Sex Differences in the Pathophysiology, Presentation, Diagnosis and Management of Cardiac Disease

Sex Differences in the Pathophysiology, Presentation, Diagnosis and Management of Cardiac Diseases provides contemporary data on sex-specific differences in pathophysiology, clinical presentation, diagnostic evaluation and management of cardiovascular diseases, filling a void for clinicians in practice and training. Co-authored by renowned experts in the field (and guideline writers), the text presents state-of-the-art reviews of each topic, encompassing the full spectrum of CVD in men and women. Sex-specific guidelines-based recommendations are highlighted when available. Tailored to meet the needs of busy clinicians and researchers, this text provides concise data, allowing practitioners to more effectively and holistically care for women at risk. Presents a comprehensive, state-of-the-art update on women's heart disease that will serve as an indispensable resource for clinicians and researchers Enables readers to understand sexual dimorphism in pathophysiology, diagnosis, management and outcomes in the full spectrum of cardiovascular issues, including ischemic heart disease, valvular disorders, arrhythmias and heart failure Provides concise, evidence-based practical reviews of medical topics, with attention paid to the role of behavioral health

This book reviews all aspects of the diagnosis and management of heart disease in women, covering areas such as gender differences in metabolic syndrome, hypertension and atherogenesis. Gender differences in cardiovascular diseases are widespread, but while gender medicine takes into account the effects of sex and gender on the health of women and men, traditionally, women have been underrepresented in cardiovascular clinical trials, in management of different cardiac diseases and drug use. Gender Differences in the Pathogenesis and Management of Heart Disease deals with the gender-specific differences in cardiac physiology and diseases and brings into perspective the critical significance of gender in management of cardiovascular disease presentations and management. As such it is of enormous use to all clinical staff who manage women with cardiovascular disease.

Sex Differences in Cardiovascular Physiology and Pathophysiology is a comprehensive look into the often overlooked and underappreciated fundamental sex differences between men and women and how those differences affect the cardiovascular system. It covers cardiovascular function, anatomy, cell signaling and the development of pathology. With contributions from world-renowned research investigators, this up-to-date reference compiles critical knowledge on cardiovascular sex differences, providing researchers and clinicians with a better understanding of the diagnosis, prevention and treatment of cardiovascular diseases in both men and women. Identifies the fundamental sex differences in the physiology and pathophysiology of the cardiovascular system Describes cell signaling pathways involved in sex-associated cardiovascular function and diseases Puts the sex differences in cardiovascular diseases in the forefront to improve cardiovascular prognoses

Cardiovascular disease is the leading cause of death in women in the US, with more women dying from heart disease than men. Women may have different presentation from men and often need a different approach to diagnosis and treatment. There are also unique topics of management of heart disease in women, including issues during pregnancy, lactation, and menopause. Many different health care providers, as well as cardiologists are involved in treating these patients. A manual reviewing diagnosis and treatment of cardiac disease in women would help providers without specific cardiology training to deliver care with greater efficiency. A practical and comprehensive guide geared towards these providers would be a highly practical and valuable resource that would be utilized in everyday practice in offices that include urban clinics, general medicine offices, obstetrics and gynecology offices, as well as in the surgical subspecialties. This book will be a highly practical resource that can be directly applied to the issues that arise in everyday practice. There is no available book on the market that focuses on a broader approach to cardiac disease in women or focuses on non-cardiology providers (and their trainees) who have the need to know more about treatment of cardiovascular disease in women.​

Sex Differences in Cardiovascular Physiology and Pathophysiology is a comprehensive look into the often overlooked and underappreciated fundamental sex differences between men and women and how those differences affect the cardiovascular system. It covers cardiovascular function, anatomy, cell signaling and the development of pathology. With contributions from world-renowned research investigators, this up-to-date reference compiles critical knowledge on cardiovascular sex differences, providing researchers and clinicians with a better understanding of the diagnosis, prevention and treatment of cardiovascular diseases in both men and women. Identifies the fundamental sex differences in the physiology and pathophysiology of the cardiovascular system Describes cell signaling pathways involved in sex-associated cardiovascular function and diseases Puts the sex differences in cardiovascular diseases in the forefront to improve cardiovascular prognoses

