Neuronal Networks in Brain Function CNS Disorders and Therapeutics

Neuronal Networks in Brain Function  CNS Disorders  and Therapeutics
Author: Carl Faingold,Hal Blumenfeld
Publsiher: Academic Press
Total Pages: 512
Release: 2013-12-26
ISBN 10: 0124158641
ISBN 13: 9780124158641
Language: EN, FR, DE, ES & NL

Neuronal Networks in Brain Function CNS Disorders and Therapeutics Book Review:

Neuronal Networks in Brain Function, CNS Disorders, and Therapeutics, edited by two leaders in the field, offers a current and complete review of what we know about neural networks. How the brain accomplishes many of its more complex tasks can only be understood via study of neuronal network control and network interactions. Large networks can undergo major functional changes, resulting in substantially different brain function and affecting everything from learning to the potential for epilepsy. With chapters authored by experts in each topic, this book advances the understanding of: How the brain carries out important tasks via networks How these networks interact in normal brain function Major mechanisms that control network function The interaction of the normal networks to produce more complex behaviors How brain disorders can result from abnormal interactions How therapy of disorders can be advanced through this network approach This book will benefit neuroscience researchers and graduate students with an interest in networks, as well as clinicians in neuroscience, pharmacology, and psychiatry dealing with neurobiological disorders. Utilizes perspectives and tools from various neuroscience subdisciplines (cellular, systems, physiologic), making the volume broadly relevant Chapters explore normal network function and control mechanisms, with an eye to improving therapies for brain disorders Reflects predominant disciplinary shift from an anatomical to a functional perspective of the brain Edited work with chapters authored by leaders in the field around the globe – the broadest, most expert coverage available

From Neurons to Neighborhoods

From Neurons to Neighborhoods
Author: Division of Behavioral and Social Sciences and Education,Institute of Medicine,Board on Children, Youth, and Families,Committee on Integrating the Science of Early Childhood Development
Publsiher: National Academies Press
Total Pages: 612
Release: 2000-11-13
ISBN 10: 0309069882
ISBN 13: 9780309069885
Language: EN, FR, DE, ES & NL

From Neurons to Neighborhoods Book Review:

How we raise young children is one of today's most highly personalized and sharply politicized issues, in part because each of us can claim some level of "expertise." The debate has intensified as discoveries about our development-in the womb and in the first months and years-have reached the popular media. How can we use our burgeoning knowledge to assure the well-being of all young children, for their own sake as well as for the sake of our nation? Drawing from new findings, this book presents important conclusions about nature-versus-nurture, the impact of being born into a working family, the effect of politics on programs for children, the costs and benefits of intervention, and other issues. The committee issues a series of challenges to decision makers regarding the quality of child care, issues of racial and ethnic diversity, the integration of children's cognitive and emotional development, and more. Authoritative yet accessible, From Neurons to Neighborhoods presents the evidence about "brain wiring" and how kids learn to speak, think, and regulate their behavior. It examines the effect of the climate-family, child care, community-within which the child grows.

Encyclopedia of Basic Epilepsy Research

Encyclopedia of Basic Epilepsy Research
Author: Anonim
Publsiher: Academic Press
Total Pages: 1832
Release: 2009-05-27
ISBN 10: 0123739616
ISBN 13: 9780123739612
Language: EN, FR, DE, ES & NL

Encyclopedia of Basic Epilepsy Research Book Review:

As a truly translational area of biomedical investigation, epilepsy research spans an extraordinary breadth of subjects and involves virtually every tool that modern neuroscience has at its disposal. The Encyclopedia of Basic Epilepsy Research provides an up to date, comprehensive reference for all epilepsy researchers. With an expert list of authors, the encyclopedia covers the full spectrum of research activities from genes and molecules to animal models and human patients. The encyclopedia's electronic format also provides unparalleled access to frequent updates and additions, while the limited edition print version provides another option for owning this content. The Encyclopedia of Basic Epilepsy Research is an essential resource for researchers of all levels and clinicians who study epilepsy. The only comprehensive reference for basic research and current activities in epilepsy Electronic format provides fast and easy access to updates and additions, with limited print version available as well Contains over 85 articles, all written by experts in epilepsy research

New Therapeutics for Traumatic Brain Injury

New Therapeutics for Traumatic Brain Injury
Author: Kim Heidenreich
Publsiher: Academic Press
Total Pages: 352
Release: 2016-09-27
ISBN 10: 0128027010
ISBN 13: 9780128027011
Language: EN, FR, DE, ES & NL

New Therapeutics for Traumatic Brain Injury Book Review:

New Therapeutics for Traumatic Brain Injury: Prevention of Secondary Brain Damage and Enhancement of Repair and Regeneration explores traumatic brain injury (TBI), a major cause of death and disability throughout the world. The delayed nature of the secondary injury phase suggests that there is a therapeutic window for pharmacological interventions or other approaches to prevent progressive tissue damage and improve functional outcomes. It is now apparent that therapeutic interventions should entail both protective and repair/regeneration strategies depending on the phase of brain injury. This book describes emerging experimental strategies for the treatment of TBI, including new anti-inflammatory or anti-apoptotic therapeutics that limit brain damage, and novel or repurposed drugs that enhance repair or regeneration of the brain after injury. Comprehensive overview of basic approaches and translational development of new therapies for TBI Edited by a prominent TBI researcher that includes contributions by leading global researchers in the field Presents a great resource for researchers and practitioners to learn more about the many evolving preclinical studies and clinical trials currently underway, and the challenges of bringing translational studies in TBI to the clinic

The Physics of the Mind and Brain Disorders

The Physics of the Mind and Brain Disorders
Author: Ioan Opris,Manuel F. Casanova
Publsiher: Springer
Total Pages: 793
Release: 2017-12-01
ISBN 10: 3319296744
ISBN 13: 9783319296746
Language: EN, FR, DE, ES & NL

The Physics of the Mind and Brain Disorders Book Review:

This book covers recent advances in the understanding of brain structure, function and disorders based on the fundamental principles of physics. It covers a broad range of physical phenomena occurring in the brain circuits for perception, cognition, emotion and action, representing the building blocks of the mind. It provides novel insights into the devastating brain disorders of the mind such as schizophrenia, dementia, autism, aging or addictions, as well as into the new devices for brain repair. The book is aimed at basic researchers in the fields of neuroscience, physics, biophysics and clinicians in the fields of neurology, neurosurgery, psychology, psychiatry.

Tinnitus Imaging Endovascular and Surgical Approaches An issue of Neuroimaging Clinics of North America E Book

Tinnitus  Imaging  Endovascular and Surgical Approaches  An issue of Neuroimaging Clinics of North America  E Book
Author: Prashant Raghavan,Dheeraj Gandhi
Publsiher: Elsevier Health Sciences
Total Pages: 145
Release: 2016-07-27
ISBN 10: 0323444741
ISBN 13: 9780323444743
Language: EN, FR, DE, ES & NL

Tinnitus Imaging Endovascular and Surgical Approaches An issue of Neuroimaging Clinics of North America E Book Book Review:

This issue of Neuroimaging Clinics of North America focuses on Imaging of Tinnitus. Articles will include: Neuroscience of Tinnitus; Clinical Evaluation of the Patient with Tinnitus; Arterial Abnormalities Leading to Tinnitus; Paragangliomas and Other Vascular Skull Base Tumors; Dural AV Fistulae: Imaging and Management; Venous Abnormalities Leading to Tinnitus: Imaging Evaluation; Endovascular Intervention in Venous Tinnitus: New Horizons and Future Directions; Emerging Role of Surgical Treatments in the Treatment of Tinnitus; Role of Advanced Neuroimaging and Future Directions; Imaging Interpretation of Temporal Bone Studies in a Patient with Tinnitus: A Systematic Approach; and much more!

Models of Seizures and Epilepsy

Models of Seizures and Epilepsy
Author: Asla Pitkänen,Paul Buckmaster, DVM, PhD,Aristea S Galanopoulou,Solomon L. Moshé
Publsiher: Academic Press
Total Pages: 1178
Release: 2017-06-14
ISBN 10: 012804067X
ISBN 13: 9780128040676
Language: EN, FR, DE, ES & NL

Models of Seizures and Epilepsy Book Review:

Models of Seizures and Epilepsy, Second Edition, is a valuable, practical reference for investigators who are searching for the most appropriate laboratory models to address key questions in the field. The book also provides an important background for physicians, fellows, and students, offering insight into the potential for advances in epilepsy research as well as R&D drug development. Contents include the current spectrum of models available to model different epilepsy syndromes, epilepsy in transgenic animals, comorbidities in models of epilepsy, and novel technologies to study seizures and epilepsies in animals. Provides a comprehensive reference detailing animal models of epilepsy and seizure Offers insights on the use of novel technologies that can be applied in experimental epilepsy research Edited by leading experts in the field that provide not only technical reviews of these models but also conceptual critiques Comments on the strengths and limitations of various models, including their relationship to clinical phenomenology and their value in developing better understanding and treatments

