Translational Neuroimmunology in Multiple Sclerosis

Translational Neuroimmunology in Multiple Sclerosis
Author: Ruth Arnon,Ariel Miller
Publsiher: Academic Press
Total Pages: 502
Release: 2016-05-10
ISBN 10: 0128020075
ISBN 13: 9780128020074
Language: EN, FR, DE, ES & NL

Translational Neuroimmunology in Multiple Sclerosis Book Review:

Multiple sclerosis (MS) is the most common disabling neurological disease of young adults. More than 2.3 million people are affected by MS worldwide. Symptoms can vary widely, depending on the localization and amount of the damage induced by combined inflammatory, demyelinating, and neurodegenerative processes. Although a cure for MS does not currently exist, therapies can help treat MS attacks, attenuate disease activity, reduce progress of the disease, and manage symptoms. Translational Neuroimmunology in Multiple Sclerosis provides an overview of recent findings and knowledge of the neuroimmunology of multiple sclerosis, from experimental models and the human disease to the translation of this research to immunotherapeutic strategies. Chapters describe genetic and environmental factors underlying the disease pathogenesis of MS as a basis for development of immunotherapies, immunological markers of disease activity, pharmacogenetics, and responses to therapy. Immunomodulatory therapies currently in practice and future therapeutic strategies on the horizon—such as neuroprotective strategies, stem cells, and repair promotion—are discussed. Contributed by renowned leaders in the field, this cross-disciplinary volume is a great resource for basic scientists and clinical practitioners in neuroscience, neurology, immunology, pharmacology, and in-drug development. Provides an overview of recent findings and knowledge of the neuroimmunology of multiple sclerosis and the translation of this research to immunotherapy treatment Edited by renowned leaders in the field of neuroimmunology and multiple sclerosis Contains the latest resource material for basic and clinical scientists and practitioners in neuroscience, neurology, immunology, and pharmacology

Translational Neuroimmunology

Translational Neuroimmunology
Author: Nima Rezaei,Niloufar Yazdanpanah
Publsiher: Academic Press
Total Pages: 0
Release: 2023-03-23
ISBN 10: 9780443185786
ISBN 13: 0443185786
Language: EN, FR, DE, ES & NL

Translational Neuroimmunology Book Review:

Neuroimmunology is a growing field, which combines the knowledge of the immune system and the nervous system. Translational NeuroImmunology: Multiple Sclerosis as an Autoimmune Disease provides an update on bench to bedside studies on Multiple Sclerosis as an autoimmune disease. Divided into 12 chapters, the book begins with an in-depth introduction to the neuroimmunology and Immunopathology of multiple sclerosis. It also provides content on genetics and epigenetics, the microbiome, diagnosis and the treatment of multiple sclerosis is fully explained. Finally, the book various precision treatments of multiple sclerosis. All is presented in an accessible, practical format, making this volume a valuable resource for immunologists, neurologists, and researchers in translational biomedical research.

Update on Translational Neuroimmunology Research of ISNI 2018

Update on Translational Neuroimmunology   Research of ISNI 2018
Author: Sandra Amor,Fabienne Brilot,David Brown,Judith M. Greer,Marc J. Ruitenberg
Publsiher: Frontiers Media SA
Total Pages: 135
Release: 2020-12-29
ISBN 10: 2889662950
ISBN 13: 9782889662951
Language: EN, FR, DE, ES & NL

Update on Translational Neuroimmunology Research of ISNI 2018 Book Review:

The 14th International Congress of Neuroimmunology, ISNI 2018, was held in August 2018 in Brisbane, Australia, and is a biennial event organized by the International Society of Neuroimmunology (ISNI). The theme of ISNI 2018 was “Travelling the Neuroimmunological Translational Highway”, and the Congress highlighted many research discoveries that bridge the gap between basic and clinical sciences, and which impact our understanding of pathogenic immune-mediated mechanisms in diseases affecting the nervous system. In this Research Topic, we aim to give a comprehensive overview of topics highlighted at the Congress, showcasing the current state of the field of neuroimmunology and where it is going in the near future.

Translational Neuroimmunology

Translational Neuroimmunology
Author: Nima Rezaei
Publsiher: Academic Press
Total Pages: 0
Release: 2023-03-01
ISBN 10: 9780323858410
ISBN 13: 0323858414
Language: EN, FR, DE, ES & NL

Translational Neuroimmunology Book Review:

Neuroimmunology is a growing field, which combines the knowledge of the immune system and the nervous system. "Translational NeuroImmunology" addresses an update on bench to bedside studies on neurological disorders that have immunological aetiologies. Although neural-immune dysregulation and all autoimmune and autoinflammatory neurologic disorders will be discussed in this new volume of "Translational Immunology" Book Series. Divided into 22 chapters, the book begins with an in-depth introduction to neuroimmunology and the principles of autoimmune and autoinflammatory neurological disorders. Multiple sclerosis will be the main focus. The immunopathology, genetics and epigenetics, microbiome, diagnosis and treatment of multiple sclerosis will be explained in "Translational NeuroImmunology". 10 chapters are devoted to multiple sclerosis. The immunopathology, genetics and epigenetics, microbiome, diagnosis and treatment of multiple sclerosis will be explained. Following this, one chapter that examines distinct aspects of pericytes. Finally, the book closes with a review on the neurologic manifestations, diagnostic approaches and treatments of the various neuroimmune disorders and lessons learned from non-human primates and zebrafish translational research. All are presented in an accessible, practical format, making this volume a valuable resource for immunologists, neurologists and researchers in translational biomedical research.

Translational Methods for Multiple Sclerosis Research

Translational Methods for Multiple Sclerosis Research
Author: Sergiu Groppa,Sven G. Meuth
Publsiher: Humana
Total Pages: 335
Release: 2021-08-03
ISBN 10: 9781071612125
ISBN 13: 1071612123
Language: EN, FR, DE, ES & NL

Translational Methods for Multiple Sclerosis Research Book Review:

This volume explores the recent advances in the study of translational paths in central inflammation and focuses on ongoing pathophysiological processes and the transition between inflammatory stages and progressive states with neurodegeneration. Chapters cover topics such as pathophysiological hallmarks of neuroinflammation from tissue damage to reorganization; connecting studies of mouse models; and investigations of humans with multiple sclerosis. In the Neuromethods series style, chapters include the kind of detail and key advice from the specialists needed to get successful results in your laboratory. Cutting-edge and practical, Translational Methods for Multiple Sclerosis Research is a valuable resource for researchers who want to learn more about this chronic ad progressive disease, and pave the way for new advancements.

Conn s Translational Neuroscience

Conn s Translational Neuroscience
Author: P. Michael Conn
Publsiher: Academic Press
Total Pages: 776
Release: 2016-09-28
ISBN 10: 0128025964
ISBN 13: 9780128025963
Language: EN, FR, DE, ES & NL

Conn s Translational Neuroscience Book Review:

Conn’s Translational Neuroscience provides a comprehensive overview reflecting the depth and breadth of the field of translational neuroscience, with input from a distinguished panel of basic and clinical investigators. Progress has continued in understanding the brain at the molecular, anatomic, and physiological levels in the years following the 'Decade of the Brain,' with the results providing insight into the underlying basis of many neurological disease processes. This book alternates scientific and clinical chapters that explain the basic science underlying neurological processes and then relates that science to the understanding of neurological disorders and their treatment. Chapters cover disorders of the spinal cord, neuronal migration, the autonomic nervous system, the limbic system, ocular motility, and the basal ganglia, as well as demyelinating disorders, stroke, dementia and abnormalities of cognition, congenital chromosomal and genetic abnormalities, Parkinson's disease, nerve trauma, peripheral neuropathy, aphasias, sleep disorders, and myasthenia gravis. In addition to concise summaries of the most recent biochemical, physiological, anatomical, and behavioral advances, the chapters summarize current findings on neuronal gene expression and protein synthesis at the molecular level. Authoritative and comprehensive, Conn’s Translational Neuroscience provides a fully up-to-date and readily accessible guide to brain functions at the cellular and molecular level, as well as a clear demonstration of their emerging diagnostic and therapeutic importance. Provides a fully up-to-date and readily accessible guide to brain functions at the cellular and molecular level, while also clearly demonstrating their emerging diagnostic and therapeutic importance Features contributions from leading global basic and clinical investigators in the field Provides a great resource for researchers and practitioners interested in the basic science underlying neurological processes Relates and translates the current science to the understanding of neurological disorders and their treatment

