Molecular Imaging

Molecular Imaging
Author: Brian D. Ross,Sanjiv S. Gambhir
Publsiher: Academic Press
Total Pages: 1500
Release: 2021-08-15
ISBN 10: 9780128163863
ISBN 13: 0128163860
Language: EN, FR, DE, ES & NL

Molecular Imaging Book Review:

The detection and measurement of the dynamic interactions of proteins within the living cell are critical to the understanding of cell physiology and pathophysiology. The field of molecular imaging of living subjects continues to expand and has seen dramatic advances in chemistry, engineering and biomedical applications. Molecular Imaging: Principles and Practice, Second Edition provides the first point of entry to the research for all scientists interested in this multi-disciplinary field. Molecular imaging is very diverse: new investigators, collaborators, and students entering this field need an authoritative reference to bring this field together. Editors Brian Ross and Sam Gambhir designed this revision precisely to fill this need. The most authoritative and effective resource available in the field, written by over 170 of the leading scientists from around the world who have evaluated and summarized the most important methods, principles, technologies and data within the field Concepts illustrated with over 600 color figures and molecular-imaging examples This edition packed with innovative science, including: Light sheet fluorescence microscopy (LSFM); Mass Spectrometry Imaging; Combining In vitro and in vivo diagnostics; Raman Imaging; Optogenetics; FDA approval of current imaging agents

Targeted Molecular Imaging

Targeted Molecular Imaging
Author: Michael J. Welch,William C. Eckelman
Publsiher: CRC Press
Total Pages: 388
Release: 2012-02-24
ISBN 10: 1439841950
ISBN 13: 9781439841952
Language: EN, FR, DE, ES & NL

Targeted Molecular Imaging Book Review:

Targeted Molecular Imaging covers the development of novel diagnostic approaches that use an imaging probe and agent to noninvasively visualize cellular processes in normal and disease states. It discusses the concept, development, preclinical studies, and, in many cases, translation to the clinic of targeted imaging agents. The many case studies that form the core of this book deal with the development and translation of non-nuclear probes and radiotracers; other sections address critical topics such as In vitro studies, small animal research, and the application of targeted probes for nuclear, optical and MRI imaging. The chapters use a common format to demonstrate how various investigators approach the comprehensive task of validating a new targeted probe. Targeted Molecular Imaging is a timely resource for a rapidly advancing field, and addresses: Various methods of validating a new targeted probe through examples from human studies with imaging of breast cancer, cardiovascular disease, and neurodegenerative diseases Basic principles, disease models, imaging studies in animals, imaging in initial human studies, and the application of molecular imaging in pharmacy and drug discovery In vitro studies, small animal studies, and targeted radiopharmaceuticals Using these case studies, investigators can generalize and apply the information to their own specific targeted probe. The insights provided by the contributors, experts who have developed these approaches in their own groups, help guide scientists planning to translate imaging agents from the concept stage to clinical application.

Essentials of Nuclear Medicine and Molecular Imaging E Book

Essentials of Nuclear Medicine and Molecular Imaging E Book
Author: Fred A. Mettler,Milton J. Guiberteau
Publsiher: Elsevier Health Sciences
Total Pages: 624
Release: 2018-08-17
ISBN 10: 0323567894
ISBN 13: 9780323567893
Language: EN, FR, DE, ES & NL

Essentials of Nuclear Medicine and Molecular Imaging E Book Book Review:

