SERS for Point of care and Clinical Applications

SERS for Point of care and Clinical Applications
Author: Andrew Fales
Publsiher: Elsevier
Total Pages: 316
Release: 2021-01-15
ISBN 10: 9780128205488
ISBN 13: 0128205482
Language: EN, FR, DE, ES & NL

SERS for Point of care and Clinical Applications Book Review:

SERS for Point-of-care and Clinical Applications focuses on the current uses of Surface-Enhanced Raman Spectroscopy (also known as Surface-Enhanced Raman Scattering) techniques in the clinical and point-of-care settings. In recent years, improvements in detector technology and nanostructure fabrication have expanded the possibilities of using SERS in biomedical applications. These applications are not always immediately evident to newcomers in the field, as Raman and SERS are often introduced as analytical methods for chemical analysis. This book offers a concise introduction to the biomedical applications of SERS for graduate students, scientists, and researchers in all related fields. Readers are first presented with an overview of SERS biomedical applications, and the remaining sections provide in-depth information about point-of-care and clinical applications of SERS using specific examples from the current literature. The first book of its kind to highlight point-of-care applications of SERS Covers the recent biomedical applications of SERS carried out by leaders in the field Includes chapters on SERS probes and labels and label-free uses of SERS

Principles and Clinical Diagnostic Applications of Surface Enhanced Raman Spectroscopy

Principles and Clinical Diagnostic Applications of Surface Enhanced Raman Spectroscopy
Author: Yuling Wang
Publsiher: Elsevier
Total Pages: 464
Release: 2021-09-17
ISBN 10: 012823198X
ISBN 13: 9780128231982
Language: EN, FR, DE, ES & NL

Principles and Clinical Diagnostic Applications of Surface Enhanced Raman Spectroscopy Book Review:

Principles and Clinical Diagnostic Applications of Surface-Enhanced Raman Spectroscopy summarizes the principles of surface-enhanced Raman scattering/spectroscopy (SERS) and plasmonic nanomaterials for SERS, with a focus on SERS applications in clinical diagnostics. This book covers the key concepts from the fundamentals, materials, experimental aspects, and applications of SERS in clinical diagnostics with discussions on label-free/direct SERS assay, design and synthesis of SERS nanotags, SERS nanotags for point-of-care diagnostics, microfluidic SERS assay, and in vitro and in vivo sensing and imaging. Written by experts from around the world, this comprehensive volume showcases the recent progress of SERS applications in clinical diagnostics and helps readers understand when and how to use SERS in a clinical setting. Introduces the basics of SERS and suitable nanomaterials for SERS application Gives an overview of the cutting-edge research on SERS applications for clinical diagnosis, including the latest advances in our understanding of underlying principles to enable material design and clinical applications Gradually builds from the fundamental concepts to the applications of SERS for clinical diagnostics

Use of Surface Enhanced Raman Spectroscopy for the Detection of Bioactive Lipids

Use of Surface Enhanced Raman Spectroscopy for the Detection of Bioactive Lipids
Author: Christopher M. Ohlhaver
Publsiher: Unknown
Total Pages: 135
Release: 2018
ISBN 10: 1928374650XXX
ISBN 13: OCLC:1050953299
Language: EN, FR, DE, ES & NL

Use of Surface Enhanced Raman Spectroscopy for the Detection of Bioactive Lipids Book Review:

The detection and analysis of lipids in biological matrices for clinical applications poses many challenges, but rapid and reliable detection will prove invaluable for clinical diagnosis. Herein, we report the application of drop-casted Ag nanoplatelets as surface enhanced Raman scattering (SERS) substrates for qualitative detection of 20-hydroxyeicosatetraenoic acid (20-HETE), which is a potential biomarker for diagnosis of hypertensive disorders. Biomarker peaks of 20-HETE can be reliably detected and differentiated from those of the structurally similar lipids (arachidonic acid, eicosapentaenoic acid, and docosahexaenoic acid) commonly found in human blood, even 1 pM concentrations. Additionally, one study mixed 20-HETE with three structurally similar lipids at concentrations several orders of magnitude greater than the target lipid and 20-HETE could still be detected under these conditions. These experiments demonstrate the viability of SERS for the rapid and reliable detection of endogenous bioactive lipids, which has significant clinical impact in enabling point of care diagnostics.

Next Generation Point of care Biomedical Sensors Technologies for Cancer Diagnosis

Next Generation Point of care Biomedical Sensors Technologies for Cancer Diagnosis
Author: Pranjal Chandra,Yen Nee Tan,Surinder P. Singh
Publsiher: Springer
Total Pages: 396
Release: 2017-12-30
ISBN 10: 981104726X
ISBN 13: 9789811047268
Language: EN, FR, DE, ES & NL

Next Generation Point of care Biomedical Sensors Technologies for Cancer Diagnosis Book Review:

This book presents recent research on cancer detection methods based on nanobiosensors, which offer ultrasensitive point-of-care diagnosis. Several methods for diagnosing cancer have been discovered and many more are currently being developed. Conventional clinical approaches to detecting cancers are based on a biopsy followed by histopathology, or on the use of biomarkers (protein levels or nucleic acid content). Biopsy is the most widely used technique; however, it is an invasive technique and is not always applicable. Furthermore, biomarker-based detection cannot be relied on when the biomarkers are present in an extremely low concentration in the body fluids and in malignant tissues. Thus, in recent years highly sensitive and robust new cancer diagnosis techniques have been developed for clinical application, and may offer an alternative strategy for cancer diagnosis. As such, this book gathers the latest point-of-care cancer diagnostic methods and protocols based on biomedical sensors, microfluidics, and integrated systems engineering. It also discusses recent developments and diagnostics tests that can be conducted outside the laboratory in remote areas. These technologies include electrochemical sensors, paper-based microfluidics, and other kit-based diagnostic methods that can be adapted to bring cancer detection and diagnostics to more remote settings around the globe. Overall, the book provides students, researchers, and clinicians alike a comprehensive overview of interdisciplinary approaches to cancer diagnosis.

Surface Enhanced Raman Spectroscopy Biosensing and Diagnostic Technique for Healthcare Applications

Surface Enhanced Raman Spectroscopy  Biosensing and Diagnostic Technique for Healthcare Applications
Author: Swati Jain
Publsiher: Bentham Science Publishers
Total Pages: 265
Release: 2021-12-28
ISBN 10: 9815039121
ISBN 13: 9789815039122
Language: EN, FR, DE, ES & NL

Surface Enhanced Raman Spectroscopy Biosensing and Diagnostic Technique for Healthcare Applications Book Review:

Surface enhanced Raman spectroscopy (SERS) is a technique applied in multidisciplinary research. Its use has tremendously grown in the last 40 years owing to improved nanofabrication, biomolecules extraction and sensitive signal acquisition techniques. This book focuses on the underlying principles of SERS by emphasizing on basic concepts and background information about the subject. Chapters explain the physics of Raman spectroscopy while also indicating its relevance to designing protocols and methodologies for biosensing and imaging. The book gives updated and recent details on colloids and nanostructures, their fabrication, surface engineering and immobilization methods, all in context to SERS based biosensing. Key Features: - Covers basic knowledge and new research about surface enhanced Raman spectroscopy (SERS) - Provides a complete framework on SERS based biosensing with concise chapters - Focuses on different active molecules critical to SERS and associated developed nanoassemblies - Presents information about ongoing research on SERS imaging applications - Highlights bottlenecks of SERS technique in biosensing - Includes references for further reading This book serves as a reference book for researchers and academicians and will also provide a reasonable understanding on the topic of SERS to newcomers irrespective of their background in a simple manner. The book is of interest to all readers within the scientific community involved with Raman spectroscopy, including chemists, physicists, biologists, material scientists as well as biomedical engineers.

Nanobiomaterials

Nanobiomaterials
Author: Xiumei Wang,Murugan Ramalingam,Xiangdong Kong,Lingyun Zhao
Publsiher: John Wiley & Sons
Total Pages: 238
Release: 2017-11-21
ISBN 10: 3527698639
ISBN 13: 9783527698639
Language: EN, FR, DE, ES & NL

Nanobiomaterials Book Review:

Written by an international team of editors and contributors from renowned universities and institutes, this book addresses the latest research in the field of nanobiomaterials, covering nanotechnologies for their fabrication, developments in biomedical applications, and the challenges of biosafety in clinic uses. Clearly structured, the volume defines the scope and classification of the field, resulting in a broad overview from fundamental principles to current technological advances, and from materials synthesis to biomedical applications along with future trends.

Nanotechnology in Cancer Management

Nanotechnology in Cancer Management
Author: Kamil Reza Khondakar,Ajeet Kumar Kaushik
Publsiher: Elsevier
Total Pages: 252
Release: 2021-05-18
ISBN 10: 0128181559
ISBN 13: 9780128181553
Language: EN, FR, DE, ES & NL

Nanotechnology in Cancer Management Book Review:

Nanotechnology in Cancer Management: Precise Diagnostics toward Personalized Health Care provides a well-focused and comprehensive overview of technologies involved in early stage cancer diagnostics via the detection of various cancer biomarkers, both in-vitro and in-vivo. The book briefly describes the advancement in cancer biomarker research relating to cancer diagnostics, covering fundamental aspects of various techniques, especially transduction methodologies, such as electrochemical, optical, magnetic, etc. In addition, it describes approaches on how to make options cost-effective, scalable for clinical application, and user-friendly. Advancements in technology related to device miniaturization, performance improvement and point-of-care applications round out discussions. Final sections cover future challenges, the prospects of various techniques, and how the introduction of nanotechnology in cancer management in a personalized manner is useful. Includes smart sensing materials such as smart electro-active nanomaterials, sensitive transducers development, nano-enabled advanced imaging, miniaturized analytical system, and device integration and interfacing for point-of-care applications Describes each component involved in the development of an efficient cancer diagnostics system Focuses on fundamental and applied concepts of the technologies, along with the related mechanisms proposed for diagnostics of cancer Enhances fundamental understandings of the concepts and development of nanotechnology based analytical tools and novel techniques for early stage cancer diagnostics and management

Applications of Nanoscience in Photomedicine

Applications of Nanoscience in Photomedicine
Author: Michael R. Hamblin,Pinar Avci
Publsiher: Elsevier
Total Pages: 220
Release: 2015-02-17
ISBN 10: 1908818786
ISBN 13: 9781908818782
Language: EN, FR, DE, ES & NL

Applications of Nanoscience in Photomedicine Book Review:

Nanoscience has become one of the key growth areas in recent years. It can be integrated into imaging and therapy to increase the potential for novel applications in the field of photomedicine. In the past commercial applications of nanoscience have been limited to materials science research only, however, in recent years nanoparticles are rapidly being incorporated into industrial and consumer products. This is mainly due to the expansion of biomedical related research and the burgeoning field of nanomedicine. Applications of Nanoscience in Photomedicine covers a wide range of nanomaterials including nanoparticles used for drug delivery and other emerging fields such as optofluidics, imaging and SERS diagnostics. Introductory chapters are followed by a section largely concerned with imaging, and finally a section on nanoscience-enabled therapeutics. Covers a comprehensive up-to-date information on nanoscience Focuses on the combination of photomedicine with nanotechnology to enhance the diversity of applications Pioneers in the field have written their respective chapters Opens a plethora of possibilities for developing future nanomedicine Easy to understand and yet intensive coverage chapter by chapter

Development Characterization and Optimization of Novel Surface Enhanced Raman Scattering SERS Direct and Indirect Assays

Development  Characterization  and Optimization of Novel Surface Enhanced Raman Scattering  SERS  Direct and Indirect Assays
Author: Virginia Lyn Schmit
Publsiher: Unknown
Total Pages: 106
Release: 2011
ISBN 10: 9781267048479
ISBN 13: 1267048476
Language: EN, FR, DE, ES & NL

Development Characterization and Optimization of Novel Surface Enhanced Raman Scattering SERS Direct and Indirect Assays Book Review:

The objective of this study was to develop direct and indirect capture assays for use with Surface Enhanced Raman Scattering (SERS) spectroscopy. Spectroscopically bright gold nanoparticle reporters may be used as detectors for any number of SERS assays. Direct capture assays directly couple the compound of interest to gold coating a sample concentrator. For our proof of concept direct capture assay, we detected cyanide in an aqueous solution. Indirect capture assays couple a Raman reporter (gold nanoparticle tagged with a Raman active compound) to the sample concentrator via antibody antigen interactions. The Raman reporter presents a unique spectrum when excited by an 808 nm laser, and the complex is pulled out of solution using a three separate approaches, paramagnetic, buoyant and neutrally buoyant--the latter two are novel sample concentrating approaches and will be discussed in further detail within this report. The paramagnetic particles are strongly attracted to a magnet and thus the complex is pulled out of solution for interrogation with the laser. The buoyant design physically separates the positively coupled reaction from non-coupled nanoparticles. In the indirect coupled assays, the Raman reporter provides the unique spectrum for identification, and in future work, the assays can be multiplexed. Each compound of interest will be coupled to a unique Raman reporter that will allow multiplexing of this assay development. The method of detection will be SERS. SERS was chosen as the method of choice due to its high sensitivity and selectivity. The ultimate application of this technology will be for use in point of care diagnostics in the emergency department at hospitals, in ambulances, or in developing countries for diagnostic assessment of pathogenic human diseases in small, clinical settings. In this manner, the complex SERS spectra from a multiplexed assay will be reduced to an 'answer box' indicating presence or absence of a marker of interest.

Surface Enhanced Raman Scattering New Theoretical Approaches Materials and Strategies

Surface Enhanced Raman Scattering  New Theoretical Approaches  Materials and Strategies
Author: Ivano Alessandri,John Lombardi
Publsiher: Frontiers Media SA
Total Pages: 135
Release: 2020-03-25
ISBN 10: 2889635538
ISBN 13: 9782889635535
Language: EN, FR, DE, ES & NL

Surface Enhanced Raman Scattering New Theoretical Approaches Materials and Strategies Book Review:

Applications of Microfluidic Systems in Biology and Medicine

Applications of Microfluidic Systems in Biology and Medicine
Author: Manabu Tokeshi
Publsiher: Springer
Total Pages: 382
Release: 2019-04-25
ISBN 10: 9811362297
ISBN 13: 9789811362293
Language: EN, FR, DE, ES & NL

Applications of Microfluidic Systems in Biology and Medicine Book Review:

This book focuses on state-of-the-art microfluidic research in medical and biological applications. The top-level researchers in this research field explain carefully and clearly what can be done by using microfluidic devices. Beginners in the field —undergraduates, engineers, biologists, medical researchers—will easily learn to understand microfluidic-based medical and biological applications. Because a wide range of topics is summarized here, it also helps experts to learn more about fields outside their own specialties. The book covers many interesting subjects, including cell separation, protein crystallization, single-cell analysis, cell diagnosis, point-of-care testing, immunoassay, embyos/worms on a chip and organ-on-a-chip. Readers will be convinced that microfluidic devices have great potential for medical and biological applications.

Nanotechnology Characterization Tools for Biosensing and Medical Diagnosis

Nanotechnology Characterization Tools for Biosensing and Medical Diagnosis
Author: Challa S.S.R. Kumar
Publsiher: Springer
Total Pages: 592
Release: 2018-05-02
ISBN 10: 3662563339
ISBN 13: 9783662563335
Language: EN, FR, DE, ES & NL

Nanotechnology Characterization Tools for Biosensing and Medical Diagnosis Book Review:

Eighth volume of a 40 volume series on nanoscience and nanotechnology, edited by the renowned scientist Challa S.S.R. Kumar. This handbook gives a comprehensive overview about Nanotechnology Characterization Tools for Biosensing and Medical Diagnosis. Modern applications and state-of-the-art techniques are covered and make this volume an essential reading for research scientists in academia and industry.

Nanomaterials in Diagnostic Tools and Devices

Nanomaterials in Diagnostic Tools and Devices
Author: Suvardhan Kanchi,D. Sharma
Publsiher: Elsevier
Total Pages: 618
Release: 2020-06-15
ISBN 10: 0128179236
ISBN 13: 9780128179239
Language: EN, FR, DE, ES & NL

Nanomaterials in Diagnostic Tools and Devices Book Review:

Nanomaterials in Diagnostic Tools and Devices provides a complete overview of the significance of nanomaterials in fabricating selective and performance enhanced nanodevices. It is an interdisciplinary reference that includes contributing subjects from nanomaterials, biosensors, materials science, biomedical instrumentation and medicinal chemistry. This book is authored by experts in the field of nanomaterial synthesis, modeling, and biosensor applications, and provides insight to readers working in various science fields on the latest advancements in smart and miniaturized nanodevices. These devices enable convenient real-time diagnosis of diseases at clinics rather than laboratories, and include implantable devices that cause less irritation and have improved functionality. Research in the field of nanomaterials is growing rapidly, creating a significant impact across different science disciplines and nanotechnology industries. This synthesis and modeling of nanomaterials has led to many technology breakthroughs and applications, especially in medical science. Provides a distinctive platform for the latest trends in the synthesis of smart nanomaterials for nanodevices in disease diagnostics Presents a broad range of advancements and applications of lateral-flow nanostrip for point-of-care applications Examines smart-phone based nanodevices for field-based diagnosis with accurate information Comprises more than 70 figures and illustrations that will help readers visualize and easily understand the role of nanodevices in the field of nanomedicine Serves as an ideal reference for those studying smart nanomaterials, biosensors, and nanodevices for real-time and in-situ clinical diagnosis and drug delivery

The Clinical Nanomedicine Handbook

The Clinical Nanomedicine Handbook
Author: Sara Brenner
Publsiher: CRC Press
Total Pages: 365
Release: 2013-12-13
ISBN 10: 1439834792
ISBN 13: 9781439834794
Language: EN, FR, DE, ES & NL

The Clinical Nanomedicine Handbook Book Review:

Designed to foster a stronger awareness and exploration of the subject by practicing clinicians, medical researchers and scientists, The Clinical Nanomedicine Handbook discusses the integration of nanotechnology, biology, and medicine from a clinical point of view. The book highlights relevant research and applications by specialty; it examines nanotechnology in depth, and the potential to solve medical problems. It also increases literacy in nanotechnology, and allows for more effective communication and collaboration between disciplines. Details worldwide developments in nanomedicine Provides a comprehensive roadmap of the state of nanomedicine in numerous medical specialties Bridges the gap between basic science research, engineering, nanotechnology, and medicine This text discusses what nanomedicine is, how it is currently used, and considers its potential for future applications. It serves as a reference for clinicians, including physicians, nurses, health-care providers, dentists, scientists, and researchers involved in clinical applications of nanotechnology.

New Technologies in Cancer Diagnostics and Therapeutics

New Technologies in Cancer Diagnostics and Therapeutics
Author: Dong-Hua Yang,Pascale Cohen,Haichang Li,Yingyan Yu
Publsiher: Frontiers Media SA
Total Pages: 135
Release: 2021-10-21
ISBN 10: 2889715248
ISBN 13: 9782889715244
Language: EN, FR, DE, ES & NL

New Technologies in Cancer Diagnostics and Therapeutics Book Review:

Synthesis and Modification of Nanostructured Thin Films

Synthesis and Modification of Nanostructured Thin Films
Author: Ion N. Mihailescu
Publsiher: MDPI
Total Pages: 276
Release: 2020-03-17
ISBN 10: 3039284541
ISBN 13: 9783039284542
Language: EN, FR, DE, ES & NL

Synthesis and Modification of Nanostructured Thin Films Book Review:

The Special Issue “Synthesis and Modification of Nanostructured Thin Films” highlights the recent progress in thin film synthesis/modification and characterization. New methods are reviewed for the synthesis and/or modification of thin films based on laser, magnetron, chemical, and other techniques. The obtained thin nanostructures are characterized by complex and complementary techniques. We think that most of proposed methods can be directly applied in production, but some others still need further elaboration for long-term prospective applications in lasers, optics, materials, electronics, informatics, telecommunications, biology, medicine, and probably many other domains. The Guest Editor and the MDPI staff are therefore pleased to offer this Special Issue to interested readers, including graduate and PhD students as well as postdoctoral researchers, but also to the entire community interested in the field of nanomaterials. We share the conviction that this can serve as a useful tool for updating the literature, but also to aid in the conception of new production and/or research programs. There is plenty of room for further dedicated R&D advances based on new instruments and materials under development.

Point of care testing

Point of care testing
Author: Peter Luppa,Ralf Junker
Publsiher: Springer
Total Pages: 445
Release: 2018-07-18
ISBN 10: 3662544970
ISBN 13: 9783662544976
Language: EN, FR, DE, ES & NL

Point of care testing Book Review:

The underlying technology and the range of test parameters available are evolving rapidly. The primary advantage of POCT is the convenience of performing the test close to the patient and the speed at which test results can be obtained, compared to sending a sample to a laboratory and waiting for results to be returned. Thus, a series of clinical applications are possible that can shorten the time for clinical decision-making about additional testing or therapy, as delays are no longer caused by preparation of clinical samples, transport, and central laboratory analysis. Tests in a POC format can now be found for many medical disciplines including endocrinology/diabetes, cardiology, nephrology, critical care, fertility, hematology/coagulation, infectious disease and microbiology, and general health screening. Point-of-care testing (POCT) enables health care personnel to perform clinical laboratory testing near the patient. The idea of conventional and POCT laboratory services presiding within a hospital seems contradictory; yet, they are, in fact, complementary: together POCT and central laboratory are important for the optimal functioning of diagnostic processes. They complement each other, provided that a dedicated POCT coordination integrates the quality assurance of POCT into the overall quality management system of the central laboratory. The motivation of the third edition of the POCT book from Luppa/Junker, which is now also available in English, is to explore and describe clinically relevant analytical techniques, organizational concepts for application and future perspectives of POCT. From descriptions of the opportunities that POCT can provide to the limitations that clinician’s must be cautioned about, this book provides an overview of the many aspects that challenge those who choose to implement POCT. Technologies, clinical applications, networking issues and quality regulations are described as well as a survey of future technologies that are on the future horizon. The editors have spent considerable efforts to update the book in general and to highlight the latest developments, e.g., novel POCT applications of nucleic acid testing for the rapid identification of infectious agents. Of particular note is also that a cross-country comparison of POCT quality rules is being described by a team of international experts in this field.