Almost Periodicity Chaos and Asymptotic Equivalence

Almost Periodicity  Chaos  and Asymptotic Equivalence
Author: Marat Akhmet
Publsiher: Springer
Total Pages: 360
Release: 2019-06-20
ISBN 10: 303020572X
ISBN 13: 9783030205720
Language: EN, FR, DE, ES & NL

Almost Periodicity Chaos and Asymptotic Equivalence Book Review:

The central subject of this book is Almost Periodic Oscillations, the most common oscillations in applications and the most intricate for mathematical analysis. Prof. Akhmet's lucid and rigorous examination proves these oscillations are a "regular" component of chaotic attractors. The book focuses on almost periodic functions, first of all, as Stable (asymptotically) solutions of differential equations of different types, presumably discontinuous; and, secondly, as non-isolated oscillations in chaotic sets. Finally, the author proves the existence of Almost Periodic Oscillations (asymptotic and bi-asymptotic) by asymptotic equivalence between systems. The book brings readers' attention to contemporary methods for considering oscillations as well as to methods with strong potential for study of chaos in the future. Providing three powerful instruments for mathematical research of oscillations where dynamics are observable and applied, the book is ideal for engineers as well as specialists in electronics, computer sciences, robotics, neural networks, artificial networks, and biology. Distinctively combines results and methods of the theory of differential equations with thorough investigation of chaotic dynamics with almost periodic ingredients; Provides all necessary mathematical basics in their most developed form, negating the need for any additional sources for readers to start work in the area; Presents a unique method of investigation of discontinuous almost periodic solutions in its unified form, employed to differential equations with different types of discontinuity; Develops the equivalence method to its ultimate effective state such that most important theoretical problems and practical applications can be analyzed by the method.

Update on Vascular Contributions to Age Related Neurodegenerative Diseases and Cognitive Impairment Research of ISNVD 2020 Meeting

Update on Vascular Contributions to Age Related Neurodegenerative Diseases and Cognitive Impairment   Research of ISNVD 2020 Meeting
Author: Yulin Ge,Mark Haacke,Meiyun Wang,Robert Zivadinov,Andreas Charidimou
Publsiher: Frontiers Media SA
Total Pages: 135
Release: 2021-12-02
ISBN 10: 288971764X
ISBN 13: 9782889717644
Language: EN, FR, DE, ES & NL

Update on Vascular Contributions to Age Related Neurodegenerative Diseases and Cognitive Impairment Research of ISNVD 2020 Meeting Book Review:

Neural Approaches to Dynamics of Signal Exchanges

Neural Approaches to Dynamics of Signal Exchanges
Author: Anna Esposito,Marcos Faundez-Zanuy,Francesco Carlo Morabito,Eros Pasero
Publsiher: Springer Nature
Total Pages: 525
Release: 2019-09-18
ISBN 10: 9811389500
ISBN 13: 9789811389504
Language: EN, FR, DE, ES & NL

Neural Approaches to Dynamics of Signal Exchanges Book Review:

The book presents research that contributes to the development of intelligent dialog systems to simplify diverse aspects of everyday life, such as medical diagnosis and entertainment. Covering major thematic areas: machine learning and artificial neural networks; algorithms and models; and social and biometric data for applications in human–computer interfaces, it discusses processing of audio-visual signals for the detection of user-perceived states, the latest scientific discoveries in processing verbal (lexicon, syntax, and pragmatics), auditory (voice, intonation, vocal expressions) and visual signals (gestures, body language, facial expressions), as well as algorithms for detecting communication disorders, remote health-status monitoring, sentiment and affect analysis, social behaviors and engagement. Further, it examines neural and machine learning algorithms for the implementation of advanced telecommunication systems, communication with people with special needs, emotion modulation by computer contents, advanced sensors for tracking changes in real-life and automatic systems, as well as the development of advanced human–computer interfaces. The book does not focus on solving a particular problem, but instead describes the results of research that has positive effects in different fields and applications.

