Lab-on-a-Chip Fabrication and Application

Lab-on-a-Chip Fabrication and Application
Author: Margarita Stoytcheva,Roumen Zlatev
Publsiher: BoD – Books on Demand
Total Pages: 208
Release: 2016-06-29
ISBN 10: 9535124579
ISBN 13: 9789535124573
Language: EN, FR, DE, ES & NL

Lab-on-a-Chip Fabrication and Application Book Review:

The necessity of on-site, fast, sensitive, and cheap complex laboratory analysis, associated with the advances in the microfabrication technologies and the microfluidics, made it possible for the creation of the innovative device lab-on-a-chip (LOC), by which we would be able to scale a single or multiple laboratory processes down to a chip format. The present book is dedicated to the LOC devices from two points of view: LOC fabrication and LOC application.

Microfluidic Cell Culture Systems

Microfluidic Cell Culture Systems
Author: Jeffrey T Borenstein,Vishal Tandon,Sarah L Tao,Joseph L. Charest
Publsiher: Elsevier
Total Pages: 396
Release: 2018-09-12
ISBN 10: 0128136723
ISBN 13: 9780128136720
Language: EN, FR, DE, ES & NL

Microfluidic Cell Culture Systems Book Review:

Techniques for microfabricating intricate microfluidic structures that mimic the microenvironment of tissues and organs, combined with the development of biomaterials with carefully engineered surface properties, have enabled new paradigms in and cell culture-based models for human diseases. The dimensions of surface features and fluidic channels made accessible by these techniques are well-suited to the size scale of biological cells. Microfluidic Cell Culture Systems applies design and experimental techniques used in in microfluidics, and cell culture technologies to organ-on-chip systems. This book is intended to serve as a professional reference, providing a practical guide to design and fabrication of microfluidic systems and biomaterials for use in cell culture systems and human organ models. The book covers topics ranging from academic first principles of microfluidic design, to clinical translation strategies for cell culture protocols. The goal is to help professionals coming from an engineering background to adapt their expertise for use in cell culture and organ models applications, and likewise to help biologists to design and employ microfluidic technologies in their cell culture systems. This 2nd edition contains new material that strengthens the focus on in vitro models useful for drug discovery and development. One new chapter reviews liver organ models from an industry perspective, while others cover new technologies for scaling these models and for multi-organ systems. Other new chapters highlight the development of organ models and systems for specific applications in disease modeling and drug safety. Previous chapters have been revised to reflect the latest advances. Provides design and operation methodology for microfluidic and microfabricated materials and devices for organ-on-chip disease and safety models. This is a rapidly expanding field that will continue to grow along with advances in cell biology and microfluidics technologies. Comprehensively covers strategies and techniques ranging from academic first principles to industrial scale-up approaches. Readers will gain insight into cell-material interactions, microfluidic flow, and design principles. Offers three fundamental types of information: 1) design principles, 2) operation techniques, and 3) background information/perspectives. The book is carefully designed to strike a balance between these three areas, so it will be of use to a broad range of readers with different technical interests and educational levels.

Principles of Tissue Engineering

Principles of Tissue Engineering
Author: Robert Lanza,Robert Langer,Joseph P. Vacanti
Publsiher: Academic Press
Total Pages: 1936
Release: 2013-10-17
ISBN 10: 0123983703
ISBN 13: 9780123983701
Language: EN, FR, DE, ES & NL

Principles of Tissue Engineering Book Review:

Now in its fourth edition, Principles of Tissue Engineering has been the definite resource in the field of tissue engineering for more than a decade. The fourth edition provides an update on this rapidly progressing field, combining the prerequisites for a general understanding of tissue growth and development, the tools and theoretical information needed to design tissues and organs, as well as a presentation by the world’s experts of what is currently known about each specific organ system. As in previous editions, this book creates a comprehensive work that strikes a balance among the diversity of subjects that are related to tissue engineering, including biology, chemistry, material science, and engineering, among others, while also emphasizing those research areas that are likely to be of clinical value in the future. This edition includes greatly expanded focus on stem cells, including induced pluripotent stem (iPS) cells, stem cell niches, and blood components from stem cells. This research has already produced applications in disease modeling, toxicity testing, drug development, and clinical therapies. This up-to-date coverage of stem cell biology and other emerging technologies –such as brain-machine interfaces for controlling bionics and neuroprostheses– is complemented by a series of new and updated chapters on recent clinical experience in applying tissue engineering, as well as a new section on the application of tissue-engineering techniques for food production. The result is a comprehensive textbook that will be useful to students and experts alike. Includes new chapters on biomaterial-protein interactions, nanocomposite and three-dimensional scaffolds, skin substitutes, spinal cord, vision enhancement, and heart valves Offers expanded coverage of adult and embryonic stem cells of the cardiovascular, hematopoietic, musculoskeletal, nervous, and other organ systems Full-color presentation throughout

