biology.

Sex and Cardiac Electrophysiology

Sex and Cardiac Electrophysiology
Author: Marek Malik
Publsiher: Academic Press
Total Pages: 1032
Release: 2020-07-11
ISBN 10: 0128177292
ISBN 13: 9780128177297
Language: EN, FR, DE, ES & NL

Sex and Cardiac Electrophysiology Book Review:

Sex and Cardiac Electrophysiology: Differences in Cardiac Electrical Disorders Between Men and Women is a comprehensive investigation into all aspects of sex differences in cardiac electrophysiology. As there are substantial differences between female and male patients in physiology, pathology triggering factors, disease progression, clinical approaches and treatment outcome, this book provides a comprehensive examination. In cardiology, the differences between women and men are more recognized, hence this title summarizes these important differences, providing the essential information needed for clinical specialists and researchers involved in the design and implementation of clinical studies. Explores topics ranging from the physiologic differences between women and men to the differences in clinical handling of arrhythmic disorders between female and male patients Provides sex differences in cardiac electrophysiology in separate chapters Covers the sex differences of cardiac electrical disorders, providing insights beyond cardiac metabolic syndrome, hypertension, atherogenesis and heart failure

The Prevention of Sudden Cardiac Death

The Prevention of Sudden Cardiac Death
Author: John B. Kostis,Michael Sanders
Publsiher: Wiley-Liss
Total Pages: 305
Release: 1990-03-19
ISBN 10:
ISBN 13: UOM:39015017753420
Language: EN, FR, DE, ES & NL

The Prevention of Sudden Cardiac Death Book Review:

Presenting the latest diagnostic and therapeutic developments in a multifaceted field, this book addresses the problems involved in preventing sudden cardiac death (SCD), focusing on risk stratification techniques designed to direct the selection and application of appropriate treatment modalities. Material reflects recent discoveries concerning the epidemiology and SCD pathophysiology, offering guidelines for more rational treatment approaches, both pharmacologic and interventional. The text reviews the vast epidemiologic data from the Framingham Study, with special emphasis on identifying clinical risk factors and the relation of coronary heart disease to SCD. It also details the background for risk stratification based on well-established exercise testing and ambulatory electrocardiography techniques, as well as newer methods of electrophysiologic testing and signal average electrocardiography. Current prevention strategies--lifestyle alteration, prospective drug trials, surgical and implantable devices--are also discussed.

Challenging Cases and Complication Management in Pain Medicine

Challenging Cases and Complication Management in Pain Medicine
Author: Magdalena Anitescu,Honorio T. Benzon,Mark S. Wallace
Publsiher: Springer
Total Pages: 346
Release: 2017-11-17
ISBN 10: 3319600729
ISBN 13: 9783319600727
Language: EN, FR, DE, ES & NL

Challenging Cases and Complication Management in Pain Medicine Book Review:

This comprehensive book provides reviews of pain management complications that arise in clinical practice. Organized into sections focused on types of pain therapy and procedures, each chapter is based on actual complications; starting with a case description that delineates the context with a short past medical and surgical history, pain management technique and outcome it is followed by a comprehensive review of the topic described in the first section. Authors emphasize the elements of differential diagnosis that pointed towards establishing of the complication and describe the best way to treat the identified complication. Physicians treating pain patients will be presented the necessary tools in identifying and treating unanticipated complications following pain interventions, thus providing safer care for their patients.

Cardiac Mapping

Cardiac Mapping
Author: Mohammad Shenasa,Gerhard Hindricks,David J. Callans,John M. Miller,Mark E. Josephson
Publsiher: John Wiley & Sons
Total Pages: 1304
Release: 2019-04-04
ISBN 10: 1119152623
ISBN 13: 9781119152620
Language: EN, FR, DE, ES & NL

Cardiac Mapping Book Review:

The expanded guide to cardiac mapping The effective diagnosis and treatment of heart disease may vitally depend upon accurate and detailed cardiac mapping. However, in an era of rapid technological advancement, medical professionals can encounter difficulties maintaining an up-to-date knowledge of current methods. This fifth edition of the much-admired Cardiac Mapping is, therefore, essential, offering a level of cutting-edge insight that is unmatched in its scope and depth. Featuring contributions from a global team of electrophysiologists, the book builds upon previous editions' comprehensive explanations of the mapping, imaging, and ablation of the heart. Nearly 100 chapters provide fascinating accounts of topics ranging from the mapping of supraventricular and ventriculararrhythmias, to compelling extrapolations of how the field might develop in the years to come. In this text, readers will find: Full coverage of all aspects of cardiac mapping, and imaging Explorations of mapping in experimental models of arrhythmias Examples of new catheter-based techniques Access to a companion website featuring additional content and illustrative video clips Cardiac Mapping is an indispensable resource for scientists, clinical electrophysiologists, cardiologists, and all physicians who care for patients with cardiac arrhythmias.

Consults in Obstetric Anesthesiology

Consults in Obstetric Anesthesiology
Author: Suzanne K. W. Mankowitz
Publsiher: Springer
Total Pages: 699
Release: 2018-11-15
ISBN 10: 3319596802
ISBN 13: 9783319596808
Language: EN, FR, DE, ES & NL

Consults in Obstetric Anesthesiology Book Review:

This text addresses the need for a book specifically aimed at obstetric anesthesia and covers topics such as pulmonary, cardiac renal, hepatic, hematologic, neurologic, endocrine and other diseases. The real anesthetic challenge arises when patients present to Labor and Delivery with unusual or complicated medical problems and, in recent years, a few of the larger institutions have developed an Obstetric Anesthesiology Consultation Service to prepare for the management of these patients. While most pregnant women who present to Labor and Delivery require anesthetic intervention, they typically meet the anesthesiologist for the first time in labor. Since the majority of laboring women are healthy without significant comorbidities, this does not present much of a challenge to the anesthesiologist and the anesthetic management tends to be straight-forward with favorable outcomes. However, using this new model, the anesthesiologist has the opportunity to discuss the various treatment modalities and potentially suggest diagnostic testing to be performed prior to delivery, similar to the pre-operative testing that is done in other surgical environments.

Field Guide to the Arrhythmias

Field Guide to the Arrhythmias
Author: Ellis Lader
Publsiher: John Wiley & Sons
Total Pages: 174
Release: 2013-05-06
ISBN 10: 1118386094
ISBN 13: 9781118386095
Language: EN, FR, DE, ES & NL

Field Guide to the Arrhythmias Book Review:

…The cardiac unit is a jungle, inhabited by fierce nurses, killer intensivists, marauding attendings, various flesh-eating specialists, sick patients, and lots of arrhythmias. –from the Preface Can you recognize the call of the normal sinus rhythm? Name the natural habitat of Multifocal Atrial Tachycardia or Ventricular Fibrillation? Are you well-versed in the proper care and feeding of Asystole and Atrial Flutter? If you answered “no” to any of these questions, then you need this trusty guide to help you identify and respond to arrhythmias in the veritable wilderness of the busy hospital ward. Created by a seasoned physician educator at a major urban medical center and inspired by the “field guides” used by birders, botanists and the like to identify flora or fauna in the wild, this new book offers a unique – and uniquely humorous -- approach to mastering the ever-vexing challenge of arrhythmia identification. Each arrhythmia is covered beginning with a sample ECG strip, followed by brief text describing its significant characteristics; where and when it is likely to be encountered (its “Habitat”); comments, questions and queries likely to be heard from physicians and other colleagues on the ward (the “Call”); and finally what steps the reader needs to take upon identifying the arrhythmia in a patient (“Care and Feeding”). Dr. Lader’s approach brings the sights and sounds of a modern hospital to life, enabling you to understand arrhythmia diagnosis and clinical response in context, and his offbeat, sometimes irreverent humor makes each detail memorable. Fifty self-assessment questions are included to help you master arrhythmia essentials and test your knowledge.

Ventricular Arrhythmias

Ventricular Arrhythmias
Author: John M. Miller
Publsiher: W B Saunders Company
Total Pages: 184
Release: 2008-07-01
ISBN 10: 9781416062752
ISBN 13: 1416062750
Language: EN, FR, DE, ES & NL

Ventricular Arrhythmias Book Review:

Ventricular arrhythmias cause most cases of sudden cardiac death, which is the leading cause of death in the US. This issue reviews the causes of arrhythmias and the promising new drugs and devices to treat arrhythmias.

Electrocardiogram in Clinical Medicine

Electrocardiogram in Clinical Medicine
Author: Michael J. Lipinski,Andrew E. Darby,Michael C. Bond,Nathan P. Charlton,Korin Hudson,Kelly Williamson
Publsiher: John Wiley & Sons
Total Pages: 512
Release: 2020-11-09
ISBN 10: 1118754557
ISBN 13: 9781118754559
Language: EN, FR, DE, ES & NL

Electrocardiogram in Clinical Medicine Book Review:

Offers a guide for a complete understanding of the disease and conditions most frequently revealed in ECGs recorded in the acute, critical, and emergency care settings Electrocardiogram in Clinical Medicine offers an authoritative guide to ECG interpretation that contains a focus and perspective from each of the three primary areas of medical care: acute care, critical care and emergency care. It can be used as a companion with the book ECGs for the Emergency Physician I & II (by Mattu and Brady) or as a stand-alone text. These three books can be described as a cumulative EGG reference for the medical provider who uses the electrocardiogram on a regular basis. Electrocardiogram in Clinical Medicine includes sections on all primary areas of ECG interpretation and application as well as sections that highlight use, devices and strategies. The medical content covers acute coronary syndromes and all related issues, other diseases of the myocardium, morphologic syndromes, toxicology and paediatrics; dysrhythmias will also be covered in detail. This important resource: • Goes beyond pattern recognition in ECGs to offer a real understanding of the clinical syndromes evidenced in ECGs and implications for treatment • Covers the indications, advantages and pitfalls of the use of ECGs for diagnosis in all acute care settings, from EMS to ED to Critical Care • Examines the ECG in toxic, metabolic and environmental presentations; critical information for acute care clinicians who need to be able to differentiate ODs, poisoning and other environmental causes from MI or other cardiac events • Facilitates clinical decision-making Written for practicing ER, general medicine, family practice, hospitalist and ICU physicians and medical students, Electrocardiogram in Clinical Medicine is an important book for the accurate interpretation of EGG results.

Diagnostic Molecular Pathology

Diagnostic Molecular Pathology
Author: William B. Coleman,Gregory J. Tsongalis
Publsiher: Academic Press
Total Pages: 582
Release: 2016-10-05
ISBN 10: 0128011572
ISBN 13: 9780128011577
Language: EN, FR, DE, ES & NL

Diagnostic Molecular Pathology Book Review:

Diagnostic Molecular Pathology: A Guide to Applied Molecular Testing is organized around disease types (genetic disease, infectious disease, neoplastic disease, among others). In each section, the authors provide background on disease mechanisms and describe how laboratory testing is built on knowledge of these mechanisms. Sections are dedicated to general methodologies employed in testing (to convey the concepts reflected in the methods), and specific description of how these methods can be applied and are applied to specific diseases are described. The book does not present molecular methods in isolation, but considers how other evidence (symptoms, radiology or other imaging, or other clinical tests) is used to guide the selection of molecular tests or how these other data are used in conjunction with molecular tests to make diagnoses (or otherwise contribute to clinical workup). In addition, final chapters look to the future (new technologies, new approaches) of applied molecular pathology and how discovery-based research will yield new and useful biomarkers and tests. Diagnostic Molecular Pathology: A Guide to Applied Molecular Testing contains exercises to test readers on their understanding of how molecular diagnostic tests are utilized and the value of the information that can be obtained in the context of the patient workup. Readers are directed to an ancillary website that contains supplementary materials in the form of exercises where decision trees can be employed to simulate actual clinical decisions. Focuses on the menu of molecular diagnostic tests available in modern molecular pathology or clinical laboratories that can be applied to disease detection, diagnosis, and classification in the clinical workup of a patient Explains how molecular tests are utilized to guide the treatment of patients in personalized medicine (guided therapies) and for prognostication of disease Features an ancillary website with self-testing exercises where decision trees can be employed to simulate actual clinical decisions Highlights new technologies and approaches of applied molecular pathology and how discovery-based research will yield new and useful biomarkers and tests

ECG Masters Collection Volume 2

ECG  Masters    Collection  Volume 2
Author: Mohammad Shenasa, MD,Mark E. Josephson, MD,N. A. Mark Estes III, MD,Ezra A. Amsterdam, MD,Melvin Scheinman, MD
Publsiher: Cardiotext Publishing
Total Pages: 216
Release: 2018-02-15
ISBN 10: 1942909217
ISBN 13: 9781942909217
Language: EN, FR, DE, ES & NL

ECG Masters Collection Volume 2 Book Review:

Over 75 exceptional electrocardiogram case studies curated from the libraries of 60 internationally recognized master teachers of ECG interpretation are brought together in this one-of-a-kind resource for student and teacher alike. Organized by disease type, ECG case studies are presented in a clinical context followed by questions and discussion. Medical students, residents, fellows, physicians — anyone who is involved in caring for patients with various cardiovascular diseases and other systemic pathologies — will find this unique collection with a global perspective useful and practical in developing the skills necessary to reading ECGs.

Electrocardiography ECG

Electrocardiography  ECG
Author: Jean-Jacques Goy,Jean-Christophe Stauffer,Jürg Schlaepfer,Pierre Christeler
Publsiher: Bentham Science Publishers
Total Pages: 159
Release: 2013-06-27
ISBN 10: 1608054799
ISBN 13: 9781608054794
Language: EN, FR, DE, ES & NL

Electrocardiography ECG Book Review:

This e-book starts with a comprehensive overview of the basic principles in Electrocardiography (ECG) with just enough depth to lift the reader above the crowd when it comes to understanding the physics behind ECG. Subsequent chapters provide an approach to the analysis of the ECG, followed by sections with insight into conduction abnormalities, arrhythmia, and myocardial ischemia. The e-book has a straightforward layout, a very clear format, and abundant ECG tracings for interested readers. The diagnostic algorithms provided in the volume prove to be very useful in daily medical practice. Overall, the e-book will help novice physicians, students and fellows to improve their knowledge in ECG interpretation. Electrocardiography (ECG) is, therefore, a very attractive book for all levels of physicians and health-care professionals interested in ECG and it is a welcome addition to the medical literature.

Electrical Diseases of the Heart

Electrical Diseases of the Heart
Author: Ihor Gussak,Charles Antzelevitch
Publsiher: Springer Science & Business Media
Total Pages: 600
Release: 2008-09-08
ISBN 10: 1846288541
ISBN 13: 9781846288548
Language: EN, FR, DE, ES & NL

Electrical Diseases of the Heart Book Review:

This book provides a unique contemporary and succinct distillation of the current status of recently delineated electrical diseases of the heart, emphasizing their common and diverse clinical features. The latest developments in the field of experimental and clinical cardiac electrophysiology, genetics, pharmacology and interventional therapies of various clinical arrhythmogenic entities are featured and discussed in terms of recent advances in basic and clinical science. The book is divided into seven major parts. Each part consists of chapters (total of 64) dealing with related topics.

Myocardial Repolarization From Gene to Bedside

Myocardial Repolarization  From Gene to Bedside
Author: Ali Oto,Gunter Breithardt
Publsiher: Wiley-Blackwell
Total Pages: 402
Release: 2001-12-10
ISBN 10: 9780879934774
ISBN 13: 0879934778
Language: EN, FR, DE, ES & NL

Myocardial Repolarization From Gene to Bedside Book Review:

A convenient guide of easily accessible information on the mechanisms of myocardial repolarization and related clinical issues. This book provides a unique collection of contributions by prominent cardiologists on the current knowledge of the mechanisms of arrhythmias, the molecular and genetic bases of noninvasive electrocardiologic diagnosis, and other related clinical issues. In addition to mechanistic aspects, recent developments in the diagnosis of arrhythmias using newly recognized markers (QT dispersion, T-wave alternans, etc.) and their clinical importance are addressed in an easily accessible manner by world-renowned authors. The book is a quick-reference for practicing cardiologists and electrophysiologists, those in training, and others who work in the field of arrhythmology.

Principles of Safety Pharmacology

Principles of Safety Pharmacology
Author: Michael K. Pugsley,Michael J Curtis
Publsiher: Springer
Total Pages: 481
Release: 2015-06-19
ISBN 10: 366246943X
ISBN 13: 9783662469439
Language: EN, FR, DE, ES & NL

Principles of Safety Pharmacology Book Review:

This book illustrates, in a comprehensive manner, the most current areas of importance to Safety Pharmacology, a burgeoning unique pharmacological discipline with important ties to academia, industry and regulatory authorities. It provides readers with a definitive collection of topics containing essential information on the latest industry guidelines and overviews current and breakthrough topics in both functional and molecular pharmacology. An additional novelty of the book is that it constitutes academic, pharmaceutical and biotechnology perspectives for Safety Pharmacology issues. Each chapter is written by an expert in the area and includes not only a fundamental background regarding the topic but also detailed descriptions of currently accepted, validated models and methods as well as innovative methodologies used in drug discovery.

Clin Alert 2001

Clin Alert 2001
Author: Joyce Generali
Publsiher: CRC Press
Total Pages: 270
Release: 2001-02-05
ISBN 10: 9781587160783
ISBN 13: 1587160781
Language: EN, FR, DE, ES & NL

Clin Alert 2001 Book Review:

Now the adverse drug reaction events reported in the newsletter Clin-Alert during Y2000 have been compiled, organized, re-formatted, indexed, and published in a convenient one-volume reference book, Clin-Alert 2001. The new book contains the full texts of all 311 reports from Clin-Alert newsletter 2000 issues. The reports have been grouped by fourteen major drug categories and indexed in six different ways for quick look-up. The reports were originally prepared for the Clin-Alert newsletter based on an ongoing search of more than 100 major medical journals, and summarization of key information included in journal articles on adverse drug reaction events. The summary reports were prepared by drug information specialists, and include the following information: o generic name of the drug or other substance involved o a brief characterization of the adverse reaction o a one paragraph summary of the event and related patient information o the author's conclusions or warnings o original source information Established in 1962, the Clin-Alert newsletter is a semi-monthly drug information service widely used by healthcare professionals involved in drug therapy and administration. It is independent, accepts no advertising, and is published for professional use. Now published, Clin-Alert 2001 provides an easy-to-use, quick and reliable reference that will be useful to healthcare professionals working with drugs.