The Mechanics of Inhaled Pharmaceutical Aerosols

The Mechanics of Inhaled Pharmaceutical Aerosols
Author: Warren H. Finlay
Publsiher: Academic Press
Total Pages: 302
Release: 2019-06-01
ISBN 10: 0081027869
ISBN 13: 9780081027868
Language: EN, FR, DE, ES & NL

The Mechanics of Inhaled Pharmaceutical Aerosols Book Review:

The Mechanics of Inhaled Pharmaceutical Aerosols: An Introduction, Second Edition provides a concise, but thorough exposition of fundamental concepts in the field of pharmaceutical aerosols. This revised edition will allow researchers in the field to gain a thorough understanding of the field from first principles, allowing them to understand, design, develop and improve inhaled pharmaceutical aerosol devices and therapies. Chapters consider mechanics and deposition, specifically in the respiratory tract, while others discuss the mechanics associated with the three existing types of pharmaceutical inhalation devices. This text will be very useful for academics and for courses taught at both undergraduate and graduate levels. Because of the interdisciplinary nature of this book, it will also serve a wide audience that includes engineers and scientists involved with inhaled aerosol therapies. Provides a concise, but thorough exposition of fundamental concepts in the field of pharmaceutical aerosols Allows researchers in the field to gain an up-to-date, thorough understanding of the field from first principles Introduces the pharmaceutical aerosols field to the many engineers and scientists entering the area

Exam Prep for The Mechanics of Inhaled Pharmaceutical Aerosols

Exam Prep for  The Mechanics of Inhaled Pharmaceutical Aerosols
Author: Anonim
Publsiher: Unknown
Total Pages: 329
Release: 2021
ISBN 10:
ISBN 13:
Language: EN, FR, DE, ES & NL

Exam Prep for The Mechanics of Inhaled Pharmaceutical Aerosols Book Review:

Pharmaceutical Inhalation Aerosol Technology Second Edition

Pharmaceutical Inhalation Aerosol Technology  Second Edition
Author: Anthony J. Hickey
Publsiher: CRC Press
Total Pages: 288
Release: 2003-09-03
ISBN 10: 9780824756642
ISBN 13: 0824756649
Language: EN, FR, DE, ES & NL

Pharmaceutical Inhalation Aerosol Technology Second Edition Book Review:

This thoroughly revised and expanded reference provides authoritative discussions on the physiologic, pharmacologic, metabolic, molecular, cellular and physicochemical factors, influencing the efficacy and utilization of pharmaceutical aerosol. It analyzes the latest science and developments in the generation, administration and characterization of these compounds, showcasing current clinical applications, the efficiency and limitations of major aerosol products and emerging aerosol therapies impacting the field.

Inhaled Pharmaceutical Product Development Perspectives

Inhaled Pharmaceutical Product Development Perspectives
Author: Anthony J. Hickey
Publsiher: Elsevier
Total Pages: 110
Release: 2017-11-23
ISBN 10: 0128123362
ISBN 13: 9780128123362
Language: EN, FR, DE, ES & NL

Inhaled Pharmaceutical Product Development Perspectives Book Review:

Inhaled Pharmaceutical Product Development Perspectives: Challenges and Opportunities describes methods and procedures for consideration when developing inhaled pharmaceuticals, while commenting on product development strategies and their suitability to support regulatory submission. It bridges the gap between the aspirations of scientists invested in new technology development and the requirements that must be met for any new product. The book brings together emerging analytical and inhalation technologies, providing perspectives that illuminate formulation and device design, development, regulatory compliance, and practice. Focusing on underlying scientific and technical principles known to be acceptable from the current regulatory perspective, this monograph will remain useful as a high-level guide to inhaled product development for the foreseeable future. Discusses development strategies and best practices in the context of regulatory requirements Written by a broadly qualified expert drawing on the knowledge and critical opinions of key individuals in the field Includes a foreword by Charles G. Thiel

Inhalation Aerosols

Inhalation Aerosols
Author: Anthony J. Hickey,Heidi M. Mansour
Publsiher: CRC Press
Total Pages: 417
Release: 2019-03-21
ISBN 10: 1351660519
ISBN 13: 9781351660518
Language: EN, FR, DE, ES & NL

Inhalation Aerosols Book Review:

Inhalation aerosols continue to be the basis for successful lung therapy for several diseases, with therapeutic strategies and the range of technology significantly evolving in recent years. In response, this third edition takes a new approach to reflect the close integration of technology with its application. After briefly presenting the general considerations that apply to aerosol inhalation, the central section of the book uses the focus on disease and therapeutic agents to illustrate the application of specific technologies. The final integrated strategies section draws the major points from the applications for disease targets and drug products.

Controlled Pulmonary Drug Delivery

Controlled Pulmonary Drug Delivery
Author: Hugh D.C. Smyth,Anthony J. Hickey
Publsiher: Springer Science & Business Media
Total Pages: 558
Release: 2011-06-24
ISBN 10: 9781441997456
ISBN 13: 1441997458
Language: EN, FR, DE, ES & NL

Controlled Pulmonary Drug Delivery Book Review:

The pace of new research and level of innovation repeatedly introduced into the field of drug delivery to the lung is surprising given its state of maturity since the introduction of the pressurized metered dose inhaler over a half a century ago. It is clear that our understanding of pulmonary drug delivery has now evolved to the point that inhalation aerosols can be controlled both spatially and temporally to optimize their biological effects. These abilities include controlling lung deposition, by adopting formulation strategies or device technologies, and controlling drug uptake and release through sophisticated particle technologies. The large number of contributions to the scientific literature and variety of excellent texts published in recent years is evidence for the continued interest in pulmonary drug delivery research. This reference text endeavors to bring together the fundamental theory and practice of controlled drug delivery to the airways that is unavailable elsewhere. Collating and synthesizing the material in this rapidly evolving field presented a challenge and ultimately a sense of achievement that is hopefully reflected in the content of the volume.

Aerosol Science

Aerosol Science
Author: Ian Colbeck,Mihalis Lazaridis
Publsiher: John Wiley & Sons
Total Pages: 496
Release: 2014-01-30
ISBN 10: 1118675355
ISBN 13: 9781118675359
Language: EN, FR, DE, ES & NL

Aerosol Science Book Review:

Aerosols influence many areas of our daily life. They are at the core of environmental problems such as global warming, photochemical smog and poor air quality. They can also have diverse effects on human health, where exposure occurs in both outdoor and indoor environments. However, aerosols can have beneficial effects too; the delivery of drugs to the lungs, the delivery of fuels for combustion and the production of nanomaterials all rely on aerosols. Advances in particle measurement technologies have made it possible to take advantage of rapid changes in both particle size and concentration. Likewise, aerosols can now be produced in a controlled fashion. Reviewing many technological applications together with the current scientific status of aerosol modelling and measurements, this book includes: • Satellite aerosol remote sensing • The effects of aerosols on climate change • Air pollution and health • Pharmaceutical aerosols and pulmonary drug delivery • Bioaerosols and hospital infections • Particle emissions from vehicles • The safety of emerging nanomaterials • Radioactive aerosols: tracers of atmospheric processes With the importance of this topic brought to the public’s attention after the eruption of the Icelandic volcano Eyjafjallajökull, this book provides a timely, concise and accessible overview of the many facets of aerosol science.

Aerosols Handbook

Aerosols Handbook
Author: Lev S. Ruzer,Naomi H. Harley
Publsiher: CRC Press
Total Pages: 728
Release: 2004-12-28
ISBN 10: 9780203493182
ISBN 13: 0203493184
Language: EN, FR, DE, ES & NL

Aerosols Handbook Book Review:

As more attention is dedicated to understanding the occupational health risks associated with the industrial manufacture and use of nanotechnology, Aerosols Handbook: Measurement, Dosimetry, and Health Effects is a timely presentation of time-tested research in the field of aerosol science. The book covers a multitude of topics in indoor, outdoor,

Inhaled Medicines

Inhaled Medicines
Author: Stavros Kassinos,Per Bäckman,Joy Conway,Anthony J. J. Hickey
Publsiher: Academic Press
Total Pages: 438
Release: 2021-02-05
ISBN 10: 0128149744
ISBN 13: 9780128149744
Language: EN, FR, DE, ES & NL

