Pedigree Analysis in R

Pedigree Analysis in R
Author: Magnus Dehli Vigeland
Publsiher: Academic Press
Total Pages: 184
Release: 2021-05-06
ISBN 10: 0128245603
ISBN 13: 9780128245606
Language: EN, FR, DE, ES & NL

Pedigree Analysis in R Book Review:

Pedigree Analysis in R gives an introduction to the theory of relatedness and covers a range of applications in forensic and medical genetics. The book's material was developed through teaching courses on genetic relatedness, pedigree analysis and R, and offers insights from a decade of research activities in forensic and medical genetics. The R code in the book uses the ped suite, a unified collection of packages for pedigree analysis, developed by the author. All code examples are given in full, allowing accurate reproduction of figures and results. At the end of each chapter, a selection of exercises encourages the reader to explore further and perform their own analyses. Introduction to the theory of genetic relatedness, richly illustrated with classic and novel examples In-depth case studies including kinship testing, pedigree reconstruction, linkage analysis and clinical segregation analysis Easy-to-follow R code with explanations Based on the ped suite packages for pedigree analysis in R Suitable for R users at all levels, including complete beginners Exercises after each chapter

Theoretical Aspects of Pedigree Analysis

Theoretical Aspects of Pedigree Analysis
Author: Anonim
Publsiher: RAMOT-TEL AVIV UNIVERSITY, ISRAEL
Total Pages: 224
Release: 2006
ISBN 10: 9652744247
ISBN 13: 9789652744241
Language: EN, FR, DE, ES & NL

Theoretical Aspects of Pedigree Analysis Book Review:

Breed Predispositions to Disease in Dogs and Cats

Breed Predispositions to Disease in Dogs and Cats
Author: Alex Gough,Alison Thomas
Publsiher: John Wiley & Sons
Total Pages: 352
Release: 2011-09-26
ISBN 10: 1444359916
ISBN 13: 9781444359916
Language: EN, FR, DE, ES & NL

Breed Predispositions to Disease in Dogs and Cats Book Review:

This unique resource brings together valuable information on breed-related diseases in one quick-reference volume. Divided into one section for dogs and another for cats, inherited and other prevalent disorders are listed breed-by-breed. The final section describes each of the disorders in more detail. All the information is drawn from high-quality sources, including research journals and veterinary texts, with extensive references provided. This invaluable reference helps veterinary professionals to advise clients on their choice of breed and what problems to look out for. Whether you're a veterinarian, geneticist, a breeder, or a pet owner, this fully-referenced book will save you hours of searching through scattered literature.

Sheep and Goat Gene Exploration

Sheep and Goat Gene Exploration
Author: Shaobin Li,Rui Su,Xin Wang
Publsiher: Frontiers Media SA
Total Pages: 135
Release: 2022-04-25
ISBN 10: 288974986X
ISBN 13: 9782889749867
Language: EN, FR, DE, ES & NL

Sheep and Goat Gene Exploration Book Review:

Relationship Inference with Familias and R

Relationship Inference with Familias and R
Author: Thore Egeland,Daniel Kling,Petter Mostad
Publsiher: Academic Press
Total Pages: 256
Release: 2015-12-24
ISBN 10: 012802626X
ISBN 13: 9780128026267
Language: EN, FR, DE, ES & NL

Relationship Inference with Familias and R Book Review:

Relationship Inference in Familias and R discusses the use of Familias and R software to understand genetic kinship of two or more DNA samples. This software is commonly used for forensic cases to establish paternity, identify victims or analyze genetic evidence at crime scenes when kinship is involved. The book explores utilizing Familias software and R packages for difficult situations including inbred families, mutations and missing data from degraded DNA. The book additionally addresses identification following mass disasters, familial searching, non-autosomal marker analysis and relationship inference using linked markers. The second part of the book focuses on more statistical issues such as estimation and uncertainty of model parameters. Although written for use with human DNA, the principles can be applied to non-human genetics for animal pedigrees and/or analysis of plants for agriculture purposes. The book contains necessary tools to evaluate any type of forensic case where kinship is an issue. This volume focuses on the core material and omits most general background material on probability, statistics and forensic genetics Each chapter includes exercises with available solutions The web page familias.name contains supporting material

