Polymer Protein Conjugates

Polymer Protein Conjugates
Author: Gianfranco Pasut,Samuel Zalipsky
Publsiher: Elsevier
Total Pages: 512
Release: 2019-10-30
ISBN 10: 0444640827
ISBN 13: 9780444640826
Language: EN, FR, DE, ES & NL

Polymer Protein Conjugates Book Review:

Polymer–Protein Conjugates: From Pegylation and Beyond helps researchers by offering a unique reference and guide into this fascinating area. Sections cover the challenges surrounding the homogeneity of conjugates, their purity and polymer toxicity on long-term use, and how to deal with the risk of immunogenicity. These discussions help researchers design new projects by taking into account the latest innovations for safe and site selective polymer conjugation to proteins. PEG has been the gold standard and likely will play this role for many years, but alternatives are coming into the market, some of which have already been launched. After five decades of improvements, the ideas in this book are entering into a new era of innovation because of the advances in genetic engineering, biochemistry and a better understanding of the results from clinical use of PEG conjugates in humans. Provides an overview on the state-of-the-art of protein polymer conjugation Presents both the pros and cons of polymer-protein conjugates from the point-of-view of their clinical outcomes Outlines advantages and potential risks of present technology based on PEG Offers new alternatives for PEG and new approaches for on site-selective protein modification Identifies future direction of research in this field

Polymer Protein Conjugates

Polymer Protein Conjugates
Author: Gianfranco Pasut,Samuel Zalipsky
Publsiher: Unknown
Total Pages: 312
Release: 2019-11
ISBN 10: 9780444640819
ISBN 13: 0444640819
Language: EN, FR, DE, ES & NL

Polymer Protein Conjugates Book Review:

Polymer-Protein Conjugates: From Pegylation and Beyond helps researchers by offering a unique reference and guide into this fascinating area. Sections cover the challenges surrounding the homogeneity of conjugates, their purity and polymer toxicity on long-term use, and how to deal with the risk of immunogenicity. These discussions help researchers design new projects by taking into account the latest innovations for safe and site selective polymer conjugation to proteins. PEG has been the gold standard and likely will play this role for many years, but alternatives are coming into the market, some of which have already been launched. After five decades of improvements, the ideas in this book are entering into a new era of innovation because of the advances in genetic engineering, biochemistry and a better understanding of the results from clinical use of PEG conjugates in humans. Provides an overview on the state-of-the-art of protein polymer conjugation Presents both the pros and cons of polymer-protein conjugates from the point-of-view of their clinical outcomes Outlines advantages and potential risks of present technology based on PEG Offers new alternatives for PEG and new approaches for on site-selective protein modification Identifies future direction of research in this field

PEGylated Protein Drugs Basic Science and Clinical Applications

PEGylated Protein Drugs  Basic Science and Clinical Applications
Author: Francesco M. Veronese
Publsiher: Springer Science & Business Media
Total Pages: 290
Release: 2009-12-30
ISBN 10: 3764386797
ISBN 13: 9783764386795
Language: EN, FR, DE, ES & NL

PEGylated Protein Drugs Basic Science and Clinical Applications Book Review:

PEGylation technology and key applications are introduced by this topical volume. Basic physical and chemical properties of PEG as basis for altering/improving in vivo behaviour of PEG-conjugates such as increased stability, improved PK/PD, and decreased immunogenicity, are discussed. Furthermore, chemical and enzymatic strategies for the coupling and the conjugate characterization are reported. Following chapters describe approved and marketed PEG-proteins and PEG-oligonucleotides as well as conjugates in various stages of clinical development.

Protein based Engineered Nanostructures

Protein based Engineered Nanostructures
Author: Aitziber L. Cortajarena,Tijana Z. Grove
Publsiher: Springer
Total Pages: 286
Release: 2016-09-27
ISBN 10: 3319391968
ISBN 13: 9783319391960
Language: EN, FR, DE, ES & NL

Protein based Engineered Nanostructures Book Review:

This book is devoted to the engineering of protein-based nanostructures and nanomaterials. One key challenge in nanobiotechnology is to be able to exploit the natural repertoire of protein structures and functions to build materials with defined properties at the nanoscale using “bottom-up” strategies. This book addresses in an integrated manner all the critical aspects that need to be understood and considered to design the next generation of nano-bio assemblies. The book covers first the fundamentals of the design and features of the protein building blocks and their self-assembly illustrating some of the most relevant examples of nanostructural design. Finally, the book contains a section dedicated to demonstrated applications of these novel bioinspired nanostructures in different fields from hybrid nanomaterials to regenerative medicine. This book provides a comprehensive updated review of this rapidly evolving field.