Surface Enhanced Vibrational Spectroscopy

Surface Enhanced Vibrational Spectroscopy
Author: Ricardo Aroca
Publsiher: John Wiley & Sons
Total Pages: 260
Release: 2006-05-01
ISBN 10: 9780470035658
ISBN 13: 047003565X
Language: EN, FR, DE, ES & NL

Surface Enhanced Vibrational Spectroscopy Book Review:

Surface Enhanced Vibrational Spectroscopy (SEVS) has reached maturity as an analytical technique, but until now there has been no single work that describes the theory and experiments of SEVS. This book combines the two important techniques of surface-enhanced Raman scattering (SERS) and surface-enhanced infrared (SEIR) into one text that serves as the definitive resource on SEVS. Discusses both the theory and the applications of SEVS and provides an up-to-date study of the state of the art Offers interpretations of SEVS spectra for practicing analysts Discusses interpretation of SEVS spectra, which can often be very different to the non-enhanced spectrum - aids the practicing analyst

Advancing Gene Fusion Detection Towards Personalized Cancer Nanodiagnostics

Advancing Gene Fusion Detection Towards Personalized Cancer Nanodiagnostics
Author: Kevin M. Koo
Publsiher: Springer Nature
Total Pages: 102
Release: 2019-09-24
ISBN 10: 3030310000
ISBN 13: 9783030310004
Language: EN, FR, DE, ES & NL

Advancing Gene Fusion Detection Towards Personalized Cancer Nanodiagnostics Book Review:

This book presents a unique concept of merging nanotechnology and novel urinary biomarkers for accurate early prostate cancer detection, discussing an entire progressive pipeline of innovative new strategies in biosensor development, from a simple colorimetric system to a complex system for simultaneous multiple biomarker sensing. For newcomers to the field of nucleic acid biosensing, it also describes various isothermal amplification and amplification-free strategies, which are currently the main research areas. Lastly, the book introduces and demonstrates the notion of clinical nanobiosensor validation toward clinical translation: the ultimate aim of researchers in the biosensor field. This book is a valuable reference resource learners seeking inspiration for cancer biosensor development.

Principles of Surface Enhanced Raman Spectroscopy

Principles of Surface Enhanced Raman Spectroscopy
Author: Eric Le Ru,Pablo Etchegoin
Publsiher: Elsevier
Total Pages: 688
Release: 2008-11-17
ISBN 10: 9780080931555
ISBN 13: 0080931553
Language: EN, FR, DE, ES & NL

Principles of Surface Enhanced Raman Spectroscopy Book Review:

SERS was discovered in the 1970s and has since grown enormously in breadth, depth, and understanding. One of the major characteristics of SERS is its interdisciplinary nature: it lies at the boundary between physics, chemistry, colloid science, plasmonics, nanotechnology, and biology. By their very nature, it is impossible to find a textbook that will summarize the principles needed for SERS of these rather dissimilar and disconnected topics. Although a basic understanding of these topics is necessary for research projects in SERS with all its many aspects and applications, they are seldom touched upon as a coherent unit during most undergraduate studies in physics or chemistry. This book intends to fill this existing gap in the literature. It provides an overview of the underlying principles of SERS, from the fundamental understanding of the effect to its potential applications. It is aimed primarily at newcomers to the field, graduate students, researchers or scientists, attracted by the many applications of SERS and plasmonics or its basic science. The emphasis is on concepts and background material for SERS, such as Raman spectroscopy, the physics of plasmons, or colloid science, all of them introduced within the context of SERS, and from where the more specialized literature can be followed. Represents one of very few books fully dedicated to the topic of surface-enhanced Raman spectroscopy (SERS) Gives a comprehensive summary of the underlying physical concepts around SERS Provides a detailed analysis of plasmons and plasmonics