Synthetic Biology

Synthetic Biology
Author: Huimin Zhao
Publsiher: Academic Press
Total Pages: 352
Release: 2013-03-21
ISBN 10: 0123978203
ISBN 13: 9780123978202
Language: EN, FR, DE, ES & NL

Synthetic Biology Book Review:

Synthetic Biology provides a framework to examine key enabling components in the emerging area of synthetic biology. Chapters contributed by leaders in the field address tools and methodologies developed for engineering biological systems at many levels, including molecular, pathway, network, whole cell, and multi-cell levels. The book highlights exciting practical applications of synthetic biology such as microbial production of biofuels and drugs, artificial cells, synthetic viruses, and artificial photosynthesis. The roles of computers and computational design are discussed, as well as future prospects in the field, including cell-free synthetic biology and engineering synthetic ecosystems. Synthetic biology is the design and construction of new biological entities, such as enzymes, genetic circuits, and cells, or the redesign of existing biological systems. It builds on the advances in molecular, cell, and systems biology and seeks to transform biology in the same way that synthesis transformed chemistry and integrated circuit design transformed computing. The element that distinguishes synthetic biology from traditional molecular and cellular biology is the focus on the design and construction of core components that can be modeled, understood, and tuned to meet specific performance criteria and the assembly of these smaller parts and devices into larger integrated systems that solve specific biotechnology problems. Includes contributions from leaders in the field presents examples of ambitious synthetic biology efforts including creation of artificial cells from scratch, cell-free synthesis of chemicals, fuels, and proteins, engineering of artificial photosynthesis for biofuels production, and creation of unnatural living organisms Describes the latest state-of-the-art tools developed for low-cost synthesis of ever-increasing sizes of DNA and efficient modification of proteins, pathways, and genomes Highlights key technologies for analyzing biological systems at the genomic, proteomic, and metabolomic levels which are especially valuable in pathway, whole cell, and multi-cell applications Details mathematical modeling tools and computational tools which can dramatically increase the speed of the design process as well as reduce the cost of development.

Synthetic Biology

Synthetic Biology
Author: Lewis D. Solomon
Publsiher: Transaction Publishers
Total Pages: 174
Release: 2011-12-31
ISBN 10: 1412846471
ISBN 13: 9781412846479
Language: EN, FR, DE, ES & NL

Synthetic Biology Book Review:

For nearly forty years, using recombinant DNA tools, researchers, and then businesses, have genetically engineered organisms by transferring naturally occurring genes from one organism into another. Doing so modifies the genetic code of living cells, imparting new traits and achieving desired results; this is done in the production of proteins, pharmaceuticals, and seeds. Synthetic biology, argues Solomon, could free scientists from the need to find natural genes to make such desired modifications. Synthetic biology permits more complex and sophisticated bioengineering than what can be achieved through previous genetic modification techniques. Drawing on non-biological scientific and engineering disciplines, including information technology and nanotechnology, synthetic biology strives to rearrange an organism’s genes on a far wider scale by rewriting its genetic code, the chemical instructions need to design, assemble, and operate a species. By allowing the writing of artificial genetic codes, synthetic biology can transform existing industries and spawn new ones, creating new products as well as radically reshaping existing items. Arguing for self-regulation by the scientific and business communities, Lewis D. Solomon recommends a policy framework that would guard against governmental overregulation, which could create a barrier to innovation. Although synthetic biotechnology holds considerable social and economic potential, absent a nurturing regulatory climate, it may prove difficult to translate research discoveries into commercially viable applications.

Synthetic Biology

Synthetic Biology
Author: Christina Smolke,Sang Yup Lee,Jens Nielsen,Gregory Stephanopoulos
Publsiher: John Wiley & Sons
Total Pages: 432
Release: 2018-05-14
ISBN 10: 3527330755
ISBN 13: 9783527330751
Language: EN, FR, DE, ES & NL

Synthetic Biology Book Review:

need new text The inaugural volume of this new reference work in biotechnology is the most comprehensive of its kind on the market, covering everything from DNA synthesis to RNA interference and biosensors. Edited by the renowned scientists Sven Panke of the Swiss Federal Institute of Technology and Christina Smolke from Stanford University.

Synthetic Biology

Synthetic Biology
Author: Karen M. Polizzi,Cleo Kontoravdi
Publsiher: Unknown
Total Pages: 226
Release: 2013
ISBN 10: 9781627036252
ISBN 13: 1627036253
Language: EN, FR, DE, ES & NL

Synthetic Biology Book Review:

In Synthetic Biology, expert researchers in the field provide the latest developments in molecular biology techniques used in Synthetic Biology. Focusing on computational tools that will aid in systematising the design and construction of parts and systems. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Synthetic Biology seeks to aid scientists in the further study of developing new biological components and systems.

Synthetic Biology Handbook

Synthetic Biology Handbook
Author: Darren N. Nesbeth
Publsiher: CRC Press
Total Pages: 318
Release: 2016-04-06
ISBN 10: 1466568488
ISBN 13: 9781466568488
Language: EN, FR, DE, ES & NL

Synthetic Biology Handbook Book Review:

The Synthetic Biology Handbook explains the major goals of the field of synthetic biology and presents the technical details of the latest advances made in achieving those goals. Offering a comprehensive overview of the current areas of focus in synthetic biology, this handbook: Explores the standardisation of classic molecular bioscience approaches Addresses the societal context and potential impacts of synthetic biology Discusses the use of legacy systems as tools for new product development Examines the design and construction of de novo cells and genetic codes Describes computational methods for designing genes and gene networks Thus, the Synthetic Biology Handbook provides an accurate sense of the scope of synthetic biology today. The handbook also affords readers with an opportunity to scrutinize the underlying science and decide for themselves what aspects of synthetic biology are most valuable to their research and practice.

Synthetic Biology

Synthetic Biology
Author: Christopher Voigt,Christopher A. Voigt
Publsiher: Academic Press
Total Pages: 662
Release: 2011
ISBN 10: 0123850754
ISBN 13: 9780123850751
Language: EN, FR, DE, ES & NL

Synthetic Biology Book Review:

Synthetic biology encompasses a variety of different approaches, methodologies and disciplines, and many different definitions exist. This Volume of Methods in Enzymology has been split into 2 Parts and covers topics such as Measuring and Engineering Central Dogma Processes, Mathematical and Computational Methods and Next-Generation DNA Assembly and Manipulation. Encompasses a variety of different approaches, methodologies and disciplines Split into 2 parts and covers topics such as measuring and engineering central dogma processes, mathematical and computational methods and next-generation DNA assembly and manipulation

Synthetic Biology

Synthetic Biology
Author: Clyde A. Hutchinson, III,Daniel G. Gibson,J. Craig Venter,Hamilton O. Smith
Publsiher: Perspectives Cshl
Total Pages: 350
Release: 2017-04-30
ISBN 10: 9781621821182
ISBN 13: 1621821188
Language: EN, FR, DE, ES & NL

Synthetic Biology Book Review:

Synthetic biology involves the rational design and construction of biological components and systemsfrom genetic elements and metabolic pathways to entirely new organisms. Progress in this field has been rapid, and it promises to significantly expand our capabilities in biotechnology, medicine, and agriculture. Written and edited by experts in the field, this collection from Cold Spring Harbor Perspectives in Biology examines the tools and techniques employed by synthetic biologists, how these may be used to develop new drugs, diagnostic approaches, food sources, and clean energy, and what the field of synthetic biology has taught us about natural living systems. The contributors discuss advances in DNA synthesis and assembly, genome editing (e.g., CRISPR/Cas9), and artificial genetic systems. Progress in designing complex genetic switches and circuits, expanding the genetic code, modifying cellular organization, producing proteins using cell-free systems, and developing biodesign automation tools is also covered. The authors also explore ways to produce new organisms and products that have particular attributesfor example, microbial "molecular factories," synthetic organs and tissues, and plants with novel traits. This volume is an essential resource for molecular, cell, and systems biologists who seek to engineer living systems for human benefit.

Synthetic Biology a Primer revised Edition

Synthetic Biology   a Primer  revised Edition
Author: Paul S. FREEMONT,Richard I. KITNEY
Publsiher: World Scientific
Total Pages: 196
Release: 2015-08-24
ISBN 10: 1783268808
ISBN 13: 9781783268801
Language: EN, FR, DE, ES & NL

Synthetic Biology a Primer revised Edition Book Review:

Advances in Synthetic Biology

Advances in Synthetic Biology
Author: Vijai Singh
Publsiher: Springer Nature
Total Pages: 349
Release: 2020-04-13
ISBN 10: 9811500819
ISBN 13: 9789811500817
Language: EN, FR, DE, ES & NL

Advances in Synthetic Biology Book Review:

This book addresses the design of emerging conceptual tools, technologies and systems including novel synthetic parts, devices, circuits, oscillators, biological gates, and small regulatory RNAs (riboregulators and riboswitches), which serve as versatile control elements for regulating gene expression. Synthetic biology, a rapidly growing field that involves the application of engineering principles in biology, is now being used to develop novel systems for a wide range of applications including diagnostics, cell reprogramming, therapeutics, enzymes, vaccines, biomaterials, biofuels, fine chemicals and many more. The book subsequently summarizes recent developments in technologies for assembling synthetic genomes, minimal genomes, synthetic biology toolboxes, CRISPR-Cas systems, cell-free protein synthesis systems and microfluidics. Accordingly, it offers a valuable resource not only for beginners in synthetic biology, but also for researchers, students, scientists, clinicians, stakeholders and policymakers interested in the potential held by synthetic biology.

Synthetic Biology

Synthetic Biology
Author: Anton Glieder,Christian P. Kubicek,Diethard Mattanovich,Birgit Wiltschi,Michael Sauer
Publsiher: Springer
Total Pages: 368
Release: 2015-11-03
ISBN 10: 3319227084
ISBN 13: 9783319227085
Language: EN, FR, DE, ES & NL

Synthetic Biology Book Review:

This book provides a comprehensive, up-to-date overview of the opportunities and challenges of the complex field of synthetic biology, which combines various scientific disciplines. The emerging field of synthetic biology employs biotechnological approaches to recreate and enhance basic biological structures, intracellular processes and whole organisms. The book addresses a broad range of topics, including redesigning complex metabolic pathways, DNA/RNA and protein engineering, as well as novel synthetic biomaterials. It discusses both “bottom up” and “top down” approaches and presents the latest genome engineering tools with predictions about how these could change our way of thinking and working. Since the use of synthetic biology raises a number of ethical questions, a chapter is devoted to public awareness and risk management.The book is of interest to scientists from both academia and industry, as well as PhD students and postdocs working in the field

Biodefense in the Age of Synthetic Biology

Biodefense in the Age of Synthetic Biology
Author: National Academies of Sciences, Engineering, and Medicine,Division on Earth and Life Studies,Board on Life Sciences,Board on Chemical Sciences and Technology,Committee on Strategies for Identifying and Addressing Potential Biodefense Vulnerabilities Posed by Synthetic Biology
Publsiher: National Academies Press
Total Pages: 188
Release: 2019-01-05
ISBN 10: 0309465184
ISBN 13: 9780309465182
Language: EN, FR, DE, ES & NL

Biodefense in the Age of Synthetic Biology Book Review:

Scientific advances over the past several decades have accelerated the ability to engineer existing organisms and to potentially create novel ones not found in nature. Synthetic biology, which collectively refers to concepts, approaches, and tools that enable the modification or creation of biological organisms, is being pursued overwhelmingly for beneficial purposes ranging from reducing the burden of disease to improving agricultural yields to remediating pollution. Although the contributions synthetic biology can make in these and other areas hold great promise, it is also possible to imagine malicious uses that could threaten U.S. citizens and military personnel. Making informed decisions about how to address such concerns requires a realistic assessment of the capabilities that could be misused. Biodefense in the Age of Synthetic Biology explores and envisions potential misuses of synthetic biology. This report develops a framework to guide an assessment of the security concerns related to advances in synthetic biology, assesses the levels of concern warranted for such advances, and identifies options that could help mitigate those concerns.

BioBuilder

BioBuilder
Author: Natalie Kuldell PhD.,Rachel Bernstein,Karen Ingram,Kathryn M Hart
Publsiher: "O'Reilly Media, Inc."
Total Pages: 238
Release: 2015-06-22
ISBN 10: 1491907541
ISBN 13: 9781491907542
Language: EN, FR, DE, ES & NL

BioBuilder Book Review:

Today’s synthetic biologists are in the early stages of engineering living cells to help treat diseases, sense toxic compounds in the environment, and produce valuable drugs. With this manual, you can be part of it. Based on the BioBuilder curriculum, this valuable book provides open-access, modular, hands-on lessons in synthetic biology for secondary and post-secondary classrooms and laboratories. It also serves as an introduction to the field for science and engineering enthusiasts. Developed at MIT in collaboration with award-winning high school teachers, BioBuilder teaches the foundational ideas of the emerging synthetic biology field, as well as key aspects of biological engineering that researchers are exploring in labs throughout the world. These lessons will empower teachers and students to explore and be part of solving persistent real-world challenges. Learn the fundamentals of biodesign and DNA engineering Explore important ethical issues raised by examples of synthetic biology Investigate the BioBuilder labs that probe the design-build-test cycle Test synthetic living systems designed and built by engineers Measure several variants of an enzyme-generating genetic circuit Model "bacterial photography" that changes a strain’s light sensitivity Build living systems to produce purple or green pigment Optimize baker’s yeast to produce ?-carotene

Chemical Synthetic Biology

Chemical Synthetic Biology
Author: Pier Luigi Luisi,Cristiano Chiarabelli
Publsiher: John Wiley & Sons
Total Pages: 392
Release: 2011-02-10
ISBN 10: 9781119990307
ISBN 13: 1119990300
Language: EN, FR, DE, ES & NL

Chemical Synthetic Biology Book Review:

Chemistry plays a very important role in the emerging field of synthetic biology. In particular, chemical synthetic biology is concerned with the synthesis of chemical structures, such as proteins, that do not exist in nature. With contributions from leading international experts, Chemical Synthetic Biology shows how chemistry underpins synthetic biology. The book is an essential guide to this fascinating new field, and will find a place on the bookshelves of researchers and students working in synthetic chemistry, synthetic and molecular biology, bioengineering, systems biology, computational genomics, and bioinformatics.

Enzymes in Synthetic Biology

Enzymes in Synthetic Biology
Author: Anonim
Publsiher: Academic Press
Total Pages: 457
Release: 2018-08-30
ISBN 10: 0128151498
ISBN 13: 9780128151495
Language: EN, FR, DE, ES & NL

Enzymes in Synthetic Biology Book Review:

Volume 608 of the series Methods in Enzymology covers key aspects of enzyme discovery, engineering tools and platforms, and examples of applications in the enzymology of synthetic biology. Detailed methods for laboratory use of enzymes in synthetic biology applications Informative case history examples illustrating how enzyme and metabolic engineering are used to generate new products Emphasises latest developments in laboratory automation for the engineering of biology Covers many aspects of the design, build, test, learn cycle used in synthetic biology

Synthetic Biology

Synthetic Biology
Author: Bernd Giese,Christian Pade,Henning Wigger,Arnim von Gleich
Publsiher: Springer
Total Pages: 273
Release: 2014-09-27
ISBN 10: 3319027832
ISBN 13: 9783319027838
Language: EN, FR, DE, ES & NL

Synthetic Biology Book Review:

Synthetic Biology is already an object of intensive debate. However, to a great extent the discussion to date has been concerned with fundamental ethical, religious and philosophical questions. By contrast, based on an investigation of the field’s scientific and technological character, this book focuses on new functionalities provided by synthetic biology and explores the associated opportunities and risks. Following an introduction to the subject and a discussion of the most central paradigms and methodologies, the book provides an overview of the structure of this field of science and technology. It informs the reader about the current stage of development, as well as topical problems and potential opportunities in important fields of application. But not only the science itself is in focus. In order to investigate its broader impact, ecological as well as ethical implications will be considered, paving the way for a discussion of responsibilities in the context of a field at a transitional crossroads between basic and applied science. In closing, the requirements for a suitable regulatory framework are discussed. The book is intended as a source of information and orientation for researchers, students and practitioners in the natural sciences and technology assessment; for members of scientific and technological, governmental and funding institutions; and for members of the general public interested in essential information on the current status, prospects and implications of synthetic biology.

Regenesis

Regenesis
Author: George M. Church,Ed Regis
Publsiher: Basic Books
Total Pages: 304
Release: 2014-04-08
ISBN 10: 0465038654
ISBN 13: 9780465038657
Language: EN, FR, DE, ES & NL

Regenesis Book Review:

“Bold and provocative… Regenesis tells of recent advances that may soon yield endless supplies of renewable energy, increased longevity and the return of long-extinct species.”—New Scientist In Regenesis, Harvard biologist George Church and science writer Ed Regis explore the possibilities—and perils—of the emerging field of synthetic biology. Synthetic biology, in which living organisms are selectively altered by modifying substantial portions of their genomes, allows for the creation of entirely new species of organisms. These technologies—far from the out-of-control nightmare depicted in science fiction—have the power to improve human and animal health, increase our intelligence, enhance our memory, and even extend our life span. A breathtaking look at the potential of this world-changing technology, Regenesis is nothing less than a guide to the future of life.

Synthetic Biology and Morality

Synthetic Biology and Morality
Author: Gregory E. Kaebnick,Thomas H. Murray
Publsiher: MIT Press
Total Pages: 214
Release: 2013-07-26
ISBN 10: 0262519593
ISBN 13: 9780262519595
Language: EN, FR, DE, ES & NL

Synthetic Biology and Morality Book Review:

A range of views on the morality of synthetic biology and its place in public policy and political discourse.

Regulation of Synthetic Biology

Regulation of Synthetic Biology
Author: Alison McLennan
Publsiher: Edward Elgar Publishing
Total Pages: 424
Release: 2018-04-27
ISBN 10: 178536944X
ISBN 13: 9781785369445
Language: EN, FR, DE, ES & NL

Regulation of Synthetic Biology Book Review:

This book explores the interplay between regulation and emerging technologies in the context of synthetic biology, a developing field that promises great benefits, and has already yielded fuels and medicines made with designer micro-organisms. For all its promise, however, it also poses various risks. Investigating the distinctiveness of synthetic biology and the regulatory issues that arise, Alison McLennan questions whether synthetic biology can be regulated within existing structures or whether new mechanisms are needed.

Synthetic Biology

Synthetic Biology
Author: Madan L. Nagpal,Oana-Maria Boldura,Cornel Balta,Shymaa Enany
Publsiher: BoD – Books on Demand
Total Pages: 206
Release: 2020-02-12
ISBN 10: 1789840899
ISBN 13: 9781789840896
Language: EN, FR, DE, ES & NL

Synthetic Biology Book Review:

Synthetic biology gives us a new hope because it combines various disciplines, such as genetics, chemistry, biology, molecular sciences, and other disciplines, and gives rise to a novel interdisciplinary science. We can foresee the creation of the new world of vegetation, animals, and humans with the interdisciplinary system of biological sciences. These articles are contributed by renowned experts in their fields. The field of synthetic biology is growing exponentially and opening up new avenues in multidisciplinary approaches by bringing together theoretical and applied aspects of science.

Synthetic Biology

Synthetic Biology
Author: A. Balmer,K. Bulpin,S. Molyneux-Hodgson
Publsiher: Springer
Total Pages: 207
Release: 2016-06-01
ISBN 10: 1137495421
ISBN 13: 9781137495426
Language: EN, FR, DE, ES & NL

Synthetic Biology Book Review:

This book explores the emergence of a new scientific field, synthetic biology, and the many bold promises its proponents have made to change the future of science, industry, humanity and the global environment. It explores how people, including academics, students, industrialists and governance actors, tried to change their practices to bring engineering and biology together, and to realise such promises from within their everyday lives. It focuses on an ethnographic case study of an academic project that aimed to demonstrate the field's promise for solving water industry problems, from leaky pipes to climate change. In doing so, the book weaves together stories of barriers, bacteria and bodies, examining how they were entangled as people tried to make connections between academia and industry. It also reflects on the authors' attempts to work collaboratively with natural scientists and engineers, reflecting on current debates about the role of sociology in such interdisciplinary projects. The book contributes to contemporary studies of science and technology by highlighting issues such as ontology, practices, failure and time.