Stem Cells and the Future of Regenerative Medicine

Stem Cells and the Future of Regenerative Medicine
Author: Institute of Medicine,Board on Neuroscience and Behavioral Health,National Research Council,Division on Earth and Life Studies,Board on Life Sciences,Committee on the Biological and Biomedical Applications of Stem Cell Research
Publsiher: National Academies Press
Total Pages: 112
Release: 2002-01-25
ISBN 10: 9780309170420
ISBN 13: 0309170427
Language: EN, FR, DE, ES & NL

Stem Cells and the Future of Regenerative Medicine Book Review:

Recent scientific breakthroughs, celebrity patient advocates, and conflicting religious beliefs have come together to bring the state of stem cell researchâ€"specifically embryonic stem cell researchâ€"into the political crosshairs. President Bush’s watershed policy statement allows federal funding for embryonic stem cell research but only on a limited number of stem cell lines. Millions of Americans could be affected by the continuing political debate among policymakers and the public. Stem Cells and the Future of Regenerative Medicine provides a deeper exploration of the biological, ethical, and funding questions prompted by the therapeutic potential of undifferentiated human cells. In terms accessible to lay readers, the book summarizes what we know about adult and embryonic stem cells and discusses how to go about the transition from mouse studies to research that has therapeutic implications for people. Perhaps most important, Stem Cells and the Future of Regenerative Medicine also provides an overview of the moral and ethical problems that arise from the use of embryonic stem cells. This timely book compares the impact of public and private research funding and discusses approaches to appropriate research oversight. Based on the insights of leading scientists, ethicists, and other authorities, the book offers authoritative recommendations regarding the use of existing stem cell lines versus new lines in research, the important role of the federal government in this field of research, and other fundamental issues.

Stem Cells

Stem Cells
Author: Christine Mummery,Anja van de Stolpe,Bernard Roelen,Hans Clevers
Publsiher: Academic Press
Total Pages: 448
Release: 2014-05-23
ISBN 10: 0124115675
ISBN 13: 9780124115675
Language: EN, FR, DE, ES & NL

Stem Cells Book Review:

The second edition of Stem Cells: Scientific Facts and Fiction provides the non-stem cell expert with an understandable review of the history, current state of affairs, and facts and fiction of the promises of stem cells. Building on success of its award-winning preceding edition, the second edition features new chapters on embryonic and iPS cells and stem cells in veterinary science and medicine. It contains major revisions on cancer stem cells to include new culture models, additional interviews with leaders in progenitor cells, engineered eye tissue, and xeno organs from stem cells, as well as new information on "organs on chips" and adult progenitor cells. In the past decades our understanding of stem cell biology has increased tremendously. Many types of stem cells have been discovered in tissues that everyone presumed were unable to regenerate in adults, the heart and the brain in particular. There is vast interest in stem cells from biologists and clinicians who see the potential for regenerative medicine and future treatments for chronic diseases like Parkinson's, diabetes, and spinal cord lesions, based on the use of stem cells; and from entrepreneurs in biotechnology who expect new commercial applications ranging from drug discovery to transplantation therapies. Explains in straightforward, non-specialist language the basic biology of stem cells and their applications in modern medicine and future therapy Includes extensive coverage of adult and embryonic stem cells both historically and in contemporary practice Richly illustrated to assist in understanding how research is done and the current hurdles to clinical practice

Stem Cells Heterogeneity in Different Organs

Stem Cells Heterogeneity in Different Organs
Author: Alexander Birbrair
Publsiher: Springer Nature
Total Pages: 266
Release: 2019-09-05
ISBN 10: 3030241084
ISBN 13: 9783030241087
Language: EN, FR, DE, ES & NL

Stem Cells Heterogeneity in Different Organs Book Review:

This book presents a comprehensive discussion on the heterogeneity existing between different types of stem cells within the same tissue. As the functions of these stem cells vary, this is very important for the application of stem cells in cell therapy. This book describes the many recent developments that have revealed completely different roles of distinct stem cells within the same organ. Stem Cells Heterogeneity in Different Organs provides a timely update on the current information on stem cells heterogeneity in various tissues. It also provides a solid foundation of the history of stem cells from specific tissues and the current applications of this knowledge in regenerative medicine. Taken with its companion volumes, Stem Cells Heterogeneity: Novel Concepts and Stem Cells Heterogeneity in Cancer, this book is essential reading for advanced cell biology students as well as researchers and clinicians working with stem cells.