Book of Abstracts of the 65th Annual Meeting of the European Association for Animal Production

Book of Abstracts of the 65th Annual Meeting of the European Association for Animal Production
Author: EAAP scientific committee
Publsiher: Wageningen Academic Publishers
Total Pages: 486
Release: 2014-08-13
ISBN 10: 9086867995
ISBN 13: 9789086867998
Language: EN, FR, DE, ES & NL

Book of Abstracts of the 65th Annual Meeting of the European Association for Animal Production Book Review:

This Book of Abstracts is the main publication of the 65th Annual Meeting of the European Federation for Animal Science 2014 in Copenhagen, Denmark. It contains abstracts of the invited papers and contributed presentations. The meeting addressed subjects relating to science and innovation. Important problems were also discussed during the sessions of EAAP's nine Commissions: Animal Genetics, Animal Nutrition, Animal Management and Health, Animal Physiology, Cattle Production, Sheep and Goat Production, Pig Production, Horse Production and Livestock Farming Systems.

Novel Approaches to the Analysis of Family Data in Genetic Epidemiology

Novel Approaches to the Analysis of Family Data in Genetic Epidemiology
Author: Xiangqing Sun,Jill S. Barnholtz-Sloan,Nathan Morris,Robert C. Elston
Publsiher: Frontiers Media SA
Total Pages: 135
Release: 2016-08-17
ISBN 10: 2889199320
ISBN 13: 9782889199327
Language: EN, FR, DE, ES & NL

Novel Approaches to the Analysis of Family Data in Genetic Epidemiology Book Review:

Genome-wide association studies (GWAS) for complex disorders with large case-control populations have been performed on hundreds of traits in more than 1200 published studies (http://www.genome.gov/gwastudies/) but the variants detected by GWAS account for little of the heritability of these traits, leading to an increasing interest in using family based designs. While GWAS studies are designed to find common variants with low to moderate attributable risks, family based studies are expected to find rare variants with high attributable risk. Because family-based designs can better control both genetic and environmental background, this study design is robust to heterogeneity and population stratification. Moreover, in family-based analysis, the background genetic variation can be modeled to control the residual variance which could increase the power to identify disease associated rare variants. Analysis of families can also help us gain knowledge about disease transmission and inheritance patterns. Although a family-based design has the advantage of being robust to false positives, novel and powerful methods to analyze families in genetic epidemiology continue to be needed, especially for the interaction between genetic and environmental factors associated with disease. Moreover, with the rapid development of sequencing technology, advances in approaches to the design and analysis of sequencing data in families are also greatly needed. The 11 articles in this book all introduce new methodology and, using family data, substantial new findings are presented in the areas of infectious diseases, diabetes, eye traits, autism spectrum disorder and prostate cancer.

Blackwell s Five Minute Veterinary Consult Ruminant

Blackwell s Five Minute Veterinary Consult  Ruminant
Author: Christopher Chase,Kaitlyn Lutz,Erica McKenzie,Ahmed Tibary
Publsiher: John Wiley & Sons
Total Pages: 1008
Release: 2017-10-23
ISBN 10: 1119064686
ISBN 13: 9781119064688
Language: EN, FR, DE, ES & NL

Blackwell s Five Minute Veterinary Consult Ruminant Book Review:

Blackwell's Five-Minute Veterinary Consult: Ruminant, Second Edition keeps practitioners completely current with the latest in disease management for ruminants and camelids. Updates the first all-in-one ruminant resource designed specifically for quick information retrieval Provides identically formatted topics for easy searching by alphabetical listing or by discipline, with each topic indicating the species affected Offers fast access to the accumulated wisdom of hundreds of veterinary experts Adds more than 100 new topics, with significant revisions to existing topics Includes access to a companion website with additional topics, client education handouts, and figures

An Introduction to Genetic Epidemiology

An Introduction to Genetic Epidemiology
Author: Lyle J. Palmer,George Davey Smith,Paul R. Burton
Publsiher: Policy Press
Total Pages: 230
Release: 2011-05-31
ISBN 10: 1861348975
ISBN 13: 9781861348975
Language: EN, FR, DE, ES & NL