Bioconjugate Techniques

Bioconjugate Techniques
Author: Greg T. Hermanson
Publsiher: Academic Press
Total Pages: 1200
Release: 2013-07-25
ISBN 10: 0123822408
ISBN 13: 9780123822406
Language: EN, FR, DE, ES & NL

Bioconjugate Techniques Book Review:

Bioconjugate Techniques, 3rd Edition, is the essential guide to the modification and cross linking of biomolecules for use in research, diagnostics, and therapeutics. It provides highly detailed information on the chemistry, reagent systems, and practical applications for creating labeled or conjugate molecules. It also describes dozens of reactions, with details on hundreds of commercially available reagents and the use of these reagents for modifying or crosslinking peptides and proteins, sugars and polysaccharides, nucleic acids and oligonucleotides, lipids, and synthetic polymers. Offers a one-stop source for proven methods and protocols for synthesizing bioconjugates in the lab Provides step-by-step presentation makes the book an ideal source for researchers who are less familiar with the synthesis of bioconjugates Features full color illustrations Includes a more extensive introduction into the vast field of bioconjugation and one of the most thorough overviews of immobilization chemistry ever presented

Self Assembly

Self Assembly
Author: Ramanathan Nagarajan
Publsiher: John Wiley & Sons
Total Pages: 368
Release: 2019-01-07
ISBN 10: 1119001366
ISBN 13: 9781119001362
Language: EN, FR, DE, ES & NL

Self Assembly Book Review:

An introduction to the state-of-the-art of the diverse self-assembly systems Self-Assembly: From Surfactants to Nanoparticles provides an effective entry for new researchers into this exciting field while also giving the state of the art assessment of the diverse self-assembling systems for those already engaged in this research. Over the last twenty years, self-assembly has emerged as a distinct science/technology field, going well beyond the classical surfactant and block copolymer molecules, and encompassing much larger and complex molecular, biomolecular and nanoparticle systems. Within its ten chapters, each contributed by pioneers of the respective research topics, the book: Discusses the fundamental physical chemical principles that govern the formation and properties of self-assembled systems Describes important experimental techniques to characterize the properties of self-assembled systems, particularly the nature of molecular organization and structure at the nano, meso or micro scales. Provides the first exhaustive accounting of self-assembly derived from various kinds of biomolecules including peptides, DNA and proteins. Outlines methods of synthesis and functionalization of self-assembled nanoparticles and the further self-assembly of the nanoparticles into one, two or three dimensional materials. Explores numerous potential applications of self-assembled structures including nanomedicine applications of drug delivery, imaging, molecular diagnostics and theranostics, and design of materials to specification such as smart responsive materials and self-healing materials. Highlights the unifying as well as contrasting features of self-assembly, as we move from surfactant molecules to nanoparticles. Written for students and academic and industrial scientists and engineers, by pioneers of the research field, Self-Assembly: From Surfactants to Nanoparticles is a comprehensive resource on diverse self-assembly systems, that is simultaneously introductory as well as the state of the art.

Polymer Therapeutics I

Polymer Therapeutics I
Author: Ronit Satchi-Fainaro,Ruth Duncan
Publsiher: Springer Science & Business Media
Total Pages: 204
Release: 2006-02-10
ISBN 10: 9783540292104
ISBN 13: 3540292101
Language: EN, FR, DE, ES & NL

Polymer Therapeutics I Book Review:

Polymer Modification

Polymer Modification
Author: Graham G. Swift,Charles E. Carraher Jr.,Chris Bowman
Publsiher: Springer Science & Business Media
Total Pages: 212
Release: 2013-06-29
ISBN 10: 1489914773
ISBN 13: 9781489914774
Language: EN, FR, DE, ES & NL

Polymer Modification Book Review:

Proceedings of an ACS-PMSE Division Symposium held in Orlando, Florida, August 21-25, 1996

Smart Polymer Catalysts and Tunable Catalysis

Smart Polymer Catalysts and Tunable Catalysis
Author: Songjun Li,Peter A. Lieberzeit,Sergey A. Piletsky,Anthony P.F. Turner
Publsiher: Elsevier
Total Pages: 300
Release: 2019-09-10
ISBN 10: 0128118725
ISBN 13: 9780128118726
Language: EN, FR, DE, ES & NL

Smart Polymer Catalysts and Tunable Catalysis Book Review:

Smart Polymer Catalysts and Tunable Catalysis describes the latest advances in smart polymer catalysts and tunable catalysis. This book will serve as an ideal reference for scientists, students and researchers working in the fields of catalysis, chemical engineering, chemistry, materials science, biotechnology and nanotechnology. Users will find this to be a distinct, systematic and comprehensive body of knowledge on the field with its compilation of essential knowledge and discussions of extensive potential in both social and commercial impacts. Provides a single-source summary of the emerging frontiers in scientific research in smart polymer catalysts and tunable catalysis Includes very well-organized chapters that are illustrated with over 130 illustrations and figures Written by scientists from prestigious universities and industries across the world Edited by veteran researchers in the field of smart polymers and catalysis

Reactive Polymers

Reactive Polymers
Author: Karl-F. Arndt,Dirk Kuckling,Manfred Stamm,Brigitte Voit,Thomas Wolff
Publsiher: Wiley-VCH
Total Pages: 486
Release: 2001-06-15
ISBN 10:
ISBN 13: STANFORD:36105110481517
Language: EN, FR, DE, ES & NL

Reactive Polymers Book Review:

This volume of Macromolecular Symposia contains papers presented at the 1st International Symposium on "Reactive Polymers in Inhomogeneous Systems, in Melts and at Interfaces" held in Dresden Germany in July 2000. It includes 42 contributions from renowned scientists dealing with topics of current interest in the field of synthesis, characterization and application of reactive and functional polymers. The papers add significantly to the current understanding of the role of reactive polymers in phenomena such as adhesion, colloidal stability, corrosion resistance and biocompatibility - comprehension which is vital for improving the polymer technologies available today and for the development of new applications.

Polymer Therapeutics II

Polymer Therapeutics II
Author: Ronit Satchi-Fainaro,Ruth Duncan
Publsiher: Springer Science & Business Media
Total Pages: 230
Release: 2006-01-12
ISBN 10: 9783540292111
ISBN 13: 354029211X
Language: EN, FR, DE, ES & NL

Polymer Therapeutics II Book Review:

With contributions by numerous experts

Natural Polymers for Drug Delivery

Natural Polymers for Drug Delivery
Author: Harsha Kharkwal,Srinivas Janaswamy
Publsiher: CABI
Total Pages: 216
Release: 2016-12-07
ISBN 10: 1780644477
ISBN 13: 9781780644479
Language: EN, FR, DE, ES & NL

Natural Polymers for Drug Delivery Book Review:

Natural polymers have been utilized extensively in food, pharmaceuticals, cosmetics, textiles, oil drilling and paint industries. Their non-toxic and inexpensive attributes readily enhance their commercial acceptability and make them potent agents in lieu of synthetic polymers. This book explores the opportunistic utility of natural polymers in developing effective drug delivery systems and provides a comprehensive and up-to-date analysis of their source, chemical structure and mechanism of action. Covering novel polymers for drug delivery - in particular extracts from plants, microorganisms and proteins, as well as water soluble and water insoluble biodegradable polymers - it presents an encyclopaedic overview of natural polymers'. Natural Polymers for Drug Delivery is an invaluable resource for researchers, students and industrial scientists in the fields of biochemistry, chemistry, pharmacology and food science.

Bioconjugation Protocols

Bioconjugation Protocols
Author: Sonny S. Mark
Publsiher: Humana Press
Total Pages: 605
Release: 2016-08-23
ISBN 10: 9781493960965
ISBN 13: 1493960962
Language: EN, FR, DE, ES & NL

Bioconjugation Protocols Book Review:

Contemporary approaches to the synthesis of chemically modified biomacromolecules (proteins, nucleic acids, lipids, and carbohydrates) not only require efficient means to control conjugation and the specific site of attachment of the conjugated moiety but also the effective use of recent developments in the fields of pharmaceutical chemistry, biomolecular/polymer engineering, and nanobiotechnology. In this second edition of Bioconjugation Protocols: Strategies and Methods, expert researchers update the classic methods and introduce valuable new approaches that go beyond basic conjugation techniques to include elements from advanced organic synthesis, molecular biology, surface biotechnology, materials science, and nanobioscience/engineering. These readily reproducible methods cover the preparation of biomolecular conjugates using a variety of labeling techniques and semisynthetic approaches. Additional chapters address the biofunctionalization of surface structures, including organic/inorganic thin films, as well as various types of nanostructures (magnetic nanoparticles, quantum dots, carbon nanotubes, and silicon nanowire devices). All the protocols follow the successful Methods in Molecular BiologyTM series format, each one offering step-by-step laboratory instructions, an introduction outlining the principle behind the technique, lists of the necessary equipment and reagents, and tips on troubleshooting and avoiding known pitfalls. Cutting-edge and highly practical, Bioconjugation Protocols: Strategies and Methods, Second Edition offers both novice and experienced researchers access to the broad array of techniques needed to carry out the semisynthesis of functional biomolecular reagents and/or the biofunctionalization of surfaces and structures of unique interest for a wide variety of applications, ranging from novel biomedical diagnostics to powerful new therapeutics to advanced biomaterials.

Compendium of Polymer Terminology and Nomenclature

Compendium of Polymer Terminology and Nomenclature
Author: International Union of Pure and Applied Chemistry. Commission on Macromolecular Nomenclature,Richard G. Jones
Publsiher: Royal Society of Chemistry
Total Pages: 443
Release: 2009-01
ISBN 10: 0854044914
ISBN 13: 9780854044917
Language: EN, FR, DE, ES & NL

Compendium of Polymer Terminology and Nomenclature Book Review:

Rev. and enl. ed. of: Compendium of macromolecular nomenclature. 1991.

Polymer Biomaterials in Solution As Interfaces And As Solids

Polymer Biomaterials in Solution  As Interfaces And As Solids
Author: Stuart L. Cooper,C. H. Bamford,Teiji Tsuruta,T. Tsuruta
Publsiher: VSP
Total Pages: 1
Release: 1995-03
ISBN 10: 9789067641807
ISBN 13: 9067641804
Language: EN, FR, DE, ES & NL

Polymer Biomaterials in Solution As Interfaces And As Solids Book Review:

The articles collected in this publication have previously been published in eight special issues of the Journal of Biomaterials Science, Polymer Edition, in honour of Dr. Allan S. Hoffman, who is known as a pioneer, a leader and a mentor in the field of biomaterials. The papers from renowned scientists from all parts of the world, representing the state-of-the-art in polymeric biomaterials today, have been rearranged into a logical order of sections, each having a distinct focus. The topics covered are: Surface Modification, Characterization and Properties; Protein Adsorption; Blood Interactions; Cell Interactions; Immobilized Cell Receptor Ligands and Immobilized Cells; Immobilized Biomolecules and Synthetic Derivatives of Biomolecules; New Polymers and Applications; Biodegradable Polymers and Drug Delivery; Water-Soluble Biomolecules, Sunthetic Polymers, and their Conjugates; Hydrogels.

Supramolecular Protein Chemistry

Supramolecular Protein Chemistry
Author: Peter B. Crowley
Publsiher: Royal Society of Chemistry
Total Pages: 329
Release: 2020-12-14
ISBN 10: 1788017544
ISBN 13: 9781788017541
Language: EN, FR, DE, ES & NL

Supramolecular Protein Chemistry Book Review:

Assembly, Architecture and Application

Biosynthetic Polymers for Medical Applications

Biosynthetic Polymers for Medical Applications
Author: Laura Poole-Warren,Penny Martens,Rylie Green
Publsiher: Elsevier
Total Pages: 358
Release: 2015-11-23
ISBN 10: 1782421130
ISBN 13: 9781782421139
Language: EN, FR, DE, ES & NL

