Systems and Synthetic Metabolic Engineering

Systems and Synthetic Metabolic Engineering
Author: Yanfeng Liu,Guocheng Du,Long Liu
Publsiher: Academic Press
Total Pages: 294
Release: 2020-07-10
ISBN 10: 0128217529
ISBN 13: 9780128217528
Language: EN, FR, DE, ES & NL

Systems and Synthetic Metabolic Engineering Book Review:

Systems and Synthetic Metabolic Engineering provides an overview of the development of metabolic engineering within medicine that is fueled by systems and synthetic biology. These newly developed, successful strategies of metabolic engineering guide the audience on how to propose and test proper strategies for metabolic engineering research. In addition to introductory, regulatory and challenges in the field, the book also covers dynamic control and autonomous regulation to control cell metabolism, along with computational modeling and industrial applications. The book is written by leaders in the field, making it ideal for synthetic biologists, researchers, students and anyone working in this area. Discusses the current progress of metabolic engineering, focusing on systems biology and synthetic biology Covers introductory, regulatory, strategies, production and challenges in the field Written technically for synthetic biologists, researchers, students, industrialists, policymakers and stakeholders

Systems Metabolic Engineering

Systems Metabolic Engineering
Author: Christoph Wittmann,Sang Yup Lee
Publsiher: Springer Science & Business Media
Total Pages: 388
Release: 2012-06-15
ISBN 10: 9400745346
ISBN 13: 9789400745346
Language: EN, FR, DE, ES & NL

Systems Metabolic Engineering Book Review:

Systems Metabolic Engineering is changing the way microbial cell factories are designed and optimized for industrial production. Integrating systems biology and biotechnology with new concepts from synthetic biology enables the global analysis and engineering of microorganisms and bioprocesses at super efficiency and versatility otherwise not accessible. Without doubt, systems metabolic engineering is a major driver towards bio-based production of chemicals, materials and fuels from renewables and thus one of the core technologies of global green growth. In this book, Christoph Wittmann and Sang-Yup Lee have assembled the world leaders on systems metabolic engineering and cover the full story – from genomes and networks via discovery and design to industrial implementation practises. This book is a comprehensive resource for students and researchers from academia and industry interested in systems metabolic engineering. It provides us with the fundaments to targeted engineering of microbial cells for sustainable bio-production and stimulates those who are interested to enter this exiting research field.

Yeast Metabolic Engineering

Yeast Metabolic Engineering
Author: Valeria Mapelli
Publsiher: Humana Press
Total Pages: 316
Release: 2014-04-18
ISBN 10: 9781493905621
ISBN 13: 1493905627
Language: EN, FR, DE, ES & NL

Yeast Metabolic Engineering Book Review:

Yeast Metabolic Engineering: Methods and Protocols provides the widely established basic tools used in yeast metabolic engineering, while describing in deeper detail novel and innovative methods that have valuable potential to improve metabolic engineering strategies in industrial biotechnology applications. Beginning with an extensive section on molecular tools and technology for yeast engineering, this detailed volume is not limited to methods for Saccharomyces cerevisiae, but describes tools and protocols for engineering other yeasts of biotechnological interest, such as Pichia pastoris, Hansenula polymorpha and Zygosaccharomyces bailii. Tools and technologies for the investigation and determination of yeast metabolic features are described in detail as well as metabolic models and their application for yeast metabolic engineering, while a chapter describing patenting and regulations with a special glance at yeast biotechnology closes the volume. Written in the highly successful Methods in Molecular Biology series format, most chapters include an introduction to their respective topic, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols and tips on troubleshooting and avoiding known pitfalls. Comprehensive and authoritative, Yeast Metabolic Engineering: Methods and Protocols aims to familiarize researchers with the current state of these vital and increasingly useful technologies.

