Sex and Gender Differences in Alzheimer s Disease

Sex and Gender Differences in Alzheimer s Disease
Author: Maria Teresa Ferretti,Annemarie Schumacher Dimech,Antonella Santuccione Chadha
Publsiher: Elsevier
Total Pages: 512
Release: 2021-08-19
ISBN 10: 0128193441
ISBN 13: 9780128193440
Language: EN, FR, DE, ES & NL

Sex and Gender Differences in Alzheimer s Disease Book Review:

Sex and Gender Differences in Alzheimer's Disease: The Women's Brain Project offers, for the first time, a critical overview of the evidence documenting sex and gender differences in AD neurobiology, biomarkers, clinical presentation, treatment, clinical trials and their outcomes and impact on caregivers. This knowledge is crucial for clinical development, digital health solutions, and as social and psychological support to AD families. Presents comprehensive and critical reviews of sex differences in Alzheimer's disease Combines the knowledge and points-of-view of neuroscientists, medical doctors, psychologists and AI experts for a 360 degree view on the topic and its possible implications Edited by the Women's Brain Project, the leading NGO in the field of sex differences in neuroscience

Sex Differences in Neurology and Psychiatry

Sex Differences in Neurology and Psychiatry
Author: Anonim
Publsiher: Elsevier
Total Pages: 476
Release: 2020-09-30
ISBN 10: 0444641246
ISBN 13: 9780444641243
Language: EN, FR, DE, ES & NL

Sex Differences in Neurology and Psychiatry Book Review:

Sex Differences in Neurology and Psychiatry, Volume 175, addresses this important issue by viewing major neurological and psychiatric conditions through the lens of sexual dimorphism, providing an entirely novel approach to understanding vulnerability factors, as well as potential new treatment strategies in several common neuropsychiatric disorders. The handbook comprises four major sections: (1) Introduction to sex differences in neuroanatomy and neurophysiology, (2) Description of the impact of genetic, epigenetic, sex hormonal and other environmental effects on cerebral sex dimorphism, (3) Review of sex differences in neurologic disorders, and (4) Review of sex differences in psychiatric disorders. Explores sex differences in human neuroanatomy and neurophysiology Offers a pathway toward a gender-specific treatment of neurologic and psychiatric disorders Provides an overview of the genetics of sex hormones, human brain structure, and function, as well as the epigenetics, environment and social context

Sex and Gender Differences in Alzheimer s Disease

Sex and Gender Differences in Alzheimer s Disease
Author: Maria Teresa Ferretti,Annemarie Schumacher Dimech,Antonella Santuccione Chadha
Publsiher: Academic Press
Total Pages: 512
Release: 2021-07-23
ISBN 10: 012819345X
ISBN 13: 9780128193457
Language: EN, FR, DE, ES & NL

Sex and Gender Differences in Alzheimer s Disease Book Review:

Sex and Gender Differences in Alzheimer’s Disease: The Women’s Brain Project offers for the first time a critical overview of the evidence documenting sex and gender differences in Alzheimer’s disease neurobiology, biomarkers, clinical presentation, treatment, clinical trials and their outcomes, and socioeconomic impact on both patients and caregivers. This knowledge is crucial for clinical development, digital health solutions, as well as social and psychological support to Alzheimer’s disease families, in the frame of a precision medicine approach to Alzheimer’s disease. This book brings together up-to-date findings from a variety of experts, covering basic neuroscience, epidemiology, diagnosis, treatment, clinical trials development, socioeconomic factors, and psychosocial support. Alzheimer’s disease, the most common form of dementia, remains an unmet medical need for the planet. Wide interpersonal variability in disease onset, presentation, and biomarker profile make Alzheimer’s a clinical challenge to neuroscientists, clinicians, and drug developers alike, resulting in huge management costs for health systems and society. Not only do women represent the majority of Alzheimer’s disease patients, but they also represent two-thirds of caregivers. Understanding sex and gender differences in Alzheimer’s disease will lead to novel insights into disease mechanisms, and will be crucial for personalized disease management strategies and solutions, involving both the patient and their family. Provides a comprehensive and critical review of sex differences in Alzheimer’s disease Features discussion of sex and gender differences in disease biology, treatment, and socioeconomic factors, including impact on caregivers Combines the knowledge and points-of-view of neuroscientists, medical doctors, psychologists, policymakers, health scientists, and clinical trial experts, for a 360-degree view on the topic and its possible implications Edited by the Women’s Brain Project, the leading NGO in the field of sex and gender differences in brain and mental health as the gateway to precision medicine

Sex Differences in Physiology

Sex Differences in Physiology
Author: Gretchen Neigh,Megan Mitzelfelt
Publsiher: Academic Press
Total Pages: 236
Release: 2016-05-10
ISBN 10: 0128026081
ISBN 13: 9780128026083
Language: EN, FR, DE, ES & NL

Sex Differences in Physiology Book Review:

Sex Differences in Physiology is an all-encompassing reference that details basic science research into sex differences in all physiological fields. It includes scientific discoveries concerning sex differences in cardiovascular, respiratory, renal, gastrointestinal, and musculoskeletal physiology. In addition, coverage of the development, endocrinology, neurophysiology, immunity, and metabolism is included, making this important reference a resource that will meet the needs of investigators interested in incorporating sex differences into their research programs, while also providing clinicians with the basis for providing the best sex-based medical treatment options available. Provides a sweeping, organ-by-organ review of currently observed sex differences in animal models and human disease Explains how sex differences influence physiology and disease Provides the critical knowledge on sex differences for better understanding of prevention and treatment of diseases

Sex and Gender Differences in Neurological Disease

Sex and Gender Differences in Neurological Disease
Author: Anonim
Publsiher: Academic Press
Total Pages: 394
Release: 2022-08-27
ISBN 10: 0323915906
ISBN 13: 9780323915908
Language: EN, FR, DE, ES & NL

Sex and Gender Differences in Neurological Disease Book Review:

International Review on Neurobiology serial highlights new advances in the field with this new volume presenting interesting chapters. Each chapter is written by an international board of authors. Provides the authority and expertise of leading contributors from an international board of authors Presents the latest release in International Review on Neurobiology serials Updated release includes the latest information on Sex and Gender Differences in Neurological Disease

Bridging Gaps Between Sex and Gender in Neurosciences

Bridging Gaps Between Sex and Gender in Neurosciences
Author: Annie Duchesne,Meng-Chuan Lai,Gillian Einstein,Belinda Pletzer,Marina A. Pavlova
Publsiher: Frontiers Media SA
Total Pages: 135
Release: 2020-07-14
ISBN 10: 2889638650
ISBN 13: 9782889638659
Language: EN, FR, DE, ES & NL

Bridging Gaps Between Sex and Gender in Neurosciences Book Review:

Women s Health Research

Women s Health Research
Author: Institute of Medicine,Board on Population Health and Public Health Practice,Committee on Women's Health Research
Publsiher: National Academies Press
Total Pages: 438
Release: 2010-10-27
ISBN 10: 9780309163378
ISBN 13: 0309163374
Language: EN, FR, DE, ES & NL

Women s Health Research Book Review:

Even though slightly over half of the U.S. population is female, medical research historically has neglected the health needs of women. However, over the past two decades, there have been major changes in government support of women's health research--in policies, regulations, and the organization of research efforts. To assess the impact of these changes, Congress directed the Department of Health and Human Services (HHS) to ask the IOM to examine what has been learned from that research and how well it has been put into practice as well as communicated to both providers and women. Women's Health Research finds that women's health research has contributed to significant progress over the past 20 years in lessening the burden of disease and reducing deaths from some conditions, while other conditions have seen only moderate change or even little or no change. Gaps remain, both in research areas and in the application of results to benefit women in general and across multiple population groups. Given the many and significant roles women play in our society, maintaining support for women's health research and enhancing its impact are not only in the interest of women, they are in the interest of us all.

Sex Hormones in Neurodegenerative Processes and Diseases

Sex Hormones in Neurodegenerative Processes and Diseases
Author: Gorazd Drevensek
Publsiher: BoD – Books on Demand
Total Pages: 358
Release: 2018-05-02
ISBN 10: 1789230144
ISBN 13: 9781789230147
Language: EN, FR, DE, ES & NL

Sex Hormones in Neurodegenerative Processes and Diseases Book Review:

The book provides chapters on sex hormones and their modulation in neurodegenerative processes and pathologies, from basic molecular mechanisms, physiology, gender differences, to neuroprotection and clinical aspects for potential novel pharmacotherapy approaches. The book contains 14 chapters written by authors from various biomedical professions, from basic researchers in biology and physiology to medicine and veterinary medicine, pharmacologists, psychiatrist, etc. Chapters sum up the past and current knowledge on sex hormones, representing original new insights into their role in brain functioning, mental disorders and neurodegenerative diseases. The book is written for a broad range of audience, from biomedical students to highly profiled medical specialists and biomedical researchers, helping them to expand their knowledge on sex hormones in neurodegenerative processes and opening new questions for further investigation.

How Sex and Gender Impact Clinical Practice

How Sex and Gender Impact Clinical Practice
Author: Marjorie Jenkins,Connie B. Newman
Publsiher: Academic Press
Total Pages: 360
Release: 2020-12-02
ISBN 10: 0128167505
ISBN 13: 9780128167502
Language: EN, FR, DE, ES & NL

How Sex and Gender Impact Clinical Practice Book Review:

How Sex and Gender Impact Clinical Practice: An Evidence-Based Guide to Patient Care enables primary care clinicians by providing a framework to understand differences and better care for patients in their practice. Each chapter covers a subspecialty in medicine and discusses the influence of sex hormones on disease, along with sex and gender-based differences in clinical presentation, physical examination, laboratory results, treatment regimens, comorbidities and prognosis. Illustrative case examples and practical practice points help each chapter come alive. A special chapter on communication differences between men and women assists clinicians in their conversations with patients. This book fills an important need by applying years of research findings to sex and gender specific medical care and demonstrating that an individualized approach to patient care will lead to improved detection, treatment and prevention of disease. Explores the effects of sex and gender on disease presentation, treatment and prognosis, and how these differences influence clinical decision-making Provides practical guidance that helps clinicians implement a more individualized approach to patient care Contains information on diseases in each major specialty, as well as chapters on communication, pharmacology and public health challenges

Exploring the Biological Contributions to Human Health

Exploring the Biological Contributions to Human Health
Author: Institute of Medicine,Board on Health Sciences Policy,Committee on Understanding the Biology of Sex and Gender Differences
Publsiher: National Academies Press
Total Pages: 288
Release: 2001-07-02
ISBN 10: 9780309132978
ISBN 13: 0309132975
Language: EN, FR, DE, ES & NL

Exploring the Biological Contributions to Human Health Book Review:

It's obvious why only men develop prostate cancer and why only women get ovarian cancer. But it is not obvious why women are more likely to recover language ability after a stroke than men or why women are more apt to develop autoimmune diseases such as lupus. Sex differences in health throughout the lifespan have been documented. Exploring the Biological Contributions to Human Health begins to snap the pieces of the puzzle into place so that this knowledge can be used to improve health for both sexes. From behavior and cognition to metabolism and response to chemicals and infectious organisms, this book explores the health impact of sex (being male or female, according to reproductive organs and chromosomes) and gender (one's sense of self as male or female in society). Exploring the Biological Contributions to Human Health discusses basic biochemical differences in the cells of males and females and health variability between the sexes from conception throughout life. The book identifies key research needs and opportunities and addresses barriers to research. Exploring the Biological Contributions to Human Health will be important to health policy makers, basic, applied, and clinical researchers, educators, providers, and journalists-while being very accessible to interested lay readers.

