The Neurobiology of Schizophrenia

The Neurobiology of Schizophrenia
Author: Ted Abel,Thomas Nickl-Jockschat
Publsiher: Academic Press
Total Pages: 468
Release: 2016-07-08
ISBN 10: 0128018771
ISBN 13: 9780128018774
Language: EN, FR, DE, ES & NL

The Neurobiology of Schizophrenia Book Review:

The Neurobiology of Schizophrenia begins with an overview of the various facets and levels of schizophrenia pathophysiology, ranging systematically from its genetic basis over changes in neurochemistry and electrophysiology to a systemic neural circuits level. When possible, the editors point out connections between the various systems. The editors also depict methods and research strategies used in the respective field. The individual backgrounds of the two editors promote a synthesis between basic neuroscience and clinical relevance. Provides a comprehensive overview of neurobiological aspects of schizophrenia Discusses schizophrenia at behavioral, cognitive, clinical, electrophysiological, molecular, and genetic levels Edited by a translational researcher and a psychiatrist to promote synthesis between basic neuroscience and clinical relevance Elucidates connections between the various systems depicted, when possible

Neurobiology of Mental Illness

Neurobiology of Mental Illness
Author: Dennis S. Charney,Eric J. Nestler,Pamela Sklar,Joseph D. Buxbaum
Publsiher: Oxford University Press
Total Pages: 1222
Release: 2013-07-04
ISBN 10: 0199934959
ISBN 13: 9780199934959
Language: EN, FR, DE, ES & NL

Neurobiology of Mental Illness Book Review:

Our understanding of the neurobiological basis of psychiatric disease has accelerated in the past five years. The fourth edition of Neurobiology of Mental Illness has been completely revamped given these advances and discoveries on the neurobiologic foundations of psychiatry. Like its predecessors the book begins with an overview of the basic science. The emerging technologies in Section 2 have been extensively redone to match the progress in the field including new chapters on the applications of stem cells, optogenetics, and image guided stimulation to our understanding and treatment of psychiatric disorders. Sections' 3 through 8 pertain to the major psychiatric syndromes-the psychoses, mood disorders, anxiety disorders, substance use disorders, dementias, and disorders of childhood-onset. Each of these sections includes our knowledge of their etiology, pathophysiology, and treatment. The final section discusses special topic areas including the neurobiology of sleep, resilience, social attachment, aggression, personality disorders and eating disorders. In all, there are 32 new chapters in this volume including unique insights on DSM-5, the Research Domain Criteria (RDoC) from NIMH, and a perspective on the continuing challenges of diagnosis given what we know of the brain and the mechanisms pertaining to mental illness. This book provides information from numerous levels of analysis including molecular biology and genetics, cellular physiology, neuroanatomy, neuropharmacology, epidemiology, and behavior. In doing so it translates information from the basic laboratory to the clinical laboratory and finally to clinical treatment. No other book distills the basic science and underpinnings of mental disorders and explains the clinical significance to the scope and breadth of this classic text. The result is an excellent and cutting-edge resource for psychiatric residents, psychiatric researchers and doctoral students in neurochemistry and the neurosciences.

Advances in the Neurobiology of Schizophrenia

Advances in the Neurobiology of Schizophrenia
Author: Johan A. den Boer,H. G. M. Westenberg,Herman M. Van Praag
Publsiher: John Wiley & Son Limited
Total Pages: 469
Release: 1995-07-11
ISBN 10:
ISBN 13: UVA:X002680189
Language: EN, FR, DE, ES & NL

Advances in the Neurobiology of Schizophrenia Book Review:

Recent years have witnessed major advances in the study of neuroscience which have increased our understanding of the relationship between cerebral processes and behavioural, cognitive and emotional disorders. This series aims to monitor important research developments in the field of biological psychiatry and their relevance to clinical practice. Since the 1950s there has been significant progress in our understanding of the neurobiology of schizophrenia. This important volume illustrates these new developments, particularly in terms of pharmacotherapeutics, pathogenesis and research methodology. Eminent scientists from around the world discuss conceptual issues, epidemiology, genetic analysis of psychotic disturbances, neuropathological changes and brain imaging studies, atypical neuroleptics, psychopharmacology of schizophrenia, neuropeptide involvement, neurophysiology and information processing in schizophrenia. Also highlighted are the similarities between childhood developmental disorders and schizophrenia, as well as the relatively neglected area of biological factors in childhood psychosis and their predictive value in adult psychopathology. Psychiatrists, neuroscientists, pharmacologists, psychologists, physicians and general practitioners will find this authoritative state-of-the-art review important and informative reading.

