The Science Etiology and Mechanobiology of Diabetes and its Complications

The Science  Etiology and Mechanobiology of Diabetes and its Complications
Author: Amit Gefen
Publsiher: Academic Press
Total Pages: 400
Release: 2021-02-01
ISBN 10: 0128210710
ISBN 13: 9780128210710
Language: EN, FR, DE, ES & NL

The Science Etiology and Mechanobiology of Diabetes and its Complications Book Review:

The Science, Etiology and Mechanobiology of Diabetes and its Complications presents the most comprehensive synthesis of contemporary global research on diabetes, covering a novel and unique mechanobiological perspective – addressing prevention, management and treatment of tissue, organ and body system damage associated with diabetes and its complications. The book provides a unique approach to communicating diabetes-associated symptoms and opens avenues for development of novel therapeutic and preventive methods. It offers descriptive pathophysiology of diabetes and its complications with great emphasis on mechanobiology. Content coverage also includes management of tissue, organ and body system damage caused by chronic hyperglycemia. Biologists, life scientists, physicians, pharmacists, biomedical engineers, medical physicists, biomathematicians and computer scientists who are interested in the state-of-science and current challenges in the mechanobiology of diabetes should find this book very useful. Likewise, medical researchers in fields such as endocrinology, cardiovascular medicine, oncology, obesity, the immune system, inflammation and wound care and others who wish to be updated about the latest achievements in this exciting arena of research will find that information here. Covers the state-of-knowledge in diabetes research from a mechanobiological perspective, including cell death and (neural, connective, adipose, vascular, renal etc.) tissue damage cascades and healing processes Describes state-of-the-art technology in prevention, diagnosis, prognosis and treatment of tissue, organ and body system damage caused by chronic hyperglycemia and diabetes Explores emerging research directions and future technology trends in the field of diabetes prevention and care, including common complications of diabetes (foot ulcers and amputation, peripheral neuropathy, retinal damage, renal damage, vascular and cardiac damage, connective tissue damage etc.) at the early stage of research and development in academia and industry

Mercer s Textbook of Orthopaedics and Trauma Tenth edition

Mercer s Textbook of Orthopaedics and Trauma Tenth edition
Author: Suresh Sivananthan,Eugene Sherry,Patrick Warnke,Mark Miller
Publsiher: CRC Press
Total Pages: 1620
Release: 2012-02-24
ISBN 10: 1444128760
ISBN 13: 9781444128765
Language: EN, FR, DE, ES & NL

Mercer s Textbook of Orthopaedics and Trauma Tenth edition Book Review:

Highly Commended, BMA Medical Book Awards 2013Orthopaedic problems account for over one-third of all medical and surgical problems. Mercer's Textbook of Orthopaedics and Trauma provides all the information required by the senior trainee or qualified specialist to improve understanding and management of any given condition or disease in this area.Si

Pathobiology of Human Disease

Pathobiology of Human Disease
Author: Anonim
Publsiher: Elsevier
Total Pages: 5000
Release: 2014-08-01
ISBN 10: 0123864577
ISBN 13: 9780123864574
Language: EN, FR, DE, ES & NL

Pathobiology of Human Disease Book Review:

Pathobiology of Human Disease bridges traditional morphologic and clinical pathology, molecular pathology, and the underlying basic science fields of cell biology, genetics, and molecular biology, which have opened up a new era of research in pathology and underlie the molecular basis of human disease. The work spans more than 48 different biological and medical fields, in five basic sections: Human Organ Systems Molecular Pathology/Basic Mechanisms of Diseases Animal Models/Other Model Systems Experimental Pathology Clinical Pathology Each article provides a comprehensive overview of the selected topic to inform a broad spectrum of readers from research professionals to advanced undergraduate students. Reviews quantitative advances in the imaging and molecular analysis of human tissue, new microarray technologies for analysis of genetic and chromosomal alterations in normal and diseased cells and tissues, and new transgenic models of human disease using conditional, tissue-specific gene targeting Articles link through to relevant virtual microscopy slides, illustrating side-by-side presentation of "Normal" and "Disease" anatomy and histology images Fully-annotated with many supplementary full color images, graphs, tables, and video files linked to data sets and to live references, enabling researchers to delve deeper and visualize solutions