A Demographic Perspective on Gender Family and Health in Europe

A Demographic Perspective on Gender  Family and Health in Europe
Author: Gabriele Doblhammer,Jordi Gumà
Publsiher: Springer
Total Pages: 303
Release: 2018-02-12
ISBN 10: 3319723561
ISBN 13: 9783319723563
Language: EN, FR, DE, ES & NL

A Demographic Perspective on Gender Family and Health in Europe Book Review:

This open access book examines the triangle between family, gender, and health in Europe from a demographic perspective. It helps to understand patterns and trends in each of the three components separately, as well as their interdependencies. It overcomes the widely observable specialization in demographic research, which usually involves researchers studying either family or fertility processes or focusing on health and mortality. Coverage looks at new family and partnership forms among the young and middle-aged, their relationship with health, and the pathways through which they act. Among the old, lifelong family biography and present family situation are explored. Evidence is provided that partners advancing in age start to resemble each other more closely in terms of health, with the health of the partner being a crucial factor of an individual’s own health. Gender-specific health outcomes and pathways are central in the designs of the studies and the discussion of the results. The book compares twelve European countries reflecting different welfare state regimes and offers country-specific studies conducted in Austria, Germany, Italy - all populations which have received less attention in the past - and Sweden. As a result, readers discover the role of different concepts of family and health as well as comparisons within European countries and ethnic groups. It will be an insightful resource for students, academics, policy makers, and researchers that will help define future research in terms of gender and public health.

Behavioral and Psychological Symptoms of Dementia

Behavioral and Psychological Symptoms of Dementia
Author: Art Walaszek, M.D.
Publsiher: American Psychiatric Pub
Total Pages: 284
Release: 2019-08-28
ISBN 10: 1615371680
ISBN 13: 9781615371686
Language: EN, FR, DE, ES & NL

Behavioral and Psychological Symptoms of Dementia Book Review:

The number of geriatric psychiatrists, specialty fellowships, and practices has been declining relative to the increase in the number of older adults in the United States; critical shortages in care are the new norm. Behavioral and Psychological Symptoms of Dementia was designed to address this predicament by enabling primary care providers to access a solid knowledge base and the clinical experience required to meet the needs of their patients with dementia. The author has written a concise yet comprehensive book that covers the full range of behavioral and psychological symptoms of dementia (BPSD) encountered by patients, families, caregivers, and primary care providers. In addition, the book provides the necessary foundation for distinguishing the different types of dementia, critical elements of patient history needed to develop an appropriate treatment approach, and the basic medical examinations and lab work that should be performed. Each chapter begins with a brief précis; well-written descriptions of the major topic follow. The chapters explore the common types of behavioral and emotional symptoms and the important associated system issues relevant to dementia care, including elder abuse reporting, creation of advance directives and power of attorney arrangements, safety planning, and caregiver support.The book's strengths are many * Carefully chosen, realistic case examples bring the material to life in a vivid, compelling way.* An up-to-date review of the literature is presented, striking an appropriate balance between new and promising findings and current standard-of-care practices. The book also identifies significant gaps in the literature.* Standard-of-care pharmacological and psychosocial approaches in the management of BPSD are offered with a realistic understanding of the benefits and difficulties of implementing each.* Relevant information on complementary medicine is included, and the book covers personality, cultural, and spiritual domains so that the reader is cognizant of the whole-person approach in delivering dementia care.* Each chapter includes key points for quick and easy reference and resources to share with patients, families, and caregivers -- a boon to the busy clinician. * Although intended as a practical guide for clinicians in a variety of fields, those in academia who specialize in geriatric medicine or psychiatry will find the book a useful way to organize and teach this material to students, residents, and fellows. Pragmatic and clinically oriented, Behavioral and Psychological Symptoms of Dementia will help primary care practitioners provide informed, compassionate care to older adults at risk for, or exhibiting, BPSD.

Brain and Heart Dynamics

Brain and Heart Dynamics
Author: Stefano Govoni,Pierluigi Politi,Emilio Vanoli
Publsiher: Springer
Total Pages: 1003
Release: 2020-10-16
ISBN 10: 9783030280079
ISBN 13: 3030280071
Language: EN, FR, DE, ES & NL

Brain and Heart Dynamics Book Review:

This ambitious and comprehensive handbook represents an essential contribution to our current understanding of interactions between heart and brain, a research topic generating growing interest. Despite the increasing awareness that neural mechanisms are the primary cause of cardiac disease and its progression, therapy continues to focus on end-organ protection and does not approach the neural core of the problem. Growing public health problems such as heart failure are still treated with autonomic drugs that are 30-40 years old and simply act on cardiac receptors. However, it has now been shown that the progression of ischemic heart disease to heart failure is mainly due to abnormal central responses to incipient cardiac disease, with neural activation the primary cause rather than the consequence of cardiac remodeling. Written by leading international experts in their respective research areas, the book presents a variety of perspectives on the core topic: from social and philosophical to gender-related aspects. It is designed for a broad readership and includes dedicated sections for cardiologists, psychiatrists, neurologists and psychotherapists looking for a more insightful and targeted approach to neuro-cardiovascular disease.

Hormones Cognition and Dementia

Hormones  Cognition and Dementia
Author: Eef Hogervorst,Victor W. Henderson,Robert B. Gibbs,Roberta Diaz Brinton
Publsiher: Cambridge University Press
Total Pages: 135
Release: 2009-09-24
ISBN 10: 113948365X
ISBN 13: 9781139483650
Language: EN, FR, DE, ES & NL

Hormones Cognition and Dementia Book Review:

A decade ago, oestrogen-containing hormone therapy was viewed as a promising strategy for the prevention and treatment of dementia and age-related cognitive decline. However, treatment trials in women with Alzheimer's disease showed that oestrogens did not reverse cognitive impairment, and clinical trials in healthy older women indicated that oestrogens did not prevent cognitive decline. The Women's Health Initiative Memory Study trial even suggested an increased risk of dementia with treatment late in life. What happened? How are we to understand these findings? What are the implications for middle-aged and older women? What about testosterone, and what about men? And where do we go from here? This book brings together world-renowned experts in basic and clinical research on sex steroids, aging, and cognition to integrate existing findings with emerging new data, and offer challenging hypotheses on these key issues.

The Cambridge Handbook of Visuospatial Thinking

The Cambridge Handbook of Visuospatial Thinking
Author: Priti Shah,Akira Miyake
Publsiher: Cambridge University Press
Total Pages: 561
Release: 2005-07-25
ISBN 10: 9780521807104
ISBN 13: 0521807107
Language: EN, FR, DE, ES & NL

The Cambridge Handbook of Visuospatial Thinking Book Review:

Publisher Description

Drug Discovery and Evaluation Methods in Clinical Pharmacology

Drug Discovery and Evaluation  Methods in Clinical Pharmacology
Author: H.Gerhard Vogel,Jochen Maas,Alexander Gebauer
Publsiher: Springer Science & Business Media
Total Pages: 564
Release: 2010-12-15
ISBN 10: 3540898905
ISBN 13: 9783540898900
Language: EN, FR, DE, ES & NL

Drug Discovery and Evaluation Methods in Clinical Pharmacology Book Review:

Drug Discovery and Evaluation has become a more and more difficult, expensive and time-consuming process. The effect of a new compound has to be detected by in vitro and in vivo methods of pharmacology. The activity spectrum and the potency compared to existing drugs have to be determined. As these processes can be divided up stepwise we have designed a book series "Drug Discovery and Evaluation" in the form of a recommendation document. The methods to detect drug targets are described in the first volume of this series "Pharmacological Assays" comprising classical methods as well as new technologies. Before going to man, the most suitable compound has to be selected by pharmacokinetic studies and experiments in toxicology. These preclinical methods are described in the second volume „Safety and Pharmacokinetic Assays". Only then are first studies in human beings allowed. Special rules are established for Phase I studies. Clinical pharmacokinetics are performed in parallel with human studies on tolerability and therapeutic effects. Special studies according to various populations and different therapeutic indications are necessary. These items are covered in the third volume: „Methods in Clinical Pharmacology".

Sex and Gender Aspects in Clinical Medicine

Sex and Gender Aspects in Clinical Medicine
Author: Sabine Oertelt-Prigione,Vera Regitz-Zagrosek
Publsiher: Springer Science & Business Media
Total Pages: 204
Release: 2011-11-15
ISBN 10: 9780857298324
ISBN 13: 0857298321
Language: EN, FR, DE, ES & NL

Sex and Gender Aspects in Clinical Medicine Book Review:

This book is a concise, easy to read professional text with a focus on practical aspects. All chapters include tables on sex/gender differences in symptoms and management and a series of suggestions to the novice in the field. Chapters are specialty-specific. The focus is not on women’s health, but the presentation of differences in clinical symptoms, management and outcomes in women and men. Gender Medicine strives to employ the knowledge about these differences to improve diagnosis, better understand pathogenesis and advance patient-oriented therapy.

Neurology and Psychiatry of Women

Neurology and Psychiatry of Women
Author: Mary Angela O’Neal
Publsiher: Springer
Total Pages: 243
Release: 2019-02-14
ISBN 10: 3030042456
ISBN 13: 9783030042455
Language: EN, FR, DE, ES & NL

Neurology and Psychiatry of Women Book Review:

This comprehensive resource covers a range of women’s health issues and their intersection with neurologic and psychiatric disease. Chapters feature high quality, integrated information based on leading-edge research on gender-specific care and are grouped by reproductive years, pregnancy and health, and aging. Emerging science regarding sex differences in neurological and psychiatric illnesses, including anxiety, reproductive health, conversion disorders, depression and ethical issues in pregnancy, stroke risk factors, and successful aging strategies are covered along with clinical application of this knowledge to the delivery of care. In addition, in those medical problems that afflict both men and women, authors will point out the different risks, prevalence, presentations, and responses to treatments or outcomes in women. Written by renowned experts in the field, this textbook will thoroughly address the educational needs of physicians, nurse practitioners, and physician assistants in the areas of neurology, psychiatry, internal medicine, and obstetrics and expanding their understanding of concerns unique to female patients.

Applying Quantitative Bias Analysis to Epidemiologic Data

Applying Quantitative Bias Analysis to Epidemiologic Data
Author: Timothy L. Lash,Matthew P. Fox,Aliza K. Fink
Publsiher: Springer Science & Business Media
Total Pages: 192
Release: 2011-04-14
ISBN 10: 9780387879598
ISBN 13: 0387879595
Language: EN, FR, DE, ES & NL

Applying Quantitative Bias Analysis to Epidemiologic Data Book Review:

Bias analysis quantifies the influence of systematic error on an epidemiology study’s estimate of association. The fundamental methods of bias analysis in epi- miology have been well described for decades, yet are seldom applied in published presentations of epidemiologic research. More recent advances in bias analysis, such as probabilistic bias analysis, appear even more rarely. We suspect that there are both supply-side and demand-side explanations for the scarcity of bias analysis. On the demand side, journal reviewers and editors seldom request that authors address systematic error aside from listing them as limitations of their particular study. This listing is often accompanied by explanations for why the limitations should not pose much concern. On the supply side, methods for bias analysis receive little attention in most epidemiology curriculums, are often scattered throughout textbooks or absent from them altogether, and cannot be implemented easily using standard statistical computing software. Our objective in this text is to reduce these supply-side barriers, with the hope that demand for quantitative bias analysis will follow.

Sex and Gender Differences in Pharmacology

Sex and Gender Differences in Pharmacology
Author: Vera Regitz-Zagrosek
Publsiher: Springer Science & Business Media
Total Pages: 602
Release: 2012-10-02
ISBN 10: 3642307264
ISBN 13: 9783642307263
Language: EN, FR, DE, ES & NL

Sex and Gender Differences in Pharmacology Book Review:

This is the very first book to deal with sex and gender differences in drug therapy - an increasingly recognized medical need. It starts with an overview on S/G in clinical syndromes and a documentation of the medical and socioeconomic damage caused by gender specific adverse drug effects. Part I covers S/G differences in pharmacokinetics. Researchers will be satisfied by the detailed discussion of the mechanisms of S/G differences in drug effects that represents cutting edge science and includes interaction of drugs with sex hormones, genomic and epigenetic mechanisms. It also covers S/G in drug development, in animal models and clinical development and S/G in drug prescriptions. Part II targets S/G differences in drug effects in cardiovascular, pulmonary, CNS, neuromuscular, neuropsychiatric and metabolic diseases, in cancer, inflammation, and rheumatic diseases, in bacterial and retroviral infections, thrombosis, embolism. New drugs will be discussed.