Post Genomic Cardiology

Post Genomic Cardiology
Author: José Marín-García
Publsiher: Academic Press
Total Pages: 944
Release: 2014-05-09
ISBN 10: 0124046428
ISBN 13: 9780124046429
Language: EN, FR, DE, ES & NL

Post Genomic Cardiology Book Review:

In this second edition of Post-Genomic Cardiology, developing and new technologies such as translational genomics, next generation sequencing (NGS), bioinformatics, and systems biology in molecular cardiology are assessed in light of their therapeutic potential. As new methods of mutation screening emerge, both for the genome and for the “epigenome,” comprehensive understanding of the many mutations that underlie cardiovascular diseases and adverse drug reactions is within our reach. This book, written by respected cardiologist José Marín-García, features discussion on the Hap-Map: the largest international effort to date aiming to define the differences between our individual genomes. This unique reference further reviews and investigates genome sequences from our evolutionary relatives that could help us decipher the signals of genes, and offers a comprehensive and critical evaluation of regulatory elements from the complicated network of the background DNA. Offers updated discussion of cutting-edge molecular techniques including new genomic sequencing / NGS / Hap-Map / bioinformatics / systems biology approaches Analyzes mitochondria dynamics and their role in cardiac dysfunction, up-to-date analysis of cardio-protection, and cardio-metabolic syndrome Presents recent translational studies, gene therapy, transplantation of stem cells, and pharmacological treatments in CVDs

Aging and the Heart

Aging and the Heart
Author: José Marín-García
Publsiher: Springer Science & Business Media
Total Pages: 568
Release: 2007-12-07
ISBN 10: 9780387740720
ISBN 13: 0387740724
Language: EN, FR, DE, ES & NL

Aging and the Heart Book Review:

In this book, the genetic and molecular basis of cardiovascular aging is examined in detail and a comprehensive assessment given of the bioenergetics changes occurring in human and animal models of cardiac aging. Both current diagnostic and future therapeutic modalities are presented, giving this book a dual-pronged approach. Cardiac aging, like aging in general, is a complex process involving numerous cellular and molecular changes. This book sheds new light on the phenomenon.

American Book Publishing Record

American Book Publishing Record
Author: Anonim
Publsiher: Unknown
Total Pages: 329
Release: 2007
ISBN 10:
ISBN 13: UOM:39015066180442
Language: EN, FR, DE, ES & NL

American Book Publishing Record Book Review:

Heart Failure

Heart Failure
Author: José Marín-García
Publsiher: Springer Science & Business Media
Total Pages: 470
Release: 2010-06-23
ISBN 10: 1607611473
ISBN 13: 9781607611479
Language: EN, FR, DE, ES & NL

Heart Failure Book Review:

Heart Failure (HF) is the final and common pathway of all cardiovascular diseases. Heart Failure: Bench to Bedside helps address a significant need to develop new paradigms and to identify novel therapeutic targets for this pervasive disease. An authoritative contribution to the field, this book provides a detailed description of new findings and emerging methodologies, as well as a critical clinical evaluation of the complex HF syndrome and future therapies. Heart Failure: Bench to Bedside includes a primer on gene profiling and bioenergetics of the normal heart and a discussion of the molecular, genetic, biochemical and cellular techniques critical to understanding HF. Further chapters discuss cardiac remodeling, oxidative stress, and alterations in other organs and systems that are often associated with HF. This book thoughtfully evaluates current and forthcoming diagnostic techniques and therapies, pharmaceutical and pharmacogenomic-based individualized medicine, gene and cell-based therapies, and the search for new frontiers. Heart Failure: Bench to Bedside presents a clear view of up-to-date approaches to clinical diagnosis and treatment, as well as offering insightful critiques of original and creative scientific thoughts on post-genomic HF research.

