Theory and Applications of Nonparenteral Nanomedicines

Theory and Applications of Nonparenteral Nanomedicines
Author: Prashant Kesharwani,Sebastien Taurin,Khaled Greish
Publsiher: Academic Press
Total Pages: 540
Release: 2020-09-12
ISBN 10: 0128204672
ISBN 13: 9780128204672
Language: EN, FR, DE, ES & NL

Theory and Applications of Nonparenteral Nanomedicines Book Review:

Theory and Applications of Nonparenteral Nanomedicines presents thoroughly analysed data and results regarding the potential of nanomedicines conceived by diverse non-parenteral routes. In the context of nanotechnology-based approaches, various routes such as oral, pulmonary, transdermal, delivery and local administration of nanomedicine have been utilized for the delivery of nanomedicine. This book discusses the non-parenteral application of nanomedicine, its regulatory implications, application of mucus penetrating nanocarrier, and detailed chapters on development of nanomedicines developed for drug delivery by various route. Beginning with a brief introduction to the non-parenteral delivery of nanomedicine and the safety and regulatory implications of the nanoformulations, further chapters discuss the physiology of the biological barriers, the specificity of the nanocarriers as well as their multiple applications. Theory and Applications of Nonparenteral Nanomedicines helps clinical researchers, researchers working in pharmaceutical industries, graduate students, and anyone working in the development of non-parenteral nanomedicines to understand the recent progress in the design and development of nanoformulations compatible with non-parenteral applications. Contains a comprehensive review of non-parenteral nanomedicines Provides analysis of non-parenteral methods of nanomedicines including regulatory implications and future applications Explores a wide range of promising approaches for non-parenteral drug delivery using the latest advancement in nanomedicine written by experts in industry and academia

Dendrimers in Nanomedicine

Dendrimers in Nanomedicine
Author: Neelesh Kumar Mehra,Keerti Jain
Publsiher: CRC Press
Total Pages: 314
Release: 2021-03-23
ISBN 10: 1000333035
ISBN 13: 9781000333039
Language: EN, FR, DE, ES & NL

Dendrimers in Nanomedicine Book Review:

Dendrimers, hyperbranched macromolecules, emerged just few decades ago but show promising potential as drug delivery nanocarriers, theranostic agents and gene vectors; in the pharmaceutical research and innovation area as well as in other healthcare applications. Although tremendous advancements have been made in dendrimer chemistry and their applications since their emergence, the synthesis, development and design of pure and safe dendrimer-based products have been a major challenge in this area. This book, edited by well-known researchers in the area of nanomaterials and drug-based drug delivery applications, exhaustively covers the nanotechnological aspects, concepts, properties, characterisation, application, biofate and regulatory aspects of dendrimers. It includes sixteen vivid chapters by renowned formulators, researchers and academicians from all over the world, highlighting their specialised areas of interest in the fields of chemistry, biology, pharmacy and nanomedicine. Features: • Highlights dendrimers’ advancements in nanomedicine in the development of safe healthcare and biotechnological products • Covers physicochemical aspects, biofate, drug delivery aspects and gene therapy using dendrimers • Covers biomedical application of dendrimers in the field of biological sciences • Gives examples of dendrimer–guest interaction chemistry Dendrimers in Nanomedicine: Concept, Theory and Regulatory Perspectives provides the comprehensive overview of the latest research efforts in designing, optimising, development and scale-up of dendrimer-mediated delivery systems. It analyses the key challenges of synthesis, design, molecular modelling, fundamental concepts, drug delivery aspects, analytical tools and biological fate as well as regulatory consideration to the practical use of dendrimer application. Dr. Neelesh Kumar Mehra Assistant Professor of Pharmaceutics in the Department of Pharmaceutics at the National Institute of Pharmaceutical Education & Research (NIPER), Hyderabad, India. He has authored more than sixty peer-reviewed publications in highly reputed international journals, as well as book chapters and contributions on two patents. Dr. Mehra has 11 years of rich research and teaching experience in the formulation and development of complex, innovative biopharmaceutical products including micro- and nanotechnologies for regulated markets. Dr. Keerti Jain Assistant Professor of Pharmaceutics in the Department of Pharmaceutics, NIPER, Raebareli, India. For more than 10 years, she has been actively engaged in formulation and development of nanomedicines. Dr. Jain has supervised masters and doctoral pharmaceutics students in their research works which have been published in high quality, good impact factor journals. She has also authored more than 60 international manuscripts in peer reviewed high impact journals. In 2019, she was awarded the prestigious ICMR-Amir Shakuntala Award.