Mechanisms of Neuroinflammation

Mechanisms of Neuroinflammation
Author: Gonzalo Emiliano Aranda Abreu
Publsiher: BoD – Books on Demand
Total Pages: 318
Release: 2017-08-23
ISBN 10: 9535134515
ISBN 13: 9789535134510
Language: EN, FR, DE, ES & NL

Mechanisms of Neuroinflammation Book Review:

"Mechanisms of Neuroinflammation" book explains how the neuronal cells become swollen at the moment of the blood-brain barrier disruption and how they lose their immunological isolation. A cascade of cytokines and immune cells from the bloodstream enters the nervous system, inflaming neurons and activating the glia. This produces a neuroinflammatory process that can generate different neurodegenerative diseases. Better understanding of mechanisms that are activated at the time when the damage to the brain occurs could lead to the development of suitable therapies that revert the neuronal inflammation and thus prevent further damage to the nervous system.

Neuromodulatory Control of Brainstem Function in Health and Disease

Neuromodulatory Control of Brainstem Function in Health and Disease
Author: Brian R. Noga,Mikhail Lebedev,Ioan Opris,Gordon S. Mitchell
Publsiher: Frontiers Media SA
Total Pages: 135
Release: 2020-03-25
ISBN 10: 2889635759
ISBN 13: 9782889635757
Language: EN, FR, DE, ES & NL

Neuromodulatory Control of Brainstem Function in Health and Disease Book Review:

Sigma Receptors Their Role in Disease and as Therapeutic Targets

Sigma Receptors  Their Role in Disease and as Therapeutic Targets
Author: Sylvia B. Smith,Tsung-Ping Su
Publsiher: Springer
Total Pages: 312
Release: 2017-03-16
ISBN 10: 3319501747
ISBN 13: 9783319501741
Language: EN, FR, DE, ES & NL

Sigma Receptors Their Role in Disease and as Therapeutic Targets Book Review:

Originally confused with opioid receptors and then orphan receptors with no biological function, Sigma Receptors are now recognized as relevant to many degenerative diseases with remarkable potential as therapeutic targets. In this text, new information about the structure of sigma 1 receptor, its binding sites are provided as well as its expression in many cell types. It’s putative role in degenerative neuronal diseases including amyotrophic lateral sclerosis, Alzheimer’s disease, Parkinson’s disease, Huntington’s disease, pain, drug addiction and locomotor activity. Their roles in possible treatments for blinding retinal diseases emphasize the tremendous far-reaching potential for ligands for these receptors. Exciting breakthroughs in this dynamic field in the last decade are reported herein, which will guide future investigators in determining the full potential of this unique, yet abundantly expressed protein.

Molecular and Cell Biology of Human Gene Therapeutics

Molecular and Cell Biology of Human Gene Therapeutics
Author: G. Dickson
Publsiher: Springer Science & Business Media
Total Pages: 403
Release: 2012-12-06
ISBN 10: 9401105472
ISBN 13: 9789401105477
Language: EN, FR, DE, ES & NL

Molecular and Cell Biology of Human Gene Therapeutics Book Review:

advanced metastatic disease of solid tumors, dictates that each tumor mass, indeed each individual metastasis, will have a unique antigen and cytokine environment and hence unique response to immune modu lation. A differential response to immunotherapy is thus inevitable. 4. Many of the human trials described are not randomized and report survival or response against historical controls. Most tumors described are immunogenic human tumors: renal cell cancer and melanoma are most common. In order to avoid the well-described inter-patient vari ation and rare incidence of spontaneous response among patient samples as well as selection bias and changes in practice over time, randomized trials are required. 5. Immunological treatment is unlike conventional chemotherapy in its endpoint. Most chemotherapeutic regimes require a complete response or a good partial response for cure or good palliation. There are now many cases where immunotherapy has provided long-term palliation without massive tumor reduction. Immunity may be stimulated to a degree which holds tumorigenicity in check and most importantly, pro vides good palliation for the patient in a manner that differs essentially from chemotherapy.

Pharmacology of GABA and Glycine Neurotransmission

Pharmacology of GABA and Glycine Neurotransmission
Author: Hanns Möhler
Publsiher: Springer Science & Business Media
Total Pages: 413
Release: 2012-12-06
ISBN 10: 3642568335
ISBN 13: 9783642568336
Language: EN, FR, DE, ES & NL

Pharmacology of GABA and Glycine Neurotransmission Book Review:

Highlighting the current developments and future directions in GABA and glycine research, this volume covers the major inhibitory neurotransmitters from the molecular mechanisms of signal transduction to their role in health and disease. It is of topical importance because these neurotransmitters are essential for brain function and therapy of diseases such as anxiety disorders, insomnias, epilepsy, depression, spasticity, and memory deficits. Distinguished scientists at the forefront of research contributed reviews on the role of these transmitters in governing neuronal networks, their signalling pathways, their receptors, the pharmacology of GABA A- and GABA B- and GABA C-receptors as well as of GABA- and glycine-transporters, and their role in disease. The volume serves as reference for pharmacologists/toxicologists, neuroscientists, neurologists and psychiatrists.

Fundamentals of Brain Network Analysis

Fundamentals of Brain Network Analysis
Author: Alex Fornito,Andrew Zalesky,Edward Bullmore
Publsiher: Academic Press
Total Pages: 494
Release: 2016-03-04
ISBN 10: 0124081185
ISBN 13: 9780124081185
Language: EN, FR, DE, ES & NL

Fundamentals of Brain Network Analysis Book Review:

Fundamentals of Brain Network Analysis is a comprehensive and accessible introduction to methods for unraveling the extraordinary complexity of neuronal connectivity. From the perspective of graph theory and network science, this book introduces, motivates and explains techniques for modeling brain networks as graphs of nodes connected by edges, and covers a diverse array of measures for quantifying their topological and spatial organization. It builds intuition for key concepts and methods by illustrating how they can be practically applied in diverse areas of neuroscience, ranging from the analysis of synaptic networks in the nematode worm to the characterization of large-scale human brain networks constructed with magnetic resonance imaging. This text is ideally suited to neuroscientists wanting to develop expertise in the rapidly developing field of neural connectomics, and to physical and computational scientists wanting to understand how these quantitative methods can be used to understand brain organization. Extensively illustrated throughout by graphical representations of key mathematical concepts and their practical applications to analyses of nervous systems Comprehensively covers graph theoretical analyses of structural and functional brain networks, from microscopic to macroscopic scales, using examples based on a wide variety of experimental methods in neuroscience Designed to inform and empower scientists at all levels of experience, and from any specialist background, wanting to use modern methods of network science to understand the organization of the brain

The Brain That Changes Itself

The Brain That Changes Itself
Author: Norman Doidge
Publsiher: Penguin
Total Pages: 448
Release: 2007-03-15
ISBN 10: 1101147113
ISBN 13: 9781101147115
Language: EN, FR, DE, ES & NL

The Brain That Changes Itself Book Review:

“Fascinating. Doidge’s book is a remarkable and hopeful portrait of the endless adaptability of the human brain.”—Oliver Sacks, MD, author of The Man Who Mistook His Wife for a Hat What is neuroplasticity? Is it possible to change your brain? Norman Doidge’s inspiring guide to the new brain science explains all of this and more An astonishing new science called neuroplasticity is overthrowing the centuries-old notion that the human brain is immutable, and proving that it is, in fact, possible to change your brain. Psychoanalyst, Norman Doidge, M.D., traveled the country to meet both the brilliant scientists championing neuroplasticity, its healing powers, and the people whose lives they’ve transformed—people whose mental limitations, brain damage or brain trauma were seen as unalterable. We see a woman born with half a brain that rewired itself to work as a whole, blind people who learn to see, learning disorders cured, IQs raised, aging brains rejuvenated, stroke patients learning to speak, children with cerebral palsy learning to move with more grace, depression and anxiety disorders successfully treated, and lifelong character traits changed. Using these marvelous stories to probe mysteries of the body, emotion, love, sex, culture, and education, Dr. Doidge has written an immensely moving, inspiring book that will permanently alter the way we look at our brains, human nature, and human potential.

Brain Extracellular Matrix in Health and Disease

Brain Extracellular Matrix in Health and Disease
Author: Anonim
Publsiher: Elsevier
Total Pages: 506
Release: 2014-10-30
ISBN 10: 0444634940
ISBN 13: 9780444634948
Language: EN, FR, DE, ES & NL

Brain Extracellular Matrix in Health and Disease Book Review:

In the central nervous system, extracellular matrix (ECM) molecules, including hyaluronic acid, chondroitin and heparan sulfate proteoglycans, tenascins, reelin and agrin, along with their remodelling enzymes, such as neurotrypsin, neuropsin, plasminogen activators, and metalloproteinases, are secreted by neural and non-neural cells into the extracellular space to form the ECM and signal via ECM receptors. Despite recent advances in the ECM field, the importance of neural ECM for physiological and pathological processes is currently less widely recognized than that of other CNS elements. This book will enlighten recent progress in our understanding of mechanisms by which neural ECM, its receptors and activity-dependent ECM remodeling regulate neural development, synaptic plasticity, and contribute to pathological changes in the brain. In the first part, the roles of ECM signaling and proteolytic modification of ECM in neurogenesis, neural migration, axonal pathfinding, synaptogenesis, synaptic and homeostatic plasticity will be discussed. The second part will focus on the emerging ECM-dependent mechanisms associated with CNS injury, epilepsy, neurodegenerative and neuropsychiatric diseases. For further development of neural ECM field, a very important contribution is the third part of the book, which is devoted to neural ECM-targeting tools and therapeutics. The concluding fourth part will highlight advances in development of artificial ECM and ECM-based systems suitable for multisite recording and stimulation of neural cells. Authors are the leading experts in the field of brain extracellular matrix in health and disease Book covers the most important aspects of brain extracellular matrix in health and disease Interesting for both scientists and clinicians

Translational Research in Traumatic Brain Injury

Translational Research in Traumatic Brain Injury
Author: Daniel Laskowitz,Gerald Grant
Publsiher: CRC Press
Total Pages: 412
Release: 2015-12-01
ISBN 10: 1498766579
ISBN 13: 9781498766579
Language: EN, FR, DE, ES & NL

Translational Research in Traumatic Brain Injury Book Review:

Traumatic brain injury (TBI) remains a significant source of death and permanent disability, contributing to nearly one-third of all injury related deaths in the United States and exacting a profound personal and economic toll. Despite the increased resources that have recently been brought to bear to improve our understanding of TBI, the development of new diagnostic and therapeutic approaches has been disappointingly slow. Translational Research in Traumatic Brain Injury attempts to integrate expertise from across specialties to address knowledge gaps in the field of TBI. Its chapters cover a wide scope of TBI research in five broad areas: Epidemiology Pathophysiology Diagnosis Current treatment strategies and sequelae Future therapies Specific topics discussed include the societal impact of TBI in both the civilian and military populations, neurobiology and molecular mechanisms of axonal and neuronal injury, biomarkers of traumatic brain injury and their relationship to pathology, neuroplasticity after TBI, neuroprotective and neurorestorative therapy, advanced neuroimaging of mild TBI, neurocognitive and psychiatric symptoms following mild TBI, sports-related TBI, epilepsy and PTSD following TBI, and more. The book integrates the perspectives of experts across disciplines to assist in the translation of new ideas to clinical practice and ultimately to improve the care of the brain injured patient.

Functional Neurologic Disorders

Functional Neurologic Disorders
Author: Anonim
Publsiher: Academic Press
Total Pages: 680
Release: 2016-10-06
ISBN 10: 0128018496
ISBN 13: 9780128018491
Language: EN, FR, DE, ES & NL

Functional Neurologic Disorders Book Review:

Functional Neurologic Disorders, the latest volume in the Handbook of Clinical Neurology series, summarizes state-of-the-art research findings and clinical practice on this class of disorders at the interface between neurology and psychiatry. This 51-chapter volume offers an historical introduction, chapters on epidemiology and pathophysiolology, a large section on the clinical features of different type of functional neurologic symptoms and disorders (including functional movement disorders, non-epileptic seizures, dizziness, vision, hearing, speech and cognitive symptoms), and then concluding with approaches to therapy. This group of internationally acclaimed experts in neurology, psychiatry, and neuroscience represent a broad spectrum of areas of expertise, chosen for their ability to write clearly and concisely with an eye toward a clinical audience. This HCN volume sets a new landmark standard for a comprehensive, multi-authored work dealing with functional neurologic disorders (also described as psychogenic, dissociative or conversion disorders). Offers a comprehensive interdisciplinary approach for the care of patients with functional disorders seen in neurologic practice, leading to more efficient prevention, management, and treatment Provides a synthesis of research efforts incorporating clinical, brain imaging and neurophysiological studies Fills an existing gap between traditional neurology and traditional psychiatry Contents include coverage of history, epidemiology, clinical presentations, and therapy Edited work with chapters authored by leaders in the field, the broadest, most expert coverage available