Personalized and Stratified Therapy in Epilepsy

Personalized and Stratified Therapy in Epilepsy
Author: Sara Eyal,Dana Ekstein
Publsiher: Academic Press
Total Pages: 450
Release: 2020-12-15
ISBN 10: 9780128173466
ISBN 13: 0128173467
Language: EN, FR, DE, ES & NL

Personalized and Stratified Therapy in Epilepsy Book Review:

Personalized Treatment in Epilepsy highlights the individualized- and subgroup-based approaches in diagnosing, treating, and monitoring epilepsy. Whereas the term 'personalized medicine' is used to describe the focus on individual patients, 'stratified medicine' refers to the definition of population subgroups based on estimates of their differences in the etiology and prognosis of epilepsy, or response to treatment. The book describes the various aspects of personalized and stratified approaches in epilepsy, the potential of these approaches to improve the cost-effectiveness of epilepsy treatment, and barriers to their implementation. The book assists clinicians in rationally choosing the required diagnostic and treatment means for their patients, out of the abundance of available technologies and products. By doing so, they will provide better care, mitigating adverse events, expediting the reach of effective treatment, and reducing costs. The target audience is anyone involved in developing and delivering diagnostic means and treatment for people with epilepsy, including epileptologists, other neurologists, neurosurgeons, pharmacists, nurses, technicians, geneticists, researchers Comprehensively describes individualized and stratified treatment approaches in epilepsy Assists clinicians with rationally choosing the required diagnostic and treatment means for their patients Diagnosis, drugs, non-pharmacological treatments, and future research are all discussed in depth

Textbook of Personalized Medicine

Textbook of Personalized Medicine
Author: Kewal K. Jain
Publsiher: Springer Nature
Total Pages: 744
Release: 2020-12-05
ISBN 10: 3030620808
ISBN 13: 9783030620806
Language: EN, FR, DE, ES & NL

Textbook of Personalized Medicine Book Review:

This book is for personalized medicine as a prescription of specific treatments and therapeutics best suited for an individual and considers genetic as well as environmental factors that influence responses to therapy. Best approaches are described for integration of all available technologies for optimizing the therapy of individual patients. This comprehensive third edition covers the latest advances in personalized medicine and several chapters are devoted to various specialties, particulary cancer which is the largest area of application. The book discusses the development of personalized medicine and various players in it such as companies, academic institutions, the government, and the public as the consumer of healthcare. Additionally, the roles of bioinformatics, electronic health records, and digital technologies for personalized medicine are discussed. Textbook of Personalized Medicine, 3rd Edition serves as a convenient source of information for students at many levels and in a wide range of fields, including physicians, scientists, and decision makers in the biopharmaceutical and healthcare industries.

Genomic and Personalized Medicine

Genomic and Personalized Medicine
Author: Anonim
Publsiher: Academic Press
Total Pages: 1558
Release: 2008-11-11
ISBN 10: 9780080919034
ISBN 13: 0080919030
Language: EN, FR, DE, ES & NL

Genomic and Personalized Medicine Book Review:

This two-volume set — winner of a 2013 Highly Commended BMA Medical Book Award for Medicine — provides an in-depth look at one of the most promising avenues for advances in the diagnosis, prevention and treatment of human disease. The inclusion of the latest information on diagnostic testing, population screening, predicting disease susceptibility, pharmacogenomics and more presents this book as an essential tool for both students and specialists across many biological and medical disciplines, including human genetics and genomics, oncology, neuroscience, cardiology, infectious disease, molecular medicine, and biomedical science, as well as health policy disciplines focusing on ethical, legal, regulatory and economic aspects of genomics and medicine. Volume One Includes: Principles, Methodology and Translational Approaches, takes readers on the journey from principles of human genomics to technology, informatic and computational platforms for genomic medicine, as well as strategies for translating genomic discoveries into advances in personalized clinical care. Volume Two Includes: Genome Discoveries and Clinical Applications presents the latest developments in disease-based genomic and personalized medicine. With chapters dedicated to cardiovascular disease, oncology, inflammatory disease, metabolic disease, neuropsychiatric disease, and infectious disease, this work provides the most comprehensive guide to the principles and practice of genomic and personalized medicine. Highly Commended 2013 BMA Medical Book Award for Medicine Contributions from leaders in the field provide unparalleled insight into current technologies and applications in clinical medicine. Full colour throughout enhances the utility of this work as the only available comprehensive reference for genomic and personalized medicine. Discusses scientific foundations and practical applications of new discoveries, as well as ethical, legal/regulatory, and social issues related to the practice of genomic medicine.