Principles of Tissue Engineering

Principles of Tissue Engineering
Author: Robert Lanza,Robert Langer,Joseph P. Vacanti
Publsiher: Elsevier
Total Pages: 995
Release: 2000-05-16
ISBN 10: 008053967X
ISBN 13: 9780080539676
Language: EN, FR, DE, ES & NL

Principles of Tissue Engineering Book Review:

The opportunity that tissue engineering provides for medicine is extraordinary. In the United States alone, over half-a-trillion dollars are spent each year to care for patients who suffer from tissue loss or dysfunction. Although numerous books and reviews have been written on tissue engineering, none has been as comprehensive in its defining of the field. Principles of Tissue Engineering combines in one volume the prerequisites for a general understanding of tissue growth and development, the tools and theoretical information needed to design tissues and organs, as well as a presentation of applications of tissue engineering to diseases affecting specific organ systems. The first edition of the book, published in 1997, is the definite reference in the field. Since that time, however, the discipline has grown tremendously, and few experts would have been able to predict the explosion in our knowledge of gene expression, cell growth and differentiation, the variety of stem cells, new polymers and materials that are now available, or even the successful introduction of the first tissue-engineered products into the marketplace. There was a need for a new edition, and this need has been met with a product that defines and captures the sense of excitement, understanding and anticipation that has followed from the evolution of this fascinating and important field. Key Features * Provides vast, detailed analysis of research on all of the major systems of the human body, e.g., skin, muscle, cardiovascular, hematopoietic, and nerves * Essential to anyone working in the field * Educates and directs both the novice and advanced researcher * Provides vast, detailed analysis of research with all of the major systems of the human body, e.g. skin, muscle, cardiovascular, hematopoietic, and nerves * Has new chapters written by leaders in the latest areas of research, such as fetal tissue engineering and the universal cell * Considered the definitive reference in the field * List of contributors reads like a "who's who" of tissue engineering, and includes Robert Langer, Joseph Vacanti, Charles Vacanti, Robert Nerem, A. Hari Reddi, Gail Naughton, George Whitesides, Doug Lauffenburger, and Eugene Bell, among others

Principles of Regenerative Medicine

Principles of Regenerative Medicine
Author: Anthony Atala,Robert Lanza,James A. Thomson,Robert Nerem
Publsiher: Academic Press
Total Pages: 1202
Release: 2010-12-16
ISBN 10: 9780123814234
ISBN 13: 0123814235
Language: EN, FR, DE, ES & NL

Principles of Regenerative Medicine Book Review:

Virtually any disease that results from malfunctioning, damaged, or failing tissues may be potentially cured through regenerative medicine therapies, by either regenerating the damaged tissues in vivo, or by growing the tissues and organs in vitro and implanting them into the patient. Principles of Regenerative Medicine discusses the latest advances in technology and medicine for replacing tissues and organs damaged by disease and of developing therapies for previously untreatable conditions, such as diabetes, heart disease, liver disease, and renal failure. Key for all researchers and instituions in Stem Cell Biology, Bioengineering, and Developmental Biology The first of its kind to offer an advanced understanding of the latest technologies in regenerative medicine New discoveries from leading researchers on restoration of diseased tissues and organs

Mechanobiology

Mechanobiology
Author: Simon C. F. Rawlinson
Publsiher: John Wiley & Sons
Total Pages: 432
Release: 2017-01-31
ISBN 10: 1118966155
ISBN 13: 9781118966150
Language: EN, FR, DE, ES & NL

Mechanobiology Book Review:

An emerging field at the interface of biology and engineering, mechanobiology explores the mechanisms by which cells sense and respond to mechanical signals—and holds great promise in one day unravelling the mysteries of cellular and extracellular matrix mechanics to cure a broad range of diseases. Mechanobiology: Exploitation for Medical Benefit presents a comprehensive overview of principles of mechanobiology, highlighting the extent to which biological tissues are exposed to the mechanical environment, demonstrating the importance of the mechanical environment in living systems, and critically reviewing the latest experimental procedures in this emerging field. Featuring contributions from several top experts in the field, chapters begin with an introduction to fundamental mechanobiological principles; and then proceed to explore the relationship of this extensive force in nature to tissues of musculoskeletal systems, heart and lung vasculature, the kidney glomerulus, and cutaneous tissues. Examples of some current experimental models are presented conveying relevant aspects of mechanobiology, highlighting emerging trends and promising avenues of research in the development of innovative therapies. Timely and important, Mechanobiology: Exploitation for Medical Benefit offers illuminating insights into an emerging field that has the potential to revolutionise our comprehension of appropriate cell biology and the future of biomedical research.

Diabetes Mellitus

Diabetes Mellitus
Author: Derek LeRoith,Simeon I. Taylor,Jerrold M. Olefsky
Publsiher: Lippincott Williams & Wilkins
Total Pages: 1540
Release: 2004
ISBN 10: 9780781740975
ISBN 13: 0781740975
Language: EN, FR, DE, ES & NL

Diabetes Mellitus Book Review:

Thoroughly revised and updated, this Third Edition encompasses the most recent advances in molecular and cellular research and describes the newest therapeutic modalities for type 1 and type 2 diabetes mellitus. Chapters by leading experts integrate the latest basic science and clinical research on diabetes mellitus and its complications. The text is divided into ten major sections, including extensive sections on therapeutics, diabetes during pregnancy, and complications. New chapters cover stem cell therapy for type 1 diabetes; genetics and treatment of obesity; new therapies to promote insulin action; vasculopathy; islet cell protocols; triglycerides in muscle; hypoglycemia in the adult; and the Diabetes Prevention Program.

Regenerative Medicine Applications in Organ Transplantation

Regenerative Medicine Applications in Organ Transplantation
Author: Giuseppe Orlando
Publsiher: Academic Press
Total Pages: 1050
Release: 2013-10-11
ISBN 10: 012398520X
ISBN 13: 9780123985200
Language: EN, FR, DE, ES & NL

Regenerative Medicine Applications in Organ Transplantation Book Review:

Regenerative Medicine Applications in Organ Transplantation illustrates exactly how these two fields are coming together and can benefit one another. It discusses technologies being developed, methods being implemented, and which of these are the most promising. The text encompasses tissue engineering, biomaterial sciences, stem cell biology, and developmental biology, all from a transplant perspective. Organ systems considered include liver, renal, intestinal, pancreatic, and more. Leaders from both fields have contributed chapters, clearly illustrating that regenerative medicine and solid organ transplantation speak the same language and that both aim for similar medical outcomes. The overall theme of the book is to provide insight into the synergy between organ transplantation and regenerative medicine. Recent groundbreaking achievements in regenerative medicine have received unprecedented coverage by the media, fueling interest and enthusiasm in transplant clinicians and researchers. Regenerative medicine is changing the premise of solid organ transplantation, requiring transplantation investigators to become familiar with regenerative medicine investigations that can be extremely relevant to their work. Similarly, regenerative medicine investigators need to be aware of the needs of the transplant field to bring these two fields together for greater results. Bridges the gap between regenerative medicine and solid organ transplantation and highlights reasons for collaboration Explains the importance and future potential of regenerative medicine to the transplant community Illustrates to regenerative medicine investigators the needs of the transplant discipline to drive and guide investigations in the most promising directions

Metabolic Influences on Risk for Tendon Disorders

Metabolic Influences on Risk for Tendon Disorders
Author: Paul W. Ackermann,David A. Hart
Publsiher: Springer
Total Pages: 304
Release: 2016-08-17
ISBN 10: 3319339435
ISBN 13: 9783319339436
Language: EN, FR, DE, ES & NL

Metabolic Influences on Risk for Tendon Disorders Book Review:

This book will be of considerable interest to students, practitioners (Doctors, Physiotherapists, and other health care professionals), and researchers who deal with the complex structure of tendons and the need to effectively address tendon disorders. The book is divided into three sections: (1) Basic Biology and Biochemical Markers; (2) Metabolic Disorders; and (3) Novel Therapies. The first section, devoted to the basic biology of tendons, is aimed at those individuals who want to gain basic information on tendons and the subsection on biochemical markers is chiefly aimed at researchers who are developing new studies within this field. The section on metabolic disorders is mainly directed at practitioners who desire to know how metabolic disorders can affect tendons in order to optimize treatment for their patients. Finally, the section on novel therapies is focused on some new treatment options within this field, and discussions regarding how management of tendon disorders needs to incorporate perspectives on current understanding of tendon metabolism.

Multi scale Extracellular Matrix Mechanics and Mechanobiology

Multi scale Extracellular Matrix Mechanics and Mechanobiology
Author: Yanhang Zhang
Publsiher: Springer
Total Pages: 392
Release: 2019-07-12
ISBN 10: 3030201821
ISBN 13: 9783030201821
Language: EN, FR, DE, ES & NL

Multi scale Extracellular Matrix Mechanics and Mechanobiology Book Review:

This book describes the current state of knowledge in the field of multi-scale ECM mechanics and mechanobiology with a focus on experimental and modelling studies in biomechanical characterization, advanced optical microscopy and imaging, as well as computational modeling. This book also discusses the scale dependency of ECM mechanics, translation of mechanical forces from tissue to cellular level, and advances and challenges in improving our understanding of cellular mechanotransduction in the context of living tissues and organisms.

Osteoporosis

Osteoporosis
Author: Robert Marcus,David Feldman,Dorothy Nelson,Clifford Rosen
Publsiher: Academic Press
Total Pages: 2016
Release: 2007-11-08
ISBN 10: 9780080553474
ISBN 13: 0080553478
Language: EN, FR, DE, ES & NL

Osteoporosis Book Review:

Now in its third edition, Osteoporosis, is the most comprehensive, authoritative reference on this disease. Written by renowned experts in the field, this two-volume reference is a must-have for academic and medical libraries, physicians, researchers, and any company involved in osteoporosis research and development. Worldwide, 200 million women between 60-80 suffer from osteoporosis and have a lifetime risk of fracture between 30 and 40 percent continuing to make osteoporosis a hot topic in medicine. This newest edition covers everything from basic anatomy and physiology to diagnosis, management and treatment in a field where direct care costs for osteoporitic fractures in the U.S. reach up to $18 billion each year. NEW TO THIS EDITION: *Recognizes the critical importance of the Wnt signaling pathway for bone health *Incorporates new chapters on osteocytes, phosphatonins, mouse genetics, and CNS and bone *Examines essential updates on estrogen prevention and treatment and the recent results from the WHI *Discusses the controversial topics of screening and clinical trial design for drug registration *Includes essential updates on therapeutic uses of calcium, vitamin D, SERMS, bisphosphonates, and parathyroid hormone * Offers critical reviews of reproductive and hormonal risk factors, ethnicity, nutrition, therapeutics, management, and economics comprising a tremendous wealth of knowledge in a single source not found elsewhere

Innovations and Emerging Technologies in Wound Care

Innovations and Emerging Technologies in Wound Care
Author: Amit Gefen
Publsiher: Academic Press
Total Pages: 464
Release: 2019-10-20
ISBN 10: 0128150297
ISBN 13: 9780128150290
Language: EN, FR, DE, ES & NL

