Translational Biotechnology

Translational Biotechnology
Author: Yasha Hasija
Publsiher: Academic Press
Total Pages: 452
Release: 2021-01-17
ISBN 10: 0128219734
ISBN 13: 9780128219737
Language: EN, FR, DE, ES & NL

Translational Biotechnology Book Review:

Translational Biotechnology: A Journey from Laboratory to Clinics presents an integrative and multidisciplinary approach to biotechnology to help readers bridge the gaps between fundamental and functional research. The book provides state-of-the-art and integrative views of translational biotechnology by covering topics from basic concepts to novel methodologies. Topics discussed include biotechnology-based therapeutics, pathway and target discovery, biological therapeutic modalities, translational bioinformatics, and system and synthetic biology. Additional sections cover drug discovery, precision medicine and the socioeconomic impact of translational biotechnology. This book is valuable for bioinformaticians, biotechnologists, and members of the biomedical field who are interested in learning more about this promising field. Explains biotechnology in a different light by using an application-oriented approach Discusses practical approaches in the development of precision medicine tools, systems and dynamical medicine approaches Promotes research in the field of biotechnology that is translational in nature, cost-effective and readily available to the community

Translational Biotechnology

Translational Biotechnology
Author: Yasha Hasija
Publsiher: Academic Press
Total Pages: 452
Release: 2021-02-12
ISBN 10: 0128219726
ISBN 13: 9780128219720
Language: EN, FR, DE, ES & NL

Translational Biotechnology Book Review:

Translational Biotechnology: A Journey from Laboratory to Clinics presents an integrative and multidisciplinary approach to biotechnology to help readers bridge the gaps between fundamental and functional research. The book provides state-of-the-art and integrative views of translational biotechnology by covering topics from basic concepts to novel methodologies. Topics discussed include biotechnology-based therapeutics, pathway and target discovery, biological therapeutic modalities, translational bioinformatics, and system and synthetic biology. Additional sections cover drug discovery, precision medicine and the socioeconomic impact of translational biotechnology. This book is valuable for bioinformaticians, biotechnologists, and members of the biomedical field who are interested in learning more about this promising field. Explains biotechnology in a different light by using an application-oriented approach Discusses practical approaches in the development of precision medicine tools, systems and dynamical medicine approaches Promotes research in the field of biotechnology that is translational in nature, cost-effective and readily available to the community

Translational Bioinformatics in Healthcare and Medicine

Translational Bioinformatics in Healthcare and Medicine
Author: Anonim
Publsiher: Academic Press
Total Pages: 254
Release: 2021-05-13
ISBN 10: 0323898904
ISBN 13: 9780323898904
Language: EN, FR, DE, ES & NL

Translational Bioinformatics in Healthcare and Medicine Book Review:

Translational Bioinformatics in Healthcare and Medicine offers an overview of main principles of bioinformatics, biological databases, clinical informatics, health informatics, viroinformatics and real-case applications of translational bioinformatics in healthcare. Written by experts from both technology and clinical sides, the content brings together essential knowledge to make the best of recent advancements of the field. The book discusses topics such as next generation sequence analysis, genomics in clinical care, IoT applications, blockchain technology, patient centered interoperability of EHR, health data mining, and translational bioinformatics methods for drug discovery and drug repurposing. In addition, it discusses the role of bioinformatics in cancer research and viroinformatics approaches to counter viral diseases through informatics. This is a valuable resource for bioinformaticians, clinicians, healthcare professionals, graduate students and several members of biomedical field who are interested in learning more about how bioinformatics can impact in their research and practice. Covers recent advancements in translational bioinformatics and its healthcare applications Discusses integrative and multidisciplinary approaches to U-healthcare systems development and management Bridges the gap among various knowledge domains in the field, integrating both technological and clinical knowledge into practical content

Biotechnology Entrepreneurship

Biotechnology Entrepreneurship
Author: Craig Shimasaki
Publsiher: Academic Press
Total Pages: 682
Release: 2020-05-16
ISBN 10: 0128155868
ISBN 13: 9780128155868
Language: EN, FR, DE, ES & NL

Biotechnology Entrepreneurship Book Review:

This second edition of Biotechnology Entrepreneurship: Leading, Managing, and Commercializing Innovative Technologies is an authoritative, easy-to-read guide covering biotechnology entrepreneurship and the process of commercializing innovative biotechnology products. This best practice resource is for professional training programs, individuals starting a biotech venture, and for managers and experienced practitioners leading biotech enterprises. It is a valuable resource for those working at any level in the biotech industry, and for professionals who support and provide essential resources and services to the biotech industry. This practical, “how-to book is written by seasoned veterans experienced in each of the operational functions essential for starting, managing, and leading a successful biotech company. Biotechnology Entrepreneurship explains the biotech business components and underlying strategies, interspersed with practical lessons from successful biotech entrepreneurs, educators, and experienced practitioners. These veteran contributors share their insights on how to be successful in this challenging but exciting industry. Subjects range from technology licensing and translating an idea into a viable business, forming your legal company entity, securing angel and venture capital, navigating product development, FDA regulatory approval, and biomanufacturing. This book is a user-friendly guide to decision-making and overall strategy written as a hands-on management tool for leaders and managers of these dynamic biotechnology ventures. If you are contemplating starting a biotech company, are a manager at any level, a seasoned veteran, or service provider in the biotech industry, this book is a “must read. This second edition includes several new chapters on topics such as: What you need to know about valuation and term sheets Investor presentations and what you need in a biotech investor pitch deck Mentorship and why you need mentors Artificial intelligence applications in biotech and pharma Common biotech entrepreneur mistakes and how to avoid them

The Market in Mind

The Market in Mind
Author: Mark Dennis Robinson
Publsiher: MIT Press
Total Pages: 324
Release: 2019-07-23
ISBN 10: 0262536870
ISBN 13: 9780262536875
Language: EN, FR, DE, ES & NL

The Market in Mind Book Review:

A critical examination of translational medicine, when private risk is transferred to the public sector and university research teams become tech startups for global investors. A global shift has secretly transformed science and medicine. Starting in 2003, biomedical research in the West has been reshaped by the emergence of translational science and medicine—the idea that the aim of research is to translate findings as quickly as possible into medical products. In The Market in Mind, Mark Dennis Robinson charts this shift, arguing that the new research paradigm has turned university research teams into small biotechnology startups and their industry partners into early-stage investment firms. There is also a larger, surprising consequence from this shift: according to Robinson, translational science and medicine enable biopharmaceutical firms, as part of a broader financial strategy, to outsource the riskiest parts of research to nonprofit universities. Robinson examines the implications of this new configuration. What happens, for example, when universities absorb unknown levels of risk? Robinson argues that in the years since the global financial crisis translational science and medicine has brought about “the financialization of health.” Robinson explores such topics as shareholder anxiety and industry retreat from Alzheimer's and depression research; how laboratory research is understood as health innovation even when there is no product; the emergence of investor networking events as crucial for viewing science in a market context; and the place of patients in research decisions. Although translational medicine justifies itself by the goal of relieving patients' suffering, Robinson finds patients' voices largely marginalized in translational neuroscience.

Clinical and Translational Science

Clinical and Translational Science
Author: David Robertson,Gordon H. Williams
Publsiher: Academic Press
Total Pages: 808
Release: 2016-11-25
ISBN 10: 012802111X
ISBN 13: 9780128021118
Language: EN, FR, DE, ES & NL

Clinical and Translational Science Book Review:

Clinical and Translational Science: Principles of Human Research, Second Edition, is the most authoritative and timely resource for the broad range of investigators taking on the challenge of clinical and translational science, a field that is devoted to investigating human health and disease, interventions, and outcomes for the purposes of developing new treatment approaches, devices, and modalities to improve health. This updated second edition has been prepared with an international perspective, beginning with fundamental principles, experimental design, epidemiology, traditional and new biostatistical approaches, and investigative tools. It presents complete instruction and guidance from fundamental principles, approaches, and infrastructure, especially for human genetics and genomics, human pharmacology, research in special populations, the societal context of human research, and the future of human research. The book moves on to discuss legal, social, and ethical issues, and concludes with a discussion of future prospects, providing readers with a comprehensive view of this rapidly developing area of science. Introduces novel physiological and therapeutic strategies for engaging the fastest growing scientific field in both the private sector and academic medicine Brings insights from international leaders into the discipline of clinical and translational science Addresses drug discovery, drug repurposing and development, innovative and improved approaches to go/no-go decisions in drug development, and traditional and innovative clinical trial designs

Handbook of translational medicine

Handbook of translational medicine
Author: Josep M. Llovet
Publsiher: Edicions Universitat Barcelona
Total Pages: 244
Release: 2016-10-05
ISBN 10: 8447540308
ISBN 13: 9788447540303
Language: EN, FR, DE, ES & NL

Handbook of translational medicine Book Review:

This handbook aims to capture the basic concepts of translational medicine, understood as a branch of the biomedical field that translates discoveries into the clinical setting. This discipline is currently closing the gap between basic science and clinical research. The book is intended to be straightforward, easy-to-read, intelligible and practical. It describes the basic principles of translational medicine, including major advances in genomics, new technologies, the processing of big data and biobanks. Regarding the biological foundations of translational medicine, we address concepts related to the molecular basis of cancer, inflammation, angiogenesis, stem cells and experimental models. More specifically on translational medicine, we present discoveries and breakthroughs in oncology, neuroscience, metabolic and systemic diseases, and public health. Finally, we have specific sections focused on clinical trials and biomarkers in the genomic era, advances in imaging techniques and entrepreneurship and innovation. Our purpose is to offer a manageable text to guide graduate and post-graduate students, professionals and researchers in biomedicine through the major technologies and advances that have occurred in the translational field. It is also intended to aid residents, fellows and physician-scientists working in hospitals and academic institutions.

Principles of Translational Science in Medicine

Principles of Translational Science in Medicine
Author: Martin Wehling
Publsiher: Academic Press
Total Pages: 494
Release: 2021-07-15
ISBN 10: 032399962X
ISBN 13: 9780323999625
Language: EN, FR, DE, ES & NL

Principles of Translational Science in Medicine Book Review:

Principles of Translational Science in Medicine: From Bench to Bedside, Third Edition, provides an update on major achievements in the translation of research into medically relevant results and therapeutics. The book presents a thorough discussion of biomarkers, early human trials, and networking models, and includes institutional and industrial support systems. It also covers algorithms that have influenced all major areas of biomedical research in recent years, resulting in an increasing number of new chemical/biological entities (NCEs or NBEs) as shown in FDA statistics. New chapters include: Translation in Oncology, Biologicals, and Orphan Drugs. The book is ideal for use as a guide for biomedical scientists to establish a systematic approach to translational medicine and is written by worldwide experts in their respective fields. Includes state-of-the-art principles, tools such as biomarkers and early clinical trials, algorithms of translational science in medicine Provides in-depth description of special translational aspects in the currently most successful areas of clinical translation, namely oncology and immunology Covers status of institutionalization of translational medicine, networking structures and outcomes at the level of marketing authorization

Animal Biotechnology

Animal Biotechnology
Author: Ashish S. Verma,Anchal Singh
Publsiher: Academic Press
Total Pages: 798
Release: 2020-07-03
ISBN 10: 0128117109
ISBN 13: 9780128117101
Language: EN, FR, DE, ES & NL

Animal Biotechnology Book Review:

Animal Biotechnology: Models in Discovery and Translation, Second Edition, provides a helpful guide to anyone seeking a thorough review of animal biotechnology and its application to human disease and welfare. This updated edition covers vital fundamentals, including animal cell cultures, genome sequencing analysis, epigenetics and animal models, gene expression, and ethics and safety concerns, along with in-depth examples of implications for human health and prospects for the future. New chapters cover animal biotechnology as applied to various disease types and research areas, including in vitro fertilization, human embryonic stem cell research, biosensors, enteric diseases, biopharming, organ transplantation, tuberculosis, neurodegenerative disorders, and more. Highlights the latest biomedical applications of genetically modified and cloned animals, with a focus on cancer and infectious diseases Offers first-hand accounts of the use of biotechnology tools, including molecular markers, stem cells, animal cultures, tissue engineering, ADME and CAM Assay Includes case studies that illustrate safety assessment issues, ethical considerations, and intellectual property rights associated with the translation of animal biotechnology studies

Advances in Bioartificial Materials and Tissue Engineering Research and Application 2012 Edition

Advances in Bioartificial Materials and Tissue Engineering Research and Application  2012 Edition
Author: Anonim
Publsiher: ScholarlyEditions
Total Pages: 827
Release: 2012-12-26
ISBN 10: 1464991464
ISBN 13: 9781464991462
Language: EN, FR, DE, ES & NL

Advances in Bioartificial Materials and Tissue Engineering Research and Application 2012 Edition Book Review:

Advances in Bioartificial Materials and Tissue Engineering Research and Application / 2012 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Bioartificial Materials and Tissue Engi. The editors have built Advances in Bioartificial Materials and Tissue Engineering Research and Application / 2012 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Bioartificial Materials and Tissue Engi in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Advances in Bioartificial Materials and Tissue Engineering Research and Application / 2012 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

De Novo Peptide Design

De Novo Peptide Design
Author: Vibin Ramakrishnan,Kirti Patel,Ruchika Goyal
Publsiher: Academic Press
Total Pages: 297
Release: 2022-09-30
ISBN 10: 0323985432
ISBN 13: 9780323985437
Language: EN, FR, DE, ES & NL

De Novo Peptide Design Book Review:

De novo Peptide Design: Principles and Applications presents the latest developments in the fields of therapeutic peptides and bio-nanotechnology. The title focuses on the design of peptides, particularly how peptides may be tailored to specific functions. It includes computational and experimental protocols to assist in the design of peptides. Sections cover the basics of protein and peptide structure, modeling and simulation, solid phase peptide synthesis, peptide-based antibiotics, drug delivery, peptide nanomaterials, aromatic interactions directing nano-assembly, protein/peptide aggregation, therapeutic interventions against protein/peptide aggregation diseases, peptide based hydrogels, computational tools and algorithms for peptide design, and experimental protocols in peptide chemistry. In addition, the book covers key aspects in peptide design, providing a solution for researchers working within the 'peptidic universe' to create new therapeutic agents. Gives comprehensive coverage, including peptide design, modeling, synthesis and applications Presents emerging topics in the design of peptide-based therapeutics Details the latest developments in the fields of therapeutic peptides and bio-nanotechnology Considers peptide design and the tailoring of peptides to specific functions Offers computational tools and algorithms for peptide design and experimental protocols for peptide chemistry

Human Microbiome in Health and Disease Part A

Human Microbiome in Health and Disease   Part A
Author: Anonim
Publsiher: Elsevier
Total Pages: 290
Release: 2022-10-01
ISBN 10: 0323997872
ISBN 13: 9780323997874
Language: EN, FR, DE, ES & NL

Human Microbiome in Health and Disease Part A Book Review:

Human Microbiome in Health and Disease, Volume 191, Part A presents updated knowledge on human microbiome as covered by renowned science faculty across the globe. Chapters in this volume include an introduction to human microbiome, Structure, functions and diversity of healthy human microbiome, Role of human microbiome in cancer, Gut microbiota and gastrointestinal cancer, Dysbiosis of human microbiome and metabolic diseases, Gut microbiome and type 2 diabetes, Gut microbiome and non-alcoholic fatty liver disease, Hepatic drug metabolism and intestinal microbiota, Emerging tools for understanding the human microbiome, and Microbiome therapeutics: Opportunity and challenges, and more. These chapters cover the composition, diversity, dynamics and functions of human microbiome in health and disease. This book will form an excellent and informative text on keystone, autochthonous, and exogenous microbiota important for human health in a simple to understand and easy to read format. Covers the structure, functions and diversity of human microbiome in health and disease Includes discussions on drug metabolisms and microbiome based therapeutics Presents emerging tools for understanding the human microbiome

Translational Toxicology

Translational Toxicology
Author: Claude L. Hughes,Michael D. Waters
Publsiher: Humana Press
Total Pages: 380
Release: 2016-03-23
ISBN 10: 331927449X
ISBN 13: 9783319274492
Language: EN, FR, DE, ES & NL

Translational Toxicology Book Review:

Bringing together a distinguished interdisciplinary team of contributors, this volume provides a comprehensive exploration of translational toxicology—a systematic approach to developing therapeutic interventions that can protect against, mitigate, or reverse the effects of exposures. In particular, the book addresses modes of action and biomarkers, developmental risks of exposures, and potential translational toxicology therapeutics. The result is a compelling application of developmental toxicology in a new therapeutic discipline that is destined to become part of standard medical practice. Translational Toxicology: Defining a New Therapeutic Discipline is an essential text for regulatory authorities, scientists, and physicians who are concerned with environmental exposures, public health, nutrition, and pharmaceutical research and development. Basic science, epidemiological, and clinical investigators will also find this book a significant resource.

Translational Regenerative Medicine

Translational Regenerative Medicine
Author: Anthony Atala,Julie Allickson
Publsiher: Academic Press
Total Pages: 606
Release: 2014-12-01
ISBN 10: 0124104576
ISBN 13: 9780124104570
Language: EN, FR, DE, ES & NL

Translational Regenerative Medicine Book Review:

Translational Regenerative Medicine is a reference book that outlines the life cycle for effective implementation of discoveries in the dynamic field of regenerative medicine. By addressing science, technology, development, regulatory, manufacturing, intellectual property, investment, financial, and clinical aspects of the field, this work takes a holistic look at the translation of science and disseminates knowledge for practical use of regenerative medicine tools, therapeutics, and diagnostics. Incorporating contributions from leaders in the fields of translational science across academia, industry, and government, this book establishes a more fluid transition for rapid translation of research to enhance human health and well-being. Provides formulaic coverage of the landscape, process development, manufacturing, challenges, evaluation, and regulatory aspects of the most promising regenerative medicine clinical applications Covers clinical aspects of regenerative medicine related to skin, cartilage, tendons, ligaments, joints, bone, fat, muscle, vascular system, hematopoietic /immune system, peripheral nerve, central nervous system, endocrine system, ophthalmic system, auditory system, oral system, respiratory system, cardiac system, renal system, hepatic system, gastrointestinal system, genitourinary system Identifies effective, proven tools and metrics to identify and pursue clinical and commercial regenerative medicine

Comprehensive Biotechnology

Comprehensive Biotechnology
Author: Anonim
Publsiher: Elsevier
Total Pages: 4870
Release: 2019-07-17
ISBN 10: 0444640479
ISBN 13: 9780444640475
Language: EN, FR, DE, ES & NL

Comprehensive Biotechnology Book Review:

Comprehensive Biotechnology, Third Edition unifies, in a single source, a huge amount of information in this growing field. The book covers scientific fundamentals, along with engineering considerations and applications in industry, agriculture, medicine, the environment and socio-economics, including the related government regulatory overviews. This new edition builds on the solid basis provided by previous editions, incorporating all recent advances in the field since the second edition was published in 2011. Offers researchers a one-stop shop for information on the subject of biotechnology Provides in-depth treatment of relevant topics from recognized authorities, including the contributions of a Nobel laureate Presents the perspective of researchers in different fields, such as biochemistry, agriculture, engineering, biomedicine and environmental science

Animal Biotechnology

Animal Biotechnology
Author: Ashish S. Verma,Anchal Singh
Publsiher: Academic Press
Total Pages: 798
Release: 2020-06-11
ISBN 10: 0128117257
ISBN 13: 9780128117255
Language: EN, FR, DE, ES & NL

Animal Biotechnology Book Review:

Animal Biotechnology: Models in Discovery and Translation, Second Edition, provides a helpful guide to anyone seeking a thorough review of animal biotechnology and its application to human disease and welfare. This updated edition covers vital fundamentals, including animal cell cultures, genome sequencing analysis, epigenetics and animal models, gene expression, and ethics and safety concerns, along with in-depth examples of implications for human health and prospects for the future. New chapters cover animal biotechnology as applied to various disease types and research areas, including in vitro fertilization, human embryonic stem cell research, biosensors, enteric diseases, biopharming, organ transplantation, tuberculosis, neurodegenerative disorders, and more. Highlights the latest biomedical applications of genetically modified and cloned animals, with a focus on cancer and infectious diseases Offers first-hand accounts of the use of biotechnology tools, including molecular markers, stem cells, animal cultures, tissue engineering, ADME and CAM Assay Includes case studies that illustrate safety assessment issues, ethical considerations, and intellectual property rights associated with the translation of animal biotechnology studies

Budget Volume for

Budget Volume for
Author: India
Publsiher: Unknown
Total Pages: 1890
Release: 2011
ISBN 10: 1928374650XXX
ISBN 13: UCBK:C106476628
Language: EN, FR, DE, ES & NL

Budget Volume for Book Review:

Bound set of budget documents (central budget and railway budget), 23 or more numbered issues; most of the the titles are also published separately.

Botanical Drug Products

Botanical Drug Products
Author: Jayant N. Lokhande,Yashwant V. Pathak
Publsiher: CRC Press
Total Pages: 274
Release: 2018-11-21
ISBN 10: 1498740065
ISBN 13: 9781498740067
Language: EN, FR, DE, ES & NL

Botanical Drug Products Book Review:

Botanicals, which have been part of human food and medicine for thousands of years, are perceived as being safer than synthetic pharmaceuticals. The global botanical drug market was expected to reach $26.6 billion by 2017. In terms of FDA regulations, botanical drugs are no different from non-botanical products, having to meet the safety and effectiveness standards of a new drug in accordance. This book comprises a complete start-to-end process from drug-idea conception, to drug development process. Key Features: Provides a complete compendium for botanical drug products Describes what BDP is and how it differs from Pharma, Biopharma, and Nutraceuticals Compiles all critical regulatory steps in a variety of countries Discusses clinical trial management for BDP development and how it differs from conventional chemical-based drugs and biopharmaceutics

Science Technology and Innovation in BRICS Countries

Science  Technology and Innovation in BRICS Countries
Author: Swapan Kumar Patra,Mammo Muchie
Publsiher: Routledge
Total Pages: 154
Release: 2020-06-30
ISBN 10: 1000049302
ISBN 13: 9781000049305
Language: EN, FR, DE, ES & NL

Science Technology and Innovation in BRICS Countries Book Review:

The term BRICS (Brazil, Russia, India, China and South Africa) is gaining global attention both in scholarly and popular discourse. BRICS countries are crucial in terms of their vast areas, huge population and have massive economic potential. These countries are also categorized as developing countries and are aspiring to be considered as developed countries. There is commonality among these countries in that they have similar issues and problems, which may require common solutions. Science, Technology and Innovation in BRICS Countries examines whether more emphasis on Science Technology and Innovation (STI) capability building could be the solution to these countries’ economic upgradation and poverty reduction. This book is a collection of various Science Technology and Innovation (STI) issues of BRICS economics, and will be of interest to general readers, scholars working in this field, as well as policy makers all over the globe. The contributions come from various scholars across the globe who have published their BRICS economics research in a special issue of the African Journal of Science, Technology, Innovation and Development.

Neuronal and Synaptic Dysfunction in Autism Spectrum Disorder and Intellectual Disability

Neuronal and Synaptic Dysfunction in Autism Spectrum Disorder and Intellectual Disability
Author: Carlo Sala,Chiara Verpelli
Publsiher: Academic Press
Total Pages: 394
Release: 2016-04-30
ISBN 10: 0128005335
ISBN 13: 9780128005330
Language: EN, FR, DE, ES & NL

Neuronal and Synaptic Dysfunction in Autism Spectrum Disorder and Intellectual Disability Book Review:

Neuronal and Synaptic Dysfunction in Autism Spectrum Disorder and Intellectual Disability provides the latest information on Autism spectrum disorders (ASDs), the lifelong neurodevelopmental disorders that present in early childhood and affect how individuals communicate and relate to others and their surroundings. In addition, three quarters of ASD patients also manifest severe intellectual disability. Though certain genes have been implicated, ASDs remain largely a mystery, and research looking into causes and cellular deficits are crucial for better understanding of neurodevelopmental disorders. Despite the prevalence and insidious nature of this disorder, this book remains to be an extensive resource of information and background on the state of current research in the field. The book serves as a reference for this purpose, and discusses the crucial role synaptic activity plays in proper brain function. In addition, the volume discusses the neurodevelopmental synaptopathies and serves as a resource for scientists and clinicians in all biomedical science specialties. This research has been crucial for recent studies that have provided a rationale for the development of pharmacological agents able to counteract functional synaptic anomalies and potentially ameliorate some ASD symptoms. Introduces the genetic and non-genetic causes of autism and associated intellectual disabilities Describes the genes implicated in autistic spectrum disorders and their function Considers major individual genetic causes of autism, Rett syndrome, Fragile X syndrome, and other autism spectrum disorders, as well as their classification as synaptopathies Presents a thorough discussion of the clinical aspects of multiple neurodevelopmental disorders and the experimental models that exist to study their pathophysiology in vitro and in vivo, including animal models and patient-derived stem cell culture