In the past two decades a number of studies have shown that abnormalities in the function and structure of coronary microcirculation can be detected in several cardiovascular diseases. On the basis of the clinical setting in which it occurs, coronary microvascular dysfunction (CMD) can be classified into four types: CMD in the absence of any other cardiac disease; CMD in myocardial diseases; CMD in obstructive epicardial coronary artery disease; and iatrogenic CMD. In some instances CMD represents an epiphenomenon, whereas in others it represents an important marker of risk or may contribute to the pathogenesis of myocardial ischemia, thus becoming a possible therapeutic target. This book provides an update on coronary physiology and a systematic assessment of microvascular abnormalities in cardiovascular diseases, in the hope that it will assist clinicians in prevention, detection and management of CMD in their everyday activity.

This is the very first book to deal with sex and gender differences in drug therapy - an increasingly recognized medical need. It starts with an overview on S/G in clinical syndromes and a documentation of the medical and socioeconomic damage caused by gender specific adverse drug effects. Part I covers S/G differences in pharmacokinetics. Researchers will be satisfied by the detailed discussion of the mechanisms of S/G differences in drug effects that represents cutting edge science and includes interaction of drugs with sex hormones, genomic and epigenetic mechanisms. It also covers S/G in drug development, in animal models and clinical development and S/G in drug prescriptions. Part II targets S/G differences in drug effects in cardiovascular, pulmonary, CNS, neuromuscular, neuropsychiatric and metabolic diseases, in cancer, inflammation, and rheumatic diseases, in bacterial and retroviral infections, thrombosis, embolism. New drugs will be discussed.

This book is a concise, easy to read professional text with a focus on practical aspects. All chapters include tables on sex/gender differences in symptoms and management and a series of suggestions to the novice in the field. Chapters are specialty-specific. The focus is not on women’s health, but the presentation of differences in clinical symptoms, management and outcomes in women and men. Gender Medicine strives to employ the knowledge about these differences to improve diagnosis, better understand pathogenesis and advance patient-oriented therapy.

Heart disease is the leading cause of death among US women over the age of 65, resulting in more deaths than all forms of cancer combined. Women are less likely to survive heart attacks than are men, possibly because symptoms in women may differ and may be less recognizable. In addition, women consistently tend to have worse clinical outcomes in percutaneous coronary interventions than do men. For these reasons, an issue on percutaneous interventions in women is timely.

Diagnosis and Management of Adult Congenital Heart Disease, by Drs. Gatzoulis, Webb, and Daubeney, is a practical, one-stop resource designed to help you manage the unique challenges of treating long-term adult survivors of congenital heart disease. Authored by internationally known leaders in the field, this edition is the first that truly integrates anatomy and imaging technology into clinical practice, and includes new chapters on cardiac CT for ACHD assessment, critical and perioperative care, anesthesia for ACHD surgery, cardiac resynchronization therapy, and transition of care. Congenital defects are presented with high-quality illustrations and appropriate imaging modalities. Find all the information you need in one user-friendly resource that integrates anatomy, clinical signs, and therapeutic options. Confidently make decisions aided by specific recommendations about the benefits and risks of surgeries, catheter interventions, and drug therapy for difficult clinical problems. Recognize and diagnose morphologic disorders with the help of detailed, full-color diagrams. Quickly find what you need thanks to easily accessible, consistently organized chapters and key annotated references. Keep pace with the latest advancements including five new chapters on cardiac CT for ACHD assessment, critical and perioperative care, anaesthesia for ACHD surgery, cardiac resynchronisation therapy, and transition of care Comply with the latest European Society of Cardiology (ESC) and American College of Cardiology (ACC) practice guidelines - integrated throughout the book - for cardiac pacing and cardiac resynchronisation therapy See imaging findings as they appear in practice and discern subtle nuances thanks to new, high-quality images and illustrations Integrates anatomy, clinical signs and therapeutic options of congenital heart disease both in print and online!

A combination color atlas and synoptic text on the unique risk factors and cardiovascular issues specific to women Recent research has demonstrated important sex differences in the pathophysiology and clinical presentation of cardiovascular disease in women. There are important risk factors for cardiovascular disease in women that differ from men, and risk assessment tools that should be routinely incorporated into clinical practice by cardiologists treating women. Color Atlas and Synopsis of Women's Cardiovascular Health covers all of these topics and also provides concise, expert guidance on the diagnosis and management of the female cardiac patient. Enriched by more than 100 photographs (many in full color) and nearly 100 line drawings, Color Atlas and Synopsis of Women's Cardiovascular Health addresses many important issues related to women's cardiovascular health. With contributions from more than a dozen expert authors, Color Atlas and Synopsis of Women's Cardiovascular Health is destined to become a landmark reference on the issues of cardiac disease in women. TOPICS INCLUDE: Defining patterns of ischemic heart disease Cardiac surgery Noninvasive imaging as a tool for accurate diagnosis of cardiovascular disease in women Sex-specific issues in cardiac surgery Unique cardiac issues related to women with pulmonary hypertension Cardiac issues that can arise during pregnancy

Sex and Cardiac Electrophysiology: Differences in Cardiac Electrical Disorders Between Men and Women is a comprehensive investigation into all aspects of sex differences in cardiac electrophysiology. As there are substantial differences between female and male patients in physiology, pathology triggering factors, disease progression, clinical approaches and treatment outcome, this book provides a comprehensive examination. In cardiology, the differences between women and men are more recognized, hence this title summarizes these important differences, providing the essential information needed for clinical specialists and researchers involved in the design and implementation of clinical studies. Explores topics ranging from the physiologic differences between women and men to the differences in clinical handling of arrhythmic disorders between female and male patients Provides sex differences in cardiac electrophysiology in separate chapters Covers the sex differences of cardiac electrical disorders, providing insights beyond cardiac metabolic syndrome, hypertension, atherogenesis and heart failure

Written by leading authorities in the field, Chest Pain with Normal Coronary Arteries comprehensively reviews the clinical presentation and the pathogenesis of the condition, as well as its management. This book provides a practical tool for the clinician and a bank of information and new ideas for research scientists and clinical researchers interested in understanding the causes and mechanisms of chest pain with normal coronary arteries. Whether the pain be of gastroenterologic, cardiac or endocrine in origin, the book focuses on effective diagnosis, treatment and management of different pathologies in patients. Chest Pain with Normal Coronary Arteries is an essential read for all clinicians involved in managing patients with chest pain, and those that should be aware of non-cardiac chest pain.

Principles of Gender-Specific Medicine examines how normal human biology differs between men and women and how the diagnosis and treatment of disease differs as a function of gender. This revealing research covers various conditions that predominantly occur in men, and as well conditions that predominantly occur in women. Among the subjects covered are cardiovascular disease, mood disorders, the immune system, lung cancer as a consequence of smoking, osteoporosis, diabetes, obesity, and infectious diseases. * Gathers important information in the field of gender-based biology and clinical medicine, proving that a patient's sex is increasingly important in preventing illness, making an accurate diagnosis, and choosing safe and effective treatment of disease * Addresses gender-specific areas ranging from organ transplantation, gall bladder and biliary diseases, to the epidemiology of osteoporosis and fractures in men and women * Many chapters present questions about future directions of investigations