An Introduction to Genetic Epidemiology Book Review:

Genetic epidemiology is a field that has acquired a central role in modern biomedical science. This book provides an introduction to genetic epidemiology that begins with a primer in human molecular genetics and then examines the standard methods in population genetics and genetic epidemiology

Current Developments in Anthropological Genetics

Current Developments in Anthropological Genetics
Author: James H. Mielke
Publsiher: Springer Science & Business Media
Total Pages: 436
Release: 2012-12-06
ISBN 10: 146133084X
ISBN 13: 9781461330844
Language: EN, FR, DE, ES & NL

Current Developments in Anthropological Genetics Book Review:

The papers in this volume were presented as part of the University of Kansas Department of Anthropology Distinguished Lecture Program on Anthro pological Genetics. Consecutively, each contributor spent approximately a week on the campus at Lawrence participating in a seminar. The contributors to this volume were not on campus at one time, but visited us on alternating weeks; hence, a symposium-type interchange was not possible between all participants. However, the students and faculty of Kansas University acted as a sounding board. This volume can be considered a companion and continuation of Methods and Theories of Anthropological Genetics, which was based upon a symposium on the state of the art in 1971. This present volume reflects what we consider to be some of the advances and current developments in anthropological genetics since 1973. Emphasis has shifted, to some degree, away from population struc ture analysis (as depicted in Crawford and Workman) to genetic epidemiology. However, population structure still remains a fertile and ongoing area of research with many theoretical questions still remaining unanswered.

Genetics and the Extinction of Species

Genetics and the Extinction of Species
Author: Laura Landweber,Andrew Dobson
Publsiher: Princeton University Press
Total Pages: 135
Release: 2021-01-12
ISBN 10: 069122403X
ISBN 13: 9780691224039
Language: EN, FR, DE, ES & NL

Genetics and the Extinction of Species Book Review:

Darwin's Origin of Species and Dobzhansky's Genetics and the Origin of Species have been the cornerstones of modern evolutionary and population genetic theory for the past hundred years, but in the twenty-first century, biologists will face graver problems of extinction. In this collection, a team of leading biologists demonstrates why the burgeoning field of conservation biology must continue to rely on the insights of population genetics if we are to preserve the diversity of living species. Technological and theoretical developments throughout the 1990s have allowed for important new insights into how populations have evolved in response to past selection pressures, while providing a broad new understanding of the genetic structure of natural populations. The authors explore these advances and argue for the applicability of new genetic methods in conservation biology. The volume covers such topics as the reasons for extinctions, the best ways to measure biodiversity, and the benefits and drawbacks of policies like captive breeding. Genetics and the Extinction of Species is a rich source of information for biologists and policymakers who want to learn more about the host of tools, theories, and approaches available for conserving biodiversity. In addition to the editors, the contributors to the volume are William Amos, Rebecca Cann, Kathryn Rodriguez-Clark, Leslie Douglas, Leonard Freed, Paul Harvey, Kent Holsinger, Russell Lande, and Helen Steers.

Wild Mammals in Captivity

Wild Mammals in Captivity
Author: Devra G. Kleiman,Katerina V. Thompson,Charlotte Kirk Baer
Publsiher: University of Chicago Press
Total Pages: 720
Release: 2010-08-15
ISBN 10: 0226440117
ISBN 13: 9780226440118
Language: EN, FR, DE, ES & NL

Wild Mammals in Captivity Book Review:

Zoos, aquaria, and wildlife parks are vital centers of animal conservation and management. For nearly fifteen years, these institutions have relied on Wild Mammals in Captivity as the essential reference for their work. Now the book reemerges in a completely updated second edition. Wild Mammals in Captivity presents the most current thinking and practice in the care and management of wild mammals in zoos and other institutions. In one comprehensive volume, the editors have gathered the most current information from studies of animal behavior; advances in captive breeding; research in physiology, genetics, and nutrition; and new thinking in animal management and welfare. In this edition, more than three-quarters of the text is new, and information from more than seventy-five contributors is thoroughly updated. The standard text for all courses in zoo biology, Wild Mammals in Captivity will, in its new incarnation, continue to be used by zoo managers, animal caretakers, researchers, and anyone with an interest in how to manage animals in captive conditions.

Proceedings of the Section on Bayesian Statistical Science

Proceedings of the Section on Bayesian Statistical Science
Author: American Statistical Association. Section on Bayesian Statistical Science
Publsiher: Unknown
Total Pages: 442
Release: 1998
ISBN 10: 1928374650XXX
ISBN 13: UOM:39015054014496
Language: EN, FR, DE, ES & NL

Proceedings of the Section on Bayesian Statistical Science Book Review:

Genetic Factors In Nutrition

Genetic Factors In Nutrition
Author: Hector Bourges
Publsiher: Elsevier
Total Pages: 458
Release: 2012-12-02
ISBN 10: 032314960X
ISBN 13: 9780323149600
Language: EN, FR, DE, ES & NL

Genetic Factors In Nutrition Book Review:

Genetic Factors in Nutrition presents the proceedings of the International Workshop on Genetic Factors in Nutrition, held in Teotihuacan, Mexico, on August 4-8, 1982. The papers explore the link between genetics and nutrition in the context of biological evolution. They provide examples of successful interaction between the two disciplines and consider some aspects of nutrient requirements, as well as utilization and consideration of methodological approaches to evaluate nutritional status, with an emphasis on malnutrition. Divided into six parts encompassing 29 chapters, this volume begins with an overview of genetics and nutrition from an evolutionary perspective, citing findings among Amerindians. It proceeds with a discussion of the potential application of genetic epidemiology in nutritional research, nutrient requirements and metabolism, the association between obesity and energy balance, and assessment of nutritional status. It also presents case studies of the correlation between genetics and nutrition before introducing the reader to genetic inheritance and growth in human groups suffering from chronic under-nutrition. Some data derived from nutrition longitudinal studies are analyzed to interpret the nutrition-genetics interaction. This book will be a valuable source of information for scientists and students in genetics and nutrition.

Hidden Markov Models for Time Series

Hidden Markov Models for Time Series
Author: Walter Zucchini,Iain L. MacDonald,Roland Langrock
Publsiher: CRC Press
Total Pages: 370
Release: 2017-12-19
ISBN 10: 1482253844
ISBN 13: 9781482253849
Language: EN, FR, DE, ES & NL

Hidden Markov Models for Time Series Book Review:

Hidden Markov Models for Time Series: An Introduction Using R, Second Edition illustrates the great flexibility of hidden Markov models (HMMs) as general-purpose models for time series data. The book provides a broad understanding of the models and their uses. After presenting the basic model formulation, the book covers estimation, forecasting, decoding, prediction, model selection, and Bayesian inference for HMMs. Through examples and applications, the authors describe how to extend and generalize the basic model so that it can be applied in a rich variety of situations. The book demonstrates how HMMs can be applied to a wide range of types of time series: continuous-valued, circular, multivariate, binary, bounded and unbounded counts, and categorical observations. It also discusses how to employ the freely available computing environment R to carry out the computations. Features Presents an accessible overview of HMMs Explores a variety of applications in ecology, finance, epidemiology, climatology, and sociology Includes numerous theoretical and programming exercises Provides most of the analysed data sets online New to the second edition A total of five chapters on extensions, including HMMs for longitudinal data, hidden semi-Markov models and models with continuous-valued state process New case studies on animal movement, rainfall occurrence and capture-recapture data

German Medical Data Sciences A Learning Healthcare System

German Medical Data Sciences  A Learning Healthcare System
Author: U. Hübner,U. Sax,H.-U. Prokosch
Publsiher: IOS Press
Total Pages: 260
Release: 2018-09-06
ISBN 10: 1614998965
ISBN 13: 9781614998969
Language: EN, FR, DE, ES & NL

German Medical Data Sciences A Learning Healthcare System Book Review:

Advances in digital and information technology have meant that medical informatics and its associated fields are of ever-increasing importance in the modern healthcare environment. This book presents selected papers from the 63rd annual conference of the German Society of Medical Information Sciences, Biometry, and Epidemiology, GMDS 2018, held in Osnabrück, Germany, in September 2018. The society encompasses not only medical informatics, biometry and epidemiology, but also medical bioinformatics, systems biology and health data management. The title of this year’s conference is “The Learning Health System: Research Based, Innovative, Connecting”, and 38 full papers of the 164 oral presentations and 65 posters delivered at the conference are included here. A wide variety of scientific topics are covered, including standards to enable the interoperable interchange of information; metadata management; record linkage; IT issues for health care networks; interprofessional teaching and training; eHealth legislation; analysis of miRNAs and RNA-Seq data, among others. The contributors are all specialists in their field, and this book disseminates some of the innovative ideas which are urgently needed to meet the challenges facing a constantly developing digital healthcare environment.

Genetic factors in coronary heart disease

Genetic factors in coronary heart disease
Author: U. Goldbourt,U. de Faire,K. Berg
Publsiher: Springer Science & Business Media
Total Pages: 463
Release: 2012-12-06
ISBN 10: 9401111308
ISBN 13: 9789401111300
Language: EN, FR, DE, ES & NL

Genetic factors in coronary heart disease Book Review:

Incidence and mortality of atherosclerosis and coronary heart disease (CHD) vary considerably among races, populations and ethnic groups. Some individuals with low levels of risk factors succumb early to disease while many others with a high risk profile do not. CHD clusters in families and is manyfold increased in first degree relatives of persons with an early onset of the disease. Such studies provide compelling evidence of the high degree of heritability of CHD and its risk factors. This book consolidates the available evidence for the roles of genetics in atherosclerosis, its correlates and its sequelae. It presents and discusses the methodology currently used to elucidate the role of genetics. Separate parts focus on evidence of familial aggregation and ethnic variability of the disease and on monogenic and polygenic inheritance modes including all the recent findings and innovation. The book also contains chapters on the genetic aspects of vessel wall processes, such as early structural findings in histological studies and the variability of coronary anatomic patterns. Polymorphisms at the DNA level (RFLP) are detailed and reviewed. Directions for future research in the exciting and fast developing realm of genetic epidemiology are outlined and the major preventive and public health implications are discussed. Genetic Factors in Coronary Heart Disease provides a systematic review of findings, integrated to offer a comprehensive summary and stepping stone for future research. It will be of interest to investigators in atherosclerosis, genetics, epidemiology, biostatistics, cardiology and public health.

Pedigree Analysis in Human Genetics

Pedigree Analysis in Human Genetics
Author: Elizabeth Alison Thompson
Publsiher: Unknown
Total Pages: 213
Release: 1986
ISBN 10: 1928374650XXX
ISBN 13: UOM:39015009570147
Language: EN, FR, DE, ES & NL

Pedigree Analysis in Human Genetics Book Review:

Economic Analysis of Diversity in Modern Wheat

Economic Analysis of Diversity in Modern Wheat
Author: Erika C.H. Meng
Publsiher: CRC Press
Total Pages: 204
Release: 2019-04-23
ISBN 10: 0429526679
ISBN 13: 9780429526671
Language: EN, FR, DE, ES & NL

Economic Analysis of Diversity in Modern Wheat Book Review:

Scientific breeding in the twentieth century greatly accelerated wheat`s evolution, producing high-yielding varieties that helped avoid famine in many developing countries. Emerging scientific tools hold promise for identifying and tapping new, useful genetic diversity within wheat`s primary and secondary gene pools and, through genetic engineering, beyond.The book describes generally how policies affect wheat genetic diversity; it looks at historical changes in wheat genetic diversity, as policy and priorities have evolved; it identifies factors that explain changes and differences in spatial diversity; and finally, it analyzes the productivity impacts of changes in diversity. Chapters define various types of crop genetic diversity and ways to measure them, framing the definitions and metrics in the contexts for which they are most relevant.

Genetic Basis of the Epilepsies

Genetic Basis of the Epilepsies
Author: Victor Elving Anderson
Publsiher: Raven Press (ID)
Total Pages: 380
Release: 1982
ISBN 10: 1928374650XXX
ISBN 13: UOM:39015003803619
Language: EN, FR, DE, ES & NL

Genetic Basis of the Epilepsies Book Review: