Stem Cell Innovation in Health Disease The Lung Volume 2

Stem Cell Innovation in Health   Disease  The Lung  Volume 2
Author: Ahmed El-Hashash
Publsiher: Academic Press
Total Pages: 174
Release: 2021-06-10
ISBN 10: 0128212071
ISBN 13: 9780128212073
Language: EN, FR, DE, ES & NL

Stem Cell Innovation in Health Disease The Lung Volume 2 Book Review:

In the lung, more recent data have been accumulated on lung stem cell biology/function and the potential applications of stem cells in pulmonary diseases that are facilitated by the recent development of a broad range of cutting edge in vitro and in vivo research tools and approaches, including mouse and human organoid cultures, genetic editing in vitro and in vivo, human induced pluripotent cell (iPS cell) models of disease, haploid cells for genetic as well as compound screening paradigms, genetically engineered mice, and stem cell transplantation to cure diseases. Stem Cell Innovation in Health and Disease: Volume 2: The Lung, contains two major sections describing cutting edge research for understanding stem cell functions in the lung and respiratory system, and for developing methods to bring stem cells from bench to bedside; respectively. Each section includes insights ranging from using mouse and human organoid cultures, genetic editing in vitro and in vivo, and human induced pluripotent cells (iPSCs) to study stem cell functions and model lung diseases, through the cutting-edge research aiming to bring stem cells from bench to bedside, including the potential application of iPSCs, ESCs and blood stem cells (stem cell transplants) in the treatment of lung diseases/disorders. This book, therefore, discusses the fact-based promise of stem cells and regenerative medicine in the lung in the real world. Provides intensive scientific background and most recent information on cutting edge research to understand respiratory stem cell functions and develop methods to bring stem cells from bench to bedside for different lung diseases Analyzes the current state, opportunities, and challenges of innovative technologies and stem cells from bench to bed, including organoids and iPSC-derived alveolar epithelia cell therapy in the lung Contains two major sections describing cutting-edge research for understanding stem cell functions and for developing methods specific to the lung

The Lung

The Lung
Author: Ahmed El-Hashash
Publsiher: Elsevier
Total Pages: 174
Release: 2021-06-29
ISBN 10: 0128212063
ISBN 13: 9780128212066
Language: EN, FR, DE, ES & NL

The Lung Book Review:

In the lung, more recent data have been accumulated on lung stem cell biology/function and the potential applications of stem cells in pulmonary diseases that are facilitated by the recent development of a broad range of cutting edge in vitro and in vivo research tools and approaches, including mouse and human organoid cultures, genetic editing in vitro and in vivo, human induced pluripotent cell (iPS cell) models of disease, haploid cells for genetic as well as compound screening paradigms, genetically engineered mice, and stem cell transplantation to cure diseases. Stem Cell Innovation in Health and Disease: Volume 2: The Lung, contains two major sections describing cutting edge research for understanding stem cell functions in the lung and respiratory system, and for developing methods to bring stem cells from bench to bedside; respectively. Each section includes insights ranging from using mouse and human organoid cultures, genetic editing in vitro and in vivo, and human induced pluripotent cells (iPSCs) to study stem cell functions and model lung diseases, through the cutting-edge research aiming to bring stem cells from bench to bedside, including the potential application of iPSCs, ESCs and blood stem cells (stem cell transplants) in the treatment of lung diseases/disorders. This book, therefore, discusses the fact-based promise of stem cells and regenerative medicine in the lung in the real world. Provides intensive scientific background and most recent information on cutting edge research to understand respiratory stem cell functions and develop methods to bring stem cells from bench to bedside for different lung diseases Analyzes the current state, opportunities, and challenges of innovative technologies and stem cells from bench to bed, including organoids and iPSC-derived alveolar epithelia cell therapy in the lung Contains two major sections describing cutting-edge research for understanding stem cell functions and for developing methods specific to the lung