Behavioral Neurobiology of Schizophrenia and Its Treatment

Behavioral Neurobiology of Schizophrenia and Its Treatment
Author: Neal R. Swerdlow
Publsiher: Springer Science & Business Media
Total Pages: 666
Release: 2010-08-19
ISBN 10: 9783642137174
ISBN 13: 3642137172
Language: EN, FR, DE, ES & NL

Behavioral Neurobiology of Schizophrenia and Its Treatment Book Review:

This book describes the state-of-the-art of treatment of schizophrenia and reflects its development in 22 chapters written by leading authorities in the field

Neurobiology of Brain Disorders

Neurobiology of Brain Disorders
Author: Michael J. Zigmond,Joseph T. Coyle,Lewis P. Rowland
Publsiher: Elsevier
Total Pages: 824
Release: 2014-12-03
ISBN 10: 0123982804
ISBN 13: 9780123982803
Language: EN, FR, DE, ES & NL

Neurobiology of Brain Disorders Book Review:

Neurobiology of Brain Disorders is the first book directed primarily at basic scientists to offer a comprehensive overview of neurological and neuropsychiatric disease. This book links basic, translational, and clinical research, covering the genetic, developmental, molecular, and cellular mechanisms underlying all major categories of brain disorders. It offers students, postdoctoral fellows, and researchers in the diverse fields of neuroscience, neurobiology, neurology, and psychiatry the tools they need to obtain a basic background in the major neurological and psychiatric diseases, and to discern connections between basic research and these relevant clinical conditions. This book addresses developmental, autoimmune, central, and peripheral neurodegeneration; infectious diseases; and diseases of higher function. The final chapters deal with broader issues, including some of the ethical concerns raised by neuroscience and a discussion of health disparities. Included in each chapter is coverage of the clinical condition, diagnosis, treatment, underlying mechanisms, relevant basic and translational research, and key unanswered questions. Written and edited by a diverse team of international experts, Neurobiology of Brain Disorders is essential reading for anyone wishing to explore the basic science underlying neurological and neuropsychiatric diseases. Links basic, translational, and clinical research on disorders of the nervous system, creating a format for study that will accelerate disease prevention and treatment Covers a vast array of neurological disorders, including ADHD, Down syndrome, autism, muscular dystrophy, diabetes, TBI, Parkinson, Huntington, Alzheimer, OCD, PTSD, schizophrenia, depression, and pain Illustrated in full color Each chapter provides in-text summary points, special feature boxes, and research questions Provides an up-to-date synthesis of primary source material

Neurobiology of Psychiatric Disorders

Neurobiology of Psychiatric Disorders
Author: Thomas E. Schlaepfer,Charles B. Nemeroff
Publsiher: Elsevier
Total Pages: 760
Release: 2012
ISBN 10: 0444520023
ISBN 13: 9780444520029
Language: EN, FR, DE, ES & NL

Neurobiology of Psychiatric Disorders Book Review:

This new volume in the Handbook of Clinical Neurology presents a comprehensive review of the fundamental science and clinical treatment of psychiatric disorders. Advances in neuroscience have allowed for dramatic advances in the understanding of psychiatric disorders and treatment. Brain disorders, such as depression and schizophrenia, are the leading cause of disability worldwide. It is estimated that over 25% of the adult population in North America are diagnosed yearly with at least one mental disorder and similar results hold for Europe. Now that neurology and psychiatry agree that all mental disorders are in fact, "brain diseases," this volume provides a foundational introduction to the science defining these disorders and details best practices for psychiatric treatment. Provides a comprehensive review of the scientific foundations of psychiatric disorders and psychiatric treatment Includes detailed results from genetics, molecular biology, brain imaging, and neuropathological, immunological, epidemiological, metabolic, therapeutic and historical aspects of the major psychiatric disorders A "must have" reference and resource for neuroscientists, neurologists, psychiatrists, and clinical psychologists as well as all research scientists investigating disorders of the brain

Integrating the Neurobiology of Schizophrenia

Integrating the Neurobiology of Schizophrenia
Author: Anonim
Publsiher: Elsevier
Total Pages: 480
Release: 2007-02-27
ISBN 10: 9780080475080
ISBN 13: 0080475086
Language: EN, FR, DE, ES & NL