Inhaled Medicines Book Review:

Inhaled medicines are widely used to treat pulmonary and systemic diseases. The efficacy and safety of these medicines can be influenced by the deposited fraction, the regional deposition pattern within the lungs and by post-depositional events such as drug dissolution, absorption and clearance from the lungs. Optimizing performance of treatments thus requires that we understand and are able to quantify these product and drug attributes. Inhaled Medicines: Optimizing Development through Integration of In Silico, In Vitro and In Vivo Approaches explores the current state of the art with respect to inhalation drug delivery, technologies available to assess product performance, and novel in silico methods now available to link in vitro product performance to clinical performance. Recent developments in the latter field, especially the prospect of integration of three-dimensional Computational Fluid Particle Methods (3D-CFPD) with physiologically based pharmacokinetic (PBPK models), unlocks the potential for in silico population studies that can help inform and optimize treatment and product development strategies. In this highly multidisciplinary field, where progress occurs at the intersection of several disciplines of engineering and science, this work aims to integrate current knowledge and understanding and to articulate a clear vision for future developments. ? Considers the healthcare needs driving the field, and where inhaled drugs could have the maximum impact ? Gives a concise account of the state of the art in key areas and technologies such as device and formulation technologies, clinically relevant in vitro performance assessment, medical imaging, as well as in silico modelling and simulation ? Articulates how the combination of in vitro product performance data, medical imaging and simulations technologies in the framework of large scale in silico pre-clinical trials could revolutionize the field ? Provides systematic and thorough referencing to sources offering a more-in-depth analysis of technical issues

Good Cascade Impactor Practices AIM and EDA for Orally Inhaled Products

Good Cascade Impactor Practices  AIM and EDA for Orally Inhaled Products
Author: Terrence P. Tougas,Jolyon P. Mitchell,Svetlana A. Lyapustina
Publsiher: Springer Science & Business Media
Total Pages: 442
Release: 2013-04-10
ISBN 10: 1461462967
ISBN 13: 9781461462965
Language: EN, FR, DE, ES & NL

Good Cascade Impactor Practices AIM and EDA for Orally Inhaled Products Book Review:

The purpose of this publication is to introduce a new, simpler and more effective way in which to interpret pharmaceutical aerosol particle size data from orally inhaled products (OIPs). Currently, the compendial and regulatory requirements dictate the need for measurements by full resolution multi-stage cascade impactor (CI), a process that is demanding for the operator, time consuming, prone to experimental error, and challenging for method transfers from one laboratory to another. Furthermore, we shall show that the current practice of reducing information from mass-weighted aerodynamic particle size distribution (APSD) measurements through the use of CI stage groupings is not the most effective decision-making tool for OIP quality control (QC) in comparison with newly introduced, mutually-independent efficient data analysis (EDA) metrics that can be derived either from full resolution or abbreviated impactor measurements (AIM).

Optimization of Aerosol Drug Delivery

Optimization of Aerosol Drug Delivery
Author: Leon Gradon,J.C. Marijnissen
Publsiher: Springer Science & Business Media
Total Pages: 315
Release: 2003-11-30
ISBN 10: 9781402016516
ISBN 13: 1402016514
Language: EN, FR, DE, ES & NL

Optimization of Aerosol Drug Delivery Book Review:

Aerosol therapy has significantly improved the treatment of a variety of respiratory diseases. Besides the treatment of respiratory diseases there is currently also a great interest to use the lungs as a portal to introduce drugs for systemic therapy. The success of therapy with the application of aerosolized medicaments depends on the possibility to deliver the proper amount of drug to the appropriate sites in the respiratory system, thus limiting the side effects to a minimum. Aerosolized delivery of drugs to the lung is optimized if, for a given chemical composition of a medicine, the target of deposition and the required mass of drug to be deposited are precisely defined. The next step is the specification of the number of respirable particles or droplets, to be generated by appropriate devices. Another very important factor for successful aerosol therapy is the condition of the patient coupled with his or her inhalation technique.

Aerosol Measurement

Aerosol Measurement
Author: Pramod Kulkarni,Paul A. Baron,Klaus Willeke
Publsiher: John Wiley & Sons
Total Pages: 900
Release: 2011-09-09
ISBN 10: 9781118001677
ISBN 13: 1118001672
Language: EN, FR, DE, ES & NL

Aerosol Measurement Book Review:

Aerosol Measurement: Principles, Techniques, and Applications Third Edition is the most detailed treatment available of the latest aerosol measurement methods. Drawing on the know-how of numerous expert contributors; it provides a solid grasp of measurement fundamentals and practices a wide variety of aerosol applications. This new edition is updated to address new and developing applications of aerosol measurement, including applications in environmental health, atmospheric science, climate change, air pollution, public health, nanotechnology, particle and powder technology, pharmaceutical research and development, clean room technology (integrated circuit manufacture), and nuclear waste management.

Respiratory Drug Delivery 1989

Respiratory Drug Delivery  1989
Author: Peter R. Byron
Publsiher: CRC Press
Total Pages: 276
Release: 2018-04-20
ISBN 10: 1351358014
ISBN 13: 9781351358019
Language: EN, FR, DE, ES & NL

Respiratory Drug Delivery 1989 Book Review:

The focus of this book is on subjects related to drug delivery to the lung. The text spans topics from aerosol deposition through pharmaceutical chemistry and formulation to the final clinical evaluation of pharmaceutical products. Utilizing a multi-disciplinary approach, the chapters consider toxicology from the point of view of drugs and pharmaceutical excipients used in aerosols.

Aerosols

Aerosols
Author: Konstantin Volkov
Publsiher: BoD – Books on Demand
Total Pages: 206
Release: 2016-12-28
ISBN 10: 9535128434
ISBN 13: 9789535128434
Language: EN, FR, DE, ES & NL

Aerosols Book Review:

Aerosols have a significant impact on technological processes and human activities. In many cases, aerosols are at the core of human health, environmental and technological problems (climate change and air quality). However, aerosols can be successfully used in industry and technology (new materials, fire suppression and fuel delivery). The current scientific status of aerosol modelling and simulation and measurements and some advances in computational techniques, particle measurement technologies and practical applications of aerosols are reviewed and considered in this book. This book also includes a number of case studies focused on analysis of optical thickness and air quality in various regions.

Delivery Systems for Tuberculosis Prevention and Treatment

Delivery Systems for Tuberculosis Prevention and Treatment
Author: Anthony J. Hickey
Publsiher: John Wiley & Sons
Total Pages: 456
Release: 2016-08-25
ISBN 10: 1118943201
ISBN 13: 9781118943205
Language: EN, FR, DE, ES & NL

Delivery Systems for Tuberculosis Prevention and Treatment Book Review:

Provides a review of novel pharmaceutical approaches for Tuberculosis drugs Presents a novel perspective on tuberculosis prevention and treatment Considers the nature of disease, immunological responses, vaccine and drug delivery, disposition and response Multidisciplinary appeal, with contributions from microbiology, immunology, molecular biology, pharmaceutics, pharmacokinetics, chemical and mechanical engineering

Inhalation Toxicology

Inhalation Toxicology
Author: Harry Salem,Sidney A. Katz
Publsiher: CRC Press
Total Pages: 1056
Release: 2005-12-22
ISBN 10: 1420037307
ISBN 13: 9781420037302
Language: EN, FR, DE, ES & NL

Inhalation Toxicology Book Review:

Written by internationally recognized scientists from academic, industrial, and governmental sectors, Inhalation Toxicology, Second Edition details the methods and materials used in the theoretical and applied aspects of inhalation toxicology. The editors emphasize the relationship between the respiratory system and toxicology of inhaled substances and examine methods and measurements for improving our understanding of the basic mechanisms of effects. The book delineates key issues in the field such as regulatory aspects of exposure and testing, testing equipment and methods, biomarkers, pathology, allergies and immunology, irritation of the respiratory tract, and risk assessment. It covers the inhalation of bioaerosols and toxins, ranging from anthrax to household molds as well as genomics, proteomics, and low-level exposure toxicants such as tobacco smoke and chemical warfare agents. Highlights include coverage of the Acute Exposure Guidelines and Emergence Response Guidelines and recent changes in the European and American guidelines for testing procedures. The book focuses on key issues associated with airborne substances and provides critical reviews of the latest advances. Presenting sophisticated concepts in a readable, accessible format, the book distills the latest information into practical knowledge.