Nanotechnology Based Approaches for Tuberculosis Treatment

Nanotechnology Based Approaches for Tuberculosis Treatment
Author: Prashant Kesharwani
Publsiher: Academic Press
Total Pages: 284
Release: 2020-06-10
ISBN 10: 0128226110
ISBN 13: 9780128226117
Language: EN, FR, DE, ES & NL

Nanotechnology Based Approaches for Tuberculosis Treatment Book Review:

Nanotechnology Based Approaches for Tuberculosis Treatment discusses multiple nanotechnology-based approaches that may help overcome persisting limitations of conventional and traditional treatments. The book summarizes the types of nano drugs, their synthesis, formulation, characterization and applications, along with the most important administration routes. It also explores recent advances and achievements regarding therapeutic efficacy and provides possible future applications in this field. It will be a useful resource for investigators, pharmaceutical researchers, innovators and scientists working on technology advancements in the areas of targeted therapies, nano scale imaging systems, and diagnostic modalities in tuberculosis. Addresses the gap between nanomedicine late discovery and early development of tuberculosis therapeutics Explores tuberculosis nanomedicine standardization and characterization with newly developed treatment, diagnostic and treatment monitoring modalities Covers the field thoroughly, from the pathogenesis of tuberculosis and multi-drug resistant mycobacterium tuberculosis, to treatment approaches using nanotechnology and different nanocarriers

Application of Nanotechnology in Drug Delivery

Application of Nanotechnology in Drug Delivery
Author: Ali Demir Sezer
Publsiher: BoD – Books on Demand
Total Pages: 554
Release: 2014-07-25
ISBN 10: 9535116282
ISBN 13: 9789535116288
Language: EN, FR, DE, ES & NL

Application of Nanotechnology in Drug Delivery Book Review:

This book collects reviews and original articles from eminent experts working in the interdisciplinary arena of nanotechnology use in drug delivery. From their direct and recent experience, the readers can achieve a wide vision on the new and ongoing potentialities of nanotechnology application of drug delivery. Since the advent of analytical techniques and capabilities to measure particle sizes in nanometer ranges, there has been tremendous interest in the use of nanoparticles for more efficient methods of drug delivery. On the other hand, this reference discusses advances in design, optimization, and adaptation of gene delivery systems for the treatment of cancer, cardiovascular, pulmonary, genetic, and infectious diseases, and considers assessment and review procedures involved in the development of gene-based pharmaceuticals.

Unit Operations II

Unit Operations II
Author: Ka Gavhane
Publsiher: Nirali Prakashan
Total Pages: 470
Release: 2014-11
ISBN 10: 9788196396121
ISBN 13: 8196396120
Language: EN, FR, DE, ES & NL

Unit Operations II Book Review:

Introduction - Conduction - Convection - Radiation - Heat Exchange Equipments - Evaporation - Diffusion - Distillation - Gas Absorption - Liquid Liquid Extraction - Crystallisation - Drying - Appendix I Try yourself - Appendix II Thermal conductivity data - Appendix III Steam tables

Surface Modification of Nanoparticles for Targeted Drug Delivery

Surface Modification of Nanoparticles for Targeted Drug Delivery
Author: Yashwant V Pathak
Publsiher: Springer
Total Pages: 499
Release: 2019-03-11
ISBN 10: 3030061159
ISBN 13: 9783030061159
Language: EN, FR, DE, ES & NL

Surface Modification of Nanoparticles for Targeted Drug Delivery Book Review:

This unique book is the only one to discuss various new techniques developed to enhance the application of nanoparticulate drug delivery systems using surface modification of nanoparticles. The understanding of the surface characteristics nano-particles is growing significantly with the advent of new analytical techniques. Polymer chemistry is contributing to the development of many new versatile polymers which have abilities to accommodate many different, very reactive chemical groups, and can be used as a diagnostic tool, for better targeting, for more effective therapeutic results as well as for reducing the toxic and side effects of the drugs. Surface modification of such polymeric nanoparticles has been found by many scientists to enhance the application of nanoparticles and also allows the nano particles to carry specific drug molecule and disease /tumor specific antibodies which refine and improve drug delivery. Surface Modification of Nanoparticles for Targeted Drug Delivery is a collection essential information with various applications of surface modification of nanoparticles and their disease specific applications for therapeutic purposes.