Integrating the Neurobiology of Schizophrenia Book Review:

This book examines the role that dopamine plays in schizophrenia, examining its role in not only the symptoms of the disease but also in its treatment. It also reviews all neurotransmitters that have been implicated in schizophrenia, exploring the genetic data, clinical data implicating the transmitter, and the preclinical data exploring how a transmitter may interact with dopamine and contribute to the dopaminergic phenotype observed in the illness. This book will serve as an educational tool for instructors, a guide for clinicians, and be of interest to researchers. It is a good reference for researchers specialized in one particular area and interested in learning about other areas of pathology in schizophrenia and how they may all feed into each other. The book concludes with an overall integrative model assembling as many of these elements as possible.

Charney Nestler s Neurobiology of Mental Illness

Charney   Nestler s Neurobiology of Mental Illness
Author: Dennis S. Charney,Pamela B. Sklar
Publsiher: Oxford University Press
Total Pages: 1024
Release: 2018-01-12
ISBN 10: 019068142X
ISBN 13: 9780190681425
Language: EN, FR, DE, ES & NL

Charney Nestler s Neurobiology of Mental Illness Book Review:

Preceded by Neurobiology of mental illness / edited by Dennis S. Charney ... [et al.]. 4th ed. 2013.

The Neuroscience of Clinical Psychiatry

The Neuroscience of Clinical Psychiatry
Author: Edmund S. Higgins,Mark S. George
Publsiher: Lippincott Williams & Wilkins
Total Pages: 302
Release: 2012-11-05
ISBN 10: 1469802007
ISBN 13: 9781469802008
Language: EN, FR, DE, ES & NL

The Neuroscience of Clinical Psychiatry Book Review:

Bringing the latest breakthroughs in neuroscience to the clinician, this text provides resident and practicing psychiatrists with a comprehensive, clinically relevant overview of the brain mechanisms underlying behavior and mental illness. The book presents an integrated perspective on the structures and workings of the brain, the mechanisms governing behaviors such as pleasure, aggression, and intelligence, and the pathophysiology of mental disorders. More than 200 two-color illustrations clarify key concepts. Questions and answers at the end of each chapter facilitate review and board preparation. Readers will also have online access to the complete, fully searchable text and a quiz bank of over 150 questions at www.neuroscienceofclinicalpsychiatry.com.

Handbook of Schizophrenia Spectrum Disorders Volume I

Handbook of Schizophrenia Spectrum Disorders  Volume I
Author: Michael S Ritsner
Publsiher: Springer Science & Business Media
Total Pages: 494
Release: 2011-04-06
ISBN 10: 9789400708372
ISBN 13: 9400708378
Language: EN, FR, DE, ES & NL

Handbook of Schizophrenia Spectrum Disorders Volume I Book Review:

A few disorders have some of the same symptoms as schizophrenia including schizoaffective disorders, schizophreniform disorder, schizotypal and schizoid personality disorders, delusional disorder, and autism (schizophrenia spectrum disorders). Since the 2000 there has been significant progress in our understanding of the early presentations, assessment, suspected neuropathology, and treatment of these disorders. Recent technological breakthroughs in basic sciences hold promise for advancing our understanding of the pathophysiology of schizophrenia spectrum disorders. This collective monograph reviewers recent researches regarding the origins, onset, course, and outcome of schizophrenia spectrum disorders. In particular, this book will be illustrate new developments in terms of conceptual models, and research methodology, genetics and genomics, brain imaging and neurochemical studies, neurophysiology and information processing in schizophrenia spectrum disorders patients. Also will be highlighted new developments in our understanding of the childhood psychosis, prodromal and first-episode states, in treatment and rehabilitation. Thus, the purpose of this book is to provide up-to-date overview of the rapid advances made in the clinical and basic science studies supporting our understanding of the relationship between cerebral processes and clinical, cognitive and other presentations of the schizophrenia spectrum disorders. In addition, this book aims to monitor important research developments, which may be relevant to treatment, and rehabilitation of patients.

