The Cytokines of the Immune System

The Cytokines of the Immune System
Author: Zlatko Dembic
Publsiher: Academic Press
Total Pages: 320
Release: 2015-05-23
ISBN 10: 0124200109
ISBN 13: 9780124200104
Language: EN, FR, DE, ES & NL

The Cytokines of the Immune System Book Review:

The Cytokines of the Immune System catalogs cytokines and links them to physiology and pathology, providing a welcome and hugely timely tool for scientists in all related fields. In cataloguing cytokines, it lists their potential for therapeutic use, links them to disease treatments needing further research and development, and shows their utility for learning about the immune system. This book offers a new approach in the study of cytokines by combining detailed guidebook-style cytokine description, disease linking, and presentation of immunologic roles. Supplies new ideas for basic and clinical research Provides cytokine descriptions in a guidebook-style, cataloging the origins, structures, functions, receptors, disease-linkage, and therapeutic potentials Offers a textbook-style view on the immune system with the immunologic role of each cytokine

The Cytokines of the Immune System

The Cytokines of the Immune System
Author: Zlatko Dembic
Publsiher: Academic Press
Total Pages: 320
Release: 2015-05-01
ISBN 10: 9780124199989
ISBN 13: 0124199984
Language: EN, FR, DE, ES & NL

The Cytokines of the Immune System Book Review:

The Cytokines of the Immune System catalogs cytokines and links them to physiology and pathology, providing a welcome and hugely timely tool for scientists in all related fields. In cataloguing cytokines, it lists their potential for therapeutic use, links them to disease treatments needing further research and development, and shows their utility for learning about the immune system. This book offers a new approach in the study of cytokines by combining detailed guidebook-style cytokine description, disease linking, and presentation of immunologic roles. Supplies new ideas for basic and clinical research Provides cytokine descriptions in a guidebook-style, cataloging the origins, structures, functions, receptors, disease-linkage, and therapeutic potentials Offers a textbook-style view on the immune system with the immunologic role of each cytokine

Cytokine Frontiers

Cytokine Frontiers
Author: Takayuki Yoshimoto,Tomohiro Yoshimoto
Publsiher: Springer Science & Business Media
Total Pages: 396
Release: 2013-10-28
ISBN 10: 4431544429
ISBN 13: 9784431544425
Language: EN, FR, DE, ES & NL

Cytokine Frontiers Book Review:

This book guides the reader through the latest research on the cytokine network, covering signaling pathways, control of the immune response, and potential therapeutics. Different cytokines stimulate diverse responses in various phases of inflammation and immunity, including the innate immune response, the generation of effector T cells, and the development of antibodies by the humoral immune system. It is now clear that the pathophysiology of many infectious, autoimmune, allergic, and malignant diseases can be largely explained by which cytokines are induced and subsequently regulate the cellular responses. In clinical medicine, cytokines are involved in a wide spectrum of diseases. This book describes in three parts the properties and roles of 15 key cytokines under physiological and pathological conditions. Part I presents nine cytokines associated with inflammatory disorders, pro-inflammatory cytokines, and the recently identified new helper T (Th) subset: Th17 cells. Part II gives details of three cytokines associated with allergic disorders, including Th2 responses and recently identified types of innate cells. Part III describes three cytokines that are associated with immunological tolerance and anti-inflammation, including regulatory T (Treg) cells, IL-10-producing Treg (Tr1) cells, and inducible IL-35-producing Treg (iTr35) cells. Cytokines are considered to be important as therapeutic targets for specific agonists or antagonists in numerous immune and inflammatory diseases. The ultimate goal of this book is to facilitate the development of therapeutic treatments for such diseases which has been limited by an insufficient understanding of the biology of cytokines and the complicated network that they create.

Cytokines

Cytokines
Author: Robert E. Faith,Anthony J. Murgo,Robert A. Good,Nicholas P. Plotnikoff
Publsiher: CRC Press
Total Pages: 405
Release: 2006-10-10
ISBN 10: 1420003801
ISBN 13: 9781420003802
Language: EN, FR, DE, ES & NL

Cytokines Book Review:

Cytokine involvement in the immune system's response to stress is now very well documented. Cytokine activity has been implicated in a variety of mental and physical diseases, and has been shown to have a significant role in fueling the vicious circle of depression and illness. The first edition of Cytokines: Stress and Immunity pointed out

Janeway s Immunobiology

Janeway s Immunobiology
Author: Murphy, Kenneth M.,Weaver, Casey
Publsiher: W.W. Norton & Company
Total Pages: 904
Release: 2016-03-22
ISBN 10: 0815345518
ISBN 13: 9780815345510
Language: EN, FR, DE, ES & NL

Janeway s Immunobiology Book Review:

Explore the premier text for immunology at the advanced undergraduate, graduate, and medical school levels. Beginning students appreciate the bookÕs clear writing and informative illustrations, while advanced students and working immunologists value its comprehensive scope and depth. This edition is thoroughly revised and up to date with significant developments in the field, especially on the topic of innate immunity.

Military Strategies for Sustainment of Nutrition and Immune Function in the Field

Military Strategies for Sustainment of Nutrition and Immune Function in the Field
Author: Institute of Medicine,Committee on Military Nutrition Research
Publsiher: National Academies Press
Total Pages: 722
Release: 1999-05-13
ISBN 10: 9780309173186
ISBN 13: 0309173183
Language: EN, FR, DE, ES & NL

Military Strategies for Sustainment of Nutrition and Immune Function in the Field Book Review:

Every aspect of immune function and host defense is dependent upon a proper supply and balance of nutrients. Severe malnutrition can cause significant alteration in immune response, but even subclinical deficits may be associated with an impaired immune response, and an increased risk of infection. Infectious diseases have accounted for more off-duty days during major wars than combat wounds or nonbattle injuries. Combined stressors may reduce the normal ability of soldiers to resist pathogens, increase their susceptibility to biological warfare agents, and reduce the effectiveness of vaccines intended to protect them. There is also a concern with the inappropriate use of dietary supplements. This book, one of a series, examines the impact of various types of stressors and the role of specific dietary nutrients in maintaining immune function of military personnel in the field. It reviews the impact of compromised nutrition status on immune function; the interaction of health, exercise, and stress (both physical and psychological) in immune function; and the role of nutritional supplements and newer biotechnology methods reported to enhance immune function. The first part of the book contains the committee's workshop summary and evaluation of ongoing research by Army scientists on immune status in special forces troops, responses to the Army's questions, conclusions, and recommendations. The rest of the book contains papers contributed by workshop speakers, grouped under such broad topics as an introduction to what is known about immune function, the assessment of immune function, the effect of nutrition, and the relation between the many and varied stresses encountered by military personnel and their effect on health.

Cytokine Storm Syndrome

Cytokine Storm Syndrome
Author: Randy Q. Cron,Edward M. Behrens
Publsiher: Springer Nature
Total Pages: 617
Release: 2019-09-09
ISBN 10: 303022094X
ISBN 13: 9783030220945
Language: EN, FR, DE, ES & NL

Cytokine Storm Syndrome Book Review:

Cytokine Storm Syndromes, including HLH and MAS, are frequently fatal disorders, particularly if not recognized early and treated during presentation. The genetics of Cytokine Storm Syndromes are being defined with many of the risk alleles giving rise to mutations in the perforin-mediated cytolytic pathway used by CD8 cytotoxic T cells and natural killer cells. These are being studied using murine models. Up to 10% of the general population may carry risk alleles for developing Cytokine Storm Syndromes, and Cytokine Storm Syndromes are being increasingly recognized around the world in pediatric and adult hospitals. A variety of infectious, rheumatic, and oncologic triggers are commonly associated with Cytokine Storm Syndromes, but understanding this disorder is critical for all researchers and physicians to ensure timely and appropriate therapy. This textbook, the first of its kind, addresses all aspects of the disorder – from genetics, pathophysiology, and ongoing research, to clinical presentations, risk factors, and treatment.

