Planning and Designing Research Animal Facilities

Research institutions have or are planning to build, expand and renovate animal research facilities to keep up with the demands of biomedical research caused in part by growth in the use of genetically altered rodents and the upsurge of research in infectious diseases. Properly designed facilities greatly facilitate effective management and high-quality day-to-day animal care that is required to optimally support animal research and testing. There are multiple solutions to address the myriad of factors that influence the design and construction of animal research facilities. There is no “best design applicable for all facilities and arguably not even a single “best design for a given facility. For this reason, Planning and Designing Research Animal Facilities is not intended to be a “how to book. The goal is to cover the basic programmatic requirements of animal research facilities, provide ideas for meeting those requirements while, hopefully, stimulating the creative process in which designers in consultation with those who work in animal research facilities generate even better ideas. That is how progress has been made and will continue to be made. Facilitates communication between the parties involved in planning and designing animal facilities by providing contemporary information, and stimulating creativity that will help lead to wise decisions and advance the knowledge base for planning, design and constructing animal research facilities

Research institutions have or are planning to build, expand and renovate animal research facilities to keep up with demands of biomedical research caused in part by growth in the use of genetically altered rodents and the upsurge of research in infectious diseases. Properly designed facilities greatly facilitate effective management and high quality day-to-day animal care that is required to optimally support animal research and testing. There are multiple solutions to address the myriad of factors that influence the design and construction of research animal facilities. There is no “best” design applicable for all facilities and arguably not even a single “best” design for a given facility. For this reason, this is not intended to be a “how to” book. The goal is to cover the basic programmatic requirements of animal research facilities, provide ideas for meeting those requirements while, hopefully, stimulating the creative process in which designers in consultation with those who work in research animal facilities generate even better ideas. That is how progress has been made and will continue to be made. * Focuses primarily on biomedical research and development facilities * Facilitates communication between the various disciplines involved in planning and designing animal facilities by providing contemporary information, and stimulating creativity that will help lead to wise decisions and advance the knowledge base for planning, design and constructing research animal facilities

AAP Prose Award Finalist 2018/19 Management of Animal Care and Use Programs in Research, Education, and Testing, Second Edition is the extensively expanded revision of the popular Management of Laboratory Animal Care and Use Programs book published earlier this century. Following in the footsteps of the first edition, this revision serves as a first line management resource, providing for strong advocacy for advancing quality animal welfare and science worldwide, and continues as a valuable seminal reference for those engaged in all types of programs involving animal care and use. The new edition has more than doubled the number of chapters in the original volume to present a more comprehensive overview of the current breadth and depth of the field with applicability to an international audience. Readers are provided with the latest information and resource and reference material from authors who are noted experts in their field. The book: - Emphasizes the importance of developing a collaborative culture of care within an animal care and use program and provides information about how behavioral management through animal training can play an integral role in a veterinary health program - Provides a new section on Environment and Housing, containing chapters that focus on management considerations of housing and enrichment delineated by species - Expands coverage of regulatory oversight and compliance, assessment, and assurance issues and processes, including a greater discussion of globalization and harmonizing cultural and regulatory issues - Includes more in-depth treatment throughout the book of critical topics in program management, physical plant, animal health, and husbandry. Biomedical research using animals requires administrators and managers who are knowledgeable and highly skilled. They must adapt to the complexity of rapidly-changing technologies, balance research goals with a thorough understanding of regulatory requirements and guidelines, and know how to work with a multi-generational, multi-cultural workforce. This book is the ideal resource for these professionals. It also serves as an indispensable resource text for certification exams and credentialing boards for a multitude of professional societies Co-publishers on the second edition are: ACLAM (American College of Laboratory Animal Medicine); ECLAM (European College of Laboratory Animal Medicine); IACLAM (International Colleges of Laboratory Animal Medicine); JCLAM (Japanese College of Laboratory Animal Medicine); KCLAM (Korean College of Laboratory Animal Medicine); CALAS (Canadian Association of Laboratory Animal Medicine); LAMA (Laboratory Animal Management Association); and IAT (Institute of Animal Technology).

A respected resource for decades, the Guide for the Care and Use of Laboratory Animals has been revised by a committee of experts, based on input from scientists and the public. The Guide incorporates recent research on commonly used species, including farm animals, and includes extensive references. It is organized around major components of animal use: Institutional policies and responsibilities. The committee discusses areas that require policy attention: the role and function of the Institutional Animal Care and Use Committee, protocols for animal care and use, occupational health and safety, personnel qualifications, and other areas. Animal environment, husbandry, and management. The committee offers guidelines on how to design and run a management program, addressing environment, nutrition, sanitation, behavioral and social issues, genetics, nomenclature, and more. Veterinary care. The committee discusses animal procurement and transportation, disease and preventive medicine, and surgery. The Guide addresses pain recognition and relief and issues surrounding euthanasia. Physical plant. The committee identifies design and construction issues, providing guidelines for animal-room doors, drainage, noise control, surgery, and other areas. The Guide for the Care and Use of Laboratory Animals provides a framework for the judgments required in the management of animal facilities--a resource of proven value, now updated and expanded. This revision will be important to researchers, animal care technicians, facilities managers, administrators at research institutions, policymakers involved in research issues, and animal welfare advocates.

Much has been written about the care of research animals. Yet little guidance has appeared on protecting the health and safety of the people who care for or use these animals. This book, an implementation handbook and companion to Guide For the Care and Use of Laboratory Animals, identifies principles for building a program and discusses the accountability of institutional leaders, managers, and employees for a program's success. It provides a detailed description of risks-- physical and chemical hazards, allergens and zoonoses, and hazards from experiments--which will serve as a continuing reference for the laboratory. The book offers specific recommendations for controlling risk through administrative procedures, facility design, engineering controls, and periodic evaluations. The volume focuses on the worker, with detailed discussions of work practices, the use of personal protective gear, and the development of an emergency response plan. This handbook will be invaluable to administrators, researchers, and employees in any animal research facility. It will also be of interest to personnel in zoos, animal shelters, and veterinary facilities.

Laboratory animal testing provides most of our current knowledge of human physiology, microbiology, immunology, pharmacology, and pathology. From studies of genetics in fruit flies to studies of cellular processes in genetically modified mice to recent dramatic developments in genetics, translational research, and personalized medicines, biomedical

Laboratory facilities are complex, technically sophisticated, and mechanically intensive structures that are expensive to build and to maintain. Hundreds of decisions must be made before and during new construction or renovation that will determine how successfully the facility will function when completed and how successfully it can be maintained once put into service. This book provides guidance on effective approaches for building laboratory facilities in the chemical and biochemical sciences. It contains both basic and laboratory-specific information addressed to the user community-the scientists and administrators who contract with design and construction experts. The book will also be important to the design and construction communities-the architects, laboratory designers, and engineers who will design the facility and the construction personnel who will build it-to help them communicate with the scientific community for whom they build laboratory facilities.

DESIGN and PLANNING of Research and Clinical LABORATORYFACILITIES In this primer/professional reference, Leonard Mayer demystifiesone of the most complex architectural specialties. An architectwith more than thirty-three years' experience as a master plannerand programmer of laboratories and clinical facilities, Mr. Mayeroffers a comprehensive overview of the fundamental issues relatedto laboratory planning and design. He also provides designers witha clear and rational framework through which to approach thishighly challenging and rewarding design specialty. A superblearning tool for students and professionals just getting startedin lab design and a valuable one-volume reference for theexperienced professional, Design and Planning of Research andClinical Laboratory Facilities features: * Step-by-step guidance through the complex maze of codes,specifications, standards, and official guidelines, relating to theplanning, design, and construction processes * New and updated design criteria based on the most recent laws andregulations * Master plans, facility programs, functional programs andrequirements programs for a wide variety of scientific and medicaldisciplines and support facilities * Comprehensive lists of relevant codes, regulations, standards,guidelines, and important architectural, structural, mechanical,electrical, and plumbing criteria Research and clinical laboratory facilities are, perhaps, the mostcomplex structures to plan and design. Intimidated by a vast andseemingly impenetrable body of codes, regulations, and designcriteria pertaining to lab design and construction, manyarchitects, unfortunately, choose to avoid what can be one of themost profitable and professionally rewarding areas ofspecialization. Written by an architect with more than thirty-three years ofexperience as a master planner and programmer of laboratories andclinical facilities, this book demystifies the process oflaboratory planning and design. It provides a comprehensiveoverview of the fundamental issues related to laboratory design andoffers readers detailed, step-by-step guidance through the complexmaze of design specifications and codes, standards, and officialguidelines that must be addressed during the programming, planning,design, and construction process. Focusing mainly on laboratory programming, planning, and designcriteria for "wet" laboratory environments, Leonard Mayer providesexamples from numerous master plans, facility programs, functionalprograms and requirements programs applicable to a wide variety ofscientific and medical disciplines, and related facilities. Relatedfunctions and activities include administrative offices, computercenters, core service and support, building services facilities,and more. He presents new and updated design criteria based onrecent laws and regulations and supplies readers with comprehensivelists of relevant codes, regulations, standards, guidelines, andarchitectural, structural, mechanical, electrical, and plumbingcriteria. Design and Planning of Research and Clinical Laboratory Facilitiesis an excellent primer for architecture students and newcomers tothe field, as well as an indispensable single-volume reference forexperienced professionals. It is also an invaluable resource forresearchers and investigators, facility planners and managers,plant engineers, and all others involved with the design,construction, maintenance, and administration of laboratoryfacilities.

