Peyronie’s Disease: Pathophysiology and Treatment

Peyronie's Disease: Pathophysiology and Treatment combines the basic research of Peyronie’s Disease with an overview of the clinical and practical management of the disease, providing the most comprehensive approach. Coverage includes etiology and psychological aspects of the disease, management according to European and US guidelines for both surgical and non-surgical treatments, and oral therapies and on-going research including stem cells. This book is perfect for urologists—particularly those who specialize in sexual medicine and/or infertility—and for Andrologists and Endocrinologists. Provides a clear understanding of the underlying pathological mechanisms present in Peyronie’s Disease Translates current research in the field into actionable items for a better understanding of the clinical aspects of Peyronie’s Disease Combines knowledge from the perspectives of Urologists, Andrologists and Endocrinologists, giving a comprehensive overview of Peyronie’s Disease

In this guidebook, international authorities review the current nonsurgical and surgical therapeutic options for dealing with Peyronie's disease. A variety of state-of-the-art research techniques is discussed. As the first medical text on the subject, this book provides an up-to-date summary of the etiology, natural history, and pathophysiology of this disease. Also discussed are the many misconceptions about Peyronie's disease.

Although impotence may be the most widely recognized manifestation of male sexual dysfunction, many other forms of sexual disorders do not involve the erectile mechanism, from deficiencies of desire to disturbances in ejaculatory function to the failure of detumescence. With such a myriad-and often co-existing-number of disorders, the successful tr

At last there is on the market a comprehensive reference and practical guide on the application of US to penile diseases and conditions. This is quite simply the most extensive textbook on the subject. After introductory chapters on technical requirements and penile anatomy, subsequent chapters offer a systematic overview of the diverse applications of color Doppler US.

Internationally lauded as the preeminent text in the field, Campbell-Walsh Urology continues to offer the most comprehensive coverage of every aspect of urology. Perfect for urologists, residents, and practicing physicians alike, this updated text highlights all of the essential concepts necessary for every stage of your career, from anatomy and physiology through the latest diagnostic approaches and medical and surgical treatments. The predominant reference used by The American Board of Urology for its examination questions. Algorithms, photographs, radiographs, and line drawings illustrate essential concepts, nuances of clinical presentations and techniques, and decision making. Key Points boxes and algorithms further expedite review. Features hundreds of well-respected global contributors at the top of their respective fields. A total of 22 new chapters, including Evaluation and Management of Men with Urinary Incontinence; Minimally-Invasive Urinary Diversion; Complications Related to the Use of Mesh and Their Repair; Focal Therapy for Prostate Cancer; Adolescent and Transitional Urology; Principles of Laparoscopic and Robotic Surgery in Children; Pediatric Urogenital Imaging; and Functional Disorders of the Lower Urinary Tract in Children. Previous edition chapters have been substantially revised and feature such highlights as new information on prostate cancer screening, management of non–muscle invasive bladder cancer, and urinary tract infections in children. Includes new guidelines on interstitial cystitis/bladder pain syndrome, uro-trauma, and medical management of kidney stone disease. Anatomy chapters have been expanded and reorganized for ease of access. Boasts an increased focus on robotic surgery, image-guided diagnostics and treatment, and guidelines-based medicine. Medicine eBook is accessible on a variety of devices.

From the basic science underpinnings to the most recent developments in medical and surgical care, Campbell-Walsh-Wein Urology offers a depth and breadth of coverage you won’t find in any other urology reference. Now in three manageable volumes, the revised 12th Edition is a must-have text for students, residents, and seasoned practitioners, with authoritative, up-to-date content in an intuitively organized, easy-to-read format featuring key points, quick-reference tables, and handy algorithms throughout. Features shorter, more practical chapters that help you find key information quickly. Includes new chapters on Urinary Tract Imaging: Basic Principles of Nuclear Medicine · Ethics and Informed Consent · Incisions and Access · Complications of Urologic Surgery · Urologic Considerations in Pregnancy · Intraoperative Consultation · Special Urologic Considerations in Transgender Individuals · and more. Covers hot topics such as minimally invasive and robotic surgery; advancements in urologic oncology, including innovative therapeutics for personalized medicine; new approaches to male infertility; technological advances for the treatment of stones; and advances in imaging modalities. Incorporates current AUA/EAU guidelines in each chapter as appropriate Updates all chapters with new content, new advances, and current references and best practices. Extensively updated chapters include Urological Immunotherapy, Minimally Invasive Urinary Diversion, and Updated Focal Therapy for Prostate Cancer. Features more than 175 video clips, including all-new videos on perineal ultrasound, abdominoplasty in prune belly syndrome, partial penectomy, low dose rate brachytherapy, and many more. Written and edited by key opinion leaders, reflecting essential changes and controversies in the field.

Chapter 7 Pharmacology of drugs used in premature ejaculation

In recent years, the evolution of noninvasive vascular technology used to investigate macro- and microcirculation in vascular disorders has produced a large amount of information and increased our knowledge of vascular pathophysiology. Andrea Ledda and his clinical research group, well known to their international colleagues, describe new developments, trends and techniques in andrology and stress the importance of vascular disorders in erectile dysfunction and varicocele in association with infertility.

This book aims to provide specialists and practitioners with a reliable source of information on all aspects of Peyronie’s disease, which is too often still considered a mysterious condition. The focus is in particular on those aspects of the disease that are most hotly debated, including etiology, risk factors, nosology, natural history and medical therapy. Clear guidance is also provided on surgical techniques, with explanation of why and when to apply plication surgery, corporoplasty and plaque surgery and the best approach to complicated cases. Throughout, strenuous efforts have been made to ensure clarity and simplicity of expression and ease of consultation. While clear international guidelines are lacking, this has allowed the authors to devote much space to personal ideas, conveying the fascinating and sometimes conflicting nature of this field of medicine and, hopefully, stimulating further research.

Oncothermia is the next generation medical innovation that delivers selective, controlled and deep energy for cancer treatment. The basic principles for oncothermia stem from oncological hyperthermia, the oldest approach to treating cancer. Nevertheless, hyperthermia has been wrought with significant controversy, mostly stemming from shortcomings of controlled energy delivery. Oncothermia has been able to overcome these insufficiencies and prove to be a controlled, safe and efficacious treatment option. This book is the first attempt to elucidate the theory and practice of oncothermia, based on rigorous mathematical and biophysical analysis, not centered on the temperature increase. It is supported by numerous in-vitro and in-vivo findings and twenty years of clinical experience. This book will help scientists, researchers and medical practitioners in understanding the scientific and conceptual underpinnings of oncothermia and will add another valuable tool in the fight against cancer. Professor Andras Szasz is the inventor of oncothermia and the Head of St Istvan University's Biotechnics Department in Hungary. He has published over 300 papers and lectured at various universities around the world. Dr. Oliver Szasz is the managing director of Oncotherm, the global manufacturer and distributor of medical devices for cancer treatment used in Europe & Asia since the late 1980s. Dr. Nora Szasz is currently a management consultant in healthcare for McKinsey & Co.

Dr. Culley Carson provides a state-of-the-art review of clinical issues surrounding erectile dysfunction. Top experts in the field, like Dr. Laurence Levine and Dr. Alan Seftel, contribute reviews on peyronie's disease and epidemiology and risk factors, respectively. A practical approach is given, with articles on doppler blood flow analysis, comparison of established agents with newer phosphodiesterase medications, penile rehabilitation after prostate cancer, and treatment of erectile dysfunction and depression.

Offering a comprehensive guide, the Oxford Textbook of Urological Surgery is a practical resource mapped to the curriculum for urological training as approved by the General Medical Council (GMC), making it particularly useful in preparation for the Intercollegiate Examination. Presented in a clear and accessible way, this evidence based volume covers all major areas, including functional urology, stone disease, infection, andrology, nephrology, transplantation, uroradiology, and paediatric urology. This highly illustrated full colour textbook has an innovative and user-friendly style, including over 500 photographs, clinical images, and line drawings. Bringing together the expertise of over 100 specialist contributors in the field, the Oxford Textbook of Urological Surgery is a highly valuable source of information, and will become the standard reference text for all who study urological disease and its treatment.

With sweeping revisions throughout, the new edition of Urologic Surgical Pathology equips you to accurately diagnose specimens of the entire urinary tract and male reproductive system plus the adrenal glands. Comprehensive in scope, this title begins with a look at normal anatomy and histology for each organ system...followed by discussions of the pathology of congenital anomalies, inflammations, non-neoplastic diseases and neoplasia. Practical guidance in daily urological pathology sign-out and the latest recommended diagnostic approaches — with an emphasis on clinicopathologic and radiographic-pathologic correlations — makes this a true diagnostic decision-making medical reference. A consistent format enables you to locate critical information quickly, and more than 1600 high-quality illustrations — most in full color — make diagnosis even easier. Consult this title on your favorite e-reader, conduct rapid searches, and adjust font sizes for optimal readability. Rely on the practice-proven experience of today’s authorities to identify and diagnose with confidence. Confirm your diagnostic suspicions by comparing your findings to more than 1600 color images and color graphics. Quickly locate the specific information you need through an abundance of tables, diagrams and flowcharts; boxed lists of types and causes of diseases; differential diagnosis; characteristic features of diseases; complications; classifications; and staging. Stay current with the latest information on: differential diagnosis for all tumor types encountered in urological surgical pathology practice; urologic tumor specimen handling and reporting guidelines; new entities and updated classification schemes; and newer immunohistochemical and genetic diagnostic methods. Develop targeted therapy specific to a particular patient’s problem based on key molecular aspects of disease, especially in relevance to targeted therapy/personalized medicine. Provide the clinician with the most accurate diagnostic and prognostic indicators, by incorporating the latest classification and staging systems in your reports. Deepen your understanding of new diagnostic biomarkers and their utility in differential diagnosis.

The psychological and physical pain of Peyronie's disease is addressed with quiet sympathy in this overview of the most-asked questions urologists hear from patients being treated for its symptoms. The role of the disease in erectile dysfunction is clearly outlined, and such treatments as injections, ionospheres (EDMA), shock waves, stretching therapy, and topical medications are explained. For more debilitating cases, surgical approaches such as grafting, plication, and prosthesis implantation are discussed, with advice about seeking good medical evaluations in order to assess the surgical options. Interesting case studies are presented in the final chapter, and a glossary and list of resources are also included.

Provides an authoritative, comprehensive and clinically-orientated guide to both the background causes and full range of treatment options for patients suffering from impotence and sexually-related dysfunction. The book is a concise and practical text, enhanced with specially commissioned computer graphics and full color illustrations. It is one of the first titles to comprehensively cover the new developments in treatment of female sexual dysfunction. Throughout, there is a wealth of information on new therapies, and the very latest information on drug treatment. The book includes innovative treatment algorithms, summary boxes, and patient vignettes, and has been produced to a tight time-frame to ensure a current approach. Encompasses the very latest developments in the field, thanks to an especially brief production schedule. Discusses the neuroanatomy and physiology of male and female sexual response, and evaluates the role of factors such as hormones, diabetes, hypertension, and depression in causing sexual dysfunction. Explores new oral therapies for male and female sexual dysfunction · new therapies for ejaculation dis¬orders, including rapid ejaculation · MUSE and intracavernosal therapies · vacuum devices, gels, injections, and penile implants · gene therapy · and future directions in treatment. Presents specially commissioned computer graphics and full-color illustrations that make pathophysiology and treatment principles easy to understand.

Make optimal use of the newest techniques, technologies, and treatments with Sleisenger and Fordtran's Gastrointestinal and Liver Disease - the indispensable information source in this broad field! Edited by Mark Feldman, MD, Lawrence S. Friedman, MD, and Lawrence J. Brandt, MD, this 9th Edition equips you with the amassed knowledge of hundreds of respected authorities from around the world, helping you to overcome all of your most complex clinical challenges and make the most effective use of the newest techniques, technologies, and treatments. Significant updates on bariatric surgery, Barrett's esophagus, and many other evolving areas keep your practice current. Full-text online access includes downloadable illustrations and links to reference abstracts. The result remains the indispensable core reference in gastroenterology and hepatology. World-renowned experts provide reliable guidance on every area of your field. A consistent, full-color chapter design lets you find information quickly. Significant updates on bariatric surgery, Barrett's esophagus, endoscopic ultrasound, endosonography, treatment of liver disease, and much more keep you current on the latest advances. Many new contributors from all over the world provide you with fresh insights on all areas of gastroenterology and hepatology. Full-text online access via Expert Consult includes downloadable illustrations and links to reference abstracts.

Abdominal Imaging, a title in the Expert Radiology Series, edited by Drs. Dushyant Sahani and Anthony Samir, is a comprehensive reference that encompasses both GI and GU radiology. It provides richly illustrated, advanced guidance to help you overcome the full range of diagnostic, therapeutic, and interventional challenges in abdominal imaging and combines an image-rich, easy-to-use format with the greater depth that experienced practitioners need. Select the best imaging approaches and effectively interpret your findings by comparing them to thousands of images that represent every modality and every type of abdominal imaging. Find detailed, expert guidance on all diagnostic, therapeutic, and interventional aspects of abdominal imaging in one authoritative source, including challenging topics such as Oncologic Assessment of Tumor Response and How to Scan a Difficult Patient. Efficiently locate the information you need with a highly templated, well-organized, at-a-glance organization.

In this guidebook, international authorities review the current nonsurgical and surgical therapeutic options for dealing with Peyronie's disease. A variety of state-of-the-art research techniques is discussed. As the first medical text on the subject, this book provides an up-to-date summary of the etiology, natural history, and pathophysiology of this disease. Also discussed are the many misconceptions about Peyronie's disease.