Signaling in the Heart

Signaling in the Heart
Author: José Marín-García
Publsiher: Springer Science & Business Media
Total Pages: 507
Release: 2011-06-21
ISBN 10: 9781441994615
ISBN 13: 1441994610
Language: EN, FR, DE, ES & NL

Signaling in the Heart Book Review:

Signal transduction pathways are at the core of most biological processes and are critical regulators of heart physiology and pathophysiology. The heart is both a transmitter and dynamic receptor of a variety of intracellular and extracellular stimuli, playing a critical role of an integrator of diverse signaling mechanisms. Alterations in signaling pathways are contributing factors in the development and progression of a broad spectrum of diseases, ranging from dysrhythmias and atherosclerosis to hypertension and the metabolic syndrome. Targeting specific components of these signaling pathways has been shown to be effective in preclinical studies with significant therapeutic impact. This book brings together current knowledge in cardiovascular cell signal transduction mechanisms, advances in novel therapeutic approaches to improve cardiac function, and discussion of future directions. Presented from a post-genomic perspective, this exciting book introduces important new ideas in cardiovascular systems biology. It is an invaluable reference for cardiology researchers and practitioners.

Signaling in the Heart

Signaling in the Heart
Author: Anonim
Publsiher: Unknown
Total Pages: 528
Release: 2011-10-05
ISBN 10: 9781441994622
ISBN 13: 1441994629
Language: EN, FR, DE, ES & NL

Signaling in the Heart Book Review:

The EHRA Book of Pacemaker ICD and CRT Troubleshooting

The EHRA Book of Pacemaker  ICD  and CRT Troubleshooting
Author: Haran Burri,Carsten Israel,Jean-Claude Deharo
Publsiher: Oxford University Press, USA
Total Pages: 304
Release: 2015-03-29
ISBN 10: 0198727771
ISBN 13: 9780198727774
Language: EN, FR, DE, ES & NL

The EHRA Book of Pacemaker ICD and CRT Troubleshooting Book Review:

An essential companion for both the aspiring and practising electrophysiologist,The EHRA Book of Pacemaker, ICD and CRT Troubleshooting assists device specialists in tackling both common and unusual situations that that they may encounter during daily practice. Taking a case-based approach, it examines pacemakers, implantable cardioverter defibrillators and cardiac resynchronisation therapy. Much more than just a technical manual of device algorithms, the cases help readers to consolidate their technical knowledge, and improve their reasoning and observation skills so they are able to tackle device troubleshooting with confidence. The 70 cases are arranged in three sections by increasing levels of difficulty to walk readers through all the skills and knowledge they need in an easy to use and structured format. Each case contains a short clinical description and a device tracing followed by a multiple choice question. Answers are supplied with detailed annotations of the tracing and an in-depth discussion of the case, highlighting practical hints and tips as well as providing an overview of the technical function of devices. A useful summary of principal device features and functions is also included. The EHRA Book of Pacemaker, ICD and CRT Troubleshooting is the perfect companion for electrophysiologists, cardiology trainees and technical consultants working with device patients as well as for those studying for the EHRA accreditation exam in cardiac pacing.

Cardiovascular Genetics and Genomics

Cardiovascular Genetics and Genomics
Author: Dhavendra Kumar,Perry Elliott
Publsiher: Springer
Total Pages: 920
Release: 2018-01-17
ISBN 10: 3319661140
ISBN 13: 9783319661148
Language: EN, FR, DE, ES & NL

Cardiovascular Genetics and Genomics Book Review:

This title reflects the exponential growth in the knowledge and information on this subject and defines the extensive clinical translation of cardiovascular genetics and genomics in clinical practice. This concise, clinically oriented text is targeted at a broad range of clinicians who manage patients and families with a wide range of heterogeneous inherited cardiovascular conditions. Cardiovascular Genetics and Genomics: Principles and Clinical Practice includes a concise and clear account on selected topics written by a team of leading experts on clinical cardiovascular genetics. Each chapter include key information to assist the clinician and case histories have been incorporated to reflect contemporary practice in clinical cardiovascular genetics and genomics. Therefore this will be of key importance to all professionals working in the discipline, from clinicians and trainees in cardiology, cardiac surgery, electrophysiology, immunology through geneticists, nursing staff and those involved in precision medicine.

Environmental Epigenetics

Environmental Epigenetics
Author: L. Joseph Su,Tung-chin Chiang
Publsiher: Springer
Total Pages: 321
Release: 2015-05-18
ISBN 10: 1447166787
ISBN 13: 9781447166788
Language: EN, FR, DE, ES & NL

Environmental Epigenetics Book Review:

This book examines the toxicological and health implications of environmental epigenetics and provides knowledge through an interdisciplinary approach. Included in this volume are chapters outlining various environmental risk factors such as phthalates and dietary components, life states such as pregnancy and ageing, hormonal and metabolic considerations and specific disease risks such as cancer cardiovascular diseases and other non-communicable diseases. Environmental Epigenetics imparts integrative knowledge of the science of epigenetics and the issues raised in environmental epidemiology. This book is intended to serve both as a reference compendium on environmental epigenetics for scientists in academia, industry and laboratories and as a textbook for graduate level environmental health courses. Environmental Epigenetics imparts integrative knowledge of the science of epigenetics and the issues raised in environmental epidemiology. This book is intended to serve both as a reference compendium on environmental epigenetics for scientists in academia, industry and laboratories and as a textbook for graduate level environmental health courses.

Introductory Guide to Cardiac Catheterization

Introductory Guide to Cardiac Catheterization
Author: Arman T. Askari,Medhi H. Shishehbor,Adrian W. Messerli,Ronnier J. Aviles
Publsiher: Lippincott Williams & Wilkins
Total Pages: 224
Release: 2012-05-15
ISBN 10: 1451147864
ISBN 13: 9781451147865
Language: EN, FR, DE, ES & NL

Introductory Guide to Cardiac Catheterization Book Review:

Updated for its Second Edition, Introductory Guide to Cardiac Catheterization is an easy-to-follow "how-to" guide to diagnostic and therapeutic cardiac catheterization. This pocket-sized, concise manual presents practical pointers, tips, ACC/AHA guidelines, and highlighted clinical pearls and includes troubleshooting sections that provide solutions to frequently encountered problems. Numerous illustrations demonstrate the complex procedures now being performed via the catheter. This edition has a section on complications in each chapter, a new chapter on peripheral angiography, and a new question-and-answer review chapter. Other highlights include new safety precautions and updates on novel closure devices.

IOC Manual of Sports Cardiology

IOC Manual of Sports Cardiology
Author: Mathew G. Wilson,Jonathan A. Drezner,Sanjay Sharma
Publsiher: John Wiley & Sons
Total Pages: 528
Release: 2016-10-13
ISBN 10: 1119046874
ISBN 13: 9781119046875
Language: EN, FR, DE, ES & NL

IOC Manual of Sports Cardiology Book Review:

For the practicing sports medicine physician at the front line of sports cardiology, this comprehensive and authoritative resource provides a centralized source of information which addresses this important topic in an accessible manner. This book recognises the broad role sports physicians play, from liaison between athlete, family, specialist, and coaching staff based on the identification of pathological heart disease, to being first to respond when an athlete collapses. The chapters include basic science of disease and disorders, pathophysiology, diagnosis, the effect or role of exercise, and clinical management guidance. Provides a comprehensive and authoritative overview on all aspects of sports cardiology Addresses cardiac abnormalities confronting Olympic athletes, Paralympic athletes, as well as athletes competing on all other levels of competition Endorsed by the Medical Commission of the International Olympic Committee (IOC) Written and edited by global thought leaders in sports medicine

Handbook of Molecular and Cellular Methods in Biology and Medicine

Handbook of Molecular and Cellular Methods in Biology and Medicine
Author: Leland J. Cseke,Peter B. Kaufman,Gopi K. Podila,Chung-Jui Tsai
Publsiher: CRC Press
Total Pages: 600
Release: 2003-11-24
ISBN 10: 9781420041712
ISBN 13: 1420041711
Language: EN, FR, DE, ES & NL

Handbook of Molecular and Cellular Methods in Biology and Medicine Book Review:

Since the publication of the best-selling Handbook of Molecular and Cellular Methods in Biology and Medicine, the field of biology has experienced several milestones. Genome sequencing of higher eukaryotes has progressed at an unprecedented speed. Starting with baker's yeast (Saccharomyces cerevisiae), organisms sequenced now include human (Homo sa

Proteomic and Genomic Analysis of Cardiovascular Disease

Proteomic and Genomic Analysis of Cardiovascular Disease
Author: Jennifer E. Van Eyk,Michael J. Dunn
Publsiher: Wiley-Blackwell
Total Pages: 396
Release: 2003-04-10
ISBN 10:
ISBN 13: UOM:39015061093830
Language: EN, FR, DE, ES & NL

Proteomic and Genomic Analysis of Cardiovascular Disease Book Review:

This is the very first book to focus on this new approach that will eventually aid in developing new diagnostic markers and therapies for controlling and treating heart disease - the number-one killer in the industrialized world. Divided into two parts, the book describes not only the potentials, but also the limitations of these technologies. The editors, both well known within the scientific community, provide new insights into the biochemical and cellular mechanisms of cardiovascular disease, as well as covering the transition into clinical applications. In so doing, they highlight the various strategies and technical aspects so as to assist the growing number of researchers intending to utilize these approaches. The result is an excellent way of educating and informing graduate students, post-doctoral fellows as well as researchers in academia and industry about the latest developments in this area.

Genomic Medicine

Genomic Medicine
Author: Dhavendra Kumar,Charis Eng
Publsiher: Oxford University Press (UK)
Total Pages: 814
Release: 2014
ISBN 10: 019989602X
ISBN 13: 9780199896028
Language: EN, FR, DE, ES & NL

Genomic Medicine Book Review:

Preceded by Genomics and clinical medicine / edited by Dhavendra Kumar. [First edition]. 2008.

Journal of molecular and cell cardiology

Journal of molecular and cell cardiology
Author: Anonim
Publsiher: Unknown
Total Pages: 329
Release: 1990
ISBN 10:
ISBN 13: UCAL:B4360430
Language: EN, FR, DE, ES & NL

Journal of molecular and cell cardiology Book Review:

P5 Medicine and Justice

P5 Medicine and Justice
Author: Santo Davide Ferrara
Publsiher: Springer
Total Pages: 635
Release: 2018-03-27
ISBN 10: 3319670921
ISBN 13: 9783319670928
Language: EN, FR, DE, ES & NL

P5 Medicine and Justice Book Review:

This book describes the state of the art and future prospects of the most important bio-medicolegal subdisciplines in the post-genomic framework of personalized medicine. Focusing on the three main themes Innovation, Unitariness and Evidence, the book addresses a wide range of topics, including: Bio-Medicolegal and Criminological Sciences, Forensic Pathology and Anthropology, Clinical and Forensic Medicine in Living Persons (from Interpersonal Violence to Personal Injury and Damage, Malpractice, Personal Identification and Age Estimation), Forensic Genetics and Genomics, and Toxicology and Imaging. The unitariness of the “Bio-Medicolegal Sciences”, historically founded on the accuracy and rigor of the methods of ascertainment and criteria of evaluation, should be re-established on the basis of molecular evidence, and used to promote Personalized Justice. Taken together, the book’s conclusions and future perspectives outline a vision of transdisciplinary innovation and future evidence in the framework of personalized justice.

Promoting Cardiovascular Health in the Developing World

Promoting Cardiovascular Health in the Developing World
Author: Institute of Medicine,Board on Global Health,Committee on Preventing the Global Epidemic of Cardiovascular Disease: Meeting the Challenges in Developing Countries
Publsiher: National Academies Press
Total Pages: 482
Release: 2010-07-29
ISBN 10: 0309147743
ISBN 13: 9780309147743
Language: EN, FR, DE, ES & NL

Promoting Cardiovascular Health in the Developing World Book Review:

Cardiovascular disease (CVD), once thought to be confined primarily to industrialized nations, has emerged as a major health threat in developing countries. Cardiovascular disease now accounts for nearly 30 percent of deaths in low and middle income countries each year, and is accompanied by significant economic repercussions. Yet most governments, global health institutions, and development agencies have largely overlooked CVD as they have invested in health in developing countries. Recognizing the gap between the compelling evidence of the global CVD burden and the investment needed to prevent and control CVD, the National Heart, Lung, and Blood Institute (NHLBI) turned to the IOM for advice on how to catalyze change. In this report, the IOM recommends that the NHLBI, development agencies, nongovernmental organizations, and governments work toward two essential goals: creating environments that promote heart healthy lifestyle choices and help reduce the risk of chronic diseases, and building public health infrastructure and health systems with the capacity to implement programs that will effectively detect and reduce risk and manage CVD. To meet these goals, the IOM recommends several steps, including improving cooperation and collaboration; implementing effective and feasible strategies; and informing efforts through research and health surveillance. Without better efforts to promote cardiovascular health, global health as a whole will be undermined.

Endocrinology of the Heart in Health and Disease

Endocrinology of the Heart in Health and Disease
Author: Jonathan C. Schisler,Charles H Lang,Monte Willis
Publsiher: Academic Press
Total Pages: 378
Release: 2016-10-19
ISBN 10: 0128031123
ISBN 13: 9780128031124
Language: EN, FR, DE, ES & NL

Endocrinology of the Heart in Health and Disease Book Review:

Endocrinology of the Heart in Health and Disease: Integrated, Cellular, and Molecular Endocrinology of the Heart covers the traditional concepts of cardio-endocrinology, the role of the various hormone systems, both in health and disease, therapeutic implications, and other recent advances in the various fields represented. The book explores how cardiac hormones are changed in various cardiac pathologies and the recent success that has been uncovered in their therapeutic use. Additional focus is placed on how the heart responds both physiologically and pathophysiologically to a plethora of circulating hormones, reinforcing the importance of the heart as a target of numerous endocrine systems, such as the brain, renal, and adipose. Significant advances have come from basic, clinical, and translational research from a multiplicity of investigators with diverse backgrounds. The book features over 200 photomicrographs, diagrams of molecular relationships, and tables that complement and support the text. It is aimed at a wide audience, including graduate students and post-doctoral fellows in a wide array of biomedical departments and PhD programs (e.g. Pathology, Physiology, Genetics, Pharmacology, Molecular Biology, and Cell Biology) related to the endocrine and cardiovascular sciences curricula, as well as medical residents in pathology, laboratory medicine, internal medicine, and cardiology. Develops the concept of the heart as both an endocrine organ and an endocrine target, exploring the endocrine function of the heart in both health and disease Explains how the levels of several cardiac hormones are changed in various cardiac pathologies and how some hormones can be used therapeutically Offers a single resource on cardio-endocrine disease which collates and curates the wide range of advances being made in the areas of molecular biology, biochemistry, physiology, and pathology

I Am Love

I Am Love
Author: Susan Verde
Publsiher: Abrams
Total Pages: 32
Release: 2019-09-17
ISBN 10: 1683355687
ISBN 13: 9781683355687
Language: EN, FR, DE, ES & NL

I Am Love Book Review:

A celebration of love and connection for young readers Susan Verde and Peter H. Reynolds continue their collaboration with the fourth book in their bestselling wellness series. A celebration of love in all its forms, I Am Love asks readers to look inward when they feel afraid. Love allows us to act with compassion and kindness, to live with gratitude, and to take care of ourselves by practicing self-love.

Cardiovascular Pharmacogenetics

Cardiovascular Pharmacogenetics
Author: Martin R. Wilkins
Publsiher: Springer Science & Business Media
Total Pages: 407
Release: 2003-12-02
ISBN 10: 9783540402046
ISBN 13: 3540402047
Language: EN, FR, DE, ES & NL

Cardiovascular Pharmacogenetics Book Review:

The Human Genome Project was sold to the general public largely on the basis that a complete picture of the structure of human DNA would lead to new and better medicines. These medicines would be better because they would be tailored to individual patients, maximising the chances of a therapeutic response and mi nimising the risks of an adverse event. Taking the idea further, pundits have pre dicted that the time will come when we could carry our DNA on a card which could be read rapidly and enable the physician to choose the best drug. This is the future. This is pharmacogenetics. When the draft human DNA sequence was announced and scientists were as ked how this would help drug development, the example most frequently given was the debrisoquine model - where poor metabolisers of this hypotensive agent are exposed to higher plasma levels from a standard dose and at risk of collapse from excessive hypotension. This observation was made over 20 years ago and predated designs to sequence the human genome. Nonetheless, it raised aware ness of variation in drug metabolism and was correctly assigned to genetic poly morphisms affecting CYP2D6. Together with the discovery of pseudocholinestera se deficiency, it marked the birth of pharmacogenetics. The debrisoquine example is an interesting one and worthy of further analysis.