TDP 43 and Neurodegeneration

TDP 43 and Neurodegeneration
Author: Vijay Kumar,Manoj Kumar Jaiswal
Publsiher: Academic Press
Total Pages: 270
Release: 2021-10-23
ISBN 10: 0128204400
ISBN 13: 9780128204405
Language: EN, FR, DE, ES & NL

TDP 43 and Neurodegeneration Book Review:

Aggregates of the TAR DNA binding protein 43 (TDP-43), are hallmark features of the neurodegenerative diseases Amyotrophic Lateral Sclerosis (ALS) and frontotemporal dementia (FTD), with overlapping clinical, genetic and pathological features. TDP-43 and Neurodegeneration: From Bench to Bedside summarizes new findings in TDP-43 pathobiology and proteinopathies. The book summarizes TDP-43’s structure, function, biology, misfolding, aggregation, pathogenesis and therapeutics. It includes autophagy-mediated therapy, role of stress granule, novel genetic, cell culture-based models, systems biology for precision medicine, development of stem cells and mechanism-based therapies that can target ALS and other related neurodegenerative diseases. This book is written for neuroscientists, neurologists, clinicians, advanced graduate students, drug discovery researchers, as well as cellular and molecular biologists involved in ALS, motor neuron disease (MND) and other neurodegenerative disorders. Reviews TDP-43 structure, folding, function, and pathology Identifies TDP-43 role in ALS, FTP, and other neurodegenerative diseases Presents a systems and precision biology perspective of TDP-43 Discusses therapeutics of TDP-43 proteinopathies Translates bench research to application bedside

Advanced Understanding of Neurodegenerative Diseases

Advanced Understanding of Neurodegenerative Diseases
Author: Raymond Chuen-Chung Chang
Publsiher: BoD – Books on Demand
Total Pages: 456
Release: 2011-12-16
ISBN 10: 9533075295
ISBN 13: 9789533075297
Language: EN, FR, DE, ES & NL

Advanced Understanding of Neurodegenerative Diseases Book Review:

Advanced Understanding of Neurodegenerative Diseases focuses on different types of diseases, including Alzheimer's disease, frontotemporal dementia, different tauopathies, Parkinson's disease, prion disease, motor neuron diseases such as multiple sclerosis and spinal muscular atrophy. This book provides a clear explanation of different neurodegenerative diseases with new concepts of understand the etiology, pathological mechanisms, drug screening methodology and new therapeutic interventions. Other chapters discuss how hormones and health food supplements affect disease progression of neurodegenerative diseases. From a more technical point of view, some chapters deal with the aggregation of prion proteins in prion diseases. An additional chapter to discuss application of stem cells. This book is suitable for different readers: college students can use it as a textbook; researchers in academic institutions and pharmaceutical companies can take it as updated research information; health care professionals can take it as a reference book, even patients' families, relatives and friends can take it as a good basis to understand neurodegenerative diseases.

Stem Cell Therapy for Organ Failure

Stem Cell Therapy for Organ Failure
Author: Indumathi Somasundaram
Publsiher: Springer
Total Pages: 278
Release: 2015-01-02
ISBN 10: 8132221109
ISBN 13: 9788132221104
Language: EN, FR, DE, ES & NL

Stem Cell Therapy for Organ Failure Book Review:

The book “STEM CELL THERAPY FOR ORGAN FAILURES” edited by Dr. S. Indumathi demonstrates the In Vitro and In vivo therapeutic strategies and applications of pre- and post-natal stem cells for treating the failures of various organ systems of our body in a wide perspective. It explores the past, present and the futuristic approach of the exciting field of stem cells and its intriguing properties involved in tissue repair and regeneration. The prime focus of this volume is to unravel the basic, advanced, therapeutic and translational approaches put-forth so far in the field of stem cells and regenerative medicine at research, pre-clinical and clinical levels. Stem cells has ushered in widespread interest and exciting possibilities for cell based therapies, albeit failures do prevail and small uncontrolled phase I/II studies are only signals generating, rather than definite proof of concept thereby limiting its applicability in curative therapeutics. Despite certain initiatives and meticulous untiring efforts, bringing this basic bench side research into advanced transitional bedside remained a challenge. Thus, this book embarked upon the expanding researches in these areas that seem decisive in improvising regenerative medical therapeutics, thereby leading to further path-breaking studies that cure all health challenges facing mankind. Overall, this book reveals the imperativeness of various stem cell sources and its utility in curative therapeutics.

