Biology and Engineering of Stem Cell Niches

Biology and Engineering of Stem Cell Niches
Author: Ajaykumar Vishwakarma,Jeffrey M Karp
Publsiher: Academic Press
Total Pages: 642
Release: 2017-03-22
ISBN 10: 0128027568
ISBN 13: 9780128027561
Language: EN, FR, DE, ES & NL

Biology and Engineering of Stem Cell Niches Book Review:

Biology and Engineering of Stem Cell Niches covers a wide spectrum of research and current knowledge on embryonic and adult stem cell niches, focusing on the understanding of stem cell niche molecules and signaling mechanisms, including cell-cell/cell-matrix interactions. The book comprehensively reviews factors regulating stem cell behavior and the corresponding approaches for understanding the subsequent effect of providing the proper matrix molecules, mechanical cues, and/or chemical cues. It encompasses a variety of tools and techniques for developing biomaterials-based methods to model synthetic stem cell niches in vivo, or to enhance and direct stem cell fate in vitro. A final section of the book discusses stem cell niche bioengineering strategies and current advances in each tissue type. Includes the importance of Cell-Cell and Cell Matrix Interactions in each specific tissue and system Authored and edited by authorities in this emerging and multidisciplinary field Includes valuable links to 5-10 minute YouTube© author videos that describe main points

Epidermal Stem Cell Niche

Epidermal Stem Cell Niche
Author: Mirna Perez-Moreno
Publsiher: Academic Press
Total Pages: 230
Release: 2019-08-09
ISBN 10: 0128184477
ISBN 13: 9780128184479
Language: EN, FR, DE, ES & NL

Epidermal Stem Cell Niche Book Review:

Advances in Stem Cells and Their Niches, Volume Three, comprises a compilation of the latest findings on our understanding of skin biology. It extends the current knowledge on skin stem cells and provides in-depth discussions on their unique settings, niches and properties. Chapters in this new release include The biophysical regulation of epidermal fate and function, Epidermal stem cell lineages, Hair shaft progenitors that create a niche for hair pigmentation, Dermal papilla cells control of hair follicle growth and pigmentation, Molecular mechanisms regulating the hair follicle niche, Dermal fibroblasts and their niches and interactions with epidermal stem cells. Contains chapters written by international leaders in skin biology Provides a unique compilation of the latest findings and technologies in basic and translational skin biology Expands current knowledge on the regulation of skin stem cells as isolated entities, focusing on how skin stem cells and lineages of stem cells function in a coordinated manner Provides illustrations and comprehensive analyses of each subject

The Stem Cell Niche during Ageing

The Stem Cell Niche during Ageing
Author: Susie Prof. Nilsson
Publsiher: Academic Press
Total Pages: 258
Release: 2020-08-22
ISBN 10: 0128220201
ISBN 13: 9780128220207
Language: EN, FR, DE, ES & NL

The Stem Cell Niche during Ageing Book Review:

Advances in Stem Cells and Their Niches addresses stem cells during development, homeostasis, and disease/injury of the respective organs, presenting new developments in the field, including new data on disease and clinical applications. Video content illustrates such areas as protocols, transplantation techniques, and work with mice. Explores not only reviews of research, but also shares methods, protocols, and transplantation techniques Contains video content to illustrate such areas as protocols, transplantation techniques, and work with mice Each volume concentrates on one organ, making this a unique publication

Adult Stem Cell Niches

Adult Stem Cell Niches
Author: Sabine Wislet
Publsiher: BoD – Books on Demand
Total Pages: 330
Release: 2014-08-01
ISBN 10: 9535117181
ISBN 13: 9789535117186
Language: EN, FR, DE, ES & NL

Adult Stem Cell Niches Book Review:

Tissue-specific stem cells have the capacity to self-renew and differentiate into several types of functional cells that replenish lost cells throughout an organism?s lifetime. Studies on stem cells from diverse systems have shown that stem cell function is controlled by extracellular cues from the niche and by intrinsic genetic programs within the stem cell. The objectives of this book would be to review the molecular mechanisms that mediate the balanced response of stem cells to the needs of the organisms. Likewise, niches have also been linked to pathologies, by imposing aberrant function on stem cells or other targets. Therefore, the second objective of this book would be to highligh the molecular dysregulation of niche biology leading to the disease. The third objective would be to review the therapeutical targets described within stem cell niches.

