Biomaterials and Immune Response

Biomaterials and Immune Response
Author: Nihal Engin Vrana
Publsiher: CRC Press
Total Pages: 249
Release: 2018-07-20
ISBN 10: 1351377558
ISBN 13: 9781351377553
Language: EN, FR, DE, ES & NL

Biomaterials and Immune Response Book Review:

The interactions of the biomaterials with the host immune system is crucial for their functionality. This book aims to provide the reader with a better understanding of the role of the immune system in biomaterial applications. For this end, the book has dedicated chapters for i) explaining immune cells taking part in immune response to biomaterials/immune systems interface; ii) the effect of biomaterial shape, form and physicochemical properties on the response of immune system; iii) biofilm formation on implanted materials as a failure of immune system/biomaterial interactions; iv) tissue-specific effects of immune response and its consequences for tissue engineering and regenerative medicine; v) immune reaction in a clinical context (periodontology). In the field of biomaterials there are significant advances in using immunomodulation techniques to improve the success rates of implantable materials. For better understanding of such techniques it is required to have a full grasp of the biomaterial–immune system interactions. This would greatly enhance the understanding of why the human body reacts to implants in a certain way and how to improve the clinical outcomes by developing immune-instructive biomaterials. Provides keen insight into biomaterial–immune cell interactions Presents an explanation of state-of-the-art methodologies in immunomodulation Offers a concise and simple-to-understand treatment of biomaterial–immune cell interactions for materials scientists in a biology heavy topic Explores a comprehensive overview of biomaterial related complications Provides extensive references at the end of each chapter to enhance study for this very hot research area

Immunomodulatory Biomaterials

Immunomodulatory Biomaterials
Author: Stephen F. Badylak,Jennifer Elisseeff
Publsiher: Woodhead Publishing
Total Pages: 294
Release: 2021-07-30
ISBN 10: 0128214562
ISBN 13: 9780128214565
Language: EN, FR, DE, ES & NL

Immunomodulatory Biomaterials Book Review:

Biomaterials have existed for millennia as mechanical replacement structures following disease or injury. Biomaterial design has changed markedly from structural support with an “inert immune profile as the primary objective to designs that elicit an integrative local tissue response and a pro-repair immune cell phenotype. Immunomodulatory Biomaterials: Regulating the Immune Response with Biomaterials to Affect Clinical Outcome offers a single, comprehensive reference on biomaterials for modulation of the host response, for materials scientists, tissue engineers and those working in regenerative medicine. This book details methods, materials and strategies designed to regulate the host immune response following surgical implantation and thus facilitate specific local cell infiltration and tissue deposition. There has been a dramatic transformation in our understanding of the role of the immune system, both innate and adaptive; these changes include recognition of the plasticity of immune cells, especially macrophages, cross-talk between the immune system and stem cells, and the necessity for in situ transition between inflammatory and regulatory immune cell phenotypes. The exploitation of these findings and the design and manufacture of new biomaterials is occurring at an astounding pace. There is currently no book directed at the interdisciplinary principles guiding the design, manufacture, testing, and clinical translation of biomaterials that proactively regulate the host tissue immune response. The challenge for academia, industry, and regulatory agencies to encourage innovation while assuring safety and maximizing efficacy has never been greater. Given the highly interdisciplinary requirements for the design, manufacture and use of immunomodulatory biomaterials, this book will prove a useful single resource across disciplines. Holistically covers the design, manufacture, testing, and clinical translation of biomaterials that proactively regulate the host tissue immune response Provides a single reference for understanding and utilizing the host response in biomaterials design An international collaboration of leading researchers in the field offering a novel insight into this fast-growing area

Cellular Response to Biomaterials

Cellular Response to Biomaterials
Author: Lucy Di Silvio
Publsiher: Elsevier
Total Pages: 648
Release: 2008-12-22
ISBN 10: 184569547X
ISBN 13: 9781845695477
Language: EN, FR, DE, ES & NL

Cellular Response to Biomaterials Book Review:

The response of cells to biomaterials is critical in medical devices. Traditionally inert biomaterials were used to minimise the reaction in cells in contact with the material. However, it has been realised that specific cell responses may be beneficial in such areas as encouraging adhesion, healing or cell multiplication. Cellular response to biomaterials discusses the response of cells to a wide range of biomaterials targeted at specific medical applications. Part one discusses cell responses to a variety of polymers and ceramics with chapters on such topics as degradable polymers and biocompatibility. Part two covers cell responses and regenerative medicine with coverage of themes such as vascular grafts, nerve repair and Bioglass®. Part three examines the effect of surfaces and proteins on cell response. Specific chapters review nano-engineered surfaces, the influence of plasma proteins on bone cell adhesion and surface modification of titanium implants. With its distinguished editor and team of international contributors, Cellular response to biomaterials is an essential read for those researching or studying medical devices in industry and academia. Examines the response of cells to a wide range of biomaterials targeted at specific medical applications Discusses cell responses and regenerative medicine with specific chapters on vascular grafts and nerve repair Assesses the effect of surfaces and proteins on cell response including the influence of plasma proteins on cell adhesion and surface modification of titanium implants