Covering both the fundamentals and recent developments in this fast-changing field, Essentials of Nuclear Medicine and Molecular Imaging, 7th Edition, is a must-have resource for radiology residents, nuclear medicine residents and fellows, nuclear medicine specialists, and nuclear medicine technicians. Known for its clear and easily understood writing style, superb illustrations, and self-assessment features, this updated classic is an ideal reference for all diagnostic imaging and therapeutic patient care related to nuclear medicine, as well as an excellent review tool for certification or MOC preparation. Provides comprehensive, clear explanations of everything from principles of human physiology, pathology, physics, radioactivity, radiopharmaceuticals, radiation safety, and legal requirements to hot topics such as new brain and neuroendocrine tumor agents and hybrid imaging, including PET/MR and PET/CT. Covers the imaging of every body system, as well as inflammation, infection and tumor imaging; pearls and pitfalls for every chapter; and pediatric doses and guidelines in compliance with the Image Gently and Image Wisely programs. Features a separate self-assessment section on differential diagnoses, imaging procedures and artifacts, and safety issues with unknown cases, questions, answers, and explanations. Includes new images and illustrations, for a total of 430 high-quality, multi-modality examples throughout the text. Reflects recent advances in the field, including updated nuclear medicine imaging and therapy guidelines • Updated dosimetry values and effective doses for all radiopharmaceuticals with new values from the 2015 International Commission on Radiological Protection • Updated information regarding advances in brain imaging, including amyloid, dopamine transporter and dementia imaging • Inclusion of Ga-68 DOTA PET/CT for neuroendocrine tumors • Expanded information on correlative and hybrid imaging with SPECT/CT • New myocardial agents • and more. Contains extensive appendices including updated comprehensive imaging protocols for routine and hybrid imaging, pregnancy and breastfeeding guidelines, pediatric dosages, non-radioactive pharmaceuticals used in interventional and cardiac stress imaging, and radioactivity conversion tables.

Molecular Imaging in Oncology

Molecular Imaging in Oncology
Author: Martin G. Pomper,Juri G. Gelovani
Publsiher: CRC Press
Total Pages: 744
Release: 2008-10-13
ISBN 10: 1000654400
ISBN 13: 9781000654400
Language: EN, FR, DE, ES & NL

Molecular Imaging in Oncology Book Review:

With molecular imaging becoming one the fastest growing topics in medical schools, Informa Healthcare presents Molecular Imaging in Oncology, the first comprehensive reference on molecular imaging in oncology.Giving clinicians and researchers a greater understanding of the current field, this text covers:instrumentation and techniquescancer imaging

Molecular Imaging

Molecular Imaging
Author: Ammasi Periasamy,Richard Day
Publsiher: Elsevier
Total Pages: 312
Release: 2011-04-28
ISBN 10: 9780080536873
ISBN 13: 0080536875
Language: EN, FR, DE, ES & NL

Molecular Imaging Book Review:

The detection and measurement of the dynamic interactions of proteins within the living cell are critical to our understanding of cell physiology and pathophysiology. With FRET microscopy and spectroscopy techniques, basic and clinical scientists can make such measurements at very high spatial and temporal resolution. But sources of background information about these tools are very limited, so this book fills an important gap. It covers both the basic concepts and theory behind the various FRET microscopy and spectroscopy techniques, and the practical aspects of using the techniques and analyzing the results. The critical tricks for obtaining a good FRET image and precisely quantitating the signals from living specimens at the nanomolecular level are explained. Valuable information about the preparation of biological samples used for FRET image analysis is also provided. The methods covered include different types of microscopy systems and detectors (wide-field, confocal, multi-photon) as well as specialized techniques such as photobleaching FRET, FLIM-FRET microscopy, spectral imaging FRET, single molecule FRET, and time and image correlation spectroscopy. Starting from the basics, the chapters guide readers through the choice of probes to be used for FRET experiments and the selection of the most suitable experimental approaches to address specific biological questions. Up-to-date, consistently organized, and well-illustrated, this unique book will be welcomed by all researchers who wish to use FRET microscopy and spectroscopy techniques.