Guidelines for Laboratory Design: Health and Safety Considerations, Third Edition provides reliable design information related to specific health and safety issues that need to be considered when building or renovating laboratories.".

Design That Cares: Planning Health Facilities for Patients and Visitors, 3rd Edition is the award-winning, essential textbook and guide for understanding and achieving customer-focused, evidence-based health care design excellence. This updated third edition includes new information about how all aspects of health facility design – site planning, architecture, interiors, product design, graphic design, and others - can meet the needs and reflect the preferences of customers: patients, family and visitors, as well as staff. The book takes readers on a journey through a typical health facility and discusses, in detail, at each stop along the way, how design can demonstrate care both for and about patients and visitors. Design that Cares provides the definitive roadmap to improving customer experience by design.

A respected resource for decades, the Guide for the Care and Use of Laboratory Animals has been updated by a committee of experts, taking into consideration input from the scientific and laboratory animal communities and the public at large. The Guide incorporates new scientific information on common laboratory animals, including aquatic species, and includes extensive references. It is organized around major components of animal use: Key concepts of animal care and use. The Guide sets the framework for the humane care and use of laboratory animals. Animal care and use program. The Guide discusses the concept of a broad Program of Animal Care and Use, including roles and responsibilities of the Institutional Official, Attending Veterinarian and the Institutional Animal Care and Use Committee. Animal environment, husbandry, and management. A chapter on this topic is now divided into sections on terrestrial and aquatic animals and provides recommendations for housing and environment, husbandry, behavioral and population management, and more. Veterinary care. The Guide discusses veterinary care and the responsibilities of the Attending Veterinarian. It includes recommendations on animal procurement and transportation, preventive medicine (including animal biosecurity), and clinical care and management. The Guide addresses distress and pain recognition and relief, and issues surrounding euthanasia. Physical plant. The Guide identifies design issues, providing construction guidelines for functional areas; considerations such as drainage, vibration and noise control, and environmental monitoring; and specialized facilities for animal housing and research needs. The Guide for the Care and Use of Laboratory Animals provides a framework for the judgments required in the management of animal facilities. This updated and expanded resource of proven value will be important to scientists and researchers, veterinarians, animal care personnel, facilities managers, institutional administrators, policy makers involved in research issues, and animal welfare advocates.

The academic biomedical research community is a hub of employment, economic productivity, and scientific progress. Academic research institutions are drivers of economic development in their local and state economies and, by extension, the national economy. Beyond the economic input that the academic biomedical research community both receives and provides, it generates knowledge that in turn affects society in myriad ways. The United States has experienced and continues to face the threat of disasters, and, like all entities, the academic biomedical research community can be affected. Recent disasters, from hurricanes to cyber-attacks, and their consequences have shown that the investments of the federal government and of the many other entities that sponsor academic research are not uniformly secure. First and foremost, events that damage biomedical laboratories and the institutions that house them can have impacts on the safety and well-being of humans and research animals. Furthermore, disasters can affect career trajectories, scientific progress, and financial stability at the individual and institutional levels. Strengthening the Disaster Resilience of the Academic Biomedical Research Community offers recommendations and guidance to enhance the disaster resilience of the academic biomedical research community, with a special focus on the potential actions researchers, academic research institutions, and research sponsors can take to mitigate the impact of future disasters.