Biosynthetic Polymers for Medical Applications Book Review:

Biosynthetic Polymers for Medical Applications provides the latest information on biopolymers, the polymers that have been produced from living organisms and are biodegradable in nature. These advanced materials are becoming increasingly important for medical applications due to their favorable properties, such as degradability and biocompatibility. This important book provides readers with a thorough review of the fundamentals of biosynthetic polymers and their applications. Part One covers the fundamentals of biosynthetic polymers for medical applications, while Part Two explores biosynthetic polymer coatings and surface modification. Subsequent sections discuss biosynthetic polymers for tissue engineering applications and how to conduct polymers for medical applications. Comprehensively covers all major medical applications of biosynthetic polymers Provides an overview of non-degradable and biodegradable biosynthetic polymers and their medical uses Presents a specific focus on coatings and surface modifications, biosynthetic hydrogels, particulate systems for gene and drug delivery, and conjugated conducting polymers

Natural Polymers

Natural Polymers
Author: Ololade Olatunji
Publsiher: Springer
Total Pages: 370
Release: 2015-12-24
ISBN 10: 3319264141
ISBN 13: 9783319264141
Language: EN, FR, DE, ES & NL

Natural Polymers Book Review:

This book introduces the most recent innovations in natural polymer applications in the food, construction, electronics, biomedical, pharmaceutical, and engineering industries. The authors provide perspectives from their respective range of industries covering classification, extraction, modification, and application of natural polymers from various sources in nature. They discuss the techniques used in analysis of natural polymers in various systems incorporating natural polymers as well as their intrinsic properties.

Drug Delivery

Drug Delivery
Author: Binghe Wang,Longqin Hu,Teruna J. Siahaan
Publsiher: John Wiley & Sons
Total Pages: 720
Release: 2016-03-09
ISBN 10: 1118833309
ISBN 13: 9781118833308
Language: EN, FR, DE, ES & NL

Drug Delivery Book Review:

Following its successful predecessor, this book covers the fundamentals, delivery routes and vehicles, and practical applications of drug delivery. In the 2nd edition, almost all chapters from the previous are retained and updated and several new chapters added to make a more complete resource and reference. • Helps readers understand progress in drug delivery research and applications • Updates and expands coverage to reflect advances in materials for delivery vehicles, drug delivery approaches, and therapeutics • Covers recent developments including transdermal and mucosal delivery, lymphatic system delivery, theranostics • Adds new chapters on nanoparticles, controlled drug release systems, theranostics, protein and peptide drugs, and biologics delivery

Cationic Polymers in Regenerative Medicine

Cationic Polymers in Regenerative Medicine
Author: Sangram Keshari Samal,Peter Dubruel
Publsiher: Royal Society of Chemistry
Total Pages: 612
Release: 2014-11-14
ISBN 10: 1782620109
ISBN 13: 9781782620105
Language: EN, FR, DE, ES & NL

Cationic Polymers in Regenerative Medicine Book Review:

The unique physico-chemical properties of cationic polymers and their ability to be easily modified make them attractive for many biological applications. As a result there is a vast amount of research focussed on designing novel natural or synthetic cationic polymers with specific biological functionality. Cationic Polymers in Regenerative Medicine brings together the expertise of leading experts in the field to provide a comprehensive overview of the recent advances in cationic polymer synthesis, modification and the design of biomaterials with different structures for therapeutic applications. Chapters cover recent developments in novel cationic polymer based systems including poly(L-lysine), Poly(N,N-dimethylaminoethyl methacrylate) and cationic triazine dendrimers as well as cationic polymer-coated micro- and nanoparticles and cationic cellulose and chitin nanocrystals. Applications discussed in the book include drug and gene delivery, therapeutics in thrombosis and inflammation as well as gene therapy. Suitable both for an educational perspective for those new to the field and those already active in the field, the book appeals to postgraduates and researchers. The broad aspects of the topics covered are suitable for polymer chemists interested in the fundamentals of the materials systems as well as pharmaceutical chemists, bioengineering and medical professionals interested in their applications.