The Chemistry of Molecular Imaging

The Chemistry of Molecular Imaging
Author: Nicholas Long,Wing-Tak Wong,Edmund H. Immergut
Publsiher: John Wiley & Sons
Total Pages: 408
Release: 2014-12-22
ISBN 10: 1118093275
ISBN 13: 9781118093276
Language: EN, FR, DE, ES & NL

The Chemistry of Molecular Imaging Book Review:

Covering all the fundamentals of modern imaging methodologies, including their techniques and application within medicine and industry, The Chemistry of Molecular Engineering focuses primarily on the chemistry of probes and imaging agents, as well as chemical methodology for labelling and bioconjugation. Written by an interdisciplinary team of experts, this book investigates the chemistry of molecular imaging and helps to educate non-chemists already involved in the area of molecular imaging. It addresses all the major modalities and techniques, such as MRI, positron emission tomography, single photon emission computed tomography, ultrasound, and fluorescence/optical imaging.

Molecular Imaging

Molecular Imaging
Author: Ralph Weissleder
Publsiher: PMPH-USA
Total Pages: 1357
Release: 2010
ISBN 10: 9781607950059
ISBN 13: 1607950057
Language: EN, FR, DE, ES & NL

Molecular Imaging Book Review:

The field of molecular imaging of living subjects have evolved considerably and have seen spectacular advances in chemistry, engineering and biomedical applications. This textbook was designed to fill the need for an authoritative source for this multi-disciplinary field. We have been fortunate to recruit over 80 leading authors contributing 75 individual chapters. Given the multidisciplinary nature of the field, the book is broken into six different sections: "Molecular Imaging technologies", "Chemistry", "Molecular Imaging in Cell and Molecular Biology", "Applications of Molecular Imaging", "Molecular Imaging in Drug Evaluation" with the final section comprised of chapters on computation, bioinformatics and modeling. The organization of this large amount of information is logical and strives to avoid redundancies among chapters. It encourages the use of figures to illustrate concepts and to provide numerous molecular imaging examples.

Molecular Imaging

Molecular Imaging
Author: Shankar Vallabhajosula
Publsiher: Springer Science & Business Media
Total Pages: 372
Release: 2009-07-13
ISBN 10: 3540767355
ISBN 13: 9783540767350
Language: EN, FR, DE, ES & NL

Molecular Imaging Book Review:

Radioisotope-based molecular imaging probes provide unprecedented insight into biochemistry and function involved in both normal and disease states of living systems, with unbiased in vivo measurement of regional radiotracer activities offering very high specificity and sensitivity. No other molecular imaging technology including functional magnetic resonance imaging (fMRI) can provide such high sensitivity and specificity at a tracer level. The applications of this technology can be very broad ranging from drug development, pharmacokinetics, clinical investigations, and finally to routine diagnostics in radiology. The design and the development of radiopharmaceuticals for molecular imaging studies using PET/MicroPET or SPECT/MicroSPECT are a unique challenge. This book is intended for a broad audience and written with the main purpose of educating the reader on various aspects including potential clinical utility, limitations of drug development, and regulatory compliance and approvals.

Molecular Imaging Basic Principles And Applications In Biomedical Research 3rd Edition

Molecular Imaging  Basic Principles And Applications In Biomedical Research  3rd Edition
Author: Markus Rudin
Publsiher: World Scientific
Total Pages: 800
Release: 2020-04-04
ISBN 10: 1786346869
ISBN 13: 9781786346865
Language: EN, FR, DE, ES & NL

Molecular Imaging Basic Principles And Applications In Biomedical Research 3rd Edition Book Review:

The area of molecular imaging has matured over the past decade and is still growing rapidly. Many concepts developed for molecular biology and cellular imaging have been successfully translated to in vivo imaging of intact organisms. Molecular imaging enables the study of processes at a molecular level in their full biological context. Due to the high specificity of the molecular readouts the approach bears a high potential for diagnostics. It is fair to say that molecular imaging has become an indispensable tool for biomedical research and drug discovery and development today.This volume familiarizes the reader with the concepts of imaging and molecular imaging in particular. Basic principles of imaging technologies, reporter moieties for the various imaging modalities, and the design of targeted probes are described in the first part. The second part illustrates how these tools can be used to visualize relevant molecular events in the living organism. Topics covered include the studies of the biodistribution of reporter probes and drugs, visualization of the expression of biomolecules such as receptors and enzymes, and how imaging can be used for analyzing consequences of the interaction of a ligand or a drug with its molecular target by visualizing signal transduction, or assessing the metabolic, physiological, or structural response of the organism studied.The third edition has been extended considerably. This holds for the chapter on imaging modalities, which now includes sections on intravital microscopy and mass spectrometric imaging. All chapters have been updated and a new chapter on the challenges of translating molecular imaging solutions for clinical use has been added.

