Targeting Chronic Inflammatory Lung Diseases Using Advanced Drug Delivery Systems

Targeting Chronic Inflammatory Lung Diseases Using Advanced Drug Delivery Systems
Author: Kamal Dua,Philip M. Hansbro,Ridhima Wadhwa,Mehra Haghi,Lisa G. Pont,Kylie A. Williams
Publsiher: Academic Press
Total Pages: 616
Release: 2020-08-04
ISBN 10: 0128208880
ISBN 13: 9780128208885
Language: EN, FR, DE, ES & NL

Targeting Chronic Inflammatory Lung Diseases Using Advanced Drug Delivery Systems Book Review:

Targeting Chronic Inflammatory Lung Diseases Using Advanced Drug Delivery Systems explores the development of novel therapeutics and diagnostics to improve pulmonary disease management, looking down to the nanoscale level for an efficient system of targeting and managing respiratory disease. The book examines numerous nanoparticle-based drug systems such as nanocrystals, dendrimers, polymeric micelles, protein-based, carbon nanotube, and liposomes that can offer advantages over traditional drug delivery systems. Starting with a brief introduction on different types of nanoparticles in respiratory disease conditions, the book then focuses on current trends in disease pathology that use different in vitro and in vivo models. The comprehensive resource is designed for those new to the field and to specialized scientists and researchers involved in pulmonary research and drug development. Explores recent perspectives and challenges regarding the management and diagnosis of chronic respiratory diseases Provides insights into how advanced drug delivery systems can be effectively formulated and delivered for the management of various pulmonary diseases Includes the most recent information on diagnostic methods and treatment strategies using controlled drug delivery systems (including nanotechnology)

Targeting Cellular Signalling Pathways in Lung Diseases

Targeting Cellular Signalling Pathways in Lung Diseases
Author: Kamal Dua,Raimar Löbenberg,Angela Cristina Malheiros Luzo,Shakti Shukla,Saurabh Satija
Publsiher: Springer
Total Pages: 329
Release: 2021-04-10
ISBN 10: 9789813368262
ISBN 13: 9813368268
Language: EN, FR, DE, ES & NL

Targeting Cellular Signalling Pathways in Lung Diseases Book Review:

The book comprehensively reviews and provides detailed insight into the cellular and molecular signalling mechanisms involved in pathophysiology of various respiratory diseases, towards developing effective therapeutic strategies in the management and treatment of lung disease. It also covers promising advances in the field of therapeutics that could lead to novel clinical therapies capable of preventing or reversing the disease features including novel strategies for targeting chronic lung diseases using advanced drug delivery systems. Importantly, the book examines the significance and relevance of the plant extracts and their constituents with therapeutic efficiencies against lung diseases. As such, the book offers a blend of translational, biological, chemical, and drug delivery aspects relevant to respiratory diseases, thus, offering a valuable resource for pulmonologists and translational researchers working in the field of pulmonary biology and respiratory medicine.

Modeling and Control of Drug Delivery Systems

Modeling and Control of Drug Delivery Systems
Author: Ahmad Taher Azar
Publsiher: Academic Press
Total Pages: 408
Release: 2021-02-15
ISBN 10: 0128211954
ISBN 13: 9780128211953
Language: EN, FR, DE, ES & NL

Modeling and Control of Drug Delivery Systems Book Review:

Modeling and Control of Drug Delivery Systems provides comprehensive coverage of various drug delivery and targeting systems and their state-of-the-art related works, ranging from theory to real-world deployment and future perspectives. Various drug delivery and targeting systems have been developed to minimize drug degradation and adverse effect and increase drug bioavailability. Site-specific drug delivery may be either an active and/or passive process. Improving delivery techniques that minimize toxicity and increase efficacy offer significant potential benefits to patients and open up new markets for pharmaceutical companies. This book will attract many researchers working in DDS field as it provides an essential source of information for pharmaceutical scientists and pharmacologists working in academia as well as in the industry. In addition, it has useful information for pharmaceutical physicians and scientists in many disciplines involved in developing DDS, such as chemical engineering, biomedical engineering, protein engineering, gene therapy. Presents some of the latest innovations of approaches to DDS from dynamic controlled drug delivery, modeling, system analysis, optimization, control and monitoring Provides a unique, recent and comprehensive reference on DDS with the focus on cutting-edge technologies and the latest research trends in the area Covers the most recent works, in particular, the challenging areas related to modeling and control techniques applied to DDS