Personalized Psychiatry

Personalized Psychiatry
Author: Bernhard Baune
Publsiher: Academic Press
Total Pages: 604
Release: 2019-10-16
ISBN 10: 0128131772
ISBN 13: 9780128131770
Language: EN, FR, DE, ES & NL

Personalized Psychiatry Book Review:

Personalized Psychiatry presents the first book to explore this novel field of biological psychiatry that covers both basic science research and its translational applications. The book conceptualizes personalized psychiatry and provides state-of-the-art knowledge on biological and neuroscience methodologies, all while integrating clinical phenomenology relevant to personalized psychiatry and discussing important principles and potential models. It is essential reading for advanced students and neuroscience and psychiatry researchers who are investigating the prevention and treatment of mental disorders. Combines neurobiology with basic science methodologies in genomics, epigenomics and transcriptomics Demonstrates how the statistical modeling of interacting biological and clinical information could transform the future of psychiatry Addresses fundamental questions and requirements for personalized psychiatry from a basic research and translational perspective

The Comorbidities of Epilepsy

The Comorbidities of Epilepsy
Author: Marco Mula
Publsiher: Academic Press
Total Pages: 413
Release: 2019-04-20
ISBN 10: 0128148780
ISBN 13: 9780128148785
Language: EN, FR, DE, ES & NL

The Comorbidities of Epilepsy Book Review:

Epilepsy is one of most frequent neurological disorders affecting about 50 million people worldwide and 50% of them have at least another medical problem in comorbidity; sometimes this is a the cause of the epilepsy itself or it is due to shared neurobiological links between epilepsy and other medical conditions; other times it is a long-term consequence of the antiepileptic drug treatment. The Comorbidities of Epilepsy offers an up-to-date, comprehensive overview of all comorbidities of epilepsy (somatic, neurological and behavioral), by international authorities in the field of clinical epileptology, with an emphasis on epidemiology, pathophysiology, diagnosis and management. This book includes also a critical appraisal of the methodological aspects and limitations of current research on this field. Pharmacological issues in the management of comorbidities are discussed, providing information on drug dosages, side effects and interactions, in order to enable the reader to manage these patients safely. The Comorbidities of Epilepsy is aimed at all health professionals dealing with people with epilepsy including neurologists, epileptologists, psychiatrists, clinical psychologists, epilepsy specialist nurses and clinical researchers. Provides a comprehensive overview of somatic, neurological and behavioral co-morbidities of epilepsy Discusses up-to-date management of comorbidities of epilepsy Written by a group of international experts in the field

Adherence to Long term Therapies

Adherence to Long term Therapies
Author: Organisation mondiale de la santé,World Health Organization
Publsiher: World Health Organization
Total Pages: 198
Release: 2003
ISBN 10: 9789241545990
ISBN 13: 9241545992
Language: EN, FR, DE, ES & NL

Adherence to Long term Therapies Book Review:

This report is based on an exhaustive review of the published literature on the definitions, measurements, epidemiology, economics and interventions applied to nine chronic conditions and risk factors.

Molecular and Cellular Therapeutics

Molecular and Cellular Therapeutics
Author: David Whitehouse,Ralph Rapley
Publsiher: John Wiley & Sons
Total Pages: 336
Release: 2012-02-17
ISBN 10: 1119967805
ISBN 13: 9781119967804
Language: EN, FR, DE, ES & NL

Molecular and Cellular Therapeutics Book Review:

Molecular and Cellular Therapeutics aims to bring together key developments in the areas of molecular diagnostics, therapeutics and drug discovery. The book covers topics including diagnostics, therapeutics, model systems, clinical trials and drug discovery. The developing approaches to molecular and cellular therapies, diagnostics and drug discovery are presented in the context of the pathologies they are devised to treat.

Essentials of Genomic and Personalized Medicine

Essentials of Genomic and Personalized Medicine
Author: Geoffrey S. Ginsburg,Huntington F Willard
Publsiher: Academic Press
Total Pages: 850
Release: 2009-10-02
ISBN 10: 9780080958118
ISBN 13: 0080958117
Language: EN, FR, DE, ES & NL

Essentials of Genomic and Personalized Medicine Book Review:

Derived from the comprehensive two-volume set, Genomic and Personalized Medicine also edited by Drs. Willard and Ginsburg, this work serves the needs of the evolving population of scientists, researchers, practitioners and students that are embracing one of the most promising avenues for advances in diagnosis, prevention and treatment of human disease. From principles, methodology and translational approaches to genome discoveries and clinical applications, Essentials of Genomic and Personalized Medicine will be a valuable resource for various professionals and students across medical disciplines, including human genetics and genomics, oncology, neuroscience, gene therapy, molecular medicine, pharmacology, and biomedical sciences. Updates with regard to diagnostic testing, pharmacogenetics, predicting disease susceptibility, and other important research components as well as chapters dedicated to cardiovascular disease, oncology, inflammatory disease, metabolic disease, neuropsychiatric disease, and infectious disease, present this book as an essential tool for a variety of professionals and students who are endeavouring into the developing the diverse and practical field of genomic and personalized medicine. * Full color throughout * Includes contributions on genetic counselling, ethical, legal/regulatory, and social issues related to the practice of genomic medicine from leaders in the field * Introductory chapter highlights differences between personalized and traditional medicine, promising areas of current research, and challenges to incorporate the latest research discoveries and practice * Ancillary material includes case studies and lab questions which highlight the collaborative approach to the science

Personalized Medicine

Personalized Medicine
Author: Barbara Prainsack
Publsiher: NYU Press
Total Pages: 288
Release: 2017-12-19
ISBN 10: 1479856908
ISBN 13: 9781479856909
Language: EN, FR, DE, ES & NL

Personalized Medicine Book Review:

Inside today's data-driven personalized medicine, and the time, effort, and information required from patients to make it a reality Medicine has been personal long before the concept of “personalized medicine” became popular. Health professionals have always taken into consideration the individual characteristics of their patients when diagnosing, and treating them. Patients have cared for themselves and for each other, contributed to medical research, and advocated for new treatments. Given this history, why has the notion of personalized medicine gained so much traction at the beginning of the new millennium? Personalized Medicine investigates the recent movement for patients’ involvement in how they are treated, diagnosed, and medicated; a movement that accompanies the increasingly popular idea that people should be proactive, well-informed participants in their own healthcare. While it is often the case that participatory practices in medicine are celebrated as instances of patient empowerment or, alternatively, are dismissed as cases of patient exploitation, Barbara Prainsack challenges these views to illustrate how personalized medicine can give rise to a technology-focused individualism, yet also present new opportunities to strengthen solidarity. Facing the future, this book reveals how medicine informed by digital, quantified, and computable information is already changing the personalization movement, providing a contemporary twist on how medical symptoms or ailments are shared and discussed in society. Bringing together empirical work and critical scholarship from medicine, public health, data governance, bioethics, and digital sociology, Personalized Medicine analyzes the challenges of personalization driven by patient work and data. This compelling volume proposes an understanding that uses novel technological practices to foreground the needs and interests of patients, instead of being ruled by them.

Causes and Consequences of Intrauterine Growth Restriction

Causes and Consequences of Intrauterine Growth Restriction
Author: Elke Winterhager,Ivo Bendix,Suzanne Lee Miller
Publsiher: Frontiers Media SA
Total Pages: 135
Release: 2020-06-04
ISBN 10: 2889637689
ISBN 13: 9782889637683
Language: EN, FR, DE, ES & NL

Causes and Consequences of Intrauterine Growth Restriction Book Review:

Toward Precision Medicine

Toward Precision Medicine
Author: National Research Council,Division on Earth and Life Studies,Board on Life Sciences,Committee on A Framework for Developing a New Taxonomy of Disease
Publsiher: National Academies Press
Total Pages: 142
Release: 2012-01-16
ISBN 10: 0309222222
ISBN 13: 9780309222228
Language: EN, FR, DE, ES & NL

Toward Precision Medicine Book Review:

Motivated by the explosion of molecular data on humans-particularly data associated with individual patients-and the sense that there are large, as-yet-untapped opportunities to use this data to improve health outcomes, Toward Precision Medicine explores the feasibility and need for "a new taxonomy of human disease based on molecular biology" and develops a potential framework for creating one. The book says that a new data network that integrates emerging research on the molecular makeup of diseases with clinical data on individual patients could drive the development of a more accurate classification of diseases and ultimately enhance diagnosis and treatment. The "new taxonomy" that emerges would define diseases by their underlying molecular causes and other factors in addition to their traditional physical signs and symptoms. The book adds that the new data network could also improve biomedical research by enabling scientists to access patients' information during treatment while still protecting their rights. This would allow the marriage of molecular research and clinical data at the point of care, as opposed to research information continuing to reside primarily in academia. Toward Precision Medicine notes that moving toward individualized medicine requires that researchers and health care providers have access to very large sets of health- and disease-related data linked to individual patients. These data are also critical for developing the information commons, the knowledge network of disease, and ultimately the new taxonomy.

Genomic and Personalized Medicine

Genomic and Personalized Medicine
Author: Geoffrey S. Ginsburg,Huntington F. Willard
Publsiher: Academic Press
Total Pages: 1350
Release: 2012-11-15
ISBN 10: 0123822270
ISBN 13: 9780123822277
Language: EN, FR, DE, ES & NL

Genomic and Personalized Medicine Book Review:

This two-volume set provides an in-depth look at one of the most promising avenues for advances in the diagnosis, prevention and treatment of human disease. The inclusion of the latest information on diagnostic testing, population screening, predicting disease susceptibility, pharmacogenomics and more presents this book as an essential tool for both students and specialists across many biological and medical disciplines, including human genetics and genomics, oncology, neuroscience, cardiology, infectious disease, molecular medicine, and biomedical science, as well as health policy disciplines focusing on ethical, legal, regulatory and economic aspects of genomics and medicine. Volume One Includes: Principles, Methodology and Translational Approaches, takes readers on the journey from principles of human genomics to technology, informatic and computational platforms for genomic medicine, as well as strategies for translating genomic discoveries into advances in personalized clinical care. Volume Two Includes: Genome Discoveries and Clinical Applications presents the latest developments in disease-based genomic and personalized medicine. With chapters dedicated to cardiovascular disease, oncology, inflammatory disease, metabolic disease, neuropsychiatric disease, and infectious disease, this work provides the most comprehensive guide to the principles and practice of genomic and personalized medicine. * Contributions from leaders in the field provide unparalleled insight into current technologies and applications in clinical medicine. * Full colour throughout enhances the utility of this work as the only available comprehensive reference for genomic and personalized medicine. * Discusses scientific foundations and practical applications of new discoveries, as well as ethical, legal/regulatory, and social issues related to the practice of genomic medicine.

Oral and Maxillofacial Surgery E Book

Oral and Maxillofacial Surgery   E Book
Author: Raymond J. Fonseca
Publsiher: Elsevier Health Sciences
Total Pages: 2696
Release: 2017-03-08
ISBN 10: 0323444423
ISBN 13: 9780323444422
Language: EN, FR, DE, ES & NL

Oral and Maxillofacial Surgery E Book Book Review:

This trusted, three-volume resource covers the full scope of oral and maxillofacial surgery with up-to-date, evidence-based coverage of surgical procedures performed today. NEW! Full color design provides a more vivid depiction of pathologies, concepts, and procedures. NEW! Expert Consult website includes all of the chapters from the print text plus "classic" online-only chapters and an expanded image collection, references linked to PubMed, and periodic content updates. NEW! Thoroughly revised and reorganized content reflects current information and advances in OMS. NEW! New chapters on implants and orthognathic surgery cover the two areas where oral and maxillofacial surgeons have been expanding their practice. NEW! Digital formats are offered in addition to the traditional print text and provide on-the-go access via mobile tablets and smart phones.

Personalized Medicine in Relation to Redox State Diet and Lifestyle

Personalized Medicine  in Relation to Redox State  Diet and Lifestyle
Author: Faik Atroshi
Publsiher: BoD – Books on Demand
Total Pages: 214
Release: 2020-10-14
ISBN 10: 1838803696
ISBN 13: 9781838803698
Language: EN, FR, DE, ES & NL

Personalized Medicine in Relation to Redox State Diet and Lifestyle Book Review:

“Personalized Medicine, in Relation to Redox State, Diet and Lifestyle” is a book on the important issues regarding good health and a need for more selective and sensitive systems to identify diseases. It is a complex issue. Presently, in 2020 we have the fight against Coronavirus with high lethality and the world is asking for information on its metabolism, spread and tools to prevent, protect and cure. The complexity of diseases indicate that we must involve diet and lifestyle at the individual level and discuss the possible impact on evolutionary defense systems. We also need to include discussions of the redox state of compounds and this requires collaborations between research areas. The book has gathered interdisciplinary works, joining fields such as trace elements, biochemistry, physiology and analytical chemistry with the aim of finding new approaches to diseases, for example by using individual treatment at the cellular level.

Human Adult Stem Cells

Human Adult Stem Cells
Author: John Masters,Bernhard Ø Palsson
Publsiher: Springer Science & Business Media
Total Pages: 208
Release: 2009-05-30
ISBN 10: 9048122694
ISBN 13: 9789048122691
Language: EN, FR, DE, ES & NL

Human Adult Stem Cells Book Review:

The aim of volume 7 of Human Cell Culture is to provide clear and precise methods for growing primary cultures of adult stem cells from various human tissues and describe culture conditions in which these adult stem cells differentiate along their respective lineages. The book will be of value to biomedical scientists and of special interest to stem cell biologists and tissue engineers. Each chapter is written by experts actively involved in growing human adult stem cells.

Clinical Molecular Medicine

Clinical Molecular Medicine
Author: Dhavendra Kumar
Publsiher: Academic Press
Total Pages: 606
Release: 2019-11-30
ISBN 10: 0128094427
ISBN 13: 9780128094426
Language: EN, FR, DE, ES & NL

Clinical Molecular Medicine Book Review:

Clinical Molecular Medicine: Principles and Practice presents the latest scientific advances in molecular and cellular biology, including the development of new and effective drug and biological therapies and diagnostic methods. The book provides medical and biomedical students and researchers with a clear and clinically relevant understanding on the molecular basis of human disease. With an increased focus on new practice concepts, such as stratified, personalized and precision medicine, this book is a valuable and much-needed resource that unites the core principles of molecular biology with the latest and most promising genomic advances. Illustrates the fundamental principles and therapeutic applications of molecular and cellular biology Offers a clinically focused account of molecular heterogeneity Includes comprehensive coverage of many different disorders, including growth and development, cardiovascular, metabolic, skin, blood, digestive, inflammatory, neuropsychiatric disorders, and many more

Jasper s Basic Mechanisms of the Epilepsies

Jasper s Basic Mechanisms of the Epilepsies
Author: Jeffrey Noebels,Massimo Avoli,Michael Rogawski,Richard Olsen,Antonio Delgado-Escueta
Publsiher: Oxford University Press
Total Pages: 1264
Release: 2012-06-01
ISBN 10: 0199842590
ISBN 13: 9780199842599
Language: EN, FR, DE, ES & NL

Jasper s Basic Mechanisms of the Epilepsies Book Review:

H.H. Jasper, A.A. Ward, A. Pope and H.H. Merritt, chair of the Public Health Service Advisory Committee on the Epilepsies, National Institutes of Health, published the first volume on Basic Mechanisms of the Epilepsies (BME) in 1969. Their ultimate goal was to search for a "better understanding of the epilepsies and seek more rational methods of their prevention and treatment." Since then, basic and clinical researchers in epilepsy have gathered together every decade and a half with these goals in mind -- assessing where epilepsy research has been, what it has accomplished, and where it should go. In 1999, the third volume of BME was named in honor of H.H. Jasper. In line with the enormous expansion in the understanding of basic epilepsy mechanisms over the past four decades, this fourth edition of Jasper's BME is the most ambitious yet. In 90 chapters, the book considers the role of interactions between neurons, synapses, and glia in the initiation, spread and arrest of seizures. It examines mechanisms of excitability, synchronization, seizure susceptibility, and ultimately epileptogenesis. It provides a framework for expanding the epilepsy genome and understanding the complex heredity responsible for common epilepsies as it explores disease mechanisms of ion channelopathies and developmental epilepsy genes. It considers the mechanisms of conditions of epilepsy comorbidities. And, for the first time, this 4th edition describes the current efforts to translate the discoveries in epilepsy disease mechanisms into new therapeutic strategies. This book, considered the 'bible' of basic epilepsy research, is essential for the student, the clinician scientist and all research scientists who conduct laboratory-based experimental epilepsy research using cellular, brain slice and animal models, as well as for those interested in related disciplines of neuronal oscillations, network plasticity, and signaling in brain strucutres that include the cortex, hippocampus, and thalamus. In keeping with the 1969 goals, the book is now of practical importance to the clinical neurologist and epileptologist as the progress of research in molecular genetics and modern efforts to design antiepileptic drugs, cures and repairs in the epilepsies converge and impact clinical care.