Neuroinflammation

Neuroinflammation
Author: Alireza Minagar
Publsiher: Academic Press
Total Pages: 700
Release: 2018-07-30
ISBN 10: 0128117249
ISBN 13: 9780128117248
Language: EN, FR, DE, ES & NL

Neuroinflammation Book Review:

Neuroinflammation, Second Edition, discusses the role inflammation plays in neuro-inflammatory diseases. As research in neuroinflammation has dramatically increased in recent years, this new edition covers all of the new developments and findings since the first publication nearly a decade ago. Comprehensive coverage of topics includes chapters on multiple sclerosis, optic neuritis and Susac syndrome. New chapters cover the latest research in Epilepsy and Neuroinflammation, Pediatric MS, Pediatric Lupus and Traumatic Brain Injury, amongst other topics. Inflammation is a central mechanism in many neurological diseases, including stroke, multiple sclerosis, brain trauma and meningitis, and it contributes to the generation of pain. Researchers are now beginning to understand the impact of the immune system on different nervous system functions and diseases, ranging from damage, through tolerance, and to modulation and repair. Comprehensively reviews the latest developments in neuroinflammation and neuro-inflammatory diseases Written for researchers and clinical practitioners in clinical neuroscience, neurology and immunology Includes new chapters on Epilepsy and Neuroinflammation, Pediatric MS, Pediatric Lupus and Traumatic Brain Injury

Vitamin D

Vitamin D
Author: Öner Özdemir
Publsiher: BoD – Books on Demand
Total Pages: 196
Release: 2021-09-15
ISBN 10: 1839693495
ISBN 13: 9781839693496
Language: EN, FR, DE, ES & NL

Vitamin D Book Review:

This book examines the sometimes controversial role of vitamin D in various health problems. Divided into four sections, chapters cover such topics as vitamin D deficiency in women, newborns, and the elderly, as well as the role of vitamin D in COVID-19, autism spectrum disorder, diabetes, dental diseases, and central nervous system pathological processes.

Translational Inflammation

Translational Inflammation
Author: Anonim
Publsiher: Academic Press
Total Pages: 294
Release: 2018-11-24
ISBN 10: 0128138335
ISBN 13: 9780128138335
Language: EN, FR, DE, ES & NL

Translational Inflammation Book Review:

Translational Inflammation links laboratory and clinical data within primary and secondary care to clinical research data and offers a holistic and innovative approach to chronic inflammation and ageing. Understanding the role of inflammation as a part of clinical disease states is becoming a valuable tool in both direct treatment and the development of therapeutics. Translational Inflammation, the 4th volume in the Perspectives in Translational Cell Biology series, offers content for professors, students and researchers across basic and translational biology. Emphasizes the role of inflammation in disease and therapeutic approaches Integrates broad concepts relating inflammation to other fields Offers a bridge to review literature and primary research on the inflammatory response towards medical application

Machine Learning in Clinical Neuroimaging and Radiogenomics in Neuro oncology

Machine Learning in Clinical Neuroimaging and Radiogenomics in Neuro oncology
Author: Seyed Mostafa Kia,Hassan Mohy-ud-Din,Ahmed Abdulkadir,Cher Bass,Mohamad Habes,Jane Maryam Rondina,Chantal Tax,Hongzhi Wang,Thomas Wolfers,Saima Rathore,Madhura Ingalhalikar
Publsiher: Springer Nature
Total Pages: 305
Release: 2020-12-30
ISBN 10: 3030668436
ISBN 13: 9783030668433
Language: EN, FR, DE, ES & NL

Machine Learning in Clinical Neuroimaging and Radiogenomics in Neuro oncology Book Review:

This book constitutes the refereed proceedings of the Third International Workshop on Machine Learning in Clinical Neuroimaging, MLCN 2020, and the Second International Workshop on Radiogenomics in Neuro-oncology, RNO-AI 2020, held in conjunction with MICCAI 2020, in Lima, Peru, in October 2020.* For MLCN 2020, 18 papers out of 28 submissions were accepted for publication. The accepted papers present novel contributions in both developing new machine learning methods and applications of existing methods to solve challenging problems in clinical neuroimaging. For RNO-AI 2020, all 8 submissions were accepted for publication. They focus on addressing the problems of applying machine learning to large and multi-site clinical neuroimaging datasets. The workshop aimed to bring together experts in both machine learning and clinical neuroimaging to discuss and hopefully bridge the existing challenges of applied machine learning in clinical neuroscience. *The workshops were held virtually due to the COVID-19 pandemic.

Current Progress in iPSC Disease Modeling

Current Progress in iPSC Disease Modeling
Author: Alexander Birbrair
Publsiher: Academic Press
Total Pages: 324
Release: 2021-11-26
ISBN 10: 0323856438
ISBN 13: 9780323856430
Language: EN, FR, DE, ES & NL

Current Progress in iPSC Disease Modeling Book Review:

Current Progress in iPSC Disease Modeling, Volume Fourteen in the Advances in Stem Cell Biology series, is a timely and expansive collection of information and new discoveries in the field. This new volume addresses advances in research on how induced pluripotent stem cells are used for the creation of new tissues and organs. The creation of iPSC technology allowed the development of disease-specific human pluripotent stem cells. These cells allow researchers to study questions once impossible for some human diseases. This volume addresses iPSCs for vascular tissue engineering, bioprinting, derived lung organoids for pulmonary disorders, skeletal muscle engineering, human kidney organoids, and more. It is written for researchers and scientists in stem cell therapy, cell biology, regenerative medicine and organ transplantation, and is contributed by world-renowned authors in the field. Provides an overview of the fast-moving field of stem cell biology and function, regenerative medicine and therapeutics Covers advances in research on how induced pluripotent stem cells are used to create new tissues/organs Contributed by world-renowned experts in the field

Pathophysiologic Insights from Biomarker Studies in Neurological Disorders

Pathophysiologic Insights from Biomarker Studies in Neurological Disorders
Author: Tobias Ruck,Marcello Moccia,Tobias Warnecke,Stefan Bittner
Publsiher: Frontiers Media SA
Total Pages: 135
Release: 2020-04-01
ISBN 10: 2889636437
ISBN 13: 9782889636433
Language: EN, FR, DE, ES & NL

Pathophysiologic Insights from Biomarker Studies in Neurological Disorders Book Review:

Autoimmune Neurology

Autoimmune Neurology
Author: Anonim
Publsiher: Elsevier
Total Pages: 568
Release: 2016-03-11
ISBN 10: 0444634460
ISBN 13: 9780444634467
Language: EN, FR, DE, ES & NL

Autoimmune Neurology Book Review:

Autoimmune Neurology presents the latest information on autoimmune neurologic disease, the immune response to the body where organs run wild, causing the immune system to attack itself. Autoimmunity is a main element in numerous nervous system diseases and can target any structure within the central or peripheral nervous system. Over the past 20 years, significant advances in our understanding of the pathophysiology of autoimmune disorders, including the use of biomarkers has led to new diagnosis and treatment options. Neurologic conditions associated with autoimmune reactions include dementia, neuromuscular disease, epilepsy, sleep disorders, diabetes, and other common neurologic disorders and disease. This current tutorial-reference will be a must-have title for clinical neurologists, research neurologists, neuroscientists, and any medical professional working with autoimmune disease and disorders. Includes comprehensive coverage of autoimmune neurology Details the latest techniques for the study, diagnosis, and treatment of diseases and disorders, including dementia, neuromuscular disease, epilepsy, and sleep disorders Presents a focused reference for clinical practitioners and the clinical neurology and neurology research communities

A Primer of Neuroimmunological Disease

A Primer of Neuroimmunological Disease
Author: Andrew R. Pachner
Publsiher: Springer Science & Business Media
Total Pages: 208
Release: 2012-02-21
ISBN 10: 1461421888
ISBN 13: 9781461421887
Language: EN, FR, DE, ES & NL

A Primer of Neuroimmunological Disease Book Review:

A Primer of Neuroimmunological Disease is a significant new resource for anyone interested in conditions such as multiple sclerosis(MS), myasthenia gravis, and neurological infections. It is a practical and balanced guide to the diagnosis and treatment of neuroimmunological disease. A Primer of Neuroimmunological Disease distinguishes itself by providing a range of features not generally included in texts on neuroimmunology. These include broad presentation of information in the form of figures and tables; strong cohesion among topics by focusing on a few prototypic neuroimmunological diseases, which serve as a foundation from which to explore other neuroimmunological diseases; a single author perspective, with references across chapters; and a focus on the overlap between neuroimmunological and neuroinfectious diseases. Neurologists, immunologists, infectious disease specialists, neuroscientists and others interested in neuroimmunological diseases such as MS will find A Primer of Neuroimmunological to be a state-of-the-art resource.

Immunomodulators and Human Health

Immunomodulators and Human Health
Author: Rajesh K. Kesharwani,Raj K. Keservani,Anil K. Sharma
Publsiher: Springer Nature
Total Pages: 509
Release: 2022-06-17
ISBN 10: 9811663793
ISBN 13: 9789811663796
Language: EN, FR, DE, ES & NL

Immunomodulators and Human Health Book Review:

This book focuses on a broad range of immunomodulators, including both natural and synthetic ones. It highlights their role in human health. The book discusses nanotechnology-based immunomodulators with special emphasis on different types of formulation to boost the immune system. It highlights the role of immunomodulators against different microbes. This book describes important topics such as Classification and uses of various immunomodulators; Potential role of herbs and spices on immune system; Immune booster activity of prebiotics; Recent advances of nutraceutical and functional foods in Immune health; Antioxidants and immunomodulation; Nanotechnology and immunomodulators in cancer; Immunomodulatory role for the treatment and management of tuberculosis; Immunomodulation in autoimmune disorders; Herbal immunomodulators and COVID-19; Role of Cytokines as Immunomodulators and Immunomodulatory effects of endocrine disrupting chemicals. This book covers various aspects of product innovation, development, and launching of nutritional and pharmaceutical products with reference to immunomodulators. This book is meant for researchers and students in the field of immunology and pharmaceutical sciences.

FDA s Drug Review Process and the Package Label

FDA s Drug Review Process and the Package Label
Author: Tom Brody
Publsiher: Academic Press
Total Pages: 670
Release: 2017-12-13
ISBN 10: 0128146486
ISBN 13: 9780128146484
Language: EN, FR, DE, ES & NL

FDA s Drug Review Process and the Package Label Book Review:

FDA's Drug Review Process and the Package Label provides guidance to pharmaceutical companies for writing FDA-submissions, such as the NDA, BLA, Clinical Study Reports, and Investigator's Brochures. The book provides guidance to medical writers for drafting FDA-submissions in a way more likely to persuade FDA reviewers to grant approval of the drug. In detail, the book reproduces data on efficacy and safety from one hundred different FDA-submissions (NDAs, BLAs). The book reproduces comments and complaints from FDA reviewers regarding data that are fragmentary, ambiguous, or that detract from the drug's approvability, and the book reveals how sponsors overcame FDA's concerns and how sponsors succeeded in persuading FDA to grant approval of the drug. The book uses the most reliable and comprehensive source of information available for writing FDA-submissions, namely text and data from NDAs and BLAs, as published on FDA's website. The source material for writing this book included about 80,000 pages from FDA's Medical Reviews, FDA's Clinical Pharmacology Reviews, and FDA's Pharmacology Reviews, from one hundred different NDAs or BLAs for one hundred different drugs. Each chapter focuses on a different section of the package label, e.g., the Dosage and Administration section or the Drug Interactions section, and demonstrates how the sponsor's data supported that section of the package label. Reveals strategies for winning FDA approval and for drafting the package label Examples are from one hundred FDA-submissions (NDAs, BLAs) for one hundred different drugs, e.g., for oncology, metabolic diseases, autoimmune diseases, and neurological diseases This book uses the most reliable and comprehensive source of information available for writing FDA-submissions, namely, the data from NDAs and BLAs as published on FDA's website at the time FDA grants approval to the drug

Neuroimmune Diseases

Neuroimmune Diseases
Author: Hiroshi Mitoma,Mario Manto
Publsiher: Springer
Total Pages: 827
Release: 2019-08-13
ISBN 10: 3030195155
ISBN 13: 9783030195151
Language: EN, FR, DE, ES & NL

Neuroimmune Diseases Book Review:

A translational overview of neuroimmune diseases for neuroscientists and clinicians that clarifies the pathological mechanisms underlying neuroimmune diseases and builds a comprehensive bridge between the latest research findings and their clinical implications in daily practice. The material is presented in two steps. The first section comprises a review of the pathogenic actions of immune cells in brain diseases. Here the authors discuss the mechanisms through which immune cells disrupt the functions of nerve cells. The second section explores the ways in which the brain becomes dysfunctional due to impaired nerve cell function. Based on pathogenesis, diagnostic and therapeutic strategies are discussed for each clinical category. The book will be invaluable for use in clinical practice of neuroimmune diseases

Multiple Sclerosis

Multiple Sclerosis
Author: Carlos A. Perez,Andrew Smith,Flavia Nelson
Publsiher: Cambridge University Press
Total Pages: 288
Release: 2021-02-04
ISBN 10: 1108820751
ISBN 13: 9781108820752
Language: EN, FR, DE, ES & NL

Multiple Sclerosis Book Review:

Presents a practical and accessible approach to the diagnosis and management of multiple sclerosis in hospital and outpatient settings.

Recent Advances in Basic and Translational Osteoimmunology

Recent Advances in Basic and Translational Osteoimmunology
Author: Rupesh K. Srivastava,Naibedya Chattopadhyay,Katharina Schmidt-Bleek,Pradyumna Kumar Mishra,Massimo De Martinis
Publsiher: Frontiers Media SA
Total Pages: 135
Release: 2022-01-10
ISBN 10: 2889740145
ISBN 13: 9782889740147
Language: EN, FR, DE, ES & NL

Recent Advances in Basic and Translational Osteoimmunology Book Review:

Multiple Sclerosis From Bench to Bedside Currents Insights into Pathophysiological Concepts and Their Potential Impact on Patients

Multiple Sclerosis     From Bench to Bedside  Currents Insights into Pathophysiological Concepts and Their Potential Impact on Patients
Author: Paulus Stefan Rommer,Martin S. Weber,Zsolt Illes,Uwe K. Zettl
Publsiher: Frontiers Media SA
Total Pages: 135
Release: 2020-03-13
ISBN 10: 288963566X
ISBN 13: 9782889635665
Language: EN, FR, DE, ES & NL

Multiple Sclerosis From Bench to Bedside Currents Insights into Pathophysiological Concepts and Their Potential Impact on Patients Book Review: