The Mechanics of Inhaled Pharmaceutical Aerosols

The Mechanics of Inhaled Pharmaceutical Aerosols
Author: Warren H. Finlay
Publsiher: Academic Press
Total Pages: 302
Release: 2019-06-01
ISBN 10: 0081027869
ISBN 13: 9780081027868
Language: EN, FR, DE, ES & NL

The Mechanics of Inhaled Pharmaceutical Aerosols Book Review:

The Mechanics of Inhaled Pharmaceutical Aerosols: An Introduction, Second Edition provides a concise, but thorough exposition of fundamental concepts in the field of pharmaceutical aerosols. This revised edition will allow researchers in the field to gain a thorough understanding of the field from first principles, allowing them to understand, design, develop and improve inhaled pharmaceutical aerosol devices and therapies. Chapters consider mechanics and deposition, specifically in the respiratory tract, while others discuss the mechanics associated with the three existing types of pharmaceutical inhalation devices. This text will be very useful for academics and for courses taught at both undergraduate and graduate levels. Because of the interdisciplinary nature of this book, it will also serve a wide audience that includes engineers and scientists involved with inhaled aerosol therapies. Provides a concise, but thorough exposition of fundamental concepts in the field of pharmaceutical aerosols Allows researchers in the field to gain an up-to-date, thorough understanding of the field from first principles Introduces the pharmaceutical aerosols field to the many engineers and scientists entering the area

Pharmaceutical Inhalation Aerosol Technology Second Edition

Pharmaceutical Inhalation Aerosol Technology  Second Edition
Author: Anthony J. Hickey
Publsiher: CRC Press
Total Pages: 288
Release: 2003-09-03
ISBN 10: 0824756649
ISBN 13: 9780824756642
Language: EN, FR, DE, ES & NL

Pharmaceutical Inhalation Aerosol Technology Second Edition Book Review:

This thoroughly revised and expanded reference provides authoritative discussions on the physiologic, pharmacologic, metabolic, molecular, cellular and physicochemical factors, influencing the efficacy and utilization of pharmaceutical aerosol. It analyzes the latest science and developments in the generation, administration and characterization of these compounds, showcasing current clinical applications, the efficiency and limitations of major aerosol products and emerging aerosol therapies impacting the field.

Inhalation Aerosols

Inhalation Aerosols
Author: Anthony J. Hickey,Heidi M. Mansour
Publsiher: CRC Press
Total Pages: 417
Release: 2019-03-21
ISBN 10: 1351660519
ISBN 13: 9781351660518
Language: EN, FR, DE, ES & NL

Inhalation Aerosols Book Review:

Inhalation aerosols continue to be the basis for successful lung therapy for several diseases, with therapeutic strategies and the range of technology significantly evolving in recent years. In response, this third edition takes a new approach to reflect the close integration of technology with its application. After briefly presenting the general considerations that apply to aerosol inhalation, the central section of the book uses the focus on disease and therapeutic agents to illustrate the application of specific technologies. The final integrated strategies section draws the major points from the applications for disease targets and drug products.

Aerosol Science

Aerosol Science
Author: Ian Colbeck,Mihalis Lazaridis
Publsiher: John Wiley & Sons
Total Pages: 496
Release: 2014-01-30
ISBN 10: 1118675355
ISBN 13: 9781118675359
Language: EN, FR, DE, ES & NL

Aerosol Science Book Review:

Aerosols influence many areas of our daily life. They are at the core of environmental problems such as global warming, photochemical smog and poor air quality. They can also have diverse effects on human health, where exposure occurs in both outdoor and indoor environments. However, aerosols can have beneficial effects too; the delivery of drugs to the lungs, the delivery of fuels for combustion and the production of nanomaterials all rely on aerosols. Advances in particle measurement technologies have made it possible to take advantage of rapid changes in both particle size and concentration. Likewise, aerosols can now be produced in a controlled fashion. Reviewing many technological applications together with the current scientific status of aerosol modelling and measurements, this book includes: • Satellite aerosol remote sensing • The effects of aerosols on climate change • Air pollution and health • Pharmaceutical aerosols and pulmonary drug delivery • Bioaerosols and hospital infections • Particle emissions from vehicles • The safety of emerging nanomaterials • Radioactive aerosols: tracers of atmospheric processes With the importance of this topic brought to the public’s attention after the eruption of the Icelandic volcano Eyjafjallajökull, this book provides a timely, concise and accessible overview of the many facets of aerosol science.

Inhaled Medicines

Inhaled Medicines
Author: Stavros Kassinos,Per Bäckman,Joy Conway,Anthony J. J. Hickey
Publsiher: Academic Press
Total Pages: 438
Release: 2021-02-05
ISBN 10: 0128149744
ISBN 13: 9780128149744
Language: EN, FR, DE, ES & NL

Inhaled Medicines Book Review:

Inhaled medicines are widely used to treat pulmonary and systemic diseases. The efficacy and safety of these medicines can be influenced by the deposited fraction, the regional deposition pattern within the lungs and by post-depositional events such as drug dissolution, absorption and clearance from the lungs. Optimizing performance of treatments thus requires that we understand and are able to quantify these product and drug attributes. Inhaled Medicines: Optimizing Development through Integration of In Silico, In Vitro and In Vivo Approaches explores the current state of the art with respect to inhalation drug delivery, technologies available to assess product performance, and novel in silico methods now available to link in vitro product performance to clinical performance. Recent developments in the latter field, especially the prospect of integration of three-dimensional Computational Fluid Particle Methods (3D-CFPD) with physiologically based pharmacokinetic (PBPK models), unlocks the potential for in silico population studies that can help inform and optimize treatment and product development strategies. In this highly multidisciplinary field, where progress occurs at the intersection of several disciplines of engineering and science, this work aims to integrate current knowledge and understanding and to articulate a clear vision for future developments. ? Considers the healthcare needs driving the field, and where inhaled drugs could have the maximum impact ? Gives a concise account of the state of the art in key areas and technologies such as device and formulation technologies, clinically relevant in vitro performance assessment, medical imaging, as well as in silico modelling and simulation ? Articulates how the combination of in vitro product performance data, medical imaging and simulations technologies in the framework of large scale in silico pre-clinical trials could revolutionize the field ? Provides systematic and thorough referencing to sources offering a more-in-depth analysis of technical issues

Aerosol Measurement

Aerosol Measurement
Author: Pramod Kulkarni,Paul A. Baron,Klaus Willeke
Publsiher: John Wiley & Sons
Total Pages: 900
Release: 2011-09-09
ISBN 10: 9781118001677
ISBN 13: 1118001672
Language: EN, FR, DE, ES & NL

Aerosol Measurement Book Review:

Aerosol Measurement: Principles, Techniques, and Applications Third Edition is the most detailed treatment available of the latest aerosol measurement methods. Drawing on the know-how of numerous expert contributors; it provides a solid grasp of measurement fundamentals and practices a wide variety of aerosol applications. This new edition is updated to address new and developing applications of aerosol measurement, including applications in environmental health, atmospheric science, climate change, air pollution, public health, nanotechnology, particle and powder technology, pharmaceutical research and development, clean room technology (integrated circuit manufacture), and nuclear waste management.

Good Cascade Impactor Practices AIM and EDA for Orally Inhaled Products

Good Cascade Impactor Practices  AIM and EDA for Orally Inhaled Products
Author: Terrence P. Tougas,Jolyon P. Mitchell,Svetlana A. Lyapustina
Publsiher: Springer Science & Business Media
Total Pages: 442
Release: 2013-04-10
ISBN 10: 1461462967
ISBN 13: 9781461462965
Language: EN, FR, DE, ES & NL

Good Cascade Impactor Practices AIM and EDA for Orally Inhaled Products Book Review:

The purpose of this publication is to introduce a new, simpler and more effective way in which to interpret pharmaceutical aerosol particle size data from orally inhaled products (OIPs). Currently, the compendial and regulatory requirements dictate the need for measurements by full resolution multi-stage cascade impactor (CI), a process that is demanding for the operator, time consuming, prone to experimental error, and challenging for method transfers from one laboratory to another. Furthermore, we shall show that the current practice of reducing information from mass-weighted aerodynamic particle size distribution (APSD) measurements through the use of CI stage groupings is not the most effective decision-making tool for OIP quality control (QC) in comparison with newly introduced, mutually-independent efficient data analysis (EDA) metrics that can be derived either from full resolution or abbreviated impactor measurements (AIM).

Transient Deposition of Particles with Applications to Inhaled Pharmaceutical Aerosols

Transient Deposition of Particles with Applications to Inhaled Pharmaceutical Aerosols
Author: Philip S. Ophus
Publsiher: Unknown
Total Pages: 135
Release: 2011
ISBN 10: 1928374650XXX
ISBN 13: OCLC:711789535
Language: EN, FR, DE, ES & NL

Transient Deposition of Particles with Applications to Inhaled Pharmaceutical Aerosols Book Review:

Aerosols Handbook

Aerosols Handbook
Author: Lev S. Ruzer,Naomi H. Harley
Publsiher: CRC Press
Total Pages: 728
Release: 2004-12-28
ISBN 10: 9780203493182
ISBN 13: 0203493184
Language: EN, FR, DE, ES & NL

Aerosols Handbook Book Review:

As more attention is dedicated to understanding the occupational health risks associated with the industrial manufacture and use of nanotechnology, Aerosols Handbook: Measurement, Dosimetry, and Health Effects is a timely presentation of time-tested research in the field of aerosol science. The book covers a multitude of topics in indoor, outdoor,

Pharmaceutical Inhalation Aerosol Technology Third Edition

Pharmaceutical Inhalation Aerosol Technology  Third Edition
Author: Anthony J. Hickey,Sandro R. da Rocha
Publsiher: CRC Press
Total Pages: 730
Release: 2019-03-26
ISBN 10: 0429619561
ISBN 13: 9780429619564
Language: EN, FR, DE, ES & NL

Pharmaceutical Inhalation Aerosol Technology Third Edition Book Review:

This fully revised and updated third edition of Pharmaceutical Inhalation Aerosol Technology encompasses the scientific and technical foundation for the rationale, design, componentry, assembly and quality performance metrics of therapeutic inhalers in their delivery of pharmaceutical aerosols to treat symptoms or the underlying causes of disease. It focuses on the importance of pharmaceutical engineering as a foundational element of all inhaler products and their application to pulmonary drug delivery. The expanded scope considers previously unaddressed aspects of pharmaceutical inhalation aerosol technology and the patient interface by including aerosol delivery, lung deposition and clearance that are used as measures of effective dose delivery.

Controlled Pulmonary Drug Delivery

Controlled Pulmonary Drug Delivery
Author: Hugh D.C. Smyth,Anthony J. Hickey
Publsiher: Springer Science & Business Media
Total Pages: 558
Release: 2011-06-24
ISBN 10: 9781441997456
ISBN 13: 1441997458
Language: EN, FR, DE, ES & NL

Controlled Pulmonary Drug Delivery Book Review:

The pace of new research and level of innovation repeatedly introduced into the field of drug delivery to the lung is surprising given its state of maturity since the introduction of the pressurized metered dose inhaler over a half a century ago. It is clear that our understanding of pulmonary drug delivery has now evolved to the point that inhalation aerosols can be controlled both spatially and temporally to optimize their biological effects. These abilities include controlling lung deposition, by adopting formulation strategies or device technologies, and controlling drug uptake and release through sophisticated particle technologies. The large number of contributions to the scientific literature and variety of excellent texts published in recent years is evidence for the continued interest in pulmonary drug delivery research. This reference text endeavors to bring together the fundamental theory and practice of controlled drug delivery to the airways that is unavailable elsewhere. Collating and synthesizing the material in this rapidly evolving field presented a challenge and ultimately a sense of achievement that is hopefully reflected in the content of the volume.

Advances in Pulmonary Drug Delivery

Advances in Pulmonary Drug Delivery
Author: Philip Chi Lip Kwok,Hak-Kim Chan
Publsiher: CRC Press
Total Pages: 246
Release: 2016-12-19
ISBN 10: 131531195X
ISBN 13: 9781315311951
Language: EN, FR, DE, ES & NL

Advances in Pulmonary Drug Delivery Book Review:

The respiratory tract has been used to deliver biologically active chemicals into the human body for centuries. However, the lungs are complex in their anatomy and physiology, which poses challenges to drug delivery. Inhaled formulations are generally more sophisticated than those for oral and parenteral administration. Pulmonary drug development is therefore a highly specialized area because of its many unique issues and challenges. Rapid progress is being made and offers novel solutions to existing treatment problems. Advances in Pulmonary Drug Delivery highlights the latest developments in this field.

Aerosol Technology

Aerosol Technology
Author: William C. Hinds
Publsiher: John Wiley & Sons
Total Pages: 504
Release: 2012-12-06
ISBN 10: 1118591976
ISBN 13: 9781118591970
Language: EN, FR, DE, ES & NL

Aerosol Technology Book Review:

The #1 guide to aerosol science and technology -now better than ever Since 1982, Aerosol Technology has been the text of choice among students and professionals who need to acquire a thorough working knowledge of modern aerosol theory and applications. Now revised to reflect the considerable advances that have been made over the past seventeen years across a broad spectrum of aerosol-related application areas - from occupational hygiene and biomedical technology to microelectronics and pollution control -this new edition includes: * A chapter on bioaerosols * New sections on resuspension, transport losses, respiratory deposition models, and fractal characterization of particles * Expanded coverage of atmospheric aerosols, including background aerosols and urban aerosols * A section on the impact of aerosols on global warming and ozone depletion. Aerosol Technology, Second Edition also features dozens of new, fully worked examples drawn from a wide range of industrial and research settings, plus new chapter-end practice problems to help readers master the material quickly.

Handbook of Atomization and Sprays

Handbook of Atomization and Sprays
Author: Nasser Ashgriz
Publsiher: Springer Science & Business Media
Total Pages: 935
Release: 2011-02-18
ISBN 10: 9781441972644
ISBN 13: 1441972641
Language: EN, FR, DE, ES & NL

Handbook of Atomization and Sprays Book Review:

Atomization and sprays are used in a wide range of industries: mechanical, chemical, aerospace, and civil engineering; material science and metallurgy; food; pharmaceutical, forestry, environmental protection; medicine; agriculture; meteorology and others. Some specific applications are spray combustion in furnaces, gas turbines and rockets, spray drying and cooling, air conditioning, powdered metallurgy, spray painting and coating, inhalation therapy, and many others. The Handbook of Atomization and Sprays will bring together the fundamental and applied material from all fields into one comprehensive source. Subject areas included in the reference are droplets, theoretical models and numerical simulations, phase Doppler particle analysis, applications, devices and more.

Rhinosinusitis

Rhinosinusitis
Author: Balwant Singh Gendeh,Mirjana Turkalj
Publsiher: BoD – Books on Demand
Total Pages: 180
Release: 2019-12-04
ISBN 10: 1789840430
ISBN 13: 9781789840438
Language: EN, FR, DE, ES & NL

Rhinosinusitis Book Review:

This book highlights five different sections of rhinosinusitis, namely allergic rhinitis, sinusitis, dental-related sinusitis, one airway disease, and surgical techniques in sino-nasal diseases. It incorporates new clinical and research developments as well as future perspectives in the ever-expanding upper and lower airway problems. I dedicate this book to those who provide continued research, high-quality clinical observations, and care, as well as selfless teaching and publications to advance knowledge in airway problems. ENT surgeons, rhinologists, allergologists, immunologists, pulmonologists, postgraduates, researches, trainees, and general practitioners with special interest in one airway disease will find this book useful and interesting.

Delivery Systems for Tuberculosis Prevention and Treatment

Delivery Systems for Tuberculosis Prevention and Treatment
Author: Anthony J. Hickey
Publsiher: John Wiley & Sons
Total Pages: 456
Release: 2016-08-25
ISBN 10: 1118943201
ISBN 13: 9781118943205
Language: EN, FR, DE, ES & NL

Delivery Systems for Tuberculosis Prevention and Treatment Book Review:

Provides a review of novel pharmaceutical approaches for Tuberculosis drugs Presents a novel perspective on tuberculosis prevention and treatment Considers the nature of disease, immunological responses, vaccine and drug delivery, disposition and response Multidisciplinary appeal, with contributions from microbiology, immunology, molecular biology, pharmaceutics, pharmacokinetics, chemical and mechanical engineering

Drug Delivery to the Lung

Drug Delivery to the Lung
Author: Hans Bisgaard,Chris O'Callaghan,Gerald C. Smaldone
Publsiher: CRC Press
Total Pages: 536
Release: 2001-10-02
ISBN 10: 9780824741976
ISBN 13: 0824741978
Language: EN, FR, DE, ES & NL

Drug Delivery to the Lung Book Review:

This book focuses on the aerosol treatment of lung diseases, recent improvements in the understanding of proper dosage, and major innovations in device technology applied to clinical practice. Examines the behavior of inspired spherical particles in the respiratory tract! Featuring over 1300 references, drawings, tables, photographs,

Aerosols

Aerosols
Author: Konstantin Volkov
Publsiher: BoD – Books on Demand
Total Pages: 206
Release: 2016-12-28
ISBN 10: 9535128434
ISBN 13: 9789535128434
Language: EN, FR, DE, ES & NL

Aerosols Book Review:

Aerosols have a significant impact on technological processes and human activities. In many cases, aerosols are at the core of human health, environmental and technological problems (climate change and air quality). However, aerosols can be successfully used in industry and technology (new materials, fire suppression and fuel delivery). The current scientific status of aerosol modelling and simulation and measurements and some advances in computational techniques, particle measurement technologies and practical applications of aerosols are reviewed and considered in this book. This book also includes a number of case studies focused on analysis of optical thickness and air quality in various regions.

Characterization of Pharmaceutical Nano and Microsystems

Characterization of Pharmaceutical Nano  and Microsystems
Author: Leena Peltonen
Publsiher: John Wiley & Sons
Total Pages: 416
Release: 2020-10-16
ISBN 10: 1119414032
ISBN 13: 9781119414032
Language: EN, FR, DE, ES & NL

Characterization of Pharmaceutical Nano and Microsystems Book Review:

Learn about the analytical tools used to characterize particulate drug delivery systems with this comprehensive overview Edited by a leading expert in the field, Characterization of Pharmaceutical Nano- and Microsystems provides a complete description of the analytical techniques used to characterize particulate drug systems on the micro- and nanoscale. The book offers readers a full understanding of the basic physicochemical characteristics, material properties and differences between micro- and nanosystems. It explains how and why greater experience and more reliable measurement techniques are required as particle size shrinks, and the measured phenomena grow weaker. Characterization of Pharmaceutical Nano- and Microsystems deals with a wide variety of topics relevant to chemical and solid-state analysis of drug delivery systems, including drug release, permeation, cell interaction, and safety. It is a complete resource for those interested in the development and manufacture of new medicines, the drug development process, and the translation of those drugs into life-enriching and lifesaving medicines. Characterization of Pharmaceutical Nano- and Microsystems covers all of the following topics: An introduction to the analytical tools applied to determine particle size, morphology, and shape Common chemical approaches to drug system characterization A description of solid-state characterization of drug systems Drug release and permeation studies Toxicity and safety issues The interaction of drug particles with cells Perfect for pharmaceutical chemists and engineers, as well as all other industry professionals and researchers who deal with drug delivery systems on a regular basis, Characterization of Pharmaceutical Nano- and Microsystems also belongs on bookshelves of interested students and faculty who interact with this topic.

Handbook of Lung Targeted Drug Delivery Systems

Handbook of Lung Targeted Drug Delivery Systems
Author: Yashwant Pathak,Nazrul Islam
Publsiher: CRC Press
Total Pages: 690
Release: 2021-10-18
ISBN 10: 1000450805
ISBN 13: 9781000450804
Language: EN, FR, DE, ES & NL

Handbook of Lung Targeted Drug Delivery Systems Book Review:

Handbook of Lung Targeted Drug Delivery Systems: Recent Trends and Clinical Evidences covers every aspect of the drug delivery to lungs, the physiology and pharmacology of the lung, modelling for lung delivery, drug devices focused on lung treatment, regulatory requirements, and recent trends in clinical applications. With the advent of nano sciences and significant development in the nano particulate drug delivery systems there has been a renewed interest in the lung as an absorption surface for various drugs. The emergence of the COVID-19 virus has brought lung and lung delivery systems into focus, this book covers new developments and research used to address the prevention and treatment of respiratory diseases. Written by well-known scientists with years of experience in the field this timely handbook is an excellent reference book for the scientists and industry professionals. Key Features: Focuses particularly on the chemistry, clinical pharmacology, and biological developments in this field of research. Presents comprehensive information on emerging nanotechnology applications in diagnosing and treating pulmonary diseases Explores drug devices focused on lung treatment, regulatory requirements, and recent trends in clinical applications Examines specific formulations targeted to pulmonary systems