Stem Cells and Biomaterials for Regenerative Medicine

Stem Cells and Biomaterials for Regenerative Medicine
Author: Marek J. Los,Andrzej Hudecki,Emilia Wiechec
Publsiher: Academic Press
Total Pages: 249
Release: 2018-11-07
ISBN 10: 0128122781
ISBN 13: 9780128122785
Language: EN, FR, DE, ES & NL

Stem Cells and Biomaterials for Regenerative Medicine Book Review:

Stem Cells and Biomaterials for Regenerative Medicine addresses the urgent need for a compact source of information on both the cellular and biomaterial aspects of regenerative medicine. By developing a mutual understanding between three separately functioning areas of science—medicine, the latest technology, and clinical economics—the volume encourages interdisciplinary relationships that will lead to solutions for the significant challenges faced by today's regenerative medicine. Users will find sections on the homeostatic balance created by apoptosis and proliferating tissue stem cells, the naturally regenerative capacities of various tissue types, the potential regenerative benefits of iPS-generation, various differentiation protocols, and more. Written in easily accessbile language, this volume is appropriate for any professional or medical staff looking to expand their knowledge with regard to stem cells and regenerative medicine. Arms readers with key information on tissue engineering, artificial organs and biomaterials, while using broadly accessible language Provides broad introduction to, and examples of, various types of stem cells, core concepts of regenerative medicine, biomaterials, nanotechnology and nanomaterials, somatic cell transdyferentiation, and more Edited and authored by researchers with expertise in regenerative medicine, (cancer) stem cells, biomaterials, genetics and nanomaterials

Pluripotent Stem Cells

Pluripotent Stem Cells
Author: Deepa Bhartiya,Nibedita Lenka
Publsiher: BoD – Books on Demand
Total Pages: 640
Release: 2013-08-28
ISBN 10: 9535111922
ISBN 13: 9789535111924
Language: EN, FR, DE, ES & NL

Pluripotent Stem Cells Book Review:

Stem cells have generated a lot of excitement among the researchers, clinicians and the public alike. Various types of stem cells are being evaluated for their regenerative potential. Marginal benefit resulting by transplanting autologus stem cells (deemed to be absolutely safe) in various clinical conditions has been proposed to be a growth factor effect rather than true regeneration. In contrast, various pre-clinical studies have been undertaken, using differentiated cells from embryonic stem cells or induced pluripotent stem cells have shown promise, functional improvement and no signs of teratoma formation. The scientists are not in a rush to reach the clinic but a handful of clinical studies have shown promise. This book is a collection of studies/reviews, beginning with an introduction to the pluripotent stem cells and covering various aspects like derivation, differentiation, ethics, etc., and hence would provide insight into the recent standing on the pluripotent stem cells biology. The chapters have been categorized into three sections, covering subjects ranging from the generation of pluripotent stem cells and various means of their derivation from embryonic as well as adult tissues, the mechanistic understanding of pluripotency and narrating the potential therapeutic implications of these in vitro generated cells in various diseases, in addition to the associated pros and cons in the same.

Stem Cells Heterogeneity Novel Concepts

Stem Cells Heterogeneity   Novel Concepts
Author: Alexander Birbrair
Publsiher: Springer
Total Pages: 225
Release: 2019-04-23
ISBN 10: 3030110966
ISBN 13: 9783030110963
Language: EN, FR, DE, ES & NL

Stem Cells Heterogeneity Novel Concepts Book Review:

This book presents a comprehensive discussion on the novel concepts in stem cell heterogeneity, from pluripotent stem cells to human mesenchymal stem cells, adult and cancer stem cells of the thyroid, sarcoma, and more. Thus, Stem Cell Heterogeneity - Novel Concepts starts from a timely update on the current information on stem cells heterogeneity in various tissues and discusses new concepts and future directions. It also provides a solid foundation of the history of stem cells from specific tissues and the current applications of this knowledge in regenerative medicine. When taken as a whole, alongside its companion volumes Stem Cells Heterogeneity in Different Organs, and Stem Cells Heterogeneity in Cancer, these three books present a comprehensive reference on stem cell heterogeneity in various tissues and current and future applications for regenerative medicine. It is essential reading for advanced cell biology students as well as researchers in stem cells and clinicians.