Neurobiology of Bipolar Disorder

Neurobiology of Bipolar Disorder
Author: Joao Quevedo,Andre Ferrer Carvalho,Eduard Vieta
Publsiher: Academic Press
Total Pages: 470
Release: 2020-11-25
ISBN 10: 012819183X
ISBN 13: 9780128191835
Language: EN, FR, DE, ES & NL

Neurobiology of Bipolar Disorder Book Review:

The Neurobiology of Bipolar Disorder: Road to Novel Therapeutics combines the basic neurobiology of bipolar disorder with discussions of the most recent advances in research, including the interacting pathways implicated in the pathophysiology of bipolar disorder, genetic approaches and the pharmacogenomics of bipolar disorder. The basic foundational understanding of the neurobiology underlying the disorder, along with a comprehensive summary of the most recent advances in research combine to aid advanced students and researchers in their understanding of bipolar disorder management using novel and fast-acting pharmaceutical and neuromodulatory approaches. Aids readers in understanding bipolar disorder in the context of NIMH Research Domain Criteria (RDoC) recommendations Covers a range of existing and potential pharmacologic and non-pharmacologic treatment options, from lifestyle adjustments to novel therapeutics Synthesizes a discussion of the cellular and molecular mechanisms underlying symptoms with clinical aspects of bipolar disorder

Social Cognition in Psychosis

Social Cognition in Psychosis
Author: Eve Lewandowski,Ahmed A. Moustafa
Publsiher: Academic Press
Total Pages: 348
Release: 2019-05
ISBN 10: 0128153156
ISBN 13: 9780128153154
Language: EN, FR, DE, ES & NL

Social Cognition in Psychosis Book Review:

Social Cognition in Psychosis combines current research on phenotypes, neurobiology, and existing evidence on the assessment and treatment of various forms of psychoses. The book presents various treatment options, including assessment approaches, tools and training methods that aid in the rehabilitation of patients with psychotic disorders. Social cognition is a set of psychological processes related to understanding, recognizing, processing and appropriately using social stimuli in one's environment. Individuals with psychotic disorders consistently exhibit impairments in social cognition. As a result, social cognition has been an important target for intervention, with recent efforts trying to enhance early recovery among individuals with psychotic disorders. Provides an overview of social cognition in relation to various forms of psychotic disorders Includes assessment and treatment for social cognition dysfunction in psychoses Discusses the genetics and heritability theory of social cognitive dysfunction in psychosis Defines the neurobiology of social cognitive dysfunctions

Neuroscience for the Mental Health Clinician

Neuroscience for the Mental Health Clinician
Author: Steven R. Pliszka
Publsiher: Guilford Press
Total Pages: 280
Release: 2004-09-29
ISBN 10: 9781593850784
ISBN 13: 1593850786
Language: EN, FR, DE, ES & NL

Neuroscience for the Mental Health Clinician Book Review:

As scientific knowledge grows about the role of the brain in mental disorder, no clinician can afford to be uninformed about neurobiology. This accessible primer provides the basic grounding in neuroscience that all contemporary mental health professionals need. Readers are first guided through the fundamentals of neuroanatomy, neurochemistry, and psychiatric genetics. Chapters then illuminate the neurobiological underpinnings of a range of frequently encountered disorders--including ADHD, substance abuse, mood and anxiety disorders, schizophrenia, and learning and cognitive problems--giving particular attention to the impact of psychosocial risk factors on the brain. Also examined are ways that both pharmacological and psychological interventions have been shown to alter brain chemistry as they bring about a reduction in symptoms.

Neurobiology Clinical Course and Therapeutic Approaches of Treatment Resistant Schizophrenia Toward an Integrated View

Neurobiology  Clinical Course  and Therapeutic Approaches of Treatment Resistant Schizophrenia  Toward an Integrated View
Author: Felice Iasevoli,Vincenzo De Luca,Frederick Charles Nucifora
Publsiher: Frontiers Media SA
Total Pages: 329
Release: 2020-01-13
ISBN 10: 2889633314
ISBN 13: 9782889633319
Language: EN, FR, DE, ES & NL

Neurobiology Clinical Course and Therapeutic Approaches of Treatment Resistant Schizophrenia Toward an Integrated View Book Review:

Schizophrenia

Schizophrenia
Author: Neil A. Rector,Neal Stolar,Paul Grant
Publsiher: Guilford Press
Total Pages: 418
Release: 2011-03-01
ISBN 10: 1609182383
ISBN 13: 9781609182380
Language: EN, FR, DE, ES & NL

Schizophrenia Book Review:

From Aaron T. Beck and colleagues, this is the definitive work on the cognitive model of schizophrenia and its treatment. The volume integrates cognitive-behavioral and biological knowledge into a comprehensive conceptual framework. It examines the origins, development, and maintenance of key symptom areas: delusions, hallucinations, negative symptoms, and formal thought disorder. Treatment chapters then offer concrete guidance for addressing each type of symptom, complete with case examples and session outlines. Anyone who treats or studies serious mental illness will find a new level of understanding together with theoretically and empirically grounded clinical techniques.