Nanopharmaceuticals: Principles and Applications Vol. 1

Nanopharmaceuticals: Principles and Applications Vol. 1
Author: Vinod Kumar Yata,Shivendu Ranjan,Nandita Dasgupta,Eric Lichtfouse
Publsiher: Springer Nature
Total Pages: 381
Release: 2020-07-14
ISBN 10: 3030449254
ISBN 13: 9783030449254
Language: EN, FR, DE, ES & NL

Nanopharmaceuticals: Principles and Applications Vol. 1 Book Review:

This book discusses the biological, technical and study-design challenges of Nanopharmaceuticals. Chapters of this book are dedicated to supermagentic iron oxide nanoparticles for the diagnosis of brain, breast, gastric, ovarian, liver, colorectal, lung and pancreatic cancers. It also includes a brief introduction to magnetic resonance imaging and ends with the future prospective of iron oxide nanoparticles in cancer detection. The book also provides a critical discussion on ‘Computational sequence design for DNA nanostructures’ and gives a brief introduction about the skin delivery. A detailed discussion has been included about the different types of nanocarriers such as micells, microemulsions, nanoemulsions, polymeric and lipid based nanoparticles. Focussing on the safety concerns of nanomedicine it also covers the safety issues, clinical benefits, ecotoxicity and regulatory frame work of nanopharmaceuticals.

Designing Nanostructures at the Interface between Biomedical and Physical Systems

Designing Nanostructures at the Interface between Biomedical and Physical Systems
Author: The National Academies,The National Academies Keck Futures Initiative Nanoscience and Nanotechnology Planning Committee,The National Academies Keck Futures Initiative Nanoscience and Nanotechnology Steering Committee
Publsiher: National Academies Press
Total Pages: 120
Release: 2005-07-01
ISBN 10: 0309096685
ISBN 13: 9780309096683
Language: EN, FR, DE, ES & NL

Designing Nanostructures at the Interface between Biomedical and Physical Systems Book Review:

Last November, the National Academies Keck Futures Initiative held the Designing Nanostructures at the Interface Between Biomedical and Physical Systems conference at which researchers from science, engineering and medicine discussed recent developments in nanotechnology, directions for future research, and possible biomedical applications. The centerpiece of the conference was breakout sessions in which ten focus groups of researchers from different fields spent eight hours developing research plans to solve various problems in the field of nanotechnology. Among the challenges were: Building a nanosystem that can isolate, sequence and identify RNA or DNA Developing a system to detect disease in vivo Sequencing a single molecule of protein Creating a biological system that will create a local hydrogen fuel source, and Growing a biological in vivo power source. Representatives from public and private funding organizations, government, industry, and the science media also participated in the focus groups. This book provides a summary of the conference focus groups. For more information about the conference, visit Keck Futures Initiative. The National Academies Keck Futures Initiative was launched in 2003 to stimulate new modes of scientific inquiry and break down the conceptual and institutional barriers to interdisciplinary research. The National Academies and the W.M. Keck Foundation believe considerable scientific progress and social benefit will be achieved by providing a counterbalance to the tendency to isolate research within academic fields. The Futures Initiative is designed to enable researchers from different disciplines to focus on new questions upon which they can base entirely new research, and to encourage better communication between scientists as well as between the scientific community and the public. Funded by a $40 million grant from the W.M. Keck Foundation, the National Academies Keck Futures Initiative is a 15-year effort to catalyze interdisciplinary inquiry and to enhance communication among researchers, funding agencies, universities, and the general public â€" with the object of stimulating interdisciplinary research at the most exciting frontiers. The Futures Initiative builds on three pillars of vital and sustained research: interdisciplinary encounters that counterbalance specialization and isolation; the identification and exploration of new research topics; and communication that bridges languages, cultures, habits of thought, and institutions. Toward these goals, the National Academies Keck Futures Initiative incorporates three core activities each year: Futures conferences, Futures grants, and National Academies Communication Awards.

Organ-on-a-chip

Organ-on-a-chip
Author: Julia Hoeng,David Bovard,Manuel C. Peitsch
Publsiher: Academic Press
Total Pages: 546
Release: 2019-11-09
ISBN 10: 0128172037
ISBN 13: 9780128172032
Language: EN, FR, DE, ES & NL

Organ-on-a-chip Book Review:

Organ-on-a-Chip: Engineered Microenvironments for Safety and Efficacy Testing contains chapters from world-leading researchers in the field of organ on a chip development and applications, with perspectives from life sciences, medicine, physiology and engineering. The book contains an overview of the field, with sections covering the major organ systems and currently available technologies, platforms and methods. As readers may also be interested in creating biochips, materials and engineering best practice, these topics are also described. Users will learn about the limitations of 2D in-vitro models and the available 3D in-vitro models (what benefits they offer and some examples). Finally, the MOC section shows how the organ on a chip technology can be adapted to improve the physiology of in-vitro models. Includes case studies of other organs on a chip that have been developed and successfully used Provides insights into functional microphysiological organ on a chip platforms for toxicity and efficacy testing, along with opportunities for translational medicine Presented fields (PK/PD, physiology, medicine, safety) are given a definition followed by the challenges and potential of organs on a chip

Characterization and Development of Biosystems and Biomaterials

Characterization and Development of Biosystems and Biomaterials
Author: Andreas Öchsner,Lucas F. M. da Silva,Holm Altenbach
Publsiher: Springer Science & Business Media
Total Pages: 254
Release: 2012-12-16
ISBN 10: 3642314708
ISBN 13: 9783642314704
Language: EN, FR, DE, ES & NL

Characterization and Development of Biosystems and Biomaterials Book Review:

This collection of recent activities provides researchers and scientists with the latest trends in characterization and developments of biosystems and biomaterials. Well known experts present their research in materials for drug delivery, dental implants and filling materials, biocompatible membranes, bioactive surface coatings and bio-compatible and eco-sustainable building materials. In The book covers also topics like microorganisms, the human eye, the musculoskeletal system and human body parts.

Tissue Engineering

Tissue Engineering
Author: Clemens Van Blitterswijk,Jan De Boer
Publsiher: Academic Press
Total Pages: 896
Release: 2014-12-10
ISBN 10: 0124202101
ISBN 13: 9780124202108
Language: EN, FR, DE, ES & NL

Tissue Engineering Book Review:

Tissue Engineering is a comprehensive introduction to the engineering and biological aspects of this critical subject. With contributions from internationally renowned authors, it provides a broad perspective on tissue engineering for students coming to the subject for the first time. In addition to the key topics covered in the previous edition, this update also includes new material on the regulatory authorities, commercial considerations as well as new chapters on microfabrication, materiomics and cell/biomaterial interface. Effectively reviews major foundational topics in tissue engineering in a clear and accessible fashion Includes state of the art experiments presented in break-out boxes, chapter objectives, chapter summaries, and multiple choice questions to aid learning New edition contains material on regulatory authorities and commercial considerations in tissue engineering

Principles of Tissue Engineering

Principles of Tissue Engineering
Author: Robert Lanza,Robert Langer,Joseph P. Vacanti
Publsiher: Elsevier
Total Pages: 995
Release: 2000-05-16
ISBN 10: 008053967X
ISBN 13: 9780080539676
Language: EN, FR, DE, ES & NL

Principles of Tissue Engineering Book Review:

The opportunity that tissue engineering provides for medicine is extraordinary. In the United States alone, over half-a-trillion dollars are spent each year to care for patients who suffer from tissue loss or dysfunction. Although numerous books and reviews have been written on tissue engineering, none has been as comprehensive in its defining of the field. Principles of Tissue Engineering combines in one volume the prerequisites for a general understanding of tissue growth and development, the tools and theoretical information needed to design tissues and organs, as well as a presentation of applications of tissue engineering to diseases affecting specific organ systems. The first edition of the book, published in 1997, is the definite reference in the field. Since that time, however, the discipline has grown tremendously, and few experts would have been able to predict the explosion in our knowledge of gene expression, cell growth and differentiation, the variety of stem cells, new polymers and materials that are now available, or even the successful introduction of the first tissue-engineered products into the marketplace. There was a need for a new edition, and this need has been met with a product that defines and captures the sense of excitement, understanding and anticipation that has followed from the evolution of this fascinating and important field. Key Features * Provides vast, detailed analysis of research on all of the major systems of the human body, e.g., skin, muscle, cardiovascular, hematopoietic, and nerves * Essential to anyone working in the field * Educates and directs both the novice and advanced researcher * Provides vast, detailed analysis of research with all of the major systems of the human body, e.g. skin, muscle, cardiovascular, hematopoietic, and nerves * Has new chapters written by leaders in the latest areas of research, such as fetal tissue engineering and the universal cell * Considered the definitive reference in the field * List of contributors reads like a "who's who" of tissue engineering, and includes Robert Langer, Joseph Vacanti, Charles Vacanti, Robert Nerem, A. Hari Reddi, Gail Naughton, George Whitesides, Doug Lauffenburger, and Eugene Bell, among others

Stem Cells

Stem Cells
Author: Christine Mummery,Anja van de Stolpe,Bernard Roelen,Hans Clevers
Publsiher: Academic Press
Total Pages: 448
Release: 2014-05-23
ISBN 10: 0124115675
ISBN 13: 9780124115675
Language: EN, FR, DE, ES & NL

Stem Cells Book Review:

The second edition of Stem Cells: Scientific Facts and Fiction provides the non-stem cell expert with an understandable review of the history, current state of affairs, and facts and fiction of the promises of stem cells. Building on success of its award-winning preceding edition, the second edition features new chapters on embryonic and iPS cells and stem cells in veterinary science and medicine. It contains major revisions on cancer stem cells to include new culture models, additional interviews with leaders in progenitor cells, engineered eye tissue, and xeno organs from stem cells, as well as new information on "organs on chips" and adult progenitor cells. In the past decades our understanding of stem cell biology has increased tremendously. Many types of stem cells have been discovered in tissues that everyone presumed were unable to regenerate in adults, the heart and the brain in particular. There is vast interest in stem cells from biologists and clinicians who see the potential for regenerative medicine and future treatments for chronic diseases like Parkinson's, diabetes, and spinal cord lesions, based on the use of stem cells; and from entrepreneurs in biotechnology who expect new commercial applications ranging from drug discovery to transplantation therapies. Explains in straightforward, non-specialist language the basic biology of stem cells and their applications in modern medicine and future therapy Includes extensive coverage of adult and embryonic stem cells both historically and in contemporary practice Richly illustrated to assist in understanding how research is done and the current hurdles to clinical practice

Biomaterials- and Microfluidics-Based Tissue Engineered 3D Models

Biomaterials- and Microfluidics-Based Tissue Engineered 3D Models
Author: J. Miguel Oliveira,Rui L. Reis
Publsiher: Springer Nature
Total Pages: 175
Release: 2020-04-13
ISBN 10: 3030365883
ISBN 13: 9783030365882
Language: EN, FR, DE, ES & NL

Biomaterials- and Microfluidics-Based Tissue Engineered 3D Models Book Review:

This contributed volume reviews the latest advances on relevant 3D tissue engineered in vitro models of disease making use of biomaterials and microfluidics. The main focus of this book is on advanced biomaterials and microfluidics technologies that have been used in in vitro mimetic 3D models of human diseases and show great promise in revolutionizing personalized medicine. Readers will discover important topics involving biomaterials and microfluidics design, advanced processing techniques, and development and validation of organ- and body-on-a-chip models for bone, liver, and cancer research. An in depth discussion of microfabrication methods for microfluidics development is also provided. This work is edited by two truly multidisciplinary scientists and includes important contributions from well-known experts in their fields. The work is written for both early stage and experienced researchers, and well-established scientists enrolled in the fields of biomaterials, microfluidics, and tissue engineering, and is especially suited to those who wish to become acquainted with the principles and latest developments of in vitro models of diseases, such as professionals working in pharma, medicine, and engineering.

"Poem to my Litter" by Max Ritvo. An Analysis about Laboratory Mice and their Misuse

Author: Rashida Thielhorn
Publsiher: GRIN Verlag
Total Pages: 5
Release: 2019-03-26
ISBN 10: 3668907536
ISBN 13: 9783668907539
Language: EN, FR, DE, ES & NL

"Poem to my Litter" by Max Ritvo. An Analysis about Laboratory Mice and their Misuse Book Review:

Essay from the year 2018 in the subject American Studies - Literature, grade: 2,3, University of Frankfurt (Main), language: English, abstract: Nowadays experimenting with and especially on animals seems to be the norm not everyone likes to discuss about: Animals like mice, dogs, cats, monkeys, fish, guinea pigs and rats are used in laboratories to develop general biological and anatomical knowledge, verify chemical substances, test make up products (outside Germany), or even test new medicines and drugs to calculate the consequences for human beings, who have a similar DNA structure. The used animals differ from their free relatives as laboratory rodents are bred to have the characteristics they need to serve society and fulfill their morally questionable purpose. Three million laboratory animals have to die yearly as a consequence of experiments in Germany. The number is far less then the number of slaughtered animals, who die for the meat production. In 2015 1.2 million people demonstrated in front of the EU Parliament; not to intensify the Prevention of Cruelty to Animals Act but to finally stop experimenting on animals. In other countries of the world, for example the USA, well-known organizations like PETA fight to stop animal-testing.

Microfluidic Cell Culture Systems

Microfluidic Cell Culture Systems
Author: Christopher Bettinger,Jeffrey T Borenstein,Sarah L Tao
Publsiher: William Andrew
Total Pages: 452
Release: 2012-12-31
ISBN 10: 143773460X
ISBN 13: 9781437734607
Language: EN, FR, DE, ES & NL

Microfluidic Cell Culture Systems Book Review:

The fields of microfluidics and BioMEMS are significantly impacting cell biology research and applications through the application of engineering solutions to human disease and health problems. The dimensions of microfluidic channels are well suited to the physical scale of biological cells, and the many advantages of microfluidics make it an attractive platform for new techniques in biology. This new professional reference applies the techniques of microsystems to cell culture applications. The authors provide a thoroughly practical guide to the principles of microfluidic device design and operation and their application to cell culture techniques. The resulting book is crammed with strategies and techniques that can be immediately deployed in the lab. Equally, the insights into cell culture applications will provide those involved in traditional microfluidics and BioMEMS with an understanding of the specific demands and opportunities presented by biological applications. The goal is to guide new and interested researchers and technology developers to the important areas and state-of-the-practice strategies that will enhance the efficiency and value of their technologies, devices and biomedical products. Provides insights into the design and development of microfluidic systems with a specific focus on cell culture applications Focuses on strategies and techniques for the design and fabrication of microfluidic systems and devices for cell culture Provides balanced coverage of microsystems engineering and bioengineering

Biomedical Engineering: Frontier Research and Converging Technologies

Biomedical Engineering: Frontier Research and Converging Technologies
Author: Hanjoong Jo,Ho-Wook Jun,Jennifer Shin,SangHoon Lee
Publsiher: Springer
Total Pages: 511
Release: 2015-07-23
ISBN 10: 3319218131
ISBN 13: 9783319218137
Language: EN, FR, DE, ES & NL

Biomedical Engineering: Frontier Research and Converging Technologies Book Review:

This book provides readers with an integrative overview of the latest research and developments in the broad field of biomedical engineering. Each of the chapters offers a timely review written by leading biomedical engineers and aims at showing how the convergence of scientific and engineering fields with medicine has created a new basis for practically solving problems concerning human health, wellbeing and disease. While some of the latest frontiers of biomedicine, such as neuroscience and regenerative medicine, are becoming increasingly dependent on new ideas and tools from other disciplines, the paradigm shift caused by technological innovations in the fields of information science, nanotechnology, and robotics is opening new opportunities in healthcare, besides dramatically changing the ways we actually practice science. At the same time, a new generation of engineers, fluent in many different scientific “languages,” is creating entirely new fields of research that approach the “old” questions from a new and holistic angle. The book reports on the scientific revolutions in the field of biomedicine by describing the latest technologies and findings developed at the interface between science and engineering. It addresses students, fellows, and faculty and industry investigators searching for new challenges in the broad biomedical engineering fields.

Biomaterials for Organ and Tissue Regeneration

Biomaterials for Organ and Tissue Regeneration
Author: Nihal Vrana,Helena Knopf-Marques,Julien Barthes
Publsiher: Woodhead Publishing
Total Pages: 846
Release: 2020-03-20
ISBN 10: 0081029071
ISBN 13: 9780081029077
Language: EN, FR, DE, ES & NL

Biomaterials for Organ and Tissue Regeneration Book Review:

Biomaterials for Organ and Tissue Regeneration: New Technologies and Future Prospects examines the use of biomaterials in applications related to artificial tissues and organs. With a strong focus on fundamental and traditional tissue engineering strategies, the book also examines how emerging and enabling technologies are being developed and applied. Sections provide essential information on biomaterial, cell properties and cell types used in organ generation. A section on state-of-the-art in organ regeneration for clinical purposes is followed by a discussion on enabling technologies, such as bioprinting, on chip organ systems and in silico simulations. Provides a systematic overview of the field, from fundamentals, to current challenges and opportunities Encompasses the classic paradigm of tissue engineering for creation of new functional tissue Discusses enabling technologies such as bioprinting, organ-on-chip systems and in silico simulations

Principles of Regenerative Medicine

Principles of Regenerative Medicine
Author: Anthony Atala,Robert Lanza,James A. Thomson,Robert Nerem
Publsiher: Academic Press
Total Pages: 1202
Release: 2010-12-16
ISBN 10: 9780123814234
ISBN 13: 0123814235
Language: EN, FR, DE, ES & NL

Principles of Regenerative Medicine Book Review:

Virtually any disease that results from malfunctioning, damaged, or failing tissues may be potentially cured through regenerative medicine therapies, by either regenerating the damaged tissues in vivo, or by growing the tissues and organs in vitro and implanting them into the patient. Principles of Regenerative Medicine discusses the latest advances in technology and medicine for replacing tissues and organs damaged by disease and of developing therapies for previously untreatable conditions, such as diabetes, heart disease, liver disease, and renal failure. Key for all researchers and instituions in Stem Cell Biology, Bioengineering, and Developmental Biology The first of its kind to offer an advanced understanding of the latest technologies in regenerative medicine New discoveries from leading researchers on restoration of diseased tissues and organs

Biomimetic Microengineering

Biomimetic Microengineering
Author: Hyun Jung Kim
Publsiher: CRC Press
Total Pages: 380
Release: 2020-02-05
ISBN 10: 1000725804
ISBN 13: 9781000725803
Language: EN, FR, DE, ES & NL

Biomimetic Microengineering Book Review:

This book will examine the relevant biological subjects involved in biomimetic microengineering as well as the design and implementation methods of such engineered microdevices. Physiological topics covered include regeneration of complex responses of our body on a cellular, tissue, organ, and inter-organ level. Technological concepts in cell and tissue engineering, stem cell biology, microbiology, biomechanics, materials science, micro- and nanotechnology, and synthetic biology are highlighted to increase understanding of the transdisciplinary methods used to create the more complex, robust biomimetic engineered models. The effectiveness of the new bioinspired microphysiological systems as replacements for existing in vitro or in vivo models is explained through sections that include the protocols to reconstitute three-dimensional (3D) structures, recapitulate physiological functions, and emulate the pathophysiology of human diseases. This book will also discuss how researchers can discover bridge technologies for disease modeling and personalized precision medicine. Features Focuses on cutting edge technologies that enable manipulation of living systems in a spatiotemporal manner. Incorporates research on reverse engineering of comples microenvironmental factors in human diseases. Highlights technologies related to patient-specific personalized medicine and their potential uses. Written by chapter authors who are highly respected researchers in science and engineering. Includes extensive references at the end of each chapter to enhance further study. Hyun Jung Kim is an Assistant Professor in the Department of Biomedical Engineering at The University of Texas at Austin. After receiving hois Ph.D. degree at Yonsei University in the Republic of Korea, he did extensive postdctoral research at both the University of Chicago and the Wyss Institute at Harvard University. These efforts resulted in cutting-edge breakthroughs in synthetic microbial community research and organomimetic human Gut-on-a-Chip microsystem. His research on Gut-on-a-Chip technology leads to the creation of a microfluidic device that mimics the physiology and pathology of the living human intestine. Since 2015, he has explored novel human host-microbiome ecosystems to discover the disease mechanism and new therapeutics in inflammatory bowel disease and colorectal cancers at UT Austin. In collaboration with clinicians, his lab is currently developing disease-oriented, patient-specific models for the advancement in pharmaceutical and clinical fields. • Focuses on cutting edge technologies that enable manipulation of living systems in a spatiotemporal manner. • Incorporates research on reverse engineering of complex microenvironmental factors in human diseases. • Highlights technologies related to patient-specific personalized medicine and their potential uses. • Written by chapter authors who are highly respected researchers in science and engineering. • Includes extensive references at the end of each chapter to enhance further study. Hyun Jung Kim is an Assistant Professor in the Department of Biomedical Engineering at The University of Texas at Austin. After receiving his Ph.D. degree at Yonsei University in the Republic of Korea, he did extensive postdoctoral research at both the University of Chicago and the Wyss Institute at Harvard University. These efforts resulted in cutting-edge breakthroughs in synthetic microbial community research and organomimetic human Gut-on-a-Chip microsystem. His research on Gut-on-a-Chip technology leads to the creation of a microfluidic device that mimics the physiology and pathology of the living human intestine. Since 2015, he has explored novel human host-microbiome ecosystems to discover the disease mechanism and new therapeutics in inflammatory bowel disease and colorectal cancer at UT Austin. In collaboration with clinicians, his lab is currently developing disease-oriented, patient-specific models for the advancement in pharmaceutical and clinical fields.

Lab-on-a-Chip Devices and Micro-Total Analysis Systems

Lab-on-a-Chip Devices and Micro-Total Analysis Systems
Author: Jaime Castillo-León,Winnie E. Svendsen
Publsiher: Springer
Total Pages: 243
Release: 2014-11-05
ISBN 10: 3319086871
ISBN 13: 9783319086873
Language: EN, FR, DE, ES & NL

Lab-on-a-Chip Devices and Micro-Total Analysis Systems Book Review:

This book covers all the steps in order to fabricate a lab-on-a-chip device starting from the idea, the design, simulation, fabrication and final evaluation. Additionally, it includes basic theory on microfluidics essential to understand how fluids behave at such reduced scale. Examples of successful histories of lab-on-a-chip systems that made an impact in fields like biomedicine and life sciences are also provided. This book also: · Provides readers with a unique approach and toolset for lab-on-a-chip development in terms of materials, fabrication techniques, and components · Discusses novel materials and techniques, such as paper-based devices and synthesis of chemical compounds on-chip · Covers the four key aspects of development: basic theory, design, fabrication, and testing · Provides readers with a comprehensive list of the most important journals, blogs, forums, and conferences where microfluidics and lab-on-a-chip news, methods, techniques and challenges are presented and discussed, as well as a list of companies providing design and simulation support, components, and/or developing lab-on-a-chip and microfluidic devices.

3D Printing Technology in Nanomedicine

3D Printing Technology in Nanomedicine
Author: Nabeel Ahmad,P. Gopinath,Rajiv Dutta
Publsiher: Elsevier
Total Pages: 202
Release: 2019-03-30
ISBN 10: 0128158913
ISBN 13: 9780128158913
Language: EN, FR, DE, ES & NL

3D Printing Technology in Nanomedicine Book Review:

3D Printing Technology in Nanomedicine provides an integrated and introductory look into the rapidly evolving field of nanobiotechnology. It demystifies the processes of commercialization and discusses legal and regulatory considerations. With a focus on nanoscale processes and biomedical applications, users will find this to be a comprehensive resource on how 3D printing can be utilized in a range of areas, including the diagnosis and treatment of a variety of human diseases. Examines the emerging market of 3D-printed biomaterials and their clinical applications, with a particular focus on both commercial and premarket tools Examines the promising market of 3D-printed nanoparticles, nanomaterial, biomaterials, composite nanomaterial and their clinical applications in the cardiovascular and chemotherapy realms Develops the concept of integrating different technologies along the hierarchical structure of biological systems

Open-Space Microfluidics

Open-Space Microfluidics
Author: Emmanuel Delamarche,Govind V. Kaigala
Publsiher: John Wiley & Sons
Total Pages: 450
Release: 2018-01-18
ISBN 10: 3527696792
ISBN 13: 9783527696796
Language: EN, FR, DE, ES & NL

Open-Space Microfluidics Book Review:

Summarizing the latest trends and the current state of this research field, this up-to-date book discusses in detail techniques to perform localized alterations on surfaces with great flexibility, including microfluidic probes, multifunctional nanopipettes and various surface patterning techniques, such as dip pen nanolithography. These techniques are also put in perspective in terms of applications and how they can be transformative of numerous (bio)chemical processes involving surfaces. The editors are from IBM Zurich, the pioneers and pacesetters in the field at the forefront of research in this new and rapidly expanding area.