Systems Biology and Synthetic Biology

Systems Biology and Synthetic Biology
Author: Pengcheng Fu,Sven Panke
Publsiher: John Wiley & Sons
Total Pages: 672
Release: 2009-08-13
ISBN 10: 9780470437971
ISBN 13: 0470437979
Language: EN, FR, DE, ES & NL

Systems Biology and Synthetic Biology Book Review:

The genomic revolution has opened up systematic investigations and engineering designs for various life forms. Systems biology and synthetic biology are emerging as two complementary approaches, which embody the breakthrough in biology and invite application of engineering principles. Systems Biology and Synthetic Biology emphasizes the similarity between biology and engineering at the system level, which is important for applying systems and engineering theories to biology problems. This book demonstrates to students, researchers, and industry that systems biology relies on synthetic biology technologies to study biological systems, while synthetic biology depends on knowledge obtained from systems biology approaches.

Synthetic Biology Metabolic Engineering

Synthetic Biology     Metabolic Engineering
Author: Huimin Zhao,An-Ping Zeng
Publsiher: Springer
Total Pages: 322
Release: 2017-10-27
ISBN 10: 3319553186
ISBN 13: 9783319553184
Language: EN, FR, DE, ES & NL

Synthetic Biology Metabolic Engineering Book Review:

This book review series presents current trends in modern biotechnology. The aim is to cover all aspects of this interdisciplinary technology where knowledge, methods and expertise are required from chemistry, biochemistry, microbiology, genetics, chemical engineering and computer science. Volumes are organized topically and provide a comprehensive discussion of developments in the respective field over the past 3-5 years. The series also discusses new discoveries and applications. Special volumes are dedicated to selected topics which focus on new biotechnological products and new processes for their synthesis and purification. In general, special volumes are edited by well-known guest editors. The series editor and publisher will however always be pleased to receive suggestions and supplementary information. Manuscripts are accepted in English.

Synthetic Biology Guided Metabolic Engineering

Synthetic Biology Guided Metabolic Engineering
Author: Rodrigo Ledesma-Amaro,Pablo Ivan Nikel,Francesca Ceroni
Publsiher: Frontiers Media SA
Total Pages: 135
Release: 2020-05-05
ISBN 10: 2889637085
ISBN 13: 9782889637089
Language: EN, FR, DE, ES & NL

Synthetic Biology Guided Metabolic Engineering Book Review:

Systems and Synthetic Biotechnology for Production of Nutraceuticals

Systems and Synthetic Biotechnology for Production of Nutraceuticals
Author: Long Liu,Jian Chen
Publsiher: Springer Nature
Total Pages: 208
Release: 2020-01-03
ISBN 10: 9811504466
ISBN 13: 9789811504464
Language: EN, FR, DE, ES & NL

Systems and Synthetic Biotechnology for Production of Nutraceuticals Book Review:

This book discusses systems and synthetic biotechnologies for the production of nutraceuticals, and summarizes recent advances in nutraceutical research in terms of the physiological effects on health, potential applications, drawbacks of traditional production processes, characteristics of production strains, and advances in microbial production based on systems and synthetic biotechnology. It also examines future directions in the microbial production of nutraceuticals using systems and synthetic biology. The book is intended for researchers and graduate students in the field of molecular biology and industrial biotechnology as well as staff working in the nutraceutical industry.

Microbial Cell Factories Engineering for Production of Biomolecules

Microbial Cell Factories Engineering for Production of Biomolecules
Author: Vijai Singh
Publsiher: Academic Press
Total Pages: 488
Release: 2021-02-26
ISBN 10: 0128214783
ISBN 13: 9780128214787
Language: EN, FR, DE, ES & NL

Microbial Cell Factories Engineering for Production of Biomolecules Book Review:

Microbial Cell Factories Engineering for Production of Biomolecules presents a compilation of chapters written by eminent scientists worldwide. Sections cover major tools and technologies for DNA synthesis, design of biosynthetic pathways, synthetic biology tools, biosensors, cell-free systems, computer-aided design, OMICS tools, CRISPR/Cas systems, and many more. Although it is not easy to find relevant information collated in a single volume, the book covers the production of a wide range of biomolecules from several MCFs, including Escherichia coli, Bacillus subtilis, Pseudomonas putida, Streptomyces, Corynebacterium, Cyanobacteria, Saccharomyces cerevisiae, Pichia pastoris and Yarrowia lipolytica, and algae, among many others. This will be an excellent platform from which scientific knowledge can grow and widen in MCF engineering research for the production of biomolecules. Needless to say, the book is a valuable source of information not only for researchers designing cell factories, but also for students, metabolic engineers, synthetic biologists, genome engineers, industrialists, stakeholders and policymakers interested in harnessing the potential of MCFs in several fields. Offers basic understanding and a clear picture of various MCFs Explains several tools and technologies, including DNA synthesis, synthetic biology tools, genome editing, biosensors, computer-aided design, and OMICS tools, among others Harnesses the potential of engineered MCFs to produce a wide range of biomolecules for industrial, therapeutic, pharmaceutical, nutraceutical and biotechnological applications Highlights the advances, challenges, and future opportunities in designing MCFs

Industrial Biotechnology

Industrial Biotechnology
Author: Christoph Wittmann,James C. Liao,Sang Yup Lee,Jens Nielsen,Gregory Stephanopoulos
Publsiher: John Wiley & Sons
Total Pages: 792
Release: 2017-04-10
ISBN 10: 352734179X
ISBN 13: 9783527341795
Language: EN, FR, DE, ES & NL

Industrial Biotechnology Book Review:

The latest volume in the Advanced Biotechnology series provides an overview of the main production hosts and platform organisms used today as well as promising future cell factories in a two volume book. Alongside describing tools for genetic and metabolic engineering for strain improvement, the authors also impart topical information on computational tools, safety aspects and industrial-scale production. Following an introduction to general concepts, historical developments and future technologies, the text goes on to cover multi-purpose bacterial cell factories, including those organisms that exploit anaerobic biosynthetic power. Further chapters deal with microbes used for the production of high-value natural compounds and those obtained from alternative raw material sources, concluding with eukaryotic workhorses. Of interest to biotechnologists and microbiologists, as well as those working in the biotechnological, chemical, food and pharmaceutical industries.The latest volume in the Advanced Biotechnology series provides an overview of the main production hosts and platform organisms used today as well as promising future cell factories in a two volume book. Alongside describing tools for genetic and metabolic engineering for strain improvement, the authors also impart topical information on computational tools, safety aspects and industrial-scale production. Following an introduction to general concepts, historical developments and future technologies, the text goes on to cover multi-purpose bacterial cell factories, including those organisms that exploit anaerobic biosynthetic power. Further chapters deal with microbes used for the production of high-value natural compounds and those obtained from alternative raw material sources, concluding with eukaryotic workhorses. Of interest to biotechnologists and microbiologists, as well as those working in the biotechnological, chemical, food and pharmaceutical industries.

Metabolic Engineering Synthetic Biology and Systems Biology

Metabolic Engineering  Synthetic Biology and Systems Biology
Author: Anonim
Publsiher: Unknown
Total Pages: 163
Release: 2012
ISBN 10: 1928374650XXX
ISBN 13: OCLC:785833307
Language: EN, FR, DE, ES & NL

Metabolic Engineering Synthetic Biology and Systems Biology Book Review:

Metabolic Engineering

Metabolic Engineering
Author: Sang Yup Lee,Jens Nielsen,Gregory Stephanopoulos
Publsiher: John Wiley & Sons
Total Pages: 976
Release: 2021-06-02
ISBN 10: 352782345X
ISBN 13: 9783527823451
Language: EN, FR, DE, ES & NL

Metabolic Engineering Book Review:

Learn more about foundational and advanced topics in metabolic engineering in this comprehensive resource edited by leaders in the field Metabolic Engineering: Concepts and Applications delivers a one-stop resource for readers seeking a complete description of the concepts, models, and applications of metabolic engineering. This guide offers practical insights into the metabolic engineering of major cell lines, including E. Coli, Bacillus and Yarrowia Lipolytica, and organisms, including human, animal, and plant). The distinguished editors also offer readers resources on microbiome engineering and the use of metabolic engineering in bioremediation. Written in two parts, Metabolic Engineering begins with the essential models and strategies of the field, like Flux Balance Analysis, Quantitative Flux Analysis, and Proteome Constrained Models. It also provides an overview of topics like Pathway Design, Metabolomics, and Genome Editing of Bacteria and Eukarya. The second part contains insightful descriptions of the practical applications of metabolic engineering, including specific examples that shed light on the topics within. In addition to subjects like the metabolic engineering of animals, humans, and plants, you’ll learn more about: Metabolic engineering concepts and a historical perspective on their development The different modes of analysis, including flux balance analysis and quantitative flux analysis An illuminating and complete discussion of the thermodynamics of metabolic pathways The Genome architecture of E. coli, as well as genome editing of both bacteria and eukarya An in-depth treatment of the application of metabolic engineering techniques to organisms including corynebacterial, bacillus, and pseudomonas, and more Perfect for students of biotechnology, bioengineers, and biotechnologists, Metabolic Engineering: Concepts and Applications also has a place on the bookshelves of research institutes, biotechnological institutes and industry labs, and university libraries. It's comprehensive treatment of all relevant metabolic engineering concepts, models, and applications will be of use to practicing biotechnologists and bioengineers who wish to solidify their understanding of the field.

Synthetic Metabolic Pathways

Synthetic Metabolic Pathways
Author: Michael Krogh Jensen,Jay D. Keasling
Publsiher: Humana Press
Total Pages: 354
Release: 2017-11-24
ISBN 10: 9781493972944
ISBN 13: 1493972944
Language: EN, FR, DE, ES & NL

Synthetic Metabolic Pathways Book Review:

This volume outlines key steps associated with the design, building, and testing of synthetic metabolic pathways for optimal cell factory performance and robustness, and illustrates how data-driven learning from these steps can be used for rational cost-effective engineering of cell factories with improved performance. Chapters are divided into four sections focusing on the four steps of the iterative design-build-test-learn cycle related to modern cell factory engineering. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Synthetic Metabolic Pathways: Methods and Protocols aims to ensure successful results in the further study of this vital field.

Systems Biology

Systems Biology
Author: Bor-Sen Chen,Chia-Chou Wu
Publsiher: Unknown
Total Pages: 275
Release: 2014-01-01
ISBN 10: 9781633215887
ISBN 13: 1633215881
Language: EN, FR, DE, ES & NL

Systems Biology Book Review:

Systems biology sits at the heart of new integrative paradigm in the 21st century, the book could gain an insight into (i) system structure and the mechanism of biological networks such as gene regulation, protein interactions, signaling, and metabolic pathways; (ii) system dynamics of biological networks, which provides an understanding of stability, robustness, and transduction ability through system identification, and through system analysis methods; (iii) system control methods at different levels of biological networks, which provide an understanding of systematic mechanisms to robustly control system states, minimize malfunctions, and provide potential therapeutic targets in disease treatment; (iv) systematic design methods for the modification and construction of biological networks with desired behaviors, which provide system design principles and system simulations for synthetic biology designs and systems metabolic engineering. This book not only describes the current developments in systems biology, systems synthetic biology, and systems metabolic engineering for engineering and biology researchers but also discusses challenges and future prospects for systems biology and the concept of systems biology as an integrated platform for bioinformatics, systems synthetic biology, and systems metabolic engineering.

Metabolic Pathway Engineering

Metabolic Pathway Engineering
Author: Jean F. Challacombe
Publsiher: CRC Press
Total Pages: 156
Release: 2021-07-15
ISBN 10: 1000260542
ISBN 13: 9781000260540
Language: EN, FR, DE, ES & NL

Metabolic Pathway Engineering Book Review:

Metabolic systems engineering combines the tools and approaches of systems biology, synthetic biology, and evolutionary engineering. This book reviews studies on metabolism, from the earliest work of Lavoisier and Buchner to current cutting-edge research in metabolic systems engineering. This technology has been used in bioengineering applications to create high-performing microbes and plants that produce important chemicals, pharmaceuticals, crops, and other natural products. Current applications include optimizing metabolic pathways to enhance degradation of biomass for biofuel production and accelerated processing of environmental waste products and contaminants. The book includes examples to illustrate the applications of this technology in the optimization of metabolic pathways to create robust industrial strains as well as in the engineering of biological processes involving health and diseases of humans, animals, and plants. Written by a seasoned computational biologist with many years of experience in genomics, bioinformatics, and systems biology, this book will appeal to anyone interested in metabolic systems analysis and metabolic pathway engineering.

