Applications of Modern Linguistics

Applications of Modern Linguistics
Author: Moha Ennaji,Fatima Sadiqi
Publsiher: Unknown
Total Pages: 348
Release: 1994
ISBN 10: 1928374650XXX
ISBN 13: UOM:39015034200652
Language: EN, FR, DE, ES & NL

Applications of Modern Linguistics Book Review:

Innovative Strategies Statistical Solutions and Simulations for Modern Clinical Trials

Innovative Strategies  Statistical Solutions and Simulations for Modern Clinical Trials
Author: Mark Chang,John Balser,Jim Roach,Robin Bliss
Publsiher: CRC Press
Total Pages: 362
Release: 2019-03-29
ISBN 10: 1351214527
ISBN 13: 9781351214520
Language: EN, FR, DE, ES & NL

Innovative Strategies Statistical Solutions and Simulations for Modern Clinical Trials Book Review:

"This is truly an outstanding book. [It] brings together all of the latest research in clinical trials methodology and how it can be applied to drug development.... Chang et al provide applications to industry-supported trials. This will allow statisticians in the industry community to take these methods seriously." Jay Herson, Johns Hopkins University The pharmaceutical industry's approach to drug discovery and development has rapidly transformed in the last decade from the more traditional Research and Development (R & D) approach to a more innovative approach in which strategies are employed to compress and optimize the clinical development plan and associated timelines. However, these strategies are generally being considered on an individual trial basis and not as part of a fully integrated overall development program. Such optimization at the trial level is somewhat near-sighted and does not ensure cost, time, or development efficiency of the overall program. This book seeks to address this imbalance by establishing a statistical framework for overall/global clinical development optimization and providing tactics and techniques to support such optimization, including clinical trial simulations. Provides a statistical framework for achieve global optimization in each phase of the drug development process. Describes specific techniques to support optimization including adaptive designs, precision medicine, survival-endpoints, dose finding and multiple testing. Gives practical approaches to handling missing data in clinical trials using SAS. Looks at key controversial issues from both a clinical and statistical perspective. Presents a generous number of case studies from multiple therapeutic areas that help motivate and illustrate the statistical methods introduced in the book. Puts great emphasis on software implementation of the statistical methods with multiple examples of software code (both SAS and R). It is important for statisticians to possess a deep knowledge of the drug development process beyond statistical considerations. For these reasons, this book incorporates both statistical and "clinical/medical" perspectives.

Foundations of Evidence Based Medicine

Foundations of Evidence Based Medicine
Author: Milos Jenicek
Publsiher: CRC Press
Total Pages: 400
Release: 2019-09-19
ISBN 10: 0429584350
ISBN 13: 9780429584350
Language: EN, FR, DE, ES & NL

Foundations of Evidence Based Medicine Book Review:

This comprehensive text focuses on reasoning, critical thinking and pragmatic decision making in medicine. Based on the author’s extensive experience and filled with definitions, formulae, flowcharts and checklists, this fully revised second edition continues to provide invaluable guidance to the crucial role that clinical epidemiology plays in the expanding field of evidence-based medicine. Key Features: • Considers evidence-based medicine as a universal initiative common to all health sciences and professions, and all specialties within those disciplines • Demonstrates how effective practice is reliant on proper foundations, such as clinical and fundamental epidemiology, and biostatistics • Introduces the reader to basic epidemiological methods, meta-analysis and decision analysis • Shows that structured, modern, argumentative reasoning is required to build the best possible evidence and use it in practice and research • Outlines how to make the most appropriate decisions in clinical care, disease prevention and health promotion Presenting a range of topics seldom seen in a single resource, the innovative blend of informal logic and structured evidence-based reasoning makes this book invaluable for anyone seeking broad, in-depth and readable coverage of this complex and sometimes controversial field.

Contemporary Psychiatry

Contemporary Psychiatry
Author: Fritz Henn,Norman Sartorius,Hanfried Helmchen,Hans Lauter
Publsiher: Springer Science & Business Media
Total Pages: 2260
Release: 2013-11-11
ISBN 10: 3642595197
ISBN 13: 9783642595196
Language: EN, FR, DE, ES & NL

Contemporary Psychiatry Book Review:

The German version of this work has a long tradition, and this fourth edition is the first to see an English version. Its main feature is the international approach regarding both authors and topics. The four internationally renowned editors were able to acquire the leading specialists for each field as contributors to the book. No less than 120 authors, half of them from non-German speaking countries, ensure an extremely high standard and that cross-cultural aspects are considered. Another major feature is that the book presents the evidence such that it may be examined from at least four different entry points -- via basic disciplines of psychiatric knowledge about groups defined by demographic criteria. Detailed linkages to other chapters allow the inclusion of neighbouring disciplines, such as the neurosciences and molecular biology. Contemporary Psychiatry is also unique in including chapters on psychiatric disorders caused by catastrophes, disasters etc. -- aspects totally neglected by normal textbooks. While this book gives an overall view of the state of the art of psychiatric knowledge, it even goes so far as to suggest future perspectives.

