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Irreversible Damage is an exploration of a mystery: Why, in the last decade, has the diagnosis "gender dysphoria," transformed from a vanishingly rare affliction, applying almost exclusively to boys and men, to an epidemic among teenage girls? Author Abigail Shrier presents shocking statistics and stories from real families to show that America and the West have become fertile ground for a "transgender craze" that has nothing to do with real gender dysphoria and everything to do with our cultural frailty. Teenage girls are taking courses of testosterone and disfiguring their bodies. Parents are undermined; experts are over-relied upon; dissenters in science and medicine are intimidated; free speech truckles under renewed attack; socialized medicine bears hidden consequences; and an intersectional era has arisen in which the desire to escape a dominant identity encourages individuals to take cover in victim groups. Every person who has ever had a skeptical thought about the sudden rush toward a non-binary future but been afraid to express it—this book is for you.
In this first book of a series on contemporary social justice activism, Katie, the youngest daughter of two Mexican-American lawyers, has lived a sheltered upbringing in a wealthy Paradise Valley neighborhood of Phoenix. Life there never prepared her for the upheaval and tragedy that was to surround her and many of her loved ones. Katie learns that changes affecting her life were instigated by forces and people far removed from her, and whose greed for political and financial gain means more to them than the lives they sacrificed along the way. Motivated by these events and armed with the understanding that history shapes the present and will shape the future, Katie, surrounded by loyal friends, becomes a social activist whose ultimate achievement could changes the lives and the future of hundreds of thousands of people or leave her destitute or dead.
Chemical Resistance of Thermoplastics is a unique reference work, providing a comprehensive cross-referenced compilation of chemical resistance data that explains the effect of thousands of exposure media on the properties and characteristics of commodity thermoplastics. The two volumes cover thermoplastics grouped within the following parts: - Acrylic Polymers and Copolymers - Acrylonitrile Polymers - Cellulosics Polymers - Ionomers - Olefinic Polymers - Polyacetals - Polyacetals - Polyamides - Polycarbonates - Polyesters - Polyurethanes - Polycarbonates - Styrene Copolymers - Styrene Copolymers - Vinyl Chloride Polymers - Vinyl Polymers The single most comprehensive data source covering the chemical resistance properties of high consumption volume commercial thermoplastics A rating number is provided for each test, summarizing the effect of the exposure medium on the given thermoplastic The data covered in the two volumes is also provided as an online publication offering extended navigation and search features
Oxygen free radicals and other reactive oxygen species are being postulated as causal agents in an increasing number of pathological conditions. Indeed, some investigators are suggesting that highly destructive reactive oxygen species are the final common path lead ing to tissue damage following a wide variety of insults including trauma, hypoxia, ischemia, hyperoxia, radiation, some toxins, and even strenuous athletic pursuits. But, as Robert Floyd points out, "Proof of the importance of oxygen free radicals and the oxidative damage they initiate depend on unequivocal evidence for the pres ence of free radicals and a clear association of their formation with the induction of the dysfunction of pathological conditions. " Since such proof does not come easily, there have been and will continue to be many controversies regarding the role played by reactive oxygen species in tissue damage. There have been many recent reviews of the chemistry and pos sible role of reactive oxygen species in many types of organ dys functions, tissue damage, degenerative diseases, and aging. This book is not such a review. Rather it presents for a diverse audience of physical-organic chemists, biochemists, medical researchers, and other investigators of pathophysiology, discussions of a variety of is sues important for understanding reactive oxygen species and their role in tissue damage.
This volume features key presentations from the 6th International Congress of Autoimmunity. The International Congress of Autoimmunity has become established as one of the major meetings in the field of immunology, with presentations covering every aspect of basic research in the hopes of clarifying pathogenesis of autoimmune disease as well as providing information on the latest innovations in biological and other modes of treatment. The goal of this volume is to present cutting edge research that focuses in particular on newer diagnostic tools and newer therapies for human autoimmune disease. NOTE: Annals volumes are available for sale as individual books or as a journal. For information on institutional journal subscriptions, please visit www.blackwellpublishing.com/nyas. ACADEMY MEMBERS: Please contact the New York Academy of Sciences directly to place your order (www.nyas.org). Members of the New York Academy of Science receive full-text access to the Annals online and discounts on print volumes. Please visit http://www.nyas.org/MemberCenter/Join.aspx for more information about becoming a member.
