Stem Cell Innovation in Health and Disease

Stem Cell Innovation in Health and Disease
Author: Ahmed H.K. El-Hashash
Publsiher: Academic Press
Total Pages: 200
Release: 2021-06-15
ISBN 10: 9780128212066
ISBN 13: 0128212063
Language: EN, FR, DE, ES & NL

Stem Cell Innovation in Health and Disease Book Review:

In the lung, more recent data have been accumulated on lung stem cell biology/function and the potential applications of stem cells in pulmonary diseases that are facilitated by the recent development of a broad range of cutting edge in vitro and in vivo research tools and approaches, including mouse and human organoid cultures, genetic editing in vitro and in vivo, human induced pluripotent cell (iPS cell) models of disease, haploid cells for genetic as well as compound screening paradigms, genetically engineered mice, and stem cell transplantation to cure diseases. Stem Cell Innovation in Health and Disease: Volume 2: The Lung, contains two major sections describing cutting edge research for understanding stem cell functions in the lung and respiratory system, and for developing methods to bring stem cells from bench to bedside; respectively. Each section includes insights ranging from using mouse and human organoid cultures, genetic editing in vitro and in vivo, and human induced pluripotent cells (iPSCs) to study stem cell functions and model lung diseases, through the cutting-edge research aiming to bring stem cells from bench to bedside, including the potential application of iPSCs, ESCs and blood stem cells (stem cell transplants) in the treatment of lung diseases/disorders. This book, therefore, discusses the fact-based promise of stem cells and regenerative medicine in the lung in the real world. Provides intensive scientific background and most recent information on cutting edge research to understand respiratory stem cell functions and develop methods to bring stem cells from bench to bedside for different lung diseases Analyzes the current state, opportunities, and challenges of innovative technologies and stem cells from bench to bed, including organoids and iPSC-derived alveolar epithelia cell therapy in the lung Contains two major sections describing cutting-edge research for understanding stem cell functions and for developing methods specific to the lung

Stem Cell Innovation in Health and Disease

Stem Cell Innovation in Health and Disease
Author: Eiman Abdel Meguid,Ahmed H.K. El-Hashash
Publsiher: Academic Press
Total Pages: 200
Release: 2021-06-15
ISBN 10: 9780128212691
ISBN 13: 0128212691
Language: EN, FR, DE, ES & NL

Stem Cell Innovation in Health and Disease Book Review:

The intestine is among the leading organs, in which several cutting edge in vitro and in vivo research tools and approaches have recently been developed and used to investigate stem cell biology/function, and the potential applications of stem cells in the treatment of intestinal diseases. These cutting-edge research tools and approaches involve human and murine organoid cultures, genetic editing in vitro and in vivo, human induced pluripotent cell (iPS cell) models of disease, haploid cells for genetic as well as compound screening paradigms, genetically engineered mice, and stem cell transplantation to cure diseases. Stem Cell Innovation in Health and Disease: Volume 1: The Intestine contains two major sections describing cutting edge research for understanding stem cell functions in the intestine, and for developing methods to bring stem cells from bench to bedside; respectively. Each section includes insights ranging from using mouse and human organoid cultures, genetic editing in vitro and in vivo, and human induced pluripotent cells (iPSCs) to study stem cell functions and model intestinal diseases, through the cutting-edge research, including the potential application of iPSCs, ESCs and blood stem cells (stem cell transplants) in the treatment of intestinal diseases/disorders. This volume, therefore, discusses the fact-based promise of stem cells and regenerative medicine in the intestine in the real world. Provides intensive scientific background and most recent information on cutting edge research to understand intestinal stem cell functions and develop methods to bring stem cells from bench to bedside for different intestinal diseases Analyzes the current state, opportunities, and challenges of innovative technologies and stem cells from bench to bed, including organoids and the CRISPR gene editing system in the intestine Contains two major sections describing cutting-edge research for understanding stem cell functions and for developing methods specific to the intestine

Developmental and Stem Cell Biology in Health and Disease

Developmental and Stem Cell Biology in Health and Disease
Author: Ahmed El-Hashash
Publsiher: Bentham Science Publishers
Total Pages: 260
Release: 2016-07-14
ISBN 10: 1681082195
ISBN 13: 9781681082196
Language: EN, FR, DE, ES & NL

Developmental and Stem Cell Biology in Health and Disease Book Review:

Research into stem cells started in the 1960s with experiments on spleen cultures. Evans and Kaufman made a breakthrough in mouse embryo culturing and embryonic stem cell extraction in 1981, followed by the work of Thomson in 1998 on the technique for extracting human embryonic stem cells. Since then, stem cell research has rapidly expanded as a therapeutic avenue for different diseases in humans. This book explains the basic developmental biology of stem cells including the development of stem cells during the implantation stage in utero to the regulation of stem cell division. Medical applications of stem cells in the therapy of diseases such as cancer, neurodegenerative diseases, and bone diseases are also explained in subsequent chapters. The book also explains the effect of parasitic cells on stem cell growth. Concepts in the book are explained in a simple clear manner, making this book an informative reference for non-experts, students and professionals in the field of biology and medicine.

Mesenchymal Stem Cells in Human Health and Diseases

Mesenchymal Stem Cells in Human Health and Diseases
Author: Ahmed H.K. El-Hashash
Publsiher: Academic Press
Total Pages: 228
Release: 2020-01-07
ISBN 10: 0128205334
ISBN 13: 9780128205334
Language: EN, FR, DE, ES & NL

Mesenchymal Stem Cells in Human Health and Diseases Book Review:

Mesenchymal Stem Cells in Human Health and Diseases provides a contemporary overview of the fast-moving field of MSC biology, regenerative medicine and therapeutics. MSCs offer the potential to dramatically reduce human suffering from disease. Numerous MSC-based studies are ongoing each year, each offering hope for novel treatments in human disease. This book provides information on MSC application in well-studied human diseases and tissue repair/regeneration and recent advances in their research and treatment. These discoveries are placed within the structural context of tissue and developmental biology in sections dealing with recent advances in our understanding of MSC biology. Includes insights ranging from MSC biology and development through the derivation and identification and properties of MSCs Helps to identify potential innovative solutions for restoring normal morphogenesis and/or regeneration of diseased organs Discusses the fact-based promise of MSC therapeutics and regenerative medicine in the real world

Stem Cell-Based Therapy for Lung Disease

Stem Cell-Based Therapy for Lung Disease
Author: Janette K. Burgess,Irene H. Heijink
Publsiher: Springer Nature
Total Pages: 259
Release: 2019-11-23
ISBN 10: 303029403X
ISBN 13: 9783030294038
Language: EN, FR, DE, ES & NL

Stem Cell-Based Therapy for Lung Disease Book Review:

This book presents state-of-the-art pre-clinical models and clinical applications of stem-cell-based therapies applied to different lung diseases, with a special focus on the translation of bench data into clinical studies. Starting with the assumption that abnormal lung tissue repair and regeneration has emerged as the driving force underlying pathogenesis and progression in many lung diseases, it sheds new light on the potential of stem/stromal cells as drivers of repair and sources of reparative factors in the lung. The first part of the book offers an overview of stem cell types and mechanisms involved in lung development, homeostasis, repair and regeneration, and reveals the crucial role of the extracellular matrix within the lung microenvironment. In the second part, leading experts present the latest pre-clinical evidence and clinical applications of stem-cell-based therapies in a wide variety of lung diseases, ranging from COPD and lung fibrosis to other rare lung diseases. The last section discusses stem cell delivery systems and devices, such as aerosolised spray application. This book appeals to pneumologists, stem cell and matrix biologists, as well as bioengeneers with a special interest in regenerative medicine applied to pulmonary diseases.

The SAGE Encyclopedia of Stem Cell Research

The SAGE Encyclopedia of Stem Cell Research
Author: Eric E. Bouhassira
Publsiher: SAGE Publications
Total Pages: 1552
Release: 2015-06-15
ISBN 10: 1483347672
ISBN 13: 9781483347677
Language: EN, FR, DE, ES & NL

The SAGE Encyclopedia of Stem Cell Research Book Review:

The SAGE Encyclopedia of Stem Cell Research, Second Edition is filled with new procedures and exciting medical breakthroughs, including executive orders from the Obama administration reversing barriers to research imposed under the Bush administration, court rulings impacting NIH funding of research based on human embryonic stem cells, edicts by the Papacy and other religious leaders, and the first success in cloning human stem cells. Stem cell biology is clearly fueling excitement and potential in traditional areas of developmental biology and in the field of regenerative medicine, where they are believed to hold much promise in addressing any number of intractable medical conditions. This updated second edition encyclopedia will expand on information that was given in the first edition and present more than 270 new and updated articles that explore major topics in ways accessible to nonscientists, thus bringing readers up-to-date with where stem cell biology stands today, including new and evolving ethical, religious, legal, social, and political perspectives. This second edition reference work will serve as a universal resource for all public and academic libraries. It is an excellent foundation for anyone who is interested in the subject area of stem cell biology. Key Features: Reader’s Guide, Further Readings, Cross References, Chronology, Resource Guide, Index A Glossary will elucidate stem cell terminology for the nonscientist Statistics and selected reprints of major journal articles that pertain to milestones achieved in stem cell research Documents from Congressional Hearings on stem cells and cloning Reports to the President’s Council on Bioethics, and more

Perinatal Stem Cells

Perinatal Stem Cells
Author: Anthony Atala,Sean V. Murphy
Publsiher: Springer
Total Pages: 373
Release: 2014-08-28
ISBN 10: 149391118X
ISBN 13: 9781493911189
Language: EN, FR, DE, ES & NL

Perinatal Stem Cells Book Review:

This comprehensive volume is one of the first books to offer the reader detailed insight into sources of perinatal stem cells, their biology, and their potential for disease treatment. It examines the research and therapeutic applications of perinatal stem cells including the treatment of renal disease, hematopoietic regeneration, cardiac disease, inflammatory disease, bone regeneration, pulmonary disease, and the treatment of spinal cord injury. Further, the book discusses current progress in the manufacturing, banking and clinical translation of perinatal stem cells. Through this book, readers will gain a thorough understanding of the current pre-clinical and clinical applications of perinatal stem cells as well as the efforts to support the transition of perinatal stem cell therapies from laboratories to clinics. Perinatal Stem Cells contains thirty-two chapters written by internationally recognized leaders in stem cell research. It is organized into four sections covering amniotic fluid stem cells, placental and placental membrane stem cells, umbilical cord stem cells, and clinical translation. This cohesive structure provides an effective framework for detailed insight into this new frontier. Edited by Dr. Anthony Atala, one of the foremost experts in the field, and his co-editor Dr. Sean V. Murphy, this volume is a definitive work for stem cell research and its future implications. It is a key resource for all stem cell researchers, clinicians, and government and industry staff working in this dynamic and exciting field.

Cell Therapy For Lung Disease

Cell Therapy For Lung Disease
Author: Julia M Polak
Publsiher: World Scientific
Total Pages: 528
Release: 2010-03-17
ISBN 10: 1908978287
ISBN 13: 9781908978288
Language: EN, FR, DE, ES & NL

Cell Therapy For Lung Disease Book Review:

The use of stem cells to help with lung regeneration and repair is a novel therapy which could help phase out the need for conventional surgical or pharmacological approaches currently employed to treat diseases of the lung or other organs. The present book explores all avenues of this new form of medical care, moving swiftly, but in depth, from the basic science of lung development, to the analyses of different stem cell types available for regeneration and on to the application of this knowledge base in initial clinical trials.In this volume a stellar group of researchers converge, from different angles, to help towards clarifying the basic mechanisms of lung repair. These range from basic concepts of regeneration and lung development, the analyses of a variety of cell types that may be involved in lung repair, to ways of creating complex lung structures, including artificial and bioartificial lungs. The book offers an insight into repair mechanisms of the diseased lung, the role of specific lung niches and provides information on initial clinical trials as well as the use of stem cells as vehicles for gene therapy. Ingenious technological aspects of assessing stem cell engraftment of stem cell bioprocessing are also included in this volume./a

Cellular Endocrinology in Health and Disease

Cellular Endocrinology in Health and Disease
Author: Alfredo Ulloa-Aguirre,P. Michael Conn
Publsiher: Elsevier
Total Pages: 414
Release: 2014-02-12
ISBN 10: 0124167128
ISBN 13: 9780124167124
Language: EN, FR, DE, ES & NL

Cellular Endocrinology in Health and Disease Book Review:

Cellular Endocrinology in Health and Disease describes the underlying basis of endocrine function, providing an important tool to understand the fundamentals of endocrine diseases. Delivering a comprehensive review of the basic science of endocrinology, from cell biology to human disease, this work explores and dissects the function of a number of cellular systems. Among these are those whose function was not obvious until recently, including the endocrine functions of bone and the adipose tissue. Providing content that crosses disciplines, Cellular Endocrinology in Health and Disease details how cellular endocrine function contributes to system physiology and mediates endocrine disorders. A methods section proves novel and useful approaches across research focus that will be attractive to medical students, residents, and specialists in the field of endocrinology, as well as to those interested in cellular regulation. Editors Alfredo Ulloa-Aguirre and P. Michael Conn, experts in molecular and cellular aspects of endocrinology, deliver contributions carefully selected for relevance, impact, and clarity of expression from leading field experts. Covers systemic endocrine action at the cellular level in both health and disease Delivers information on the integration of cell identity and endocrinology Incorporates recent developments in endocrinology to provide an up-to-date reference to researchers

Innovations in Stem Cell Transplantation

Innovations in Stem Cell Transplantation
Author: Taner Demirer
Publsiher: BoD – Books on Demand
Total Pages: 380
Release: 2013-02-13
ISBN 10: 9535109804
ISBN 13: 9789535109808
Language: EN, FR, DE, ES & NL

Innovations in Stem Cell Transplantation Book Review:

This book documents the increased number of stem cell related research, basic and clinical applications as well as views for the future. The book covers a wide range of issues related to new developments and innovations in cell-based therapies containing basic and clinical chapters from the respected authors involved in stem cell studies and research around the world. It thereby complements and extends the basic coverage of stem cells such as immunogenetics, neuron replacement therapy, cover hematopoietic stem cells, issues related to clinical problems, advanced HLA typing, alternative donor sources as well as gene therapy that employs novel methods in this field. Clearly, the treatment of various malignancies and biomedical engineering will depend heavily on stem cells, and this book is well positioned to provide comprehensive coverage of these developments.

American Journal of Respiratory and Critical Care Medicine

American Journal of Respiratory and Critical Care Medicine
Author: Anonim
Publsiher: Anonim
Total Pages: 329
Release: 2009
ISBN 10:
ISBN 13: UCLA:L0098921166
Language: EN, FR, DE, ES & NL

American Journal of Respiratory and Critical Care Medicine Book Review:

Lung, The: Developmental Morphogenesis, Mechanobiology, And Stem Cells

Lung, The: Developmental Morphogenesis, Mechanobiology, And Stem Cells
Author: El-hashash Ahmed,Meguid Eiman Abdel
Publsiher: World Scientific
Total Pages: 204
Release: 2019-01-29
ISBN 10: 9813277084
ISBN 13: 9789813277083
Language: EN, FR, DE, ES & NL

Lung, The: Developmental Morphogenesis, Mechanobiology, And Stem Cells Book Review:

With detailed scientific background and up-to-date research, this book examines recent developmental and cell biology, mechanobiology and stem cell biology discoveries to help provide a better understanding of lung development, repair and regeneration.Lung regeneration is an urgent therapeutic priority. The current major challenge is the generation of complex vascularized structures that can ultimately support or replace impaired lung function. Recent discoveries in biomedical engineering are analysed within the structural context of the lung to help provide a better understanding of the innovative solutions that could be used for restoring normal morphogenesis and regeneration of the lung. This also includes insights from basic developmental mechanisms of human lung development through the derivation and identification of stem cells, both from the early embryo as well as from differentiated organs and tissues.Suitable for a wide range of readers, including physicians and surgeons, scientists and researchers, and undergraduate and postgraduate students, this guide is an essential read for those working in the field of lung disease and development. remove

Stem Cells in the Lung

Stem Cells in the Lung
Author: Ivan Bertoncello
Publsiher: Springer
Total Pages: 366
Release: 2015-10-31
ISBN 10: 3319210823
ISBN 13: 9783319210827
Language: EN, FR, DE, ES & NL

Stem Cells in the Lung Book Review:

This book presents a comprehensive overview of the current understanding of the organization of endogenous lung stem and progenitor cell compartments during fetal lung development, postnatal lung growth and in adulthood. Progressing stage by stage, the chapters on fetal lung development emphasize the integrated role of epithelial, stromal, vascular and neural cell elements in building a functional lung, while the subsequent chapters on adult lung regeneration describe the nature and properties of adult lung stem/progenitor cells distributed along the proximal-distal axis of the airway tree. The chapters on regulation of lung regeneration and repair discuss how regenerative cells interact with their niche microenvironment and how regulation of lung regeneration and repair in the steady state and following injury recapitulates ontogeny. And, lastly, the chapters on cellular therapies for lung disease and bioengineering the lung focus on promising emerging therapies and approaches in lung regenerative medicine. The scope of this volume of the Stem Cell Biology and Regenerative Medicine series focuses on exploring the topic of building and rebuilding the lung from a cellular rather than a molecular perspective. Thus, the section on cellular therapies does not include extensive coverage of each of the numerous lung diseases, including cancer, which could be amenable to stem cell-based therapies, although the final chapter does include some discussion on the future prospects and challenges. All of the contributors are working on the cutting edge of the lung stem cell field, making this book essential reading for those with an interest in the field of lung stem cell biology and the potential role of cellular therapies and tissue bioengineering approaches in lung regenerative medicine, including biomedical scientists, graduate students, post-graduate researchers and respiratory clinicians.

Science

Science
Author: Anonim
Publsiher: Anonim
Total Pages: 329
Release: 2009
ISBN 10:
ISBN 13: UCSB:31205034615391
Language: EN, FR, DE, ES & NL

Science Book Review:

Stem Cell and Gene Therapy for Cardiovascular Disease

Stem Cell and Gene Therapy for Cardiovascular Disease
Author: Emerson C. Perin,Leslie W. Miller,Doris Taylor,James T. Willerson
Publsiher: Academic Press
Total Pages: 538
Release: 2015-08-21
ISBN 10: 0128018631
ISBN 13: 9780128018637
Language: EN, FR, DE, ES & NL

Stem Cell and Gene Therapy for Cardiovascular Disease Book Review:

Stem Cell and Gene Therapy for Cardiovascular Disease is a state-of-the-art reference that combines, in one place, the breadth and depth of information available on the topic. As stem cell and gene therapies are the most cutting-edge therapies currently available for patients with heart failure, each section of the book provides information on medical trials from contributors and specialists from around the world, including not only what has been completed, but also what is planned for future research and trials. Cardiology researchers, basic science clinicians, fellows, residents, students, and industry professionals will find this book an invaluable resource for further study on the topic. Provides information on stem and gene therapy medical trials from contributors and specialists around the world, including not only what has been completed, but also what is planned for future research and trials Presents topics that can be applied to allogeneic cells, mesenchymal cells, gene therapy, cardiomyoctyes, iPS cells, MAPC's, and organogenesis Covers the three areas with the greatest clinical trials to date: chronic limb ischemia, chronic angina, and acute MI Covers the prevailing opinions on how to harness the body’s natural repair mechanisms Ideal resource for cardiology researchers, basic science clinicians, fellows, residents, students, and industry professionals

Departments of Labor, Health and Human Services, Education, and Related Agencies Appropriations for 2006

Departments of Labor, Health and Human Services, Education, and Related Agencies Appropriations for 2006
Author: United States. Congress. House. Committee on Appropriations. Subcommittee on the Departments of Labor, Health and Human Services, Education, and Related Agencies
Publsiher: Anonim
Total Pages: 329
Release: 2005
ISBN 10:
ISBN 13: MINN:31951D02480528T
Language: EN, FR, DE, ES & NL

Departments of Labor, Health and Human Services, Education, and Related Agencies Appropriations for 2006 Book Review:

Stem Cells and Regenerative Medicine

Stem Cells and Regenerative Medicine
Author: J.-F. Stoltz,Y. Chen,J. Magdalou
Publsiher: IOS Press
Total Pages: 204
Release: 2019-09-04
ISBN 10: 1614999252
ISBN 13: 9781614999256
Language: EN, FR, DE, ES & NL

Stem Cells and Regenerative Medicine Book Review:

As the world’s population ages, the problem of degenerative disease is increasing. At the same time, the demand for organ transplants to repair or replace damaged tissue continues to grow. Regenerative medicine is a branch of translational medicine which promotes the repair, regeneration, or construction of tissues and organs or improves or restores their function through tissue engineering, cell biology, molecular biology and other techniques. Stem cells are one of the most important types of cells used in regenerative medicine, and stem cell research is also one of the most active research areas in the field. This book presents 20 full papers from the 8th International Symposium China-Europe “Stem Cells and Regenerative Medicine”, held in Wuhan, China from 19-21 June 2018. At this symposium, researchers in the field of stem cells and regenerative medicine from China and France discussed research from a molecular point of view and pointed out the clinical applications of mesenchymal stem cells, as well as the construction and applications of new biomaterials, the biomechanics of bone tissue engineering, and cellular immunotherapy, among other subjects. Stem cell technology could soon make possible the repair or replacement of aging and damaged tissue, as well as providing a treatment for genetic defects and malignancies,and this book will be of value to all those with an interest in regenerative medicine.

MicroRNA in Regenerative Medicine

MicroRNA in Regenerative Medicine
Author: Chandan K. Sen
Publsiher: Elsevier
Total Pages: 1288
Release: 2014-11-26
ISBN 10: 0124058582
ISBN 13: 9780124058583
Language: EN, FR, DE, ES & NL

MicroRNA in Regenerative Medicine Book Review:

This work encapsulates the uses of miRNA across stem cells, developmental biology, tissue injury and tissue regeneration. In particular contributors provide focused coverage of methodologies, intervention and tissue engineering. Regulating virtually all biological processes, the genome’s 1048 encoded microRNAs appear to hold considerable promise for the potential repair and regeneration of tissues and organs in future therapies. In this work, 50 experts address key topics of this fast-emerging field. Concisely summarizing and evaluating key findings emerging from fundamental research into translational application, they point to the current and future significance of clinical research in the miRNA area. Coverage encompasses all major aspects of fundamental stem cell and developmental biology, including the uses of miRNA across repair and regeneration, and special coverage of methodologies and interventions as they point towards organ and tissue engineering Multi-colour text layout with 150 colour figures to illustrate important findings Take home messages encapsulate key lessons throughout text Short chapters offer focused discussion and clear ‘voice’

Biotechnological Innovations in Health Care

Biotechnological Innovations in Health Care
Author: Open Universiteit (Heerlen, Netherlands),Thames Polytechnic,BIOTOL (Project)
Publsiher: Anonim
Total Pages: 299
Release: 1991
ISBN 10: 9780750614931
ISBN 13: 0750614935
Language: EN, FR, DE, ES & NL

Biotechnological Innovations in Health Care Book Review:

Merrett provides a concise but comprehensive treatment of one of the central issues in environmental management. Informed by an evolutionary political economy perspective, this text draws on a worldwide range of case studies and examples.

Innovations in Fetal and Neonatal Surgery, An Issue of Clinics in Perinatology - E-Book

Innovations in Fetal and Neonatal Surgery, An Issue of Clinics in Perinatology - E-Book
Author: Hanmin Lee,Ronald B. Hirschl
Publsiher: Elsevier Health Sciences
Total Pages: 179
Release: 2012-07-03
ISBN 10: 1455744271
ISBN 13: 9781455744275
Language: EN, FR, DE, ES & NL

Innovations in Fetal and Neonatal Surgery, An Issue of Clinics in Perinatology - E-Book Book Review:

The Guest Editors have assembled a list of topics that provide state-of-the-art coverage on fetal surgery. Topics covered include fetal cardiac intervention, abdominal wall defects, NEC, esophageal atresia, and spinia bifida. Some articles provide the clinical basics, like general concepts of fetal surgery, while others provide a detailed look at CDH in utero, CDH post natal, ECMO/placenta, stem cell, and anorectal malformations.