Innovations and Emerging Technologies in Wound Care Book Review:

Innovations and Emerging Technologies in Wound Care is a pivotal book on the prevention and management of chronic and non-healing wounds. The book clearly presents the research and evidence that should be considered when planning care interventions to improve health related outcomes for patients. New and emerging technologies are discussed and identified, along with tactics on how they can be integrated into clinical practice. This book offers readers a bridge between biomedical engineering and medicine, with an emphasis on technological innovations. It includes contributions from engineers, scientists, clinicians and industry professionals. Users will find this resource to be a complete picture of the latest knowledge on the tolerance of human tissues to sustained mechanical and thermal loads that also provides a deeper understanding of the risk for onset and development of chronic wounds. Describes the state-of-knowledge in wound research, including tissue damage cascades and healing processes Covers all state-of-the-art technology in wound prevention, diagnosis, prognosis and treatment Discusses emerging research directions and future technology trends in the field of wound prevention and care Offers a bench-to-bedside exploration of the key issues that affect the practice of prevention and management of non-healing wounds

Mechanobiology Handbook Second Edition

Mechanobiology Handbook  Second Edition
Author: Jiro Nagatomi,Eno Essien Ebong
Publsiher: CRC Press
Total Pages: 682
Release: 2018-12-07
ISBN 10: 042981674X
ISBN 13: 9780429816741
Language: EN, FR, DE, ES & NL

Mechanobiology Handbook Second Edition Book Review:

Mechanobiology—the study of the effects of mechanics on biological events—has evolved to answer numerous research questions. Mechanobiology Handbook 2nd Edition is a reference book for engineers, scientists, and clinicians who are interested in mechanobiology and a textbook for senior undergraduate to graduate level students of this growing field. Readers will gain a comprehensive review of recent research findings as well as elementary chapters on solid mechanics, fluid mechanics, and molecular analysis techniques. The new edition presents, in addition to the chapters of the first edition, homework problem sets that are available online and reviews of research in uncovered areas. Moreover, the new edition includes chapters on statistical analysis, design of experiments and optical imaging. The editors of this book are researchers and educators in mechanobiology. They realized a need for a single volume to assist course instructors as a guide for didactic teaching of mechanobiology to a diverse student body. A mechanobiology course is frequently made up of both undergraduate and graduate students pursuing degrees in engineering, biology, or integrated engineering and biology. Their goal was to present both the elementary and cutting-edge aspects of mechanobiology in a manner that is accessible to students from many different academic levels and from various disciplinary backgrounds. Moreover, it is their hope that the readers of Mechanobiology Handbook 2nd Edition will find study questions at the end of each chapter useful for long-term learning and further discussion. Comprehensive collection of reviews of recent research Introductory materials in mechanics, biology, and statistics Discussion of pioneering and emerging mechanobiology concepts Presentation of cutting-edge mechanobiology research findings across various fields and organ systems End of chapter study questions, available online Considering the complexity of the mechanics and the biology of the human body, most of the world of mechanobiology remains to be studied. Since the field is still developing, the Mechanobiology Handbook raises many different viewpoints and approaches with the intention of stimulating further research endeavours.

Biomaterials for Bone Tissue Engineering

Biomaterials for Bone Tissue Engineering
Author: José A. Sanz-Herrera
Publsiher: MDPI
Total Pages: 244
Release: 2020-05-27
ISBN 10: 3039289659
ISBN 13: 9783039289653
Language: EN, FR, DE, ES & NL

Biomaterials for Bone Tissue Engineering Book Review:

Bone tissue engineering aims to develop artificial bone substitutes that partially or totally restore the natural regeneration capability of bone tissue lost under circumstances of injury, significant defects, or diseases such as osteoporosis. In this context, biomaterials are the keystone of the methodology. Biomaterials for bone tissue engineering have evolved from biocompatible materials that mimic the physical and chemical environment of bone tissue to a new generation of materials that actively interacts with the physiological environment, accelerating bone tissue growth. Mathematical modelling and simulation are important tools in the overall methodology. This book presents an overview of the current investigations and recent contributions in the field of bone tissue engineering. It includes several successful examples of multidisciplinary collaboration in this transversal area of research. The book is intended for students, researchers, and professionals of a number of disciplines, such as engineering, mathematics, physics, chemistry, biomedicine, biology, and veterinary. The book is composed of an editorial section and 16 original research papers authored by leading researchers of this discipline from different laboratories across the world

The Nutritional Biochemistry of Chromium III

The Nutritional Biochemistry of Chromium III
Author: John Vincent
Publsiher: Elsevier
Total Pages: 292
Release: 2011-10-13
ISBN 10: 9780080475394
ISBN 13: 0080475396
Language: EN, FR, DE, ES & NL

The Nutritional Biochemistry of Chromium III Book Review:

Chromium nutritional supplements are the second best selling mineral supplements after calcium as chromium is found in pills, sports drinks, chewing gums, smoothies, and numerous other products. Chromium has been promoted to promote weight loss and muscle development and most recently to be available to treat the symptoms of type 2 diabetes and related conditions. The aim of The Nutritional Biochemistry of Chromium(III) is to examine the four most controversial areas of chromium nutrition and biochemistry: - is chromium an essential element for humans and are chromium nutritional supplements of value? - what biochemical role, if any, does chromium play in the body - can large doses of chromium(III) be used to treat symptoms of type 2 diabetes, cardiovascular disease, and related medical conditions - is the use of chromium(III) supplements a health concern. Scientific experts, who are recognized leaders in the field, weigh in with their opinions on both sides of these issues in this book. A background review of the field from 1955-1995 by Vincent opens the book and concludes with a summary by Dr. Forrest Nielsen, Center Director of the USDA's Grand Forks Human Nutrition Research Center concludes the book. * Point-counterpoint format, providing both sides of major issues * Complete coverage of current issues, including nutrition, health, biochemical role and toxicology * Authors are recognised experts and leaders in this field

Biological Physical and Technical Basics of Cell Engineering

Biological  Physical and Technical Basics of Cell Engineering
Author: Gerhard M. Artmann,Aysegül Artmann,Azhar A. Zhubanova,Ilya Digel
Publsiher: Springer
Total Pages: 481
Release: 2018-04-11
ISBN 10: 9811079048
ISBN 13: 9789811079047
Language: EN, FR, DE, ES & NL

Biological Physical and Technical Basics of Cell Engineering Book Review:

This book presents and discusses recent scientific progress on Cell and Stem Cell Engineering. It predominantly focuses on Biological, Physical and Technical Basics, and features new trends of research reaching far into the 21st century.

Biomaterials for Organ and Tissue Regeneration

Biomaterials for Organ and Tissue Regeneration
Author: Nihal Vrana,Helena Knopf-Marques,Julien Barthes
Publsiher: Woodhead Publishing
Total Pages: 846
Release: 2020-03-20
ISBN 10: 0081029071
ISBN 13: 9780081029077
Language: EN, FR, DE, ES & NL

Biomaterials for Organ and Tissue Regeneration Book Review:

Biomaterials for Organ and Tissue Regeneration: New Technologies and Future Prospects examines the use of biomaterials in applications related to artificial tissues and organs. With a strong focus on fundamental and traditional tissue engineering strategies, the book also examines how emerging and enabling technologies are being developed and applied. Sections provide essential information on biomaterial, cell properties and cell types used in organ generation. A section on state-of-the-art in organ regeneration for clinical purposes is followed by a discussion on enabling technologies, such as bioprinting, on chip organ systems and in silico simulations. Provides a systematic overview of the field, from fundamentals, to current challenges and opportunities Encompasses the classic paradigm of tissue engineering for creation of new functional tissue Discusses enabling technologies such as bioprinting, organ-on-chip systems and in silico simulations