Narrative Medicine and Community Based Health Care and Planning

Narrative Medicine and Community Based Health Care and Planning
Author: John W Murphy,Berkeley A. Franz,Jung Min Choi,Karen A. Callaghan
Publsiher: Springer
Total Pages: 136
Release: 2017-09-30
ISBN 10: 3319618571
ISBN 13: 9783319618579
Language: EN, FR, DE, ES & NL

Narrative Medicine and Community Based Health Care and Planning Book Review:

This progressive resource brings the innovative power of narrative medicine to the forefront of community public health care. Chapters describe community involvement across a continuum of control, from health consultants describing problems and suggesting solutions to health committees designing programs and evaluating results. Narrative strategies to this end, including authentic dialogue and community mapping, are examined in the context of public health and fleshed out with examples of different levels of participation by community members. From the respectful collaboration modeled here, the principles of community public health care can potentially expand beyond the immediate community into other social domains on a greater scale. Included in the coverage: · Narratives, local knowledge, and world entry. · Community and narratives. · What is dialogue? · Storylines, causes, and locus of interventions. · Community mapping tells a story. · The politics of storytelling. Narrative Medicine and Community-Based Health Care and Planning gives health psychologists, sociologists, social workers, and public health administrators realistic practical insights for tapping into the unique resources communities and clients have to offer. This is the next step in the evolution of public health, toward large-scale improvements in care delivery, access to and relevance of services, and patient and community outcomes.

Modern Epidemiology

Modern Epidemiology
Author: Kenneth J. Rothman,Sander Greenland,Timothy L. Lash
Publsiher: Lippincott Williams & Wilkins
Total Pages: 776
Release: 2008
ISBN 10: 9780781755641
ISBN 13: 0781755646
Language: EN, FR, DE, ES & NL

Modern Epidemiology Book Review:

The thoroughly revised and updated Third Edition of the acclaimed Modern Epidemiology reflects both the conceptual development of this evolving science and the increasingly focal role that epidemiology plays in dealing with public health and medical problems. Coauthored by three leading epidemiologists, with sixteen additional contributors, this Third Edition is the most comprehensive and cohesive text on the principles and methods of epidemiologic research. The book covers a broad range of concepts and methods, such as basic measures of disease frequency and associations, study design, field methods, threats to validity, and assessing precision. It also covers advanced topics in data analysis such as Bayesian analysis, bias analysis, and hierarchical regression. Chapters examine specific areas of research such as disease surveillance, ecologic studies, social epidemiology, infectious disease epidemiology, genetic and molecular epidemiology, nutritional epidemiology, environmental epidemiology, reproductive epidemiology, and clinical epidemiology.

Artificial Intelligence in Healthcare

Artificial Intelligence in Healthcare
Author: Adam Bohr,Kaveh Memarzadeh
Publsiher: Academic Press
Total Pages: 378
Release: 2020-06-21
ISBN 10: 0128184396
ISBN 13: 9780128184394
Language: EN, FR, DE, ES & NL

Artificial Intelligence in Healthcare Book Review:

Artificial Intelligence (AI) in Healthcare is more than a comprehensive introduction to artificial intelligence as a tool in the generation and analysis of healthcare data. The book is split into two sections where the first section describes the current healthcare challenges and the rise of AI in this arena. The ten following chapters are written by specialists in each area, covering the whole healthcare ecosystem. First, the AI applications in drug design and drug development are presented followed by its applications in the field of cancer diagnostics, treatment and medical imaging. Subsequently, the application of AI in medical devices and surgery are covered as well as remote patient monitoring. Finally, the book dives into the topics of security, privacy, information sharing, health insurances and legal aspects of AI in healthcare. Highlights different data techniques in healthcare data analysis, including machine learning and data mining Illustrates different applications and challenges across the design, implementation and management of intelligent systems and healthcare data networks Includes applications and case studies across all areas of AI in healthcare data