Nanomedicine and Cancer Therapies

Nanomedicine and Cancer Therapies
Author: Mathew Sebastian,Neethu Ninan,Eldho Elias
Publsiher: CRC Press
Total Pages: 250
Release: 2012-07-27
ISBN 10: 1926895185
ISBN 13: 9781926895185
Language: EN, FR, DE, ES & NL

Nanomedicine and Cancer Therapies Book Review:

Nanotechnology has the power to radically change the way cancer is diagnosed, imaged, and treated. The holistic approach to cancer involves noninvasive procedures that emphasize restoring the health of human energy fields. Presenting a wealth of information and research about the most potent cancer healing therapies, this forward-thinking book explores how nanomedicine, holistic medicine, and other cancer therapies play important roles in treatment of this disease. Topics include nanobiotechnology for antibacterial therapy and diagnosis, mitochondrial dysfunction and cancer, antioxidants and combinatorial therapies, and optical and mechanical investigations of nanostructures for biomolecular detection.

Nanoparticle Vaccines Against Infectious Diseases

Nanoparticle Vaccines Against Infectious Diseases
Author: Rajko Reljic,África González-Fernández
Publsiher: Frontiers Media SA
Total Pages: 329
Release: 2020-01-15
ISBN 10: 2889633276
ISBN 13: 9782889633272
Language: EN, FR, DE, ES & NL

Nanoparticle Vaccines Against Infectious Diseases Book Review:

Single Chain Polymer Nanoparticles

Single Chain Polymer Nanoparticles
Author: José A. Pomposo
Publsiher: John Wiley & Sons
Total Pages: 312
Release: 2017-08-18
ISBN 10: 3527806393
ISBN 13: 9783527806393
Language: EN, FR, DE, ES & NL

Single Chain Polymer Nanoparticles Book Review:

This first book on this important and emerging topic presents an overview of the very latest results obtained in single-chain polymer nanoparticles obtained by folding synthetic single polymer chains, painting a complete picture from synthesis via characterization to everyday applications. The initial chapters describe the synthetics methods as well as the molecular simulation of these nanoparticles, while subsequent chapters discuss the analytical techniques that are applied to characterize them, including size and structural characterization as well as scattering techniques. The final chapters are then devoted to the practical applications in nanomedicine, sensing, catalysis and several other uses, concluding with a look at the future for such nanoparticles. Essential reading for polymer and materials scientists, materials engineers, biochemists as well as environmental chemists.

Introduction to Basics of Pharmacology and Toxicology

Introduction to Basics of Pharmacology and Toxicology
Author: Gerard Marshall Raj,Ramasamy Raveendran
Publsiher: Springer Nature
Total Pages: 417
Release: 2019-11-16
ISBN 10: 9813297794
ISBN 13: 9789813297791
Language: EN, FR, DE, ES & NL

Introduction to Basics of Pharmacology and Toxicology Book Review:

This book illustrates, in a comprehensive manner, the most crucial principles involved in pharmacology and allied sciences. The title begins by discussing the historical aspects of drug discovery, with up to date knowledge on Nobel Laureates in pharmacology and their significant discoveries. It then examines the general pharmacological principles - pharmacokinetics and pharmacodynamics, with in-depth information on drug transporters and interactions. In the remaining chapters, the book covers a definitive collection of topics containing essential information on the basic principles of pharmacology and how they are employed for the treatment of diseases. Readers will learn about special topics in pharmacology that are hard to find elsewhere, including issues related to environmental toxicology and the latest information on drug poisoning and treatment, analytical toxicology, toxicovigilance, and the use of molecular biology techniques in pharmacology. The book offers a valuable resource for researchers in the fields of pharmacology and toxicology, as well as students pursuing a degree in or with an interest in pharmacology.

Nanomedicine and Drug Delivery

Nanomedicine and Drug Delivery
Author: Mathew Sebastian,Neethu Ninan,A. K. Haghi
Publsiher: CRC Press
Total Pages: 270
Release: 2012-07-23
ISBN 10: 1926895177
ISBN 13: 9781926895178
Language: EN, FR, DE, ES & NL

Nanomedicine and Drug Delivery Book Review:

This forward-looking book focuses on the recent advances in nanomedicine and drug delivery. It outlines the extraordinary new tools that have become available in nanomedicine and presents an integrated set of perspectives that describe where we are now and where we should be headed to put nanomedicine devices into applications as quickly as possible, while also considering the possible dangers of nanomedicine. The book considers the full range of nanomedicinal applications that employ molecular nanotechnology inside the human body, from the perspective of a future practitioner in an era of widely available nanomedicine. Written by some of the most innnovative minds in medicine and engineering, this unique volume will help professionals understand cutting-edge and futuristic areas of research that can have tremendous payoff in terms of improving human health. Readers will find insightful discussions of nanostructured intelligent materials and devices that are considered technically feasible and which have a high potential to produce advances in medicine in the near future. Topics include: Health benefits of phytochemicals and the application of colloidal delivery systems Study of non-covalent attachment of recombinant targeting proteins to polymer-modified Adenoviral gene delivery vectors The role of nanoparticles as adjuvants for mucosal vaccine delivery Poly(amido-amine)s as delivery styems for biologically active substances Antimicrobial activity of silver nanoparticles Nanomedicine in the use of cancer treatment Dendrimers, capsules based on lipid vesicles for drug delivery Many other recent achievements

Ocular Drug Delivery Advances Challenges and Applications

Ocular Drug Delivery  Advances  Challenges and Applications
Author: Richard T. Addo
Publsiher: Springer
Total Pages: 185
Release: 2016-11-16
ISBN 10: 3319476912
ISBN 13: 9783319476919
Language: EN, FR, DE, ES & NL

Ocular Drug Delivery Advances Challenges and Applications Book Review:

The eye is a computerized system that has been designed for self-defense, and these defense mechanisms create challenges in administration of medications to the eye. Therefore, ocular drug delivery has been a major challenge to drug delivery researchers. There are on-going studies, in search of treatment especially for the diseases affecting the posterior segment of the eye. This book gives and overview of the background of ocular drug delivery and is unique for pharmacists, medical practitioners, students and drug delivery researchers.

Pharmacokinetics and Drug Metabolism in Canada The Current Landscape

Pharmacokinetics and Drug Metabolism in Canada  The Current Landscape
Author: Neal M. Davies,Kishor M. Wasan
Publsiher: MDPI
Total Pages: 329
Release: 2018-03-23
ISBN 10: 3038427977
ISBN 13: 9783038427971
Language: EN, FR, DE, ES & NL

Pharmacokinetics and Drug Metabolism in Canada The Current Landscape Book Review:

This book is a printed edition of the Special Issue "Pharmacokinetics and Drug Metabolism in Canada: The Current Landscape" that was published in Pharmaceutics

Mucosal Delivery of Drugs and Biologics in Nanoparticles

Mucosal Delivery of Drugs and Biologics in Nanoparticles
Author: Pavan Muttil,Nitesh K. Kunda
Publsiher: Springer Nature
Total Pages: 277
Release: 2020-03-18
ISBN 10: 3030359107
ISBN 13: 9783030359102
Language: EN, FR, DE, ES & NL

Mucosal Delivery of Drugs and Biologics in Nanoparticles Book Review:

Nanotechnology has revolutionized the approach to designing and developing novel drug delivery systems. The last two decades have seen a great interest in the use of nanotechnology to offer efficient ways of delivering new and existing drugs and macromolecules. The focus of this book is the application of nanotechnology to deliver drugs and biological agents by the mucosal routes of administration i.e. nasal, pulmonary, buccal, and oral routes. It provides an overview of nanotechnology in drug delivery with a description of different types of nanoparticles, methods of preparation and characterization, and functionalization for site-specific drug delivery. The emphasis is on the use of nanoparticles in treating various cancers and infectious diseases. It broadens the use of nanoparticles by including biologics, including vaccines and immunotherapies, apart from drugs and acknowledges the concerns around the potential toxicity of nanoparticles to the host; several chapters will discuss the biodistribution of these nanoparticles when mucosal routes of administration are employed. Further, the interaction of nanoparticles with the host’s immune cells is discussed. Moreover, it reviews the regulatory aspects of nanotechnology in product development, especially when delivered by the mucosal route of administration. Lastly, discusses the challenges and opportunities to manufacture nanoparticles on an industrial scale. This book is the first of its kind to focus on the design, development and delivery of nanoparticles when administered by different mucosal routes.

Nanoparticles in Life Sciences and Biomedicine

Nanoparticles in Life Sciences and Biomedicine
Author: Ana Rute Neves,Salette Reis
Publsiher: CRC Press
Total Pages: 552
Release: 2018-02-13
ISBN 10: 1351207342
ISBN 13: 9781351207348
Language: EN, FR, DE, ES & NL

Nanoparticles in Life Sciences and Biomedicine Book Review:

The creation of new and more efficient therapies for improving human health greatly depends on drug delivery systems. Nanotechnology has emerged as a powerful strategy for the development of nanoparticles, such as nanoemulsions, liposomes, nanocrystals, and nanocomplexes, applied in the diagnosis, treatment, or theranostics of several pathologies and diseases. This book reviews the most recent research and development in nanotechnology and, following a multidisciplinary approach, presents new strategies for drug delivery, including aspects from chemistry, physics, biology, and imaging methodologies and exploiting several administration routes, internalization pathways, site-specific delivery strategies, and the potential cytotoxicity of nanoparticles. Beginning with a description of the importance and application of nanotechnology for enhancing existing therapy, the book moves on to detailing oral, topical, pulmonary, brain, cancer, and anti-inflammatory drug delivery approaches; gene delivery approaches; theranostic approaches; and nanoparticle cytotoxicity. Practical and user friendly, it is suitable for advanced undergraduate, graduate, and postgraduate students of nanoscience and nanotechnology; researchers in nanoscience, nanotechnology, chemistry, biology, biochemistry, pharmaceutical sciences, medicine, and bioengineering, especially those with an interest in drug delivery or theranostics; and academia and university readership.

Biotechnology and Biopharmaceuticals

Biotechnology and Biopharmaceuticals
Author: Anonim
Publsiher: John Wiley & Sons
Total Pages: 744
Release: 2013-12-16
ISBN 10: 111817979X
ISBN 13: 9781118179796
Language: EN, FR, DE, ES & NL

Biotechnology and Biopharmaceuticals Book Review:

Biotechnology and Biopharmaceuticals: Transforming Proteins and Genes into Drugs, Second Edition addresses the pivotal issues relating to translational science, including preclinical and clinical drug development, regulatory science, pharmaco-economics and cost-effectiveness considerations. The new edition also provides an update on new proteins and genetic medicines, the translational and integrated sciences that continue to fuel the innovations in medicine, as well as the new areas of therapeutic development including cancer vaccines, stem cell therapeutics, and cell-based therapies.

Therapeutic Peptides and Proteins

Therapeutic Peptides and Proteins
Author: Ajay K. Banga
Publsiher: CRC Press
Total Pages: 376
Release: 2005-09-14
ISBN 10: 1420039830
ISBN 13: 9781420039832
Language: EN, FR, DE, ES & NL

Therapeutic Peptides and Proteins Book Review:

Upon publication of the first edition of Therapeutic Peptides and Proteins ten years ago there were only 19 biotechology medicines on the market. Currently there are more than 100, with at least 400 more in various stages of development. That alone would be grounds for a new edition. Add to that the fact that it is still difficult to find up

ADME Processes in Pharmaceutical Sciences

ADME Processes in Pharmaceutical Sciences
Author: Alan Talevi,Pablo A. M. Quiroga
Publsiher: Springer
Total Pages: 362
Release: 2018-11-30
ISBN 10: 3319995936
ISBN 13: 9783319995939
Language: EN, FR, DE, ES & NL

ADME Processes in Pharmaceutical Sciences Book Review:

Absorption, Distribution, Metabolism and Excretion (ADME) processes and their relationship with the design of dosage forms and the success of pharmacotherapy form the basis of this upper level undergraduate/graduate textbook. As an introduction oriented to pharmacy students, it is also written for scientist from different fields outside of pharmaceutics. (e.g. material scientist, material engineers, medicinal chemists) who might be working in a positions in pharmaceutical companies or whose work might benefit from basic training in the ADME concepts and some biological background. Pedagogical features such as objectives, keywords, discussion questions, summaries and case studies add valuable teaching tools. This book will provide not only general knowledge on ADME processes but also an updated insight on some hot topics such as drug transporters, multi-drug resistance related to pharmacokinetic phenomena, last generation pharmaceutical carriers (nanopharmaceuticals), in vitro and in vivo bioequivalence studies, biopharmaceuticals, pharmacogenomics, drug-drug and food-drug interactions, and in silico and in vitro prediction of ADME properties. In comparison with other similar textbooks, around half of the volume would be focused on the relationship between expanding scientific fields and ADME processes. Each of these burgeoning fields has a separate chapter in the second part of the volume, and was written with leading experts on the correspondent topic, including scientists and academics from USA and UK (Duquesne University School of Pharmacy, Indiana University School of Medicine, University of Utah College of Pharmacy, University of Maryland, University of Bath). Additionally, each of the initial chapters dealing with the generalities of drug absorption, distribution, metabolism and excretion would include relevant, classic examples related to each topic with appropriate illustrations (e.g. importance of active absorption of levodopa, implications in levodopa administration, drug drug interactions and food drug interactions emerging from the active uptake; intoxication with paracetamol as a result of glutathione depletion, CYP induction and its relationship with acute liver failure caused by paracetamol, etc). ADME Processes and Pharmaceutical Sciences is written as a core textbook for ADME processes, pharmacy, pharmacokinetics, drug delivery, biopharmaceutics, drug disposition, drug design and medicinal chemistry courses.

Fine Particles in Medicine and Pharmacy

Fine Particles in Medicine and Pharmacy
Author: Egon Matijević
Publsiher: Springer Science & Business Media
Total Pages: 348
Release: 2011-09-18
ISBN 10: 9781461403791
ISBN 13: 1461403790
Language: EN, FR, DE, ES & NL

Fine Particles in Medicine and Pharmacy Book Review:

Pharmaceutical manufacture is very exacting – for example, drugs must be uniform in size, shape, efficacy, bioavailability, and safety. The presence of different polymorphs in drug production is a serious problem, since different polymorphs differ in bioavailability, solubility, dissolution rate, chemical and physical stability, melting point, color, filterability, density, and flow properties. Fine Particles in Medicine and Pharmacy discusses particle size, shape, and composition and how they determine the choice of polymorph of a drug.

Pharmaceutical Suspensions

Pharmaceutical Suspensions
Author: Alok K. Kulshreshtha,Onkar N. Singh,G. Michael Wall
Publsiher: Springer Science & Business Media
Total Pages: 327
Release: 2009-11-05
ISBN 10: 9781441910875
ISBN 13: 1441910875
Language: EN, FR, DE, ES & NL

Pharmaceutical Suspensions Book Review:

The suspension dosage form has long been used for poorly soluble active ingre- ents for various therapeutic indications. Development of stable suspensions over the shelf life of the drug product continues to be a challenge on many fronts. A good understanding of the fundamentals of disperse systems is essential in the development of a suitable pharmaceutical suspension. The development of a s- pension dosage form follows a very complicated path. The selection of the proper excipients (surfactants, viscosity imparting agents etc.) is important. The particle size distribution in the finished drug product dosage form is a critical parameter that significantly impacts the bioavailability and pharmacokinetics of the product. Appropriate analytical methodologies and instruments (chromatographs, visco- ters, particle size analyzers, etc.) must be utilized to properly characterize the s- pension formulation. The development process continues with a successful scale-up of the manufacturing process. Regulatory agencies around the world require cli- cal trials to establish the safety and efficacy of the drug product. All of this devel- ment work should culminate into a regulatory filing in accordance with the regulatory guidelines. Pharmaceutical Suspensions, From Formulation Development to Manufacturing, in its organization, follows the development approach used widely in the pharmaceutical industry. The primary focus of this book is on the classical disperse system – poorly soluble active pharmaceutical ingredients s- pended in a suitable vehicle.