The Intestine

The Intestine
Author: Ahmed El-Hashash,Eiman Abdel Meguid
Publsiher: Academic Press
Total Pages: 204
Release: 2021-06-15
ISBN 10: 0128212713
ISBN 13: 9780128212714
Language: EN, FR, DE, ES & NL

The Intestine Book Review:

The intestine is among the leading organs, in which several cutting edge in vitro and in vivo research tools and approaches have recently been developed and used to investigate stem cell biology/function, and the potential applications of stem cells in the treatment of intestinal diseases. These cutting-edge research tools and approaches involve human and murine organoid cultures, genetic editing in vitro and in vivo, human induced pluripotent cell (iPS cell) models of disease, haploid cells for genetic as well as compound screening paradigms, genetically engineered mice, and stem cell transplantation to cure diseases. Stem Cell Innovation in Health and Disease: Volume 1: The Intestine contains two major sections describing cutting edge research for understanding stem cell functions in the intestine, and for developing methods to bring stem cells from bench to bedside; respectively. Each section includes insights ranging from using mouse and human organoid cultures, genetic editing in vitro and in vivo, and human induced pluripotent cells (iPSCs) to study stem cell functions and model intestinal diseases, through the cutting-edge research, including the potential application of iPSCs, ESCs and blood stem cells (stem cell transplants) in the treatment of intestinal diseases/disorders. This volume, therefore, discusses the fact-based promise of stem cells and regenerative medicine in the intestine in the real world. Provides intensive scientific background and most recent information on cutting edge research to understand intestinal stem cell functions and develop methods to bring stem cells from bench to bedside for different intestinal diseases Analyzes the current state, opportunities, and challenges of innovative technologies and stem cells from bench to bed, including organoids and the CRISPR gene editing system in the intestine Contains two major sections describing cutting-edge research for understanding stem cell functions and for developing methods specific to the intestine

Lung Stem Cells in Development Health and Disease

Lung Stem Cells in Development  Health and Disease
Author: Nikolic, Marko Z.,Hogan, Brigid L.M.
Publsiher: European Respiratory Society
Total Pages: 392
Release: 2021-04-01
ISBN 10: 1849841349
ISBN 13: 9781849841344
Language: EN, FR, DE, ES & NL

Lung Stem Cells in Development Health and Disease Book Review:

Most organs in the adult human body are able to maintain themselves and undergo repair after injury; these processes are largely dependent on stem cells. In this Monograph, the Guest Editors bring together leading authors in the field to provide information about the different classes of stem cells present both in the developing and adult lung: where they are found, how they function in homeostasis and pathologic conditions, the mechanisms that regulate their behaviour, and how they may be harnessed for therapeutic purposes. The book focuses on stem cells in the mouse and human lung but also includes the ferret as an increasingly important new model organism. Chapters also discuss how lung tissue, including endogenous stem cells, can be generated in vitro from pluripotent stem cell lines. This state-of-the-art collection comprehensively covers one of the most exciting areas of respiratory science

Addressing Sickle Cell Disease

Addressing Sickle Cell Disease
Author: National Academies of Sciences, Engineering, and Medicine,Health and Medicine Division,Board on Population Health and Public Health Practice,Committee on Addressing Sickle Cell Disease: A Strategic Plan and Blueprint for Action
Publsiher: National Academies Press
Total Pages: 522
Release: 2021-01-22
ISBN 10: 030966960X
ISBN 13: 9780309669603
Language: EN, FR, DE, ES & NL

Addressing Sickle Cell Disease Book Review:

Sickle cell disease (SCD) is a genetic condition that affects approximately 100,000 people in the United States and millions more globally. Individuals with SCD endure the psychological and physiological toll of repetitive pain as well as side effects from the pain treatments they undergo. Some adults with SCD report reluctance to use health care services, unless as a last resort, due to the racism and discrimination they face in the health care system. Additionally, many aspects of SCD are inadequately studied, understood, and addressed. Addressing Sickle Cell Disease examines the epidemiology, health outcomes, genetic implications, and societal factors associated with SCD and sickle cell trait (SCT). This report explores the current guidelines and best practices for the care of patients with SCD and recommends priorities for programs, policies, and research. It also discusses limitations and opportunities for developing national SCD patient registries and surveillance systems, barriers in the healthcare sector associated with SCD and SCT, and the role of patient advocacy and community engagement groups.

Innovative In Vitro Models for Pulmonary Physiology and Drug Delivery in Health and Disease

Innovative In Vitro Models for Pulmonary Physiology and Drug Delivery in Health and Disease
Author: Josue Sznitman,Claus-Michael Lehr,Leslie Yeo
Publsiher: Frontiers Media SA
Total Pages: 135
Release: 2021-12-28
ISBN 10: 2889718611
ISBN 13: 9782889718610
Language: EN, FR, DE, ES & NL

Innovative In Vitro Models for Pulmonary Physiology and Drug Delivery in Health and Disease Book Review:

Promoting Access to Medical Technologies and Innovation Intersections between Public Health Intellectual Property and Trade

Promoting Access to Medical Technologies and Innovation   Intersections between Public Health  Intellectual Property and Trade
Author: World Intellectual Property Organization
Publsiher: WIPO
Total Pages: 257
Release: 2013
ISBN 10: 9280523082
ISBN 13: 9789280523089
Language: EN, FR, DE, ES & NL

Promoting Access to Medical Technologies and Innovation Intersections between Public Health Intellectual Property and Trade Book Review:

This study has emerged from an ongoing program of trilateral cooperation between WHO, WTO and WIPO. It responds to an increasing demand, particularly in developing countries, for strengthened capacity for informed policy-making in areas of intersection between health, trade and IP, focusing on access to and innovation of medicines and other medical technologies.

Principles of Regenerative Medicine

Principles of Regenerative Medicine
Author: Anthony Atala,Robert Lanza,James A. Thomson,Robert Nerem
Publsiher: Academic Press
Total Pages: 1202
Release: 2010-12-16
ISBN 10: 9780123814234
ISBN 13: 0123814235
Language: EN, FR, DE, ES & NL

Principles of Regenerative Medicine Book Review:

Virtually any disease that results from malfunctioning, damaged, or failing tissues may be potentially cured through regenerative medicine therapies, by either regenerating the damaged tissues in vivo, or by growing the tissues and organs in vitro and implanting them into the patient. Principles of Regenerative Medicine discusses the latest advances in technology and medicine for replacing tissues and organs damaged by disease and of developing therapies for previously untreatable conditions, such as diabetes, heart disease, liver disease, and renal failure. Key for all researchers and instituions in Stem Cell Biology, Bioengineering, and Developmental Biology The first of its kind to offer an advanced understanding of the latest technologies in regenerative medicine New discoveries from leading researchers on restoration of diseased tissues and organs

The Fourth Industrial Revolution

The Fourth Industrial Revolution
Author: Klaus Schwab
Publsiher: Currency
Total Pages: 184
Release: 2017
ISBN 10: 1524758868
ISBN 13: 9781524758868
Language: EN, FR, DE, ES & NL

The Fourth Industrial Revolution Book Review:

Between the 18th and 19th centuries, Britain experienced massive leaps in technological, scientific, and economical advancement

Cardiac Regeneration

Cardiac Regeneration
Author: Masaki Ieda,Wolfram-Hubertus Zimmermann
Publsiher: Springer
Total Pages: 274
Release: 2017-10-27
ISBN 10: 3319561065
ISBN 13: 9783319561066
Language: EN, FR, DE, ES & NL

Cardiac Regeneration Book Review:

This Volume of the series Cardiac and Vascular Biology offers a comprehensive and exciting, state-of-the-art work on the current options and potentials of cardiac regeneration and repair. Several techniques and approaches have been developed for heart failure repair: direct injection of cells, programming of scar tissue into functional myocardium, and tissue-engineered heart muscle support. The book introduces the rationale for these different approaches in cell-based heart regeneration and discusses the most important considerations for clinical translation. Expert authors discuss when, why, and how heart muscle can be salvaged. The book represents a valuable resource for stem cell researchers, cardiologists, bioengineers, and biomedical scientists studying cardiac function and regeneration.

Stem Cell Based Therapy for Lung Disease

Stem Cell Based Therapy for Lung Disease
Author: Janette K. Burgess,Irene H. Heijink
Publsiher: Springer Nature
Total Pages: 259
Release: 2019-11-23
ISBN 10: 303029403X
ISBN 13: 9783030294038
Language: EN, FR, DE, ES & NL

Stem Cell Based Therapy for Lung Disease Book Review:

This book presents state-of-the-art pre-clinical models and clinical applications of stem-cell-based therapies applied to different lung diseases, with a special focus on the translation of bench data into clinical studies. Starting with the assumption that abnormal lung tissue repair and regeneration has emerged as the driving force underlying pathogenesis and progression in many lung diseases, it sheds new light on the potential of stem/stromal cells as drivers of repair and sources of reparative factors in the lung. The first part of the book offers an overview of stem cell types and mechanisms involved in lung development, homeostasis, repair and regeneration, and reveals the crucial role of the extracellular matrix within the lung microenvironment. In the second part, leading experts present the latest pre-clinical evidence and clinical applications of stem-cell-based therapies in a wide variety of lung diseases, ranging from COPD and lung fibrosis to other rare lung diseases. The last section discusses stem cell delivery systems and devices, such as aerosolised spray application. This book appeals to pneumologists, stem cell and matrix biologists, as well as bioengeneers with a special interest in regenerative medicine applied to pulmonary diseases.

Departments of Labor Health and Human Services Education and Related Agencies Appropriations for 2015

Departments of Labor  Health and Human Services  Education  and Related Agencies Appropriations for 2015
Author: United States. Congress. House. Committee on Appropriations. Subcommittee on the Departments of Labor, Health and Human Services, Education, and Related Agencies
Publsiher: Unknown
Total Pages: 135
Release: 2014
ISBN 10: 1928374650XXX
ISBN 13: STANFORD:36105050675342
Language: EN, FR, DE, ES & NL

Departments of Labor Health and Human Services Education and Related Agencies Appropriations for 2015 Book Review:

Disease Control Priorities Third Edition Volume 6

Disease Control Priorities  Third Edition  Volume 6
Author: King K. Holmes,Stefano Bertozzi,Barry Bloom
Publsiher: Disease Control Priorities
Total Pages: 506
Release: 2017-11-03
ISBN 10: 9781464805240
ISBN 13: 1464805245
Language: EN, FR, DE, ES & NL

Disease Control Priorities Third Edition Volume 6 Book Review:

Infectious diseases are the leading cause of death globally, particularly among children and young adults. The spread of new pathogens and the threat of antimicrobial resistance pose particular challenges in combating these diseases. Major Infectious Diseases identifies feasible, cost-effective packages of interventions and strategies across delivery platforms to prevent and treat HIV/AIDS, other sexually transmitted infections, tuberculosis, malaria, adult febrile illness, viral hepatitis, and neglected tropical diseases. The volume emphasizes the need to effectively address emerging antimicrobial resistance, strengthen health systems, and increase access to care. The attainable goals are to reduce incidence, develop innovative approaches, and optimize existing tools in resource-constrained settings.

Mesenchymal Stem Cell Therapy

Mesenchymal Stem Cell Therapy
Author: Lucas G. Chase,Mohan C Vemuri
Publsiher: Springer Science & Business Media
Total Pages: 456
Release: 2012-12-12
ISBN 10: 1627032002
ISBN 13: 9781627032001
Language: EN, FR, DE, ES & NL

Mesenchymal Stem Cell Therapy Book Review:

Over the past decade, significant efforts have been made to develop stem cell-based therapies for difficult to treat diseases. Multipotent mesenchymal stromal cells, also referred to as mesenchymal stem cells (MSCs), appear to hold great promise in regards to a regenerative cell-based therapy for the treatment of these diseases. Currently, more than 200 clinical trials are underway worldwide exploring the use of MSCs for the treatment of a wide range of disorders including bone, cartilage and tendon damage, myocardial infarction, graft-versus-host disease, Crohn’s disease, diabetes, multiple sclerosis, critical limb ischemia and many others. MSCs were first identified by Friendenstein and colleagues as an adherent stromal cell population within the bone marrow with the ability to form clonogenic colonies in vitro. In regards to the basic biology associated with MSCs, there has been tremendous progress towards understanding this cell population’s phenotype and function from a range of tissue sources. Despite enormous progress and an overall increased understanding of MSCs at the molecular and cellular level, several critical questions remain to be answered in regards to the use of these cells in therapeutic applications. Clinically, both autologous and allogenic approaches for the transplantation of MSCs are being explored. Several of the processing steps needed for the clinical application of MSCs, including isolation from various tissues, scalable in vitro expansion, cell banking, dose preparation, quality control parameters, delivery methods and numerous others are being extensively studied. Despite a significant number of ongoing clinical trials, none of the current therapeutic approaches have, at this point, become a standard of care treatment. Although exceptionally promising, the clinical translation of MSC-based therapies is still a work in progress. The extensive number of ongoing clinical trials is expected to provide a clearer path forward for the realization and implementation of MSCs in regenerative medicine. Towards this end, reviews of current clinical trial results and discussions of relevant topics association with the clinical application of MSCs are compiled in this book from some of the leading researchers in this exciting and rapidly advancing field. Although not absolutely all-inclusive, we hope the chapters within this book can promote and enable a better understanding of the translation of MSCs from bench-to-bedside and inspire researchers to further explore this promising and quickly evolving field.

Catalog of Federal Domestic Assistance

Catalog of Federal Domestic Assistance
Author: Anonim
Publsiher: Unknown
Total Pages: 135
Release: 2007
ISBN 10: 1928374650XXX
ISBN 13: OSU:32437122994672
Language: EN, FR, DE, ES & NL

Catalog of Federal Domestic Assistance Book Review:

Identifies and describes specific government assistance opportunities such as loans, grants, counseling, and procurement contracts available under many agencies and programs.

Medical Applications of iPS Cells

Medical Applications of iPS Cells
Author: Haruhisa Inoue,Yukio Nakamura
Publsiher: Springer
Total Pages: 190
Release: 2019-04-01
ISBN 10: 9811336725
ISBN 13: 9789811336720
Language: EN, FR, DE, ES & NL

Medical Applications of iPS Cells Book Review:

This volume highlights recent advances using iPS cells in disease modeling and medical applications along with new technologies that enhance the power of iPS cells. While the discovery of iPS cells has provided excellent opportunities for developing models of human diseases, platforms for drug discovery and cell therapies, iPS cell technology still faces many challenges. Presenting the latest advances in this rapidly evolving research area, this book is intended to widen the community of researchers and clinicians interested in the exciting field of iPS cells.

Medicinal Plants for Lung Diseases

Medicinal Plants for Lung Diseases
Author: Kamal Dua,Srinivas Nammi,Dennis Chang,Dinesh Kumar Chellappan,Gaurav Gupta,Trudi Collet
Publsiher: Springer Nature
Total Pages: 622
Release: 2021-07-30
ISBN 10: 9813368500
ISBN 13: 9789813368507
Language: EN, FR, DE, ES & NL

Medicinal Plants for Lung Diseases Book Review:

This book summarizes experimentally-supported research on the therapeutic efficacy of plant extracts and their constituents on a range of respiratory diseases including infections. It discusses the pharmacological, cellular and molecular factors involved in the pathogenies of respiratory diseases and their modulation by plant-derived compounds. Additionally, it underlines the growing relevance of medicinal plant-based advanced drug delivery systems for treating lung diseases providing maximal therapeutic efficacy with better patient compliance. Overall, this comprehensive book is a blend of translational, biological, chemical and drug delivery aspects of medicinal plants employed in targeting respiratory diseases and attracts a range of audiences including physiochemist, translational and clinical researchers working in the field of respiratory diseases.

Medical Innovation and Disease Burden

Medical Innovation and Disease Burden
Author: Sobin George
Publsiher: Cambridge University Press
Total Pages: 240
Release: 2021-02-28
ISBN 10: 110883230X
ISBN 13: 9781108832304
Language: EN, FR, DE, ES & NL

Medical Innovation and Disease Burden Book Review:

Drawing from recent concepts and data, the book carefully examines responsiveness of drug, vaccine and medical device innovations to public health priorities in India. It also emphasises the need for a responsible and responsive health innovation framework in which interests of all stakeholders are taken care of.

The SAGE Encyclopedia of Stem Cell Research

The SAGE Encyclopedia of Stem Cell Research
Author: Eric E. Bouhassira
Publsiher: SAGE Publications
Total Pages: 1552
Release: 2015-06-15
ISBN 10: 1483347672
ISBN 13: 9781483347677
Language: EN, FR, DE, ES & NL

The SAGE Encyclopedia of Stem Cell Research Book Review:

The SAGE Encyclopedia of Stem Cell Research, Second Edition is filled with new procedures and exciting medical breakthroughs, including executive orders from the Obama administration reversing barriers to research imposed under the Bush administration, court rulings impacting NIH funding of research based on human embryonic stem cells, edicts by the Papacy and other religious leaders, and the first success in cloning human stem cells. Stem cell biology is clearly fueling excitement and potential in traditional areas of developmental biology and in the field of regenerative medicine, where they are believed to hold much promise in addressing any number of intractable medical conditions. This updated second edition encyclopedia will expand on information that was given in the first edition and present more than 270 new and updated articles that explore major topics in ways accessible to nonscientists, thus bringing readers up-to-date with where stem cell biology stands today, including new and evolving ethical, religious, legal, social, and political perspectives. This second edition reference work will serve as a universal resource for all public and academic libraries. It is an excellent foundation for anyone who is interested in the subject area of stem cell biology. Key Features: Reader’s Guide, Further Readings, Cross References, Chronology, Resource Guide, Index A Glossary will elucidate stem cell terminology for the nonscientist Statistics and selected reprints of major journal articles that pertain to milestones achieved in stem cell research Documents from Congressional Hearings on stem cells and cloning Reports to the President’s Council on Bioethics, and more

Mesenchymal Stem Cells in Human Health and Diseases

Mesenchymal Stem Cells in Human Health and Diseases
Author: Ahmed El-Hashash
Publsiher: Academic Press
Total Pages: 228
Release: 2020-01-06
ISBN 10: 0128197137
ISBN 13: 9780128197134
Language: EN, FR, DE, ES & NL

Mesenchymal Stem Cells in Human Health and Diseases Book Review:

Mesenchymal Stem Cells in Human Health and Diseases provides a contemporary overview of the fast-moving field of MSC biology, regenerative medicine and therapeutics. MSCs offer the potential to dramatically reduce human suffering from disease. Numerous MSC-based studies are ongoing each year, each offering hope for novel treatments in human disease. This book provides information on MSC application in well-studied human diseases and tissue repair/regeneration and recent advances in their research and treatment. These discoveries are placed within the structural context of tissue and developmental biology in sections dealing with recent advances in our understanding of MSC biology. Includes insights ranging from MSC biology and development through the derivation and identification and properties of MSCs Helps to identify potential innovative solutions for restoring normal morphogenesis and/or regeneration of diseased organs Discusses the fact-based promise of MSC therapeutics and regenerative medicine in the real world