Pedigree Analysis in R

Pedigree Analysis in R
Author: Magnus Dehli Vigeland
Publsiher: Academic Press
Total Pages: 184
Release: 2021-05-06
ISBN 10: 0128245603
ISBN 13: 9780128245606
Language: EN, FR, DE, ES & NL

Pedigree Analysis in R Book Review:

Pedigree Analysis in R gives an introduction to the theory of relatedness and covers a range of applications in forensic and medical genetics. The book's material was developed through teaching courses on genetic relatedness, pedigree analysis and R, and offers insights from a decade of research activities in forensic and medical genetics. The R code in the book uses the ped suite, a unified collection of packages for pedigree analysis, developed by the author. All code examples are given in full, allowing accurate reproduction of figures and results. At the end of each chapter, a selection of exercises encourages the reader to explore further and perform their own analyses. Introduction to the theory of genetic relatedness, richly illustrated with classic and novel examples In-depth case studies including kinship testing, pedigree reconstruction, linkage analysis and clinical segregation analysis Easy-to-follow R code with explanations Based on the ped suite packages for pedigree analysis in R Suitable for R users at all levels, including complete beginners Exercises after each chapter

Relationship Inference with Familias and R

Relationship Inference with Familias and R
Author: Thore Egeland,Daniel Kling,Petter Mostad
Publsiher: Academic Press
Total Pages: 256
Release: 2015-12-24
ISBN 10: 012802626X
ISBN 13: 9780128026267
Language: EN, FR, DE, ES & NL

Relationship Inference with Familias and R Book Review:

Relationship Inference in Familias and R discusses the use of Familias and R software to understand genetic kinship of two or more DNA samples. This software is commonly used for forensic cases to establish paternity, identify victims or analyze genetic evidence at crime scenes when kinship is involved. The book explores utilizing Familias software and R packages for difficult situations including inbred families, mutations and missing data from degraded DNA. The book additionally addresses identification following mass disasters, familial searching, non-autosomal marker analysis and relationship inference using linked markers. The second part of the book focuses on more statistical issues such as estimation and uncertainty of model parameters. Although written for use with human DNA, the principles can be applied to non-human genetics for animal pedigrees and/or analysis of plants for agriculture purposes. The book contains necessary tools to evaluate any type of forensic case where kinship is an issue. This volume focuses on the core material and omits most general background material on probability, statistics and forensic genetics Each chapter includes exercises with available solutions The web page familias.name contains supporting material

Breed Predispositions to Disease in Dogs and Cats

Breed Predispositions to Disease in Dogs and Cats
Author: Alex Gough,Alison Thomas
Publsiher: John Wiley & Sons
Total Pages: 352
Release: 2011-09-26
ISBN 10: 1444359916
ISBN 13: 9781444359916
Language: EN, FR, DE, ES & NL

Breed Predispositions to Disease in Dogs and Cats Book Review:

This unique resource brings together valuable information on breed-related diseases in one quick-reference volume. Divided into one section for dogs and another for cats, inherited and other prevalent disorders are listed breed-by-breed. The final section describes each of the disorders in more detail. All the information is drawn from high-quality sources, including research journals and veterinary texts, with extensive references provided. This invaluable reference helps veterinary professionals to advise clients on their choice of breed and what problems to look out for. Whether you're a veterinarian, geneticist, a breeder, or a pet owner, this fully-referenced book will save you hours of searching through scattered literature.

Sheep and Goat Gene Exploration

Sheep and Goat Gene Exploration
Author: Shaobin Li,Rui Su,Xin Wang
Publsiher: Frontiers Media SA
Total Pages: 135
Release: 2022-04-25
ISBN 10: 288974986X
ISBN 13: 9782889749867
Language: EN, FR, DE, ES & NL

Sheep and Goat Gene Exploration Book Review:

An Introduction to Genetic Epidemiology

An Introduction to Genetic Epidemiology
Author: Lyle J. Palmer,George Davey Smith,Paul R. Burton
Publsiher: Policy Press
Total Pages: 230
Release: 2011-05-31
ISBN 10: 1861348975
ISBN 13: 9781861348975
Language: EN, FR, DE, ES & NL

An Introduction to Genetic Epidemiology Book Review:

Genetic epidemiology is a field that has acquired a central role in modern biomedical science. This book provides an introduction to genetic epidemiology that begins with a primer in human molecular genetics and then examines the standard methods in population genetics and genetic epidemiology

Current Developments in Anthropological Genetics

Current Developments in Anthropological Genetics
Author: James H. Mielke
Publsiher: Springer Science & Business Media
Total Pages: 436
Release: 2012-12-06
ISBN 10: 146133084X
ISBN 13: 9781461330844
Language: EN, FR, DE, ES & NL

Current Developments in Anthropological Genetics Book Review:

The papers in this volume were presented as part of the University of Kansas Department of Anthropology Distinguished Lecture Program on Anthro pological Genetics. Consecutively, each contributor spent approximately a week on the campus at Lawrence participating in a seminar. The contributors to this volume were not on campus at one time, but visited us on alternating weeks; hence, a symposium-type interchange was not possible between all participants. However, the students and faculty of Kansas University acted as a sounding board. This volume can be considered a companion and continuation of Methods and Theories of Anthropological Genetics, which was based upon a symposium on the state of the art in 1971. This present volume reflects what we consider to be some of the advances and current developments in anthropological genetics since 1973. Emphasis has shifted, to some degree, away from population struc ture analysis (as depicted in Crawford and Workman) to genetic epidemiology. However, population structure still remains a fertile and ongoing area of research with many theoretical questions still remaining unanswered.

Genetics and the Extinction of Species

Genetics and the Extinction of Species
Author: Laura Landweber,Andrew Dobson
Publsiher: Princeton University Press
Total Pages: 135
Release: 2021-01-12
ISBN 10: 069122403X
ISBN 13: 9780691224039
Language: EN, FR, DE, ES & NL

Genetics and the Extinction of Species Book Review:

Darwin's Origin of Species and Dobzhansky's Genetics and the Origin of Species have been the cornerstones of modern evolutionary and population genetic theory for the past hundred years, but in the twenty-first century, biologists will face graver problems of extinction. In this collection, a team of leading biologists demonstrates why the burgeoning field of conservation biology must continue to rely on the insights of population genetics if we are to preserve the diversity of living species. Technological and theoretical developments throughout the 1990s have allowed for important new insights into how populations have evolved in response to past selection pressures, while providing a broad new understanding of the genetic structure of natural populations. The authors explore these advances and argue for the applicability of new genetic methods in conservation biology. The volume covers such topics as the reasons for extinctions, the best ways to measure biodiversity, and the benefits and drawbacks of policies like captive breeding. Genetics and the Extinction of Species is a rich source of information for biologists and policymakers who want to learn more about the host of tools, theories, and approaches available for conserving biodiversity. In addition to the editors, the contributors to the volume are William Amos, Rebecca Cann, Kathryn Rodriguez-Clark, Leslie Douglas, Leonard Freed, Paul Harvey, Kent Holsinger, Russell Lande, and Helen Steers.

American Journal of Medical Genetics

American Journal of Medical Genetics
Author: Anonim
Publsiher: Unknown
Total Pages: 135
Release: 1984
ISBN 10: 1928374650XXX
ISBN 13: UCAL:B3529710
Language: EN, FR, DE, ES & NL

American Journal of Medical Genetics Book Review:

Genealogical Genetic Structure

Genealogical Genetic Structure
Author: C. Cannings
Publsiher: Cambridge University Press
Total Pages: 163
Release: 1981-11-26
ISBN 10: 9780521239462
ISBN 13: 052123946X
Language: EN, FR, DE, ES & NL

Genealogical Genetic Structure Book Review:

Although the long-term processes of evolution are selection and mutation, the infrastructure of a population is a no less important force in determining the distributions of genetic characteristics observable within populations. In small populations, and in particular in human populations, complex patterns of genealogical relationship between individuals can be an important factor in the maintenance of genetic variability. The aim of this book is to develop the quantitative theory of the interrelationship between the genealogical and the genetic structures of a population. Aspects of other structural features, such as migration patterns, are also discussed, but are not central to the development. There are three major aspects; each comprises two chapters of the text. First, genealogical relationships are characterized in a way which can illuminate their genetic consequences. Second, the evolutionary aspects of genealogical structure are developed. Finally, the last two chapters present methods of characterizing the complete structure of a genealogy, and of computing relevant parameters of genealogical structure; these topics are of relevance to genetic epidemiology as well as to population genetics.

Wild Mammals in Captivity

Wild Mammals in Captivity
Author: Devra G. Kleiman,Katerina V. Thompson,Charlotte Kirk Baer
Publsiher: University of Chicago Press
Total Pages: 720
Release: 2010-08-15
ISBN 10: 0226440117
ISBN 13: 9780226440118
Language: EN, FR, DE, ES & NL

Wild Mammals in Captivity Book Review:

Zoos, aquaria, and wildlife parks are vital centers of animal conservation and management. For nearly fifteen years, these institutions have relied on Wild Mammals in Captivity as the essential reference for their work. Now the book reemerges in a completely updated second edition. Wild Mammals in Captivity presents the most current thinking and practice in the care and management of wild mammals in zoos and other institutions. In one comprehensive volume, the editors have gathered the most current information from studies of animal behavior; advances in captive breeding; research in physiology, genetics, and nutrition; and new thinking in animal management and welfare. In this edition, more than three-quarters of the text is new, and information from more than seventy-five contributors is thoroughly updated. The standard text for all courses in zoo biology, Wild Mammals in Captivity will, in its new incarnation, continue to be used by zoo managers, animal caretakers, researchers, and anyone with an interest in how to manage animals in captive conditions.

Theoretical Aspects of Pedigree Analysis

Theoretical Aspects of Pedigree Analysis
Author: Anonim
Publsiher: RAMOT-TEL AVIV UNIVERSITY, ISRAEL
Total Pages: 224
Release: 2006
ISBN 10: 9652744247
ISBN 13: 9789652744241
Language: EN, FR, DE, ES & NL

Theoretical Aspects of Pedigree Analysis Book Review:

Proceedings of the Section on Bayesian Statistical Science

Proceedings of the Section on Bayesian Statistical Science
Author: American Statistical Association. Section on Bayesian Statistical Science
Publsiher: Unknown
Total Pages: 135
Release: 1998
ISBN 10: 1928374650XXX
ISBN 13: UOM:39015054014496
Language: EN, FR, DE, ES & NL

Proceedings of the Section on Bayesian Statistical Science Book Review:

Mathematical and Statistical Methods for Genetic Analysis

Mathematical and Statistical Methods for Genetic Analysis
Author: Kenneth Lange
Publsiher: Springer Science & Business Media
Total Pages: 265
Release: 2013-04-17
ISBN 10: 1475727399
ISBN 13: 9781475727395
Language: EN, FR, DE, ES & NL

Mathematical and Statistical Methods for Genetic Analysis Book Review:

Geneticists now stand on the threshold of sequencing the genome in its entirety. The unprecedented insights into human disease and evolution offered by mapping and sequencing are transforming medicine and agriculture. This revolution depends vitally on the contributions made by applied mathematicians, statisticians, and computer scientists. Kenneth Lange has written a book to enable graduate students in the mathematical sciences to understand and model the epidemiological and experimental data encountered in genetics research. Mathematical, statistical, and computational principles relevant to this task are developed hand-in-hand with applications to gene mapping, risk prediction, and the testing of epidemiological hypotheses. The book covers many topics previously only accessible in journal articles, such as pedigree analysis algorithms, Markov chain, Monte Carlo methods, reconstruction of evolutionary trees, radiation hybrid mapping, and models of recombination. The whole is backed by numerous exercise sets.

Genetic Factors In Nutrition

Genetic Factors In Nutrition
Author: Hector Bourges
Publsiher: Elsevier
Total Pages: 458
Release: 2012-12-02
ISBN 10: 032314960X
ISBN 13: 9780323149600
Language: EN, FR, DE, ES & NL

Genetic Factors In Nutrition Book Review:

Genetic Factors in Nutrition presents the proceedings of the International Workshop on Genetic Factors in Nutrition, held in Teotihuacan, Mexico, on August 4-8, 1982. The papers explore the link between genetics and nutrition in the context of biological evolution. They provide examples of successful interaction between the two disciplines and consider some aspects of nutrient requirements, as well as utilization and consideration of methodological approaches to evaluate nutritional status, with an emphasis on malnutrition. Divided into six parts encompassing 29 chapters, this volume begins with an overview of genetics and nutrition from an evolutionary perspective, citing findings among Amerindians. It proceeds with a discussion of the potential application of genetic epidemiology in nutritional research, nutrient requirements and metabolism, the association between obesity and energy balance, and assessment of nutritional status. It also presents case studies of the correlation between genetics and nutrition before introducing the reader to genetic inheritance and growth in human groups suffering from chronic under-nutrition. Some data derived from nutrition longitudinal studies are analyzed to interpret the nutrition-genetics interaction. This book will be a valuable source of information for scientists and students in genetics and nutrition.

Genotype to Phenotype

Genotype to Phenotype
Author: J. J. Goodship,S. Malcolm
Publsiher: Garland Science
Total Pages: 312
Release: 2003-12-16
ISBN 10: 1135322929
ISBN 13: 9781135322922
Language: EN, FR, DE, ES & NL

Genotype to Phenotype Book Review:

This new edition builds on the success of the first by reviewing the increased understanding of the mechanisms of gene action in humans, focusing particularly on those derived from the study of genetic diseases. It deals mainly with the fundamental aspects of gene arrangement and expression rather than mutation. As well as updating and revising material from the first edition, it covers methods of exploring gene function and contains a range of chapters on specific systems which raise issues of special interest such as imprinting or homologous genes within clusters.

Hidden Markov Models for Time Series

Hidden Markov Models for Time Series
Author: Walter Zucchini,Iain L. MacDonald,Roland Langrock
Publsiher: CRC Press
Total Pages: 370
Release: 2017-12-19
ISBN 10: 1482253844
ISBN 13: 9781482253849
Language: EN, FR, DE, ES & NL

Hidden Markov Models for Time Series Book Review:

Hidden Markov Models for Time Series: An Introduction Using R, Second Edition illustrates the great flexibility of hidden Markov models (HMMs) as general-purpose models for time series data. The book provides a broad understanding of the models and their uses. After presenting the basic model formulation, the book covers estimation, forecasting, decoding, prediction, model selection, and Bayesian inference for HMMs. Through examples and applications, the authors describe how to extend and generalize the basic model so that it can be applied in a rich variety of situations. The book demonstrates how HMMs can be applied to a wide range of types of time series: continuous-valued, circular, multivariate, binary, bounded and unbounded counts, and categorical observations. It also discusses how to employ the freely available computing environment R to carry out the computations. Features Presents an accessible overview of HMMs Explores a variety of applications in ecology, finance, epidemiology, climatology, and sociology Includes numerous theoretical and programming exercises Provides most of the analysed data sets online New to the second edition A total of five chapters on extensions, including HMMs for longitudinal data, hidden semi-Markov models and models with continuous-valued state process New case studies on animal movement, rainfall occurrence and capture-recapture data

German Medical Data Sciences A Learning Healthcare System

German Medical Data Sciences  A Learning Healthcare System
Author: U. Hübner,U. Sax,H.-U. Prokosch
Publsiher: IOS Press
Total Pages: 260
Release: 2018-09-06
ISBN 10: 1614998965
ISBN 13: 9781614998969
Language: EN, FR, DE, ES & NL

German Medical Data Sciences A Learning Healthcare System Book Review:

Advances in digital and information technology have meant that medical informatics and its associated fields are of ever-increasing importance in the modern healthcare environment. This book presents selected papers from the 63rd annual conference of the German Society of Medical Information Sciences, Biometry, and Epidemiology, GMDS 2018, held in Osnabrück, Germany, in September 2018. The society encompasses not only medical informatics, biometry and epidemiology, but also medical bioinformatics, systems biology and health data management. The title of this year’s conference is “The Learning Health System: Research Based, Innovative, Connecting”, and 38 full papers of the 164 oral presentations and 65 posters delivered at the conference are included here. A wide variety of scientific topics are covered, including standards to enable the interoperable interchange of information; metadata management; record linkage; IT issues for health care networks; interprofessional teaching and training; eHealth legislation; analysis of miRNAs and RNA-Seq data, among others. The contributors are all specialists in their field, and this book disseminates some of the innovative ideas which are urgently needed to meet the challenges facing a constantly developing digital healthcare environment.

Genetic factors in coronary heart disease

Genetic factors in coronary heart disease
Author: U. Goldbourt,U. de Faire,K. Berg
Publsiher: Springer Science & Business Media
Total Pages: 463
Release: 2012-12-06
ISBN 10: 9401111308
ISBN 13: 9789401111300
Language: EN, FR, DE, ES & NL

Genetic factors in coronary heart disease Book Review:

Incidence and mortality of atherosclerosis and coronary heart disease (CHD) vary considerably among races, populations and ethnic groups. Some individuals with low levels of risk factors succumb early to disease while many others with a high risk profile do not. CHD clusters in families and is manyfold increased in first degree relatives of persons with an early onset of the disease. Such studies provide compelling evidence of the high degree of heritability of CHD and its risk factors. This book consolidates the available evidence for the roles of genetics in atherosclerosis, its correlates and its sequelae. It presents and discusses the methodology currently used to elucidate the role of genetics. Separate parts focus on evidence of familial aggregation and ethnic variability of the disease and on monogenic and polygenic inheritance modes including all the recent findings and innovation. The book also contains chapters on the genetic aspects of vessel wall processes, such as early structural findings in histological studies and the variability of coronary anatomic patterns. Polymorphisms at the DNA level (RFLP) are detailed and reviewed. Directions for future research in the exciting and fast developing realm of genetic epidemiology are outlined and the major preventive and public health implications are discussed. Genetic Factors in Coronary Heart Disease provides a systematic review of findings, integrated to offer a comprehensive summary and stepping stone for future research. It will be of interest to investigators in atherosclerosis, genetics, epidemiology, biostatistics, cardiology and public health.

Clinical Obstetrics

Clinical Obstetrics
Author: E. Albert Reece, MD, PhD, MBA,John C. Hobbins
Publsiher: John Wiley & Sons
Total Pages: 1560
Release: 2008-04-15
ISBN 10: 1405171839
ISBN 13: 9781405171830
Language: EN, FR, DE, ES & NL

Clinical Obstetrics Book Review:

Highly Commended in the Obstetrics and Gynaecology category atthe British Medical Association Book Awards 2008 The third edition of Clinical Obstetrics - The Fetus andMother is unique in that it gives in-depth attention to the twopatients – fetus and mother, giving special coverage to eachpatient. Clinical Obstetrics - The Fetus and Mother coversthe biology, pathology, and clinical management of disordersaffecting the fetus and the mother with illustrations highlightingessential diagnostic features and treatment procedures. The bookhas been extensively revised and in some cases reorganized forclarity and flow. This book is fully up to date with specialchapters on; first trimester prenatal screening 3-D and 4-D ultrasound medical and surgical fetal therapy foetal stem cell therapy prenatal diagnosis and fetal developmental biology benign tumors in pregnancy and extensive discussion of each of the main areas of maternaldiseases. The book has been made more succinct yet heavilyannotated and illustrated giving greater clinical emphasis enablingfast decisions at the point of care; all chapters now have keysummary points making it easy to retrieve information. In addition Clinical Obstetrics - The Fetus and Motherincludes a new searchable CD of the text including over 100 colourillustrations, and a Q&A book allowing you to test yourlearning. Formerly known as Medicine of the Fetus and Mother and highlysuccessful in two previous editions published by Lippincott

Blackwell s Five Minute Veterinary Consult

Blackwell s Five Minute Veterinary Consult
Author: Scott R. R. Haskell
Publsiher: John Wiley & Sons
Total Pages: 1048
Release: 2011-08-24
ISBN 10: 047096118X
ISBN 13: 9780470961186
Language: EN, FR, DE, ES & NL

Blackwell s Five Minute Veterinary Consult Book Review:

The most trusted and well-known quick-reference resource available to veterinarians, Blackwell’s Five-Minute Veterinary Consult series includes this volume on ruminants. Hundreds of top specialists provide coverage of 420 topics arranged alphabetically from A-Z for efficient searching, with each topic indicating the species affected. An accompanying CD includes an additional 175 topics covering management, husbandry, reproduction, and diagnostics. Whether you’re a student or a practicing veterinarian, this reference book will cut down on the time spent navigating through other resources, allowing you to study, diagnose and treat more quickly.