Molecular Imaging

Molecular Imaging
Author: Hossein Jadvar,Michael Graham,Heather Jacene
Publsiher: Cambridge University Press
Total Pages: 94
Release: 2017-10-31
ISBN 10: 1107621283
ISBN 13: 9781107621282
Language: EN, FR, DE, ES & NL

Molecular Imaging Book Review:

Trace the history, and advances in the field of molecular imaging, with this guide to the visual world of disease.

Nuclear Medicine and Molecular Imaging The Requisites E Book

Nuclear Medicine and Molecular Imaging  The Requisites E Book
Author: Janis P. O'Malley,Harvey A. Ziessman
Publsiher: Elsevier Health Sciences
Total Pages: 464
Release: 2020-05-20
ISBN 10: 0323550746
ISBN 13: 9780323550741
Language: EN, FR, DE, ES & NL

Nuclear Medicine and Molecular Imaging The Requisites E Book Book Review:

Now in its 5th Edition, this outstanding volume in the popular Requisites series thoroughly covers the fast-changing field of nuclear medicine and molecular imaging. Ideal for residency, clinical rotations, and board review, this compact and authoritative volume by Drs. Janis O'Malley and Harvey Ziessman covers the conceptual, factual, and interpretive information you need to know for success on exams and in clinical practice. NEW to this edition: More content on molecular imaging and the latest advances in clinical applications, including positron emission tomography (PET), SPECT/CT, PET/CT, and PET/MRI hybrid imaging. Inclusion of newly approved tracers such as Ga68 DOTA, F-18 amyloid, and F-18 PSMA. Expanded and integrated content on physics and non-interpretive aspects, including regulatory issues, radiation safety, and quality control. Up-to-date applications of nuclear medicine in the endocrine, skeletal, hepatobiliary, genitourinary, pulmonary, gastrointestinal, central nervous, and cardiac systems, as well as PET applications for oncology. In the outstanding Requisites tradition, the 5th Edition also: Summarizes key information with numerous outlines, tables, pearls, pitfalls, and frequently asked questions. Focuses on essentials to pass the certifying board exam and ensure accurate diagnoses in clinical practice. Helps you clearly visualize the findings you're likely to see in practice and on exams with nearly 200 full-color images.

Pediatric Nuclear Medicine

Pediatric Nuclear Medicine
Author: S.T. Treves
Publsiher: Springer Science & Business Media
Total Pages: 338
Release: 2013-11-11
ISBN 10: 1475718748
ISBN 13: 9781475718744
Language: EN, FR, DE, ES & NL

Pediatric Nuclear Medicine Book Review:

The 3rd edition of this classic – considered the standard in the field - reflects the latest advances in PET, SPECT, and oncology. Updated to incorporate cutting-edge diagnostic techniques, it serves as a bedrock resource for physicians whose nuclear medicine practices include children and provides a vast amount of background material for residents in training. The new edition retains the fundamental standard of excellence that earned its predecessors such a distinguished reputation. It has been thoroughly updated to incorporate cutting-edge diagnostic techniques. Pediatric Nuclear Medicine/PET, Third Edition is an indispensable resource for physicians whose practices include children and provides a vast amount of background material for residents in training.

Handbook of Nuclear Medicine and Molecular Imaging for Physicists

Handbook of Nuclear Medicine and Molecular Imaging for Physicists
Author: Michael Ljungberg
Publsiher: CRC Press
Total Pages: 316
Release: 2022-01-25
ISBN 10: 042995221X
ISBN 13: 9780429952210
Language: EN, FR, DE, ES & NL

Handbook of Nuclear Medicine and Molecular Imaging for Physicists Book Review:

Mathematical modelling is an important part of nuclear medicine. Therefore, several chapters of this book have been dedicated towards describing this topic. In these chapters, an emphasis has been put on describing the mathematical modelling of the radiation transport of photons and electrons, as well as on the transportation of radiopharmaceuticals between different organs and compartments. It also includes computer models of patient dosimetry. Two chapters of this book are devoted towards introducing the concept of biostatistics and radiobiology. These chapters are followed by chapters detailing dosimetry procedures commonly used in the context of diagnostic imaging, as well as patient-specific dosimetry for radiotherapy treatments. For safety reasons, many of the methods used in nuclear medicine and molecular imaging are tightly regulated. Therefore, this volume also highlights the basic principles for radiation protection. It discusses the process of how guidelines and regulations aimed at minimizing radiation exposure are determined and implemented by international organisations. Finally, this book describes how different dosimetry methods may be utilized depending on the intended target, including whole-body or organ-specific imaging, as well as small-scale to cellular dosimetry. This text will be an invaluable resource for libraries, institutions, and clinical and academic medical physicists searching for a complete account of what defines nuclear medicine. The most comprehensive reference available providing a state-of-the-art overview of the field of nuclear medicine Edited by a leader in the field, with contributions from a team of experienced medical physicists, chemists, engineers, scientists, and clinical medical personnel Includes the latest practical research in the field, in addition to explaining fundamental theory and the field's history

Aptamers

Aptamers
Author: Rakesh N. Veedu
Publsiher: CRC Press
Total Pages: 386
Release: 2017-03-03
ISBN 10: 9814669849
ISBN 13: 9789814669849
Language: EN, FR, DE, ES & NL

Aptamers Book Review:

Aptamers, often termed as ‘chemical antibodies,’ are an emerging class of synthetic ligands for efficient target-specific molecular recognition. The objective of this book is to highlight recent advances and potential of aptamers in various disease conditions. . This book focuses on the applications of aptamers in targeted nanotherapy, detection, and in molecular imaging in various disease conditions such as cancer, neurological diseases and infectious diseases.

Handbook of Nuclear Medicine and Molecular Imaging

Handbook of Nuclear Medicine and Molecular Imaging
Author: E. Edmund Kim,Dong-Soo Lee,Richard P. Baum
Publsiher: World Scientific
Total Pages: 448
Release: 2012
ISBN 10: 9814366234
ISBN 13: 9789814366236
Language: EN, FR, DE, ES & NL

Handbook of Nuclear Medicine and Molecular Imaging Book Review:

This handbook will provide updated information on nuclear medicine and molecular imaging techniques as well as its clinical applications, including radionuclide therapy, to trainees and practitioners of nuclear medicine, radiology and general medicine. Updated information on nuclear medicine and molecular imaging are vitally important and useful to both trainees and existing practitioners. Imaging techniques and agents are advancing and changing so rapidly that concise and pertinent information are absolutely necessary and helpful. It is hoped that this handbook will help readers be better equipped for the utilization of new imaging methods and treatments using radiopharmaceuticals.

Handbook of Nuclear Medicine and Molecular Imaging for Physicists

Handbook of Nuclear Medicine and Molecular Imaging for Physicists
Author: Michael Ljungberg
Publsiher: CRC Press
Total Pages: 654
Release: 2022-01-24
ISBN 10: 0429952252
ISBN 13: 9780429952258
Language: EN, FR, DE, ES & NL

Handbook of Nuclear Medicine and Molecular Imaging for Physicists Book Review:

This state-of-the-art handbook, the first in a series that provides medical physicists with a comprehensive overview into the field of nuclear medicine, is dedicated to instrumentation and imaging procedures in nuclear medicine. It provides a thorough treatment on the cutting-edge technologies being used within the field, in addition to touching upon the history of their use, their development, and looking ahead to future prospects. This text will be an invaluable resource for libraries, institutions, and clinical and academic medical physicists searching for a complete account of what defines nuclear medicine. The most comprehensive reference available providing a state-of-the-art overview of the field of nuclear medicine Edited by a leader in the field, with contributions from a team of experienced medical physicists Includes the latest practical research in the field, in addition to explaining fundamental theory and the field's history

In Vivo Molecular Imaging Probes for Alzheimer s Disease

In Vivo Molecular Imaging Probes for Alzheimer s Disease
Author: Eric Dustin Agdeppa
Publsiher: Ann Arbor, Mich. : University Microfilms International
Total Pages: 330
Release: 2002
ISBN 10: 1928374650XXX
ISBN 13: UCLA:L0084443399
Language: EN, FR, DE, ES & NL

In Vivo Molecular Imaging Probes for Alzheimer s Disease Book Review:

Molecular Imaging in Oncology

Molecular Imaging in Oncology
Author: Otmar Schober,Burkhard Riemann
Publsiher: Springer Science & Business Media
Total Pages: 416
Release: 2012-11-28
ISBN 10: 3642108539
ISBN 13: 9783642108532
Language: EN, FR, DE, ES & NL

Molecular Imaging in Oncology Book Review:

The impact of molecular imaging on diagnostics, therapy, and follow-up in oncology is increasing steadily. Many innovative molecular imaging probes have already entered clinical practice, and there is no doubt that the future emphasis will be on multimodality imaging in which morphological, functional, and molecular imaging techniques are combined in a single clinical investigation. This handbook addresses all aspects of molecular imaging in oncology, from basic research to clinical applications. The first section is devoted to technology and probe design, and examines a variety of PET and SPECT tracers as well as multimodality probes. Preclinical studies are then discussed in detail, with particular attention to multimodality imaging. In the third section, diverse clinical applications are presented, and the book closes by looking at future challenges. This handbook will be of value to all who are interested in the revolution in diagnostic oncology that is being brought about by molecular imaging.

PET

PET
Author: Michael E. Phelps
Publsiher: Springer Science & Business Media
Total Pages: 622
Release: 2012-12-06
ISBN 10: 0387225293
ISBN 13: 9780387225296
Language: EN, FR, DE, ES & NL

PET Book Review:

This book is written as both a text and a reference book. It contains numerous images from the biological sciences and clinical practice, tables, graphs, and fig ures, as well as exercises that are worked out to aid the reader in understanding principles or solving problems. In some cases, derivations are placed in appen dices so as not to break up the flow of the subject matter in the text. The book is intended for a broad audience interested in molecular imaging with positron emission tomography (PET). It is expected that the readers will range from undergraduate, graduate, and medical students to residents, physi cians, and scientists with backgrounds from various physical, biological, and medical specialty areas. Each chapter presents material in a straightforward man ner that is well illustrated and explained. Because of the diverse audience for the book, certain chapters or sections of chapters will be of more interest than oth ers to certain segments of the readership. Chapter 1 introduces the fundamental physics upon which PET imaging sys tems is based and discusses in detail the technologies and methods used to pro duce PET images. The chapter starts out by reviewing the physics of positron emission and annihilation and explains how positron range and photon non colinearity in coincidence detection place certain limits on spatial resolution.

Molecular Imaging

Molecular Imaging
Author: Bernhard Schaller
Publsiher: BoD – Books on Demand
Total Pages: 402
Release: 2012-03-16
ISBN 10: 9535103598
ISBN 13: 9789535103592
Language: EN, FR, DE, ES & NL

Molecular Imaging Book Review:

The present book gives an exceptional overview of molecular imaging. Practical approach represents the red thread through the whole book, covering at the same time detailed background information that goes very deep into molecular as well as cellular level. Ideas how molecular imaging will develop in the near future present a special delicacy. This should be of special interest as the contributors are members of leading research groups from all over the world.