Psychiatric Genomics

Psychiatric Genomics
Author: Evangelia Eirini Tsermpini,Martin Alda,George P. Patrinos
Publsiher: Academic Press
Total Pages: 424
Release: 2020-12-15
ISBN 10: 9780128196021
ISBN 13: 0128196025
Language: EN, FR, DE, ES & NL

Psychiatric Genomics Book Review:

Psychiatric Genomics presents and synthesizes available knowledge in the field of psychiatric genomics, offering methodologies to advance new research and aid clinical translation. After providing an introduction to genomics and psychiatry, international experts discuss the genomic basis of schizophrenia, bipolar disorder, depression, personality disorders, anxiety disorders, addictions, eating disorders, and sleep disorders, among other disorders. In addition, recommendations for next steps in clinical implementation and drug discovery are discussed in-depth, with chapters dedicated to pharmacogenomics and antipsychotics, antidepressants and mood stabilizers, adverse drug reactions, implementation of pharmacogenomics in psychiatric clinics, and ethical issues. Finally, methods sections provide a solid grounding in research approaches and computational analytics, from using animal models in psychiatric genomics and accessing biobanks, to employing computational analysis, genome-wide association studies (GWAS), brain pathophysiology, and endophenotypes in psychiatric research. Thoroughly examines the genetic mechanisms underlying a broad range of psychiatric disorders Offers genomic methodologies and analytical approaches supporting new research and clinical translation, including personalized diagnosis and treatment models Features chapter contributions from international leaders in the field

Psychiatric Genomics

Psychiatric Genomics
Author: Evangelia Eirini Tsermpini,Martin Alda,George P. Patrinos
Publsiher: Academic Press
Total Pages: 424
Release: 2020-11-01
ISBN 10: 0128214007
ISBN 13: 9780128214008
Language: EN, FR, DE, ES & NL

Psychiatric Genomics Book Review:

Although psychiatric disorders affect a large percentage of the world population, current treatment approaches and drugs administered often come with unwelcome side effects that may decrease patients’ quality of life. Psychiatric genomics is a rapidly growing field that adopts computational approaches to identify genetic factors underlying psychiatric disorders, as well as the appropriate drug and dosage plans, to enhance personalized treatment and avoid adverse reactions. Psychiatric Genomics presents and synthesizes available knowledge in the field of psychiatric genomics, and offers methodologies to advance new research and aid clinical translation. After providing an introduction to genomics and psychiatry, across 23 chapters, international experts discuss the genomic basis of schizophrenia, bipolar disorder, depression, personality disorders, anxiety disorders, addictions, eating disorders, and sleep disorders, among other disorders. In addition, recommendations for next steps in clinical implementation and drug discovery are discussed in-depth, with chapters dedicated to pharmacogenomics and antipsychotics, antidepressants and mood stabilizers, adverse drug reactions, implementation of pharmacogenomics in psychiatric clinics, and ethical issues. Methods sections provide a solid grounding in research approaches and computational analytics, from using animal models in psychiatric genomics and accessing biobanks to employing computational analysis, genome-wide association studies (GWAS), brain pathophysiology, and endophenotypes in psychiatric research. Thoroughly examines genetic mechanisms underlying a broad range of psychiatric disorders Offers genomic methodologies and analytical approaches supporting new research and clinical translation, as well as personalized diagnosis and treatment models Features chapters contributions from international leaders in the field

Psychiatric Genetics

Psychiatric Genetics
Author: Thomas Schulze,Francis McMahon
Publsiher: Oxford University Press
Total Pages: 240
Release: 2018
ISBN 10: 0190221976
ISBN 13: 9780190221973
Language: EN, FR, DE, ES & NL

Psychiatric Genetics Book Review:

Psychiatrists and other mental health professionals are increasingly confronted with questions about the genetics of psychiatric illness, and the clinical applications of new genetic findings. Psychiatric Genetics: A Primer for Clinical and Basic Scientists addresses these questions through a straightforward introduction to the essentials of psychiatric genetics, complementing more comprehensive textbooks that may seem overwhelming for those new to the field. Written and edited by leaders in the field and the International Society of Psychiatric Genetics (ISPG), the book covers basic epidemiology, recruitment for human studies, phenotyping strategies, formal genetic and molecular genetic studies, statistical genetics, bioinformatics and genomics, pharmacogenetics, the most relevant animal models, and biobanking. Each chapter begins with a list of "take home" points that summarizes content, followed by a brief overview of current knowledge and suggestions for further reading. This Primer is ideal for medical students, psychiatric residents, psychiatrists, and basic neuroscience researchers who are interested in learning about the key concepts and recent advances in the exciting field of psychiatric genetics.

Psychiatric Genetics

Psychiatric Genetics
Author: Michael Arribas-Ayllon,Andrew Bartlett,Jamie Lewis
Publsiher: Routledge
Total Pages: 234
Release: 2019-02-13
ISBN 10: 1317329627
ISBN 13: 9781317329626
Language: EN, FR, DE, ES & NL

Psychiatric Genetics Book Review:

Psychiatric genetics has become ‘Big Biology’. This may come as a surprising development to those familiar with its controversial history. From eugenic origins and contentious twin studies to a global network of laboratories employing high-throughput genetic and genomic technologies, biological research on psychiatric disorders has become an international, multidisciplinary assemblage of massive data resources. How did psychiatric genetics achieve this scale? How is it socially and epistemically organized? And how do scientists experience this politics of scale? Psychiatric Genetics: From Hereditary Madness to Big Biology develops a sociological approach of exploring the origins of psychiatric genetics by tracing several distinct styles of scientific reasoning that coalesced at the beginning of the twentieth century. These styles of reasoning reveal, among other things, a range of practices that maintain an extraordinary stability in the face of radical criticism, internal tensions and scientific disappointments. The book draws on a variety of methods and materials to explore these claims. Combining genealogical analysis of historical literature, rhetorical analysis of scientific review articles, interviews with scientists, ethnographic observations of laboratory practices and international conferences, this book offers a comprehensive and detailed exploration of both local and global changes in the field of psychiatric genetics.

Psychiatric Genetics and Genomics

Psychiatric Genetics and Genomics
Author: Peter McGuffin,Michael J Owen,Irving I Gottesman
Publsiher: Oxford University Press
Total Pages: 492
Release: 2004-09-23
ISBN 10: 9780198564867
ISBN 13: 0198564864
Language: EN, FR, DE, ES & NL

Psychiatric Genetics and Genomics Book Review:

Genetics promises to provide one of the most powerful approaches to understanding the functional pathology of the human brain. This book starts with a brief introduction to the relevant molecular and cellular biology and then moves on to cover the evidence for a genetic contribution to normal and abnormal development and to abnormal behaviour in adult life. The final section covers counselling, ethics and takes a look to the future.

Psychiatric Genetics

Psychiatric Genetics
Author: Jordan W. Smoller,Beth Rosen Sheidley,Ming T. Tsuang
Publsiher: American Psychiatric Pub
Total Pages: 337
Release: 2009-02-20
ISBN 10: 1585628794
ISBN 13: 9781585628797
Language: EN, FR, DE, ES & NL

Psychiatric Genetics Book Review:

As more patients seek information about family risks of psychiatric illness -- an interest likely to increase as gene-identification studies are publicized -- most psychiatrists agree it is their role to discuss these issues but admit they are ill-prepared to do so. Psychiatric Genetics addresses that need as the first book to focus on clinical applications of genetics in psychiatry. It covers issues involved in genetic counseling, the interpretation of familial and genetic information for clinical use, information regarding risks associated with specific psychiatric disorders, risk/benefit considerations related to medication use during pregnancy, and the ethical and social implications of psychiatric genetic knowledge and research -- including the prospects for genetic testing. While other books have been written for the genetics community, this volume is addressed to practitioners: a clinically relevant resource that can help them understand the often bewildering flood of information about genetics -- information difficult to interpret, let alone integrate into practice -- and enable them to respond to patients' requests to predict the risk of recurrence of psychiatric illness or provide information about reproductive and pregnancy-related issues. Experts from psychiatry, genetic epidemiology, molecular genetics, genetic counseling, cognitive psychology, and ethics focus on issues that have received little attention elsewhere yet are of increasing importance to clinicians. Written at a level that assumes no particular expertise in genetics, the book features these immediately applicable benefits: It offers a framework for understanding and critically evaluating the psychiatric genetic research literature, enabling clinicians to better understand the meaning and limitations of genetic discoveries when patients raise questions about media reports. It provides a resource for clinicians who would like more information about the role and content of genetic counseling, outlining a typical counseling session while demonstrating how risks are estimated and discussed. It summarizes genetic aspects of major psychiatric conditions -- from childhood-onset disorders through psychotic, mood, and anxiety disorders to dementia -- as well as neuropsychiatric manifestations of other genetic disorders. It alerts clinicians to risk/benefit considerations related to medication use during pregnancy. It covers the ethical, legal, and social implications of genetic research and counseling, illustrating the dilemmas that arise with new advances. Whether used as a clinical guide, reference, or ancillary text, this book sets the standard for the application of psychiatric genetic knowledge in everyday practice. Psychiatrists, mental health clinicians, and genetic counselors will find it an essential resource for all patient encounters in which genetic issues arise.

Genomics Circuits and Pathways in Clinical Neuropsychiatry

Genomics  Circuits  and Pathways in Clinical Neuropsychiatry
Author: Thomas Lehner,Bruce L. Miller,Matthew W. State
Publsiher: Academic Press
Total Pages: 796
Release: 2016-06-07
ISBN 10: 0128005300
ISBN 13: 9780128005309
Language: EN, FR, DE, ES & NL

Genomics Circuits and Pathways in Clinical Neuropsychiatry Book Review:

This foundational work comprehensively examines the current state of the genetics, genomics and brain circuitry of psychiatric and neurological disorders. It consolidates discoveries of specific genes and genomic regions associated with these conditions, the genetic and anatomic architecture of these syndromes, and addresses how recent advances in genomics are leading to a reappraisal of the biology underlying clinical neuroscience. In doing so, it critically examines the promise and limitations of these discoveries toward treatment, and to the interdisciplinary nature of understanding brain and behavior. Coverage includes new discoveries regarding autism, epilepsy, intellectual disability, dementias, movement disorders, language impairment, disorders of attention, schizophrenia, and bipolar disorder. Genomics, Circuits, and Pathways in Clinical Neuropsychiatry focuses on key concepts, challenges, findings, and methods in genetics, genomics, molecular pathways, brain circuitry, and related neurobiology of neurologic and psychiatric disorders. Provides interdisciplinary appeal in psychiatry, neurology, neuroscience, and genetics Identifies key concepts, methods, and findings Includes coverage of multiple disorders from autism to schizophrenia Reviews specific genes associated with disorders Discusses the genetic architecture of these syndromes Explains how recent findings are influencing the understanding of biology Clarifies the promise of these findings for future treatment

Advances in Psychiatric Genomics

Advances in Psychiatric Genomics
Author: Anonim
Publsiher: Unknown
Total Pages: 98
Release: 2012
ISBN 10: 1928374650XXX
ISBN 13: OCLC:816389033
Language: EN, FR, DE, ES & NL

Advances in Psychiatric Genomics Book Review:

Principles of Psychiatric Genetics

Principles of Psychiatric Genetics
Author: John I. Nurnberger, Jr,Wade Berrettini
Publsiher: Cambridge University Press
Total Pages: 135
Release: 2012-09-13
ISBN 10: 1139560379
ISBN 13: 9781139560375
Language: EN, FR, DE, ES & NL

Principles of Psychiatric Genetics Book Review:

Disorders of behavior represent some of the most common and disabling diseases affecting humankind; however, despite their worldwide distribution, genetic influences on these illnesses are often overlooked by families and mental health professionals. Psychiatric genetics is a rapidly advancing field, elucidating the varied roles of specific genes and their interactions in brain development and dysregulation. Principles of Psychiatric Genetics includes 22 disorder-based chapters covering, amongst other conditions, schizophrenia, mood disorders, anxiety disorders, Alzheimer's disease, learning and developmental disorders, eating disorders and personality disorders. Supporting chapters focus on issues of genetic epidemiology, molecular and statistical methods, pharmacogenetics, epigenetics, gene expression studies, online genetic databases and ethical issues. Written by an international team of contributors, and fully updated with the latest results from genome-wide association studies, this comprehensive text is an indispensable reference for psychiatrists, neurologists, psychologists and anyone involved in psychiatric genetic studies.

Personalized Psychiatry

Personalized Psychiatry
Author: Bernhard Baune
Publsiher: Academic Press
Total Pages: 604
Release: 2019-10-16
ISBN 10: 0128131772
ISBN 13: 9780128131770
Language: EN, FR, DE, ES & NL

Personalized Psychiatry Book Review:

Personalized Psychiatry presents the first book to explore this novel field of biological psychiatry that covers both basic science research and its translational applications. The book conceptualizes personalized psychiatry and provides state-of-the-art knowledge on biological and neuroscience methodologies, all while integrating clinical phenomenology relevant to personalized psychiatry and discussing important principles and potential models. It is essential reading for advanced students and neuroscience and psychiatry researchers who are investigating the prevention and treatment of mental disorders. Combines neurobiology with basic science methodologies in genomics, epigenomics and transcriptomics Demonstrates how the statistical modeling of interacting biological and clinical information could transform the future of psychiatry Addresses fundamental questions and requirements for personalized psychiatry from a basic research and translational perspective

Research Advances in Genetics and Genomics

Research Advances in Genetics and Genomics
Author: Nancy C. Andreasen
Publsiher: American Psychiatric Pub
Total Pages: 160
Release: 2007-05-03
ISBN 10: 9781585627103
ISBN 13: 1585627100
Language: EN, FR, DE, ES & NL

Research Advances in Genetics and Genomics Book Review:

Research Advances in Genetics and Genomics: Implications for Psychiatry introduces mental health professionals to exciting breakthroughs in endophenotypes, animal models, microarrays, and genetic mapping, as well as general strategies for identifying the genetic mechanisms of mental illnesses. Uniquely valuable both as summary and signpost, this concise volume provides a fascinating overview of recent cutting-edge developments in the application of molecular genetics, genomics, and proteomics to the study of psychiatric populations. By reading Research Advances in Genetics and Genomics, you will gain a better understanding of Psychiatric Genetics -- Reviews and assesses the major research paradigms that have emerged in the field of psychiatric genetics over the several past decades, exploring the major conceptual and philosophical issues they pose and the value of their integration. Molecular Structure of Nucleic Acids -- An overview of the double-helix discovery and provides a context for current endeavors, the original one-page April 1953 Nature paper by Watson and Crick, which sparked a revolution in the life sciences. Psychiatry in the Genomics Era -- Posits that one of the most important consequences of genomics will be the development of individualized treatments that allow a clinician to tailor therapy on the basis of the unique genotype of each patient rather than on the mean responses of groups of unrelated patients. The Genomics Revolution -- Details the implications of the genome for future medical practice, including the potential for developing methods and tools to better understand, treat, and prevent major mental disorders. The Endophenotype Concept in Psychiatry -- Explains the etymology and strategy behind the use of endophenotypes in neuropsychiatric research and, more generally, in research on other diseases with complex genetics, such as schizophrenia. The Genes and Brains of Mice and Men -- Shows why a detailed assessment of brain function in mice is so important for advancing psychiatric research in humans. Humans and mice share numerous features-in fact, for an estimated 99% of human genes a mouse version may be identified-of brain organization and behavioral responses to many pharmacological agents. Microarray Technology -- Asserts that microarrays present a methodology for identifying genes or pathways for new and unique potential drug targets, determining premorbid diagnosis, predicting drug responsiveness for individual patients, and, eventually, initiating gene therapy and prevention strategies. Meticulously referenced, this volume is exceptionally useful as a starting point for understanding the impact of genetics and genomics on psychiatry, serving to introduce psychiatrists, psychologists, neurologists, and geneticists to this exciting field.

Psychiatric Genetics

Psychiatric Genetics
Author: Thomas Schulze,Francis McMahon
Publsiher: Oxford University Press
Total Pages: 135
Release: 2018-04-06
ISBN 10: 0190221992
ISBN 13: 9780190221997
Language: EN, FR, DE, ES & NL

Psychiatric Genetics Book Review:

Psychiatrists and other mental health professionals are increasingly confronted with questions about the genetics of psychiatric illness, and the clinical applications of new genetic findings. Psychiatric Genetics: A Primer for Clinical and Basic Scientists addresses these questions through a straightforward introduction to the essentials of psychiatric genetics, complementing more comprehensive textbooks that may seem overwhelming for those new to the field. Written and edited by leaders in the field and the International Society of Psychiatric Genetics (ISPG), the book covers basic epidemiology, recruitment for human studies, phenotyping strategies, formal genetic and molecular genetic studies, statistical genetics, bioinformatics and genomics, pharmacogenetics, the most relevant animal models, and biobanking. Each chapter begins with a list of "take home" points that summarizes content, followed by a brief overview of current knowledge and suggestions for further reading. This Primer is ideal for medical students, psychiatric residents, psychiatrists, and basic neuroscience researchers who are interested in learning about the key concepts and recent advances in the exciting field of psychiatric genetics.

Lasso Meta regression and Its Application to Psychiatric Genomics

Lasso Meta regression and Its Application to Psychiatric Genomics
Author: Charles A. Laurin
Publsiher: Unknown
Total Pages: 85
Release: 2014
ISBN 10: 1928374650XXX
ISBN 13: OCLC:879645551
Language: EN, FR, DE, ES & NL

Lasso Meta regression and Its Application to Psychiatric Genomics Book Review:

Epigenetics in Psychiatry

Epigenetics in Psychiatry
Author: Jacob Peedicayil,Dennis R. Grayson,Dimitri Avramopoulos
Publsiher: Academic Press
Total Pages: 846
Release: 2021-08-16
ISBN 10: 0128235780
ISBN 13: 9780128235782
Language: EN, FR, DE, ES & NL

Epigenetics in Psychiatry Book Review:

Epigenetics in Psychiatry, Second Edition covers all major areas of psychiatry in which extensive epigenetic research has been performed, fully encompassing a diverse and maturing field, including drug addiction, bipolar disorder, epidemiology, cognitive disorders, and the uses of putative epigenetic-based psychotropic drugs. Uniquely, each chapter correlates epigenetics with relevant advances across genomics, transcriptomics, and proteomics. The book acts as a catalyst for further research in this growing area of psychiatry. This new edition has been fully revised to address recent advances in epigenetic understanding of psychiatric disorders, evoking data consortia (e.g., CommonMind, ATAC-seq), single cell analysis, and epigenome-wide association studies to empower new research. The book also examines epigenetic effects of the microbiome on psychiatric disorders, and the use of neuroimaging in studying the role of epigenetic mechanisms of gene expression. Ongoing advances in epigenetic therapy are explored in-depth. Fully revised to discuss new areas of research across neuronal stem cells, cognitive disorders, and transgenerational epigenetics in psychiatric disease Relates broad advances in psychiatric epigenetics to a modern understanding of the genome, transcriptome, and proteins Catalyzes knowledge discovery in both basic epigenetic biology and epigenetic targets for drug discovery Provides guidance in research methods and protocols, as well how to employ data from consortia, single cell analysis, and epigenome-wide association studies (EWAS) Features chapter contributions from international leaders in the field

Psychiatric Genetics

Psychiatric Genetics
Author: Michael Arribas-Ayllon,Andrew Bartlett,Jamie Lewis
Publsiher: Routledge
Total Pages: 234
Release: 2019-02-21
ISBN 10: 1317329635
ISBN 13: 9781317329633
Language: EN, FR, DE, ES & NL

Psychiatric Genetics Book Review:

Psychiatric genetics has become ‘Big Biology’. This may come as a surprising development to those familiar with its controversial history. From eugenic origins and contentious twin studies to a global network of laboratories employing high-throughput genetic and genomic technologies, biological research on psychiatric disorders has become an international, multidisciplinary assemblage of massive data resources. How did psychiatric genetics achieve this scale? How is it socially and epistemically organized? And how do scientists experience this politics of scale? Psychiatric Genetics: From Hereditary Madness to Big Biology develops a sociological approach of exploring the origins of psychiatric genetics by tracing several distinct styles of scientific reasoning that coalesced at the beginning of the twentieth century. These styles of reasoning reveal, among other things, a range of practices that maintain an extraordinary stability in the face of radical criticism, internal tensions and scientific disappointments. The book draws on a variety of methods and materials to explore these claims. Combining genealogical analysis of historical literature, rhetorical analysis of scientific review articles, interviews with scientists, ethnographic observations of laboratory practices and international conferences, this book offers a comprehensive and detailed exploration of both local and global changes in the field of psychiatric genetics.

Psychiatric Genetics

Psychiatric Genetics
Author: Kenneth S. Kendler,Lindon J. Eaves
Publsiher: American Psychiatric Pub
Total Pages: 256
Release: 2007-05-03
ISBN 10: 9781585627066
ISBN 13: 1585627062
Language: EN, FR, DE, ES & NL

Psychiatric Genetics Book Review:

Psychiatric Genetics is a concise reference that presents the complexities of this dynamic field in a clearly written, easily accessible format, with numerous tables and illustrations. Ten expert contributors offer a fascinating view of psychiatric genetics in a text that is thorough and scholarly yet also succinct and accessible. The introduction summarizes the field's four distinct paradigms -- and their interrelationships -- that help us understand the role of genetic factors in the etiology of psychiatric disorders: basic genetic epidemiology, which demonstrates heritability; advanced genetic epidemiology, which explores the nature and mode of action of these genetic risk factors; gene finding, which enables us to infer the probability that a locus in the genomic region under investigation contributes to psychiatric disorder liability; and molecular genetics, which traces the biological mechanisms by which the DNA variant identified using gene finding methods contributes to the disorder itself. Psychiatric Genetics illustrates the importance of Appreciating the complex field of psychiatric genetics -- Presents the major conceptual and statistical issues in psychiatric genetics, including many of the basic principles of both genetic epidemiology and gene finding, as well as a brief review of DNA itself. Detailing the results for one disorder where substantial progress had been made in gene finding and molecular genetics -- Covers schizophrenia, because of the substantial progress made during the past few years. Presenting results for a more typical and common set of psychiatric disorders where most of our information comes from basic and advanced genetic epidemiology and where we are just beginning to make advances using gene finding -- Discusses anxiety disorders, which illustrate these sets of issues. Covering disorders where major advances have been made using basic and advanced genetic epidemiology -- Details substance use disorders, where the paradigm has shifted from sociological to genetic factors and where, in contrast to the genetics of more traditional psychiatric disorders, researchers must consider the inherent conditionality of drug abuse. Investigating the role of genetics in personality disorders -- Focuses on the development of conduct and antisocial behavior and how to incorporate developmental processes into analyses of the role of genetics. Psychiatric Genetics draws students, educators, and practitioners alike into the exciting world of psychiatric genetics with a lively discussion of its broad trends and of the strengths and limitations of its methods to provide true insight into the etiology of psychiatric and substance use disorders.

How to Talk with Families About Genetics and Psychiatric Illness

How to Talk with Families About Genetics and Psychiatric Illness
Author: Holly Landrum Peay,Jehannine Claire Austin
Publsiher: W. W. Norton & Company
Total Pages: 280
Release: 2011-01-17
ISBN 10: 0393706796
ISBN 13: 9780393706796
Language: EN, FR, DE, ES & NL

How to Talk with Families About Genetics and Psychiatric Illness Book Review:

Addressing clients’ questions and concerns about the role of genetics in mental illness. As we learn more about how our biology and genes can play into the development of a mental health disorder, patients and their families are increasingly seeking answers to tough questions about common risk factors, the likelihood of recurrence, the need for genetic testing, and implications for future generations. A practical, go-to resource for all mental health clinicians, this guide explains just how to address these questions and concerns in a way that’s comprehensible and compassionate. Filled with case studies, sample dialogues, and question-and-answer examples, it is an essential roadmap for practitioners, helping them to demystify a complex issue for their clients and equip them with the accurate, reassuring information they need.

Textbook of Psychiatric Epidemiology

Textbook of Psychiatric Epidemiology
Author: Ming T. Tsuang,Mauricio Tohen,Peter Jones
Publsiher: John Wiley & Sons
Total Pages: 646
Release: 2011-04-25
ISBN 10: 047069467X
ISBN 13: 9780470694671
Language: EN, FR, DE, ES & NL

Textbook of Psychiatric Epidemiology Book Review:

Rev. ed. of: Textbook in psychiatric epidemiology / edited by Ming T. Tsuang, Mauricio Tohen. 2nd ed. c2002.

Psychiatric Genetics

Psychiatric Genetics
Author: Marion Leboyer,Frank Bellivier
Publsiher: Springer Science & Business Media
Total Pages: 280
Release: 2003
ISBN 10: 1592593488
ISBN 13: 9781592593484
Language: EN, FR, DE, ES & NL

Psychiatric Genetics Book Review:

Psychiatric Genetics provides the reader with a complete view of the methodological problems encountered in psychiatry genetics and proposes solutions to commonly occurring questions. The best European and American specialists have given a thorough review on the advantages and disadvantages of genetic epidemiological methods, the way to choose a genetic marker or a clinical interview and how to ascertain patients, unaffected relatives and controls and what should be the criteria to include a case or a control. New phenotypic methods are described focusing on candidate symptom and endophenotype approaches. Examples coming from cognitive neurosciences, biochemistry, electrophysiology and brain imaging techniques are reviewed. This book will serve as an essential handbook for psychiatrists, psychologists, and geneticists.

Handbook of Psychiatric Genetics

Handbook of Psychiatric Genetics
Author: Kenneth Blum,Ernest P. Noble
Publsiher: CRC Press
Total Pages: 512
Release: 1996-10-29
ISBN 10: 9780849344862
ISBN 13: 0849344867
Language: EN, FR, DE, ES & NL

Handbook of Psychiatric Genetics Book Review:

Psychiatric genetics is an exciting new discipline that explores how our minds and behavior are influenced by our genes. Increased interest in this area of medical genetics has been sparked by advances in molecular genetic techniques, the genome project, the neurosciences, the role of genes in somatic diseases, and the linking of specific genes with complex mental disorders. This Handbook is the definitive resource on this complex, and sometimes controversial, new field.