Synaptic Transmission

Synaptic Transmission
Author: Stephen D. Meriney,Erika Fanselow
Publsiher: Academic Press
Total Pages: 528
Release: 2019-06-12
ISBN 10: 0128153210
ISBN 13: 9780128153215
Language: EN, FR, DE, ES & NL

Synaptic Transmission Book Review:

Synaptic Transmission is a comprehensive guide to the topic of neurotransmission that provides an in-depth discussion on many aspects of synapse structure and function—a fundamental part of the neuroscience discipline. Chapters include boxes that describe renowned/award-winning researchers and their contributions to the field of synaptic transmission, diseases relevant to the material presented, details of experimental approaches used to study synaptic transmission, and interesting asides that expand on topics covered. This book will inspire students to appreciate how the basic cellular and molecular biology of the synapse can lead to a better understanding of nervous system function and neurological disorders. Provides a comprehensive reference on synaptic structure, physiology, function and neurotransmission Discusses many landmark experiments in the field of synaptic transmission to emphasize core principles Includes references to primary scientific literature, relevant review articles and books, many of which could be assigned as discussion material for courses focused on this topic

Synaptic Transmission and Long term Potentiation at the Mossy Fiber Synapse of the Hippocampus

Synaptic Transmission and Long term Potentiation at the Mossy Fiber Synapse of the Hippocampus
Author: Marc Gabriel Weisskopf
Publsiher: Unknown
Total Pages: 378
Release: 1995
ISBN 10: 1928374650XXX
ISBN 13: UCAL:X58572
Language: EN, FR, DE, ES & NL

Synaptic Transmission and Long term Potentiation at the Mossy Fiber Synapse of the Hippocampus Book Review:

The Synapse

The Synapse
Author: Virginia M. Pickel,Menahem Segal
Publsiher: Elsevier
Total Pages: 512
Release: 2013-11-16
ISBN 10: 0124186823
ISBN 13: 9780124186828
Language: EN, FR, DE, ES & NL

The Synapse Book Review:

The Synapse summarizes recent advances in cellular and molecular mechanisms of synaptic transmission and provides new insights into neuronal plasticity and the cellular basis of neurological diseases. Part 1 provides an in-depth look at structural differences and distribution of various pre- and post-synaptic proteins found at glutamatergic synapses. Part 2 is dedicated to dendritic spines and their associated perisynaptic glia, which together constitute the tripartite synapse. The spines are portrayed as major sites for calcium sequestration and local protein synthesis. Part 3 highlights the important regional and cellular differences between glutamatergic transmission and that of neurotransmitters such as dopamine and acetylcholine that are commonly found in axon terminals without synaptic membrane specializations. Part 4 provides an overview of the synapse from the time of formation to degeneration under the powerful influence of aging or hormonal decline that leads to severe deficits in cognitive function. Each chapter is illustrated with drawings and images derived from calcium imaging, electron microscopic immunolabeling, or electrophysiology. This book is a valuable reference for neuroscientists and clinical neurologists in both research and clinical settings. A comprehensive reference focused on the structure and function of the synapse Covers the links between the synapse and neural plasticity and the cellular basis of neurologic disease Detailed coverage of dendritic spines and associated perisynaptic glia—the tripartite synapse Includes in-depth coverage of synapse degeneration due to aging or hormonal decline related to severe cognitive impairment

Aspects of Synaptic Transmission

Aspects of Synaptic Transmission
Author: T. W. Stone
Publsiher: Taylor & Francis
Total Pages: 404
Release: 1991
ISBN 10: 9780850668285
ISBN 13: 085066828X
Language: EN, FR, DE, ES & NL

Aspects of Synaptic Transmission Book Review:

A collection of reviews on selected areas of synaptic transmission from neuroscientists in a number of areas of work in the nervous system and related disciplines. Five areas are covered - long-term potentiation, galanin, autonomic, opioids and 5-hydroxytryptamine.

Neurotransmitter Release

Neurotransmitter Release
Author: Hugo J. Bellen
Publsiher: Oxford University Press, USA
Total Pages: 437
Release: 1999
ISBN 10: 1928374650XXX
ISBN 13: UOM:39015048547338
Language: EN, FR, DE, ES & NL

Neurotransmitter Release Book Review:

Begins by providing a comprehensive introduction to the features and properties of synapses. It then describes key techniques used to study neurotransmitter release, from calcium entry to exocytosis. This is followed by chapters covering the identification and function of proteins involved in neurotransmitter release, the role of phospholipids in neurosecretion, and neurotransmitter transporter proteins. Subsequent chapters concentrate on approaches to unravel the function of specific proteins in vivo using toxins that affect neurotransmitter release, giant squit axons, C. elegans, Drosophila, and mice.