Women and Health is a comprehensive reference which addresses health issues affecting women of all ages--adolescence through maturity. It goes far beyond other books on this topic which concentrate only on reproductive health, and has a truly international perspective. It covers key issues ranging from osteoporosis to breast cancer and other cancers, domestic violence, sexually transmitted diseases, occupational hazards, eating disorders, heart disease and other chronic illnesses, substance abuse, and societal and behavioral influences on health. Women and Health covers not only those conditions that are unique to or occur more frequently in women, but also those that present differently or are treated differently in women. Key Features: * Comprehensive, in-depth review of all aspects of women's health * Highlights key women's health issues including osteoporosis, domestic violence, breast cancer, menopause, infertility, heart disease, and many others * Addresses international women's health issues from a human rights and cultural perspective * Presents the latest research and clinical findings from leaders in their respective fields * Highlights controversies in treatment modalities * Challenges the medical community to address the impact of gender on health * Expands our thinking about the perceptions of disease and disorders in women * Challenges current status quo in health care delivery

Cardiology’s cornerstone text – thoroughly updated to reflect the latest clinical perspectives and cutting-edge topics Hailed for its authority, currency, and ability to translate the latest technical and clinical advances into clinical application, Hurst’s The Heart is the field’s landmark text and cardiology’s longest continuously published reference text. A previous edition of this trusted classic was described by Doody’s as “an outstanding choice for those who strive for a firm foundation in cardiovascular medicine, as well as an up-to-date and user-friendly source that addresses every discipline in the field.” Readers will find succinct, visually appealing summaries of all the major new trials, and guidelines, along with tips for optimizing outcomes and health quality. The Fourteenth Edition has been completely updated to reflect the latest technical, therapeutic, and clinical advances, while still maintaining a strong focus on patient care. Other enhancements include the addition of textual features such as Practice Points, Common Clinical Questions, and an increased number of the acclaimed Hurst’s diagrams. • NEW TO THIS EDITION: Section on Metabolic Disorders and Cardiovascular Disease, Cigarette Smoking and Cardiovascular Disease • Enhanced by more than 1,500 full-color illustrations and more than 500 tables • Brand new chapters include: Arrythmogenic Cardiomyopathy, Ischemic Mitral Regurgitation, Degenerative Mitral Valve Disease, Left Ventricular Noncompaction, Evaluation and Management of Acute Heart Failure, Carotid Artery Stenting, Race, Ethnicity, and Cardiovascular disease • The only comprehensive cardiology reference to publish every 2.5 years to allow for reporting of the latest trials and guidelines

This practical resource takes a close look at an emerging issue in woman's health*the gender difference in cardiovascular disease. Health care providers involved in the care of female patients can rely on this extraordinary reference for the latest coverage of cardiovascular health and disease. The new 2nd Edition features an expanded scope that offers more information on patient care approaches, risk factors, hormones and CAD, and more. New chapters cover hot topics such as estrogen, diet and nutrition, first- and second-degree prevention strategies, managing CAD, and acute coronary syndromes. A much broader scope presents more information on patient care, risk factors, hormones and CAD, and clinical manifestations of CAD. New authors bring an up-to-date perspective to material that focuses on their areas of expertise. New chapters provide the latest information on hot topics, including: Nutrition, Antioxidants and Inflammation, Primary Prevention in Women, Lessons from Human Trials, Management of Chronic Stable Angina, Acute Coronary Syndromes, Angiography and Angioplasty, Coronary Artery Surgery, Implementation Strategies for Secondary Prevention, Syndrome X and Coronary Vascular Resistance, and Normal Cardiovascular Physiology Updates and new information have been incorporated throughout, and substantial revisions have been made to chapters on: Diabetes Mellitus and Obesity, Smoking, Clotting and Thrombosis, Physical Activity, Lessons from Animal Models, Prescribing HRT, Diagnostic Testing Valvular Heart Disease, CHF and Myocardial Dysfunction, Stroke and PVD, Preexisting Heart Disease, and Diagnostic and Therapeutic Strategies Expanded discussions of estrogen address both the underlying science and clinical applications for practice Strategies for first- and second-degree prevention of disease offer a proactive approach to treatment and patient care

This is a groundbreaking book which explains the important clinical and surgical aspects of the diagnosis and treatment of heart disease in women, and seeks to improve the understanding of the difference gender makes to both the presentation of heart disease and the disease itself.