Organoids and Mini Organs

Organoids and Mini Organs
Author: Jamie Davies,Melanie Lawrence
Publsiher: Academic Press
Total Pages: 284
Release: 2018-03-09
ISBN 10: 012812637X
ISBN 13: 9780128126370
Language: EN, FR, DE, ES & NL

Organoids and Mini Organs Book Review:

Organs and Organoids combines contributions from leading practitioners who work under the editorial control of an acclaimed researcher who also served for eight years as Editor-in-Chief of the journal Organogenesis, the first journal on this topic. The book begins with an introduction, but then delves into chapters that present advice on how to make organoids for many systems. In addition, case studies that illustrate the uses of organioids are presented, along with discussions on future directions and specific problems that need to be solved. Collects the best protocols of organoid cultures from diverse tissues Covers a wide range of organs Includes troubleshooting cases for common, but specific problems for each culture conditions Provides an entire section on the application of organoids

Tissue and Organ Regeneration

Tissue and Organ Regeneration
Author: Lijie Grace Zhang,Ali Khademhosseini,Thomas Webster
Publsiher: CRC Press
Total Pages: 822
Release: 2014-05-15
ISBN 10: 9814411671
ISBN 13: 9789814411677
Language: EN, FR, DE, ES & NL

Tissue and Organ Regeneration Book Review:

Tissue engineering aims to develop biological substitutes that restore, maintain, or improve damaged tissue and organ functionality. To date, numerous stem cells and biomaterials have been explored for a variety of tissue and organ regeneration. The challenge for existing stem cell–based techniques is that current therapies lack controlled environments that are crucial for regulating stem cell engraftment and differentiation in vivo, because stem cells are rather sensitive to even minute changes in their environment. Micro- and nanotechnology hold great potential to fabricate biomimetic spatiotemporally controlled scaffolds as well as control stem cell behavior and fate by micro- and nanoscale cues. This book presents the latest micro- and nanotechnologies used to manipulate stem cell behaviors, which is a critical area for regenerative medicine. Moreover, it covers and details cutting-edge research in nano- and microfabrication techniques and biomaterials for the regeneration of various tissues and organs, such as bone, cartilage, craniofacial, osteochondral, muscle, bladder, cardiac, and vascular tissues.

Stem Cell Therapy for Organ Failure

Stem Cell Therapy for Organ Failure
Author: Indumathi Somasundaram
Publsiher: Springer
Total Pages: 278
Release: 2015-01-02
ISBN 10: 8132221109
ISBN 13: 9788132221104
Language: EN, FR, DE, ES & NL

Stem Cell Therapy for Organ Failure Book Review:

The book “STEM CELL THERAPY FOR ORGAN FAILURES” edited by Dr. S. Indumathi demonstrates the In Vitro and In vivo therapeutic strategies and applications of pre- and post-natal stem cells for treating the failures of various organ systems of our body in a wide perspective. It explores the past, present and the futuristic approach of the exciting field of stem cells and its intriguing properties involved in tissue repair and regeneration. The prime focus of this volume is to unravel the basic, advanced, therapeutic and translational approaches put-forth so far in the field of stem cells and regenerative medicine at research, pre-clinical and clinical levels. Stem cells has ushered in widespread interest and exciting possibilities for cell based therapies, albeit failures do prevail and small uncontrolled phase I/II studies are only signals generating, rather than definite proof of concept thereby limiting its applicability in curative therapeutics. Despite certain initiatives and meticulous untiring efforts, bringing this basic bench side research into advanced transitional bedside remained a challenge. Thus, this book embarked upon the expanding researches in these areas that seem decisive in improvising regenerative medical therapeutics, thereby leading to further path-breaking studies that cure all health challenges facing mankind. Overall, this book reveals the imperativeness of various stem cell sources and its utility in curative therapeutics.

Essentials of Stem Cell Biology

Essentials of Stem Cell Biology
Author: Robert Lanza,John Gearhart,Brigid Hogan,Douglas Melton,Roger Pedersen,E. Donnall Thomas,James A. Thomson,Ian Sir Wilmut
Publsiher: Academic Press
Total Pages: 680
Release: 2009-06-05
ISBN 10: 9780080884974
ISBN 13: 0080884970
Language: EN, FR, DE, ES & NL

Essentials of Stem Cell Biology Book Review:

First developed as an accessible abridgement of the successful Handbook of Stem Cells, Essentials of Stem Cell Biology serves the needs of the evolving population of scientists, researchers, practitioners and students that are embracing the latest advances in stem cells. Representing the combined effort of seven editors and more than 200 scholars and scientists whose pioneering work has defined our understanding of stem cells, this book combines the prerequisites for a general understanding of adult and embryonic stem cells with a presentation by the world's experts of the latest research information about specific organ systems. From basic biology/mechanisms, early development, ectoderm, mesoderm, endoderm, methods to application of stem cells to specific human diseases, regulation and ethics, and patient perspectives, no topic in the field of stem cells is left uncovered. Selected for inclusion in Doody's Core Titles 2013, an essential collection development tool for health sciences libraries Contributions by Nobel Laureates and leading international investigators Includes two entirely new chapters devoted exclusively to induced pluripotent stem (iPS) cells written by the scientists who made the breakthrough Edited by a world-renowned author and researcher to present a complete story of stem cells in research, in application, and as the subject of political debate Presented in full color with glossary, highlighted terms, and bibliographic entries replacing references

Regenerative Medicine Applications in Organ Transplantation

Regenerative Medicine Applications in Organ Transplantation
Author: Giuseppe Orlando
Publsiher: Academic Press
Total Pages: 1050
Release: 2013-10-11
ISBN 10: 012398520X
ISBN 13: 9780123985200
Language: EN, FR, DE, ES & NL

Regenerative Medicine Applications in Organ Transplantation Book Review:

Regenerative Medicine Applications in Organ Transplantation illustrates exactly how these two fields are coming together and can benefit one another. It discusses technologies being developed, methods being implemented, and which of these are the most promising. The text encompasses tissue engineering, biomaterial sciences, stem cell biology, and developmental biology, all from a transplant perspective. Organ systems considered include liver, renal, intestinal, pancreatic, and more. Leaders from both fields have contributed chapters, clearly illustrating that regenerative medicine and solid organ transplantation speak the same language and that both aim for similar medical outcomes. The overall theme of the book is to provide insight into the synergy between organ transplantation and regenerative medicine. Recent groundbreaking achievements in regenerative medicine have received unprecedented coverage by the media, fueling interest and enthusiasm in transplant clinicians and researchers. Regenerative medicine is changing the premise of solid organ transplantation, requiring transplantation investigators to become familiar with regenerative medicine investigations that can be extremely relevant to their work. Similarly, regenerative medicine investigators need to be aware of the needs of the transplant field to bring these two fields together for greater results. Bridges the gap between regenerative medicine and solid organ transplantation and highlights reasons for collaboration Explains the importance and future potential of regenerative medicine to the transplant community Illustrates to regenerative medicine investigators the needs of the transplant discipline to drive and guide investigations in the most promising directions

The Art and Politics of Science

The Art and Politics of Science
Author: Harold Varmus
Publsiher: W. W. Norton & Company
Total Pages: 256
Release: 2010-05-24
ISBN 10: 0393073564
ISBN 13: 9780393073560
Language: EN, FR, DE, ES & NL

The Art and Politics of Science Book Review:

A Nobel Prize–winning cancer biologist, leader of major scientific institutions, and scientific adviser to President Obama reflects on his remarkable career. A PhD candidate in English literature at Harvard University, Harold Varmus discovered he was drawn instead to medicine and eventually found himself at the forefront of cancer research at the University of California, San Francisco. In this “timely memoir of a remarkable career” (American Scientist), Varmus considers a life’s work that thus far includes not only the groundbreaking research that won him a Nobel Prize but also six years as the director of the National Institutes of Health; his current position as the president of the Memorial Sloan-Kettering Cancer Center; and his important, continuing work as scientific adviser to President Obama. From this truly unique perspective, Varmus shares his experiences from the trenches of politicized battlegrounds ranging from budget fights to stem cell research, global health to science publishing.

Stem Cells in Clinical Practice and Tissue Engineering

Stem Cells in Clinical Practice and Tissue Engineering
Author: Rakesh Sharma
Publsiher: BoD – Books on Demand
Total Pages: 352
Release: 2018-05-02
ISBN 10: 1789230101
ISBN 13: 9781789230109
Language: EN, FR, DE, ES & NL

Stem Cells in Clinical Practice and Tissue Engineering Book Review:

Stem Cells in Clinical Practice and Tissue Engineering is a concise book on applied methods of stem cell differentiation and optimization using tissue engineering methods. These methods offer immediate use in clinical regenerative medicine. The present volume will serve the purpose of applied stem cell differentiation optimization methods in clinical research projects, as well as be useful to relatively experienced stem cell scientists and clinicians who might wish to develop their stem cell clinical centers or research labs further. Chapters are arranged in the order of basic concepts of stem cell differentiation, clinical applications of pluripotent stem cells in skin, cardiac, bone, dental, obesity centers, followed by tissue engineering, new materials used, and overall evaluation with their permitted legal status.