Hematopoietic Stem Cell Niche

Hematopoietic Stem Cell Niche
Author: Anonim
Publsiher: Elsevier
Total Pages: 186
Release: 2017-03-10
ISBN 10: 0128113766
ISBN 13: 9780128113769
Language: EN, FR, DE, ES & NL

Hematopoietic Stem Cell Niche Book Review:

Hematopoietic Stem Cell Niche focuses on an individual organ, looking at the stem cells in the organ itself (if they exist), their niches, and how to use them alongside relevant methods and protocols. This series addresses stem cells during development, homeostasis, and disease/injury of the respective organs, presenting new developments in the field, including new data on disease and clinical applications. Video content illustrates such areas as protocols, transplantation techniques, and work with mice. Explores not only reviews of research, but also shares methods, protocols, and transplantation techniques Contains video content to illustrate such areas as protocols, transplantation techniques, and work with mice Each volume concentrates on one organ, making this a unique publication

Tissue Specific Stem Cell Niche

Tissue Specific Stem Cell Niche
Author: Kursad Turksen
Publsiher: Anonim
Total Pages: 329
Release: 2015
ISBN 10: 9783319217062
ISBN 13: 3319217062
Language: EN, FR, DE, ES & NL

Tissue Specific Stem Cell Niche Book Review:

This timely volume explores tissue-derived stem cells, summarizing and evaluating the current body of knowledge. Sixteen chapters cover hematopoietic, osteoblast, skeletal, cardiac, pancreatic, epithelial, corneal, hepatic, renal, testicular, ovarian, fingernail, hair follicle and other stem cells- discussing their individual development, functions, and pathologies, as well as the commonalities and interdependence between niches. This installment of the popular Stem Cell Biology and Regenerative Medicine series delivers authoritative, international perspectives on this rapidly growing field. Tissue-Specific Stem Cell Niche is an ideal complementary volume to Biology of Stem Cell Niche and Adult Stem Cells, Second Edition and will be invaluable to clinicians and researchers working with stem cells as well as to postgraduate trainees who are studying them.

Adult Stem Cell Niches Stem Cells in the Female Reproductive System

Adult Stem Cell Niches   Stem Cells in the Female Reproductive System
Author: Mirjana Kessler
Publsiher: Anonim
Total Pages: 329
Release: 2014
ISBN 10:
ISBN 13: OCLC:1154181408
Language: EN, FR, DE, ES & NL

Adult Stem Cell Niches Stem Cells in the Female Reproductive System Book Review:

Adult Stem Cell Niches - Stem Cells in the Female Reproductive System.

Biology in Stem Cell Niche

Biology in Stem Cell Niche
Author: Kursad Turksen
Publsiher: Springer
Total Pages: 228
Release: 2015-10-15
ISBN 10: 331921702X
ISBN 13: 9783319217024
Language: EN, FR, DE, ES & NL

Biology in Stem Cell Niche Book Review:

This comprehensive volume explores functions, pathologies, and applications of stem cells in relation to the niches in which they develop. Ten chapters cover the subject in depth, from a historical perspective through signaling, hormonal control, quiescence, biomimetics, epigenetics, engineering strategies for emulating, tumorigenesis and more. The chapter authors represent a broad range of international expertise and perspectives. This installment of the popular Stem Cell Biology and Regenerative Medicine series delivers authoritative, international perspectives on this rapidly growing field. Biology of Stem Cell Niche is an ideal complementary volume to Tissue-Specific Stem Cell Niche and Adult Stem Cells, Second Edition and will be invaluable to clinicians and researchers working with stem cells as well as to postgraduate trainees who are studying them.

The Cancer Stem Cell Niche

The Cancer Stem Cell Niche
Author: Susie Nilsson
Publsiher: Academic Press
Total Pages: 300
Release: 2021-02-15
ISBN 10: 9780323853255
ISBN 13: 0323853250
Language: EN, FR, DE, ES & NL

The Cancer Stem Cell Niche Book Review:

Advances in Stem Cells and their Niches series, highlights new advances in the field, with this new volume presenting interesting chapters. Each chapter is written by an international board of authors. Provides the authority and expertise of leading contributors from an international board of authors Presents the latest release in the Advances in Stem Cells and their Niches series Updated release includes the latest information on the The Cancer Stem Cell Niche