“Although the live-work concept is now accepted among progressive urban design and planning professionals, the specifics that define the term, and its application, remain sketchy. This encyclopedic work is sure to change that, providing the critical information that is needed by architects, planners and citizens.” -Peter Katz, Author, The New Urbanism, and Planning Director, Arlington County, Virginia Live-Work Planning and Design is the only comprehensive guide to the design and planning of live-work spaces for architects, designers, and urban planners. Readers will learn from built examples of live-work, both new construction and renovation, in a variety of locations. Urban planners, developers, and economic development staff will learn how various municipalities have developed and incorporated live-work within building codes and city plans. The author, whose pioneering website, www.live-work.com, has been guiding practitioners and users of live-work since 1998, is the United States' leading expert on the subject.

Laboratory Animal Medicine is a compilation of papers that deals with the diseases and biology of major species of animals used in medical research. The book discusses animal medicine, experimental methods and techniques, design and management of animal facilities, and legislation on laboratory animals. Several papers discuss the biology and diseases of mice, hamsters, guinea pigs, and rabbits. Another paper addresses the dog and cat as laboratory animals, including sourcing of these animals, housing, feeding, and their nutritional needs, as well as breeding and colony management. The book also describes ungulates as laboratory animals, including topics on sourcing, husbandry, preventive medical treatments, and housing facilities. One paper addresses primates as test animals, covering the biology and diseases of old world primates, Cebidae, and ferrets. Some papers pertain to the treatment, diseases, and needed facilities for birds, amphibians, and fish. Other papers then deal with techniques of experimentation, anesthesia, euthanasia, and some factors (spontaneous diseases) that complicate animal research. The text can prove helpful for scientists, clinical assistants, and researchers whose work involves laboratory animals.

Responsability for the care of experimental animals. Laboratory animal facilities. The environament. Farm animal cafilities and environment. Laboratory animal care. Special practices. Health and safety responsabilities. Standards for experimental animal surgery. Anesthesia. Euthanasia.

Written by an expert who is the architect of the University of Virginia, Building Type Basics for College and University Facilities provides an updated essential guide to the design of college and university buildings. Featuring contributions from notable architecture and design expects, this second edition includes a number of new examples of college and university buildings completed this century as well as significant new content, including information on sustainability, preservation, technology, and the influence of interdepartmental collaboration on the built environment.

A comprehensive overview of edible landscapes—completewith more than 300 full-color photos and illustrations Designing Urban Agriculture is about the intersection ofecology, design, and community. Showcasing projects and designersfrom around the world who are forging new paths to the sustainablecity through urban agriculture landscapes, it creates a dialogue onthe ways to invite food back into the city and pave a path tohealthier communities and environments. This full-color guide begins with a foundation of ecologicalprinciples and the idea that the food shed is part of a city'surban systems network. It outlines a design process based onsystems thinking and developed for a lifecycle orregenerative-based approach. It also presents strategies, tools,and guidelines that enable informed decisions on planning,designing, budgeting, constructing, maintaining, marketing, andincreasing the sustainability of this re-invented cityscape. Casestudies demonstrate the environmental, economic, and social valueof these landscapes and reveal paths to a greener and healthierurban environment. This unique and indispensable guide: Details how to plan, design, fund, construct, and leverage thesustainability aspects of the edible landscape typology Covers over a dozen typologies including community gardens,urban farms, edible estates, green roofs and vertical walls, edibleschool yards, seed to table, food landscapes within parks, plazas,streetscapes and green infrastructure systems and more Explains how to design regenerative edible landscapes thatbenefit both community and ecology and explores the connectionsbetween food, policy, and planning that promote viable food shedsystems for more resilient communities Examines the integration of management, maintenance, andoperations issues Reveals how to create a business model enterprise thataddresses a lifecycle approach