The Molecular Mechanism Behind Synaptic Transmission

The Molecular Mechanism Behind Synaptic Transmission
Author: Jiajie Diao,Cong Ma
Publsiher: Frontiers Media SA
Total Pages: 135
Release: 2020-05-05
ISBN 10: 2889636925
ISBN 13: 9782889636921
Language: EN, FR, DE, ES & NL

The Molecular Mechanism Behind Synaptic Transmission Book Review:

Mechanisms of Synaptic Transmission

Mechanisms of Synaptic Transmission
Author: Anonim
Publsiher: Elsevier
Total Pages: 360
Release: 1969
ISBN 10: 9780080861562
ISBN 13: 0080861563
Language: EN, FR, DE, ES & NL

Mechanisms of Synaptic Transmission Book Review:

Mechanisms of Synaptic Transmission

Mechanisms of Synaptic Transmission

Mechanisms of Synaptic Transmission
Author: Joseph D. Robinson
Publsiher: Oxford University Press
Total Pages: 472
Release: 2001-05-17
ISBN 10: 0198031459
ISBN 13: 9780198031451
Language: EN, FR, DE, ES & NL

Mechanisms of Synaptic Transmission Book Review:

Synaptic transmission plays a central role in the nervous system as the mechanism that allows for chemical and electrical communication between cells and thus connects discrete elements into the functioning whole. This is a broad account of anatomical, biochemical, embryological, medical, pathological, pharmacological, and physiological studies on synaptic transmission during the hundred years beginning in 1890. During this century, the process of synaptic transmission came to be recognized not only as the most fundamental neurophysiological process, but also as a seat of pathological changes, and as the predominant site of action for drugs used to treat a wide range of psychiatric and neurological disorders. At the same time, research from these various disciplines was transformed into a new and unifying field, neuroscience. The course of these investigations reveals ingenious experiments, powerful new techniques, and imaginative insights. The author describes broadly who did what, when, where, and how (and, in cases where it is apparent, why) and uses experimental results and interpretations to display the evolutionary course to our current understanding of how nerve cells communicate: the basic principle of neural functioning. The book will be of interest to basic and clinical neuroscientists, pharmacologists, and physiologists, to historians and philosophers of the life sciences and medicine, and to their respective students.

Dynamics and Modulation of Synaptic Transmission in the Mammalian CNS

Dynamics and Modulation of Synaptic Transmission in the Mammalian CNS
Author: Maria Elisa Calcagnotto,Alberto A. Rasia-Filho,Idan Segev
Publsiher: Frontiers Media SA
Total Pages: 135
Release: 2019-06-21
ISBN 10: 2889458911
ISBN 13: 9782889458912
Language: EN, FR, DE, ES & NL

Dynamics and Modulation of Synaptic Transmission in the Mammalian CNS Book Review:

Stress and Steroid regulation of synaptic transmission from physiology to pathophysiology

Stress and Steroid regulation of synaptic transmission  from physiology to pathophysiology
Author: Menahem Segal,Harmen J. Krugers,Nicola Maggio
Publsiher: Frontiers E-books
Total Pages: 135
Release: 2022
ISBN 10: 9782889191031
ISBN 13: 2889191036
Language: EN, FR, DE, ES & NL

Stress and Steroid regulation of synaptic transmission from physiology to pathophysiology Book Review:

Recently, several pioneering discoveries have identified new roles of stress and steroid hormones in modulating CNS functions. Specifically, glucocorticoids, mineralocorticoids, sex hormones and neurosteroids have been shown to affect synaptic receptors and ion channels and therefore regulate in a complex manner physiological processes ranging from homeostatic to cognitive functions. Likewise, in some disorders of the nervous system, steroid hormones have been shown to play different roles: either favoring or combating the disease process. In this Frontier Research Topic, we have put together leaders in the field to provide novel opinions on the effects of steroid hormones on synaptic transmission and plasticity from ion channels to pathophysiological processes. We expect critical reviews of the work that has been conducted recently in this area and enrich these discussions with the novel, exciting new findings.

Central Cholinergic Synaptic Transmission

Central Cholinergic Synaptic Transmission
Author: Frotscher,Misgeld
Publsiher: Birkhäuser
Total Pages: 324
Release: 2013-03-07
ISBN 10: 3034891385
ISBN 13: 9783034891387
Language: EN, FR, DE, ES & NL

Central Cholinergic Synaptic Transmission Book Review:

Our knowledge of cholinergic synaptic transmission in the peripheral nervous system (PNS) has expanded enormously since the early 1930's, at which time O. Loewi discovered chemical neurotransmission through acetylcholine (ACh) and the pharmacological actions of ACh were described by H. Dale and his colleagues. Description of ACh's actions and receptors in various parts of the brain was followed by a detailed analysis of ACh's synthesis, release mechanism, removal from the synaptic cleft, modes of agonist-receptor interactions, properties of regulated conductances and of the pre-and postsynaptic modulation of cholinergic synapses. Our knowledge has been increasingly consolidat ing, leading us to the recent clarification of the structure of the periph eral nicotinic receptor-ion channel and its functional properties. It is appropriate to maintain the claim that the fundamentals of our under standing of synaptic transmission come from studies on cholinergic synapses in the PNS. Contrastingly, views held on the role of cholinergic synapses in the mammalian central nervous system (CNS) are extremely controversial, although it has been clear for some time that ACh is present in the brain. Illustrating this, no unanimous view is held on the role of nicotinic receptors in the CNS. There is one notable exception to this confusion: Studies begun by J. C. Eccles and associates in the 1960's and completed by D. R. Curtis and R. W.

Cellular and Molecular Basis of Synaptic Transmission

Cellular and Molecular Basis of Synaptic Transmission
Author: Herbert Zimmermann
Publsiher: Springer Science & Business Media
Total Pages: 547
Release: 2013-06-29
ISBN 10: 3642731724
ISBN 13: 9783642731723
Language: EN, FR, DE, ES & NL

Cellular and Molecular Basis of Synaptic Transmission Book Review:

Major progresses in the study of the cellular and molecular basis of synaptic transmission of nerve cells are highlighted. Each individual contribution gives an overview of the subject, presenting a description of the technical approach and considering future perspectives of the developments in the field. Topics range from historical aspects of the development of biochemical studies on synaptic transmission to the most advanced techniques applicable in morphological and functional studies of the nerve terminal. Studies on synaptic vesicles, the regulation of presynaptic transmitter synthesis, transmitter-release and especially the molecular structure and function of presynaptic ion channels and of transmitter receptors offer a detailed insight into synaptic events.

Modulation of Synaptic Transmission and Plasticity in Nervous Systems

Modulation of Synaptic Transmission and Plasticity in Nervous Systems
Author: Georg Hertting,Hanns-Christof Spatz
Publsiher: Springer Science & Business Media
Total Pages: 457
Release: 2013-06-29
ISBN 10: 3642731600
ISBN 13: 9783642731600
Language: EN, FR, DE, ES & NL

Modulation of Synaptic Transmission and Plasticity in Nervous Systems Book Review:

This volume is based on a workshop "Modulation of Synaptic Transmission and Plasticity in Nervous Systems" held in n Ciocco, Castelvecchio, Pascoli, Italy, from September 8th to 13th, 1987. The purpose of the meeting was to bring together scientists working on plasticity in nervous systems on different levels. The contributions can be subgrouped into six fields of research: 1) Presynaptic Modulation of Chemical Neurotransmission 2) Postsynaptic Signal Transduction 3) Modulation of Synaptic Transmission and Plasticity in the Hippocampus 4) Modulation of Neuromuscular Transmission 5) Molecular and Cellular Analysis of Conditioning in Marine Snails 6) Analysis of Learning and Memory in Insects Understanding how nervous systems and in particular our brain processes and stores information has been a major challenge in science for centuries and will remain for some time to come. Not until recently neurobiologists agreed to seek plasticity of behavior primarily in the modulation of the properties of synapses between nerve cells. This is to be understood within the context provided by a neural circuitry. An important stimulus came from the work on the marine snail Aplysia, where learning processes can be described as a modulation of transmitter release, traced back to a complete chain of molecular events in an identified neuron. Learning became a topic of molecular biology. Three systems appear particularly promising for this approach: insects, in particular Drosophila, marine snails and the mammalian hippocampal tissue. Our views on neurotransmission have rapidly changed.

Electrophysiological Analysis of Synaptic Transmission

Electrophysiological Analysis of Synaptic Transmission
Author: Nicholas Graziane,Yan Dong
Publsiher: Unknown
Total Pages: 263
Release: 2016
ISBN 10: 9781493932740
ISBN 13: 1493932748
Language: EN, FR, DE, ES & NL

Electrophysiological Analysis of Synaptic Transmission Book Review:

Electrophysiology is one of the finest approaches capable of detecting and analyzing electrical events in the brain. However, like all other experimental approaches, it has its limitations. This book was created to serve as a guide for those endeavoring to understand the function of electrophysiology and its underlying components: neurons, neural systems, and the brain. It introduces and highlights important topics in the field of electrophysiology, while also extending these topics to practical electrophysiological approaches through the perspective of the two authors. This book is ideal for graduate students or junior postdoctoral fellows interested in starting a journey in synaptic neuroscience.

Drugs and Central Synaptic Transmission

Drugs and Central Synaptic Transmission
Author: Anonim
Publsiher: Macmillan International Higher Education
Total Pages: 391
Release: 1976-06-18
ISBN 10: 1349012475
ISBN 13: 9781349012473
Language: EN, FR, DE, ES & NL

Drugs and Central Synaptic Transmission Book Review:

Protein Dynamics and Membrane Traffic in Synaptic Transmission and Synaptic Plasticity

Protein Dynamics and Membrane Traffic in Synaptic Transmission and Synaptic Plasticity
Author: Cong Ma,Zhitao Hu,Wei Liu
Publsiher: Frontiers Media SA
Total Pages: 135
Release: 2022-02-14
ISBN 10: 2889743659
ISBN 13: 9782889743650
Language: EN, FR, DE, ES & NL

Protein Dynamics and Membrane Traffic in Synaptic Transmission and Synaptic Plasticity Book Review:

Introduction to Cellular Biophysics Volume 2

Introduction to Cellular Biophysics  Volume 2
Author: Armin Kargol
Publsiher: Morgan & Claypool Publishers
Total Pages: 106
Release: 2019-12-13
ISBN 10: 1643277561
ISBN 13: 9781643277561
Language: EN, FR, DE, ES & NL

Introduction to Cellular Biophysics Volume 2 Book Review:

All living matter is comprised of cells, small compartments isolated from the environment by a cell membrane and filled with concentrated solutions of various organic and inorganic compounds. Some organisms are single-cell, where all life functions are performed by that cell. Others have groups of cells, or organs, specializing in one particular function. The survival of the entire organism depends on all of its cells and organs fulfilling their roles. While the cells are studied by different sciences, they are seen differently by biologists, chemists, or physicists. Biologists concentrate their attention on cell structure and function. What the cells consists of? Where are its organelles? What function each organelle fulfils? From a chemists’ point of view, a cell is a complex chemical reaction chamber where various molecules are synthesized or degraded. The main question is how these, sometimes very complicated chains of reactions are controlled. Finally, from a physics standpoint, some of the fundamental questions are about the physical movement of all these molecules between organelles within the cell, their exchange with the extracellular medium, as well as electrical phenomena resulting from such transport. The aim of this book is to look into the basic physical phenomena occurring in cells. These physical transport processes facilitate chemical reactions in the cell and various electrical effects, and that in turn leads to biological functions necessary for the cell to satisfy its role in the mother organism. Ultimately, the goals of every cell are to stay alive and to fulfill its function as a part of a larger organ or organism. The first volume of this book is an inventory of physical transport processes occurring in cells while this second volume provides a closer look at how complex biological and physiological cell phenomena result from these very basic physical processes.

Glutamate Related Biomarkers in Drug Development for Disorders of the Nervous System

Glutamate Related Biomarkers in Drug Development for Disorders of the Nervous System
Author: Institute of Medicine,Board on Health Sciences Policy,Forum on Neuroscience and Nervous System Disorders
Publsiher: National Academies Press
Total Pages: 74
Release: 2011-07-05
ISBN 10: 0309212243
ISBN 13: 9780309212243
Language: EN, FR, DE, ES & NL

Glutamate Related Biomarkers in Drug Development for Disorders of the Nervous System Book Review:

Glutamate is the most pervasive neurotransmitter in the central nervous system (CNS). Despite this fact, no validated biological markers, or biomarkers, currently exist for measuring glutamate pathology in CNS disorders or injuries. Glutamate dysfunction has been associated with an extensive range of nervous system diseases and disorders. Problems with how the neurotransmitter glutamate functions in the brain have been linked to a wide variety of disorders, including schizophrenia, Alzheimer's, substance abuse, and traumatic brain injury. These conditions are widespread, affecting a large portion of the United States population, and remain difficult to treat. Efforts to understand, treat, and prevent glutamate-related disorders can be aided by the identification of valid biomarkers. The Institute of Medicine's Forum on Neuroscience and Nervous System Disorders held a workshop on June 21-22, 2010, to explore ways to accelerate the development, validation, and implementation of such biomarkers. Glutamate-Related Biomarkers in Drug Development for Disorders of the Nervous System: Workshop Summary investigates promising current and emerging technologies, and outlines strategies to procure resources and tools to advance drug development for associated nervous system disorders. Moreover, this report highlights presentations by expert panelists, and the open panel discussions that occurred during the workshop.

Jasper s Basic Mechanisms of the Epilepsies

Jasper s Basic Mechanisms of the Epilepsies
Author: Jeffrey Noebels,Massimo Avoli,Michael Rogawski,Richard Olsen,Antonio Delgado-Escueta
Publsiher: Oxford University Press
Total Pages: 1264
Release: 2012-06-01
ISBN 10: 0199842590
ISBN 13: 9780199842599
Language: EN, FR, DE, ES & NL

Jasper s Basic Mechanisms of the Epilepsies Book Review:

H.H. Jasper, A.A. Ward, A. Pope and H.H. Merritt, chair of the Public Health Service Advisory Committee on the Epilepsies, National Institutes of Health, published the first volume on Basic Mechanisms of the Epilepsies (BME) in 1969. Their ultimate goal was to search for a "better understanding of the epilepsies and seek more rational methods of their prevention and treatment." Since then, basic and clinical researchers in epilepsy have gathered together every decade and a half with these goals in mind -- assessing where epilepsy research has been, what it has accomplished, and where it should go. In 1999, the third volume of BME was named in honor of H.H. Jasper. In line with the enormous expansion in the understanding of basic epilepsy mechanisms over the past four decades, this fourth edition of Jasper's BME is the most ambitious yet. In 90 chapters, the book considers the role of interactions between neurons, synapses, and glia in the initiation, spread and arrest of seizures. It examines mechanisms of excitability, synchronization, seizure susceptibility, and ultimately epileptogenesis. It provides a framework for expanding the epilepsy genome and understanding the complex heredity responsible for common epilepsies as it explores disease mechanisms of ion channelopathies and developmental epilepsy genes. It considers the mechanisms of conditions of epilepsy comorbidities. And, for the first time, this 4th edition describes the current efforts to translate the discoveries in epilepsy disease mechanisms into new therapeutic strategies. This book, considered the 'bible' of basic epilepsy research, is essential for the student, the clinician scientist and all research scientists who conduct laboratory-based experimental epilepsy research using cellular, brain slice and animal models, as well as for those interested in related disciplines of neuronal oscillations, network plasticity, and signaling in brain strucutres that include the cortex, hippocampus, and thalamus. In keeping with the 1969 goals, the book is now of practical importance to the clinical neurologist and epileptologist as the progress of research in molecular genetics and modern efforts to design antiepileptic drugs, cures and repairs in the epilepsies converge and impact clinical care.

Hormones and Synapse

Hormones and Synapse
Author: Gerald Litwack
Publsiher: Academic Press
Total Pages: 346
Release: 2020-07-26
ISBN 10: 0128220260
ISBN 13: 9780128220269
Language: EN, FR, DE, ES & NL

Hormones and Synapse Book Review:

Hormones and Synapse, Volume 114 in the Vitamins and Hormones series, highlights advances in the field, with this new volume presenting timely topics, including how growth hormone promotes synaptogenesis, sex hormones and proteins involved in brain plasticity, corticotropin releasing factor modulates excitatory synaptic transmission, bisphenol a and memory: a role for dendritic spines, brain insulin resistance impairs hippocampal synaptic plasticity, estradiol induces synaptic rearrangements, stress and remodeling of hippocampal spine synapses, neurotrophin-3 modulates synaptic transmission, nongenomic neurosteroid modulation of hippocampal dendritic spines, neural sex steroids and hippocampal synaptic plasticity, origin of chemical synapses, neural sex steroids and hippocampal synaptic plasticity, and much more. Provides the authority and expertise of leading contributors from an international board of authors Presents the latest release in the Vitamins and Hormones series Includes the latest information on Hormones and Synapse