Systems Biology and Biotechnology of Escherichia coli

Systems Biology and Biotechnology of Escherichia coli
Author: Sang Yup Lee
Publsiher: Springer Science & Business Media
Total Pages: 462
Release: 2009-03-20
ISBN 10: 1402093942
ISBN 13: 9781402093944
Language: EN, FR, DE, ES & NL

Systems Biology and Biotechnology of Escherichia coli Book Review:

Systems biology is changing the way biological systems are studied by allowing us to examine the cell and organism as a whole. Systems biotechnology allows optimal design and development of upstream to downstream bioprocesses by taking a systems-approach. E. coli has been a model organism for almost all biological and biotechnological studies. This book brings together for the first time the state-of-the-art reviews by the world-leading experts on systems biology and biotechnological applications of E. coli. The topics covered include genomics and functional genomics, resources for systems biology, network analysis, genome-scale metabolic reconstruction, modelling and simulation, dynamic modelling and simulation, systems-level analysis of evolution, plasmids and expression systems, protein synthesis, production and export, engineering the central metabolism, synthetic biology, and systems metabolic engineering of E. coli. This book provides readers with guidance on how a complex biological system can be studied using E. coli as a model organism. It also presents how to perform synthetic biology and systems metabolic engineering studies on E. coli with successful examples, the approaches of which can be extended to other organisms. This book will be a complete resource for anyone interested in systems biology and biotechnology.

The Science and Applications of Synthetic and Systems Biology

The Science and Applications of Synthetic and Systems Biology
Author: Institute of Medicine,Board on Global Health,Forum on Microbial Threats
Publsiher: National Academies Press
Total Pages: 570
Release: 2011-12-30
ISBN 10: 0309219396
ISBN 13: 9780309219396
Language: EN, FR, DE, ES & NL

The Science and Applications of Synthetic and Systems Biology Book Review:

Many potential applications of synthetic and systems biology are relevant to the challenges associated with the detection, surveillance, and responses to emerging and re-emerging infectious diseases. On March 14 and 15, 2011, the Institute of Medicine's (IOM's) Forum on Microbial Threats convened a public workshop in Washington, DC, to explore the current state of the science of synthetic biology, including its dependency on systems biology; discussed the different approaches that scientists are taking to engineer, or reengineer, biological systems; and discussed how the tools and approaches of synthetic and systems biology were being applied to mitigate the risks associated with emerging infectious diseases. The Science and Applications of Synthetic and Systems Biology is organized into sections as a topic-by-topic distillation of the presentations and discussions that took place at the workshop. Its purpose is to present information from relevant experience, to delineate a range of pivotal issues and their respective challenges, and to offer differing perspectives on the topic as discussed and described by the workshop participants. This report also includes a collection of individually authored papers and commentary.

Synthetic Biology and Metabolic Engineering in Plants and Microbes Part B Metabolism in Plants

Synthetic Biology and Metabolic Engineering in Plants and Microbes Part B  Metabolism in Plants
Author: Sarah E. O'Connor
Publsiher: Academic Press
Total Pages: 446
Release: 2016-08-22
ISBN 10: 9780128045398
ISBN 13: 0128045396
Language: EN, FR, DE, ES & NL

Synthetic Biology and Metabolic Engineering in Plants and Microbes Part B Metabolism in Plants Book Review:

" Synthetic Biology and Metabolic Engineering in Plants and Microbes, Part B," the latest volume in the "Methods in Enzymology "series, " "continues the legacy of this premier serial with quality chapters authored by leaders in the field. This volume covers research methods, synthetic biology, and metabolic engineering in plants and microbes, and includes sections on such topics as the usage of integrases in microbial engineering, biosynthesis, and engineering of tryptophan derived metabolites, regulation and discovery of fungal natural products, and elucidation and localization of plant pathways. Continues the legacy of this premier serial with quality chapters authored by leaders in the field of enzymologyContains two volumes covering research methods in synthetic biology and metabolic engineering in plants and microbesIncludes sections on such topics as the uses of integrases in microbial engineering, biosynthesis and engineering of tryptophan derived metabolites, regulation and discovery of fungal natural products, and elucidation and localization of plant pathways