Current Topics in Occupational Epidemiology is an in-depth study of the contemporary issues and emerging themes in the field. Divided into nine sections the book discusses how traditional methods can be used to study new" occupational diseases such as epidemiological studies of older workers, and aid understanding of the "older" topics including morbidity and mortality among coal workers. Trends in society have allowed occupational epidemiological methods to be expanded to cover issues such as the ageing workforce, return to work after illness, and the migration of workers. These issues as well as new data sources such as surveillance systems are discussed in topic specific chapters. Written by leading international experts in the field, Current Topics in Occupational Epidemiology provides a comprehensive look at the current areas of interest and will be essential reading for epidemiologists, statisticians, exposure assessment scientists, physicians, and policymakers."
The thoroughly updated Second Edition of this popular and widely used pocket reference guides the trauma team through every aspect of patient care after injury--from prehospital care, to resuscitation, treatment of specific organ injuries, priorities in intensive care, and management of special situations. Designed for rapid, on-the-spot information retrieval, The Trauma Manual, Second Edition will be a staple reference in emergency departments. Flow charts, algorithms, sequential lists, and tables throughout facilitate quick clinical decision-making. More than 100 illustrations demonstrate specific injuries and procedures. Appendices include injury scales, tetanus prophylaxis recommendations, commonly used formulae and values, and frequently used forms. This edition includes a new chapter on commonly missed injuries and common pitfalls.
Many people believe that everyone who uses heroin is addicted. In fact, this is true of only about 20 percent of heroin users. By clearing up common misconceptions like these, this book provides information that can save the lives of people using the drug. The author recounts heroin's history, details its chemistry, tells what users need to know to avoid addiction, and demystifies the life of a user: from buying to administering to detoxing and staying clean.
This Dictionary provides over 75,000 entries covering all areasof chemistry, such as Chemical Biology, Biochemistry,Biotechnology, and Nanochemistry, plus relevant terms in relatedspheres of expertise. In order to prepare this SecondEdition, the First Edition was completely revised, and over 35,000new terms were added. This new edition will continue to be theDictionary that chemists, educators, students, translators, andthose working in English and Spanish in chemistry and associatedfields have been trusting since the First Edition was published in1998.
A comprehensive guide to vitreoretinal surgery, beginning with an introduction to the principles and techniques of vitrectomy, then discusses retinal detachment, diabetic retinopathy, macular surgery, trauma and endophthalmitis. A separate chapter is dedicated to paediatric vitreoretinal surgery. Contributions from international specialists, and almost 400 images and illustrations including schematic drawings, clinical photographs, fluorescein angiograms and OCT images.
"This volume in the Surgical Techniques in Opthalmology series offers step-by-step authoritative guidance on how to successfully perform basic retina and vitreous surgery for retinal detachments and epiretinal membranes, as well as more involved procedures such as complex scleral buckle for ROP and vitrectomy surgery for PVR, ROP, and tumors. Best of all, a wealth of full-color illustrations and photographs, a concise format that complements the commentary, and the surgical procedures on the accompanying DVD-ROM show you exactly how to proceed." --Book Jacket.
|Author||: United States. National Bureau of Standards,American Society for Testing and Materials,United States. Office of Naval Research,United States. Energy Research and Development Administration|
|Total Pages||: 409|
|ISBN 13||: UIUC:30112007694356|
|Language||: EN, FR, DE, ES & NL|
The Novartis Foundation Series is a popular collection of the proceedings from Novartis Foundation Symposia, in which groups of leading scientists from a range of topics across biology, chemistry and medicine assembled to present papers and discuss results. The Novartis Foundation, originally known as the Ciba Foundation, is well known to scientists and clinicians around the world.