Mobile Computing and Wireless Networks Concepts Methodologies Tools and Applications

Mobile Computing and Wireless Networks  Concepts  Methodologies  Tools  and Applications
Author: Management Association, Information Resources
Publsiher: IGI Global
Total Pages: 2308
Release: 2015-09-30
ISBN 10: 1466687525
ISBN 13: 9781466687523
Language: EN, FR, DE, ES & NL

Mobile Computing and Wireless Networks Concepts Methodologies Tools and Applications Book Review:

We live in a wireless society, one where convenience and accessibility determine the efficacy of the latest electronic gadgets and mobile devices. Making the most of these technologies—and ensuring their security against potential attackers—requires increased diligence in mobile technology research and development. Mobile Computing and Wireless Networks: Concepts, Methodologies, Tools, and Applications brings together a comprehensive range of voices and research in the area of mobile and wireless technologies, exploring the successes and failures, advantages and drawbacks, and benefits and limitations of the technology. With applications in a plethora of different research and topic areas, this multi-volume reference work benefits researchers, service providers, end-users, and information technology professionals. This four-volume reference work includes a diverse array of chapters and authors covering topics such as m-commerce, network ethics, mobile agent systems, mobile learning, communications infrastructure, and applications in fields such as business, healthcare, government, tourism, and more.

Improving Diagnosis in Health Care

Improving Diagnosis in Health Care
Author: National Academies of Sciences, Engineering, and Medicine,Institute of Medicine,Board on Health Care Services,Committee on Diagnostic Error in Health Care
Publsiher: National Academies Press
Total Pages: 473
Release: 2016-01-29
ISBN 10: 0309377692
ISBN 13: 9780309377690
Language: EN, FR, DE, ES & NL

Improving Diagnosis in Health Care Book Review:

Getting the right diagnosis is a key aspect of health care - it provides an explanation of a patient's health problem and informs subsequent health care decisions. The diagnostic process is a complex, collaborative activity that involves clinical reasoning and information gathering to determine a patient's health problem. According to Improving Diagnosis in Health Care, diagnostic errors-inaccurate or delayed diagnoses-persist throughout all settings of care and continue to harm an unacceptable number of patients. It is likely that most people will experience at least one diagnostic error in their lifetime, sometimes with devastating consequences. Diagnostic errors may cause harm to patients by preventing or delaying appropriate treatment, providing unnecessary or harmful treatment, or resulting in psychological or financial repercussions. The committee concluded that improving the diagnostic process is not only possible, but also represents a moral, professional, and public health imperative. Improving Diagnosis in Health Care, a continuation of the landmark Institute of Medicine reports To Err Is Human (2000) and Crossing the Quality Chasm (2001), finds that diagnosis-and, in particular, the occurrence of diagnostic errorsâ€"has been largely unappreciated in efforts to improve the quality and safety of health care. Without a dedicated focus on improving diagnosis, diagnostic errors will likely worsen as the delivery of health care and the diagnostic process continue to increase in complexity. Just as the diagnostic process is a collaborative activity, improving diagnosis will require collaboration and a widespread commitment to change among health care professionals, health care organizations, patients and their families, researchers, and policy makers. The recommendations of Improving Diagnosis in Health Care contribute to the growing momentum for change in this crucial area of health care quality and safety.

Modern Issues and Methods in Biostatistics

Modern Issues and Methods in Biostatistics
Author: Mark Chang
Publsiher: Springer Science & Business Media
Total Pages: 307
Release: 2011-07-15
ISBN 10: 144199842X
ISBN 13: 9781441998422
Language: EN, FR, DE, ES & NL

Modern Issues and Methods in Biostatistics Book Review:

Classic biostatistics, a branch of statistical science, has as its main focus the applications of statistics in public health, the life sciences, and the pharmaceutical industry. Modern biostatistics, beyond just a simple application of statistics, is a confluence of statistics and knowledge of multiple intertwined fields. The application demands, the advancements in computer technology, and the rapid growth of life science data (e.g., genomics data) have promoted the formation of modern biostatistics. There are at least three characteristics of modern biostatistics: (1) in-depth engagement in the application fields that require penetration of knowledge across several fields, (2) high-level complexity of data because they are longitudinal, incomplete, or latent because they are heterogeneous due to a mixture of data or experiment types, because of high-dimensionality, which may make meaningful reduction impossible, or because of extremely small or large size; and (3) dynamics, the speed of development in methodology and analyses, has to match the fast growth of data with a constantly changing face. This book is written for researchers, biostatisticians/statisticians, and scientists who are interested in quantitative analyses. The goal is to introduce modern methods in biostatistics and help researchers and students quickly grasp key concepts and methods. Many methods can solve the same problem and many problems can be solved by the same method, which becomes apparent when those topics are discussed in this single volume.

Racial and Ethnic Disparities in Health and Health Care

Racial and Ethnic Disparities in Health and Health Care
Author: Elene V. Metrosa
Publsiher: Nova Publishers
Total Pages: 248
Release: 2006
ISBN 10: 9781600212680
ISBN 13: 1600212689
Language: EN, FR, DE, ES & NL

Racial and Ethnic Disparities in Health and Health Care Book Review:

It is generally conceded that there are significant disparities in health and health care based on a person's racial and ethnic background. Infant mortality rates for black babies remain nearly two-and-one-half times higher than for whites. The life expectancy for black men and women remains at nearly one decade fewer years of life compared with their white counterparts. Rates of death attributable to heart disease, stroke, prostate and breast cancer remain much higher in black populations. Diabetes disease rates are more than 30 percent higher among Native Americans and Hispanics than among whites. Minorities remain grossly under-represented in the health professions workforce relative to their proportions in the population. In addition, despite a large and growing body of scientific evidence, many patients and providers remain unaware that racial and ethnic health care disparities are a problem and perceptions about health care inequalities vary between minorities and whites. closing the disparity gap. This book presents new research focusing on these disparities.

The Bloomsbury Companion to Contemporary Philosophy of Medicine

The Bloomsbury Companion to Contemporary Philosophy of Medicine
Author: James A. Marcum
Publsiher: Bloomsbury Publishing
Total Pages: 432
Release: 2016-12-15
ISBN 10: 1474233023
ISBN 13: 9781474233026
Language: EN, FR, DE, ES & NL

The Bloomsbury Companion to Contemporary Philosophy of Medicine Book Review:

A definitive and authoritative guide to a vibrant and growing discipline in current philosophy, The Bloomsbury Companion to Contemporary Philosophy of Medicine presents an overview of the issues facing contemporary philosophy of medicine, the research methods required to understand them and a trajectory for the discipline's future. Written by world leaders in the discipline, this companion addresses the ontological, epistemic, and methodological challenges facing philosophers of medicine today, from the debate between evidence-based and person-centered medicine, medical humanism, and gender medicine, to traditional issues such as disease, health, and clinical reasoning and decision-making. Practical and forward-looking, it also includes a detailed guide to research sources, a glossary of key terms, and an annotated bibliography, as well as an introductory survey of research methods and discussion of new research directions emerging in response to the rapid changes in modern medicine. “Philosophy needs medicine', Hillel Braude argues, 'to become more relevant'. By showing how modern medicine provides philosophers with a rich source of material for investigating issues facing contemporary society, The Bloomsbury Companion to Contemporary Philosophy of Medicine introduces the opportunities medicine offers philosophers together with the resources and skills required to contribute to contemporary debates and discussions.

Modern Epidemiology

Modern Epidemiology
Author: Timothy L. Lash,Tyler J. VanderWeele,Sebastien Haneause,Kenneth Rothman
Publsiher: Lippincott Williams & Wilkins
Total Pages: 1340
Release: 2020-12-11
ISBN 10: 1975166280
ISBN 13: 9781975166281
Language: EN, FR, DE, ES & NL

Modern Epidemiology Book Review:

Now in a fully revised Fourth Edition, Modern Epidemiology remains the gold standard text in this complex and evolving field. This edition continues to provide comprehensive coverage of the principles and methods for the design, analysis, and interpretation of epidemiologic research. Featuring a new format allowing space for margin notes, this edition • Reflects both the conceptual development of this evolving science and the increasing role that epidemiology plays in improving public health and medicine. • Features new coverage of methods such as agent-based modeling, quasi-experimental designs, mediation analysis, and causal modeling. • Updates coverage of methods such as concepts of interaction, bias analysis, and time-varying designs and analysis. • Continues to cover the full breadth of epidemiologic methods and concepts, including epidemiologic measures of occurrence and effect, study designs, validity, precision, statistical interference, field methods, surveillance, ecologic designs, and use of secondary data sources. • Includes data analysis topics such as Bayesian analysis, probabilistic bias analysis, time-to-event analysis, and an extensive overview of modern regression methods including logistic and survival regression, splines, longitudinal and cluster-correlated/hierarchical data analysis, propensity scores and other scoring methods, and marginal structural models. • Summarizes the history, specialized aspects, and future directions of topical areas, including among others social epidemiology, infectious disease epidemiology, genetic and molecular epidemiology, psychiatric epidemiology, injury and violence epidemiology, and pharmacoepidemiology.

Genomics and Health in the Developing World

Genomics and Health in the Developing World
Author: Dhavendra Kumar
Publsiher: Oxford University Press
Total Pages: 1501
Release: 2012-06-14
ISBN 10: 0195374754
ISBN 13: 9780195374759
Language: EN, FR, DE, ES & NL

Genomics and Health in the Developing World Book Review:

This book is designed to be the first major text to discuss advances in medical genetics in the developing world.

Advances in microbial food safety

Advances in microbial food safety
Author: G.C. Barker
Publsiher: Elsevier Inc. Chapters
Total Pages: 560
Release: 2013-07-31
ISBN 10: 0128089806
ISBN 13: 9780128089804
Language: EN, FR, DE, ES & NL

Advances in microbial food safety Book Review:

Biotracing is a method for investigating food chain contamination events that concentrates on identification of probable sources. Biotracing is complementary to existing food safety assessments and is related to similar investigation processes in molecular epidemiology and forensic science. This chapter describes the background to biotracing, identifies important elements and describes an emerging methodology. In addition the chapter includes a review of a detailed biotracing model for Staphylococcus aureus in processed milk. The chapter concludes by highlighting options for food chain integration and includes some possibilities for future developments.

Contemporary Masculinities

Contemporary Masculinities
Author: Brendan Gough
Publsiher: Springer
Total Pages: 92
Release: 2018-04-19
ISBN 10: 3319788191
ISBN 13: 9783319788197
Language: EN, FR, DE, ES & NL

Contemporary Masculinities Book Review:

This book assesses the construction of masculinities in relation to appearance, embodiment and emotions by drawing on perspectives in psychology, sociology, gender studies and public health. Brendan Gough questions conventional assumptions about masculinity and men’s health and responds to recent trends in critical studies of masculinities which discuss ‘positive’ or ‘healthy’ masculine identities. The book showcases discursively inflected qualitative research using data sources where men’s own accounts are prioritised: in-depth interviews and online discussion forums. Chapters discuss men’s appearance concerns and activities and examine male mental health, focusing on vulnerability and its management. Current trends and key concepts, including intersectionality, inequalities and embodiment are also considered throughout. This book will appeal to students and academics within social sciences and humanities interested in gender issues in general and masculinity in particular.

Issues in Healthcare Communication and Information Technology 2011 Edition

Issues in Healthcare Communication and Information Technology  2011 Edition
Author: Anonim
Publsiher: ScholarlyEditions
Total Pages: 241
Release: 2012-01-09
ISBN 10: 1464967415
ISBN 13: 9781464967412
Language: EN, FR, DE, ES & NL

Issues in Healthcare Communication and Information Technology 2011 Edition Book Review:

Issues in Healthcare Communication and Information Technology: 2011 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Healthcare Communication and Information Technology. The editors have built Issues in Healthcare Communication and Information Technology: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Healthcare Communication and Information Technology in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Issues in Healthcare Communication and Information Technology: 2011 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at

Critical Perspectives on Racial and Ethnic Differences in Health in Late Life

Critical Perspectives on Racial and Ethnic Differences in Health in Late Life
Author: National Research Council,Division of Behavioral and Social Sciences and Education,Committee on Population,Panel on Race, Ethnicity, and Health in Later Life
Publsiher: National Academies Press
Total Pages: 752
Release: 2004-10-16
ISBN 10: 0309092116
ISBN 13: 9780309092111
Language: EN, FR, DE, ES & NL

Critical Perspectives on Racial and Ethnic Differences in Health in Late Life Book Review:

In their later years, Americans of different racial and ethnic backgrounds are not in equally good--or equally poor--health. There is wide variation, but on average older Whites are healthier than older Blacks and tend to outlive them. But Whites tend to be in poorer health than Hispanics and Asian Americans. This volume documents the differentials and considers possible explanations. Selection processes play a role: selective migration, for instance, or selective survival to advanced ages. Health differentials originate early in life, possibly even before birth, and are affected by events and experiences throughout the life course. Differences in socioeconomic status, risk behavior, social relations, and health care all play a role. Separate chapters consider the contribution of such factors and the biopsychosocial mechanisms that link them to health. This volume provides the empirical evidence for the research agenda provided in the separate report of the Panel on Race, Ethnicity, and Health in Later Life.