Neuroimaging in Schizophrenia

Neuroimaging in Schizophrenia
Author: Marek Kubicki,Martha E. Shenton
Publsiher: Springer Nature
Total Pages: 437
Release: 2020-02-18
ISBN 10: 3030352064
ISBN 13: 9783030352066
Language: EN, FR, DE, ES & NL

Neuroimaging in Schizophrenia Book Review:

This comprehensive book explains the importance of imaging techniques in exploring and understanding the role of brain abnormalities in schizophrenia. The findings obtained using individual imaging modalities and their biological interpretation are reviewed in detail, and updates are provided on methodology, testable hypotheses, limitations, and new directions for research. The coverage also includes important recent applications of neuroimaging to schizophrenia, for example in relation to non-pharmacological interventions, brain development, genetics, and prediction of treatment response and outcome. Written by world renowned experts in the field, the book will be invaluable to all who wish to learn about the newest and most important developments in neuroimaging research in schizophrenia, how these developments relate to the last 30 years of research, and how they can be leveraged to bring us closer to a cure for this devastating disorder. Neuroimaging in Schizophrenia will assist clinicians in navigating what is an extremely complex field and will be a source of insight and stimulation for researchers.

Neurobiology of Depression

Neurobiology of Depression
Author: Joao Luciano de Quevedo,Andre Ferrer Carvalho,Carlos A. Zarate
Publsiher: Academic Press
Total Pages: 471
Release: 2019-01-03
ISBN 10: 0128133341
ISBN 13: 9780128133347
Language: EN, FR, DE, ES & NL

Neurobiology of Depression Book Review:

Neurobiology of Depression: Road to Novel Therapeutics synthesizes the basic neurobiology of major depressive disorder with discussions on the most recent advances in research, including the interacting pathways implicated in the pathophysiology of MDD, omics technologies, genetic approaches, and the development of novel optogenetic approaches that are changing research perspectives and revolutionizing research into depression. These basic foundational understandings on the neurobiology underlying the disorder, along with a comprehensive summary of the most recent advances in research are combined in this book to aid advanced students and researchers in their understanding of MDD. Depression is one of the most common mental-health disorders caused by a variety of genetic, biological, environmental and psychological factors. Major depressive disorder (MDD) is typically treated with first-line antidepressant agents that primarily target monoamine neurotransmission. However, only approximately one-third of patients with MDD achieve remission following a trial with such an antidepressant. Furthermore, MDD is a heterogeneous phenotype, and new frameworks, such as the NIMH Research Domain Criteria (RDoC) may provide a more accurate, biologically based comprehension of the symptomatic heterogeneity of this devastating illness. Aids readers in understanding major depressive disorder in the context of NIMH Research Domain Criteria (RDoC) recommendations Covers a range of existing and potential pharmacologic and non-pharmacologic treatment options, from lifestyle adjustments, to antidepressants and novel therapeutics Synthesizes discussions on the cellular and molecular mechanisms underlying symptoms with the clinical aspects of depression

Genomics Circuits and Pathways in Clinical Neuropsychiatry

Genomics  Circuits  and Pathways in Clinical Neuropsychiatry
Author: Thomas Lehner,Bruce L. Miller,Matthew W. State
Publsiher: Academic Press
Total Pages: 796
Release: 2016-06-07
ISBN 10: 0128005300
ISBN 13: 9780128005309
Language: EN, FR, DE, ES & NL

Genomics Circuits and Pathways in Clinical Neuropsychiatry Book Review:

This foundational work comprehensively examines the current state of the genetics, genomics and brain circuitry of psychiatric and neurological disorders. It consolidates discoveries of specific genes and genomic regions associated with these conditions, the genetic and anatomic architecture of these syndromes, and addresses how recent advances in genomics are leading to a reappraisal of the biology underlying clinical neuroscience. In doing so, it critically examines the promise and limitations of these discoveries toward treatment, and to the interdisciplinary nature of understanding brain and behavior. Coverage includes new discoveries regarding autism, epilepsy, intellectual disability, dementias, movement disorders, language impairment, disorders of attention, schizophrenia, and bipolar disorder. Genomics, Circuits, and Pathways in Clinical Neuropsychiatry focuses on key concepts, challenges, findings, and methods in genetics, genomics, molecular pathways, brain circuitry, and related neurobiology of neurologic and psychiatric disorders. Provides interdisciplinary appeal in psychiatry, neurology, neuroscience, and genetics Identifies key concepts, methods, and findings Includes coverage of multiple disorders from autism to schizophrenia Reviews specific genes associated with disorders Discusses the genetic architecture of these syndromes Explains how recent findings are influencing the understanding of biology Clarifies the promise of these findings for future treatment

