The Mouse in Biomedical Research History genetics and wild mice

The Mouse in Biomedical Research  History  genetics  and wild mice
Author: Henry L. Foster,J. David Small,James G. Fox,James G Fox
Publsiher: Unknown
Total Pages: 306
Release: 1981
ISBN 10:
ISBN 13: UOM:39015004379866
Language: EN, FR, DE, ES & NL

The Mouse in Biomedical Research History genetics and wild mice Book Review:

The Mouse in Biomedical Research

The Mouse in Biomedical Research
Author: Henry L. Foster,J. David Small,James G. Fox
Publsiher: Unknown
Total Pages: 390
Release: 1981
ISBN 10:
ISBN 13: UOM:39015003223545
Language: EN, FR, DE, ES & NL

The Mouse in Biomedical Research Book Review:

The Mouse in Biomedical Research

The Mouse in Biomedical Research
Author: Anonim
Publsiher: Elsevier
Total Pages: 816
Release: 2006-12-15
ISBN 10: 9780080469072
ISBN 13: 0080469078
Language: EN, FR, DE, ES & NL

The Mouse in Biomedical Research Book Review:

Normative Biology, Husbandry, and Models, the third volume in the four volume set, The Mouse in Biomedical Research, encompasses 23 chapters whose contents provide a broad overview on the laboratory mouse’s normative biology, husbandry, and its use as a model in biomedical research. This consists of chapters on behavior, physiology, reproductive physiology, anatomy, endocrinology, hematology, and clinical chemistry. Other chapters cover management, as well as nutrition, gnotobiotics and disease surveillance. There are also individual chapters describing the mouse as a model for the study of aging, eye research, neurodegenerative diseases, convulsive disorders, diabetes, and cardiovascular and skin diseases. Chapters on imaging techniques and the use of the mouse in assays of biological products are also included.

Making Mice

Making Mice
Author: Karen Rader
Publsiher: Princeton University Press
Total Pages: 329
Release: 2018-06-05
ISBN 10: 0691187584
ISBN 13: 9780691187587
Language: EN, FR, DE, ES & NL

Making Mice Book Review:

Making Mice blends scientific biography, institutional history, and cultural history to show how genetically standardized mice came to play a central role in contemporary American biomedical research. Karen Rader introduces us to mouse "fanciers" who bred mice for different characteristics, to scientific entrepreneurs like geneticist C. C. Little, and to the emerging structures of modern biomedical research centered around the National Institutes of Health. Throughout Making Mice, Rader explains how the story of mouse research illuminates our understanding of key issues in the history of science such as the role of model organisms in furthering scientific thought. Ultimately, genetically standardized mice became icons of standardization in biomedicine by successfully negotiating the tension between the natural and the man-made in experimental practice. This book will become a landmark work for its understanding of the cultural and institutional origins of modern biomedical research. It will appeal not only to historians of science but also to biologists and medical researchers.

Cellular and Animal Models in Human Genomics Research

Cellular and Animal Models in Human Genomics Research
Author: Anonim
Publsiher: Academic Press
Total Pages: 226
Release: 2019-07-30
ISBN 10: 012816574X
ISBN 13: 9780128165744
Language: EN, FR, DE, ES & NL

Cellular and Animal Models in Human Genomics Research Book Review:

Cellular and Animal Models in Human Genomics Research provides an indispensable resource for applying comparative genomics in the annotation of disease-gene associated variants that are identified by human genomic sequencing. The book presents a thorough overview of effective protocols for the use of cellular and animal modeling methods to turn lists of plausible genes into causative biomarkers. With chapters written by international experts, the book first addresses the fundamental aspects of using cellular and animal models in genetic and genomic studies, including in-depth examples of specific models and their utility, i.e., yeast, worms, flies, fish, mice and large animals. Protocols for properly conducting model studies, genomic technology, modeling candidate genes vs. genetic variants, integrative modeling, utilizing induced pluripotent stem cells, and employing CRISPR-Cas9 are also discussed in-depth. Provides a thorough, accessible resource that helps researchers and students employ cellular and animal models in their own genetic and genomic studies Offers guidance on how to effectively interpret the results and significance of genetic and genomic model studies for human health Features chapters from international experts in the use of specific cellular and animal models, including yeast, worms, flies, fish, mice, and large animals, among other organisms

The Minipig in Biomedical Research

The Minipig in Biomedical Research
Author: Peter A. McAnulty,Anthony D. Dayan,Niels-Christian Ganderup,Kenneth L. Hastings
Publsiher: CRC Press
Total Pages: 662
Release: 2011-12-19
ISBN 10: 1439811180
ISBN 13: 9781439811184
Language: EN, FR, DE, ES & NL

