The Heparins

The Heparins
Author: David Green
Publsiher: Academic Press
Total Pages: 214
Release: 2020-01-13
ISBN 10: 0128190698
ISBN 13: 9780128190692
Language: EN, FR, DE, ES & NL

The Heparins Book Review:

The Heparins: Properties and Clinical Applications brings the latest information on heparin, one of the world's most widely used drugs. The book describes the fascinating history of the discovery of this biological agent, how it was isolated and characterized, and its use for the treatment of thrombotic disorders. The structures of various heparins are illustrated, with their function as anticoagulants delineated. This comprehensive resource arms researchers and clinicians with a concise and practical source that will assist in biomedical research, medical practice, and in improving patient outcomes. Describes new pharmaceuticals derived from heparin that are devoid of anticoagulant activity, but still retain anti-inflammatory and anti-proliferative properties Discusses the development of non-anticoagulant heparins for the treatment of diseases, including asthma and cancer Presents the history of the discovery of this biological agent, how it was isolated and characterized, and its use for the treatment of thrombotic disorders

Chemistry and Biology of Heparin and Heparan Sulfate

Chemistry and Biology of Heparin and Heparan Sulfate
Author: Hari G. Garg,Robert J. Linhardt,Charles A. Hales
Publsiher: Elsevier
Total Pages: 792
Release: 2011-10-10
ISBN 10: 9780080529059
ISBN 13: 0080529054
Language: EN, FR, DE, ES & NL

Chemistry and Biology of Heparin and Heparan Sulfate Book Review:

The chemistry, biochemistry and pharmacology of heparin and heparan sulfate have been and continue to be a major scientific undertaking - heparin and its derivative remain important drugs in clinical practice. Chemistry and Biology of Heparin and Heparan Sulfate provides readers with an insight into the chemistry, biology and clinical applications of heparin and heparan sulfate and examines their function in various physiological and pathological conditions. Providing a wealth of useful information, no other tome covers the diversity of topics in the field. Students, doctors, chemists, biochemists, and research scientists will find this book an invaluable source for updating their current knowledge of developments in this area. Comprehensively reviews all aspects of heparin and heparan sulfate research Uniquely describes the chemistry, biology and clinical application of heparins and heparan sulfates in one work Provides an invaluable source of knowledge of current developments for chemists, biochemists, medical doctors, researchers, students and practitioners

Cancer Associated Thrombosis

Cancer Associated Thrombosis
Author: Alok A. Khorana,Charles W. Francis
Publsiher: CRC Press
Total Pages: 296
Release: 2007-09-26
ISBN 10: 1420048007
ISBN 13: 9781420048001
Language: EN, FR, DE, ES & NL

Cancer Associated Thrombosis Book Review:

Showcasing the expertise of top-tier specialists who contributed to the newly released guidelines for the care of thrombosis in cancer patients, this exciting guide was written and edited by members of the American Society of Clinical Oncology panel, (ASCO), on the prevention and treatment of cancer-associated thrombosis, among others, and provides

Heparin

Heparin
Author: Deutsche Gesellschaft für Klinische Chemie. Symposium,Irene Witt
Publsiher: de Gruyter
Total Pages: 372
Release: 1983
ISBN 10: 1928374650XXX
ISBN 13: UCAL:B4530693
Language: EN, FR, DE, ES & NL

Heparin Book Review:

Role of the Heparin II Binding Domain in Fibronectin Fibrillogenesis and Signaling

Role of the Heparin II Binding Domain in Fibronectin Fibrillogenesis and Signaling
Author: Amy J. Santas
Publsiher: Unknown
Total Pages: 228
Release: 2000
ISBN 10: 1928374650XXX
ISBN 13: WISC:89077531358
Language: EN, FR, DE, ES & NL

Role of the Heparin II Binding Domain in Fibronectin Fibrillogenesis and Signaling Book Review:

Strategies for Enhancing Enzyme Delivery Using the Heparin protamine based Drug Delivery System

Strategies for Enhancing Enzyme Delivery Using the Heparin protamine based Drug Delivery System
Author: Yongtao Li
Publsiher: Unknown
Total Pages: 135
Release: 2003
ISBN 10: 1928374650XXX
ISBN 13: UOM:39015057703665
Language: EN, FR, DE, ES & NL

Strategies for Enhancing Enzyme Delivery Using the Heparin protamine based Drug Delivery System Book Review:

Heparin Binding Proteins

Heparin Binding Proteins
Author: H. Edward Conrad
Publsiher: Elsevier
Total Pages: 527
Release: 1997-10-02
ISBN 10: 0080533906
ISBN 13: 9780080533902
Language: EN, FR, DE, ES & NL

Heparin Binding Proteins Book Review:

This book describes the complex structures of heparins and heparan sulfates (heparinoids) and how they are generated by their biosynthetic pathways. The book also details the methodologies for studying these structures and their cellular metabolism. Heparin-Binding Proteins introduces the general nature of interactions between heparinoids and proteins, and presents the role for these structures in their interactions with the proteins of the hemostatic mechanisms, fibroblasts growth factors, superoxide dismutase, and lipoproteins. Covers cellular metabolism of heparinoid proteoglycans Written by a distinguished expert in the field of carbohydrate biochemistry Describes the roles of heparan sulfate proteoglycans in Blood coagulation and fibrinolysis Lipoprotein metabolism Superoxide dismutase activity Fibroblast growth factor responses of cells

Heparin Structure Cellular Functions and Clinical Applications

Heparin  Structure  Cellular Functions  and Clinical Applications
Author: Norman Mcduffie
Publsiher: Elsevier
Total Pages: 410
Release: 2012-12-02
ISBN 10: 0323151620
ISBN 13: 9780323151627
Language: EN, FR, DE, ES & NL

Heparin Structure Cellular Functions and Clinical Applications Book Review:

Heparin: Structure, Cellular Functions, and Clinical Applications compiles lectures presented at the International Symposium on Heparin held at Saskatoon on July 6-8, 1977. Heparin has been the leader in antithrombotic therapy ever since its introduction several years ago. This substance initiated a field of therapeutics and made possible dramatic advances in cardiac surgery, vascular surgery, acute and chronic hemodialysis, and a variety of other medical and surgical procedures. This book discusses several concepts pertaining to the heparin molecule, its pharmacology, physiology, and clinical application. Other topics covered include the use of heparin in preventing thrombosis; use of pharmacodynamic studies for establishing dosage; identification of differences in heparins among various mammalian species; and methods for the determination of heparin. The demonstration of the platelet aggregating effect of commercial heparin preparations; heparin's reaction with toluidine blue; identification of iduronic acid as a major component of heparin; and identification of circulating heparin in canine anaphylaxis are discussed as well. This compilation is a good reference for students and individuals conducting research on heparin and its physiological role.

Heparin A Century of Progress

Heparin   A Century of Progress
Author: Rebecca Lever,Barbara Mulloy,Clive P. Page
Publsiher: Springer Science & Business Media
Total Pages: 462
Release: 2012-05-08
ISBN 10: 3642230563
ISBN 13: 9783642230561
Language: EN, FR, DE, ES & NL

Heparin A Century of Progress Book Review:

Heparins remain amongst the most commonly used drugs in clinical practice. Almost 100 years have passed since the initial discovery of this complex substance and, during this time, understanding of the nature and uses of heparin and related molecules has grown dramatically. The aim of this volume is to summarise the developments that have led to the current status of both heparins as drugs and the field of heparin research, with a focus on the particularly rapid progress that has been made over the past three decades. Individual sections are dedicated to the nature of heparin as a biological molecule, the current approaches and techniques that are used to ensure the safety and reliability of heparin as a medicine, the clinical pharmacology of heparin as an anticoagulant drug, effects and potential applications of heparin aside of those involving haemostasis and, finally, the nature and potential uses of heparin-like materials from both natural and synthetic sources.

Biology and Pathology of Platelet vessel Wall Interactions

Biology and Pathology of Platelet vessel Wall Interactions
Author: Rhône-Poulenc-Santé (Firm),Institut national de la santé et de la recherche médicale (France)
Publsiher: Unknown
Total Pages: 413
Release: 1986
ISBN 10: 1928374650XXX
ISBN 13: UOM:39015012535343
Language: EN, FR, DE, ES & NL

Biology and Pathology of Platelet vessel Wall Interactions Book Review:

A Proton Magnetic Resonance Spectral Study of Heparin L iduronic Acid Residues in Commercial Heparins

A Proton Magnetic Resonance Spectral Study of Heparin  L iduronic Acid Residues in Commercial Heparins
Author: A. S. Perlin,M. Mazurek,L. B. Jaques,L. W. Kavanagh,NATIONAL RESEARCH COUNCIL OF CANADA SASKATOON (Sask.) PRAIRIE REGIONAL LAB.
Publsiher: Unknown
Total Pages: 11
Release: 1968
ISBN 10: 1928374650XXX
ISBN 13: OCLC:227501191
Language: EN, FR, DE, ES & NL

A Proton Magnetic Resonance Spectral Study of Heparin L iduronic Acid Residues in Commercial Heparins Book Review:

The p.m.r. spectra of commercial heparin samples from a variety of sources indicate that there are at least two types of heparin. These types are differentiated by small, but distinct, variations in the relative intensities of their proton signals and, most noticeably, by the presence of acetyl groups in samples of one of the types. The spectral data also indicate that approximately equimolar proportions of three kinds of constituent sugar residues are present in all of the heparin samples. Deaminative degradation of a heparin, followed by exhaustive reduction of the carboxyl groups, acetolysis, and deacetylation, yielded L-idose as a major product. It is tentatively concluded that L-idosyluronic acid residues constitute about one-third of the constituent sugars of the commercial heparins, and that the aminodeoxy-D-hexosyl and D-glucosyluronic residues (already recognized as constituents) each constitute one-third of the polymeric material. (Author).

Practical Transfusion Medicine

Practical Transfusion Medicine
Author: Michael F. Murphy,Derwood H. Pamphilon
Publsiher: John Wiley & Sons
Total Pages: 576
Release: 2013-07-03
ISBN 10: 1118702999
ISBN 13: 9781118702994
Language: EN, FR, DE, ES & NL

Practical Transfusion Medicine Book Review:

This new edition of the comprehensive guide to transfusion medicine is now fully revised and updated. The Third Edition includes two new sections, one on alternatives to blood transfusion, and one on cellular and tissues therapy and organ transplantation. It focuses on clinical aspects but also covers background science and organizational issues. This timely volume highlights controversial issues and provides advice for everyday clinical questions in transfusion medicine. Practical Transfusion Medicine, Third Edition, is an essential manual for all those working in modern transfusion medicine.

Heparin Induced Thrombocytopenia

Heparin Induced Thrombocytopenia
Author: Theodore Warkentin,Andreas Greinacher
Publsiher: CRC Press
Total Pages: 627
Release: 2003-12-05
ISBN 10: 0824758846
ISBN 13: 9780824758844
Language: EN, FR, DE, ES & NL

Heparin Induced Thrombocytopenia Book Review:

Taking stock of advances in clinical recognition, laboratory testing, and pharmacologic therapy as well as basic aspects of pathogenesis, the Third Edition of Heparin-Induced Thrombocytopenia reinforces its standing as the leading guide to accurate diagnosis and effective management of this complex condition. Featuring added chapters on bivalirudin

Biological Response Modifiers in Treatment of Cancer

Biological Response Modifiers in Treatment of Cancer
Author: Kenth Johansson,Matti Laato
Publsiher: Unknown
Total Pages: 64
Release: 1988
ISBN 10: 1928374650XXX
ISBN 13: OSU:32436000690279
Language: EN, FR, DE, ES & NL

Biological Response Modifiers in Treatment of Cancer Book Review:

Low molecular weight Heparins in Prophylaxis and Therapy of Thromboembolic Diseases

Low molecular weight Heparins in Prophylaxis and Therapy of Thromboembolic Diseases
Author: H. Bounameaux
Publsiher: Marcel Dekker Incorporated
Total Pages: 323
Release: 1994
ISBN 10: 1928374650XXX
ISBN 13: UOM:39015037337113
Language: EN, FR, DE, ES & NL

Low molecular weight Heparins in Prophylaxis and Therapy of Thromboembolic Diseases Book Review:

Provides information for both basic scientists and specialist clinicians on the new class of heparin fractions developed in France in the 1980s and now gradually replacing the old unfractionated heparin for the treatment and prevention of venous thromboembolism. Among the topics are the pharmacology, the mode of action in plasma, interaction with platelets, and prevention following various kinds of surgery. Annotation c. by Book News, Inc., Portland, Or.

Low Molecular Weight Heparins

Low Molecular Weight Heparins
Author: J. Monasterio,M. M. Samama
Publsiher: S Karger Ag
Total Pages: 65
Release: 1996
ISBN 10: 1928374650XXX
ISBN 13: CORNELL:31924077702847
Language: EN, FR, DE, ES & NL

Low Molecular Weight Heparins Book Review:

Low-molecular-weight (LMW) heparins are increasingly used in the prevention and treatment of thromboembolic disease because, compared to unfractionated heparins, they show a higher benefit/risk ratio and better clinical convenience. This special issue reports the proceedings of a symposium which reviewed all the available data on the properties of these agents and their therapeutic applications. Several contributions present studies on the use of LMW heparins in the prophylaxis of venous thromboembolism after surgery and in nonsurgical situations, as well as in the treatment of established venous thrombosis. Arterial thrombosis as another potential indication for LMW heparins is discussed. Authoritative and up-to-date, this publication is essential reading for anyone dealing with thromboembolic disease from a pharmacological or a clinical point of view.

Anticoagulation Drugs

Anticoagulation Drugs
Author: Mina Kelleni
Publsiher: BoD – Books on Demand
Total Pages: 104
Release: 2020-03-18
ISBN 10: 1789850754
ISBN 13: 9781789850758
Language: EN, FR, DE, ES & NL

Anticoagulation Drugs Book Review:

In this book, you'll find the latest updates about the current use of anticoagulants in medical practice. This includes clinical pharmacotherapy, laboratory monitoring, and antidotes. You'll also find a special focus on heparin-induced thrombocytopenia, including various mechanisms and presentations. Finally, you'll find important details that will help you to understand what patients receiving anticoagulants know about these drugs and how to improve their quality of life.

Heparin A Century of Progress

Heparin   A Century of Progress
Author: Rebecca Lever,Barbara Mulloy,Clive P. Page
Publsiher: Springer
Total Pages: 462
Release: 2014-06-11
ISBN 10: 9783642434587
ISBN 13: 3642434584
Language: EN, FR, DE, ES & NL

Heparin A Century of Progress Book Review:

Heparins remain amongst the most commonly used drugs in clinical practice. Almost 100 years have passed since the initial discovery of this complex substance and, during this time, understanding of the nature and uses of heparin and related molecules has grown dramatically. The aim of this volume is to summarise the developments that have led to the current status of both heparins as drugs and the field of heparin research, with a focus on the particularly rapid progress that has been made over the past three decades. Individual sections are dedicated to the nature of heparin as a biological molecule, the current approaches and techniques that are used to ensure the safety and reliability of heparin as a medicine, the clinical pharmacology of heparin as an anticoagulant drug, effects and potential applications of heparin aside of those involving haemostasis and, finally, the nature and potential uses of heparin-like materials from both natural and synthetic sources.

Clinical Pharmacokinetics

Clinical Pharmacokinetics
Author: John E. Murphy
Publsiher: Unknown
Total Pages: 500
Release: 2016
ISBN 10: 9781585285365
ISBN 13: 1585285366
Language: EN, FR, DE, ES & NL

Clinical Pharmacokinetics Book Review:

Handbook of nutrition and diet in leukemia and blood disease therapy

Handbook of nutrition and diet in leukemia and blood disease therapy
Author: Ronald Ross Watson,Daruka Mahadevan
Publsiher: Wageningen Academic Publishers
Total Pages: 378
Release: 2016-02-09
ISBN 10: 9086868223
ISBN 13: 9789086868223
Language: EN, FR, DE, ES & NL

Handbook of nutrition and diet in leukemia and blood disease therapy Book Review:

This handbook provides an overview of the latest science of the influence of nutrition on blood cells and blood diseases. Blood diseases include a broad range of nutritional deficiencies, leukemias and genetic mutations, associated with an increased risk of infections. Reduced red blood cell production can lead to nutritional diseases and anemias, requiring iron supplementation. Patients with anemia feel sick, fatigued and have nausea affecting food intake, worsening their condition. Changes in serum and blood cells affect coagulation, as well as the immune cells’ production of cytokines and immunoglobulin. The blood cells interactions affect all major organ systems. Nutrition and food plays a key role in the health of blood cells and their functions. Vitamins and minerals, such as vitamin E, C and iron, affect the production of blood cells and their proteins, including hemoglobin. In addition, other nutrients, like glutamine, L-carnitine and the amino-acid taurine, play a crucial role in the production of blood cells and blood/related diseases. This book discusses nutritional therapies concerning stem cell transplantation, iron deficiency, cardiovacular diseases, sickle cell anemia and sepsis patients, among others. Nutritional therapy and management in leukemia is given a major focus. The key goal of this handbook is to review some of the nutritional approaches for efficacy in treatment of blood diseases, reduction of their clinical complications and the improvement of the quality of life of these patients.