Neurobiology of Mood Disorders

Neurobiology of Mood Disorders
Author: Bruno P. Guiard,Eliyahu Dremencov
Publsiher: Bentham Science Publishers
Total Pages: 300
Release: 2014-02-27
ISBN 10: 1608054675
ISBN 13: 9781608054671
Language: EN, FR, DE, ES & NL

Neurobiology of Mood Disorders Book Review:

This monograph is a collection of selected articles on the subject of mood disorders such as depression and schizophrenia. It is divided into 3 sections: 1) Research methods in psychopharmacology - which highlights some established experimental techniques to study mood disorders in human and relevant animal models, 2) Pathophysiology of mood disorders – which explains the physiological and pharmacological mechanisms responsible for mood disorders and 3) New strategies for the treatment of mood disorders – a concluding section that provides recent examples on the beneficial effects of pharmacological and non-pharmacological interventions in the relief of mood disorders. The e-book serves as a primer for graduate students and researchers interested in the physiology and treatment of affective psychological disorders.

Handbook of the Behavioral Neurobiology of Serotonin

Handbook of the Behavioral Neurobiology of Serotonin
Author: Christian P. Muller,Barry Jacobs
Publsiher: Academic Press
Total Pages: 836
Release: 2009-12-30
ISBN 10: 9780080878171
ISBN 13: 0080878172
Language: EN, FR, DE, ES & NL

Handbook of the Behavioral Neurobiology of Serotonin Book Review:

Serotonin (5-hydroxytryptamine, often cited as 5-HT) is one of the major excitatory neurotransmitter, and the serotonergic system is one of the best studied and understood transmitter systems. It is crucially involved in the organization of virtually all behaviours and in the regulation of emotion and mood. Alterations in the serotonergic system, induced by e.g. learning or pathological processes, underlie behavioural plasticity and changes in mood, which can finally results in abnormal behaviour and psychiatric conditions. Not surprisingly, the serotonergic system and its functional components appear to be targets for a multitude of pharmacological treatments - examples of very successful drugs targeting the serotoninergic system include Prozac and Zoloft. The last decades of research have not only fundamentally expanded our view on serotonin but also revealed in much more detail an astonishing complexity of this system, which comprises a multitude of receptors and signalling pathways. A detailed view on its role in basal, but also complex, behaviours emerged, and, was presented in a number of single review articles. Although much is known now, the serotonergic system is still a fast growing field of research contributing to our present understanding of the brains function during normal and disturbed behaviour. This handbook aims towards a detailed and comprehensive overview over the many facets of behavioural serotonin research. As such, it will provide the most up to date and thorough reading concerning the serotonergic systems control of behaviour and mood in animals and humans. The goal is to create a systematic overview and first hand reference that can be used by students and scholars alike in the fields of genetics, anatomy, pharmacology, physiology, behavioural neuroscience, pathology, and psychiatry. The chapters in this book will be written by leading scientists in this field. Most of them have already written excellent reviews in their field of expertise. The book is divided in 4 sections. After an historical introduction, illustrating the growth of ideas about serotonin function in behaviour of the last forty years, section A will focus on the functional anatomy of the serotonergic system. Section B provides a review of the neurophysiology of the serotonergic system and its single components. In section C the involvement of serotonin in behavioural organization will be discussed in great detail, while section D deals with the role of serotonin in behavioural pathologies and psychiatric disorders. The first handbook broadly discussing the behavioral neurobiology of the serotonorgic transmitter system Co-edited by one of the pioneers and opinion leaders of the past decades, Barry Jacobs (Princeton), with an international list (10 countries) of highly regarded contributors providing over 50 chapters, and including the leaders in the field in number of articles and citations: K. P. Lesch, T. Sharp, A. Caspi, P. Blier, G.K. Aghajanian, E. C. Azmitia, and others The only integrated and complete resource on the market containing the best information integrating international research, providing a global perspective to an international community Of great value not only for researchers and experts, but also for students and clinicians as a background reference