Spontaneous Pathology of the Laboratory Non Human Primate

Spontaneous Pathology of the Laboratory Non Human Primate
Author: Alys E. Bradley,Jennifer Chilton
Publsiher: Academic Press
Total Pages: 575
Release: 2020-11-01
ISBN 10: 012813089X
ISBN 13: 9780128130896
Language: EN, FR, DE, ES & NL

Spontaneous Pathology of the Laboratory Non Human Primate Book Review:

Spontaneous Pathology of the Laboratory Nonhuman Primate serves as a "go to" resource for all pathologists working on primates in safety assessment studies. In addition, it helps diagnostic veterinary pathologists rule out spontaneous non-clinical disease pathologies when assigning cause of death to species in zoological collections. Primate species included are rhesus, cynomolgus macaques and marmosets. Multi-authored chapters are arranged by organ system, thus providing the necessary information for continued research. Pathologists often face a lack of suitable reference materials or historical data to determine if pathologic changes they are observing in monkeys are spontaneous or a consequence of other treatments or factors. Contains color illustrations that depict the most common lesions to augment descriptions Covers descriptions that are compliant with the International Harmonization of Nomenclature and Diagnostic Criteria (INHAND) guidelines set forth by the Society of Toxicologic Pathology (STP) Provides pathologists with common terms that are compliant with the FDA’s Standard for Exchange of Nonclinical Data (SEND) guidelines

Nonhuman Primates

Nonhuman Primates
Author: Thomas C. Jones,Ulrich Mohr,Ronald D. Hunt
Publsiher: Springer Science & Business Media
Total Pages: 248
Release: 2012-12-06
ISBN 10: 3642849245
ISBN 13: 9783642849244
Language: EN, FR, DE, ES & NL

Nonhuman Primates Book Review:

The International Life Sciences Institute (ILSI) was estab lished in 1978 to stimulate and support scientific research and educational programs related to nutrition, toxicology, and food safety, and to encourage cooperation in these programs among scientists in universities, industry, and government agencies to assist in the resolution of health and safety issues. To supplement and enhance these efforts, ILSI has made a major commitment to supporting programs to harmonize toxicologic testing, to advance a more uniform interpreta tion of bioassay results worldwide, to promote a common understanding of lesion classifications, and to encourage wide discussion of these topics among scientists. The M on ographs on the Pathology of Laboratory Animals are de signed to facilitate communication among those involved in the safety testing of foods, drugs, and chemicals. The complete set will cover all organ systems and is intended for use by pathologists, toxicologists, and others con cerned with evaluating toxicity and carcinogenicity stud ies. The international nature of the project - as reflected in the composition of the editorial board and the diversity of the authors and editors - strengthens our expectations that understanding and cooperation will be improved worldwide through the series. Alex Malaspina President International Life Sciences Institute Preface This book on nonhuman primate pathology is the 12th volume of a set of monographs prepared under the sponsorship of the International Life Sciences Institute (ILSI).

The Baboon in Biomedical Research

The Baboon in Biomedical Research
Author: John L. VandeBerg,Sarah Williams-Blangero,Suzette D. Tardif
Publsiher: Springer Science & Business Media
Total Pages: 392
Release: 2009-06-04
ISBN 10: 9780387759913
ISBN 13: 0387759913
Language: EN, FR, DE, ES & NL

The Baboon in Biomedical Research Book Review:

Nonhuman primates have played critical roles in biomedical research, and they are among the few animals whose use in research continues to increase. The scienti?c value of nonhuman primates derives from their close phylogenetic proximity to man and their consequent anatomic, physiologic, and genetic similarities to man. Only nonhuman primates can provide adequate models for many complex physiological and disease processes of humans. The baboon is a relative newcomer to the repertoire of nonhuman primates used in biomedical research. However, in less than 50 years since its ?rst use in the U. S. , it has become one of the most popular laboratory primate species. It is larger than the other widely used monkey species, making it advantageous for many types of experiments and technological developments. It is extraordinarily hardy and highly fecund in captivity. It closely resembles humans in a variety of physiological and disease processes, such as cholesterol metabolism, early stages of atherosclerosis, and alcoholic liver disease. Its chromosomes closely resemble those of humans, and many genes of the two species lie in the same chromosomal order. Among all primates, baboons are the most widely used models for the genetics of susceptibility to complex diseases and they are the ?rst nonhuman primate for which a framework genetic linkage map was established. In addition, the baboon genome is currently being sequenced, and as a result the utility of this species for biomedical research will be dramatically increased.

Nonhuman Primates I

Nonhuman Primates I
Author: Thomas C. Jones,Ulrich Mohr,Ronald D. Hunt
Publsiher: Springer Science & Business Media
Total Pages: 221
Release: 2012-12-06
ISBN 10: 3642849067
ISBN 13: 9783642849060
Language: EN, FR, DE, ES & NL

Nonhuman Primates I Book Review:

The International Life Sciences Institute (ILSI) was estab lished in 1978 to stimulate and support scientific research and educational programs related to nutrition, toxicology, and food safety, and to encourage cooperation in these programs among scientists in universities, industry, and government agencies to assist in the resolution of health and safety issues. To supplement and enhance these efforts, ILSI has made a major commitment to supporting programs to harmonize toxicologic testing, to advance a more uniform interpreta tion of bioassay results worldwide, to promote a common understanding of lesion classifications, and to encourage wide discussion of these topics among scientists. The Mo nographs on the Pathology of Laboratory Animals are de signed to facilitate communication among those involved in the safety testing of foods, drugs, and chemicals. The complete set will cover all organ systems and is intended for use by pathologists, toxicologists, and others con cerned with evaluating toxicity and carcinogenicity stu dies. The international nature of the project - as reflected in the composition of the editorial board and the diversity of the authors and editors -strengthens our expectations that understanding and cooperation will be improved worldwide through the series. Alex Malaspina President International Life Sciences Institute Preface This book, on Nonhuman Primates, is the eleventh volume of a set pre pared under the sponsorship of the International Life Sciences Institute (ILSI).

Spontaneous Pathology of the Laboratory Rabbit

Spontaneous Pathology of the Laboratory Rabbit
Author: Alys Bradley
Publsiher: Academic Press
Total Pages: 575
Release: 2022-01-17
ISBN 10: 9780128225288
ISBN 13: 0128225289
Language: EN, FR, DE, ES & NL

Spontaneous Pathology of the Laboratory Rabbit Book Review:

Provides a comprehensive text describing the spontaneous pathology seen in the common laboratory rabbit strains. This is the first book collating information on all organ systems in these strains. Rabbits are widely used for experimentation and testing mainly due to practical, rather than scientific, considerations. They are small and usually docile, easily restrained, cheap to maintain, and breed prodigious. Spontaneous Pathology of the Laboratory Rabbit serves as a "go to” text for all pathologists working on laboratory rabbits in safety assessment studies, and to help diagnostic veterinary pathologists rule out spontaneous non-clinical disease pathology when assigning cause of death to these animals which are also kept as domestic pets. Consist of multi-author chapters arranged by Organ systems Provides color illustrations that depict the most common lesions to augment the descriptions provides pathologists with common terms that are compliant with the FDA's Standard for Exchange of Nonclinical Data (SEND) guidelines Gives references for recommended tissue trimming planes

Primate Models of Children s Health and Developmental Disabilities

Primate Models of Children s Health and Developmental Disabilities
Author: Thomas Burbacher,Kimberly Grant,Gene P. Sackett
Publsiher: Academic Press
Total Pages: 472
Release: 2011-10-10
ISBN 10: 9780080554068
ISBN 13: 0080554067
Language: EN, FR, DE, ES & NL

Primate Models of Children s Health and Developmental Disabilities Book Review:

The rate of neurodevelopmental disabilities, including autism, mental retardation, hearing loss and attention deficit hyperactivity disorder is rising in the United States. Although estimates of the prevalence of these disorders vary, figures from the CDC indicate that 4% of all school age children are developmentally disabled. During infancy, many important milestones in behavioral development are shared between human and nonhuman primates. Learning more about the causes of abnormal development in monkeys has provided important insights into the mechanisms underlying neurodevelopmental disabilities in human infants. This book documents the latest research not commonly found in other references, and provides a comprehensive look at the results from decades of work with nonhuman primates as it relates to child development and disability. Includes hot topics such as early chemical exposures, immunological influences on development, low birth weight, endocrine disrupters, pediatric AIDS, origin of childhood psychopathologies and assisted reproductive technology Represents the significant body of work accumulated since funding for research on developmental disabilities has increased substantially in recent years

Nonhuman Primates in Biomedical Research

Nonhuman Primates in Biomedical Research
Author: Anonim
Publsiher: Elsevier
Total Pages: 512
Release: 1998-07-24
ISBN 10: 9780080537634
ISBN 13: 0080537634
Language: EN, FR, DE, ES & NL

Nonhuman Primates in Biomedical Research Book Review:

This volume and its companion Nonhuman Primates in Biomedical Research: Biology and Management represent the most comprehensive publications of their type on nonhuman primates. This volume addresses the diseases of nonhuman primates with an emphasis on the etiological factors, clinical signs, diagnostic pathology, therapy, and management. Its companion volume serves as a general reference for those who provide care for these animals and for those who use them in biomedical research.

Primates

Primates
Author: Kurt Benirschke
Publsiher: Springer Science & Business Media
Total Pages: 1044
Release: 2012-12-06
ISBN 10: 146124918X
ISBN 13: 9781461249184
Language: EN, FR, DE, ES & NL

Primates Book Review:

This conference represents the first time in my life when I felt it was a misfor tune, rather than a major cause of my happiness, that I do conservation work in New Guinea. Yes, it is true that New Guinea is a fascinating microcosm, it has fascinating birds and people, and it has large expanses of undisturbed rainforest. In the course of my work there, helping the Indonesian government and World Wildlife Fund set up a comprehensive national park system, I have been able to study animals in areas without any human population. But New Guinea has one serious drawback: it has no primates, except for humans. Thus, I come to this conference on primate conservation as an underprivileged and emotionally deprived observer, rather than as an involved participant. Nevertheless, it is easy for anyone to become interested in primate conserva tion. The public cares about primates. More specifically, to state things more realistically, many people care some of the time about some primates. Primates are rivaled only by birds, pandas, and the big cats in their public appeal. For some other groups of animals, the best we can say is that few people care about them, infrequently. For most groups of animals, no one cares about them, ever.

The Nonhuman Primate in Nonclinical Drug Development and Safety Assessment

The Nonhuman Primate in Nonclinical Drug Development and Safety Assessment
Author: Joerg Bluemel,Sven Korte,Emanuel Schenck,Gerhard Weinbauer
Publsiher: Academic Press
Total Pages: 716
Release: 2015-03-13
ISBN 10: 012417146X
ISBN 13: 9780124171466
Language: EN, FR, DE, ES & NL

The Nonhuman Primate in Nonclinical Drug Development and Safety Assessment Book Review:

The Nonhuman Primate in Drug Development and Safety Assessment is a valuable reference dedicated to compiling the latest research on nonhuman primate models in nonclinical safety assessment, regulatory toxicity testing and translational science. By covering important topics such as study planning and conduct, inter-species genetic drift, pathophysiology, animal welfare legislation, safety assessment of biologics and small molecules, immunotoxicology and much more, this book provides scientific and technical insights to help you safely and successfully use nonhuman primates in pharmaceutical toxicity testing. A comprehensive yet practical guide, this book is intended for new researchers or practicing toxicologists, toxicologic pathologists and pharmaceutical scientists working with nonhuman primates, as well as graduate students preparing for careers in this area. Covers important topics such as species selection, study design, experimental methodologies, animal welfare and the 3Rs (Replace, Refine and Reduce), social housing, regulatory guidelines, comparative physiology, reproductive biology, genetic polymorphisms and more Includes practical examples on techniques and methods to guide your daily practice Offers a companion website with high-quality color illustrations, reference values for safety assessment and additional practical information such as study design considerations, techniques and procedures and dosing and sampling volumes

Background Lesions in Laboratory Animals E Book

Background Lesions in Laboratory Animals E Book
Author: Elizabeth Fiona McInnes
Publsiher: Elsevier Health Sciences
Total Pages: 256
Release: 2011-10-24
ISBN 10: 0702049247
ISBN 13: 9780702049248
Language: EN, FR, DE, ES & NL

Background Lesions in Laboratory Animals E Book Book Review:

Background Lesions in Laboratory Animals will be an invaluable aid to pathologists needing to recognize background and incidental lesions while examining slides taken from laboratory animals in acute and chronic toxicity studies, or while examining exotic species in a diagnostic laboratory. It gives clear descriptions and illustrations of the majority of background lesions likely to be encountered. Many of the lesions covered are unusual and can be mistaken for treatment-related findings in preclinical toxicity studies. The Atlas has been prepared with contributions from experienced toxicological pathologists who are specialists in each of the laboratory animal species covered and who have published extensively in these areas. over 600 high-definition, top-quality color photographs of background lesions found in rats, mice, dogs, minipigs, non-human primates, hamsters, guinea pigs and rabbits a separate chapter on lesions in the reproductive systems of all laboratory animals written by Dr Dianne Creasy, a world expert on testicular lesions in laboratory animals a chapter on common artifacts that may be observed in histological glass slides extensive references to each lesion described aging lesions encountered in all laboratory animal species, particularly in rats in mice which are used for carcinogenicity studies

Haschek and Rousseaux s Handbook of Toxicologic Pathology

Haschek and Rousseaux s Handbook of Toxicologic Pathology
Author: Wanda M. Haschek,Colin G. Rousseaux,Matthew A. Wallig,Brad Bolon
Publsiher: Academic Press
Total Pages: 1152
Release: 2021-10-20
ISBN 10: 0128218290
ISBN 13: 9780128218297
Language: EN, FR, DE, ES & NL

Haschek and Rousseaux s Handbook of Toxicologic Pathology Book Review:

Haschek and Rousseaux's Handbook of Toxicologic Pathology: Volume 1: Principles and Practice of Toxicologic Pathology is a key reference on the integration of structure and functional changes in tissues associated with the response to pharmaceuticals, chemicals and biologics. Volume 1 of the Fourth Edition covers the practice of toxicologic pathology in three parts: Principles of Toxicologic Pathology, Methods in Toxicologic Pathology, and the Practice of Toxicologic Pathology. Completely revised with a number of new chapters, Volume 1 of the Handbook of Toxicologic Pathology is an essential part of the most authoritative reference on toxicologic pathology for pathologists, toxicologists, research scientists, and regulators studying and making decisions on drugs, biologics, medical devices, and other chemicals, including agrochemicals and environmental contaminants. Provides new chapters on digital pathology, juvenile pathology, in vitro/in vivo correlation, big data technologies and in-depth discussion of timely topics in the area of toxicologic pathology Offers high-quality and trusted content in a multi-contributed work written by leading international authorities in all areas of toxicologic pathology Features hundreds of full-color images in both the print and electronic versions of the book to highlight difficult concepts with clear illustrations

The Psychological Well Being of Nonhuman Primates

The Psychological Well Being of Nonhuman Primates
Author: National Research Council,Commission on Life Sciences,Institute for Laboratory Animal Research,Committee on Well-Being of Nonhuman Primates
Publsiher: National Academies Press
Total Pages: 184
Release: 1998-11-03
ISBN 10: 0309176506
ISBN 13: 9780309176507
Language: EN, FR, DE, ES & NL

The Psychological Well Being of Nonhuman Primates Book Review:

A 1985 amendment to the Animal Welfare Act requires those who keep nonhuman primates to develop and follow appropriate plans for promoting the animals' psychological well-being. The amendment, however, provides few specifics. The Psychological Well-Being of Nonhuman Primates recommends practical approaches to meeting those requirements. It focuses on what is known about the psychological needs of primates and makes suggestions for assessing and promoting their well-being. This volume examines the elements of an effective care program--social companionship, opportunities for species-typical activity, housing and sanitation, and daily care routines--and provides a helpful checklist for designing a plan for promoting psychological well-being. The book provides a wealth of specific and useful information about the psychological attributes and needs of the most widely used and exhibited nonhuman primates. Readable and well-organized, it will be welcomed by animal care and use committees, facilities administrators, enforcement inspectors, animal advocates, researchers, veterinarians, and caretakers.

Nonhuman Primates in Biomedical Research

Nonhuman Primates in Biomedical Research
Author: Christian R. Abee,Keith Mansfield,Suzette D. Tardif,Timothy Morris
Publsiher: Academic Press
Total Pages: 868
Release: 2012-04-12
ISBN 10: 0123813662
ISBN 13: 9780123813664
Language: EN, FR, DE, ES & NL

Nonhuman Primates in Biomedical Research Book Review:

The 2e of the gold standard text in the field, Nonhuman Primates in Biomedical Research provides a comprehensive, up-to-date review of the use of nonhuman primates in biomedical research. The Diseases volume provides thorough reviews of naturally occurring diseases of nonhuman primates, with a section on biomedical models reviewing contemporary nonhuman primate models of human diseases. Each chapter contains an extensive list of bibliographic references, photographs, and graphic illustrations to provide the reader with a thorough review of the subject. Fully revised and updated, providing researchers with the most comprehensive review of the use of nonhuman primates in bioledical research Addresses commonly used nonhuman primate biomedical models, providing researchers with species-specific information Includes four color images throughout

Pathology for Toxicologists

Pathology for Toxicologists
Author: Elizabeth McInnes
Publsiher: John Wiley & Sons
Total Pages: 216
Release: 2017-03-16
ISBN 10: 1118755316
ISBN 13: 9781118755310
Language: EN, FR, DE, ES & NL

Pathology for Toxicologists Book Review:

Non-pathologists, such as toxicologists and study personnel, can find it difficult to understand the data they receive from pathologists. Toxicological pathologists write long, detailed and highly technical reports. Study personnel are under daily pressure to decide whether lesions described in pathology reports are treatment-related and thus important to the pharmaceutical company or whether the lesions are background changes and thus of little significance. Written by experienced toxicological pathologists, Pathology for Toxicologists: Principles and Practices of Laboratory Animal Pathology for Study Personnel serves to bridge the gap in the understanding of pathology data, enabling non-pathologists to more easily comprehend pathology reports, better integrate pathology data into final study reports and ask pathologists relevant questions about the test compound. This succinct, fully referenced, full colour book is suitable for toxicologists at all stages of their training or career who want to know more about the pathology encountered in laboratory animals used in safety studies. Key features include important chapters on spontaneous and target organ lesions in rats, mice, non-human primates, mini pigs, rabbits and beagle dogs as well as information on general pathology, macroscopic target organ lesions, ancillary pathology techniques, haematology, biochemistry and adversity. Pathology for Toxicologists: Principles and Practices of Laboratory Animal Pathology for Study Personnel includes: Colour diagrams explaining how lesions are caused by either external compounds or spontaneously The anatomic variations and background lesions of laboratory animals Advice on sampling tissues, necropsy, ancillary pathology techniques and recording data A chapter on the haematology and biochemistry of laboratory animals Full colour photographs of common macroscopic lesions encountered in laboratory animals A comprehensive glossary

Guide for the Care and Use of Laboratory Animals

Guide for the Care and Use of Laboratory Animals
Author: National Research Council,Division on Earth and Life Studies,Institute for Laboratory Animal Research,Committee for the Update of the Guide for the Care and Use of Laboratory Animals
Publsiher: National Academies Press
Total Pages: 246
Release: 2011-01-27
ISBN 10: 0309154006
ISBN 13: 9780309154000
Language: EN, FR, DE, ES & NL

Guide for the Care and Use of Laboratory Animals Book Review:

A respected resource for decades, the Guide for the Care and Use of Laboratory Animals has been updated by a committee of experts, taking into consideration input from the scientific and laboratory animal communities and the public at large. The Guide incorporates new scientific information on common laboratory animals, including aquatic species, and includes extensive references. It is organized around major components of animal use: Key concepts of animal care and use. The Guide sets the framework for the humane care and use of laboratory animals. Animal care and use program. The Guide discusses the concept of a broad Program of Animal Care and Use, including roles and responsibilities of the Institutional Official, Attending Veterinarian and the Institutional Animal Care and Use Committee. Animal environment, husbandry, and management. A chapter on this topic is now divided into sections on terrestrial and aquatic animals and provides recommendations for housing and environment, husbandry, behavioral and population management, and more. Veterinary care. The Guide discusses veterinary care and the responsibilities of the Attending Veterinarian. It includes recommendations on animal procurement and transportation, preventive medicine (including animal biosecurity), and clinical care and management. The Guide addresses distress and pain recognition and relief, and issues surrounding euthanasia. Physical plant. The Guide identifies design issues, providing construction guidelines for functional areas; considerations such as drainage, vibration and noise control, and environmental monitoring; and specialized facilities for animal housing and research needs. The Guide for the Care and Use of Laboratory Animals provides a framework for the judgments required in the management of animal facilities. This updated and expanded resource of proven value will be important to scientists and researchers, veterinarians, animal care personnel, facilities managers, institutional administrators, policy makers involved in research issues, and animal welfare advocates.

International Directory of Primatology

International Directory of Primatology
Author: Anonim
Publsiher: Unknown
Total Pages: 200
Release: 1992
ISBN 10: 1928374650XXX
ISBN 13: NWU:35556021779921
Language: EN, FR, DE, ES & NL

International Directory of Primatology Book Review:

The Utilization of Non human Primates in Radiologic Research

The Utilization of Non human Primates in Radiologic Research
Author: Sam Silverman
Publsiher: Unknown
Total Pages: 136
Release: 1983
ISBN 10: 1928374650XXX
ISBN 13: UCAL:X16326
Language: EN, FR, DE, ES & NL

The Utilization of Non human Primates in Radiologic Research Book Review:

Handbook of Laboratory Animal Science Volume III Third Edition

Handbook of Laboratory Animal Science  Volume III  Third Edition
Author: Jann Hau,Steven J. Schapiro
Publsiher: CRC Press
Total Pages: 334
Release: 2013-12-26
ISBN 10: 1466555122
ISBN 13: 9781466555129
Language: EN, FR, DE, ES & NL

Handbook of Laboratory Animal Science Volume III Third Edition Book Review:

While replacing and reducing the use of laboratory animals are integral parts of the 3Rs—replace, reduce, refine—which form the cornerstones of laboratory animal science, biomedical research involving animals remains absolutely essential for the advancement of the medical, veterinary, agricultural, and biological sciences. Building upon the bestselling previous edition, the Handbook of Laboratory Animal Science, Volume III, Third Edition: Animal Models complements volumes I and II of the third edition by completing the task of providing a comprehensive overview of animal models in all biomedical disciplines. The three Rs have been integrated throughout this handbook to promote efficient and humane experimental work with animals. Written by international experts, each chapter focuses on an important subdiscipline of laboratory animal science and can be used as a stand-alone text. This volume contains new chapters for six additional disease animal models: spinal cord injury, cardiovascular diseases, sudden infant death syndrome, developmental disorders, eye diseases, and human cancer. It also presents a new chapter on applying reduction and refinement to animal models. This handbook can be used for undergraduate and postgraduate laboratory animal science courses, and as a handbook for scientists who work with animals in their research, for university veterinarians, for regulators, and for other specialists in laboratory animal science.

Nephrotoxicity in the experimental and clinical situation

Nephrotoxicity in the experimental and clinical situation
Author: P.H. Bach,E.A. Lock
Publsiher: Springer Science & Business Media
Total Pages: 488
Release: 2012-12-06
ISBN 10: 9400933673
ISBN 13: 9789400933675
Language: EN, FR, DE, ES & NL

Nephrotoxicity in the experimental and clinical situation Book Review:

Conn s Handbook of Models for Human Aging

Conn s Handbook of Models for Human Aging
Author: Jeffrey L. Ram,P. Michael Conn
Publsiher: Academic Press
Total Pages: 1218
Release: 2018-04-05
ISBN 10: 0128113545
ISBN 13: 9780128113547
Language: EN, FR, DE, ES & NL

Conn s Handbook of Models for Human Aging Book Review:

Conn's Handbook of Models for Human Aging, Second Edition, presents key aspects of biology, nutrition, factors affecting lifespan, methods of age determination, use in research and the disadvantages/advantages of use. Using a multidisciplinary approach, this updated edition is designed as the only comprehensive, current work that covers the diversity in aging models. Chapters on comparative models explore age-related diseases, including Alzheimer's, joint disease, cataracts, cancer and obesity. Also included are new tricks and approaches not available in primary publications. This must-have handbook is an indispensable resource for researchers interested in the mechanisms of aging, gerontologists, health professionals, allied health practitioners and students. Combines both the methods of study for human aging and animal models Provides a historical overview and discussion of model availability, key methods and ethical issues Contains over 200 full color illustrations