Developmental Psychopathology Theory and Method

Developmental Psychopathology  Theory and Method
Author: Dante Cicchetti
Publsiher: John Wiley & Sons
Total Pages: 1176
Release: 2015-12-22
ISBN 10: 111912543X
ISBN 13: 9781119125433
Language: EN, FR, DE, ES & NL

Developmental Psychopathology Theory and Method Book Review:

The seminal reference for the latest research in developmental psychopathology Developmental Psychopathology is a four-volume compendium of the most complete and current research on every aspect of the field. Volume One: Theory and Method focuses on the theoretical and empirical work that has contributed to dramatic advancements in understanding of child and adult development, including findings in the areas of genetics and neurobiology, as well as social and contextual factors. Now in its third edition, this comprehensive reference has been fully updated to reflect the current state of the field and its increasingly multilevel and interdisciplinary nature and the increasing importance of translational research. Contributions from expert researchers and clinicians provide insight into how multiple levels of analysis may influence individual differences, the continuity or discontinuity of patterns, and the pathways by which the same developmental outcomes may be achieved. Advances in developmental psychopathology have burgeoned since the 2006 publication of the second edition ten years ago, and keeping up on the latest findings in multiple avenues of investigation can be burdensome to the busy professional and researcher from psychology and related fields. This reference solves the problem by collecting the best of the best, as edited by Dante Cicchetti, a recognized leader in the field, into one place, with a logical organization designed for easy reference. Get up to date on the latest research from the field Explore new models, emerging theory, and innovative approaches Learn new technical analysis and research design methods Understand the impact of life stage on mental health The complexity of a field as diverse as developmental psychopathology deepens with each emerging theory and new area of study, as made obvious by the exciting findings coming out of institutions and clinics around the world. Developmental Psychopathology Volume One: Theory and Method brings these findings together into a cohesive, broad-reaching reference.

Statistics in the Health Sciences

Statistics in the Health Sciences
Author: Albert Vexler,Alan Hutson
Publsiher: CRC Press
Total Pages: 398
Release: 2018-01-19
ISBN 10: 1315293757
ISBN 13: 9781315293752
Language: EN, FR, DE, ES & NL

Statistics in the Health Sciences Book Review:

"This very informative book introduces classical and novel statistical methods that can be used by theoretical and applied biostatisticians to develop efficient solutions for real-world problems encountered in clinical trials and epidemiological studies. The authors provide a detailed discussion of methodological and applied issues in parametric, semi-parametric and nonparametric approaches, including computationally extensive data-driven techniques, such as empirical likelihood, sequential procedures, and bootstrap methods. Many of these techniques are implemented using popular software such as R and SAS."— Vlad Dragalin, Professor, Johnson and Johnson, Spring House, PA "It is always a pleasure to come across a new book that covers nearly all facets of a branch of science one thought was so broad, so diverse, and so dynamic that no single book could possibly hope to capture all of the fundamentals as well as directions of the field. The topics within the book’s purview—fundamentals of measure-theoretic probability; parametric and non-parametric statistical inference; central limit theorems; basics of martingale theory; Monte Carlo methods; sequential analysis; sequential change-point detection—are all covered with inspiring clarity and precision. The authors are also very thorough and avail themselves of the most recent scholarship. They provide a detailed account of the state of the art, and bring together results that were previously scattered across disparate disciplines. This makes the book more than just a textbook: it is a panoramic companion to the field of Biostatistics. The book is self-contained, and the concise but careful exposition of material makes it accessible to a wide audience. This is appealing to graduate students interested in getting into the field, and also to professors looking to design a course on the subject." — Aleksey S. Polunchenko, Department of Mathematical Sciences, State University of New York at Binghamton This book should be appropriate for use both as a text and as a reference. This book delivers a "ready-to-go" well-structured product to be employed in developing advanced courses. In this book the readers can find classical and new theoretical methods, open problems and new procedures. The book presents biostatistical results that are novel to the current set of books on the market and results that are even new with respect to the modern scientific literature. Several of these results can be found only in this book.