Stem Cell Niche

Stem Cell Niche
Author: Kursad Turksen
Publsiher: Humana Press
Total Pages: 270
Release: 2013-08-29
ISBN 10: 9781627035071
ISBN 13: 1627035079
Language: EN, FR, DE, ES & NL

Stem Cell Niche Book Review:

Interest in a specialized microenvironment or “niche” regulating hemopoietic stem cell function has been steadily growing since the idea was first proposed by Ray Schofield over three decades ago. This growing interest, as well as more recently the interest in cellular-molecular-biochemical characterization of not only the hemopoietic stem cell niche but the niches for other stem cells, incited the compilation of Stem Cell Niche: Methods and Protocols. In this volume, scientists have provided protocols that will provide both a flavor of the field and hopefully stimulate new approaches and methodologies by those interested in the stem cell niche. Written in the successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols, and notes on troubleshooting and avoiding known pitfalls. Authoritative and easily accessible, Stem Cell Niche: Methods and Protocols seeks to serve both experts and novices in the stem cell field with well-established protocols on this exciting subject.

Biomaterials as Stem Cell Niche

Biomaterials as Stem Cell Niche
Author: Krishnendu Roy
Publsiher: Springer Science & Business Media
Total Pages: 309
Release: 2010-09-30
ISBN 10: 9783642138935
ISBN 13: 3642138934
Language: EN, FR, DE, ES & NL

Biomaterials as Stem Cell Niche Book Review:

Recent developments in stem cell biology have opened new directions in cell therapy. This book provides the state-of-the-art developments in using biomaterials as artificial niches for engineering stem cells, both for the purpose of better understanding their biology under 3D biomimetic conditions as well as for developing new strategies for efficient long term maintenance and directed differentiation of stem cells into various therapeutic lineages. Animal and human stem cells of both embryonic and adult origin are discussed with applications ranging from nerve regeneration, orthopedics, cardiovascular therapy, blood cell generation and cancer therapy. Both synthetic and natural biomaterials are reviewed with emphasis on how material-stem cell interactions direct specific signaling pathways and ultimately modulate the cell fate. This book is valuable for biomaterial scientists, tissue engineers, clinicians as well as stem cell biologists involved in basic research and applications of adult and embryonic stem cells.

The Modulatable Stem Cell Niche Tissue Interactions During Hair and Feather Follicle Regeneration

The Modulatable Stem Cell Niche  Tissue Interactions During Hair and Feather Follicle Regeneration
Author: Anonim
Publsiher: Anonim
Total Pages: 329
Release: 2016
ISBN 10:
ISBN 13: OCLC:1052052466
Language: EN, FR, DE, ES & NL

The Modulatable Stem Cell Niche Tissue Interactions During Hair and Feather Follicle Regeneration Book Review:

Abstract: Hair and feathers are unique because (1) their stem cells are contained within a follicle structure, (2) they undergo cyclic regeneration repetitively throughout life, (3) regeneration occurs physiologically in healthy individuals and (4) regeneration is also induced in response to injury. Precise control of this cyclic regeneration process is essential for maintaining the homeostasis of living organisms. While stem cells are regulated by the intra-follicle-adjacent micro-environmental niche, this niche is also modulated dynamically by extra-follicular macro-environmental signals, allowing stem cells to adapt to a larger changing environment and physiological needs. Here we review several examples of macro-environments that communicate with the follicles: intradermal adipose tissue, innate immune system, sex hormones, aging, circadian rhythm and seasonal rhythms. Related diseases are also discussed. Unveiling the mechanisms of how stem cell niches are modulated provides clues for regenerative medicine. Given that stem cells are hard to manipulate, focusing translational therapeutic applications at the environments appears to be a more practical approach. Graphical abstract: Highlights: Hair follicle stem cells are regulated by many extra-follicular sources. Signals from the adipose tissue modulate hair stem cell behavior and aging. Upon injury, innate immune response triggers regeneration through quorum sensing. The effects of androgen on hair growth are different in different regions and ages. Seasonal and circadian rhythms modulate the length of hair cycling.

Pluripotent Stem Cells

Pluripotent Stem Cells
Author: Minoru Tomizawa
Publsiher: BoD – Books on Demand
Total Pages: 532
Release: 2016-07-20
ISBN 10: 9535124714
ISBN 13: 9789535124719
Language: EN, FR, DE, ES & NL

Pluripotent Stem Cells Book Review:

Pluripotent stem cells have distinct characteristics: self-renewal and the potential to differentiate into various somatic cells. In recent years, substantial advances have been made from basic science to clinical applications. The vast amount knowledge available makes obtaining concise yet sufficient information difficult, hence the purpose of this book. In this book, embryonic stem cells, induced pluripotent stem cells, and mesenchymal stem cells are discussed. The book is divided into five sections: pluripotency, culture methods, toxicology, disease models, and regenerative medicine. The topics covered range from new concepts to current technologies. Readers are expected to gain useful information from expert contributors.

Stem Cell Microenvironments and Beyond

Stem Cell Microenvironments and Beyond
Author: Alexander Birbrair
Publsiher: Springer
Total Pages: 270
Release: 2017-12-03
ISBN 10: 3319691945
ISBN 13: 9783319691947
Language: EN, FR, DE, ES & NL

Stem Cell Microenvironments and Beyond Book Review:

This book discusses the main stem cell niches under distinct pathophysiological conditions. The role of tissue microenvironments in stem cell regulation, as well as modern methodologies and new techniques for the identification and characterization of stem cell niches, are discussed by leading experts in the field. Chapters describe the major components of various stem cell microenvironments, such as cellular components, soluble factors, cell-cell interactions, extra-cellular matrix proteins, and physical forces. Stem Cell Microenvironments and Beyond is part of the highly successful Advances in Experimental Medicine and Biology series. It is essential reading for graduate students and researchers in the field of stem cells or cell biology as well as clinicians.

The Cell Biology of Stem Cells

The Cell Biology of Stem Cells
Author: Eran Meshorer,Kathrin Plath
Publsiher: Springer Science & Business Media
Total Pages: 229
Release: 2011-01-11
ISBN 10: 9781441970374
ISBN 13: 1441970371
Language: EN, FR, DE, ES & NL

The Cell Biology of Stem Cells Book Review:

Stem cells have been gaining a lot of attention in recent years. Their unique potential to self-renew and differentiate has turned them into an attractive model for the study of basic biological questions such as cell division, replication, transcription, cell fate decisions, and more. With embryonic stem (ES) cells that can generate each cell type in the mammalian body and adult stem cells that are able to give rise to the cells within a given lineage, basic questions at different developmental stages can be addressed. Importantly, both adult and embryonic stem cells provide an excellent tool for cell therapy, making stem cell research ever more pertinent to regenerative medicine. As the title The Cell Biology of Stem Cells suggests, our book deals with multiple aspects of stem cell biology, ranging from their basic molecular characteristics to the in vivo stem cell trafficking of adult stem cells and the adult stem-cell niche, and ends with a visit to regeneration and cell fate reprogramming. In the first chapter, “Early embryonic cell fate decisions in the mouse”, Amy Ralson and Yojiro Yamanaka describe the mechanisms that support early developmental decisions in the mouse pre-implantation embryo and the current understanding of the source of the most immature stem cell types, which includes ES cells, trophoblast stem (TS) cells and extraembryonic endoderm stem (XEN) cells.

Glioma Stem Cell Niches in Human Glioblastoma Are Periarteriolar

Glioma Stem Cell Niches in Human Glioblastoma Are Periarteriolar
Author: Anonim
Publsiher: Anonim
Total Pages: 329
Release:
ISBN 10:
ISBN 13: OCLC:1051962293
Language: EN, FR, DE, ES & NL

Glioma Stem Cell Niches in Human Glioblastoma Are Periarteriolar Book Review:

Survival of primary brain tumor (glioblastoma) patients is seriously hampered by glioma stem cells (GSCs) that are distinct therapy-resistant self-replicating pluripotent cancer cells. GSCs reside in GSC niches, which are specific protective microenvironments in glioblastoma tumors. We have recently found that GSC niches are hypoxic periarteriolar, whereas in most studies, GSC niches are identified as hypoxic perivascular. The aim of this review is to critically evaluate the literature on perivascular GSC niches to establish whether these are periarteriolar, pericapillary, perivenular, and/or perilymphatic. We found six publications showing images of human glioblastoma tissue containing perivascular GSC niches without any specification of the vessel type. However, it is frequently assumed that these vessels are capillaries which are exchange vessels, whereas arterioles and venules are transport vessels. Closer inspection of the figures of these publications showed vessels that were not capillaries. Whether these vessels were arterioles or venules was difficult to determine in one case, but in the other cases, these were clearly arterioles and their perivascular niches were similar to the periarteriolar niches we have found. Therefore, we conclude that in human glioblastoma tumors, GSC niches are hypoxic periarteriolar and are structurally and functionally look-alikes of hematopoietic stem cell niches in the bone marrow.

Stem Cell Transplantation

Stem Cell Transplantation
Author: Carlos López-Larrea,Antonio López Vázquez,Beatriz Suárez Álvarez
Publsiher: Springer Science & Business Media
Total Pages: 342
Release: 2012-03-28
ISBN 10: 1461420989
ISBN 13: 9781461420989
Language: EN, FR, DE, ES & NL

Stem Cell Transplantation Book Review:

Organ transplantation has been the most important therapeutic advance in the last third of the 20th century. Its development has revolutionized medicine, as demonstrated by the fact that a large number of researchers in this field have been awarded Nobel Prizes. In the beginning of this century, we are witnessing with great expectations the emergence of a new field of medicine related to the arrival of a new player on the scene: “stem cells” and their potential use in regenerative medicine. This volume aims to cover important aspects of the various facets of organ transplantation and regenerative medicine, with leading specialists in these fields setting out their vision. We try to rigorously explain current and novel scientific research in these fields—areas which arouse great interest from society in general, due to their potential use in modern medicine for the treatment of a great number of diseases.

Hematopoletic Stem Cell Niches from Fetal Stages to Teh Aging Bone Marrow

Hematopoletic Stem Cell Niches from Fetal Stages to Teh Aging Bone Marrow
Author: Patrick Michael Helbling
Publsiher: Anonim
Total Pages: 329
Release: 2020
ISBN 10:
ISBN 13: OCLC:1183706970
Language: EN, FR, DE, ES & NL

Hematopoletic Stem Cell Niches from Fetal Stages to Teh Aging Bone Marrow Book Review:

Neural Stem Cells and Adult Neurogenesis

Neural Stem Cells and Adult Neurogenesis
Author: Arie S. Mobley
Publsiher: Academic Press
Total Pages: 375
Release: 2019-03-15
ISBN 10: 0128110147
ISBN 13: 9780128110140
Language: EN, FR, DE, ES & NL

Neural Stem Cells and Adult Neurogenesis Book Review:

Neural Stem Cells and Adult Neurogenesis provides graduate students and neuroscientists with a basic understanding of what neural stem cells are and the cell types they produce. This early graduate level reference describes their physiology and potential for medicine and provides students with fundamental stem cell information. An overview of stem cell sources in the human body and a brief mention of relevant diseases provide context for the value of this knowledge. The book also includes chapters on induced pluripotent stem cells (iPSCs), the methods used to obtain them, and a review of the ethical challenges associated with stem cell research. For each region, the book provides a description of its neurogenic niche, cellular and molecular biology, and information on the neurons' contribution to normal and diseased brain function. The level of information is appropriate for early graduate students, introducing technology and molecular biology in an accessible format. Provides a basic understanding of what a stem cell is, the different types, and their potential in health and research Details adult neurogenesis and its role in behavior, stroke and disease Includes walkthrough and technology boxes that illustrate experimental concepts, new approaches and techniques

Stem Cell Aging Mechanisms Consequences Rejuvenation

Stem Cell Aging  Mechanisms  Consequences  Rejuvenation
Author: Hartmut Geiger,Heinrich Jasper,Maria Carolina Florian
Publsiher: Springer
Total Pages: 354
Release: 2015-07-06
ISBN 10: 370911232X
ISBN 13: 9783709112328
Language: EN, FR, DE, ES & NL

Stem Cell Aging Mechanisms Consequences Rejuvenation Book Review:

Aging of somatic stem cells reduces cell function and results in dysfunctional organs and tissues, making it an underlying cause of diseases associated with aging. It might even be the primary cause for age-associated attrition of tissue function in organs that heavily rely on stem cells for maintaining homeostasis, like the skin, blood and intestines. Understanding the molecular and cellular mechanisms involved is critical for developing approaches to attenuate stem cell aging and could pave the way for improved quality of life among the elderly. Written by highly prominent experts in the field, this book presents the current state of knowledge on these mechanisms. It offers insights into stem cell function, explains in detail the mechanisms of stem cell aging in model organisms as well as mammalian systems and describes related diseases and approaches to attenuating stem cell aging or achieving rejuvenation. The book is intended for all scientists and clinicians working with stem cells, aging mechanisms or age-related diseases.