Geriatric Neurology

Geriatric Neurology
Author: Anonim
Publsiher: Elsevier
Total Pages: 616
Release: 2019-12-18
ISBN 10: 0128051418
ISBN 13: 9780128051412
Language: EN, FR, DE, ES & NL

Geriatric Neurology Book Review:

Geriatric Neurology, Volume 167, serves as an update on the basic biological and behavioral mechanisms underlying the aging process, with an emphasis on neurological aging and state-of-the-art reviews on our understanding of vascular, cognitive, neurodegenerative and neuropsychiatric diseases in the elderly. Developed with an eye to providing both the basic underpinnings of age-related changes and the clinical information necessary to aid in diagnostics and treatment, the book serves as a useful volume for students, basic and translational scientists, and practicing clinicians on how to understand and treat common neurological disorders in the elderly. Reviews the foundations of geriatric neurology, including the fundamentals of age associated changes in molecular biology, altered pharmacokinetics and psychopharmacology that make drug therapy in the elderly different from younger patients Contains major advances in our understanding of neurodegenerative diseases Features contributions from world leaders in geriatric neurology–the broadest, most expert coverage available

Pathobiology of Human Disease

Pathobiology of Human Disease
Author: Anonim
Publsiher: Elsevier
Total Pages: 5000
Release: 2014-08-01
ISBN 10: 0123864577
ISBN 13: 9780123864574
Language: EN, FR, DE, ES & NL

Pathobiology of Human Disease Book Review:

Pathobiology of Human Disease bridges traditional morphologic and clinical pathology, molecular pathology, and the underlying basic science fields of cell biology, genetics, and molecular biology, which have opened up a new era of research in pathology and underlie the molecular basis of human disease. The work spans more than 48 different biological and medical fields, in five basic sections: Human Organ Systems Molecular Pathology/Basic Mechanisms of Diseases Animal Models/Other Model Systems Experimental Pathology Clinical Pathology Each article provides a comprehensive overview of the selected topic to inform a broad spectrum of readers from research professionals to advanced undergraduate students. Reviews quantitative advances in the imaging and molecular analysis of human tissue, new microarray technologies for analysis of genetic and chromosomal alterations in normal and diseased cells and tissues, and new transgenic models of human disease using conditional, tissue-specific gene targeting Articles link through to relevant virtual microscopy slides, illustrating side-by-side presentation of "Normal" and "Disease" anatomy and histology images Fully-annotated with many supplementary full color images, graphs, tables, and video files linked to data sets and to live references, enabling researchers to delve deeper and visualize solutions

RNA Metabolism in Neurodegenerative Diseases

RNA Metabolism in Neurodegenerative Diseases
Author: Rita Sattler,Christopher J. Donnelly
Publsiher: Springer
Total Pages: 310
Release: 2018-06-18
ISBN 10: 331989689X
ISBN 13: 9783319896892
Language: EN, FR, DE, ES & NL

RNA Metabolism in Neurodegenerative Diseases Book Review:

It has become evident over the last years that abnormalities in RNA processing play a fundamental part in the pathogenesis of neurodegenerative diseases. Cellular viability depends on proper regulation of RNA metabolism and subsequent protein synthesis, which requires the interplay of many processes including transcription, pre--‐mRNA splicing, mRNA editing as well as mRNA stability, transport and translation. Dysfunction in any of these processes, often caused by mutations in the coding and non--‐ coding RNAs, can be very destructive to the cellular environment and consequently impair neural viability. The result of this RNA toxicity can lead to a toxic gain of function or a loss of function, depending on the nature of the mutation. For example, in repeat expansion disorders, such as the newly discovered hexanucleotide repeat expansion in theC9orf72 gene found in amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD), a toxic gain of function leads to the formation of RNA foci and the sequestration of RNA binding proteins (RBPs). This in return leads to a loss of function of those RBPs, which is hypothesized to play a significant part in the disease progression of ALS and FTD. Other toxicities arising from repeat expansions are the formation of RNA foci, bi--‐directional transcription and production of repeat associated non--‐ATG (RAN) translation products. This book will touch upon most of these disease mechanisms triggered by aberrant RNA metabolism and will therefore provide a broad perspective of the role of RNA processing and its dysfunction in a variety of neurodegenerative disorders, including ALS, FTD, Alzheimer’s disease, Huntington’s disease, spinal muscular atrophy, myotonic dystrophy and ataxias. The proposed authors are leading scientists in the field and are expected to not only discuss their own work, but to be inclusive of historic as well as late breaking discoveries. The compiled chapters will therefore provide a unique collection of novel studies and hypotheses aimed to describe the consequences of altered RNA processing events and its newest molecular players and pathways.

Spectrums of Amyotrophic Lateral Sclerosis

Spectrums of Amyotrophic Lateral Sclerosis
Author: Christopher A. Shaw,Jessia R. Morrice
Publsiher: John Wiley & Sons
Total Pages: 240
Release: 2021-05-04
ISBN 10: 1119745519
ISBN 13: 9781119745518
Language: EN, FR, DE, ES & NL

Spectrums of Amyotrophic Lateral Sclerosis Book Review:

SPECTRUMS OF AMYOTROPHIC LATERAL SCLEROSIS Discover state-of-the-art research findings on ALS from leading authors and editors in the field In Spectrums of Amyotrophic Lateral Sclerosis: Heterogeneity, Pathogenesis & Therapeutic Directions, distinguished researchers and editors Dr. Christopher A. Shaw and Jessica R. Morrice deliver a practical and powerful perspective on Amyotrophic Lateral Sclerosis (ALS) as a heterogeneous spectrum of disorders. This increasingly accepted point-of-view allows researchers and medical professionals to develop better targeted interventions and more precise therapies. In the book, readers will find chapters on a wide variety of critical issues facing ALS researchers and healthcare practitioners treating ALS sufferers, including animal models of ALS, neuronal support cells known to have a pivotal role in ALS, and current challenges in ALS clinical trials, among others. The authors describe pathologic features common to all cases of ALS and why animal models, though crucial, should be interpreted with caution. Finally, multiple genetic and environmental etiologies of the disease are discussed. Readers will also benefit from the inclusion of: A thorough introduction to ALS as a spectrum disease and the implications for models, therapeutic development and clinical trial design Explorations of the genetic basis of ALS, prospective sALS etiologies, and the involvement of microbiome in ALS Discussions of ALS-PDC and environmental risk factors, protein aggregation in ALS, defects in RNA metabolism in ALS, and the non-cell autonomous nature of ALS and the involvement of glial cells Examinations of animal models of ALS and perspectives on previously failed ALS therapeutics and current therapeutic strategies Perfect for clinical neurologists, healthcare providers and caretakers, clinicians, and researchers studying motor neuron disease, Spectrums of Amyotrophic Lateral Sclerosis: Heterogeneity, Pathogenesis & Therapeutic Directions is also an indispensable resource for the neurodegenerative research community, neurology residents, and graduate-level neuroscience students.

Neuroprotection in Alzheimer s Disease

Neuroprotection in Alzheimer s Disease
Author: Illana Gozes
Publsiher: Academic Press
Total Pages: 342
Release: 2016-12-30
ISBN 10: 0128037121
ISBN 13: 9780128037126
Language: EN, FR, DE, ES & NL

Neuroprotection in Alzheimer s Disease Book Review:

Neuroprotection in Alzheimer’s Disease offers a translational point-of-view from both basic and clinical standpoints, putting it on the cusp for further clinical development with its emphasis on nerve cell protection, including the accumulation of knowledge from failed clinical trials and new advances in disease management. This book brings together the latest findings, both basic, and clinical, under the same cover, making it easy for the reader to obtain a complete overview of the state-of-the-field and beyond. Alzheimer's disease is the most common form of dementia, accounting for 60 to 80 percent of dementia cases. It is a progressive brain disease that slowly destroys memory, thinking skills, and eventually, even the ability to carry out the simplest tasks. It is characterized by death of synapses coupled to death nerve cells and brain degeneration which is manifested by loss of cognitive abilities. Understanding neuroprotection in Alzheimer’s disease will pave the path to better disease management and novel therapeutics. Comprehensive reference detailing neuroprotection in Alzheimer’s Disease, with details on nerve cell protection and new advances in disease management Combines the knowledge and points-of-view of both medical doctors and basic scientists, putting the subject at the forefront for further clinical development Edited by one of the leading researchers in Alzheimer’s Disease

Personalised Medicine

Personalised Medicine
Author: Sherif El-Khamisy
Publsiher: Springer
Total Pages: 260
Release: 2017-08-24
ISBN 10: 3319607332
ISBN 13: 9783319607337
Language: EN, FR, DE, ES & NL

Personalised Medicine Book Review:

The mammalian genome is constantly challenged by exogenous and endogenous threats. Although much is known about the mechanisms that maintain genome integrity, little is known about the applications of this knowledge to combat human disease. The past 20 years has witnessed extensive research and progress in this area and scientists started to design new therapies harnessing individual genetic differences among patients to combat degenerative disorders and cancer. We summarize these advancements and discuss perspectives for the future of personalized medicine.

Tau oligomers

Tau oligomers
Author: Jesus Avila,Naruhiko Sahara
Publsiher: Frontiers E-books
Total Pages: 135
Release: 2014-08-18
ISBN 10: 288919261X
ISBN 13: 9782889192618
Language: EN, FR, DE, ES & NL

Tau oligomers Book Review:

Neurofibrillary tangles (NFTs) composed of intracellular aggregates of tau protein are a key neuropathological feature of Alzheimer’s Disease (AD) and other neurodegenerative diseases, collectively termed tauopathies. The abundance of NFTs has been reported to correlate positively with the severity of cognitive impairment in AD. However, accumulating evidences derived from studies of experimental models have identified that NFTs themselves may not be neurotoxic. Now, many of tau researchers are seeking a “toxic” form of tau protein. Moreover, it was suggested that a “toxic” tau was capable to seed aggregation of native tau protein and to propagate in a prion-like manner. However, the exact neurotoxic tau species remain unclear. Because mature tangles seem to be non-toxic component, “tau oligomers” as the candidate of “toxic” tau have been investigated for more than one decade. In this topic, we will discuss our consensus of “tau oligomers” because the term of “tau oligomers” [e.g. dimer (disulfide bond-dependent or independent), multimer (more than dimer), granular (definition by EM or AFM) and maybe small filamentous aggregates] has been used by each researchers definition. From a biochemical point of view, tau protein has several unique characteristics such as natively unfolded conformation, thermo-stability, acid-stability, and capability of post-translational modifications. Although tau protein research has been continued for a long time, we are still missing the mechanisms of NFT formation. It is unclear how the conversion is occurred from natively unfolded protein to abnormally mis-folded protein. It remains unknown how tau protein can be formed filaments [e.g. paired helical filament (PHF), straight filament and twisted filament] in cells albeit in vitro studies confirmed tau self-assembly by several inducing factors. Researchers are still debating whether tau oligomerization is primary event rather than tau phosphorylation in the tau pathogenesis. Inhibition of either tau phosphorylation or aggregation has been investigated for the prevention of tauopathies, however, it will make an irrelevant result if we don’t know an exact target of neurotoxicity. It is a time to have a consensus of definition, terminology and methodology for the identification of “tau oligomers”.

Mechanisms of Secondary Brain Damage

Mechanisms of Secondary Brain Damage
Author: A. Baethmann,K. G. Go,A. Unterberg
Publsiher: Springer Science & Business Media
Total Pages: 406
Release: 2013-03-09
ISBN 10: 1468452037
ISBN 13: 9781468452037
Language: EN, FR, DE, ES & NL

Mechanisms of Secondary Brain Damage Book Review:

A distinction between primary and secondary brain damage of vari ous origin, particularly in acute lesions, such as head injury and ische mia is not entirely new. The concept is of practical significance, be cause it is the foremost intention of all clinical efforts to prevent, or at least attenuate the development of secondary sequelae. Primary dam age to nervous elements usually cannot be influenced by treatment. Its prevention is the objective of prophylactic measures. The current volume gathered prominent scientists and clinicians from various fields to pro vide a competent introduction and survey of the various aspects involved in secondary brain damage. It was attempted to provide criteria for the distinction between the primary and secondary phenomena on a morpho logical and functional level, on the basis of the kinetics involved and, most importantly, regarding the different specific manifestations, such as disturbances of microcirculation, aspects of the blood-brain barrier, and of cellular structure and function at a molecular level. Although it was not expected that a grand unifying hypothesis will be reached recon cilable with the many, occasionally opposing views on such a complex subject, nevertheless, the present volume attains an appropriate result. It can best be described as a mosaic of many different pieces which only as an ensemble reflect the current state of the art.

Brain Transcriptome

Brain Transcriptome
Author: Anonim
Publsiher: Academic Press
Total Pages: 358
Release: 2014-08-27
ISBN 10: 0128013192
ISBN 13: 9780128013199
Language: EN, FR, DE, ES & NL

Brain Transcriptome Book Review:

Published since 1959, International Review of Neurobiology is a well-known series appealing to neuroscientists, clinicians, psychologists, physiologists, and pharmacologists. Led by an internationally renowned editorial board, this important serial publishes both eclectic volumes made up of timely reviews and thematic volumes that focus on recent progress in a specific area of neurobiology research. This volume, concentrates on the brain transcriptome. Brings together cutting-edge research on the brain transcriptome

Cerebral Microcirculation

Cerebral Microcirculation
Author: Frithjof Hammersen,K. Messmer
Publsiher: S Karger Ag
Total Pages: 102
Release: 1990
ISBN 10: 1928374650XXX
ISBN 13: UOM:39015017752976
Language: EN, FR, DE, ES & NL

Cerebral Microcirculation Book Review:

Human and Animal Models for Translational Research on Neurodegeneration Challenges and Opportunities From South America

Human and Animal Models for Translational Research on Neurodegeneration  Challenges and Opportunities From South America
Author: Agustín Ibáñez,Lucas Sedeño,Adolfo M. García,Robert M.J. Deacon,Patricia Cogram
Publsiher: Frontiers Media SA
Total Pages: 135
Release: 2018-06-21
ISBN 10: 2889454940
ISBN 13: 9782889454945
Language: EN, FR, DE, ES & NL

Human and Animal Models for Translational Research on Neurodegeneration Challenges and Opportunities From South America Book Review:

Neurodegenerative diseases are the most frequent cause of dementia, representing a burden for public health systems (especially in middle and middle-high income countries). Although most research on this issue is concentrated in first-world centers, growing efforts in South America are affording important breakthroughs. This emerging agenda poses new challenges for the region but also new opportunities for the field. This book aims to integrate the community of experts across the globe and the region, and to establish new challenges and developments for future investigation. We present research focused on neurodegenerative research in South America. We introduce studies assessing the interplay among genetic, neural, and behavioral dimensions of these diseases, as well as articles on vulnerability factors, comparisons of findings from various countries, and works promoting multicenter and collaborative networking. More generally, our book covers a broad scope of human-research approaches (behavioral assessment, neuroimaging, electromagnetic techniques, brain connectivity, peripheral measures), animal methodologies (genetics, epigenetics, proteomics, metabolomics, other molecular biology tools), species (all human and non-human animals, sporadic, and genetic versions), and article types (original research, review, and opinion papers). Through this wide-ranging proposal, we hope to introduce a fresh approach to the challenges and opportunities of research on neurodegeneration in South America.

Magnesium in the Central Nervous System

Magnesium in the Central Nervous System
Author: Robert Vink,Mihai Nechifor
Publsiher: University of Adelaide Press
Total Pages: 342
Release: 2011
ISBN 10: 0987073052
ISBN 13: 9780987073051
Language: EN, FR, DE, ES & NL

Magnesium in the Central Nervous System Book Review:

The brain is the most complex organ in our body. Indeed, it is perhaps the most complex structure we have ever encountered in nature. Both structurally and functionally, there are many peculiarities that differentiate the brain from all other organs. The brain is our connection to the world around us and by governing nervous system and higher function, any disturbance induces severe neurological and psychiatric disorders that can have a devastating effect on quality of life. Our understanding of the physiology and biochemistry of the brain has improved dramatically in the last two decades. In particular, the critical role of cations, including magnesium, has become evident, even if incompletely understood at a mechanistic level. The exact role and regulation of magnesium, in particular, remains elusive, largely because intracellular levels are so difficult to routinely quantify. Nonetheless, the importance of magnesium to normal central nervous system activity is self-evident given the complicated homeostatic mechanisms that maintain the concentration of this cation within strict limits essential for normal physiology and metabolism. There is also considerable accumulating evidence to suggest alterations to some brain functions in both normal and pathological conditions may be linked to alterations in local magnesium concentration. This book, containing chapters written by some of the foremost experts in the field of magnesium research, brings together the latest in experimental and clinical magnesium research as it relates to the central nervous system. It offers a complete and updated view of magnesiums involvement in central nervous system function and in so doing, brings together two main pillars of contemporary neuroscience research, namely providing an explanation for the molecular mechanisms involved in brain function, and emphasizing the connections between the molecular changes and behavior. It is the untiring efforts of those magnesium researchers who have dedicated their lives to unraveling the mysteries of magnesiums role in biological systems that has inspired the collation of this volume of work.

Pathology Prevention and Therapeutics of Neurodegenerative Disease

Pathology  Prevention and Therapeutics of Neurodegenerative Disease
Author: Sarika Singh,Neeraj Joshi
Publsiher: Springer
Total Pages: 301
Release: 2018-09-24
ISBN 10: 9811309442
ISBN 13: 9789811309441
Language: EN, FR, DE, ES & NL

Pathology Prevention and Therapeutics of Neurodegenerative Disease Book Review:

This book, written by a leading panel of experts in the field of neurosciences, provides a comprehensive overview of the pathology of neurodegenerative diseases as well as the preventive measures. Prevention is important due to the lack of early diagnostic markers and the limitations/ problems of treating neurodegenerative diseases

Mitochondrial Function

Mitochondrial Function
Author: Anonim
Publsiher: Academic Press
Total Pages: 506
Release: 2014-11-10
ISBN 10: 0128016159
ISBN 13: 9780128016152
Language: EN, FR, DE, ES & NL

Mitochondrial Function Book Review:

This new volume of Methods in Enzymology continues the legacy of this premier serial with quality chapters authored by leaders in the field. Methods to assess mitochondrial function is of great interest to neuroscientists studying chronic forms of neurodegeneration, including Parkinson's, Alzheimer's, ALS, Huntington's and other triplet repeat diseases, but also to those working on acute conditions such as stroke and traumatic brain injury. This volume covers research methods on how to assess the life cycle of mitochondria including trafficking, fusion, fission, and degradation. Multiple perspectives on the complex and difficult problem of measurement of mitochondrial reactive oxygen species production with fluorescent indicators and techniques ranging in scope from measurements on isolated mitochondria to non-invasive imaging of metabolic function. Continues the legacy of this premier serial with quality chapters authored by leaders in the field Covers research methods in biomineralization science Provides invaluable details on state-of-the-art methods to assess a broad array of mitochondrial functions

Myopathology

Myopathology
Author: Balan Louis Gaspar,Rakesh Kumar Vasishta,Bishan Dass Radotra
Publsiher: Springer
Total Pages: 299
Release: 2018-09-24
ISBN 10: 9811314624
ISBN 13: 9789811314629
Language: EN, FR, DE, ES & NL

Myopathology Book Review:

This book covers all aspects of basic, essential, recent advances and controversies in myopathology. The major emphasis is on diagnostic myopathology of muscular dystrophies, inflammatory myopathies, mitochondrial myopathies, metabolic myopathies, congenital myopathies, myopathies of miscellaneous etiology, neurogenic and neuromuscular junction disorders, the goal being to broaden readers’ understanding of individual disease subgroups. The book also contains all the essential details needed to establish a neuromuscular lab, making it especially relevant for laboratory technical staff and research scholars.

Brain Neurotrauma

Brain Neurotrauma
Author: Firas H. Kobeissy
Publsiher: CRC Press
Total Pages: 725
Release: 2015-02-25
ISBN 10: 1466565993
ISBN 13: 9781466565999
Language: EN, FR, DE, ES & NL

Brain Neurotrauma Book Review:

Every year, an estimated 1.7 million Americans sustain brain injury. Long-term disabilities impact nearly half of moderate brain injury survivors and nearly 50,000 of these cases result in death. Brain Neurotrauma: Molecular, Neuropsychological, and Rehabilitation Aspects provides a comprehensive and up-to-date account on the latest developments in the area of neurotrauma, including brain injury pathophysiology, biomarker research, experimental models of CNS injury, diagnostic methods, and neurotherapeutic interventions as well as neurorehabilitation strategies in the field of neurotraum research. The book includes several sections on neurotrauma mechanisms, biomarker discovery, neurocognitive/neurobehavioral deficits, and neurorehabilitation and treatment approaches. It also contains a section devoted to models of mild CNS injury, including blast and sport-related injuries. Over the last decade, the field of neurotrauma has witnessed significant advances, especially at the molecular, cellular, and behavioral levels. This progress is largely due to the introduction of novel techniques, as well as the development of new animal models of central nervous system (CNS) injury. This book, with its diverse coherent content, gives you insight into the diverse and heterogeneous aspects of CNS pathology and/or rehabilitation needs.

Nutrition and Traumatic Brain Injury

Nutrition and Traumatic Brain Injury
Author: Institute of Medicine,Food and Nutrition Board,Committee on Nutrition, Trauma, and the Brain
Publsiher: National Academies Press
Total Pages: 444
Release: 2011-07-01
ISBN 10: 0309210089
ISBN 13: 9780309210089
Language: EN, FR, DE, ES & NL

Nutrition and Traumatic Brain Injury Book Review:

Traumatic brain injury (TBI) accounts for up to one-third of combat-related injuries in Iraq and Afghanistan, according to some estimates. TBI is also a major problem among civilians, especially those who engage in certain sports. At the request of the Department of Defense, the IOM examined the potential role of nutrition in the treatment of and resilience against TBI.