The Minipig in Biomedical Research Book Review:

The Minipig in Biomedical Research is a comprehensive resource for research scientists on the potential and use of the minipig in basic and applied biomedical research, and the development of drugs and chemicals. Written by acknowledged experts in the field, and drawing on the authors’ global contacts and experience with regulatory authorities and the pharmaceutical and other industries, this accessible manual ranges widely over the biological, scientific, and practical uses of the minipig in the laboratory. Its coverage extends from the minipig’s origins, anatomy, genetics, immunology, and physiology to its welfare, health, and husbandry; practical dosing and examination procedures; surgical techniques; and all areas of toxicity testing and the uses of the minipig as a disease model. Regulatory aspects of its use are considered. The reader will find an extensive amount of theoretical and practical information in the pharmacology; ADME and toxicology chapters which will help scientists and managers when deciding which species to use in basic research; drug discovery and pharmacology; and toxicology studies of chemicals, biotechnology products and devices. The book discusses regulatory uses of minipigs in the evaluation of human and veterinary pharmaceuticals, medical devices, and other classes of xenobiotics. It describes features of normal health, normal laboratory values, and common diseases. It also carefully elucidates ethical and legal considerations in their supply, housing, and transport. The result is an all-inclusive and up to date manual about the experimental uses of the minipig that describes ‘How to’ and ‘Why’ and ’What to expect in the normal’, combining enthusiasm and experience with critical assessment of its values and potential problems.

Sourcebook of Models for Biomedical Research

Sourcebook of Models for Biomedical Research
Author: P. Michael Conn
Publsiher: Springer Science & Business Media
Total Pages: 778
Release: 2008-03-07
ISBN 10: 1597452858
ISBN 13: 9781597452854
Language: EN, FR, DE, ES & NL

Sourcebook of Models for Biomedical Research Book Review:

The collection of systems represented in this volume is a unique effort to reflect the diversity and utility of models used in biomedicine. That utility is based on the consideration that observations made in particular organisms will provide insight into the workings of other, more complex systems. This volume is therefore a comprehensive and extensive collection of these important medical parallels.

Inbred Strains in Biomedical Research

Inbred Strains in Biomedical Research
Author: Anonim
Publsiher: Macmillan International Higher Education
Total Pages: 483
Release: 1979-11-10
ISBN 10: 1349038164
ISBN 13: 9781349038169
Language: EN, FR, DE, ES & NL

Inbred Strains in Biomedical Research Book Review:

The Laboratory Mouse

The Laboratory Mouse
Author: Hans Hedrich
Publsiher: Academic Press
Total Pages: 868
Release: 2012-06-14
ISBN 10: 012382009X
ISBN 13: 9780123820099
Language: EN, FR, DE, ES & NL

The Laboratory Mouse Book Review:

The Laboratory Mouse, Second Edition is a comprehensive book written by international experts. With inclusions of the newly revised European standards on laboratory animals, this will be the most current, global authority on the care of mice in laboratory research. This well-illustrated edition offers new and updated chapters including immunology, viruses and parasites, behavior, enrichment and care standards of laboratory mice across the life sciences, medical and veterinary fields. Features four-color illustrations with complete instruction on mouse surgery, anatomy, behavior and care of the mouse in laboratory research Offers additional chapters on new mouse strains, phenotyping of strains, bacteria and parasites, and immunology Includes the newly revised EU standards on care, as well as, comparisons to standards and regulations in the US and other countries

A Practical Guide to the Histology of the Mouse

A Practical Guide to the Histology of the Mouse
Author: Cheryl L. Scudamore
Publsiher: John Wiley & Sons
Total Pages: 248
Release: 2013-12-24
ISBN 10: 1118789474
ISBN 13: 9781118789476
Language: EN, FR, DE, ES & NL

A Practical Guide to the Histology of the Mouse Book Review:

A Practical Guide to the Histology of the Mouse provides a full-colour atlas of mouse histology. Mouse models of disease are used extensively in biomedical research with many hundreds of new models being generated each year. Complete phenotypic analysis of all of these models can benefit from histologic review of the tissues. This book is aimed at veterinary and medical pathologists who are unfamiliar with mouse tissues and scientists who wish to evaluate their own mouse models. It provides practical guidance on the collection, sampling and analysis of mouse tissue samples in order to maximize the information that can be gained from these tissues. As well as illustrating the normal microscopic anatomy of the mouse, the book also describes and explains the common anatomic variations, artefacts associated with tissue collection and background lesions to help the scientist to distinguish these changes from experimentally- induced lesions. This will be an essential bench-side companion for researchers and practitioners looking for an accessible and well-illustrated guide to mouse pathology. Written by experienced pathologists and specifically tailored to the needs of scientists and histologists Full colour throughout Provides advice on sampling tissues, necropsy and recording data Includes common anatomic variations, background lesions and artefacts which will help non-experts understand whether histologic variations seen are part of the normal background or related to their experimental manipulation