Organ Regeneration Based on Developmental Biology

Organ Regeneration Based on Developmental Biology
Author: Takashi Tsuji
Publsiher: Springer
Total Pages: 257
Release: 2017-03-30
ISBN 10: 981103768X
ISBN 13: 9789811037689
Language: EN, FR, DE, ES & NL

Organ Regeneration Based on Developmental Biology Book Review:

This book reviews three-dimensional (3D) stem cell culture and proof of concept for organ regeneration. The chapters present studies based on developmental biology but not tissue engineering using bio-degradative scaffolds. The ultimate goal of regenerative therapy, the next generation of regenerative therapy, is to develop fully functioning bioengineered 3D organs that can replace lost or damaged organs following disease, injury, or aging. Next-generation regenerative therapy will consist of organ-replacement regenerative therapy, which aims to reproduce reciprocal epithelial and epithelial interactions and epithelial and mesenchymal interactions that occur during embryogenesis. The book then discusses the generation of several 3D functional organs and organoids such as brain, inner ear, tooth, hair, salivary glands, lacrimal glands, gastrointestinal organs, kidney, liver, and lung. This work will appeal to a wide readership such as medical scientists, developmental biologists, clinicians, and patients. The volume provides valuable information and ideas to form a next-generation field of science.

Tissue Regeneration

Tissue Regeneration
Author: Hussein Abdelhay Essayed Kaoud
Publsiher: BoD – Books on Demand
Total Pages: 206
Release: 2018-06-06
ISBN 10: 1789232600
ISBN 13: 9781789232608
Language: EN, FR, DE, ES & NL

Tissue Regeneration Book Review:

Tissue regeneration is a vast subject, with many different important aspects to consider. Regenerative medicine is a new branch of medicine that tries to change the course of chronic diseases and, in many cases, regenerates the organ systems that fail due to age, disease, damage, or genetic defects. The main purpose of this book is to point out the interest of some important topics of tissue regeneration and the progress in this field as well as the variety of different surgical fields and operations. This book includes 7 sections and 11 chapters that provide an overview of the essentials in tissue regeneration science and their potential applications in surgery. The authors of each chapter have given consolidated information on ground realities and attempted to provide a comprehensive knowledge of tissue engineering and regeneration. This book will be useful to researchers and students of biological and biomedical sciences (medical and veterinarian researchers).

Essentials of Stem Cell Biology

Essentials of Stem Cell Biology
Author: Robert Lanza,Anthony Atala
Publsiher: Academic Press
Total Pages: 712
Release: 2013-08-31
ISBN 10: 0124104274
ISBN 13: 9780124104273
Language: EN, FR, DE, ES & NL

Essentials of Stem Cell Biology Book Review:

First developed as an accessible abridgement of the successful Handbook of Stem Cells, Essentials of Stem Cell Biology serves the needs of the evolving population of scientists, researchers, practitioners, and students embracing the latest advances in stem cells. Representing the combined effort of 7 editors and more than 200 scholars and scientists whose pioneering work has defined our understanding of stem cells, this book combines the prerequisites for a general understanding of adult and embryonic stem cells with a presentation by the world's experts of the latest research information about specific organ systems. From basic biology/mechanisms, early development, ectoderm, mesoderm, endoderm, and methods to the application of stem cells to specific human diseases, regulation and ethics, and patient perspectives, no topic in the field of stem cells is left uncovered. Contributions by Nobel Laureates and leading international investigators Includes two entirely new chapters devoted exclusively to induced pluripotent stem (iPS) cells written by the scientists who made the breakthrough Edited by a world-renowned author and researcher to present a complete story of stem cells in research, in application, and as the subject of political debate Presented in full color with a glossary, highlighted terms, and bibliographic entries replacing references

Stem Cell Microenvironments and Beyond

Stem Cell Microenvironments and Beyond
Author: Alexander Birbrair
Publsiher: Springer
Total Pages: 270
Release: 2017-12-03
ISBN 10: 3319691945
ISBN 13: 9783319691947
Language: EN, FR, DE, ES & NL

Stem Cell Microenvironments and Beyond Book Review:

This book discusses the main stem cell niches under distinct pathophysiological conditions. The role of tissue microenvironments in stem cell regulation, as well as modern methodologies and new techniques for the identification and characterization of stem cell niches, are discussed by leading experts in the field. Chapters describe the major components of various stem cell microenvironments, such as cellular components, soluble factors, cell-cell interactions, extra-cellular matrix proteins, and physical forces. Stem Cell Microenvironments and Beyond is part of the highly successful Advances in Experimental Medicine and Biology series. It is essential reading for graduate students and researchers in the field of stem cells or cell biology as well as clinicians.

Adult Stem Cells

Adult Stem Cells
Author: Kursad Turksen
Publsiher: Springer Science & Business
Total Pages: 429
Release: 2014-04-16
ISBN 10: 1461495695
ISBN 13: 9781461495697
Language: EN, FR, DE, ES & NL

Adult Stem Cells Book Review:

Adult Stem Cells, second edition, takes a critical look at issues concerning the developmental or differentiation potential for a variety of tissue types and for specific adult stem cell types. Since the first edition appeared a decade ago, our understanding of adult stem cells, and more specifically tissue-specific adult stem cells, has advanced tremendously. And an increased interest in regenerative medicine and potential stem cell applications has driven a quest for better understanding of stem cell biology. In turn, this has spawned much activity on generation and utilization of more and better reagents to identify and isolate stem cells and stem cell-like subpopulations, and on assays elucidating their developmental or differentiation potential and functional integration with host tissues and organs. In this fully updated new edition, chapters cover topics ranging from signaling pathways maintaining stemness in hematopoietic cells to regeneration after injury and endocrine mechanisms underlying the stem cell theory of aging. Other chapters cover stem cells by organ or system including pituitary, cardiac, epithelial, teeth, lung, ovary, prostate, liver, and many more. Importantly, the authors of the chapters have not only summarized their successes, but have also summarized some of the difficulties that each particular field is still facing with respect to maximizing the utility of stem cells in clinical settings. Collectively, they impart both the excitement and challenges facing stem cell utilization for repair and regeneration making this book essential reading for those involved in stem cell research as well as those involved in clinical assays.

Principles of Regenerative Medicine

Principles of Regenerative Medicine
Author: Anthony Atala,Robert Lanza,James A. Thomson,Robert Nerem
Publsiher: Academic Press
Total Pages: 1202
Release: 2010-12-16
ISBN 10: 9780123814234
ISBN 13: 0123814235
Language: EN, FR, DE, ES & NL

Principles of Regenerative Medicine Book Review:

Virtually any disease that results from malfunctioning, damaged, or failing tissues may be potentially cured through regenerative medicine therapies, by either regenerating the damaged tissues in vivo, or by growing the tissues and organs in vitro and implanting them into the patient. Principles of Regenerative Medicine discusses the latest advances in technology and medicine for replacing tissues and organs damaged by disease and of developing therapies for previously untreatable conditions, such as diabetes, heart disease, liver disease, and renal failure. Key for all researchers and instituions in Stem Cell Biology, Bioengineering, and Developmental Biology The first of its kind to offer an advanced understanding of the latest technologies in regenerative medicine New discoveries from leading researchers on restoration of diseased tissues and organs

Tissue Engineering for Artificial Organs

Tissue Engineering for Artificial Organs
Author: Anwarul Hasan
Publsiher: John Wiley & Sons
Total Pages: 752
Release: 2017-04-24
ISBN 10: 3527338632
ISBN 13: 9783527338634
Language: EN, FR, DE, ES & NL

Tissue Engineering for Artificial Organs Book Review:

A comprehensive overview of the latest achievements, trends, and the current state of the art of this important and rapidly expanding field. Clearly and logically structured, the first part of the book explores the fundamentals of tissue engineering, providing a separate chapter on each of the basic topics, including biomaterials stem cells, biosensors and bioreactors. The second part then follows a more applied approach, discussing various applications of tissue engineering, such as the replacement or repairing of skins, cartilages, livers and blood vessels, to trachea, lungs and cardiac tissues, to musculoskeletal tissue engineering used for bones and ligaments as well as pancreas, kidney and neural tissue engineering for the brain. The book concludes with a look at future technological advances. An invaluable reading for entrants to the field in biomedical engineering as well as expert researchers and developers in industry.