The Molecular Targets and Therapeutic Uses of Curcumin in Health and Disease

The Molecular Targets and Therapeutic Uses of Curcumin in Health and Disease
Author: Bharat B. Aggarwal,Young-Joon Surh,S. Shishodia
Publsiher: Springer Science & Business Media
Total Pages: 490
Release: 2007-08-06
ISBN 10: 0387464018
ISBN 13: 9780387464015
Language: EN, FR, DE, ES & NL

The Molecular Targets and Therapeutic Uses of Curcumin in Health and Disease Book Review:

The medicinal uses of Curcumin (also called turmeric) have been known and described for more than 5000 years. A large body of recent research suggests that curcumin is potentially useful in the treatment of inflammatory diseases, through modulation of numerous molecular targets. This is the first monograph to focus on the potential use of curcumin in the treatment of cancer, diabetes, cardiovascular diseases, arthritis, Alzheimer’s, psoriasis and more.

Drug Delivery to the Lung

Drug Delivery to the Lung
Author: Hans Bisgaard,Chris O'Callaghan,Gerald C. Smaldone
Publsiher: CRC Press
Total Pages: 536
Release: 2001-10-02
ISBN 10: 9780824741976
ISBN 13: 0824741978
Language: EN, FR, DE, ES & NL

Drug Delivery to the Lung Book Review:

This book focuses on the aerosol treatment of lung diseases, recent improvements in the understanding of proper dosage, and major innovations in device technology applied to clinical practice. Examines the behavior of inspired spherical particles in the respiratory tract! Featuring over 1300 references, drawings, tables, photographs,

Surface Modification of Nanoparticles for Targeted Drug Delivery

Surface Modification of Nanoparticles for Targeted Drug Delivery
Author: Yashwant V Pathak
Publsiher: Springer
Total Pages: 499
Release: 2019-03-11
ISBN 10: 3030061159
ISBN 13: 9783030061159
Language: EN, FR, DE, ES & NL

Surface Modification of Nanoparticles for Targeted Drug Delivery Book Review:

This unique book is the only one to discuss various new techniques developed to enhance the application of nanoparticulate drug delivery systems using surface modification of nanoparticles. The understanding of the surface characteristics nano-particles is growing significantly with the advent of new analytical techniques. Polymer chemistry is contributing to the development of many new versatile polymers which have abilities to accommodate many different, very reactive chemical groups, and can be used as a diagnostic tool, for better targeting, for more effective therapeutic results as well as for reducing the toxic and side effects of the drugs. Surface modification of such polymeric nanoparticles has been found by many scientists to enhance the application of nanoparticles and also allows the nano particles to carry specific drug molecule and disease /tumor specific antibodies which refine and improve drug delivery. Surface Modification of Nanoparticles for Targeted Drug Delivery is a collection essential information with various applications of surface modification of nanoparticles and their disease specific applications for therapeutic purposes.

Global Surveillance Prevention and Control of Chronic Respiratory Diseases

Global Surveillance  Prevention and Control of Chronic Respiratory Diseases
Author: World Health Organization
Publsiher: World Health Organization
Total Pages: 146
Release: 2007
ISBN 10: 924156346X
ISBN 13: 9789241563468
Language: EN, FR, DE, ES & NL

Global Surveillance Prevention and Control of Chronic Respiratory Diseases Book Review:

Chronic respiratory diseases, such as asthma and chronic obstructive pulmonary disease, kill more than 4 million people every year, and affect hundreds of millions more. These diseases erode the health and well-being of the patients and have a negative impact on families and societies. This report raises awareness of the huge impact of chronic respiratory diseases worldwide, and highlights the risk factors as well as ways to prevent and treat these diseases.