Molecular Biology of the Cell

Molecular Biology of the Cell
Author: Bruce Alberts
Publsiher: Unknown
Total Pages: 329
Release: 2004
ISBN 10: 9780815332183
ISBN 13: 0815332181
Language: EN, FR, DE, ES & NL

Molecular Biology of the Cell Book Review:

Adverse Effects of Vaccines

Adverse Effects of Vaccines
Author: Institute of Medicine,Board on Population Health and Public Health Practice,Committee to Review Adverse Effects of Vaccines
Publsiher: National Academies Press
Total Pages: 894
Release: 2012-04-26
ISBN 10: 0309214351
ISBN 13: 9780309214353
Language: EN, FR, DE, ES & NL

Adverse Effects of Vaccines Book Review:

In 1900, for every 1,000 babies born in the United States, 100 would die before their first birthday, often due to infectious diseases. Today, vaccines exist for many viral and bacterial diseases. The National Childhood Vaccine Injury Act, passed in 1986, was intended to bolster vaccine research and development through the federal coordination of vaccine initiatives and to provide relief to vaccine manufacturers facing financial burdens. The legislation also intended to address concerns about the safety of vaccines by instituting a compensation program, setting up a passive surveillance system for vaccine adverse events, and by providing information to consumers. A key component of the legislation required the U.S. Department of Health and Human Services to collaborate with the Institute of Medicine to assess concerns about the safety of vaccines and potential adverse events, especially in children. Adverse Effects of Vaccines reviews the epidemiological, clinical, and biological evidence regarding adverse health events associated with specific vaccines covered by the National Vaccine Injury Compensation Program (VICP), including the varicella zoster vaccine, influenza vaccines, the hepatitis B vaccine, and the human papillomavirus vaccine, among others. For each possible adverse event, the report reviews peer-reviewed primary studies, summarizes their findings, and evaluates the epidemiological, clinical, and biological evidence. It finds that while no vaccine is 100 percent safe, very few adverse events are shown to be caused by vaccines. In addition, the evidence shows that vaccines do not cause several conditions. For example, the MMR vaccine is not associated with autism or childhood diabetes. Also, the DTaP vaccine is not associated with diabetes and the influenza vaccine given as a shot does not exacerbate asthma. Adverse Effects of Vaccines will be of special interest to the National Vaccine Program Office, the VICP, the Centers for Disease Control and Prevention, vaccine safety researchers and manufacturers, parents, caregivers, and health professionals in the private and public sectors.

Cytokines and Pain

Cytokines and Pain
Author: L.R. Watkins,S.F. Maier
Publsiher: Springer
Total Pages: 232
Release: 2013-03-08
ISBN 10: 3034887493
ISBN 13: 9783034887496
Language: EN, FR, DE, ES & NL

Cytokines and Pain Book Review:

Within the past few years, it has become recognized that the immune system communicates to the brain. Substances released from activated immune cells (cytokines) stimulate peripheral nerves, thereby signaling the brain and spinal cord that infection/inflammation has occurred. Additionally, peripheral infection/inflammation leads to de novo synthesis and release of cytokines within the brain and spinal cord. Thus, cytokines effect neural activation both peripherally and centrally. Through this communication pathway, cytokines such as interleukin-1, interleukin-6 and tumor necrosis factor markedly alter brain function, physiology and behavior. One important but underrecognized aspect of this communication is the dramatic impact that immune activation has on pain modulation. The purpose of this book is to examine, for the first time, immune-to-brain communication from the viewpoint of its effect on pain processing. It is aimed both at the basic scientist and health care providers, in order to clarify the major role that substances released by immune cells play in pain modulation. This book contains chapters contributed by all of the major laboratories focused on understanding how cytokines modulate pain. These chapters provide a unique vantage point from which to examine this question, as the summarized work ranges from evolutionary approaches across diverse species, to the basics of the immune response, to the effect of cytokines on peripheral and central nervous system sites, to therapeutic potential in humans.

Stress and Immunity

Stress and Immunity
Author: Nicholas P. Plotnikoff,Anthony J. Murgo,Robert E. Faith
Publsiher: CRC Press
Total Pages: 576
Release: 1991-10-23
ISBN 10: 9780849388453
ISBN 13: 0849388457
Language: EN, FR, DE, ES & NL

Stress and Immunity Book Review:

Stress and Immunity introduces and updates the status of research on stress and immunity. Clinical aspects of stress and immunity are presented in the first 17 chapters and include discussions regarding the influence of depression disorders on immune functions and stress interrelationships with cancer, AIDS, Chronic Fatigue Syndrome, and Herpes Simplex infections. There is also a review of physical exercise and immunity. The second half of the book is devoted to discussions regarding basic research being conducted in the field of stress and immunity. This includes discussions on the interrelationships of the central nervous system and the immune system and research on stress hormones (e.g., enkephalins, endorphins) as they interrelate with the immune system. In addition, animal models for the study of stress and immunity are discussed. Psychiatrists, neurologists, psychologists, clinical psychologists, internists, immunologists, and researchers in psychosomatic disorders should consider this an essential reference volume.

Cytokines and the Brain

Cytokines and the Brain
Author: Anonim
Publsiher: Elsevier
Total Pages: 608
Release: 2008-06-18
ISBN 10: 9780080559353
ISBN 13: 0080559352
Language: EN, FR, DE, ES & NL

Cytokines and the Brain Book Review:

This book opens a new page of neuro-immunobiology providing substantive experimental and clinical data to support current understanding in the field, and potential applications of this knowledge in the treatment of disease. The volume is a collection of complex, new data drawn from multiple areas of investigation in the field. The contents summarize current understanding on the presence and function of CNS cytokines and their receptors in a variety of CNS cells during health and disease. The chapters are a collection of complex, new data demonstrating the presence and synthesis of cytokines in brain cells, as well as their receptors on cell membranes in health and disease. The strength of the volume are the descriptions of the authors own investigations, together with those of others in the field pertaining to a large number of cytokines in brain function, as well as mechanisms involved in the development of CNS disorders, including multiple sclerosis and Alzheimer’s disease. Also included are novel approaches to the treatment of CNS disorders based on new experimental data. The contributors to this volume are internationally known scientists and clinical researchers in their respective fields of investigation and treatment. *Opens a new page of neuro-immunobiology and provides substantive evidence for the promise of this field in the treatment of disease *Summarizes current understanding on the presence and function of central nervous system (CNS) cytokines and their receptors in a variety of CNS cells during health and disease *Includes novel approaches to the treatment of CNS disorders based on new experimental data *Offers new insight into triggers for the development of autoimmune diseases in the brain and the possibilities for treatment

Principles of Cancer Biotherapy

Principles of Cancer Biotherapy
Author: Robert K. Oldham,Robert O. Dillman
Publsiher: Springer Science & Business Media
Total Pages: 742
Release: 2009-08-29
ISBN 10: 9789048122899
ISBN 13: 9048122899
Language: EN, FR, DE, ES & NL

Principles of Cancer Biotherapy Book Review:

At the time of the first edition of Principles of Cancer Biotherapy in 1987, this book represented the first comprehensive textbook on biological therapy. In 1991, when the second edition was published, there was still some doubt on the part of many oncologists and cancer researchers as to the therapeutic value of these new approaches. By 2003 and the fourth edition, it was generally agreed that biopharmaceuticals were producing major opportunities for new cancer therapies. Cancer biotherapy has now truly matured into the fourth modality of cancer treatment. This fifth revised edition describes the tremendous progress that has been made in recent years using biologicals in cancer treatment. This book summarizes an evolving science and a rapidly changing medical practice in biotherapy. In this new millennium, it is now possible to envision a much more diversified system of cancer research and treatment that will afford greater opportunities for a patient’s personalized cancer treatment. This was first envisioned in the 1987 initial edition of this textbook and is now a “new” and popular approach to cancer treatment. Some forms of cancer biotherapy use the strategy of tumor stabilization and control through continued biological therapy, akin to the use of insulin in the treatment of diabetes. This textbook illustrates new methods of thinking and new strategies for control of cancer. It is always difficult to move from past dogma to future opportunity, but this fifth edition of Principles of Cancer Biotherapy illustrates why it is so important to the patients for researchers and clinicians to explore and quickly apply these new opportunities in cancer biotherapy.

Recent Developments in Myelodysplastic Syndromes

Recent Developments in Myelodysplastic Syndromes
Author: Ota Fuchs
Publsiher: BoD – Books on Demand
Total Pages: 120
Release: 2019-02-20
ISBN 10: 1789854776
ISBN 13: 9781789854770
Language: EN, FR, DE, ES & NL

Recent Developments in Myelodysplastic Syndromes Book Review:

This book deals with the rapid progress in the area of myelodysplastic syndromes (MDS). MDS are a group of age-associated heterogeneous malignant bone marrow stem cell disorders. MDS are characterized by ineffective hematopoiesis, which leads to refractory cytopenias and to clonal instability. Patients with MDS have myeloid dysplasia, intramedullary apoptosis and an increased risk of transformation to acute myeloid leukemia (AML). The use of next generation sequencing has allowed for the identification of molecular mutations in several genes in about 90% of MDS patients. Several mutations will likely be incorporated into future prognostic scoring systems for MDS. About 50% of MDS cases are characterized by the presence of cytogenetic abnormalities. The correct morphological and cytogenetic analysis interpretation plays an important role in diagnosis and prognosis of these disorders. Cell death and an inflammatory gene signature are associated with MDS. Better understanding of the genetic and molecular mechanisms of MDS pathogenesis provides an opportunity for new treatment strategies to be developed. Promising novel therapies targeting pathophysiological mechanisms of MDS are being studied but the drugs currently used in MDS therapy remain limited. The only curative therapy for MDS is allogeneic hematopoietic stem cell transplantation. Recent advances in strategies to minimize transplant-related toxicity make this treatment possible for more MDS patients who are sufficiently fit.

Cytokines

Cytokines
Author: Victor R. Preedy,Ross Hunter
Publsiher: CRC Press
Total Pages: 450
Release: 2011-06-24
ISBN 10: 9781578086900
ISBN 13: 1578086906
Language: EN, FR, DE, ES & NL

Cytokines Book Review:

Cytokines are a group of peptides secreted by cells of the immune system such as macrophages, lymphocytes, and T cells. They can be divided into functional families and have-wide ranging impacts that affect cells and molecular pathways to the whole individual. Written by distinguished scholars and experts, this book is a holistic reference to enable scientists and doctors to understand cytokines in specific or broad detail. The book is divided into sections that cover general and cellular aspects, lifestyle factors, immunology and infections, cancer, cardiovascular and metabolic disease, and organs and tissue systems.

Cytokines Stress and Depression

Cytokines  Stress  and Depression
Author: Robert Dantzer,Emmanuelle E. Wollmann,Raz Yirmiya
Publsiher: Springer Science & Business Media
Total Pages: 338
Release: 2007-11-23
ISBN 10: 058537970X
ISBN 13: 9780585379708
Language: EN, FR, DE, ES & NL

Cytokines Stress and Depression Book Review:

Cytokines had been characterized in the early eighties as communication mole cules between immune cells, and between immunocytes and other peripheral cells, such as fibroblasts and endothelial cells. They play a key role in the regulation of the immune response and the coordination of the host response to infection. Based on these biological properties, nobody would have predicted that one decade later cytokines would burst upon neurosciences and permeate into several avenues of current research. In neurology, the connection between cytokines and inflammation, and the demonstration of a pivotal role of some of these molecules in cell death by apoptosis, prompted the investigation of their involvement in several neurological diseases involving an inflammatory component, including multiple sclerosis, brain trauma, stroke, and Alzheimer's disease. This movement started in the late eighties, and the corresponding field of research, known as neuroimmunology, is presently booming. In psychiatry, however, the relationship between cytokines and mental disorders was much less evident and took longer to materialize. The first indication that cytokines might be involved in psychopathology came from cancerology and internal medicine.

Cytokines and Their Therapeutic Potential

Cytokines and Their Therapeutic Potential
Author: Manzoor Ahmad Mir
Publsiher: Unknown
Total Pages: 168
Release: 2020-03-05
ISBN 10: 9781536170177
ISBN 13: 1536170178
Language: EN, FR, DE, ES & NL

Cytokines and Their Therapeutic Potential Book Review:

The book "Cytokines and Their Therapeutic Potential" comprises of five chapters and describes the origin, production and scope of cytokines, which are the most important molecules of immune system around which the field of functional immunology revolves. This book describes how the immune system responds to injuries and insults by foreign antigens (bacteria, viruses etc.) and produces cytokines, which then, through various immune response mechanisms, protect the body against pathogenic invasions, how these glycoproteins are involved in the differentiation and maturation of immune cells, how lymph nodes are involved in concentrating the different forms of cytokines, how immunogenicity of a cytokine is affected and how a cytokine is related to the immune response. Various types of cytokines and the organization and expression of cytokine receptors are described separately. The properties, mechanistic function and therapeutic cytokines are also discussed in separate chapters. The characteristics, production and important roles played by different cytokines in research, diagnostics and therapeutics is described separately. Lastly the role of cytokines and chemokine's in infectious diseases and their importance in the detection of various kinds of diseases like cancer, HIV-AIDS, tuberculosis, malaria etc. are discussed in detail separately. The book contains a reasonable number of diagrams, flowcharts and tables. Besides this, various interesting and self-explanatory illustrations are incorporated to make the book useful to the students for whom it is written. The question bank, which includes long answer type, short answer type and multiple choice questions with their answers at the very end of each chapter, is developed to get a full grasp of the topic.

Tropical Diseases

Tropical Diseases
Author: Sangkot Marzuki,Jan Verhoef,Harm Snippe
Publsiher: Springer Science & Business Media
Total Pages: 386
Release: 2003-07-31
ISBN 10: 9780306477997
ISBN 13: 0306477998
Language: EN, FR, DE, ES & NL

Tropical Diseases Book Review:

For example, the book discusses traditional tropical medicine topics of infectious diseases and nutritional deficiencies. These diseases are common in the tropics, although some are associated more with poverty than with tropical living conditions. It also deals with genetic diseases and genomic issues that are truly associated with living in the tropics, e.g. the thalassemias. The book begins with several papers describing the vast human genetic diversity of Southeast Asia and its relationship to several genetic disorders. These papers illustrate the future direction of genomic activities in relation to disease susceptibility and resistance. The next sections deal with malaria and four specific viral and bacterial diseases of the tropics: hepatitis B and C, tuberculosis, and leprosy. These are then followed by a section on general bacterial infection. Two papers on nutrition complete the volume.

Cytokine Effector Functions in Tissues

Cytokine Effector Functions in Tissues
Author: Maria Foti,Massimo Locati
Publsiher: Academic Press
Total Pages: 304
Release: 2017-07-17
ISBN 10: 0128042192
ISBN 13: 9780128042199
Language: EN, FR, DE, ES & NL

Cytokine Effector Functions in Tissues Book Review:

Cytokine Effector Functions in Tissues discusses the cytokines networks in the context of the specific-tissue environment. It is an up-to-date collection of articles that addresses the specific issue of how the cytokines are able to condition tissue specific homeostasis. The book helps the reader understand how cytokines network inside the tissues and highlights whether tissue-protection or exacerbation will be finally controlled. It describes the cytokines detected and regulated in different tissues, such as the brain, lungs, spleen, liver, pancreas and intestine, also addressing the issue of timing in specific cell types. Categorizes the cytokines based primarily on tissue and target cells Emphasizes different roles and outcomes observed during innate and adaptive response Represents a rapid guide to cytokines in health and disease in tissue and organ context Presents a different view on how known mediators may work if analyzed in a different perspective, determining the final outcome on tissue-specific target cells

Textbook of Immunology

Textbook of Immunology
Author: Constantin A. Bona,Francisco A. Bonilla
Publsiher: CRC Press
Total Pages: 300
Release: 2019-11-11
ISBN 10: 1000717402
ISBN 13: 9781000717402
Language: EN, FR, DE, ES & NL

Textbook of Immunology Book Review:

Building on the strengths of the first edition, the newly titled and expanded second edition remains a concise introduction to the fundamentals of immunology, with an expert synthesis of basic and clinical information., Augmented by color illustrations, and with increased emphasis on the molecular and genetic underpinnings of cellular phenomena, Textbook of Immunology covers the physiology of the immune system, disease entities related to immune system dysfunction, and the underlying pathophysiologic mechanisms of dysfunction. In response to advancing knowledge that influences the approach to presenting basic immunology, new chapters have been added on cytokines; host defense (non-specific immunity and specific immune responses); the aging immune system; and the pathophysiology, diagnosis, prevention, and therapy of AIDS., This book keeps pace with the explosion of information and data in immunology, and adeptly refines, organizes, and presents this body of knowledge to serve as a succinct introduction to modern immunologic concepts for medical students, and as an update and refresher in the basics for researchers and clinicians.