Prognostic and Therapeutic Applications of Rkip in Cancer

Prognostic and Therapeutic Applications of Rkip in Cancer
Author: Benjamin Bonavida,Stavroula Baritaki
Publsiher: Academic Press
Total Pages: 504
Release: 2020-03-02
ISBN 10: 0128196122
ISBN 13: 9780128196120
Language: EN, FR, DE, ES & NL

Prognostic and Therapeutic Applications of Rkip in Cancer Book Review:

Prognostic and Therapeutic Applications of RKIP in Cancer provides updated reviews on the chemistry, signaling, pre-clinical and clinical activities, and role of RKIP expression levels for diagnostics, prognosis and potential interventions. The development of novel compounds and conjugates that selectively induce RKIP expression in cancer open a novel era of new therapeutics and their potential in the treatment of highly resistant cancers and metastases. Edited and written by internationally renowned experts in the field of novel therapeutics for cancer, this book is a valuable source for cancer researchers, medical scientists, clinicians, clinical pharmacologists, and graduate students. Provides an update from experts in the field on diagnostics, prognostics and therapeutics Brings a clear overview of recent findings and references, as well as summaries, significant molecular pathways, and conclusions in each chapter Provides a general introductory chapter on contributions in the field and a chapter summary, with synthesized findings and a projection of future goals

Prognostic and Therapeutic Applications of RKIP in Cancer

Prognostic and Therapeutic Applications of RKIP in Cancer
Author: Benjamin Bonavida,Stavroula Baritaki
Publsiher: Academic Press
Total Pages: 504
Release: 2020-02-03
ISBN 10: 0128224517
ISBN 13: 9780128224519
Language: EN, FR, DE, ES & NL

Prognostic and Therapeutic Applications of RKIP in Cancer Book Review:

Prognostic and Therapeutic Applications of RKIP in Cancer provides updated reviews on the chemistry, signaling, pre-clinical and clinical activities, and role of RKIP expression levels for diagnostics, prognosis and potential interventions. The development of novel compounds and conjugates that selectively induce RKIP expression in cancer open a novel era of new therapeutics and their potential in the treatment of highly resistant cancers and metastases. Edited and written by internationally renowned experts in the field of novel therapeutics for cancer, this book is a valuable source for cancer researchers, medical scientists, clinicians, clinical pharmacologists, and graduate students. Provides an update from experts in the field on diagnostics, prognostics and therapeutics Brings a clear overview of recent findings and references, as well as summaries, significant molecular pathways, and conclusions in each chapter Provides a general introductory chapter on contributions in the field and a chapter summary, with synthesized findings and a projection of future goals

Nitric Oxide NO and Cancer

Nitric Oxide  NO  and Cancer
Author: Benjamin Bonavida
Publsiher: Springer Science & Business Media
Total Pages: 250
Release: 2010-06-16
ISBN 10: 9781441914323
ISBN 13: 1441914323
Language: EN, FR, DE, ES & NL

Nitric Oxide NO and Cancer Book Review:

Nitric Oxide (NO) is a pleitropic, ubiquitous modulator of cellular functions. Aryl nitrite and glyceryl trinitrate, representative intravasadilators, were introduced as therapeutic agents more than a century ago for relief from acute attacks of angina. The vasodilator action is mediated by the release of NO following treatment. NO has important therapeutic applications in several diseases such as inflammatory diseases, erectile dysfunction, inflammation, pain and neural protective activity. However, the role of NO in cancer and its application in therapy has received little attention. This monograph will be the first to focus on studies that investigate the role of NO in tumor cell pathogenesis, growth, angiogenesis, response to cytotoxic therapies and NO translational applications in cancer therapy, alone or in conjunction with other therapies.

Handbook of Immunohistochemistry and in Situ Hybridization of Human Carcinomas

Handbook of Immunohistochemistry and in Situ Hybridization of Human Carcinomas
Author: M. A. Hayat
Publsiher: Elsevier
Total Pages: 492
Release: 2005-01-31
ISBN 10: 0080495206
ISBN 13: 9780080495200
Language: EN, FR, DE, ES & NL

Handbook of Immunohistochemistry and in Situ Hybridization of Human Carcinomas Book Review:

Immunohistochemistry is the use of specific antibodies to stain particular molecular species in situ. This technique has allowed the identification of many more cell types than could be visualized by classical histology, particularly in the immune system and among the scattered hormone-secreting cells of the endocrine system, and has the potential to improve diagnosis, prognosis and therapeutic options of cancer. Handbook of Immunohistochemistry and in Situ Hybridization of Human Carcinomas discusses all aspects of immunohistochemistry and in situ hybridization technologies and the important role they play in reaching a cancer diagnosis. It provides step-by-step instructions on the methods of additional molecular technologies such as DNA microarrays, and microdissection, along with the benefits and limitations of each method. The topics of region-specific gene expression, its role in cancer development and the techniques that assist in the understanding of the molecular basis of disease are relevant and necessary in science today. This book is the second volume of three planned, individually-sold volumes on this topic. Like Volume 1, this book fully explains the principles and applications of modern techniques used in the field of molecular genetics. It will be of particular interest to pathologists and molecular pathologists conducting both academic and/or clinical research. The only book available that translates molecular genetics into cancer diagnosis The results of each Immunohistochemical and in situ hybridization method are presented in the form of color illustrations Methods discussed were either developed or refined by expert contributors in their own laboratories

Oncogene and Cancer

Oncogene and Cancer
Author: Yahwardiah Siregar
Publsiher: Inst za onkologiju i radiol
Total Pages: 498
Release: 2013-01-24
ISBN 10: 9535108581
ISBN 13: 9789535108580
Language: EN, FR, DE, ES & NL

Oncogene and Cancer Book Review:

This book describes a course of cancer growth starting from normal cells to cancerous form and the genomic instability, the cancer treatment as well as its prevention in form of the invention of a vaccine. Some diseases are also discussed in detail, such as breast cancer, leucaemia, cervical cancer, and glioma. Understanding cancer through its molecular mechanism is needed to reduce the cancer incidence. How to treat cancer more effectively and the problems like drug resistance and metastasis are very clearly illustrated in this publication as well as some research result that could be used to treat the cancer patients in the very near future. The book was divided into six main sections: 1. HER2 Carcinogenesis: Etiology, Treatment and Prevention; 2. DNA Repair Mechanism and Cancer; 3. New Approach to Cancer Mechanism; 4. New Role of Oncogenes and Tumor Suppressor Genes; 5. Non Coding RNA and Micro RNA in Tumorigenesis; 6. Oncogenes for Transcription Factors

The Role of ncRNAs in Solid Tumors Prognosis From Laboratory To Clinical Utility

The Role of ncRNAs in Solid Tumors Prognosis  From Laboratory To Clinical Utility
Author: Jian-Guo Zhou,Zhaohui Huang,Ondrej Slaby,Alfons Navarro
Publsiher: Frontiers Media SA
Total Pages: 135
Release: 2021-03-23
ISBN 10: 2889666093
ISBN 13: 9782889666096
Language: EN, FR, DE, ES & NL

The Role of ncRNAs in Solid Tumors Prognosis From Laboratory To Clinical Utility Book Review:

Immunohistochemical Expression

Immunohistochemical Expression
Author: Rosario Caltabiano,Carla Loreto
Publsiher: MDPI
Total Pages: 168
Release: 2021-09-02
ISBN 10: 3036504001
ISBN 13: 9783036504001
Language: EN, FR, DE, ES & NL

Immunohistochemical Expression Book Review:

Immunohistochemistry (IHC) is an ancillary method, widely used in pathologists’ practice, that allows identifying diagnostic and prognostic/predictive of therapeutic response protein markers on tissue samples by the use of specific monoclonal antibodies and chromogenic substances that guarantee the visualization of an antibody–antigene binding complex under a light microscope [1]. Coon et al., in 1941 [2], first introduced the use of fluorochrome-conjugated antibodies in clinical practice. Since then, IHC has gone from being a useful tool for identifying the differentiation line of otherwise undifferentiated cells to a technique capable of providing not only diagnostic but also prognostic and predictive indications of responses to specific therapeutic options [1,3]. The abovementioned peculiarities have made IHC one of the most used ancillary methods in the histopathological approach to human neoplastic and non-neoplastic diseases [3-5]. This Special Issue contains 11 accepted papers that provide readers with a comprehensive update on current and future applications of IHC in medical practice.

Methods of Cancer Diagnosis Therapy and Prognosis

Methods of Cancer Diagnosis  Therapy and Prognosis
Author: M. A. Hayat
Publsiher: Springer Science & Business Media
Total Pages: 503
Release: 2009-03-28
ISBN 10: 1402095457
ISBN 13: 9781402095450
Language: EN, FR, DE, ES & NL

Methods of Cancer Diagnosis Therapy and Prognosis Book Review:

This fourth volume in a series devoted to cancer treatment discusses various methodologies for the diagnosis, therapy and prognosis of colorectal cancer. It covers the latest information including standard and emerging therapies and technological advances.

Advances in Prostate Cancer

Advances in Prostate Cancer
Author: Gerhard Hamilton
Publsiher: BoD – Books on Demand
Total Pages: 704
Release: 2013-01-16
ISBN 10: 9535109324
ISBN 13: 9789535109327
Language: EN, FR, DE, ES & NL

Advances in Prostate Cancer Book Review:

Prostate cancer is one of the most common types of cancer in men and its treatment was constricted to surgery for confined state and androgen ablation for advanced disease until new options have become available. The present book covers a broad range of novel aspects of prostate cancer diagnosis, treatment and patient care, as well as new research on relevant cell biology. In detail, this special volume focusses on supportive modalities for prostate cancer patients, appropriate selection of novel therapeutic regimens, including inhibitors of steroidal synthesis, cytotoxic agents, as well as intermittent androgen suppression and the roles of prostate cancer stem cells and inflammatory processes.

Growth Factor Receptors Advances in Research and Application 2013 Edition

Growth Factor Receptors   Advances in Research and Application  2013 Edition
Author: Anonim
Publsiher: ScholarlyEditions
Total Pages: 222
Release: 2013-06-21
ISBN 10: 1481688405
ISBN 13: 9781481688406
Language: EN, FR, DE, ES & NL

Growth Factor Receptors Advances in Research and Application 2013 Edition Book Review:

Growth Factor Receptors—Advances in Research and Application: 2013 Edition is a ScholarlyEditions™ book that delivers timely, authoritative, and comprehensive information about Bone Morphogenetic Protein Receptors. The editors have built Growth Factor Receptors—Advances in Research and Application: 2013 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Bone Morphogenetic Protein Receptors in this book to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Growth Factor Receptors—Advances in Research and Application: 2013 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Cancer Epigenetics

Cancer Epigenetics
Author: Mukesh Verma
Publsiher: Humana Press
Total Pages: 804
Release: 2014-11-25
ISBN 10: 9781493918034
ISBN 13: 1493918036
Language: EN, FR, DE, ES & NL

Cancer Epigenetics Book Review:

This volume shares technologies that detect common epigenetic changes which are very important in the early detection, progression, and prognosis of cancer as well as the design of new therapeutic tools against cancer cells. Beginning with a bit of background on epigenetic mechanisms, Cancer Epigenetics: Risk Assessment, Diagnosis, Treatment, and Prognosis continues with cancer specific type epigenetic change, methods and technologies used for detecting epigenetic changes, factors that influence epigenetic changes in cancer, as well as a final section on future directions in the field. Written for the highly successful Methods in Molecular Biology series, chapters in this volume include the kind of detailed implementation advice that guarantees easily reproducible results. Comprehensive and practical, Cancer Epigenetics: Risk Assessment, Diagnosis, Treatment, and Prognosis provides the most up-to-date knowledge of epigenetics and its implication in cancer prevention by risk assessment and screening and cancer control by treatment.

Hemic and Lymphatic Diseases New Insights for the Healthcare Professional 2013 Edition

Hemic and Lymphatic Diseases  New Insights for the Healthcare Professional  2013 Edition
Author: Anonim
Publsiher: ScholarlyEditions
Total Pages: 177
Release: 2013-07-22
ISBN 10: 1481659243
ISBN 13: 9781481659246
Language: EN, FR, DE, ES & NL

Hemic and Lymphatic Diseases New Insights for the Healthcare Professional 2013 Edition Book Review:

Hemic and Lymphatic Diseases: New Insights for the Healthcare Professional: 2013 Edition is a ScholarlyEditions™ book that delivers timely, authoritative, and comprehensive information about Diagnosis and Screening. The editors have built Hemic and Lymphatic Diseases: New Insights for the Healthcare Professional: 2013 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Diagnosis and Screening in this book to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Hemic and Lymphatic Diseases: New Insights for the Healthcare Professional: 2013 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Leukemia

Leukemia
Author: Margarita Guenova,Gueorgui Balatzenko
Publsiher: BoD – Books on Demand
Total Pages: 254
Release: 2013-05-15
ISBN 10: 9535111272
ISBN 13: 9789535111276
Language: EN, FR, DE, ES & NL

Leukemia Book Review:

Leukemias are a group of heterogeneous neoplastic disorders, that differ significantly in terms of morhological, immunophenotypic, cytogenetic and molecular features of malignant cells. These specific features reflect the differences in the spectrum of underlying biological alterations involved in malignant transformation, and/or variations in the level of hematopoietic stem cells hierarchy where the transforming events occur. The continuous and rather extensive influx of new information regarding the pathogenesis and treatment of leukemias requires a frequent updating of this topic. The primary objective of this book is to provide the specialists involved in the diagnosis and management of acute and chronic leukemias with a comprehensive and concise information on some important theoretical and practical issues of the biology and clinical presentation, the diagnosis, treatment and follow up of patients with leukemias.

Advancements of Mass Spectrometry in Biomedical Research

Advancements of Mass Spectrometry in Biomedical Research
Author: Alisa G. Woods,Costel C. Darie
Publsiher: Springer
Total Pages: 600
Release: 2014-06-20
ISBN 10: 3319060686
ISBN 13: 9783319060682
Language: EN, FR, DE, ES & NL

Advancements of Mass Spectrometry in Biomedical Research Book Review:

This volume explores the use of mass spectrometry for biomedical applications. Chapters focus on specific therapeutic areas such as oncology, infectious disease and psychiatry. Additional chapters focus on methodology as well as new technologies and instrumentation. This volume provides readers with a comprehensive and informative manual that will allow them to appreciate mass spectrometry and proteomic research but also to initiate and improve their own work. Thus the book acts as a technical guide but also a conceptual guide to the newest information in this exciting field. Mass spectrometry is the central tool used in proteomic research today and is rapidly becoming indispensable to the biomedical scientist. With the completion of the human genome project and the genomic revolution, the proteomic revolution has followed closely behind. Understanding the human proteome has become critical to basic and clinical biomedical research and holds the promise of providing comprehensive understanding of human physiological processes. In addition, proteomics and mass spectrometry are bringing unprecedented biomarker discovery and are helping to personalize medicine.

Nitric Oxide

Nitric Oxide
Author: Louis J. Ignarro
Publsiher: Academic Press
Total Pages: 845
Release: 2009-11-05
ISBN 10: 9780080920443
ISBN 13: 0080920446
Language: EN, FR, DE, ES & NL

Nitric Oxide Book Review:

Nitric oxide (NO) is a gas naturally found in the body that conveys information between cells. In the last decade researchers have found that NO is a signaling molecule of key importance for the cardiovascular system, regulating blood pressure and blood flow to different organs. In addition, discoveries surrounding nitric oxide’s role as a principal neurotransmitter moderating erectile function, a pathophysiological negotiator and messenger in inflammation, and a weapon against infections have increased research attention across the fields of biochemistry, chemistry, molecular biology, gene therapy, cell biology, immunology, pharmacology, neuroscience, and physiology. Edited by Nobel Laureate Louis J. Ignarro Up-to-date therapeutic implications of nitric oxide research Authored by world experts on nitric oxide Detailed research of the biochemistry and synthesis of nitric oxide

The Unfolded Protein Response in Cancer

The Unfolded Protein Response in Cancer
Author: Robert Clarke
Publsiher: Springer
Total Pages: 220
Release: 2019-03-01
ISBN 10: 303005067X
ISBN 13: 9783030050672
Language: EN, FR, DE, ES & NL

The Unfolded Protein Response in Cancer Book Review:

This volume presents state-of-the-art information on each of the arms of the unfolded protein response (UPR), how their activation/repression are regulated, integrated, and coordinated, how UPR components affect cancer cell biology and responsiveness to therapeutic interventions, and how UPR components/activities offer potentially novel targets for drug discovery, repurposing, and development. The volume will provide the most recent information on the signaling and regulation of the UPR, explore examples of how the UPR and/or specific components contribute to cancer biology, and identify and explore specific examples of potently new actionable targets for drug discovery and development from within the UPR and its regulation. Unique to the volume will be a specific focus on the UPR and its role in cancer biology, as well as a discussion of the role of the UPR in drug responses and resistance in cancer.

The Epithelial to Mesenchymal Transition EMT in Cancer

The Epithelial to Mesenchymal Transition  EMT  in Cancer
Author: Joëlle Roche
Publsiher: MDPI
Total Pages: 260
Release: 2018-04-09
ISBN 10: 3038427934
ISBN 13: 9783038427933
Language: EN, FR, DE, ES & NL

The Epithelial to Mesenchymal Transition EMT in Cancer Book Review:

This book is a printed edition of the Special Issue "The Epithelial-to-Mesenchymal Transition (EMT) in Cancer" that was published in Cancers

Resistance to Anti Cancer Therapeutics Targeting Receptor Tyrosine Kinases and Downstream Pathways

Resistance to Anti Cancer Therapeutics Targeting Receptor Tyrosine Kinases and Downstream Pathways
Author: Yosef Yarden,Moshe Elkabets
Publsiher: Springer
Total Pages: 242
Release: 2019-02-02
ISBN 10: 9783030098179
ISBN 13: 3030098176
Language: EN, FR, DE, ES & NL

Resistance to Anti Cancer Therapeutics Targeting Receptor Tyrosine Kinases and Downstream Pathways Book Review:

This volume comprehensively covers the multiplicity and diversity of mechanisms underlying patient resistance to currently approved anti-cancer drugs, including tyrosine kinase inhibitors and monoclonal antibodies, blockers of growth factor receptors and their downstream pathways, which play essential functions in cancer progression. Each chapter will cover a specific group of targets and the cognate drugs, along with molecular modes of innate and evolving resistance.

Pocket Oncology

Pocket Oncology
Author: Alexander Drilon,Michael Postow,Neil Vasan,Maria I. Carlo
Publsiher: Lippincott Williams & Wilkins
Total Pages: 374
Release: 2018-02-07
ISBN 10: 1496391055
ISBN 13: 9781496391056
Language: EN, FR, DE, ES & NL

Pocket Oncology Book Review:

Written and edited by leading cancer experts at Memorial Sloan Kettering Cancer Center, Pocket Oncology, Second Edition, is a practical, high-yield reference for trainees and practitioners of medical oncology and hematology. This easy-to-use, loose-leaf resource contains up-to-date information essential to caring for patients with cancer, from cancer biology, prevention, screening, treatment and supportive care to new advances in immuno-oncology and precision medicine.

Cancer Epidemiology and Prevention

Cancer Epidemiology and Prevention
Author: David Schottenfeld,Joseph F. Fraumeni Jr.
Publsiher: Oxford University Press
Total Pages: 1416
Release: 2006-08-24
ISBN 10: 9780199747979
ISBN 13: 0199747970
Language: EN, FR, DE, ES & NL

Cancer Epidemiology and Prevention Book Review:

This much anticipated Third Edition provides a comprehensive presentation of the global burden and patterns of cancer occurrence, along with new developments in our understanding of cancer causation and prevention. Special attention is given to epidemiologic approaches that incorporate molecular biomarkers based on genomic and other emerging technologies, providing new insights into the role of genetic predisposition and gene-environment interactions in cancer induction. In addition, new chapters are included on social class disparities in cancer incidence and mortality, the role of obesity and physical inactivity in cancer etiology, the potential effects of electromagnetic fields and rediofrequency radiation, and the principles of cancer chemoprevention. The textbook is organized into five sections: Basic Concepts; The Magnitude of Cancer; The Causes of Cancer; Cancer by Tissue of Origin; Cancer Prevention and Control. In this new edition, Drs. David Schottenfeld and Joseph F. Fraumeni, Jr. have enlisted three distinguished Associate Editors: Drs. Jonathan Samet of Johns Hopkins University, Graham Colditz of Harvard University and Alice Whittemore of Stanford University.