Regulation of B Cell Responses by Non canonical Autophagy

Regulation of B Cell Responses by Non canonical Autophagy
Author: Paula Maldonado Villavicencio
Publsiher: Unknown
Total Pages: 135
Release: 2019
ISBN 10: 1928374650XXX
ISBN 13: OCLC:1197752180
Language: EN, FR, DE, ES & NL

Regulation of B Cell Responses by Non canonical Autophagy Book Review:

Non Canonical Autophagy

Non Canonical Autophagy
Author: Giulia Petroni,Lorenzo Galluzzi
Publsiher: Academic Press
Total Pages: 182
Release: 2021-05-01
ISBN 10: 0128209119
ISBN 13: 9780128209110
Language: EN, FR, DE, ES & NL

Non Canonical Autophagy Book Review:

Non-canonical Autophagy: Mechanisms and Pathophysiological Implications outlines the differences between ‘canonical’ and ‘non-canonical’ forms of autophagy, highlighting the discoveries concerning the molecular mechanisms underlying these unconventional forms of autophagy and the advancements in pathophysiological features of ‘non-canonical’ autophagy. The book discusses all forms of ‘non-canonical’ autophagy and the complexity of autophagy-dependent cell death. Readers will gain a better understanding of mechanisms underlying ‘non-canonical’ autophagy so that they can interpret the biological effects of autophagy correctly and identify reliable, novel and effective treatment strategies. Presents the most advanced information surrounding the molecular mechanisms underlying non-canonical autophagy Outlines the increasing evidence regarding the involvement of non-canonical autophagy in multiple physiological and pathological processes Discusses the therapeutic potential of autophagy modulators and the obstacles that have limited their development

A Study on Non canonical Autophagy Signalling

A Study on Non canonical Autophagy Signalling
Author: Cansu Karabiyik
Publsiher: Unknown
Total Pages: 135
Release: 2021
ISBN 10: 1928374650XXX
ISBN 13: OCLC:1259539942
Language: EN, FR, DE, ES & NL

A Study on Non canonical Autophagy Signalling Book Review:

ATG8 Regulation and Function in Non canonical Autophagy

ATG8 Regulation and Function in Non canonical Autophagy
Author: Katherine Sloan
Publsiher: Unknown
Total Pages: 135
Release: 2020
ISBN 10: 1928374650XXX
ISBN 13: OCLC:1259549236
Language: EN, FR, DE, ES & NL

ATG8 Regulation and Function in Non canonical Autophagy Book Review:

Canonical and Non canonical Autophagy Modulation in Human Primary Macrophages and Its Effect on the Adaptive Immune System

Canonical and Non canonical Autophagy Modulation in Human Primary Macrophages and Its Effect on the Adaptive Immune System
Author: Rebecca Bohn
Publsiher: Unknown
Total Pages: 135
Release: 2017
ISBN 10: 1928374650XXX
ISBN 13: OCLC:987368480
Language: EN, FR, DE, ES & NL

Canonical and Non canonical Autophagy Modulation in Human Primary Macrophages and Its Effect on the Adaptive Immune System Book Review:

Novel Mechanisms of Atg16L1 Recruitment in Non canonical Autophagy

Novel Mechanisms of Atg16L1 Recruitment in Non canonical Autophagy
Author: Katherine Anne Fletcher
Publsiher: Unknown
Total Pages: 135
Release: 2019
ISBN 10: 1928374650XXX
ISBN 13: OCLC:1104602716
Language: EN, FR, DE, ES & NL

Novel Mechanisms of Atg16L1 Recruitment in Non canonical Autophagy Book Review:

Membrane Biogenesis

Membrane Biogenesis
Author: Jos A.F. Op den Kamp
Publsiher: Springer Science & Business Media
Total Pages: 477
Release: 2013-06-29
ISBN 10: 3642731848
ISBN 13: 9783642731846
Language: EN, FR, DE, ES & NL

Membrane Biogenesis Book Review:

Many individual aspects of the dynamics and assembly of biological membranes have been studied in great detail. Cell biological approaches, advanced genetics, biophysics and biochemistry have greatly contributed to an increase in our knowledge in this field.lt is obvious however, that the three major membrane constituents - lipids, proteins and carbohydrates- are studied, in most cases separately and that a coherent overview of the various aspects of membrane biogenesis is not readily available. The NATO Advanced Study Institute on "New Perspectives in the Dynamics of Assembly of Biomembranes" intended to provide such an overview: it was set up to teach students and specialists the achievements obtained in the various research areas and to try and integrate the numerous aspects of membrane assembly into a coherent framework. The articles in here reflect this. Statting with detailed contributions on phospholipid structure, dynamics, organization and biogenesis, an up to date overview of the basic, lipidic backbone of biomembranes is given. Extensive progress is made in the research on membrane protein biosynthesis. In particular the post- and co-translational modification processes of proteins, the mechanisms of protein translocation and the sorting mechanisms which are necessary to direct proteins to their final, intra - or extracellular destination have been characterized in detail. Modern genetic approaches were indispensable in this research area: gene cloning, hybrid protein construction, site directed mutagenesis and sequencing techniques elucidated many functional aspects of specific nucleic acid and amino acid sequences.

Examining the Role of Autophagy in Osteoclast Function

Examining the Role of Autophagy in Osteoclast Function
Author: Anh Nhi Tran
Publsiher: Unknown
Total Pages: 135
Release: 2018
ISBN 10: 1928374650XXX
ISBN 13: OCLC:1064654562
Language: EN, FR, DE, ES & NL

Examining the Role of Autophagy in Osteoclast Function Book Review:

Non canonical Functions on the Essential Autophagy Protein ATG5 in Antigen Processing and Presentation

Non canonical Functions on the Essential Autophagy Protein ATG5 in Antigen Processing and Presentation
Author: Christian Wolfgang Keller
Publsiher: Unknown
Total Pages: 135
Release: 2017
ISBN 10: 1928374650XXX
ISBN 13: OCLC:1004342411
Language: EN, FR, DE, ES & NL

Non canonical Functions on the Essential Autophagy Protein ATG5 in Antigen Processing and Presentation Book Review:

The Non canonical Role of Autophagy Components in the Secretion of Neural Peptide Hormones

The Non canonical Role of Autophagy Components in the Secretion of Neural Peptide Hormones
Author: Anonim
Publsiher: Unknown
Total Pages: 47
Release: 2016
ISBN 10: 1928374650XXX
ISBN 13: OCLC:976434208
Language: EN, FR, DE, ES & NL

The Non canonical Role of Autophagy Components in the Secretion of Neural Peptide Hormones Book Review:

The canonical autophagy pathway has primarily been described as a degradative mechanism, which clears the cell of old damaged organelles, protein aggregates and pathogens. Central to the pathway is the de novo formation of a vesicle structure called the autophagosome, which fuses with lysosomes to degrade its content. The Atg8a/MAP1-LC3 protein family is essential for the formation of the autophagosome, and Atg8a mutations result in a variety of defects related to decreased autophagic function. Recently, we have observed a phenotype in Atg8a mutant Drosophila that is consistent with secretory defects of the peptide hormone Bursicon, which is responsible for wing expansion and cuticle hardening upon eclosion. This observation is in accordance with other recent findings which show that components of the autophagy pathway are also involved in the secretion of bioactive molecules. However, the intersection of autophagy and secretory pathways is not yet fully understood. Here, we show that along with Bursicon two additional peptide hormones are differentially secreted and show impaired hemolymph profiles when autophagic function is lowered in the fly nervous system. This includes the release of the pigment dispersing factor (PDF, circadian cycle) and the mesencephalic astrocyte-derived neurotrophic factor (dMANF, stress response), which is highlighted by the aberrant sleep-circadian behaviors (PDF) and trauma-mediated sensitivity (MANF) associated with Atg8a1 mutant flies. Based on the Bursicon wing phenotype, we conducted a secretion-based screen using the GAL4/UAS-dsRNAi knockdown system and identified Atg8a and other autophagy components involved with organelle initiation and membrane expansion that show impaired Bursicon release upon knockdown. Furthermore, this did not include genes involved with selective autophagy (aggrephagy) or endosomal-lysosomal trafficking. Findings from this research will have broad implications toward understanding complex secretory defects and the intersection of autophagy with other vesicle trafficking pathways.

Autophagy in Health and Disease

Autophagy in Health and Disease
Author: Roberta A. Gottlieb
Publsiher: Academic Press
Total Pages: 227
Release: 2012-10-16
ISBN 10: 0123851017
ISBN 13: 9780123851017
Language: EN, FR, DE, ES & NL

Autophagy in Health and Disease Book Review:

Autophagy in Health and Disease offers an overview of the latest research in autophagy with a translational emphasis. This publication takes scientific research in autophagy a step further and offers integrated content with advancements in autophagy from cell biology and biochemical research to clinical treatments. A necessary reference for the bookshelf of medical and scientific researchers and students, Autophagy in Health and Disease presents high quality, reputable information on autophagy, allowing the reader quick access to the most applicable information. Discusses current understanding of the roles of autophagy in health and disease Covers the background of autophagy, the development of tools and therapeutics to measure and modulate autophagy, and autophagy in tissues and disease processes Features an accompanying website with figures and tables

Autophagy in Autoimmunity

Autophagy in Autoimmunity
Author: Xu-jie Zhou,Panayotis Verginis,Jennifer Martinez,Marko Radic
Publsiher: Frontiers Media SA
Total Pages: 161
Release: 2019-05-15
ISBN 10: 2889458121
ISBN 13: 9782889458127
Language: EN, FR, DE, ES & NL

Autophagy in Autoimmunity Book Review:

Autophagy of the Nervous System

Autophagy of the Nervous System
Author: Zhenyu Yue,Charleen T. Chu
Publsiher: World Scientific
Total Pages: 426
Release: 2012
ISBN 10: 9814350443
ISBN 13: 9789814350440
Language: EN, FR, DE, ES & NL

Autophagy of the Nervous System Book Review:

What is autophagy? Why would neurons or other brain cells digest parts of themselves through autophagy? How can autophagy save the lives of cells under some conditions, but act as a culprit or accomplice to cell death in others? How does dysfunction of autophagy contribute to neurological diseases and can it be repaired or restored? This book addresses these questions and provide an expert view of the emerging concepts in autophagy research, focusing on autophagic processes and regulation in neurons. Current experimental evidence for both evolutionarily conserved and specialized regulatory mechanisms for autophagy in the mammalian nervous system will be presented. Advances in our understanding of the complex interplay of autophagy induction and downregulation will be discussed in relation to the critical balance needed to modulate neuroprotection versus neurodegeneration in the context of neurological diseases including Alzheimer's, Parkinson's, Huntington's, ischemic-hypoxic and lysosomal diseases.

The Autophagy Pathway Bacterial Pathogen Immunity and Evasion

The Autophagy Pathway  Bacterial Pathogen Immunity and Evasion
Author: Chinnaswamy Jagannath,Jere W. McBride,Isabelle Vergne
Publsiher: Frontiers Media SA
Total Pages: 135
Release: 2021-11-25
ISBN 10: 2889716856
ISBN 13: 9782889716852
Language: EN, FR, DE, ES & NL

The Autophagy Pathway Bacterial Pathogen Immunity and Evasion Book Review:

The Role of Immunometabolism in Autoimmune Mediated and Autoinflammatory Disorders

The Role of Immunometabolism in Autoimmune Mediated and Autoinflammatory Disorders
Author: Valentina Pucino,Monica Guma
Publsiher: Frontiers Media SA
Total Pages: 135
Release: 2021-10-14
ISBN 10: 2889714942
ISBN 13: 9782889714940
Language: EN, FR, DE, ES & NL

The Role of Immunometabolism in Autoimmune Mediated and Autoinflammatory Disorders Book Review:

Programmed Cell Death 2 0 The Quality of Cell Death

Programmed Cell Death 2 0  The Quality of Cell Death
Author: Michael Thomas Lotze,Yinan Gong,Jennifer Martinez,Na Dong
Publsiher: Frontiers Media SA
Total Pages: 135
Release: 2022-02-14
ISBN 10: 288974390X
ISBN 13: 9782889743902
Language: EN, FR, DE, ES & NL

Programmed Cell Death 2 0 The Quality of Cell Death Book Review:

Transport Proteins

Transport Proteins
Author: Anonim
Publsiher: Academic Press
Total Pages: 286
Release: 2021-01-21
ISBN 10: 0128220880
ISBN 13: 9780128220887
Language: EN, FR, DE, ES & NL

Transport Proteins Book Review:

Transport Proteins, Volume 123, provides the latest information on the two major groups of transport proteins, those that carry molecules to different locations within a cell or organism and those that carry molecules across otherwise impermeable membranes. Chapters in the updated release include Biology of Iron Transport: Ferroportin, Transport of transition metals across biological membranes, The effect of sport and physical activity on transport proteins: implications for cancer prevention and control, Structural rearrangement in polyketide synthase for improvement its bio-physicochemical properties, Autophagy Proteins and its Homeostasis in Cellular Environment, and much more. Integrates experimental and computational methods for studying the structure and function of transport proteins and their implication in drug design Contains timely chapters written by well-renowned authorities in their field Includes a high number of top quality illustrations, figures and tables, and targets a very wide audience of specialists, researchers and students

Autophagy in Infection and Immunity

Autophagy in Infection and Immunity
Author: Beth Levine,Tamotsu Yoshimori,Vojo Deretic
Publsiher: Springer Science & Business Media
Total Pages: 339
Release: 2009-10-03
ISBN 10: 9783642003028
ISBN 13: 3642003028
Language: EN, FR, DE, ES & NL

Autophagy in Infection and Immunity Book Review:

Autophagy is a fundamental biological process that enables cells to autodigest their own cytosol during starvation and other forms of stress. It has a growing spectrum of acknowledged roles in immunity, aging, development, neurodegeneration, and cancer biology. An immunological role of autophagy was first recognized with the discovery of autophagy’s ability to sanitize the cellular interior by killing intracellular microbes. Since then, the repertoire of autophagy’s roles in immunity has been vastly expanded to include a diverse but interconnected portfolio of regulatory and effector functions. Autophagy is an effector of Th1/Th2 polarization; it fuels MHC II presentation of cytosolic (self and microbial) antigens; it shapes central tolerance; it affects B and T cell homeostasis; it acts both as an effector and a regulator of Toll-like receptor and other innate immunity receptor signaling; and it may help ward off chronic inflammatory disease in humans. With such a multitude of innate and adaptive immunity functions, the study of autophagy in immunity is one of the most rapidly growing fields of contemporary immunological research. This book introduces the reader to the fundamentals of autophagy, guides a novice and the well-informed reader alike through different immunological aspects of autophagy as well as the countermeasures used by highly adapted pathogens to fight autophagy, and provides the expert with the latest, up-to-date information on the specifics of the leading edge of autophagy research in infection and immunity.

Novel Cancer Treatments based on Autophagy Modulation

Novel Cancer Treatments based on Autophagy Modulation
Author: Marco Cordani,Álvaro Somoza,Marco Tafani,Ilaria Dando,Suresh Kumar
Publsiher: Frontiers Media SA
Total Pages: 135
Release: 2021-06-11
ISBN 10: 2889668738
ISBN 13: 9782889668731
Language: EN, FR, DE, ES & NL

Novel Cancer Treatments based on Autophagy Modulation Book Review:

Autophagy Cancer Other Pathologies Inflammation Immunity Infection and Aging

Autophagy  Cancer  Other Pathologies  Inflammation  Immunity  Infection  and Aging
Author: M. A. Hayat
Publsiher: Academic Press
Total Pages: 622
Release: 2017-09-07
ISBN 10: 0128121475
ISBN 13: 9780128121474
Language: EN, FR, DE, ES & NL

Autophagy Cancer Other Pathologies Inflammation Immunity Infection and Aging Book Review:

Autophagy: Cancer, Other Pathologies, Inflammation, Immunity, Infection, and Aging, Volume 12 discusses and details almost all aspects of the autophagy machinery in the context of health, cancer and other pathologies. Autophagy is more widely accepted as beneficial given its role in eliminating ‘toxic assets’ and promoting cell viability, hence, it has emerged as a new and potent modulator of disease progression that is both scientifically intriguing and clinically relevant. As the latest release in the Autophagy book series, users will find a detailed explanation of the role of molecular mechanisms. Presents the most advanced information regarding the role of the autophagic system in life and death States recent advancements in the molecular mechanisms underlying a large number of genetic and epigenetic diseases and abnormalities Summarizes the most up-to-date findings on how autophagy is executed and regulated at the molecular level and how its disruption can lead to disease Authored by global leaders in the field, bringing the broadest, most expert coverage available