Essential Concepts in Molecular Pathology

Essential Concepts in Molecular Pathology
Author: William B. Coleman,Gregory J. Tsongalis
Publsiher: Academic Press
Total Pages: 462
Release: 2010-02-16
ISBN 10: 9780080922188
ISBN 13: 008092218X
Language: EN, FR, DE, ES & NL

Essential Concepts in Molecular Pathology Book Review:

This streamlined "essential" version of the Molecular Pathology (2009) textbook extracts key information, illustrations and photographs from the main textbook in the same number and organization of chapters. It is aimed at teaching students in courses where the full textbook is not needed, but the concepts included are desirable (such as graduate students in allied health programs or undergraduates). It is also aimed at students who are enrolled in courses that primarily use a traditional pathology textbook, but need the complementary concepts of molecular pathology (such as medical students). Further, the textbook will be valuable for pathology residents and other postdoctoral fellows who desire to advance their understanding of molecular mechanisms of disease beyond what they learned in medical/graduate school. Offers an essential introduction to molecular genetics and the "molecular" aspects of human disease Teaches from the perspective of "integrative systems biology," which encompasses the intersection of all molecular aspects of biology, as applied to understanding human disease In-depth presentation of the principles and practice of molecular pathology: molecular pathogenesis, molecular mechanisms of disease, and how the molecular pathogenesis of disease parallels the evolution of the disease using histopathology. "Traditional" pathology section provides state-of-the-art information on the major forms of disease, their pathologies, and the molecular mechanisms that drive these diseases. Explains the practice of "molecular medicine" and the translational aspects of molecular pathology: molecular diagnostics, molecular assessment, and personalized medicine Each chapter ends with Key Summary Points and Suggested Readings

The Right Therapy for Neurological Disorders

The Right Therapy for Neurological Disorders
Author: E. Beghi,G. Logroscino
Publsiher: Karger Medical and Scientific Publishers
Total Pages: 168
Release: 2016-07-26
ISBN 10: 3318058653
ISBN 13: 9783318058659
Language: EN, FR, DE, ES & NL

The Right Therapy for Neurological Disorders Book Review:

Most neurological disorders are chronic and aging-related. With the increase of life expectancy their incidence and prevalence will grow in the decades to come, which in turn will increase the load on medical and social systems worldwide. There is thus a desperate need for successful preventive and therapeutic measures based on randomized clinical trials (RTCs) conducted by independent organizations. This book provides a compendium relating most of the principles of reliable RTCs to specific neurological diseases. Contributed by specialized neurologists, the articles touch on important aspects of RCTs with a clear critical approach, highlighting their limitations as well as giving recommendations for their planning and conducting to address the variable genotypic and phenotypic aspects of neurological conditions. Consideration is also given to combining the clinical impact of the study results with patients’ values and the interests of pharmaceutical companies. Neurologists involved in clinical trials will certainly benefit from this book, which should become a basic text for all neurological courses dealing with evidence-based neurology.

Managing Chronic Conditions

Managing Chronic Conditions
Author: Ellen Nolte,Cécile Knai,Martin McKee
Publsiher: WHO Regional Office Europe
Total Pages: 181
Release: 2008
ISBN 10: 928904294X
ISBN 13: 9789289042949
Language: EN, FR, DE, ES & NL

Managing Chronic Conditions Book Review:

This book examines the health system response to the rising burden of chronic disease in eight countries. It provides a detailed assessment of the current situation, a description of the policy framework and future scenarios, as well as evaluation and lessons learned.