Synthetic Biology of Yeasts

Synthetic Biology of Yeasts
Author: Farshad Darvishi Harzevili
Publsiher: Springer
Total Pages: 135
Release: 2022-01-14
ISBN 10: 9783030896799
ISBN 13: 303089679X
Language: EN, FR, DE, ES & NL

Synthetic Biology of Yeasts Book Review:

This book covers recent advances and future trends in yeast synthetic biology, providing readers with an overview of computational and engineering tools, and giving insight on important applications. Yeasts are one of the most attractive microbial cell factories for the production of a wide range of valuable products, including pharmaceuticals, nutraceuticals, cosmetics, agrochemicals and biofuels. Synthetic biology tools have been developed to improve the metabolic engineering of yeasts in a faster and more reliable manner. Today, these tools are used to make synthetic pathways and rewiring metabolism even more efficient, producing products at high titer, rate, and yield. Split into two parts, the book opens with an introduction to rational metabolic pathway prediction and design using computational tools and their applications for yeast systems and synthetic biology. Then, it focuses on the construction and assembly of standardized biobricks for synthetic pathway engineering in yeasts, yeast cell engineering and whole cell yeast-based biosensors. The second part covers applications of synthetic biology to produce diverse and attractive products by some well-known yeasts. Given its interdisciplinary scope, the book offers a valuable asset for students, researchers and engineers working in biotechnology, applied microbiology, metabolic engineering and synthetic biology.

Cyanobacteria Biotechnology

Cyanobacteria Biotechnology
Author: Paul Hudson
Publsiher: John Wiley & Sons
Total Pages: 560
Release: 2021-04-20
ISBN 10: 3527824928
ISBN 13: 9783527824922
Language: EN, FR, DE, ES & NL

Cyanobacteria Biotechnology Book Review:

Unites a biological and a biotechnological perspective on cyanobacteria, and includes the industrial aspects and applications of cyanobacteria Cyanobacteria Biotechnology offers a guide to the interesting and useful features of cyanobacteria metabolism that keeps true to a biotechnology vision. In one volume the book brings together both biology and biotechnology to illuminate the core acpects and principles of cyanobacteria metabolism. Designed to offer a practical approach to the metabolic engineering of cyanobacteria, the book contains relevant examples of how this metabolic "module" is currently being engineered and how it could be engineered in the future. The author includes information on the requirements and real-world experiences of the industrial applications of cyanobacteria. This important book: Brings together biology and biotechnology in order to gain insight into the industrial relevant topic of cyanobacteria Introduces the key aspects of the metabolism of cyanobacteria Presents a grounded, practical approach to the metabolic engineering of cyanobacteria Offers an analysis of the requirements and experiences for industrial cyanobacteria Provides a framework for readers to design their own processes Written for biotechnologists, microbiologists, biologists, biochemists, Cyanobacteria Biotechnology provides a systematic and clear volume that brings together the biological and biotechnological perspective on cyanobacteria.

Metabolic Pathway Design

Metabolic Pathway Design
Author: Pablo Carbonell
Publsiher: Springer Nature
Total Pages: 168
Release: 2019-11-05
ISBN 10: 3030298655
ISBN 13: 9783030298654
Language: EN, FR, DE, ES & NL

Metabolic Pathway Design Book Review:

This textbook presents solid tools for in silico engineering biology, offering students a step-by-step guide to mastering the smart design of metabolic pathways. The first part explains the Design-Build-Test-Learn-cycle engineering approach to biology, discussing the basic tools to model biological and chemistry-based systems. Using these basic tools, the second part focuses on various computational protocols for metabolic pathway design, from enzyme selection to pathway discovery and enumeration. In the context of industrial biotechnology, the final part helps readers understand the challenges of scaling up and optimisation. By working with the free programming language Scientific Python, this book provides easily accessible tools for studying and learning the principles of modern in silico metabolic pathway design. Intended for advanced undergraduates and master’s students in biotechnology, biomedical engineering, bioinformatics and systems biology students, the introductory sections make it also useful for beginners wanting to learn the basics of scientific coding and find real-world, hands-on examples.