Stem Cells and Cell Therapy

Stem Cells and Cell Therapy
Author: Mohamed Al-Rubeai,Mariam Naciri
Publsiher: Springer Science & Business Media
Total Pages: 189
Release: 2013-10-01
ISBN 10: 9400771967
ISBN 13: 9789400771963
Language: EN, FR, DE, ES & NL

Stem Cells and Cell Therapy Book Review:

With the discovery of stem cells capable of multiplying indefinitely in culture and differentiating into many other cell types in appropriate conditions, new hopes were born in repair and replacement of damaged cells and tissues. The features of stem cells may provide treatment for some incurable diseases with some therapies are already in clinics, particularly those from adult stem cells. Some treatments will require large number of cells and may also require multiple doses, generating a growing demand for generating and processing large numbers of cells to meet the need of clinical applications. With this in mind, our aim is to provide a book on the subject of stem cells and cell therapy for researchers and students of cell biotechnology, bioengineering and bioproduction. This book is exceptional as it teaches researchers stem cells and cell therapy in that it covers the concepts and backgrounds necessary so that readers get a good understanding of the production of stem cells. The book covers three topics: The basics of stem cells and cell therapy, the use of stem cells for the treatment of human diseases, and stem cell processing. It includes chapters on neural and vascular stem vascular stem cell therapy, expansion engineering of embryonic stem cells, stem cell based production of blood cells and separation technologies for stem cells and cell therapy products. It is an informed and informative presentation of what modern research, science and engineering have learned about stem cells and their production and therapies. Addressing both the medical and production issues, this book is an invaluable contribution to having an academic and industrial understanding with respect to R&D and manufacturing of clinical grade stem cells.

Stem Cell Therapy for Diabetes

Stem Cell Therapy for Diabetes
Author: Shimon Efrat
Publsiher: Springer Science & Business Media
Total Pages: 291
Release: 2009-12-01
ISBN 10: 9781607613664
ISBN 13: 1607613662
Language: EN, FR, DE, ES & NL

Stem Cell Therapy for Diabetes Book Review:

Stem Cell Therapy for Diabetes, one of the latest installments of the Stem Cell Biology and Regenerative Medicine series, reviews the three main approaches for generation of sufficient numbers of insulin-producing cells for restoration of an adequate beta-cell mass: beta-cell expansion, stem-cell differentiation, and nuclear reprogramming. Adeptly collecting the research of the leading scientists in the field, Stem Cell Therapy for Diabetes compares the merits of employing autologous versus banked allogeneic cell sources for generation of surrogate beta cells, and addresses tissue engineering and ways for cell protection from recurring autoimmunity and graft rejection. Stem Cell Therapy for Diabetes provides essential reading for those especially interested in tracking the progress in applying of one of the most exciting new developments in bio-medicine towards a cure for diabetes.

Mesenchymal Stem Cell Therapy

Mesenchymal Stem Cell Therapy
Author: Lucas G. Chase,Mohan C Vemuri
Publsiher: Springer Science & Business Media
Total Pages: 456
Release: 2012-12-12
ISBN 10: 1627032002
ISBN 13: 9781627032001
Language: EN, FR, DE, ES & NL

Mesenchymal Stem Cell Therapy Book Review:

Over the past decade, significant efforts have been made to develop stem cell-based therapies for difficult to treat diseases. Multipotent mesenchymal stromal cells, also referred to as mesenchymal stem cells (MSCs), appear to hold great promise in regards to a regenerative cell-based therapy for the treatment of these diseases. Currently, more than 200 clinical trials are underway worldwide exploring the use of MSCs for the treatment of a wide range of disorders including bone, cartilage and tendon damage, myocardial infarction, graft-versus-host disease, Crohn’s disease, diabetes, multiple sclerosis, critical limb ischemia and many others. MSCs were first identified by Friendenstein and colleagues as an adherent stromal cell population within the bone marrow with the ability to form clonogenic colonies in vitro. In regards to the basic biology associated with MSCs, there has been tremendous progress towards understanding this cell population’s phenotype and function from a range of tissue sources. Despite enormous progress and an overall increased understanding of MSCs at the molecular and cellular level, several critical questions remain to be answered in regards to the use of these cells in therapeutic applications. Clinically, both autologous and allogenic approaches for the transplantation of MSCs are being explored. Several of the processing steps needed for the clinical application of MSCs, including isolation from various tissues, scalable in vitro expansion, cell banking, dose preparation, quality control parameters, delivery methods and numerous others are being extensively studied. Despite a significant number of ongoing clinical trials, none of the current therapeutic approaches have, at this point, become a standard of care treatment. Although exceptionally promising, the clinical translation of MSC-based therapies is still a work in progress. The extensive number of ongoing clinical trials is expected to provide a clearer path forward for the realization and implementation of MSCs in regenerative medicine. Towards this end, reviews of current clinical trial results and discussions of relevant topics association with the clinical application of MSCs are compiled in this book from some of the leading researchers in this exciting and rapidly advancing field. Although not absolutely all-inclusive, we hope the chapters within this book can promote and enable a better understanding of the translation of MSCs from bench-to-bedside and inspire researchers to further explore this promising and quickly evolving field.

Stem Cells

Stem Cells
Author: Mariusz Z. Ratajczak
Publsiher: Springer Nature
Total Pages: 329
Release:
ISBN 10: 3030312062
ISBN 13: 9783030312060
Language: EN, FR, DE, ES & NL

Stem Cells Book Review:

Stem Cell Therapy

Stem Cell Therapy
Author: Erik V. Greer
Publsiher: Nova Publishers
Total Pages: 234
Release: 2006
ISBN 10: 9781594548482
ISBN 13: 159454848X
Language: EN, FR, DE, ES & NL

Stem Cell Therapy Book Review:

Among the many applications of stem cell research are nervous system diseases, diabetes, heart disease, auto-immune diseases as well as Parkinson's disease, end-stage kidney disease, liver failure, cancer, spinal cord injury, multiple sclerosis, Parkinson's disease, and Alzheimer's disease. Stem cells are self-renewing, unspecialised cells that can give rise to multiple types all of specialised cells of the body. Stem cell research also involves complex ethical and legal considerations since they involve adult, foetal tissue and embryonic sources. This new book brings together leading research from throughout the world in this frontier field.

Handbook of Cardiac Stem Cell Therapy

Handbook of Cardiac Stem Cell Therapy
Author: Ioannis Dimarakis
Publsiher: World Scientific
Total Pages: 285
Release: 2009
ISBN 10: 1848162561
ISBN 13: 9781848162563
Language: EN, FR, DE, ES & NL

Handbook of Cardiac Stem Cell Therapy Book Review:

This book is an impressive compilation of contributions on the hot topic of cardiac stem cell therapy from leading groups all over the world. In the assembly of chapters, a structured approach is adopted; starting from the clinician's perspective, all developments in both the experimental and clinical research areas are covered. This journey will take the reader from the bench-top to the bedside, with all chapters written by leading authorities in their respective fields, including data still in press with medical journals. So, beyond being excellent as an overall update for scientists in the field of cardiac stem cell therapy, this book will likely prove an indispensable tool for every budding scientist considering a research project within this field.

Stem Cell based Therapy for Neurodegenerative Diseases

Stem Cell based Therapy for Neurodegenerative Diseases
Author: Fabin Han,Pengzhe (Paul) Lu
Publsiher: Springer Nature
Total Pages: 145
Release: 2020-10-26
ISBN 10: 9811543704
ISBN 13: 9789811543708
Language: EN, FR, DE, ES & NL

Stem Cell based Therapy for Neurodegenerative Diseases Book Review:

This book reviews the state-of-the-art in stem-cell-based therapies for neurodegenerative diseases, and highlights advances in both animal models and clinical trials. It comprehensively discusses most neurodegenerative diseases, including such as Parkinson's, Alzheimer's and Huntington’s diseases, amyotrophic sclerosis, multiple sclerosis, muscular dystrophy and retinal degeneration, in which stem cells could potentially be used for therapy in the future. It also addresses the challenges and problems relating to the translation of stem-cell-based therapies into treatments. As such, the book will appeal to research scientists, physicians, graduate students, and medical professionals in the field of stem cells, neuroscience, neurology, neurorestoratology and major neurological disorders.

The Future of Brain Repair a Realist s Guide to Stem Cell Therapy

The Future of Brain Repair   a Realist s Guide to Stem Cell Therapy
Author: Jack Price
Publsiher: Mit Press
Total Pages: 288
Release: 2020
ISBN 10: 0262043750
ISBN 13: 9780262043755
Language: EN, FR, DE, ES & NL

The Future of Brain Repair a Realist s Guide to Stem Cell Therapy Book Review:

"The Ultimate Therapy addresses the question: will stem cells bring about new, effective therapies for brain disorders? Stem cell therapies are the subject of enormous hype. The International Society for Stem Cell Research notes the 'near magical hold' that stem cell therapies have over patients' imaginations. This is not healthy. The intention with this book is to try to introduce some realism into this discussion. Certainly, stem cell therapies have real therapeutic promise, but it is important that patients, doctors, ethicists, regulators, and the public at large understand their potential and their limitations. Stem cell therapies have failed in the past. We need to understand why, and learn for the future. The therapies offered by unlicensed clinics are not the same as those going forward into proper regulated trials. We all need to understand the difference, and why it matters. Regenerative medicine for the brain-were it to emerge-would be the ultimate therapy. Brain diseases are more than just killers. Parkinson's disease, Alzheimer's disease, and stroke steal our capacity for thought, emotion, and social interaction. They destroy human faculties to a far greater degree even than disorders such as cancer. Further, repairing brain tissue is the ultimate biomedical challenge. The human brain is the most complex structure in the known universe, a structure we still barely understand. To be able to rebuild it once damaged is surely the ultimate prize for biomedical science. It is also the ultimate ethical challenge. We can rebuild joints, reconstitute blood, and regenerate liver with barely a thought for ethical concerns. But the prospect for brain repair stirs atavistic fears. Will I be the same person with new brain cells in my head? Stem cells offer the prospect for bringing this ultimate therapy to life, in a way that could be envisaged for no other therapeutic vehicle. Repairing brain with stem cells: truly the Ultimate Therapy"--

Stem Cell Therapy A Rising Tide How Stem Cells Are Disrupting Medicine and Transforming Lives

Stem Cell Therapy  A Rising Tide  How Stem Cells Are Disrupting Medicine and Transforming Lives
Author: Neil H. Riordan
Publsiher: Neil H Riordan
Total Pages: 302
Release: 2017-06-20
ISBN 10: 9780999045305
ISBN 13: 099904530X
Language: EN, FR, DE, ES & NL

Stem Cell Therapy A Rising Tide How Stem Cells Are Disrupting Medicine and Transforming Lives Book Review:

Stem cells are the repair cells of your body. When there aren't enough of them, or they aren't working properly, chronic diseases can manifest and persist. From industry leaders, sport stars, and Hollywood icons to thousands of everyday, ordinary people, stem cell therapy has helped when standard medicine failed. Many of them had lost hope. These are their stories. Neil H Riordan, author of MSC: Clinical Evidence Leading Medicine's Next Frontier, the definitive textbook on clinical stem cell therapy, brings you an easy-to-read book about how and why stem cells work, and why they're the wave of the future.

The Stem Cell Cure

The Stem Cell Cure
Author: Gaurav K. Goswami, MD,Kerry Johnson MBA PhD
Publsiher: Humanix Books
Total Pages: 329
Release: 2020-03-31
ISBN 10: 1630061190
ISBN 13: 9781630061197
Language: EN, FR, DE, ES & NL

The Stem Cell Cure Book Review:

The 150+ year lifespan of our ancient ancestors can be achieved once again by harnessing the power of our own cells with The Stem Cell Cure! Renowned regenerative and restorative sports medicine doctor Gaurav Goswami, M.D. provides advanced minimally invasive, non-surgical treatments to help his patients get back to peak performance levels – no matter their age. Harnessing the transformative power of stem cells is central to his expertise. In fact, stem cell therapy is proven to be effective in the treatment of many common conditions from arthritis and back pain to Alzheimer’s, Parkinson’s, and cancer. This book is an accessible and informative introduction to the amazing powers of Stem Cell Therapy – the biggest revolution in medicine since the discovery of penicillin, and a wave of the future. Co-authored by bestselling author and popular keynote speaker Kerry Johnson MBA PhD, The Stem Cell Cure provides specific ways for readers to boost their health and vitality for a lifetime by recovering, regenerating, and repairing injuries and disease.

Affordable Clean Air Facility for Stem Cell Therapy in an Academic Setting

Affordable Clean Air Facility for  Stem  Cell Therapy in an Academic Setting
Author: Una Chen
Publsiher: Anonim
Total Pages: 329
Release: 2016
ISBN 10:
ISBN 13: OCLC:1154304591
Language: EN, FR, DE, ES & NL

Affordable Clean Air Facility for Stem Cell Therapy in an Academic Setting Book Review:

Together with her colleagues, the author has worked extensively on the differentiation potential of mouse embryonic stem cells (ESCs) to blood islands containing embryoid bodies (EBs) in culture. Such EBs contain hematopoietic stem- precursor cells (HSCs) committed to lymphoid, myeloid lineages and cells possessing Natural Killer (NK) cell marker. Further differentiation of such EBs to mature B-lymphoid cells can be demonstrated in a second stage of tissue culture, by co-culturing separated EBs with a mitogen, Lipopolysaccharide (LPS). The demonstration of differentiation of such cells to mature T- and B-lymphoid cells was performed in vivo, id est, by implanting EBs subcutaneously in nude mice. The differentiation of ESCs to EBs needed to be scaled up to obtain enough HSC-containing EBs for a second stage of differentiation, in vitro and in vivo. Selection of HSC-containing EBs must be performed manually under a microscope outside the tissue culture incubator. For research purposes, the cell culture medium contains antibiotics to inhibit the growth of bacteria. However for clinical application, the medium should be free of antibiotics. A conventional research laboratory environment is not sufficient for such an application. A GMP (Good Manufacturing Production) facility with clean air became necessary. Commercial clean air facilities used in the operation room and/or by industry were over budget. The attention of the author has shifted to developing an affordable GMP facility for clinical research in academia. These efforts were successful and the price for such a GMP facility is 10% of a comparable industrial model. After that experience, "a GMP facility for cell therapy on wheels" was further developed. This chapter will describe and share with academic colleagues our experience of constructing such affordable GMP facilities from scratch, starting with the purchase of high-efficiency particulate arrestance (HEPA) filters for the clean air facility.

Animal Models for Stem Cell Therapy

Animal Models for Stem Cell Therapy
Author: Bruno Christ,Jana Oerlecke,Peggy Stock
Publsiher: Humana Press
Total Pages: 392
Release: 2014-09-01
ISBN 10: 9781493914524
ISBN 13: 1493914529
Language: EN, FR, DE, ES & NL

Animal Models for Stem Cell Therapy Book Review:

In Animal Models for Stem Cell Therapy: Methods and Protocols, expert researchers in the field detail disease models of hepatic, cardiovascular, neurological diseases, connective and contractile tissue. Chapters focus on a wide range of diseases and application of different kinds of stem cells and reprogrammed tissue cells (iPS). Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols and key tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Animal Models for Stem Cell Therapy: Methods and Protocols, covers interest of basic scientists and clinicians to assess the biological as well as the therapeutic potential of stem cell therapy.

Alternative Pluripotent Stem Cell Therapies Enhancement Act S 2754 Congressional Hearing

Alternative Pluripotent Stem Cell Therapies Enhancement Act  S  2754   Congressional Hearing
Author: Anonim
Publsiher: DIANE Publishing
Total Pages: 329
Release:
ISBN 10: 9781422320150
ISBN 13: 1422320154
Language: EN, FR, DE, ES & NL

Alternative Pluripotent Stem Cell Therapies Enhancement Act S 2754 Congressional Hearing Book Review:

Biomaterials for Stem Cell Therapy

Biomaterials for Stem Cell Therapy
Author: Loredana De Bartolo,Augustinus Bader
Publsiher: CRC Press
Total Pages: 662
Release: 2013-01-28
ISBN 10: 1466576391
ISBN 13: 9781466576391
Language: EN, FR, DE, ES & NL

Biomaterials for Stem Cell Therapy Book Review:

Focused on stem cell applications, this book bridges the fields of biomaterials, offering new insights into constructing and regenerating tissues and organs. Its unique feature is linking diseases of the human body to current thinking on how to deal with them in the context of current concepts and technologies by means of an in-depth focus on biomaterials. The book assembles recent advances and covers a range of topics related to stem cell biology, biomaterials and technological approaches such as bioreactors written by top researchers in the field. Stem cells of both embryonic and adult origin are discussed with applications ranging, but not limited to, nerve regeneration, liver, pancreas, skin, trachea, cartilage and bone repair and cardiovascular therapy. Developments in the field reflecting the design and construction of the human body and its principal anatomy are discussed from a materials point of view. The book will be a valuable tool for biomaterial scientists, tissue engineers, clinicians as well as stem cell biologists involved in basic research and applications of adult and embryonic stem cells. It will also be a source of reference for students in biotechnology, biomedical engineering, biology, biochemistry, materials sciences, pharmaceuticals, and veterinary and human medicine.

Advances in Stem Cell Research

Advances in Stem Cell Research
Author: Hossein Baharvand,Nasser Aghdami
Publsiher: Springer Science & Business Media
Total Pages: 398
Release: 2012-05-26
ISBN 10: 1617799408
ISBN 13: 9781617799402
Language: EN, FR, DE, ES & NL

Advances in Stem Cell Research Book Review:

Advances in Stem Cell Research discusses recent advances in stem cell science, including therapeutic applications. This volume covers such topics as biomanufacturing iPS cells for therapeutic applications, techniques for controlling stem cell fate decisions, as well as current basic research in such areas as germ line stem cells, genomics and proteomics in stem cell research. It is a useful book for biology and clinical scientists, especially young investigators and stem cell biology students who are newly entering the world of stem cells research. The editors hope that the new knowledge and research outlined in this book will help contribute to new therapies for a wide variety of diseases that presently afflict humanity.

Regenerative Medicine and Stem Cell Therapy for the Eye

Regenerative Medicine and Stem Cell Therapy for the Eye
Author: Brian G. Ballios,Michael J. Young
Publsiher: Anonim
Total Pages: 212
Release: 2018
ISBN 10: 9783319980812
ISBN 13: 3319980815
Language: EN, FR, DE, ES & NL

Regenerative Medicine and Stem Cell Therapy for the Eye Book Review:

This book provides an overview of the types, sources, and applications of stem cells in regenerating various ocular tissues, with a perspective on both potential applications of stem cells and possible challenges. The scope of the chapters include both preclinical and clinical applications, including stem cell-derived therapies based on endogenous tissue repair; stem cell transplantation and cell replacement therapy; gene therapy; and in vitro disease modelling. Additionally, the volume presents applications in both anterior and posterior ocular disease, with a particular focus on diseases of the ocular surface, cornea, limbus, and retina, including inherited retinal dystrophies as well as acquired diseases, such as age-related macular degeneration. Regenerative Medicine and Stem Cell Therapy for the Eye is an ideal book for advanced researchers in stem cell and ocular biology as well as clinical ophthalmologists, and will be of interest to readers with backgrounds in developmental biology and bioengineering. This book also Skillfully reviews cutting-edge advances in stem cell biology as applied to regenerative medicine and ocular disease Provides expert viewpoints on key hurdles and challenges to successful implementation of stem cell-derived therapies in the clinical domain Offers a multi-disciplinary, broad understanding of cell-based therapies for ocular diseases by incorporating perspectives from biomedical scientists, physicians, and engineers Examines the connection between cell therapy and gene editing, in particular relation to ocular disease.

Cell Therapy

Cell Therapy
Author: George Morstyn,William Sheridan
Publsiher: Cambridge University Press
Total Pages: 617
Release: 1996-03-29
ISBN 10: 9780521473156
ISBN 13: 0521473152
Language: EN, FR, DE, ES & NL

Cell Therapy Book Review:

Examines the current state and future prospects of haematopoietic cell therapy, including gene therapy and immunotherapy.

Regenerative and Cell Therapy

Regenerative and Cell Therapy
Author: A. Keating,K. Dicke,N. Gorin,R. Weber,H. Graf
Publsiher: Springer Science & Business Media
Total Pages: 180
Release: 2004-10-08
ISBN 10: 9783540220930
ISBN 13: 3540220933
Language: EN, FR, DE, ES & NL

Regenerative and Cell Therapy Book Review:

This book gives an updated review of the state of the art in regenerative cell therapy in the fields of cardiology, hematology, pediatrics, neurology, orthopedics and infectious diseases. The book emphasizes clinical advances as proof of concept in cell therapy based on the revolutionizing observation that regeneration can occur throughout the body even in highly differentiated organs like the heart and the neuronal system. It provides examples of breakthroughs in the clinical implementation of adult stem cell therapy.

In Vitro Models for Stem Cell Therapy

In Vitro Models for Stem Cell Therapy
Author: Peggy Stock,Bruno Christ
Publsiher: Humana
Total Pages: 290
Release: 2021-02-21
ISBN 10: 9781071612248
ISBN 13: 1071612247
Language: EN, FR, DE, ES & NL

In Vitro Models for Stem Cell Therapy Book Review:

This volume looks at in vitro disease models representing the respiratory, hepatobiliary, osteochondral, nervous, dermal, ocular, immune system, and pathological biological processes like tumorigenesis for stem cell research. The chapters in this book cover a range of diseases and application of various stem cells such as adult stem cells and iPS. Chapters also discuss new methods to characterize and manipulate stem cells with the aim to better understand and improve their biological performance. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Cutting-edge and thorough, In Vitro Models for Stem Cell Therapy: Methods and Protocols is a valuable resource for researchers and scientists interested in learning more about this exciting field

Regenerative Medicine

Regenerative Medicine
Author: Fidelis E O
Publsiher: Anonim
Total Pages: 46
Release: 2020-02-14
ISBN 10:
ISBN 13: 9798613110216
Language: EN, FR, DE, ES & NL

Regenerative Medicine Book Review:

REGENERATIVE MEDICINE.STEM CELLS & THE STEM CELL THERAPY.Stem cells otherwise known as "power cells or regenerative cells", are cells (primary cells) defined as cells when under the right bodily condition or laboratory condition, these cells can/would split to form what is known as daughter cells (secondary cells). These stem cells possess the ability to become either self-renewing kind of stem cells or the specialized kind of stem cells. The term therapeutic cloning as it appeals to stem cell is a method that is used to produce adaptive and highly resistant to genetic defects stem cells that can survive on their own without been fertilized. For this process to be effective there must be a willful donor. This procedure entails the removal of the nucleus (which is the embryonic cell here) from an egg that is not yet fertilized. To generate the clone in question, the nucleus which was hitherto removed would now be injected into the unfertilized egg. After some time there will be fission or disintegration which in turn now leads to what is known as stem line.Chemotherapy is a serious minded way of rescinding the ever speedy growth of cancerous cells in the body with the help of a well-planned chemical drug treatment. This chemotherapy procedure isn't a kind of treatment whose positive effect would be felt almost immediately. The chemotherapy is widely embraced as a way of cancerous treatment because of its effectiveness in the reduction of the chances for there to be spread of the malignant cells. This chemotherapeutic treatment comes with its own side effects (fatigue, fever, hair loss, loss of appetite, nausea, vomiting, weight loss and so on) and it is dependent on the type of cancerous growth, the location of the malignant cells and the general well-being of the individual.This book will enlighten you on all you need to know about stem cells and regenerative medicine. Enjoy reading!