Separation Methods In Proteomics

Separation Methods In Proteomics
Author: Gary B. Smejkal,Alexander Lazarev
Publsiher: CRC Press
Total Pages: 536
Release: 2005-12-12
ISBN 10: 1420028057
ISBN 13: 9781420028058
Language: EN, FR, DE, ES & NL

Separation Methods In Proteomics Book Review:

Driven by the widespread growth of proteomic practices, protein separation techniques have been refined to minimize variability, optimize particular applications, and adapt to user preferences in the analysis of proteins. Separation Methods in Proteomics provides a comprehensive examination of all major separation techniques for proteomics research. Written as a compilation of hands-on methods exemplified by the work of several recognized leaders in the field, this book may serve as a guide for selection of the optimal separation strategies to solve particular biological problems. Recent progress in the development of robust analytical techniques and instrumentation has created the need for good quality biological samples that are subject to analysis. Emphasizing the importance of sample preparation, the book explains how proteomes can be divided into smaller, less complicated “subproteomes" for individual analysis. It also highlights several hybrid approaches that take into account protein interactions. Including applications of the separation methods currently employed in proteomic analyses for both clinical and basic research, Separation Methods in Proteomics contains practical information that can enhance the current and future endeavors of scientists in proteomics, genomics, transcriptomics, biomarker discovery, and drug discovery.

Handbook of Isoelectric Focusing and Proteomics

Handbook of Isoelectric Focusing and Proteomics
Author: David Garfin,Satinder Ahuja
Publsiher: Academic Press
Total Pages: 334
Release: 2005-05-23
ISBN 10: 9780120887521
ISBN 13: 0120887525
Language: EN, FR, DE, ES & NL

Handbook of Isoelectric Focusing and Proteomics Book Review:

Isoelectric focusing (IEF) is a high-resolution, stand-alone technique that can be used as an analytical method or tool for protein purification. The only current book on the market, the Handbook of Isoelectric Focusing and Proteomics is the ideal 'one-stop' source for germane information in this discipline. This highly practical book also contains chapters on alternative methods that may pave the way in the search for efficient techniques for fractionating and purifying proteins. Complete with the history of IEF focusing to authors' insights and practical tips, this book is a must for anyone working in proteomics. * Is the only current book available on the subject * Includes author insights and practical tips * Is an ideal single source for students and researchers working in proteomics

Introducing Proteomics

Introducing Proteomics
Author: Josip Lovric
Publsiher: John Wiley & Sons
Total Pages: 296
Release: 2011-06-17
ISBN 10: 1119957192
ISBN 13: 9781119957195
Language: EN, FR, DE, ES & NL

Introducing Proteomics Book Review:

Introducing Proteomics gives a concise and coherent overview of every aspect of current proteomics technology, which is a rapidly developing field that is having a major impact within the life and medical sciences. This student-friendly book, based on a successful course developed by the author, provides its readers with sufficient theoretical background to be able to plan, prepare, and analyze a proteomics study. The text covers the following: Separation Technologies Analysis of Peptides/Proteins by Mass Spectrometry Strategies in Proteomics This contemporary text also includes numerous examples and explanations for why particular strategies are better than others for certain applications. In addition, Introducing Proteomics includes extensive references and a list of relevant proteomics information sources; essential for any student. This no-nonsense approach to the subject tells students exactly what they need to know, leaving out unnecessary information. The student companion site enhances learning and provides answers to the end of chapter problems. "I think this book will be a popular and valuable resource for students and newcomers to the field who would like to have an overview and initial understanding of what proteomics is about. The contents are well organized and address the major issues." —Professor Walter Kolch, Director, Systems Biology Ireland & Conway Institute, University College Dublin Companion Website www.wiley.com/go/lovric

Proteomics Today

Proteomics Today
Author: Mahmoud H. Hamdan,Pier G. Righetti
Publsiher: John Wiley & Sons
Total Pages: 448
Release: 2005-05-13
ISBN 10: 0471709107
ISBN 13: 9780471709107
Language: EN, FR, DE, ES & NL

Proteomics Today Book Review:

The last few years have seen an unprecedented drive toward theapplication of proteomics to resolving challenging biomedical andbiochemical tasks. Separation techniques combined with modern massspectrometry are playing a central role in this drive. This bookdiscusses the increasingly important role of mass spectrometry inproteomic research, and emphasizes recent advances in the existingtechnology and describes the advantages and pitfalls as well. * Provides a scientifically valid method for analyzing theapproximatey 500,000 proteins that are encoded in the humangenome * Explains the hows and whys of using mass spectrometry inproteomic analysis * Brings together the latest approaches combining separationtechniques and mass spectrometry and their application in proteomeanalysis * Comments on future challenges and how they may be addressed * Includes sections on troubleshooting

Proteome Characterization and Proteomics

Proteome Characterization and Proteomics
Author: Timothy D. Veenstra,Richard D. Smith
Publsiher: Academic Press
Total Pages: 413
Release: 2003-10-01
ISBN 10: 9780080569154
ISBN 13: 0080569153
Language: EN, FR, DE, ES & NL

Proteome Characterization and Proteomics Book Review:

The content of this volume is designed to reach a wide audience, including those involved with relevant technologies such as electrophoresis and mass spectrometry, to those interested in how proteomics can benefit research. A wide range of techniques are discussed, each specifically designed to address different needs in proteomic analysis. The concluding chapter discusses the important issue related to handling large amounts of data accumulated in proteomic studies. Discusses proteomics in the postgenomic age Includes various strategies for quantitative proteomics Covers the role of MS in structural functional proteomics and proteomics in drug discovery and bioinformatics

Monolithic Silicas in Separation Science

Monolithic Silicas in Separation Science
Author: Klaus K. Unger,Nobuo Tanaka,Egidijus Machtejevas
Publsiher: John Wiley & Sons
Total Pages: 362
Release: 2010-11-29
ISBN 10: 352763326X
ISBN 13: 9783527633265
Language: EN, FR, DE, ES & NL

Monolithic Silicas in Separation Science Book Review:

Edited by the experts and pioneers in the field, this is the first monograph to cover the topic, containing the must-have information hitherto only scattered among journals. Clearly divided into sections on preparation, characterization and modeling, and applications, this is essential reading for chemists, chromatographers, analytical chemists, biochemists and biologists.

Proteomics of Human Body Fluids

Proteomics of Human Body Fluids
Author: Visith Thongboonkerd
Publsiher: Springer Science & Business Media
Total Pages: 533
Release: 2008-01-23
ISBN 10: 9781597454322
ISBN 13: 159745432X
Language: EN, FR, DE, ES & NL

Proteomics of Human Body Fluids Book Review:

This volume is the first collection of applications of proteomics to analyze various human body fluids. Proteomics of Human Bodyfluids consists of two parts. The first provides basic principles and strategies for proteomic analysis of human body fluids. The second offers more details regarding methodologies and recent findings and clinical applications of each specific type of human body fluids.

Monolithic Silicas in Separation Science

Monolithic Silicas in Separation Science
Author: Klaus K. Unger,Nobuo Tanaka,Egidijus Machtejevas
Publsiher: John Wiley & Sons
Total Pages: 362
Release: 2010-11-29
ISBN 10: 352763326X
ISBN 13: 9783527633265
Language: EN, FR, DE, ES & NL

Monolithic Silicas in Separation Science Book Review:

Edited by the experts and pioneers in the field, this is the first monograph to cover the topic, containing the must-have information hitherto only scattered among journals. Clearly divided into sections on preparation, characterization and modeling, and applications, this is essential reading for chemists, chromatographers, analytical chemists, biochemists and biologists.

Proteomics: Biomedical and Pharmaceutical Applications

Proteomics: Biomedical and Pharmaceutical Applications
Author: Hubert Hondermarck
Publsiher: Springer Science & Business Media
Total Pages: 396
Release: 2007-05-08
ISBN 10: 1402023235
ISBN 13: 9781402023231
Language: EN, FR, DE, ES & NL

Proteomics: Biomedical and Pharmaceutical Applications Book Review:

Human biology has now entered into a phase of post-genomics and it might not be an exaggeration to say that the major outcome of the human genome sequencing has finally been to open the way to the exploration of the proteome-proteomics. Proteins are the functional output of genes and there are two main expected outcomes from human proteomics. The first is to discover new molecular markers for early diagnosis and profiling of pathologies. The second is to decipher the intracellular signaling pathways leading to the initiation and progression of pathologies, for the identification of new targets and the development of innovative therapeutic strategies. This is clearly a promising challenge that this book explores through a series of ongoing experiences and projects representative of the new era in which biology and medicine have now entered.

Low-Abundance Proteome Discovery

Low-Abundance Proteome Discovery
Author: Egisto Boschetti,Pier Giorgio Righetti
Publsiher: Newnes
Total Pages: 364
Release: 2013-03-26
ISBN 10: 0124045960
ISBN 13: 9780124045965
Language: EN, FR, DE, ES & NL

Low-Abundance Proteome Discovery Book Review:

Low-Abundance Proteome Discovery addresses the most critical challenge in biomarker discovery and progress: the identification of low-abundance proteins. The book describes an original strategy developed by the authors that permits the detection of protein species typically found in very low abundance and that may yield valuable clues to future discoveries. Known as combinatorial peptide ligand libraries, these new methodologies are one of the hottest topics related to the study of proteomics and have applications in medical diagnostics, food quality, and plant analysis. The book is written for university and industry scientists starting proteomic studies of complex matrices (e.g., biological fluids, biopsies, recalcitrant plant tissues, foodstuff, and beverage analysis), researchers doing wet chemistry, and graduate-level students in the areas of analytical and biochemistry, biology, and genetics. Covers methodologies for enhancing the visibility of low-abundance proteins which, until now, has been the biggest challenge in biomarker progress Includes detailed protocols that address real-life needs in laboratory practice Addresses all applications, including human disease, food and beverage safety, and the discovery of new proteins/peptides of importance in nutraceutics Compiles the research and analytic protocols of the two scientists who are credited with the discovery of these landmark methodologies, also known as combinatorial peptide ligand libraries, for the identification of low-abundance proteins

Design and Synthesis of Advanced Materials for Separation Science

Design and Synthesis of Advanced Materials for Separation Science
Author: Michael Douglas Slater
Publsiher: Anonim
Total Pages: 380
Release: 2009
ISBN 10:
ISBN 13: UCAL:C3511321
Language: EN, FR, DE, ES & NL

Design and Synthesis of Advanced Materials for Separation Science Book Review:

Proteomics and Peptidomics

Proteomics and Peptidomics
Author: Gyorgy Marko-Varga
Publsiher: Elsevier
Total Pages: 632
Release: 2005
ISBN 10: 044451810X
ISBN 13: 9780444518101
Language: EN, FR, DE, ES & NL

Proteomics and Peptidomics Book Review:

Proteomics and peptidomics is the detailed understanding of the role that proteins and peptides play in health and disease and is a necessary compliment to genetic analysis. The functional expression analysis of both proteins and peptides plays a central role in modern drug discovery as well as drug development, and is also a key research area in systems biology.Proteomics and Peptidomics captures the width as well as the depth within the area and exemplifies the variety as well as the traditional basis of analytical chemistry that is needed in order to move forward in expression analysis studies. As a fast emerging field, it gives and overview of parts within the field combined with highly specialized and dedicated topics that are intended to compliment each other.

Separation Methods In Proteomics

Separation Methods In Proteomics
Author: Gary B. Smejkal,Alexander Lazarev
Publsiher: CRC Press
Total Pages: 536
Release: 2005-12-12
ISBN 10: 1420028057
ISBN 13: 9781420028058
Language: EN, FR, DE, ES & NL

Separation Methods In Proteomics Book Review:

Driven by the widespread growth of proteomic practices, protein separation techniques have been refined to minimize variability, optimize particular applications, and adapt to user preferences in the analysis of proteins. Separation Methods in Proteomics provides a comprehensive examination of all major separation techniques for proteomics research. Written as a compilation of hands-on methods exemplified by the work of several recognized leaders in the field, this book may serve as a guide for selection of the optimal separation strategies to solve particular biological problems. Recent progress in the development of robust analytical techniques and instrumentation has created the need for good quality biological samples that are subject to analysis. Emphasizing the importance of sample preparation, the book explains how proteomes can be divided into smaller, less complicated “subproteomes" for individual analysis. It also highlights several hybrid approaches that take into account protein interactions. Including applications of the separation methods currently employed in proteomic analyses for both clinical and basic research, Separation Methods in Proteomics contains practical information that can enhance the current and future endeavors of scientists in proteomics, genomics, transcriptomics, biomarker discovery, and drug discovery.

Encyclopedia of Separation Science

Encyclopedia of Separation Science
Author: Michael Cooke,C. F. Poole
Publsiher: Anonim
Total Pages: 4954
Release: 2000
ISBN 10:
ISBN 13: UOM:39015043253445
Language: EN, FR, DE, ES & NL

Encyclopedia of Separation Science Book Review:

A Century of Separation Science

A Century of Separation Science
Author: Haleem J. Issaq
Publsiher: CRC Press
Total Pages: 776
Release: 2001-12-19
ISBN 10: 9780824705763
ISBN 13: 0824705769
Language: EN, FR, DE, ES & NL

A Century of Separation Science Book Review:

A Century of Separation Science presents an extensive overview of the critical developments in separation science since 1900, covering recent advances in chromatography, electrophoresis, field-flow fractionation, countercurrent chromatography, and supercritical fluid chromatography for high-speed and high-throughput analysis.

The Evolution from Protein Chemistry to Proteomics

The Evolution from Protein Chemistry to Proteomics
Author: Roger L. Lundblad
Publsiher: CRC Press
Total Pages: 312
Release: 2005-10-14
ISBN 10: 1420036408
ISBN 13: 9781420036404
Language: EN, FR, DE, ES & NL

The Evolution from Protein Chemistry to Proteomics Book Review:

Largely driven by major improvements in the analytical capability of mass spectrometry, proteomics is being applied to broader areas of experimental biology, ranging from oncology research to plant biology to environmental health. However, while it has already eclipsed solution protein chemistry as a discipline, it is still essentially an extension

Proteomics

Proteomics
Author: Stephen R. Pennington,Michael J. Dunn
Publsiher: Garland Science
Total Pages: 313
Release: 2001
ISBN 10: 9781859962961
ISBN 13: 1859962963
Language: EN, FR, DE, ES & NL

Proteomics Book Review:

Proteomics: from protein sequence to function will appeal to undergraduates in biochemistry, molecular biology and genetics and all postgraduates and researchers with an interest in genomics and proteomics.

Clinical Proteomics

Clinical Proteomics
Author: Jennifer E. Van Eyk,Michael J. Dunn
Publsiher: Wiley-Blackwell
Total Pages: 659
Release: 2008-01-14
ISBN 10:
ISBN 13: UOM:39015073909429
Language: EN, FR, DE, ES & NL

Clinical Proteomics Book Review:

Unparalleled in its scope and depth, this book brings together proteomic approaches in diagnosis and treatment from all clinical fields, including clinical toxicology. The result is a new discipline in molecular medicine that will revolutionize the treatment and prevention of cancer, stroke and other severe diseases. Following an overview of clinical proteomics, the authors look at the technologies available, before moving on to cancer, cardiopulmonary disease, diabetes and stroke. A whole section is devoted to toxicity and the work is rounded off with a discussion of the future of clinical proteomics.

Immobilized PH Gradients

Immobilized PH Gradients
Author: P. G. Righetti
Publsiher: Elsevier
Total Pages: 397
Release: 1990
ISBN 10: 0444813012
ISBN 13: 9780444813015
Language: EN, FR, DE, ES & NL

Immobilized PH Gradients Book Review:

Immobilized pH gradients (IPG) represent the most advanced development of isoelectric focusing (IEF). Originally developed to overcome all the problems of IEF in soluble amphoteric buffers (CA) (such as pH gradient instability, complexation with CA chemicals, unreproducibility of pH gradients, protein precipitation at the pI), it turned out to be an entirely new technique, quite different in principle and operation from conventional IEF. The book is thus meant to bring the reader up to date with this fast developing field. The book is divided into six chapters containing information on: detailed treatment of all the chemistry of the Immobiline chemicals; theory of pH gradient generation (computer simulations, tables with all the possible pH recipes); all analytical aspects of IPGs, including staining techniques, blotting etc.; two-dimensional maps, with a detailed treatise of advantages and limitations; preparative aspects of IPGs, including comparison with other preparative electrophoretic techniques; some examples of applications, including genetic and forensic analysis, blood polymorphism etc. The book is extensive and up-to-date, while also extensively covering the theory.

Proteomics in Functional Genomics

Proteomics in Functional Genomics
Author: P. Jolles,Hans Jörnvall
Publsiher: Birkhäuser
Total Pages: 236
Release: 2013-03-11
ISBN 10: 3034884583
ISBN 13: 9783034884587
Language: EN, FR, DE, ES & NL

Proteomics in Functional Genomics Book Review:

A wealth of information has accumulated over the last few years on the human genome. The new insights have completely changed the focus of protein analysis. It is no longer time-consuming analysis of unknown products, but rather selective identifications of individual forms, modifications and processings, and overall analysis of global protein outputs from cells and tissues in health and disease. This book gears to the rising need of sensitive, accurate, and fast separation and identification techniques in proteomics. It discusses current methodologies of modern protein analysis, from isolation and sample preparation, over analysis and identification, to final characterization. Several evaluations concentrate on the now productive approaches of two-dimensional gel electrophoresis and mass spectrometry, but alternative methods and further perspectives are also outlined. The book includes an overlook over current databases to connect protein analysis data with all available information,...