Scientific Principles of Adipose Stem Cells

Scientific Principles of Adipose Stem Cells
Author: Lauren Elizabeth Kokai,Kacey Gribbin Marra,J. Peter Rubin
Publsiher: Academic Press
Total Pages: 350
Release: 2020-12-03
ISBN 10: 0128193778
ISBN 13: 9780128193778
Language: EN, FR, DE, ES & NL

Scientific Principles of Adipose Stem Cells Book Review:

Scientific Principles of Adipose Stem Cells provides readers with in-depth and expert knowledge on adipose stem cells, their developmental biologic origins, foundational research on ASC signaling mechanisms and immunomodulatory properties, and clinical insights into applications in regenerative medicine. Topics covered include basic adipose stem cell developmental biology and mechanisms of regulating self-renewal and activation in the stem cell niche, important methods for isolation and characterizing ASCs, and data on the impact on human demographics (age, sex, BMI) on ASC phenotype. A section devoted to ASC biology, ASCs for stem cell therapy and regenerative medicine, and ASCs in tissue engineering applications are also included. The book is written for scientists and clinicians who are broadly familiar with stem cells and basic cell biology principles and those seeking advanced information on adipose stem cells. Coverage of basic adipose stem cell developmental biology (maturation process during embryogenesis) and mechanisms of regulating self-renewal and activation in the stem cell niche Includes important methods for isolation and characterizing ASCs, as well as known data any impact of human demographics (age, sex, BMI) on ASC phenotype An entire section dedicated to ASC biology, additional sections will be devoted to ASCs for stem cell therapy and regenerative medicine, as well as ASCs in tissue engineering applications

Adipose Stem Cells and Regenerative Medicine

Adipose Stem Cells and Regenerative Medicine
Author: Yves-Gerard Illouz,Aris Sterodimas
Publsiher: Springer Science & Business Media
Total Pages: 278
Release: 2011-09-07
ISBN 10: 9783642200120
ISBN 13: 3642200125
Language: EN, FR, DE, ES & NL

Adipose Stem Cells and Regenerative Medicine Book Review:

The therapeutic potential of the use of adipose stem cells in regenerative medicine has been increasingly recognized, and in recent years concrete clinical benefits have accrued as these cells have been explored for a variety of applications. This readable and informative textbook tracks the progress that has been made in this fascinating new area of biomedicine. All aspects of the subject are considered, with particular attention to adipose cell biology, adipose tissue engineering strategies, and the diverse clinical applications of adipose stem cells. Funding issues, industrial approaches, regulatory challenges, and future directions are also examined. The two editors have vast experience in the field and have chosen leading experts from different countries to write on each topic. This book will excite the interest of all researchers, clinicians, and students wishing to gain an in-depth understanding of adipose stem cells and their flourishing role in regenerative medicine.

Stem Cells in Clinical Practice and Tissue Engineering

Stem Cells in Clinical Practice and Tissue Engineering
Author: Rakesh Sharma
Publsiher: BoD – Books on Demand
Total Pages: 352
Release: 2018-05-02
ISBN 10: 1789230101
ISBN 13: 9781789230109
Language: EN, FR, DE, ES & NL

Stem Cells in Clinical Practice and Tissue Engineering Book Review:

Stem Cells in Clinical Practice and Tissue Engineering is a concise book on applied methods of stem cell differentiation and optimization using tissue engineering methods. These methods offer immediate use in clinical regenerative medicine. The present volume will serve the purpose of applied stem cell differentiation optimization methods in clinical research projects, as well as be useful to relatively experienced stem cell scientists and clinicians who might wish to develop their stem cell clinical centers or research labs further. Chapters are arranged in the order of basic concepts of stem cell differentiation, clinical applications of pluripotent stem cells in skin, cardiac, bone, dental, obesity centers, followed by tissue engineering, new materials used, and overall evaluation with their permitted legal status.

Adipose-Derived Stem Cells

Adipose-Derived Stem Cells
Author: Jeffrey M. Gimble,Bruce A. Bunnell
Publsiher: Humana Press
Total Pages: 474
Release: 2010-11-19
ISBN 10: 9781617379598
ISBN 13: 161737959X
Language: EN, FR, DE, ES & NL

Adipose-Derived Stem Cells Book Review:

During the past decade, a wide range of scientific disciplines have adopted the use of adipose-derived stem/stromal cells (ASCs) as an important tool for research and discovery. In Adipose-Derived Stem Cells: Methods and Protocols, experts from the field, including members of the esteemed International Federation of Adipose Therapeutics and Science (IFATS), provide defined and established protocols in order to further codify the utilization of these powerful and accessible cells. With chapters organized around approaches spanning the discovery, pre-clinical, and clinical processes, much of the emphasis is placed on human ASC, while additional techniques involving small and large animal species are included. As a volume in the highly successful Methods in Molecular BiologyTM series, the detailed contributions include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and notes on troubleshooting and avoiding known pitfalls. Comprehensive and cutting-edge, Adipose-Derived Stem Cells: Methods and Protocols serves as a vital reference text for experienced researchers as well as new students on the path to further exploring the incredible potential of ASCs.

Greenfield's Surgery

Greenfield's Surgery
Author: Michael W. Mulholland
Publsiher: Lippincott Williams & Wilkins
Total Pages: 2090
Release: 2016-11-15
ISBN 10: 146989002X
ISBN 13: 9781469890029
Language: EN, FR, DE, ES & NL

Greenfield's Surgery Book Review:

Revised, updated, and enhanced from cover to cover, the Sixth Edition of Greenfield’s Surgery: Scientific Principles and Practice remains the gold standard text in the field of surgery. It reflects surgery’s rapid changes, new technologies, and innovative techniques, integrating new scientific knowledge with evolving changes in surgical care. Updates to this edition include new editors and contributors, and a greatly enhanced visual presentation. Balancing scientific advances with clinical practice, Greenfield’s Surgery is an invaluable resource for today’s residents and practicing surgeons.

Biobanking and Cryopreservation of Stem Cells

Biobanking and Cryopreservation of Stem Cells
Author: Feridoun Karimi-Busheri,Michael Weinfeld
Publsiher: Springer
Total Pages: 238
Release: 2016-11-10
ISBN 10: 3319454579
ISBN 13: 9783319454573
Language: EN, FR, DE, ES & NL

Biobanking and Cryopreservation of Stem Cells Book Review:

Biobanking is considered to be one of the ten ideas changing the world with an estimated value of $45 billion by 2025. Despite the challenges, as the climate for innovation in the biobanking industry continues to flourish around the world, it is certain that amazing discoveries will emerge from this large-scale method of preserving and accessing human samples; biobanking is no longer just a place for collecting and storing samples. This book will cover a wide variety of subjects from across the future biobanking spectrum including scientific strategies, personalized medicine, regenerative medicine and stem cell challenges, disease surveillance, population genetics and innovative methods of biobanking.

Principles of Regenerative Medicine

Principles of Regenerative Medicine
Author: Anthony Atala,Robert Lanza,Tony Mikos,Robert Nerem
Publsiher: Academic Press
Total Pages: 1454
Release: 2018-08-09
ISBN 10: 0128098937
ISBN 13: 9780128098936
Language: EN, FR, DE, ES & NL

Principles of Regenerative Medicine Book Review:

Principles of Regenerative Medicine, Third Edition, details the technologies and advances applied in recent years to strategies for healing and generating tissue. Contributions from a stellar cast of researchers cover the biological and molecular basis of regenerative medicine, highlighting stem cells, wound healing and cell and tissue development. Advances in cell and tissue therapy, including replacement of tissues and organs damaged by disease and previously untreatable conditions, such as diabetes, heart disease, liver disease and renal failure are also incorporated to provide a view to the future and framework for additional studies. Comprehensively covers the interdisciplinary field of regenerative medicine with contributions from leaders in tissue engineering, cell and developmental biology, biomaterials sciences, nanotechnology, physics, chemistry, bioengineering and surgery Includes new chapters devoted to iPS cells and other alternative sources for generating stem cells as written by the scientists who made the breakthroughs Edited by a world-renowned team to present a complete story of the development and promise of regenerative medicine

Progenitor and Stem Cell Technologies and Therapies

Progenitor and Stem Cell Technologies and Therapies
Author: Anthony Atala
Publsiher: Elsevier
Total Pages: 568
Release: 2012-03-15
ISBN 10: 0857096079
ISBN 13: 9780857096074
Language: EN, FR, DE, ES & NL

Progenitor and Stem Cell Technologies and Therapies Book Review:

Progenitor and stem cells have the ability to renew themselves and change into a variety of specialised types, making them ideal materials for therapy and regenerative medicine. Progenitor and stem cell technologies and therapies reviews the range of progenitor and stem cells available and their therapeutic application. Part one reviews basic principles for the culture of stem cells before discussing technologies for particular cell types. These include human embryonic, induced pluripotent, amniotic and placental, cord and multipotent stem cells. Part two discusses wider issues such as intellectual property, regulation and commercialisation of stem cell technologies and therapies. The final part of the book considers the therapeutic use of stem and progenitor cells. Chapters review the use of adipose tissue-derived stem cells, umbilical cord blood (UCB) stem cells, bone marrow, auditory and oral cavity stem cells. Other chapters cover the use of stem cells in therapies in various clinical areas, including lung, cartilage, urologic, nerve and cardiac repair. With its distinguished editor and international team of contributors, Progenitor and stem cell technologies and therapies is a standard reference for both those researching in cell and tissue biology and engineering as well as medical practitioners investigating the therapeutic use of this important technology. Reviews the range of progenitor and stem cells available and outlines their therapeutic application Examines the basic principles for the culture of stem cells before discussing technologies for particular cell types, including human embryonic, induced pluripotent, amniotic and placental, cord and multipotent stem cells Includes a discussion of wider issues such as intellectual property, regulation and commercialisation of stem cell technologies and therapies

Cells and Biomaterials in Regenerative Medicine

Cells and Biomaterials in Regenerative Medicine
Author: Daniel Eberli
Publsiher: BoD – Books on Demand
Total Pages: 384
Release: 2014-11-26
ISBN 10: 9535117319
ISBN 13: 9789535117315
Language: EN, FR, DE, ES & NL

Cells and Biomaterials in Regenerative Medicine Book Review:

This book serves as a good starting point for anyone interested in the application of tissue engineering. It offers a colorful mix of topics, which explain the obstacles and possible solutions for TE applications. The first part covers the use of adult stem cells and their applications. The following chapters offer an insight into the development of a tailored biomaterial for organ replacement and highlight the importance of cell-biomaterial interaction. In summary, this book offers insights into a wide variety of cells, biomaterials, interfaces and applications of the next generation biotechnology, which is tissue engineering.

Principles of Regenerative Medicine

Principles of Regenerative Medicine
Author: Anthony Atala,Robert Lanza,James A. Thomson,Robert Nerem
Publsiher: Academic Press
Total Pages: 1202
Release: 2010-12-16
ISBN 10: 9780123814234
ISBN 13: 0123814235
Language: EN, FR, DE, ES & NL

Principles of Regenerative Medicine Book Review:

Virtually any disease that results from malfunctioning, damaged, or failing tissues may be potentially cured through regenerative medicine therapies, by either regenerating the damaged tissues in vivo, or by growing the tissues and organs in vitro and implanting them into the patient. Principles of Regenerative Medicine discusses the latest advances in technology and medicine for replacing tissues and organs damaged by disease and of developing therapies for previously untreatable conditions, such as diabetes, heart disease, liver disease, and renal failure. Key for all researchers and instituions in Stem Cell Biology, Bioengineering, and Developmental Biology The first of its kind to offer an advanced understanding of the latest technologies in regenerative medicine New discoveries from leading researchers on restoration of diseased tissues and organs

Principles of Tissue Engineering

Principles of Tissue Engineering
Author: Robert Lanza,Robert Langer,Joseph P. Vacanti
Publsiher: Academic Press
Total Pages: 1936
Release: 2013-10-17
ISBN 10: 0123983703
ISBN 13: 9780123983701
Language: EN, FR, DE, ES & NL

Principles of Tissue Engineering Book Review:

Now in its fourth edition, Principles of Tissue Engineering has been the definite resource in the field of tissue engineering for more than a decade. The fourth edition provides an update on this rapidly progressing field, combining the prerequisites for a general understanding of tissue growth and development, the tools and theoretical information needed to design tissues and organs, as well as a presentation by the world’s experts of what is currently known about each specific organ system. As in previous editions, this book creates a comprehensive work that strikes a balance among the diversity of subjects that are related to tissue engineering, including biology, chemistry, material science, and engineering, among others, while also emphasizing those research areas that are likely to be of clinical value in the future. This edition includes greatly expanded focus on stem cells, including induced pluripotent stem (iPS) cells, stem cell niches, and blood components from stem cells. This research has already produced applications in disease modeling, toxicity testing, drug development, and clinical therapies. This up-to-date coverage of stem cell biology and other emerging technologies –such as brain-machine interfaces for controlling bionics and neuroprostheses– is complemented by a series of new and updated chapters on recent clinical experience in applying tissue engineering, as well as a new section on the application of tissue-engineering techniques for food production. The result is a comprehensive textbook that will be useful to students and experts alike. Includes new chapters on biomaterial-protein interactions, nanocomposite and three-dimensional scaffolds, skin substitutes, spinal cord, vision enhancement, and heart valves Offers expanded coverage of adult and embryonic stem cells of the cardiovascular, hematopoietic, musculoskeletal, nervous, and other organ systems Full-color presentation throughout

Regenerative Medicine and Plastic Surgery

Regenerative Medicine and Plastic Surgery
Author: Dominik Duscher,Melvin A. Shiffman
Publsiher: Springer Nature
Total Pages: 472
Release: 2019-11-27
ISBN 10: 3030199622
ISBN 13: 9783030199623
Language: EN, FR, DE, ES & NL

Regenerative Medicine and Plastic Surgery Book Review:

This book presents the latest advances in the field of regenerative medicine in plastic surgery. It is the first authoritative reference documenting all the ways that plastic surgical practice and regenerative medicine science overlap or provide a road map for the future of both specialties. The Editors have provided a valuable service by gathering in one place the leading voices in these two fields in clear and concise manner.The first part introduces readers to essential principles of skin and soft tissue regeneration, e.g. the possibility of using mesenchymal stem cells for wound healing. Since bone serves as a supportive tissue in most of the body, bone regeneration is an important aspect of regenerative medicine; accordingly, the second part discusses the novel bone implants, activated bone grafts and bone tissue engineering. The book’s third part, focusing on cartilage regeneration, includes chapters on e.g. stem cells and ear regeneration. In turn, part four addresses muscle and tendon regeneration: from tendon to bone and tendon to muscle, as well as aging in the realm of muscle regeneration. Lastly, part five highlights nerve regeneration, deepening surgeons’ knowledge to help them successfully treat injuries to the peripheral neural system. Written by leading experts this book is an invaluable resource for researchers, students, beginners and experienced clinicians in a range of specialties. "With beautiful clinical images and artwork, this book will be a central companion to both practicing plastic surgeons who wish to remain abreast of oncoming technologic advances and regenerative medicine researchers who wish to understand the current state of the art of surgical reconstruction." - Geoffrey C. Gurtner, MD, FACS Johnson and Johnson Distinguished Professor of Surgery Professor (by courtesy) of Bioengineering and Materials Science Inaugural Vice Chairman of Surgery for Innovation Stanford University School of Medicine

Essentials of Stem Cell Biology

Essentials of Stem Cell Biology
Author: Robert Lanza,John Gearhart,Brigid Hogan,Douglas Melton,Roger Pedersen,E. Donnall Thomas,James A. Thomson,Ian Sir Wilmut
Publsiher: Academic Press
Total Pages: 680
Release: 2009-06-05
ISBN 10: 9780080884974
ISBN 13: 0080884970
Language: EN, FR, DE, ES & NL

Essentials of Stem Cell Biology Book Review:

First developed as an accessible abridgement of the successful Handbook of Stem Cells, Essentials of Stem Cell Biology serves the needs of the evolving population of scientists, researchers, practitioners and students that are embracing the latest advances in stem cells. Representing the combined effort of seven editors and more than 200 scholars and scientists whose pioneering work has defined our understanding of stem cells, this book combines the prerequisites for a general understanding of adult and embryonic stem cells with a presentation by the world's experts of the latest research information about specific organ systems. From basic biology/mechanisms, early development, ectoderm, mesoderm, endoderm, methods to application of stem cells to specific human diseases, regulation and ethics, and patient perspectives, no topic in the field of stem cells is left uncovered. Selected for inclusion in Doody's Core Titles 2013, an essential collection development tool for health sciences libraries Contributions by Nobel Laureates and leading international investigators Includes two entirely new chapters devoted exclusively to induced pluripotent stem (iPS) cells written by the scientists who made the breakthrough Edited by a world-renowned author and researcher to present a complete story of stem cells in research, in application, and as the subject of political debate Presented in full color with glossary, highlighted terms, and bibliographic entries replacing references

Preservation of Cells

Preservation of Cells
Author: Allison Hubel
Publsiher: John Wiley & Sons
Total Pages: 216
Release: 2018-02-13
ISBN 10: 1118989848
ISBN 13: 9781118989845
Language: EN, FR, DE, ES & NL

Preservation of Cells Book Review:

Helps those that use cell preservation to develop new protocols or improve existing protocols This book provides readers with the tools needed to develop or debug a preservation protocol for cells. The core structure and content of the text grew from a professional short course that has been offered at the Biopreservation Core Resource for the last 10 years. This comprehensive text describes, step by step, the individual elements of a protocol, including the relevant scientific principles for each phase of the protocol. It can be used by anyone who is involved in cell preservation—even by those who are not experts in freezing of cells—because it provides the scientific basis for those that want to understand the basis for the protocol. Preservation of Cells: A Practical Manual begins by first introducing readers to the subject of preserving cells. It then goes on to cover Pre-freeze Processing and Characterization; Formulation and Introduction of Cryopreservation Solutions; Freezing Protocols; Storage and Shipping of Frozen Cells; Thawing and Post Thaw Processing; Post-thaw Assessment; and Algorithm-driven Protocol Optimization. Clearly explains the reasons behind every step in the development of a preservation protocol and the scientific principles behind them Provides alternative modes of preservation for when conventional methods of cryopreservation are not appropriate for a given cell type or application Enables more organization to achieve improved post thaw recoveries and process consistency Preservation of Cells: A Practical Manual is an important book for researchers, laboratory technicians and students in cell biology, stem cell biology, tissue engineering, and regenerative medicine. It is also useful to cell bankers, regenerative medicine, biomarker discovery or precision medicine companies, and cell therapy labs, blood bankers, biobankers, and biotechnology companies.

Stromal Cells

Stromal Cells
Author: Mani T. Valarmathi
Publsiher: BoD – Books on Demand
Total Pages: 260
Release: 2019-01-23
ISBN 10: 1789849845
ISBN 13: 9781789849844
Language: EN, FR, DE, ES & NL

Stromal Cells Book Review:

Stromal cells are connective tissue cells of any organ, and they support the function of the parenchymal cells of that particular organ. Stromal/stromal stem cells are fundamentally a heterogeneous population of cells with contradictory differentiation potential depending upon their environmental niche. Stromal cell biology is not only intriguing, but equally stromal cell ontogeny in vivo remains challenging. In recent years there has been substantial advances in our understanding of stromal cell biology, especially stromal cell isolation, characterization, differentiation, and interactions in physiological (epithelial-stromal interactions) as well as pathophysiological (stromal-cancer interactions) contexts. In addition, stromal cells are also utilized more and more as a therapeutic tool not only in the field of gene therapy but also in the translational field of tissue engineering and regenerative medicine. Therefore, the goal of this book is to consolidate the recent advances in the area of stromal/stromal stem cell biology covering a broad range of interrelated topics in a timely fashion and to disseminate that knowledge in a lucid way to a greater scientific audience. This book will prove highly useful for students, researchers, and clinicians in stem cell biology, developmental biology, cancer biology, pathology, oncology, as well as tissue engineering and regenerative medicine. This quick reference will benefit anyone desiring a thorough overview of stromal cell structure, function, and its therapeutic implications.

Principles of Tissue Engineering

Principles of Tissue Engineering
Author: Robert Lanza,Robert Langer,Joseph P. Vacanti
Publsiher: Elsevier
Total Pages: 995
Release: 2000-05-16
ISBN 10: 008053967X
ISBN 13: 9780080539676
Language: EN, FR, DE, ES & NL

Principles of Tissue Engineering Book Review:

The opportunity that tissue engineering provides for medicine is extraordinary. In the United States alone, over half-a-trillion dollars are spent each year to care for patients who suffer from tissue loss or dysfunction. Although numerous books and reviews have been written on tissue engineering, none has been as comprehensive in its defining of the field. Principles of Tissue Engineering combines in one volume the prerequisites for a general understanding of tissue growth and development, the tools and theoretical information needed to design tissues and organs, as well as a presentation of applications of tissue engineering to diseases affecting specific organ systems. The first edition of the book, published in 1997, is the definite reference in the field. Since that time, however, the discipline has grown tremendously, and few experts would have been able to predict the explosion in our knowledge of gene expression, cell growth and differentiation, the variety of stem cells, new polymers and materials that are now available, or even the successful introduction of the first tissue-engineered products into the marketplace. There was a need for a new edition, and this need has been met with a product that defines and captures the sense of excitement, understanding and anticipation that has followed from the evolution of this fascinating and important field. Key Features * Provides vast, detailed analysis of research on all of the major systems of the human body, e.g., skin, muscle, cardiovascular, hematopoietic, and nerves * Essential to anyone working in the field * Educates and directs both the novice and advanced researcher * Provides vast, detailed analysis of research with all of the major systems of the human body, e.g. skin, muscle, cardiovascular, hematopoietic, and nerves * Has new chapters written by leaders in the latest areas of research, such as fetal tissue engineering and the universal cell * Considered the definitive reference in the field * List of contributors reads like a "who's who" of tissue engineering, and includes Robert Langer, Joseph Vacanti, Charles Vacanti, Robert Nerem, A. Hari Reddi, Gail Naughton, George Whitesides, Doug Lauffenburger, and Eugene Bell, among others

Stem Cell and Gene Therapy for Cardiovascular Disease

Stem Cell and Gene Therapy for Cardiovascular Disease
Author: Emerson C. Perin,Leslie W. Miller,Doris Taylor,James T. Willerson
Publsiher: Academic Press
Total Pages: 538
Release: 2015-08-21
ISBN 10: 0128018631
ISBN 13: 9780128018637
Language: EN, FR, DE, ES & NL

Stem Cell and Gene Therapy for Cardiovascular Disease Book Review:

Stem Cell and Gene Therapy for Cardiovascular Disease is a state-of-the-art reference that combines, in one place, the breadth and depth of information available on the topic. As stem cell and gene therapies are the most cutting-edge therapies currently available for patients with heart failure, each section of the book provides information on medical trials from contributors and specialists from around the world, including not only what has been completed, but also what is planned for future research and trials. Cardiology researchers, basic science clinicians, fellows, residents, students, and industry professionals will find this book an invaluable resource for further study on the topic. Provides information on stem and gene therapy medical trials from contributors and specialists around the world, including not only what has been completed, but also what is planned for future research and trials Presents topics that can be applied to allogeneic cells, mesenchymal cells, gene therapy, cardiomyoctyes, iPS cells, MAPC's, and organogenesis Covers the three areas with the greatest clinical trials to date: chronic limb ischemia, chronic angina, and acute MI Covers the prevailing opinions on how to harness the body’s natural repair mechanisms Ideal resource for cardiology researchers, basic science clinicians, fellows, residents, students, and industry professionals

A Roadmap to Nonhematopoietic Stem Cell-Based Therapeutics

A Roadmap to Nonhematopoietic Stem Cell-Based Therapeutics
Author: Xiao-Dong Chen
Publsiher: Academic Press
Total Pages: 544
Release: 2018-08-31
ISBN 10: 0128119217
ISBN 13: 9780128119211
Language: EN, FR, DE, ES & NL

A Roadmap to Nonhematopoietic Stem Cell-Based Therapeutics Book Review:

A Roadmap to Non-hematopoietic Stem Cell-Based Therapeutics: From the Bench to the Clinic is a resource that provides an overview of the principles of stem cell therapy, the promises and challenges of using stem cells for treating various clinical conditions, and future perspectives. The overall goal is to facilitate the translation of basic research on stem cells to clinical applications. The properties of stem cells from various sources are reviewed and the advantages and disadvantages of each for clinical use are discussed. Modifying stem cell properties through preconditioning strategies using physical, chemical, genetic, and molecular manipulation to improve cell survival, increase cell differentiation potential, enhance production of paracrine factors, and facilitate homing to the site of injury or disease upon transplantation are reviewed. Various routes of stem cell administration and dosing, and the duration of effects, are explored. Individual chapters are written by experts in the field and focus on the use of stem cells in treating various degenerative diseases, autoimmune diseases, wound healing, cardiovascular disease, spinal cord injury, oral and dental diseases, and skeletal disorders. Finally, experts in the regulatory arena discuss mechanisms used in different countries for approving the use of stem cells to treat diseases and many common issues that are typically encountered while seeking approval for this class of therapeutic agent. Offers advanced students, as well as new researchers, an overview of the principles of stem cell therapy Discusses a wide array of pressing clinical issues with stem cell-based therapies so that new ideas in the laboratory can be efficiently translated to the clinic through better designed clinical trials Helps clarify current regulatory mechanisms so that the safe use of stem cells for treating a variety of diseases can move forward Fosters cross-disciplinary dialogue between research scientists and physicians to accelerate the safe implementation of efficacious cell therapies

Pluripotent Stem Cells

Pluripotent Stem Cells
Author: Deepa Bhartiya,Nibedita Lenka
Publsiher: BoD – Books on Demand
Total Pages: 640
Release: 2013-08-28
ISBN 10: 9535111922
ISBN 13: 9789535111924
Language: EN, FR, DE, ES & NL

Pluripotent Stem Cells Book Review:

Stem cells have generated a lot of excitement among the researchers, clinicians and the public alike. Various types of stem cells are being evaluated for their regenerative potential. Marginal benefit resulting by transplanting autologus stem cells (deemed to be absolutely safe) in various clinical conditions has been proposed to be a growth factor effect rather than true regeneration. In contrast, various pre-clinical studies have been undertaken, using differentiated cells from embryonic stem cells or induced pluripotent stem cells have shown promise, functional improvement and no signs of teratoma formation. The scientists are not in a rush to reach the clinic but a handful of clinical studies have shown promise. This book is a collection of studies/reviews, beginning with an introduction to the pluripotent stem cells and covering various aspects like derivation, differentiation, ethics, etc., and hence would provide insight into the recent standing on the pluripotent stem cells biology. The chapters have been categorized into three sections, covering subjects ranging from the generation of pluripotent stem cells and various means of their derivation from embryonic as well as adult tissues, the mechanistic understanding of pluripotency and narrating the potential therapeutic implications of these in vitro generated cells in various diseases, in addition to the associated pros and cons in the same.

Stem Cell Biology

Stem Cell Biology
Author: Dr. Indumathi Somasundaram,Dr. Dhanasekaran Marappagounder,Dr. Pankaj Kaingade
Publsiher: Evincepub Publishing
Total Pages: 102
Release: 2020-01-18
ISBN 10: 9389774357
ISBN 13: 9789389774351
Language: EN, FR, DE, ES & NL

Stem Cell Biology Book Review:

Stem cell research and therapeutics has been captivating in recent decades due to its versatile discoveries on its potential to treat myriad of diseases. This is due to its properties of being undifferentiated, yet self-renews and differentiates into any type of cells, upon physiological signaling mechanisms. These sole attributes of stem cells, has created inquisitiveness in the minds of scientists and young researchers to explore every aspects of stem cells. This has opened a single doorway to the world of regenerative medicine, thereby saving millions of lives from wide diseases. Although stem cell is creating a new revolution in recent decades, due to its wider hypes and advancement in technologies, it is not becoming cost-effective for young generation University/college students to actually understand what stem cells are? Now-a-days, almost every life science course in College/ University either UG, PG or Specialized Diploma, has either a Unit on Stem cell or a full subject/paper on stem cell biology. Unfortunately, although learning about this new emerging field is imperative, academicians are unable to fulfill the stem cell practical due to the hype created about its tedious, costly coupled with advanced instrumentation facility. Thus, youngsters, being the future scientists are unaware about basic techniques of stem cell biology. Wide job opportunities are increasing day by day for youngsters in biotech industries, healthcare sectors, stem cell companies and banking sectors. Nevertheless, the students are unable to make the best use of these jobs, due to lack of basic know-how on stem cell biology or their basic laboratory techniques. This book is created to remove the bottleneck involved and help students to learn all the stem cell laboratory technique in a simple and easy fashion. We explain over here, the practical manual stem cell techniques that can be done with a basic culture laboratory set up. With such simple manual techniques coupled with shorter time and cost-effectiveness, students can understand all underlying principles and procedures involved in collection, isolation, enumeration, culturing, differentiation and in-vitro characterization of stem cells from various adult stem cell sources in a step-wise easy to understand manner. Although flowcytometry plays an important role in characterization of stem cells, due to cost of the machine, techniques of flowcytometry cannot be a part of lab manual in course of various Universities. However, to help the students, the authors are soon coming out with a new book on "Characterization of stem cells using flowcytometry: An easy Guide".