Postmortem Toxicology of Abused Drugs

Postmortem Toxicology of Abused Drugs
Author: Steven B. Karch, MD, FFFLM
Publsiher: CRC Press
Total Pages: 216
Release: 2007-10-09
ISBN 10: 9781420054545
ISBN 13: 1420054546
Language: EN, FR, DE, ES & NL

Postmortem Toxicology of Abused Drugs Book Review:

Extracted from the Drug Abuse Handbook, 2nd edition, to give you just the information you need at an affordable price. Postmortem Toxicology of Abused Drugs considers the role of toxicology in the investigation of homicide, suicide, accident, natural death, and overdose. It gives practical insights and case reviews on conducting toxicology tests and completing toxicology reports. It explains chain of custody; specimen collection and security; sampling of blood, urine, bile, and vitreous humor; and the selection of post-mortem specimens. Analyzing various testing procedures, the book covers simple chemical tests, microdiffusion tests, chromatography, spectroscopy, and more. It also discusses methods and strategies for analysis; and covers quality assurance protocols and controls. To help avoid common pitfalls, the text demonstrates the proper interpretation of postmortem drug levels based on knowledge of pharmacokinetics, metabolism, and pharmacogenetics; post-mortem redistribution and diffusion; and other considerations such as synergistic toxicity, and drug instability. Heavily referenced and containing several tables, figures, and useful appendices, this book is a handy reference for forensic scientists and medical examiners involved with death investigation.

Postmortem Toxicology

Postmortem Toxicology
Author: Timothy P. Rohrig
Publsiher: Academic Press
Total Pages: 266
Release: 2019-02-22
ISBN 10: 0128151641
ISBN 13: 9780128151648
Language: EN, FR, DE, ES & NL

Postmortem Toxicology Book Review:

Postmortem Toxicology addresses the various aspects of the practice of forensic postmortem toxicology from a viewpoint of elements which must be taken into consideration for proper interpretation of the toxicological result, not in a vacuum but in a more holistic and global sense. The volume examines pre-analytical factors, storage containers/conditions, prior medical interventions and therapy, along with information from the scene investigation and anatomical findings. This reference also provides explanation of the complicating conditions for the interpretation of the toxicological results due to postmortem decomposition, embalming artifacts and the postmortem redistribution of drugs. Tolerance is also discussed as an aid to interpreting results from a habitual/chronic user of medications and/or drugs of abuse. The book is geared towards the current practitioner; however, it is written to be used as a valuable reference for a graduate or post-graduate level courses in forensic toxicology or forensic pathology. Presents a holistic approach to the interpretation of toxicology results Covers pre-analytical factors, storage containers/conditions, prior medical interventions, therapy, and much more Written for the current practitioner, but an excellent resource for graduate level students training in the field of forensic toxicology

Postmortem Toxicology

Postmortem Toxicology
Author: Burkhard Madea
Publsiher: Unknown
Total Pages: 158
Release: 2004
ISBN 10: 1928374650XXX
ISBN 13: OCLC:254995434
Language: EN, FR, DE, ES & NL

Postmortem Toxicology Book Review:

Principles of Forensic Toxicology

Principles of Forensic Toxicology
Author: Barry Levine
Publsiher: Amer. Assoc. for Clinical Chemistry
Total Pages: 385
Release: 2003
ISBN 10: 9781890883874
ISBN 13: 1890883875
Language: EN, FR, DE, ES & NL

Principles of Forensic Toxicology Book Review:

Distribution of Methadone and EDDP in Postmortem Toxicology Cases

Distribution of Methadone and EDDP in Postmortem Toxicology Cases
Author: Jessica Amanda Jennings
Publsiher: Unknown
Total Pages: 176
Release: 2005
ISBN 10: 1928374650XXX
ISBN 13: MSU:31293027361504
Language: EN, FR, DE, ES & NL

Distribution of Methadone and EDDP in Postmortem Toxicology Cases Book Review:

Interpretation of Postmortem Toxicology Results

Interpretation of Postmortem Toxicology Results
Author: Anna Koski
Publsiher: Unknown
Total Pages: 56
Release: 2005
ISBN 10: 9789521026621
ISBN 13: 9521026626
Language: EN, FR, DE, ES & NL

Interpretation of Postmortem Toxicology Results Book Review:

Postmortem Toxicology

Postmortem Toxicology
Author: Sarah R. Nelson
Publsiher: Unknown
Total Pages: 74
Release: 2006
ISBN 10: 1928374650XXX
ISBN 13: OCLC:83613342
Language: EN, FR, DE, ES & NL

Postmortem Toxicology Book Review:

Forensic Microbiology

Forensic Microbiology
Author: David O. Carter,Jeffery K. Tomberlin,M. Eric Benbow,Jessica L. Metcalf
Publsiher: John Wiley & Sons
Total Pages: 424
Release: 2017-03-27
ISBN 10: 1119062578
ISBN 13: 9781119062578
Language: EN, FR, DE, ES & NL

Forensic Microbiology Book Review:

Forensic Microbiology focuses on newly emerging areas of microbiology relevant to medicolegal and criminal investigations: postmortem changes, establishing cause of death, estimating postmortem interval, and trace evidence analysis. Recent developments in sequencing technology allow researchers, and potentially practitioners, to examine microbial communities at unprecedented resolution and in multidisciplinary contexts. This detailed study of microbes facilitates the development of new forensic tools that use the structure and function of microbial communities as physical evidence. Chapters cover: Experiment design Data analysis Sample preservation The influence of microbes on results from autopsy, toxicology, and histology Decomposition ecology Trace evidence This diverse, rapidly evolving field of study has the potential to provide high quality microbial evidence which can be replicated across laboratories, providing spatial and temporal evidence which could be crucial in a broad range of investigative contexts. This book is intended as a resource for students, microbiologists, investigators, pathologists, and other forensic science professionals.

Pilot reported Beta blockers Identified by Forensic Toxicology Analysis of Postmortem Specimens

Pilot reported Beta blockers Identified by Forensic Toxicology Analysis of Postmortem Specimens
Author: Dennis V. Canfield
Publsiher: Unknown
Total Pages: 10
Release: 2017
ISBN 10: 1928374650XXX
ISBN 13: OCLC:982195017
Language: EN, FR, DE, ES & NL

Pilot reported Beta blockers Identified by Forensic Toxicology Analysis of Postmortem Specimens Book Review:

"This study compared beta-blockers reported by pilots with the medications found by postmortem toxicology analysis of specimens received from fatal aviation accidents between 1999 and 2015. Several studies have compared drugs using the standard approach: Compare the drug found by toxicology analysis with the drug reported by the pilot. This study uniquely examined first the pilot-reported medication and then compared it to that detected by toxicology analysis. This study will serve two purposes: (1) determine the capability of a toxicology laboratory to detect reported medications, and (2) identify pilots with medications below detectable limits. Method: All information required for this study was extracted from the Toxicology Data Base system and was searched using ToxFlo or SQL Server Management Studio. The following information was collected and analyzed: pilot-reported trade and/or generic drug, date specimens received, time of accident, type of aviation operations (CFR), state, pilot level, age, class of medical, specimen type, specimen concentration, dose reported, frequency reported associated with the accident, quantity reported, National Transportation Safety Board (NTSB) accident event number, and all NTSB reports. Results: There were 319 pilots that either reported taking a beta-blocker or were found to be taking a beta-blocker by postmortem toxicology analysis. Metoprolol and Atenolol were the most commonly found beta-blockers (81%) in this study. Discussion: Time of death, therapeutic concentration, and specimen type were found to be factors in the ability of the laboratory to detect beta-blockers. Dose did not correlate with the ability of the toxicology laboratory to detect the beta-blocker. Conclusions: Beta-blockers taken by pilots will, in most cases, be found by a competent postmortem forensic toxicology laboratory at therapeutic concentrations. The dose taken by the pilot was not found to be a factor in the ability of the laboratory to identify beta-blockers. Time of dose, route of administration, specimen tested, and therapeutic concentration of the drug were found to be factors in the ability of the laboratory to identify beta-blockers in postmortem specimens taken from pilots that died in aviation accidents. 17. Key Words 18. Distribution Statement Toxicology, medications, drugs, aviation, safety, fatal, pilots Document is available."--Abstract.

Postmortem Toxicology

Postmortem Toxicology
Author: Per Holmgren,Universitetet i Linkzoping. Division of Clinical Pharmacology
Publsiher: Unknown
Total Pages: 61
Release: 2004
ISBN 10: 9789173738347
ISBN 13: 9173738344
Language: EN, FR, DE, ES & NL

Postmortem Toxicology Book Review:

Fundamentals of Analytical Toxicology

Fundamentals of Analytical Toxicology
Author: Robert J. Flanagan
Publsiher: John Wiley & Sons
Total Pages: 505
Release: 2007
ISBN 10: 0470319348
ISBN 13: 9780470319345
Language: EN, FR, DE, ES & NL

Fundamentals of Analytical Toxicology Book Review:

The analytical toxicologist may be required to detect, identify, and in many cases measure a wide variety of compounds in samples from almost any part of the body or in related materials such as residues in syringes or in soil. This book gives principles and practical information on the analysis of drugs and poisons in biological specimens, particularly clinical and forensic specimens. After providing some background information the book covers aspects of sample collection, transport, storage and disposal, and sample preparation. Analytical techniques - colour tests and spectrophotometry, chromatography and electro­phoresis, mass spectrometry, and immunoassay ? are covered in depth, and a chapter is devoted to the analysis of trace elements and toxic metals. General aspects of method implementation/validation and laboratory operation are detailed, as is the role of the toxicology laboratory in validating and monitoring the performance of point of care testing (POCT) devices. The book concludes with reviews of xenobiotic absorption, distribution and metabolism, pharmacokinetics, and general aspects of the interpretation of analytical toxicology results. A clearly written, practical, integrated approach to the basics of analytical toxicology. Focuses on analytical, statistical and pharmacokinetic principles rather than detailed applications. Assumes only a basic knowledge of analytical chemistry. An accompanying website provides additional material and links to related sites. Written by an experienced team of authors,Fundamentals of Analytical Toxicology is an invaluable resource for those starting out in a career in analytical toxicology across a wide range of disciplines including clinical and forensic science, food safety, and pharmaceutical development. Praise from the reviews: ?This is an ambitious effort to describe in detail the many and varied aspects of the science of toxicological analysis. The 17 chapters cover every foreseeable aspect, from specimen collection through analytical techniques and quality control to pharmacological principles and interpretation of results. The authors bring together a great deal of experience in the field and have succeeded admirably in achieving their goal: "to give principles and practical information on the analysis of drugs, poisons and other relevant analytes in biological specimens...". The book is very readable and quite up-to-date, and contains many illustrative figures, charts and tables. Both the student and the practicing professional would do well to study this material carefully, as there is something here for every conceivable level of interest.? Review from Randall Baselt "This text comes highly recommended for any analytical toxicology trainee." The Bulletin of the Royal College of Pathologists ?Overall, this book provides a comprehensive, thorough, clear, up to date and practical treatment of analytical toxicology at a high standard. Understanding of the text is enhanced by the use of many illustrations. Specifications, guidelines, and methods are highlighted in grey background ?Boxes?. The many and up to date literature references in each chapter demonstrate the authors? thorough work and permit easy access to deeper information. Therefore this book can be highly recommended as a valuable source of knowledge in analytical toxicology both as an introduction and for the advanced reader.? GTFCh Bulletin ?Toxichem + Krimtech?, May 2008 (translated, original review in German) ?Many toxicologists will add this important reference to their libraries because it competently fills a need ...? International Journal of Toxicology ?The book is very well illustrated, easy to understand and pleasant to read, and contains a wealth of dedicated information.? International Journal of Environmental Analytical Chemistry

Handbook of Forensic Toxicology for Medical Examiners

Handbook of Forensic Toxicology for Medical Examiners
Author: D. K. Molina, M.D.,Veronica Hargrove
Publsiher: CRC Press
Total Pages: 260
Release: 2018-06-13
ISBN 10: 1351260588
ISBN 13: 9781351260589
Language: EN, FR, DE, ES & NL

Handbook of Forensic Toxicology for Medical Examiners Book Review:

Forensic professionals, particularly medical examiners—often working through heavy caseloads—require quick and easy access to reliable sources of information to help interpret toxicology results. While several in-depth resources are available, they are often large, cumbersome, and contain more information than is often needed. The Handbook of Forensic Toxicology for Medical Examiners is a concise handbook referencing the most common toxic substances and their reported non-toxic, toxic, and lethal concentrations, making it an ideal text for quick reference in the lab or autopsy room. Features of the Second Edition: Explains the principles of postmortem toxicology and the factors which must be considered Provides tables of toxicologic data for over 200 commonly encountered substances, including drugs of abuse, poisons, prescription drugs, and over-the-counter medications Includes discussion and description of the novel psychoactive drugs—including synthetic opioids, cannabinoids, stimulants and hallucinogens Supplemental appendices provide additional information regarding specimen types and selection, testing methodologies, normal laboratory values, and conversion charts The busy forensic professional needs a concise handbook that provides critical information quickly and accurately. This heavily referenced text offers an easy-to-use format allowing for rapid access for both routine daily use and preparation for courtroom testimony.

