Principles and Practice of Clinical Research

Principles and Practice of Clinical Research
Author: John I. Gallin,Frederick P Ognibene,Laura Lee Johnson
Publsiher: Academic Press
Total Pages: 824
Release: 2017-11-17
ISBN 10: 0128499044
ISBN 13: 9780128499047
Language: EN, FR, DE, ES & NL

Principles and Practice of Clinical Research Book Review:

Principles and Practice of Clinical Research, Fourth Edition has been thoroughly revised to provide a comprehensive look at both the fundamental principles and expanding practice of clinical research. New to this edition of this highly regarded reference, authors have focused on examples that broadly reflect clinical research on a global scale while including a discussion of international regulations, studies, and implications. In addition to key topics such as bioethics, clinical outcome data, cultural diversity, protocol guidelines, and “omic platforms, this edition contains new chapters devoted to electronic health records and information resources for clinical researchers, as well as the many opportunities associated with big data. Covering a vast number of topics and practical advice for both novice and advanced clinical investigators, this book is a highly relevant and essential resource for all those involved in conducting research. Features input from experts in the field dedicated to translating scientific research from bench to bedside and back Provides expanded coverage of global clinical research Contains hands-on, practical suggestions, illustrations, and examples throughout Includes new chapters on the international regulation of drugs and biologics, the emergence of the important role of comparative effectiveness research and how to identify clinical risks and manage patient safety in a clinical research setting

Principles and Practice of Clinical Trial Medicine

Principles and Practice of Clinical Trial Medicine
Author: Richard Chin,Bruce Y Lee
Publsiher: Elsevier
Total Pages: 560
Release: 2008-07-25
ISBN 10: 9780080557939
ISBN 13: 0080557937
Language: EN, FR, DE, ES & NL

Principles and Practice of Clinical Trial Medicine Book Review:

Clinical trials are an important part of medicine and healthcare today, deciding which treatments we use to treat patients. Anyone involved in healthcare today must know the basics of running and interpreting clinical trial data. Written in an easy-to-understand style by authors who have considerable expertise and experience in both academia and industry, Principles and Practice of Clinical Trial Medicine covers all of the basics of clinical trials, from legal and ethical issues to statistics, to patient recruitment and reporting results. Jargon-free writing style enables those with less experience to run their own clinical trials and interpret data Book contains an ideal mix of theory and practice so researchers will understand both the rationale and logistics to clinical trial medicine Expert authorship whose experience includes running clinical trials in an academic as well as industry settings Numerous illustrations reinforce and elucidate key concepts and add to the book's overall pedagogy

Principles and Practice of Clinical Trials

Principles and Practice of Clinical Trials
Author: Steven Piantadosi,Curtis L. Meinert
Publsiher: Springer
Total Pages: 329
Release: 2022-02-27
ISBN 10: 9783319526355
ISBN 13: 3319526359
Language: EN, FR, DE, ES & NL

Principles and Practice of Clinical Trials Book Review:

This is a comprehensive major reference work for our SpringerReference program covering clinical trials. Although the core of the Work will focus on the analysis and interpretation of scientific data gleaned from the trial process, a broad spectrum of clinical trial principles and practice areas will be covered in detail. This is an important time to develop such a Work, as drug safety and efficacy cannot be guaranteed and regulated without the Clinical Trials process. Because of an immense and continuing to grow international disease burden, pharmaceutical and biotechnology companies continue to develop new drugs. Clinical trials have also become extremely globalized in the past 15 years, with over 225,000 international trials ongoing at this point in time. Principles in Practice of Clinical Trials is truly an interdisciplinary that will be divided into the following areas: 1) Clinical Trials Basic Perspectives2) Regulation and Oversight3) Basic Trial Designs4) Advanced Trial Designs5) Analysis6) Trial Publication7) Topics Related Specific Populations and Legal Aspects of Clinical Trials The Work is designed to be comprised of 175 chapters and approximately 2500 pages. The Work will be oriented like many of our SpringerReference Handbooks, presenting detailed and comprehensive expository chapters on broad subjects. The Editors are major figures in the field of clinical trials, and both have written textbooks on the topic. There will also be a slate of 7-8 renowned associate editors that will edit individual sections of the Reference.

Critical Thinking in Clinical Research

Critical Thinking in Clinical Research
Author: Felipe Fregni,Ben M. W. Illigens
Publsiher: Oxford University Press
Total Pages: 518
Release: 2018
ISBN 10: 0199324492
ISBN 13: 9780199324491
Language: EN, FR, DE, ES & NL

Critical Thinking in Clinical Research Book Review:

Critical Thinking in Clinical Research explains the fundamentals of clinical research in a case-based approach. The core concept is to combine a clear and concise transfer of information and knowledge with an engagement of the reader to develop a mastery of learning and critical thinking skills. The book addresses the main concepts of clinical research, basics of biostatistics, advanced topics in applied biostatistics, and practical aspects of clinical research, with emphasis on clinical relevance across all medical specialties.

Principles of Good Clinical Practice

Principles of Good Clinical Practice
Author: Michael J. McGraw,Shawn P. Shearn
Publsiher: Pharmaceutical Press
Total Pages: 256
Release: 2010
ISBN 10: 0853697906
ISBN 13: 9780853697909
Language: EN, FR, DE, ES & NL

Principles of Good Clinical Practice Book Review:

This text aims to be a one-stop source for guidance and checking the rules for proper conduct of clinical trials, as well as providing a historical perspective of the clinical research landscape. Good Clinical Practice guidelines provide an international quality standard for the regulation of clinical trials. They include standards on how clinical trials should be conducted, provide assurance of safety and efficacy of newly developed drugs and protect human rights. Principles of Good Clinical Practice describes the ethical principles and regulatory requirements that influence the current and future conduct of clinical research. As well as providing essential information on clinical trial design and pharmacovigilance, coverage also includes: informed consent; investigator and sponsor responsibilities; site monitoring; institutional review boards and dependent ethics committees; clinical trial registration and reporting; quality assurance; and future implications for good clinical practices. Principles of Good Clinical Practice will be a definitive text for Clinical Development personnel at pharmaceutical companies, Contract Research Organizations (CROs), PharmD and postgraduate pharmacy students, and medical, pharmacy and drug company libraries

Principles and Practice of Clinical Electrophysiology of Vision

Principles and Practice of Clinical Electrophysiology of Vision
Author: John R. Heckenlively,Geoffrey Bernard Arden,Steven Nusinowitz,Graham E. Holder,Michael Bach
Publsiher: MIT Press
Total Pages: 977
Release: 2006
ISBN 10: 0262083469
ISBN 13: 9780262083461
Language: EN, FR, DE, ES & NL

Principles and Practice of Clinical Electrophysiology of Vision Book Review:

40 Early Receptor Potential

Clinical Research

Clinical Research
Author: Manfred Stommel,Celia Wills
Publsiher: Lippincott Williams & Wilkins
Total Pages: 462
Release: 2004
ISBN 10: 9780781735186
ISBN 13: 0781735181
Language: EN, FR, DE, ES & NL

Clinical Research Book Review:

This unique textbook integrates statistical concepts into evidence-based clinical practice and patient management. Research concepts and techniques are drawn from epidemiology, bio-statistics, and psychometrics, as well as educational and social science research. Clinical examples throughout the text illustrate practical and scientifically sound applications of the concepts. Data tables and research vignettes highlight statistical distributions involving probability. Methods to locate and utilize web-based information relevant to clinical research are discussed, and web URLs are provided. Further learning is encouraged by the inclusion of suggested activities, recommended readings, references, and a comprehensive glossary of research terms. Additional resources are available at a Connection Website, connection.LWW.com/go/stommel.

Clinical Trials

Clinical Trials
Author: Stuart J. Pocock
Publsiher: John Wiley & Sons
Total Pages: 288
Release: 2013-07-17
ISBN 10: 1118794109
ISBN 13: 9781118794104
Language: EN, FR, DE, ES & NL

Clinical Trials Book Review:

This comprehensive, unified text on the principles and practice of clinical trials presents a detailed account of how to conduct the trials. It describes the design, analysis, and interpretation of clinical trials in a non-technical manner and provides a general perspective on their historical development, current status, and future strategy. Features examples derived from the author's personal experience.

Principles and Practice of Research in Midwifery E Book

Principles and Practice of Research in Midwifery E Book
Author: Elizabeth R. Cluett,Rosalind Bluff
Publsiher: Elsevier Health Sciences
Total Pages: 308
Release: 2006-05-03
ISBN 10: 0702035181
ISBN 13: 9780702035180
Language: EN, FR, DE, ES & NL

Principles and Practice of Research in Midwifery E Book Book Review:

This title is directed primarily towards health care professionals outside of the United States. Written by authors with clinical and research experience, this book is intended for midwives and student midwives participating in Diploma, Advanced Diploma and first level degree programmes. It aims to increase research awareness and develop the skills of critical appraisal of research evidence that are essential to evidence based practice.

Principles and Practice of Clinical Parasitology

Principles and Practice of Clinical Parasitology
Author: Stephen Gillespie,Richard D. Pearson
Publsiher: John Wiley & Sons
Total Pages: 680
Release: 2003-01-24
ISBN 10: 0470851724
ISBN 13: 9780470851722
Language: EN, FR, DE, ES & NL

Principles and Practice of Clinical Parasitology Book Review:

A comprehensive account of protozoan and metozoan diseases in modern clinical practice, with orientation towards clinical management of parasitic infections. In the past, parasitology was considered as an obscure subject of little relevance to the majority of clinicians and microbiologists. Over the last decade, however, much has happened to change this, not least the explosion in foreign travel This textbook is the forth in the Principles and Practice series, providing an expansive and detailed coverage of clinical microbiology. It has a similar appeal to that of Zuckerman's, Principles & Practice of Clinical Virology, with an international authorship and emphasis placed on integrating new knowledge in a clinically relevant manner. . An essential, up-to-date sourcebook on the fundamentals of human parasitology . Provides a global approach with renowned and international authorship . Completes the quartet of Principles and Practice series in Microbiology

Principles and Practice of Research

Principles and Practice of Research
Author: H. Troidl,W.O. Spitzer,B. McPeek,D.S. Mulder,Martin F. Bach
Publsiher: Springer Science & Business Media
Total Pages: 381
Release: 2012-12-06
ISBN 10: 3642969429
ISBN 13: 9783642969423
Language: EN, FR, DE, ES & NL

Principles and Practice of Research Book Review:

emerging on the surgical scene to challenge or For some readers, the title of this book will im thodoxy. Although these innovations are often mediately raise the question, what exactly is greeted with great optimism, a factual basis for meant by surgical research? In the very broadest that enthusiasm is sometimes far from secure sense the term can be taken to include all en and much further work is frequently required to deavors, however elementary or limited in discover whether we are dealing with genuine scope, to advance surgical knowledge. Ideally, advances or not. it refers to well-organized attempts to establish The most exciting and attractive scenario for on a proper scientific basis, i. e. , to place beyond surgical research is unquestionably one that de reasonable doubt, the truth or otherwise of any picts a successful attempt by a researcher to es concepts, old or new, within the ambit of sur gery, and, of course, anaesthesia. tablish the accuracy of some bold innovation for which he himself is responsible. Joseph Lister, The methods used to achieve that end vary demonstrating by clinical trial that wound sup enormously, depending on the issue being in vestigated.

Clinical Trials in Cancer

Clinical Trials in Cancer
Author: David J. Girling
Publsiher: Oxford University Press, USA
Total Pages: 367
Release: 2003
ISBN 10: 9780192629593
ISBN 13: 019262959X
Language: EN, FR, DE, ES & NL

Clinical Trials in Cancer Book Review:

Clinical Trials in Cancer provides concise, accessible and practical information on the practicalities of planning, designing, conducting, analysing, reporting, and interpreting phase III clinical trials predominantly, but also single-arm and randomized phase II trials. The book shows clearly how recent developments and current thinking can be implemented. Information on the need to decide and measure realistic target differences in trials, the conduct and interpretation of interim analyses, patient advocacy, good clinical practice, the study of quality of life, the role of meta-analyses, and informed consent and other ethical issues are also covered. DEGREESNL This book will prove invaluable for medical, statistical, and biological cancer researchers, health care professionals, and researchers in the pharmaceutical industry. Trial sponsors, principal investigators, members of data monitoring and trial supervisory committees, specialists invited to provide independent assessments, and many others involved in all aspects of research related to clinical trials should also find this book helpful.

Emery and Rimoin s Principles and Practice of Medical Genetics and Genomics

Emery and Rimoin   s Principles and Practice of Medical Genetics and Genomics
Author: Reed E. Pyeritz,Bruce R. Korf,Wayne W. Grody
Publsiher: Academic Press
Total Pages: 790
Release: 2020-09-30
ISBN 10: 0128126833
ISBN 13: 9780128126837
Language: EN, FR, DE, ES & NL

Emery and Rimoin s Principles and Practice of Medical Genetics and Genomics Book Review:

For decades, Emery and Rimoin’s Principles and Practice of Medical Genetics and Genomics has served as the ultimate resource for clinicians integrating genetics into medical practice. With nearly 5,000 pages of detailed coverage, contributions from over 250 of the world’s most trusted authorities in medical genetics, and a series of 11 volumes available for individual sale, the Seventh Edition of this classic reference includes the latest information on seminal topics such as prenatal diagnosis, genome and exome sequencing, public health genetics, genetic counseling, and management and treatment strategies to complete its coverage of this growing field for medical students, residents, physicians, and researchers involved in the care of patients with genetic conditions. This comprehensive yet practical resource emphasizes theory and research fundamentals related to applications of medical genetics across the full spectrum of inherited disorders and applications to medicine more broadly. In Metabolic Disorders, leading physicians and researchers thoroughly examine medical genetics as applied to a range of metabolic disorders, with emphasis on understanding the genetic mechanisms underlying these disorders, diagnostic approaches, and therapeutics that make use of current genomic technologies and translational studies. Here genetic researchers, students, and health professionals will find new and fully revised chapters on the genetic basis of body mass, amino acid, carbohydrate, iron, copper, lipo protein, and lipid metabolic disorders, as well as organic acidemias, fatty acid oxidation, and peroxisome disorders among others. With regular advances in genomic technologies propelling precision medicine into the clinic, Emery and Rimoin’s Principles and Practice of Medical Genetics and Genomics: Seventh Edition bridges the gap between high-level molecular genetics and practical application and serves as an invaluable clinical tool for health professionals and researchers. Wholly revised and up-to-date, this volume thoroughly addresses medical genetics and genomics as applied to metabolic disorders, with emphasis on understanding the genetic mechanisms underlying these disorders, diagnostic approaches, and treatment methods Provides genetic researchers, students, and health professionals with up-to-date coverage on the genetic basis of a range of metabolic disorders, including body mass, amino acid, carbohydrate, iron, copper, lipo protein, and lipid metabolic disorders, as well as organic acidemias, fatty acid oxidation, and peroxisome disorders among others Includes color images supporting identification, concept illustration, and method processing Features contributions by leading international researchers and practitioners of medical genetics A robust companion website offers lecture slides, image banks, and links to outside resources and articles to stay up-to-date on the latest developments in the field

Clinical Research and the Law

Clinical Research and the Law
Author: Patricia M. Tereskerz
Publsiher: John Wiley & Sons
Total Pages: 280
Release: 2012-04-24
ISBN 10: 1118272161
ISBN 13: 9781118272169
Language: EN, FR, DE, ES & NL

Clinical Research and the Law Book Review:

The legal implications of conducting clinical research and trials are becoming more complex. Everyone involved in clinical research increasingly needs to be aware of not only the ethical issues at stake but also how the law affects medical practice and research. Much of clinical research and trial law and litigation is comparatively recent and researchers need to ensure current compliance on a wide range of issues. Including: standards and duty of care informed consent conflicts of interest research contracts establishing clinical trials the disclosure and withholding of clinical trial results Clinical Research and the Law comprehensively discusses these topics and provides the answers to the legal questions and potential pitfalls encountered in medical research. It is an up-to-date, practical guide for clinical investigators and their institutional administrators, particularly risk managers and research administrators, as well as healthcare administrators and members of institutional review boards. This book is also a key resource for medical students, postgraduate research students, practicing attorneys and counselors for teaching hospitals and institutions undertaking clinical research and contract research organizations.

Clinical Trials

Clinical Trials
Author: Steven Piantadosi
Publsiher: John Wiley & Sons
Total Pages: 720
Release: 2013-05-29
ISBN 10: 1118625854
ISBN 13: 9781118625859
Language: EN, FR, DE, ES & NL

Clinical Trials Book Review:

Learn rigorous statistical methods to ensure valid clinicaltrials This Second Edition of the critically hailed Clinical Trials buildson the text's reputation as a straightforward and authoritativepresentation of statistical methods for clinical trials. Readersare introduced to the fundamentals of design for various types ofclinical trials and then skillfully guided through the completeprocess of planning the experiment, assembling a study cohort,assessing data, and reporting results. Throughout the process, theauthor alerts readers to problems that may arise during the courseof the trial and provides commonsense solutions. The author bases the revisions and updates on his own classroomexperience, as well as feedback from students, instructors, andmedical and statistical professionals involved in clinical trials.The Second Edition greatly expands its coverage, ranging fromstatistical principles to controversial topics, includingalternative medicine and ethics. At the same time, it offers morepragmatic advice for issues such as selecting outcomes, samplesize, analysis, reporting, and handling allegations of misconduct.Readers familiar with the First Edition will discover completelynew chapters, including: * Contexts for clinical trials * Statistical perspectives * Translational clinical trials * Dose-finding and dose-ranging designs Each chapter is accompanied by a summary to reinforce the keypoints. Revised discussion questions stimulate critical thinkingand help readers understand how they can apply their newfoundknowledge, and updated references are provided to direct readers tothe most recent literature. This text distinguishes itself with its accessible and broadcoverage of statistical design methods--the crucial building blocksof clinical trials and medical research. Readers learn to conductclinical trials that produce valid qualitative results backed byrigorous statistical methods.

Principles and Practice of Movement Disorders E Book

Principles and Practice of Movement Disorders E Book
Author: Stanley Fahn,Joseph Jankovic,Mark Hallett
Publsiher: Elsevier Health Sciences
Total Pages: 556
Release: 2011-08-09
ISBN 10: 1437737706
ISBN 13: 9781437737707
Language: EN, FR, DE, ES & NL

Principles and Practice of Movement Disorders E Book Book Review:

Principles and Practice of Movement Disorders provides the complete, expert guidance you need to diagnose and manage these challenging conditions. Drs. Stanley Fahn, Joseph Jankovic and Mark Hallett explore all facets of these disorders, including the latest rating scales for clinical research, neurochemistry, clinical pharmacology, genetics, clinical trials, and experimental therapeutics. This edition features many new full-color images, additional coverage of pediatric disorders, updated Parkinson information, and many other valuable updates. An accompanying Expert Consult website makes the content fully searchable and contains several hundred video clips that illustrate the manifestations of all the movement disorders in the book along with their differential diagnoses. Get just the information you need for a clinical approach to diagnosis and management, with minimal emphasis on basic science. Find the answers you need quickly and easily thanks to a reader-friendly full-color format, with plentiful diagrams, photographs, and tables. Apply the latest advances to diagnosis and treatment of pediatric movement disorders, Parkinson disease, and much more. View the characteristic presentation of each disorder with a complete collection of professional-quality, narrated videos online. Better visualize every concept with new full-color illustrations throughout. Search the complete text online, follow links to PubMed abstracts, and download all of the illustrations, at www.expertconsult.com.

Clinical Psychopharmacology

Clinical Psychopharmacology
Author: Nassir Ghaemi
Publsiher: Oxford University Press, USA
Total Pages: 600
Release: 2019-01-04
ISBN 10: 0199995486
ISBN 13: 9780199995486
Language: EN, FR, DE, ES & NL

Clinical Psychopharmacology Book Review:

Clinical Psychopharmacology offers a comprehensive guide to clinical practice that explores two major aspects of the field: the clinical research that exists to guide clinical practice of psychopharmacology, and the application of that knowledge with attention to the individualized aspects of clinical practice. The text consists of 50 chapters, organized into 6 sections, focusing on disease-modifying effects, non-DSM diagnostic concepts, and essential facts about the most common drugs. This innovative book advocates a scientific and humanistic approach to practice and examines not only the benefits, but also the harms of drugs. Providing a solid foundation of knowledge and a great deal of practical information, this book is a valuable resource for practicing psychiatrists, psychiatric nurse practitioners, medical students and trainees in psychiatry, as well as pharmacists.

Neuroepidemiology

Neuroepidemiology
Author: Lorene M. Nelson
Publsiher: Oxford University Press
Total Pages: 461
Release: 2004
ISBN 10: 019513379X
ISBN 13: 9780195133790
Language: EN, FR, DE, ES & NL

Neuroepidemiology Book Review:

This fine text provides a comprehensive overview of methods for epidemiologic and clinical research on neurological disorders. The book focuses on classic principles of study design in epidemiologic research, strategies for avoiding study biases, methods for conducting clinical trials and prognostic studies, and principles of evidence-based medicine in neurology. The text gives neurologists, epidemiologists, and their students the foundation for conducting rigorous epidemiologic and clinical research on neurologic disorders.

Conflict of Interest in Medical Research Education and Practice

Conflict of Interest in Medical Research  Education  and Practice
Author: Institute of Medicine,Board on Health Sciences Policy,Committee on Conflict of Interest in Medical Research, Education, and Practice
Publsiher: National Academies Press
Total Pages: 436
Release: 2009-09-16
ISBN 10: 0309145449
ISBN 13: 9780309145442
Language: EN, FR, DE, ES & NL

Conflict of Interest in Medical Research Education and Practice Book Review:

Collaborations of physicians and researchers with industry can provide valuable benefits to society, particularly in the translation of basic scientific discoveries to new therapies and products. Recent reports and news stories have, however, documented disturbing examples of relationships and practices that put at risk the integrity of medical research, the objectivity of professional education, the quality of patient care, the soundness of clinical practice guidelines, and the public's trust in medicine. Conflict of Interest in Medical Research, Education, and Practice provides a comprehensive look at conflict of interest in medicine. It offers principles to inform the design of policies to identify, limit, and manage conflicts of interest without damaging constructive collaboration with industry. It calls for both short-term actions and long-term commitments by institutions and individuals, including leaders of academic medical centers, professional societies, patient advocacy groups, government agencies, and drug, device, and pharmaceutical companies. Failure of the medical community to take convincing action on conflicts of interest invites additional legislative or regulatory measures that may be overly broad or unduly burdensome. Conflict of Interest in Medical Research, Education, and Practice makes several recommendations for strengthening conflict of interest policies and curbing relationships that create risks with little benefit. The book will serve as an invaluable resource for individuals and organizations committed to high ethical standards in all realms of medicine.

Understanding Clinical Research

Understanding Clinical Research
Author: Renato D. Lopes,Robert A. Harrington
Publsiher: McGraw Hill Professional
Total Pages: 272
Release: 2013-05-22
ISBN 10: 0071792651
ISBN 13: 9780071792653
Language: EN, FR, DE, ES & NL

Understanding Clinical Research Book Review:

A complete guide to understanding and applying clinical research results Ideal for both researchers and healthcare providers Understanding Clinical Research addresses both the operational challenges of clinical trials and the needs of clinicians to comprehend the nuances of research methods to accurately analyze study results. This timely resource covers all aspects of clinical trials--from study design and statistics to regulatory oversight--and it delivers a detailed yet streamlined overview of must-know research topics. The text features an accessible three-part organization that traces the evolution of clinical research and explains the bedrock principles and unique challenges of clinical experimentation and observational research. Reinforcing this content are real-life case examples--drawn from the authors' broad experience--that put chapter concepts into action and contribute to a working knowledge of integral research techniques. FEATURES: The most definitive guide to promoting excellence in clinical research, designed to empower healthcare providers to assess a study's strengths and weaknesses with confidence and apply this knowledge to optimize patient outcomes In-depth coverage of fundamental research methods and protocols from preeminent authorities provides readers with an instructive primer and a springboard for ongoing clinical research education Clear, comprehensive three-part organization: Section One: Evolution of Clinical Research offers a succinct history of clinical trials, drug regulations, and the role of the FDA while covering the impact of information technology and academic research organizations Section Two: Principles of Clinical Experimentation takes you through the typical phases of clinical trials in the development of medical products, from initial human subject research to postapproval surveillance studies Section Three: Observational Research highlights the underlying principles, pitfalls, and methods for case-control studies, cohort studies, registries, and subgroup analyses within randomized trials