Proteases in Human Diseases

Proteases in Human Diseases
Author: Sajal Chakraborti,Tapati Chakraborti,Naranjan S. Dhalla
Publsiher: Springer
Total Pages: 513
Release: 2017-07-13
ISBN 10: 9811031622
ISBN 13: 9789811031625
Language: EN, FR, DE, ES & NL

Proteases in Human Diseases Book Review:

This book bridges the gap between fundamental research and biomedical and pharmacological applications on proteases. It represents a comprehensive overview of the multifaceted field of proteases in cellular environment and highlights the recently elucidated functions of complex proteolytic systems in different diseases. Several established investigators have elucidated the crucial role of proteases in biological processes, including how proteolytic function and regulation can be combined to develop new strategies of therapeutic interventions. Proteases form one of the largest and most diverse families of enzymes known. It is now clear that proteases are involved in every aspect of life functions of an organism. Under physiological conditions, proteases are regulated by their endogenous inhibitors; however, when the activity of proteases is not regulated appropriately, disease processes can result in. So, there is absolute need for a stringent control of proteolytic activities in cells and tissues. Dysregulation of proteases may cause derangement of cellular signalling network resulting in different pathophysiological conditions such as vascular remodelling, atherosclerotic plaque progression, ulcer and rheumatoid arthritis, Alzheimer disease, cancer metastasis, tumor progression and inflammation. Additionally, many infective microorganisms require proteases for replication or use proteases as virulence factors, which have facilitated the development of protease-targeted therapies for a variety of parasitic diseases.

Smart Drug Delivery System

Smart Drug Delivery System
Author: Ali Demir Sezer
Publsiher: BoD – Books on Demand
Total Pages: 398
Release: 2016-02-10
ISBN 10: 9535122479
ISBN 13: 9789535122470
Language: EN, FR, DE, ES & NL

Smart Drug Delivery System Book Review:

This contribution book collects reviews and original articles from eminent experts working in the interdisciplinary arena of novel drug delivery systems and their uses. From their direct and recent experience, the readers can achieve a wide vision on the new and ongoing potentialities of different smart drug delivery systems. Since the advent of analytical techniques and capabilities to measure particle sizes in nanometer ranges, there has been tremendous interest in the use of nanoparticles for more efficient methods of drug delivery. On the other hand, this reference discusses advances in the design, optimization, and adaptation of gene delivery systems for the treatment of cancer, cardiovascular, diabetic, genetic, and infectious diseases, and considers assessment and review procedures involved in the development of gene-based pharmaceuticals.

Lung Inflammation

Lung Inflammation
Author: Kian Chung Ong
Publsiher: BoD – Books on Demand
Total Pages: 120
Release: 2014-05-14
ISBN 10: 9535113739
ISBN 13: 9789535113737
Language: EN, FR, DE, ES & NL

Lung Inflammation Book Review:

In order to perform its function in gas exchange, the lungs and all components of the respiratory system are constantly exposed to pathogens, toxins, pollutants, irritants, and allergens in the environment. Lung inflammation involves an array of mechanisms to defend the lung against these extrinsic agents and to repair injured tissue. Additionally, the lungs are a frequent target at risk to conditions associated with systemic inflammation that cause multi-organ damage. The inflammatory reaction in the lung is a complex and dynamic process, and our understanding in this field is rapidly progressing. Further elucidation of the complexity of inflammation will likely improve the clinicians approach to as well as the treatment of a myriad of lung disorders. The chapters in this book are selected topics of current interest in lung inflammation.

Medicinal Plants for Lung Diseases

Medicinal Plants for Lung Diseases
Author: Kamal Dua,Srinivas Nammi,Dennis ` Chang,Dinesh Kumar Chellappan,Gaurav Gupta,Trudi Collet
Publsiher: Springer
Total Pages: 329
Release: 2021-05-29
ISBN 10: 9789813368491
ISBN 13: 9813368497
Language: EN, FR, DE, ES & NL

Medicinal Plants for Lung Diseases Book Review:

This book summarizes experimentally-supported research on the therapeutic efficacy of plant extracts and their constituents on respiratory diseases. It discusses the cellular and molecular factors involved in chronic obstructive pulmonary disease (COPD) and their modulation by plant-derived compounds. The book also highlights multiple health benefits of phytomedicine for treating asthma and COPD and also explores the mechanisms through which they exert the therapeutic effect. Additionally, it underlines the importance of medicinal plants in treating tuberculosis and influenza A virus infections. It reviews plant-derived chemical compounds that target different signaling pathways in chronic lung diseases. Lastly, the book introduces a medicinal plant-based advanced drug delivery system for treating chronic lung diseases.

Advances in Pulmonary Drug Delivery

Advances in Pulmonary Drug Delivery
Author: Philip Chi Lip Kwok,Hak-Kim Chan
Publsiher: CRC Press
Total Pages: 246
Release: 2016-12-19
ISBN 10: 131531195X
ISBN 13: 9781315311951
Language: EN, FR, DE, ES & NL

Advances in Pulmonary Drug Delivery Book Review:

The respiratory tract has been used to deliver biologically active chemicals into the human body for centuries. However, the lungs are complex in their anatomy and physiology, which poses challenges to drug delivery. Inhaled formulations are generally more sophisticated than those for oral and parenteral administration. Pulmonary drug development is therefore a highly specialized area because of its many unique issues and challenges. Rapid progress is being made and offers novel solutions to existing treatment problems. Advances in Pulmonary Drug Delivery highlights the latest developments in this field.

Targeted Drug Delivery Concepts and Design

Targeted Drug Delivery   Concepts and Design
Author: Padma V. Devarajan,Sanyog Jain
Publsiher: Springer
Total Pages: 790
Release: 2014-12-08
ISBN 10: 3319113550
ISBN 13: 9783319113555
Language: EN, FR, DE, ES & NL

Targeted Drug Delivery Concepts and Design Book Review:

This authoritative volume explores the fundamental concepts and numerous applications of targeted delivery of drugs to the body. This compilation has been divided into eight sections comprised of the basic principles of drug targeting, disease and organ/organelle-based targeting, passive and active targeting strategies, and various advanced drug delivery tools such as functionalized lipidic, polymeric and inorganic nanocarriers. Together, the twenty-three chapters cover a wide range of topics in the field, including tumor and hepatic targeting, polymer-drug conjugates, nanoemulsion, physical and biophysical characteristics of nanoparticles, and in vivo imaging techniques, among others. The book also examines advanced characterization techniques, regulatory hurdles and toxicity-related issues that are key features for successful commercialization of targeted drug delivery system products. Targeted Drug Delivery is a comprehensive reference guide for drug delivery researchers, both beginners and those already working in the field.

A Nationwide Framework for Surveillance of Cardiovascular and Chronic Lung Diseases

A Nationwide Framework for Surveillance of Cardiovascular and Chronic Lung Diseases
Author: Institute of Medicine,Board on Population Health and Public Health Practice,Committee on a National Surveillance System for Cardiovascular and Select Chronic Diseases
Publsiher: National Academies Press
Total Pages: 200
Release: 2011-08-26
ISBN 10: 0309212197
ISBN 13: 9780309212199
Language: EN, FR, DE, ES & NL

A Nationwide Framework for Surveillance of Cardiovascular and Chronic Lung Diseases Book Review:

Chronic diseases are common and costly, yet they are also among the most preventable health problems. Comprehensive and accurate disease surveillance systems are needed to implement successful efforts which will reduce the burden of chronic diseases on the U.S. population. A number of sources of surveillance data--including population surveys, cohort studies, disease registries, administrative health data, and vital statistics--contribute critical information about chronic disease. But no central surveillance system provides the information needed to analyze how chronic disease impacts the U.S. population, to identify public health priorities, or to track the progress of preventive efforts. A Nationwide Framework for Surveillance of Cardiovascular and Chronic Lung Diseases outlines a conceptual framework for building a national chronic disease surveillance system focused primarily on cardiovascular and chronic lung diseases. This system should be capable of providing data on disparities in incidence and prevalence of the diseases by race, ethnicity, socioeconomic status, and geographic region, along with data on disease risk factors, clinical care delivery, and functional health outcomes. This coordinated surveillance system is needed to integrate and expand existing information across the multiple levels of decision making in order to generate actionable, timely knowledge for a range of stakeholders at the local, state or regional, and national levels. The recommendations presented in A Nationwide Framework for Surveillance of Cardiovascular and Chronic Lung Diseases focus on data collection, resource allocation, monitoring activities, and implementation. The report also recommends that systems evolve along with new knowledge about emerging risk factors, advancing technologies, and new understanding of the basis for disease. This report will inform decision-making among federal health agencies, especially the Department of Health and Human Services; public health and clinical practitioners; non-governmental organizations; and policy makers, among others.

Nanotechnology and Drug Delivery Volume Two

Nanotechnology and Drug Delivery  Volume Two
Author: Jose L. Arias
Publsiher: CRC Press
Total Pages: 487
Release: 2016-04-21
ISBN 10: 1482262738
ISBN 13: 9781482262735
Language: EN, FR, DE, ES & NL

Nanotechnology and Drug Delivery Volume Two Book Review:

The recent introduction of nanomedicines in the drug therapy arena is revolutionizing the management of severe diseases. The key advance in the field is the optimization of the biological fate of drug molecules, thus improving the therapeutic effect while keeping to a very minimum the associated toxicity. Volume one of this book series, Nanoplatforms in Drug Delivery, established the basic aspects in the development of drug-loaded nanoplatforms, the so-called nanomedicines or nanodrugs, focusing on representative materials and strategies used in their formulation. Taking advantage of the advanced conceptualizations on nanomedicine engineering that were described in volume one, volume two, Nano-Engineering Strategies and Nanomedicines against Severe Diseases, analyzes in depth special features related to the formulation of nanoplatforms for oral, dental, topical and transdermal, pulmonary and nasal, ocular and otic, vaginal, and brain drug delivery and targeting. Particular aspects of nanomedicine engineering and in vivo fate associated with the routing of drug administration are given special attention. In addition, an up-to-date view is presented on the use of nanomedicines against severe diseases, such as cancer, cardiovascular diseases, neurodegenerative disorders, infectious diseases, chronic inflammatory diseases, and metabolic diseases. The chapters analyze the key factors that need to be controlled to achieve the optimum therapeutic effect. Attention is further given to gene delivery and the recent concept of nanotheranosis.

Application of Nanotechnology in Drug Delivery

Application of Nanotechnology in Drug Delivery
Author: Ali Demir Sezer
Publsiher: BoD – Books on Demand
Total Pages: 554
Release: 2014-07-25
ISBN 10: 9535116282
ISBN 13: 9789535116288
Language: EN, FR, DE, ES & NL

Application of Nanotechnology in Drug Delivery Book Review:

This book collects reviews and original articles from eminent experts working in the interdisciplinary arena of nanotechnology use in drug delivery. From their direct and recent experience, the readers can achieve a wide vision on the new and ongoing potentialities of nanotechnology application of drug delivery. Since the advent of analytical techniques and capabilities to measure particle sizes in nanometer ranges, there has been tremendous interest in the use of nanoparticles for more efficient methods of drug delivery. On the other hand, this reference discusses advances in design, optimization, and adaptation of gene delivery systems for the treatment of cancer, cardiovascular, pulmonary, genetic, and infectious diseases, and considers assessment and review procedures involved in the development of gene-based pharmaceuticals.

Nanoparticles in Biology and Medicine

Nanoparticles in Biology and Medicine
Author: Mikhail Soloviev
Publsiher: Humana
Total Pages: 555
Release: 2012-07-13
ISBN 10:
ISBN 13: UCR:31210020594394
Language: EN, FR, DE, ES & NL

Nanoparticles in Biology and Medicine Book Review:

The modern fascination with micro- and nano-sized materials can actually be traced back further to the 1960s and ‘70s when the first few reported attempts were made to use nanoparticles for controlled drug delivery. In Nanoparticles in Biology and Medicine: Methods and Protocols, experts in the field present a wide range of methods for synthesis, surface modification, characterization, and application of nano-sized materials (nanoparticles) in life science and medical fields, mostly for drug delivery. The methods presented cover all stages of nanoparticle manufacturing, modification, analysis, and applications. Written in the highly successful Methods in Molecular BiologyTM series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Comprehensive and cutting-edge, Nanoparticles in Biology and Medicine: Methods and Protocols will help the beginner become familiar with this fascinating field and will provide scientists at all levels of expertise with easy-to-follow practical advice needed to make, modify, and analyze nanoparticles of their choice and to use them in a wide range of biomedical and pharmaceutical applications, including functional protein studies, drug delivery, immunochemistry, imaging, and many others.

Immunotherapy

Immunotherapy
Author: Krassimir Metodiev
Publsiher: BoD – Books on Demand
Total Pages: 414
Release: 2017-04-26
ISBN 10: 9535131052
ISBN 13: 9789535131052
Language: EN, FR, DE, ES & NL

Immunotherapy Book Review:

This is another attempt of InTechOpen to continue the dissemination of international knowledge and experience in the field of immunology. The present book includes a number of modern concepts of specialists and experts in the field of immunotherapy, covering the major topics and analyzing the history, current stage, and future ideas of application of modern immunomodulation. It is always a benefit, but also a compliment, to gather a team of internationally distinguished authors and to motivate them to reveal their expertise for the benefit of medical science and health practice. On behalf of all readers, immunologists, immunogeneticists, biologists, oncologists, microbiologists, virologists, hematologists, chemotherapists, health-care experts, as well as students and medical specialists, also on my personal behalf, I would like to extend my gratitude and highest appreciation to InTechOpen for giving me the unique chance to be the editor of this exclusive book.

Nanotechnology in Modern Animal Biotechnology

Nanotechnology in Modern Animal Biotechnology
Author: Pawan Kumar Maurya,Sanjay Singh
Publsiher: Elsevier
Total Pages: 178
Release: 2019-07-20
ISBN 10: 0128188243
ISBN 13: 9780128188248
Language: EN, FR, DE, ES & NL

Nanotechnology in Modern Animal Biotechnology Book Review:

Nanotechnology in Modern Animal Biotechnology: Concepts and Applications discusses the advancement of nanotechnologies in almost every field, ranging from materials science, to food, forensic, agriculture and life sciences, including biotechnology and medicine. Nanotechnology is already being harnessed to address many of the key problems in animal biotechnology, with future applications covering animal biotechnology (e.g. animal nutrition, health, disease diagnosis, and drug delivery). This book provides the tools, ideas and techniques of nanoscale principles to investigate, understand and transform biological systems. Nanotechnology provides the ability to manipulate materials at atomic and molecular levels and also arrange atom-by-atom on a scale of ∼1–100 nm to create, new materials and devices with fundamentally new functions and properties arising due to their small scale. Details the basics of nanotechnology, along with comprehensive information on the state-of-the-art and future perspectives of nanotechnology in biosensors Provides recent perspectives and the challenges of nanomedicine Provides new insights into the role nanomaterials can play in curing various diseases Includes the most recent diagnostic methods, such as nanosensors

Lung Epithelial Biology in the Pathogenesis of Pulmonary Disease

Lung Epithelial Biology in the Pathogenesis of Pulmonary Disease
Author: Venkataramana K Sidhaye,Michael Koval
Publsiher: Academic Press
Total Pages: 276
Release: 2017-03-09
ISBN 10: 0128038810
ISBN 13: 9780128038819
Language: EN, FR, DE, ES & NL

Lung Epithelial Biology in the Pathogenesis of Pulmonary Disease Book Review:

Lung Epithelial Biology in the Pathogenesis of Pulmonary Disease provides a one-stop resource capturing developments in lung epithelial biology related to basic physiology, pathophysiology, and links to human disease. The book provides access to knowledge of molecular and cellular aspects of lung homeostasis and repair, including the molecular basis of lung epithelial intercellular communication and lung epithelial channels and transporters. Also included is coverage of lung epithelial biology as it relates to fluid balance, basic ion/fluid molecular processes, and human disease. Useful to physician and clinical scientists, the contents of this book compile the important and most current findings about the role of epithelial cells in lung disease. Medical and graduate students, postdoctoral and clinical fellows, as well as clinicians interested in the mechanistic basis for lung disease will benefit from the books examination of principles of lung epithelium functions in physiological condition. Provides a single source of information on lung epithelial junctions and transporters Discusses of the role of the epithelium in lung homeostasis and disease Includes capsule summaries of main conclusions as well as highlights of future directions in the field Covers the mechanistic basis for lung disease for a range of audiences