Peyronie’s Disease: Pathophysiology and Treatment

Peyronie's Disease: Pathophysiology and Treatment combines the basic research of Peyronie’s Disease with an overview of the clinical and practical management of the disease, providing the most comprehensive approach. Coverage includes etiology and psychological aspects of the disease, management according to European and US guidelines for both surgical and non-surgical treatments, and oral therapies and on-going research including stem cells. This book is perfect for urologists—particularly those who specialize in sexual medicine and/or infertility—and for Andrologists and Endocrinologists. Provides a clear understanding of the underlying pathological mechanisms present in Peyronie’s Disease Translates current research in the field into actionable items for a better understanding of the clinical aspects of Peyronie’s Disease Combines knowledge from the perspectives of Urologists, Andrologists and Endocrinologists, giving a comprehensive overview of Peyronie’s Disease

In this guidebook, international authorities review the current nonsurgical and surgical therapeutic options for dealing with Peyronie's disease. A variety of state-of-the-art research techniques is discussed. As the first medical text on the subject, this book provides an up-to-date summary of the etiology, natural history, and pathophysiology of this disease. Also discussed are the many misconceptions about Peyronie's disease.

Although impotence may be the most widely recognized manifestation of male sexual dysfunction, many other forms of sexual disorders do not involve the erectile mechanism, from deficiencies of desire to disturbances in ejaculatory function to the failure of detumescence. With such a myriad-and often co-existing-number of disorders, the successful tr

Offering a comprehensive guide, the Oxford Textbook of Urological Surgery is a practical resource mapped to the curriculum for urological training as approved by the General Medical Council (GMC), making it particularly useful in preparation for the Intercollegiate Examination. Presented in a clear and accessible way, this evidence based volume covers all major areas, including functional urology, stone disease, infection, andrology, nephrology, transplantation, uroradiology, and paediatric urology. This highly illustrated full colour textbook has an innovative and user-friendly style, including over 500 photographs, clinical images, and line drawings. Bringing together the expertise of over 100 specialist contributors in the field, the Oxford Textbook of Urological Surgery is a highly valuable source of information, and will become the standard reference text for all who study urological disease and its treatment.

This book aims to provide specialists and practitioners with a reliable source of information on all aspects of Peyronie’s disease, which is too often still considered a mysterious condition. The focus is in particular on those aspects of the disease that are most hotly debated, including etiology, risk factors, nosology, natural history and medical therapy. Clear guidance is also provided on surgical techniques, with explanation of why and when to apply plication surgery, corporoplasty and plaque surgery and the best approach to complicated cases. Throughout, strenuous efforts have been made to ensure clarity and simplicity of expression and ease of consultation. While clear international guidelines are lacking, this has allowed the authors to devote much space to personal ideas, conveying the fascinating and sometimes conflicting nature of this field of medicine and, hopefully, stimulating further research.

Oncothermia is the next generation medical innovation that delivers selective, controlled and deep energy for cancer treatment. The basic principles for oncothermia stem from oncological hyperthermia, the oldest approach to treating cancer. Nevertheless, hyperthermia has been wrought with significant controversy, mostly stemming from shortcomings of controlled energy delivery. Oncothermia has been able to overcome these insufficiencies and prove to be a controlled, safe and efficacious treatment option. This book is the first attempt to elucidate the theory and practice of oncothermia, based on rigorous mathematical and biophysical analysis, not centered on the temperature increase. It is supported by numerous in-vitro and in-vivo findings and twenty years of clinical experience. This book will help scientists, researchers and medical practitioners in understanding the scientific and conceptual underpinnings of oncothermia and will add another valuable tool in the fight against cancer. Professor Andras Szasz is the inventor of oncothermia and the Head of St Istvan University's Biotechnics Department in Hungary. He has published over 300 papers and lectured at various universities around the world. Dr. Oliver Szasz is the managing director of Oncotherm, the global manufacturer and distributor of medical devices for cancer treatment used in Europe & Asia since the late 1980s. Dr. Nora Szasz is currently a management consultant in healthcare for McKinsey & Co.

Erectile dysfunction can affect all age groups. Numerous physical and emotional risk factors may contribute to the problem. These risk factors can range from chronic diseases and medications to psychological factors. In the U.S. alone, it has been estimated that 18 to 30 million men suffer from erectile dysfunction. This number has increased significantly as awareness of the disorder has heightened. Researchers and health care professionals now have a better understanding of what causes erectile dysfunction and the effective medications and non-medication treatments used to treat the condition. Comprehensive and state-of-the-art, Contemporary Treatment of Erectile Dysfunction: A Clinical Guide synthesizes the literature and covers all aspects of treating erectile dysfunction and other related male sexual dysfunctions. This invaluable title offers all physicians, residents, and fellows -- and even medical students and other health professionals such as nurse practitioners and physician assistants – an essential reference for enhancing diagnosis and treatment of this debilitating disorder.

At last there is on the market a comprehensive reference and practical guide on the application of US to penile diseases and conditions. This is quite simply the most extensive textbook on the subject. After introductory chapters on technical requirements and penile anatomy, subsequent chapters offer a systematic overview of the diverse applications of color Doppler US.

This book is based on results of the 2010 International Symposium on Dupuytren's disease held in Miami, Florida, but it also includes new data and additional chapters. It is hoped that it will raise awareness of this underestimated condition and promote cooperative efforts to work towards a cure. Up to date information is provided on the epidemiology, biology, and pathology of the disease. The principles and specifics of treatment are explored in detail. The indications for and techniques of radiotherapy, minimally invasive treatments and open surgery are fully explained. The role of physical therapy is considered as well as the care of relapse and complications. The treatment of Ledderhose’s disease and Peyronie’s disease is also discussed. This book provides invaluable information for hand surgeons, podiatrists, orthopedists, radiation therapy specialists and general practitioners. It will help to foster an interdisciplinary approach to the understanding and management of this debilitating disorder.

This volume discusses the background and various clinical applications of radiation therapy in the treatment of non-malignant diseases. It documents the radiobiological and physical principles of treatment and the rationale underlying the use of radiotherapy for various disorders of the CNS, head and neck, eye, skin and soft tissues, bone and joints, and vascular system. In so doing, it draws attention to and elucidates the scope for application of radiotherapy beyond the treatment of malignancies. Both the risks and the benefits of such treatment are fully considered, the former ranging from minor clinical problems to life-threatening diseases.

This textbook provides a guide to reconstructive surgery of genitourethral problems in male patients. The first section covers all aspects of urethral reconstruction, including the functional anatomy of the urethra, etiology, epidemiology, and demographic differences in urethral pathology. The second section focuses on surgical reconstruction of penile and scrotal anomalies and dysfunctions. Textbook of Male Genitourethral Reconstruction aims to aid the management of male genitourethral reconstruction patients by reviewing the recent advancements in technology and surgical technique. This book is relevant to urologists, plastic and reconstructive surgeons, medical students, and health care professionals working within urology and plastic surgery.

The book reviews the main approaches for generation of differentiated cells from various types of stem cells, including embryonic, placental and cord blood stem cells through marrow, adipose tissue and dental pulp. The book starts with an overview of experimental protocols applied to generate insulin secreting cells, neural cells, heart cells, and other tissue specific cells ex vivo and in experimental animals. This is followed by exhaustive review of clinical trials in these pathologies. It continues with a comparison of the merits of successful transplantation in humans versus animal experimentation, and highlights the most promising clinical applications in the field. Special chapters are devoted to the topic of tissue engineering and modern synthetic and biological scaffolds. It is essential reading for scientists and researchers in tissue engineering and stem cell research as well as clinicians who are involved in developing or testing stem cell therapies.

Lower urinary tract dysfunction (LUTD) is an umbrella diagnosis that covers the abnormalities of anatomy and function in the bladder, urethra, and, in men, the prostate. People with LUTD face a number of social, mental, and physical health effects due to the symptoms. Despite the increasing evidence in the assessment and management of lower urinary tract symptoms, it remains a challenge to bridge the gap between research evidence and clinical practice. In this book, each and every one of the authors presents a remarkable work for how to apply the evidence to clinical practice from different aspects. I hope this book is a key for every reader to open the door to LUTD.

This book is a printed edition of the Special Issue "Recent Advances in Scar Biology" that was published in IJMS

This book is designed to meet the needs of nurse practitioners, advanced practice nurses and also physician assistants, working in urology. The full range of domains of practice is covered, including assessment and diagnosis, clinical management, nurse practitioner and patient relationships, consultation, health promotion and disease prevention, and practice management and research. Some background knowledge is assumed regarding the normal anatomy and physiology of the genitourinary system and the pathophysiology underlying specific urologic health-related problems. The Nurse Practitioner in Urology will be invaluable in ensuring that the nurse practitioner is able to maintain exemplary management of patients with acute and chronic urologic conditions in a wide variety of settings, including independent practices, hospitals, and academic urologic practices. It explains fully the role of the nurse practitioner as a skilled clinician in urology, blending nursing and medical management and capable of managing many chronic nonoperative urologic conditions while recognizing those conditions which may benefit from surgical management. As populations continue to age worldwide, there is no doubt that the provision of advanced urologic care by nurse practitioners is an area that will continue to expand, benefiting from additional training and expertise. ​

Glenn's Urologic Surgery is a comprehensive but concise textbook focused on surgical procedures. After more than 30 years it is still required reading for most urology residents and is consulted by practicing physicians while planning surgeries. Chapters are heavily illustrated and progress from diagnosis to indications for surgery, to brief sections on alternative therapies, and then to detailed sections on surgical technique before closing with a discussion of outcomes as found in the literature. The Seventh Edition continues to emphasize laparoscopic procedures. Each section opens with a thoroughly illustrated description of relevant anatomy.

The therapeutic potential of the use of adipose stem cells in regenerative medicine has been increasingly recognized, and in recent years concrete clinical benefits have accrued as these cells have been explored for a variety of applications. This readable and informative textbook tracks the progress that has been made in this fascinating new area of biomedicine. All aspects of the subject are considered, with particular attention to adipose cell biology, adipose tissue engineering strategies, and the diverse clinical applications of adipose stem cells. Funding issues, industrial approaches, regulatory challenges, and future directions are also examined. The two editors have vast experience in the field and have chosen leading experts from different countries to write on each topic. This book will excite the interest of all researchers, clinicians, and students wishing to gain an in-depth understanding of adipose stem cells and their flourishing role in regenerative medicine.

The average physician and even cancer care-givers are not knowledgeable about the effects of cancer treatment on sex and reproductive life. They are even less aware of the options available for treatment of such patients. Cancer and Sexual Health fills a great need for a reference work devoted to the link between cancer and human sexuality. The volume is designed to give a comprehensive and state-of-the-art review of the sexual and reproductive consequences of cancer diagnosis and treatment. It will prove an invaluable resource for those clinicians caring for cancer patients as well as acting as a reference text for the sexual medicine clinician who may not see a large number of cancer patients.

The psychological and physical pain of Peyronie's disease is addressed with quiet sympathy in this overview of the most-asked questions urologists hear from patients being treated for its symptoms. The role of the disease in erectile dysfunction is clearly outlined, and such treatments as injections, ionospheres (EDMA), shock waves, stretching therapy, and topical medications are explained. For more debilitating cases, surgical approaches such as grafting, plication, and prosthesis implantation are discussed, with advice about seeking good medical evaluations in order to assess the surgical options. Interesting case studies are presented in the final chapter, and a glossary and list of resources are also included.

This book fulfils the need for a general urology text primarily urologists in training. It has a novel format by having a clinical chapter always preceded by a scientific foundation chapter. The scientific chapter is geared toward answering questions for boards and understanding pathophysiology, is concise and relevant. The clinical chapter is written around evidence-based medicine and in "how-to" format with algorithms, with reference to AUA & EAU guidelines, well illustrated.