Design of Controlled Release Drug Delivery Systems

Design of Controlled Release Drug Delivery Systems
Author: Xiaoling Li
Publsiher: McGraw Hill Professional
Total Pages: 435
Release: 2005-11-24
ISBN 10: 0071588833
ISBN 13: 9780071588836
Language: EN, FR, DE, ES & NL

Design of Controlled Release Drug Delivery Systems Book Review:

The goal of every drug delivery system is to deliver the precise amount of a drug at a pre-programmed rate to the desired location in order to achieve the drug level necessary for the treatment. An essential guide for biomedical engineers and pharmaceutical designers, this resource combines physicochemical principles with physiological processes to facilitate the design of systems that will deliver medication at the time and place it is most needed.

Pharmaceutical Inhalation Aerosol Technology Third Edition

Pharmaceutical Inhalation Aerosol Technology  Third Edition
Author: Anthony J. Hickey,Sandro R. da Rocha
Publsiher: CRC Press
Total Pages: 730
Release: 2019-03-26
ISBN 10: 0429619561
ISBN 13: 9780429619564
Language: EN, FR, DE, ES & NL

Pharmaceutical Inhalation Aerosol Technology Third Edition Book Review:

This fully revised and updated third edition of Pharmaceutical Inhalation Aerosol Technology encompasses the scientific and technical foundation for the rationale, design, componentry, assembly and quality performance metrics of therapeutic inhalers in their delivery of pharmaceutical aerosols to treat symptoms or the underlying causes of disease. It focuses on the importance of pharmaceutical engineering as a foundational element of all inhaler products and their application to pulmonary drug delivery. The expanded scope considers previously unaddressed aspects of pharmaceutical inhalation aerosol technology and the patient interface by including aerosol delivery, lung deposition and clearance that are used as measures of effective dose delivery.

Drug Delivery to the Lung

Drug Delivery to the Lung
Author: Hans Bisgaard,Chris O'Callaghan,Gerald C. Smaldone
Publsiher: CRC Press
Total Pages: 536
Release: 2001-10-02
ISBN 10: 9780824741976
ISBN 13: 0824741978
Language: EN, FR, DE, ES & NL

Drug Delivery to the Lung Book Review:

This book focuses on the aerosol treatment of lung diseases, recent improvements in the understanding of proper dosage, and major innovations in device technology applied to clinical practice. Examines the behavior of inspired spherical particles in the respiratory tract! Featuring over 1300 references, drawings, tables, photographs,

Inhaler Devices

Inhaler Devices
Author: Polina Prokopovich
Publsiher: Elsevier
Total Pages: 192
Release: 2013-04-23
ISBN 10: 0857098691
ISBN 13: 9780857098696
Language: EN, FR, DE, ES & NL

Inhaler Devices Book Review:

Given their direct impact on the health and quality of life for millions, inhalers represent a major turning point in the history of modern medicine. Inhaler devices: Fundamentals, design and drug delivery provides readers with an introduction to the fundamentals of inhaler technology, with a comprehensive discussion of the history of inhalers as well as a discussion on current research and development. Part one discusses the fundamentals and development of inhaler devices as well as drug formulations for inhalers. The treatment of asthma is also discussed. Part two reviews recent developments in drug formulation and nanotechnology for inhaler devices, emerging inhaler technology and possible future trends. Inhaler devices: Fundamentals, design and drug delivery is an essential design guide for good industrial practice, and will be an invaluable resource for those researching and treating conditions such as asthma; and those developing and manufacturing inhalation devices. Introduces the fundamentals of inhaler technology Discusses the history of inhalers as well as current research and development as well as possible future trends Considers the development of inhaler devices, drug formulations and discusses the treatment of asthma