Mechanobiology in Health and Disease

Mechanobiology in Health and Disease
Author: Stefaan Verbruggen
Publsiher: Academic Press
Total Pages: 527
Release: 2018-08-09
ISBN 10: 0128129530
ISBN 13: 9780128129531
Language: EN, FR, DE, ES & NL

Mechanobiology in Health and Disease Book Review:

Mechanobiology in Health and Disease brings together contributions from leading biologists, clinicians, physicists and engineers in one convenient volume, providing a unified source of information for researchers in this highly multidisciplinary area. Opening chapters provide essential background information on cell mechanotransduction and essential mechanobiology methods and techniques. Other sections focus on the study of mechanobiology in healthy systems, including bone, tendons, muscles, blood vessels, the heart and the skin, as well as mechanobiology studies of pregnancy. Final chapters address the nascent area of mechanobiology in disease, from the study of bone conditions, skin diseases and heart diseases to cancer. A discussion of future perspectives for research completes each chapter in the volume. This is a timely resource for both early-career and established researchers working on mechanobiology. Provides an essential digest of primary research from many fields and disciplines in one convenient volume Covers both experimental approaches and descriptions of mechanobiology problems from mathematical and numerical perspectives Addresses the hot topic of mechanobiology in disease, a particularly dynamic field of frontier science

Type 2 Diabetes

Type 2 Diabetes
Author: Robert Fried,Richard M. Carlton
Publsiher: CRC Press
Total Pages: 482
Release: 2018-10-25
ISBN 10: 042901676X
ISBN 13: 9780429016769
Language: EN, FR, DE, ES & NL

Type 2 Diabetes Book Review:

Approximately 29 million Americans are diagnosed with Type 2 diabetes annually. Of that number, only about 36 percent (10.44 million diabetes sufferers) achieve satisfactory medical outcomes and would need additional help—rarely available—to reliably control their glucose levels. Contrary to popular belief, although anti-diabetic medications can lower sugar levels, nevertheless they have a poor performance track record because inflammation in the blood vessels persists. This book details recent scientific findings that cardiovascular, kidney, vision, peripheral nervous system, and other body damage caused by chronic high levels of blood sugar (hyperglycemia) in Type 2 diabetes is actually due to excessive generation of unopposed free radicals and reactive oxygen species (ROS). These, in turn, cause chronic systemic inflammation and dysfunction of the endothelial lining of the arterial blood vessels, jeopardizing the formation of the protective molecule nitric oxide (NO), thus severely impairing the blood supply to every organ and tissue in the body. This book also catalogues the evidence that chronic hyperglycemia causes profound and often irreversible damage—even long before Type 2 diabetes has been diagnosed. In addition, because conventional prescription treatments are, unfortunately, often inadequate, the book details evidence-based complementary means of blood sugar control.

Multiscale Mechanobiology of Bone Remodeling and Adaptation

Multiscale Mechanobiology of Bone Remodeling and Adaptation
Author: Peter Pivonka
Publsiher: Springer
Total Pages: 324
Release: 2017-07-27
ISBN 10: 3319588451
ISBN 13: 9783319588452
Language: EN, FR, DE, ES & NL

Multiscale Mechanobiology of Bone Remodeling and Adaptation Book Review:

The book presents state-of-the-art developments in multiscale modeling and latest experimental data on multiscale mechanobiology of bone remodeling and adaptation including fracture healing applications. The multiscale models include musculoskeletal models describing bone-muscle interactions during daily activities such as walking or running, micromechanical models for estimation of bone mechanical properties, bone remodeling and adaptation models, cellular models describing the complex bone-cell interactions taking into account biochemical and biomechanical regulatory factors. Also subcellular processes are covered including arrangement of actin filaments due to mechanical loading and change of receptor configurations.