Biomarkers for Antioxidant Defense and Oxidative Damage: Principles and Practical Applications critically evaluates the basic concepts and methodologies of conventional biomarkers as well as current state-of-the-art assays for measuring antioxidant activity/oxidative stress and their practical applications. . Biomarkers for Antioxidant Defense and Oxidative Damage: Principles and Practical Applications will be of a great interest to scientists who are involved in basic research on oxidation, applied scientists evaluating the effects of nutraceuticals or pharmaceutical compounds on antioxidant activity/oxidative stress, and physicians who want to understand the degree of oxidative damage in patients with certain chronic diseases. Discovering sensitive and specific biomarkers for systemic oxidative damage is essential to understand the role of oxidative stress in human disease. Once these roles are clearly understood, we are able to identify novel drug and nutraceutical targets. This volume goes beyond conventional analytical methods of measuring overall antioxidant activity and provides insight to the discovery of biomarkers that reveal information on specific areas of oxidative stress. Contributed by an international list of experts, Biomarkers for Antioxidant Defense and Oxidative Damage: Principles and Practical Applications describes both conventional biomarkers and recent developments in this area. Special Features: Discusses conventional biomarkers as well as recent advances for measuring antioxidants and oxidative stress Biomarkers for lipid peroxidation: isoprostane, hydroxyloctadecaenoic acid, oxysterols, and reactive carbonyl species from lipid peroxidation Biomarkers for protein oxidation: carbonylation, tyrosine oxidation, ubiquitin-conjugation Biomarkers for DNA oxidative damage: comet assay, hydroxylated nucleotides, and exocylcic DNA adducts Recently developed biomarkers from cutting-edge technology
Now in its 7th edition, this popular, must-have text remains the only encyclopedic resource for veterinary internal medical problems. The internationally acclaimed "gold standard" offers unparalleled coverage of pathophysiology, diagnosis, and treatment of diseases affecting dogs and cats, as well as the latest information on the genome, clinical genomics, euthanasia, innocent heart murmurs, hyperbaric medicine, home prepared and raw diets, obesity, botulism, artificial pacing of the heart, cancer vaccines, and more. The 7th edition combines the convenience of a two-volume printed textbook with the enhanced functionality of an Expert Consult website that enables you to electronically search your entire book and study more efficiently. With instant access to the most reliable information available, you’ll always be at the forefront of veterinary care! Fully searchable online text provides fast, easy access to the most reliable information in the field. More than 150 clinical algorithms throughout the text aid in disease-identification and decision-making. Expanded online chapter content enhances your understanding through additional text, illustrations, tables, and boxes. Hyperlinked client information sheets streamline reference of specific conditions and enhance communication with clients. Extensive online reference list directs you to full-text PubMed abstracts for additional research. Thoroughly updated and expanded content, including 90 new chapters, addresses the latest developments across the full spectrum of small animal care. Companion Expert Consult website enhances your learning experience with the ability to search the entire electronic text instantly for easy reference. Expert Consult also gives you instant access to: More than 150 procedural videos that guide you step-by-step through essential procedures. Audio files that help you identify heart abnormalities by their sound.
Even at the beginning of the new millenium the rare earths still remain, to a certain extent, a mystery. The chapters in this volume will help to unravel some of these. In the filling of the 4f electronic orbitals the lanthanides defy the elementary aufbau principle that underlies the periodic sequence of the elements, and the authors of the first chapter introduce the readers to the basic physics of the orbital collapse leading to that failure. Furthermore an explanation is offered in terms of double-well potentials. The phenomenon is illustrated using the valence transitions observed in some of the rare earth atoms, including Sm group metals and the higher oxides of cerium, praseodymium and terbium. In the second chapter the synthesis and structure of the many types of rare earth halides are described. They have been described as simple, complex, binary, ternary and multinuclear complex, and other categories needed to deal with the most studied of the rare earth compounds. The structure types are skillfully illustrated to show the elementary architecture of each type. In chapter three the authors discuss the science and applications of rare earth super ionic conductors as solid electrolytes. Conduction by oxygen and fluorine anions as well as hydrogen and other cations associated with these electrolytes is emphasized. They deal with extrinsic and intrinsic types together with their associated structures and structural types including structural defects. The chapter concludes with an outline of the many applications of solid electrolytes. Chapter four introduces the reader to the principles that underlie thermoluminescence and its application to dosimetry and provides detailed information on the R-activated phosphors that support dosimetry. This is a selective review of detailed literature based on the areas making most progress. The final chapter elaborates on the data gained by the studies and interpretation around the analytical separation of the individual rare earth elements utilizing chromatographic techniques. The authors describe the fundamental chemistry that underpins contemporary analytical separation techniques for lanthanide separation and analysis. This is done after a description of the rich assortment of separation methods in use has been introduced.