Clarke s Analytical Forensic Toxicology

Clarke s Analytical Forensic Toxicology
Author: Gail Cooper,Adam Negrusz
Publsiher: Pharmaceutical Press
Total Pages: 656
Release: 2013-05-28
ISBN 10: 0857110543
ISBN 13: 9780857110541
Language: EN, FR, DE, ES & NL

Clarke s Analytical Forensic Toxicology Book Review:

This second edition of Clarke's Analytical Forensic Toxicology offers a fresh perspective on the drugs and poisons that you are most likely to encounter in forensic toxicology, with a focus on collection, extraction and analysis. With additional features incorporated from the fourth edition of Clarke's Analysis of Drugs and Poisons this text is fully updated to reflect the advances in analytical and forensic toxicology. New and extended chapters include: sampling, storage and stability; in-utero exposure to drugs of abuse; drug-facilitated sexual assault; and extraction. Providing unrivalled comprehensive coverage of analytical forensic toxicology, this book is a crucial resource for students of forensic science, toxicology, clinical pharmacology and analytical chemistry. It is an invaluable tool for teachers in these subject areas and a key resource for those working in forensic science laboratories.

Forensic Toxicology

Forensic Toxicology
Author: Max M. Houck
Publsiher: Academic Press
Total Pages: 418
Release: 2018-01-02
ISBN 10: 0128008180
ISBN 13: 9780128008188
Language: EN, FR, DE, ES & NL

Forensic Toxicology Book Review:

Forensic Toxicology, the latest release in the Advanced Forensic Science Series that grew out of recommendations from the 2009 NAS Report, Strengthening Forensic Science: A Path Forward will serve as a graduate level text for those studying and teaching forensic toxicology. It is also an excellent reference for the forensic practitioner’s library or for use in their casework. Coverage includes a wide variety of methods used, along with pharmacology and drugs and professional issues they may encounter. Edited by a world-renowned, leading forensic expert, this updated edition is a long overdue solution for the forensic science community. Provides basic principles of forensic science and an overview of forensic toxicology Contains information on a wide variety of methods Covers pharmacology and drugs, matrices and interpretation Includes a section on professional issues, such as crime scene to court, lab reports, health and safety, post-mortem and drug facilitated crimes Incorporates effective pedagogy, key terms, review questions, discussion questions and additional reading suggestions

The Second Seven Years of the FAA s Postmortem Forensic Toxicology Proficiency testing Program

The Second Seven Years of the FAA s Postmortem Forensic Toxicology Proficiency testing Program
Author: Arvind K. Chaturvedi
Publsiher: Unknown
Total Pages: 11
Release: 2008
ISBN 10: 1928374650XXX
ISBN 13: NWU:35556038310058
Language: EN, FR, DE, ES & NL

The Second Seven Years of the FAA s Postmortem Forensic Toxicology Proficiency testing Program Book Review:

"For aircraft accident investigations, samples from pilot fatalities are analyzed at the Federal Aviation Administration's (FAA's) Civil Aerospace Medical Institute (CAMI) for the presence of combustion gases, alcohols/volatiles, and drugs. Throughout this forensic toxicological process, a high degree of quality control/quality assurance (QC/QA) is maintained, and quality improvement is continuously pursued. Under this philosophy, CAMI started a quarterly forensic toxicology proficiency-testing (PT) program in July 1991 for the analysis of postmortem specimens. In continuation of the first 7 years of the CAMI PT findings reported earlier, PT findings of the next 7 years (July 1998-April 2005) are summarized herein."--P. i.

Toxicology Testing An Issue of Clinics in Laboratory Medicine E Book

Toxicology Testing  An Issue of Clinics in Laboratory Medicine   E Book
Author: Michael G. Bissell
Publsiher: Elsevier Health Sciences
Total Pages: 240
Release: 2012-09-24
ISBN 10: 1455747874
ISBN 13: 9781455747870
Language: EN, FR, DE, ES & NL

Toxicology Testing An Issue of Clinics in Laboratory Medicine E Book Book Review:

This issue of Clinics in Laboratory Medicine, titled Toxicology Testing, includes the following topics; Progress in Clinical Toxicology Testing, The Prescription Drug Abuse Epidemic, Substance Abuse Among Healthcare Professionals, Pain Management Drug Testing, Ethanol Biomarkers, Newly-emerging Drugs of Abuse, Synthetic Cannabinoids, Synthetic Cathenones, Immunoassay Methodology in Drugs-of-abuse Testing, Toxicology Testing in Alternative Specimen Matrices, Principles and Procedures in Postmortem Toxicology, and Pharmacogenetics and the Future of Toxicology Testing. Advances in toxicology testing are paving the way for major improvements in the way scientists evaluate health risks posed by toxic chemicals. Toxicity tests help scientists better understand how the human body carries out normal functions that are key to maintaining health. Therefore, this topic is important to the field of Laboratory Medicine.

PRACTICAL AND POSTMORTEM RECORD BOOK OF FORENSIC MEDICINE AND TOXICOLOGY

PRACTICAL AND POSTMORTEM RECORD BOOK OF FORENSIC MEDICINE AND TOXICOLOGY
Author: GAUTAM. BISWAS
Publsiher: Unknown
Total Pages: 135
Release: 2016
ISBN 10: 9789352501557
ISBN 13: 9352501551
Language: EN, FR, DE, ES & NL

PRACTICAL AND POSTMORTEM RECORD BOOK OF FORENSIC MEDICINE AND TOXICOLOGY Book Review:

Forensic Toxicology

Forensic Toxicology
Author: Robert H. Powers,Dorothy E. Dean
Publsiher: CRC Press
Total Pages: 273
Release: 2015-12-01
ISBN 10: 1466581956
ISBN 13: 9781466581951
Language: EN, FR, DE, ES & NL

Forensic Toxicology Book Review:

Designed for upper-level undergraduate and graduate-level courses, Forensic Toxicology: Mechanisms and Pathology introduces toxicology concepts from a forensic perspective. The book provides an understanding of the mechanistic basis of the action of drugs and toxins, addressing their physiologic and pathologic consequences on the affected organ sys

Propoxyphene in Postmortem Toxicology 1976 1978

Propoxyphene in Postmortem Toxicology 1976 1978
Author: BS. Finkle,YH. Caplan,JC. Garriott,Monforte, JR.,RF. Shaw,PK. Sonsalla
Publsiher: Unknown
Total Pages: 19
Release: 1981
ISBN 10: 1928374650XXX
ISBN 13: OCLC:1251677822
Language: EN, FR, DE, ES & NL

Propoxyphene in Postmortem Toxicology 1976 1978 Book Review:

A total of 1859 cases provides the basis for this study in which propoxyphene, and often its major metabolite, was demonstrated by toxicological analysis in the blood or tissues of the deceased at 27 medical examiner or coroner's offices across the United States and Canada. The study period includes the last five months of 1975 through December 1978. The cases describe a clearly defined adult population with a marked tendency toward hypochondria, chronic minor illness, and severe psychiatric problems. The high proportion of suicides (44.1% of the total cases and 54.0% of the drug-caused deaths) and multiple-drug toxicities (88.6%) suggests that the involvement of propoxyphene in many of these fatalities may be of less significance than the phenomenon of "polypharmacy" and self-medication without appropriate medical supervision. This evaluation of propoxyphene provides no evidence that propoxyphene is responsible for "street-drug" fatalities. Its appearance in postmortem toxicological examinations has been declining sharply since 1977, but it continues to be dangerous when used excessively, particularly in combination with alcohol and other central nervous system depressant drugs.

Postmortem Forensic Toxicology of Trazodone

Postmortem Forensic Toxicology of Trazodone
Author: BK. Logan,L. Raymon
Publsiher: Unknown
Total Pages: 7
Release: 2000
ISBN 10: 1928374650XXX
ISBN 13: OCLC:1251684116
Language: EN, FR, DE, ES & NL

Postmortem Forensic Toxicology of Trazodone Book Review:

Trazodone is a popular antidepressant medication that has been available for approximately 30 years. It has a reputation as a safe drug with relatively few reported fatalities attributed solely to it. We review the pharmacology and forensic toxicology of trazodone and report toxicology and cause and manner of death in a series of 37 deaths in which trazodone was detected.