Gnotobiotics

Gnotobiotics
Author: Trenton R Schoeb,Kathryn A Eaton
Publsiher: Academic Press
Total Pages: 428
Release: 2017-08-11
ISBN 10: 0128045833
ISBN 13: 9780128045831
Language: EN, FR, DE, ES & NL

Gnotobiotics Book Review:

Gnotobiotics summarizes and analyzes the research conducted on the use of gnotobiotes, providing detailed information regarding actual facility operation and derivation of gnotobiotic animals. In response to the development of new tools for microbiota and microbiome analysis, the increasing recognition of the various roles of microbiota in health and disease, and the consequent expanding demand for gnotobiotic animals for microbiota/microbiome related research, this volume collates the research of this expanding field into one definitive resource. Reviews and defines gnotobiotic animal species Analyzes microbiota in numerous contexts Presents detailed coverage of the protocols and operation of a gnotobiotic facility

The Mouse in Biomedical Research

The Mouse in Biomedical Research
Author: Anonim
Publsiher: Elsevier
Total Pages: 352
Release: 2006-12-04
ISBN 10: 9780080469065
ISBN 13: 008046906X
Language: EN, FR, DE, ES & NL

The Mouse in Biomedical Research Book Review:

History, Wild Mice, and Genetics, the first volume in the four volume set, The Mouse in Biomedical Research, provides information about the history, biology and genomics of the laboratory mouse (Mus musculus), as well as basic information on maintenance and use of mouse stocks. Mouse origins and relationships are covered in chapters on history, evolutionary taxonomy and wild mice. Genetics and genomics of the mouse are covered in chapters on genetic nomenclature, gene mapping, cytogenetics and the molecular organization of the mouse genome. Maintenance of laboratory mice is described in chapters on breeding systems for various types of strains and stocks and genetic monitoring. Use of the mouse as a model system for basic biomedical research is described in chapters on chemical mutagenesis, gene trapping, pharmacogenetics and embryo manipulation. The information in Volume 1 serves as a primer for scientists new to the field of mouse research.

Genetics in Wild Mice

Genetics in Wild Mice
Author: Kazuo Moriwaki,Toshihiko Shiroishi,Hiromichi Yonekowa
Publsiher: S Karger Ag
Total Pages: 333
Release: 1994
ISBN 10:
ISBN 13: UOM:39015034303019
Language: EN, FR, DE, ES & NL

Genetics in Wild Mice Book Review:

Use of Laboratory Animals in Biomedical and Behavioral Research

Use of Laboratory Animals in Biomedical and Behavioral Research
Author: National Research Council,Institute of Medicine,Institute for Laboratory Animal Research,Commission on Life Sciences,Committee on the Use of Laboratory Animals in Biomedical and Behavioral Research
Publsiher: National Academies Press
Total Pages: 112
Release: 1988-02-01
ISBN 10: 0309038391
ISBN 13: 9780309038393
Language: EN, FR, DE, ES & NL

Use of Laboratory Animals in Biomedical and Behavioral Research Book Review:

Scientific experiments using animals have contributed significantly to the improvement of human health. Animal experiments were crucial to the conquest of polio, for example, and they will undoubtedly be one of the keystones in AIDS research. However, some persons believe that the cost to the animals is often high. Authored by a committee of experts from various fields, this book discusses the benefits that have resulted from animal research, the scope of animal research today, the concerns of advocates of animal welfare, and the prospects for finding alternatives to animal use. The authors conclude with specific recommendations for more consistent government action.

Resource Sharing in Biomedical Research

Resource Sharing in Biomedical Research
Author: Institute of Medicine,Committee on Resource Sharing in Biomedical Research
Publsiher: National Academies Press
Total Pages: 104
Release: 1996-12-29
ISBN 10: 0309055822
ISBN 13: 9780309055826
Language: EN, FR, DE, ES & NL

Resource Sharing in Biomedical Research Book Review:

The United States is entering an era when, more than ever, the sharing of resources and information might be critical to scientific progress. Every dollar saved by avoiding duplication of efforts and by producing economies of scale will become increasingly important as federal funding enters an era of fiscal restraint. This book focuses on six diverse case studies that share materials or equipment with the scientific community at large: the American Type Culture Collection, the multinational coordinated Arabidopsis thaliana Genome Research Project, the Jackson Laboratory, the Washington Regional Primate Research Center, the Macromolecular Crystallography Resource at the Cornell High-Energy Synchrotron Source, and the Human Genome Center at Lawrence Livermore National Laboratory. The book also identifies common strengths and problems faced in the six cases, and presents a series of recommendations aimed at facilitating resource sharing in biomedical research.

Animal centric Care and Management

Animal centric Care and Management
Author: Dorte Bratbo Sørensen,Sylvie Cloutier,Brianna N. Gaskill
Publsiher: CRC Press
Total Pages: 190
Release: 2020-10-14
ISBN 10: 0429602057
ISBN 13: 9780429602054
Language: EN, FR, DE, ES & NL

Animal centric Care and Management Book Review:

The concept of the 3Rs (Refinement, Reduction and Replacement) has been used as a framework for improving the welfare of laboratory animals for the last half century. By establishing an animal-centric view on housing and management, Animal-centric Care and Management: Enhancing Refinement in Biomedical Research takes Russell and Burch’s definition of Refinement as "elimination of inhumanities" and goes further. Rather than fitting animals into experimental conditions, it encourages readers to adjust conditions to better meet the behavioral, emotional, physical, and physiological needs and preferences of the animals. The team of expert authors, from the fields of laboratory animal science, ethology, biology as well as animal training, provide ideas for creating housing conditions and handling procedures that induce, to the best of current abilities and knowledge, a long-term positive state of mind in the animals under our care. This book is written for animal caretakers, animal health technicians, researchers, animal facility managers, laboratory animal veterinarians, and anyone who engages in work with living experimental animals or is interested in the continuous improvement of laboratory animal welfare. This interdisciplinary guide will act as a catalyst, resulting in multiple viewpoints and fields collaborating to optimize laboratory animal welfare.

Morphological Mouse Phenotyping

Morphological Mouse Phenotyping
Author: Jesus Ruberte,Ana Carretero,Marc Navarro
Publsiher: Elsevier
Total Pages: 329
Release: 2017
ISBN 10: 0128128771
ISBN 13: 9780128128770
Language: EN, FR, DE, ES & NL

Morphological Mouse Phenotyping Book Review:

The Mouse in Biomedical Research

The Mouse in Biomedical Research
Author: Anonim
Publsiher: Unknown
Total Pages: 329
Release: 2005
ISBN 10:
ISBN 13: OCLC:226124695
Language: EN, FR, DE, ES & NL

The Mouse in Biomedical Research Book Review:

Basic Science Methods for Clinical Researchers

Basic Science Methods for Clinical Researchers
Author: Morteza Jalali,Francesca Yvonne Louise Saldanha,Mehdi Jalali
Publsiher: Academic Press
Total Pages: 382
Release: 2017-03-31
ISBN 10: 012803078X
ISBN 13: 9780128030783
Language: EN, FR, DE, ES & NL

Basic Science Methods for Clinical Researchers Book Review:

Basic Science Methods for Clinical Researchers addresses the specific challenges faced by clinicians without a conventional science background. The aim of the book is to introduce the reader to core experimental methods commonly used to answer questions in basic science research and to outline their relative strengths and limitations in generating conclusive data. This book will be a vital companion for clinicians undertaking laboratory-based science. It will support clinicians in the pursuit of their academic interests and in making an original contribution to their chosen field. In doing so, it will facilitate the development of tomorrow’s clinician scientists and future leaders in discovery science. Serves as a helpful guide for clinical researchers who lack a conventional science background Organized around research themes pertaining to key biological molecules, from genes, to proteins, cells, and model organisms Features protocols, techniques for troubleshooting common problems, and an explanation of the advantages and limitations of a technique in generating conclusive data Appendices provide resources for practical research methodology, including legal frameworks for using stem cells and animals in the laboratory, ethical considerations, and good laboratory practice (GLP)

The Mouse Brain in Stereotaxic Coordinates

The Mouse Brain in Stereotaxic Coordinates
Author: George Paxinos,Keith B. J. Franklin
Publsiher: Gulf Professional Publishing
Total Pages: 100
Release: 2004
ISBN 10: 9780125476409
ISBN 13: 012547640X
Language: EN, FR, DE, ES & NL

The Mouse Brain in Stereotaxic Coordinates Book Review:

The Mouse Brain in Stereotaxic Coordinates, Second Edition has been the acknowledged reference in this field since the publication of the first edition, and is now available in a Compact Edition. This will provide a more affordable option for students, as well as researchers needing an additional lab atlas. This version includes the coronal diagrams delineating the entire brain as well as the introductory text from the Deluxe edition. It is an essential reference for anyone studying the mouse brain or related species. * Includes 100 detailed diagrams of the coronal set delineating the entire mouse brain * Compact edition of the most comprehensive and accurate mouse brain atlas available * Contains minor updates and revisions from the full edition