Bioactive Materials for Bone Regeneration

Bioactive Materials for Bone Regeneration
Author: Jiang Chang,Xingdong Zhang,Kerong Dai
Publsiher: Academic Press
Total Pages: 248
Release: 2020-02-28
ISBN 10: 0128135042
ISBN 13: 9780128135044
Language: EN, FR, DE, ES & NL

Bioactive Materials for Bone Regeneration Book Review:

Bioactive Materials for Bone Regeneration summarizes research advances on the topic, including sections on the characteristics of biomaterial-induced microenvironments, interactions of bioactive materials with stem cells and tissues, and the immunomodulatory microenvironment induced by biomaterials and its effects on osteogenesis. As the regeneration of large-size bone tissue defects represents a significant clinical challenge, this book demonstrates how new biomaterials with specific chemical and physical characteristics may interact with the host and create a unique micro-environment that actively facilitates stem cell differentiation along a specific lineage, thus stimulating tissue regeneration. Provides readers with the latest research developments in the fabrication techniques of bioactive materials for tissue regeneration and tissue engineering applications Presents the latest research advancements on how bioactive materials interact with the host and induce micro-environments for stem cell differentiation, immunomodulation and tissue regeneration Covers the methods, strategies, principle and mechanisms on constructing beneficial biomaterial microenvironments

Adverse Reactions to Biomaterials State of the Art in Biomaterial Risk Assessment Immunomodulation and In Vitro Models for Biomaterial Testing

Adverse Reactions to Biomaterials  State of the Art in Biomaterial Risk Assessment  Immunomodulation and In Vitro Models for Biomaterial Testing
Author: Nihal Engin Vrana,Amir M. Ghaemmaghami,Pinar Zorlutuna
Publsiher: Frontiers Media SA
Total Pages: 137
Release: 2019-05-15
ISBN 10: 2889458229
ISBN 13: 9782889458226
Language: EN, FR, DE, ES & NL

Adverse Reactions to Biomaterials State of the Art in Biomaterial Risk Assessment Immunomodulation and In Vitro Models for Biomaterial Testing Book Review:

Adverse immune reactions to biomaterials are important bottlenecks for translation of novel biomaterials for clinical use. Moreover, recent advances in highthrough-put biomaterial discovery and synthetic biology, while providing exciting new veues, also significantly increases potential risks related to the in vivo reactions to these new materials. For example, the novel materials might have unintended biological activities due to their natural building blocks. In this perspective, biomaterial field needs i) better understanding of cell/biomaterial interactions at systems level; ii) development of new analysis and testing tools for advanced risk assessment iii) tools and technologies for modulating reactions to biomaterials and iv) advanced in vitro models for understanding and testing of reactions to biomaterials. In the following collection of articles you will find examples of such systems,together with comprehensive reviews of current developments in in vitro model systems. The collection also contains articles that elucidate the immune reaction to biomaterials in vitro and in vitro.

Extracellular Vesicles

Extracellular Vesicles
Author: Dr Wojciech Chrzanowski,Professor Chwee Teck Lim,Dr Sally Yunsun Kim
Publsiher: Royal Society of Chemistry
Total Pages: 344
Release: 2021-10-29
ISBN 10: 178801894X
ISBN 13: 9781788018944
Language: EN, FR, DE, ES & NL

Extracellular Vesicles Book Review:

Extracellular and biofluids vesicles (EVs) are highly specialised yet ubiquitous nanoscale messengers secreted by cells. With the development of stem cell engineering, EVs promise to deliver next generation tools in regenerative medicine and tissue engineering, as well as in diagnostics. A vibrant and promising field, this book provides the first resource to the field. Covering basic cell biology, including EV production and intracellular communication, this book will provide material scientists and engineers with a foundation to the necessary biology. The reader will then learn about the isolation of extracellular vesicles their physicochemical characterisation and therapeutic application of EVs in regenerative medicine as well as their potential as biomarkers in medical diagnostic. This book will also discuss the regulatory landscape of EVs. Bridging cell biology, biomaterials, biophysics and biomedical engineering the content of this book is written with a broad interdisciplinary audience in mind. Researchers, new and established will find this a must-have on their shelf.

Tissue Engineering

Tissue Engineering
Author: Clemens Van Blitterswijk,Jan De Boer
Publsiher: Academic Press
Total Pages: 896
Release: 2014-12-10
ISBN 10: 0124202101
ISBN 13: 9780124202108
Language: EN, FR, DE, ES & NL

Tissue Engineering Book Review:

Tissue Engineering is a comprehensive introduction to the engineering and biological aspects of this critical subject. With contributions from internationally renowned authors, it provides a broad perspective on tissue engineering for students coming to the subject for the first time. In addition to the key topics covered in the previous edition, this update also includes new material on the regulatory authorities, commercial considerations as well as new chapters on microfabrication, materiomics and cell/biomaterial interface. Effectively reviews major foundational topics in tissue engineering in a clear and accessible fashion Includes state of the art experiments presented in break-out boxes, chapter objectives, chapter summaries, and multiple choice questions to aid learning New edition contains material on regulatory authorities and commercial considerations in tissue engineering

Handbook of Biomaterials Biocompatibility

Handbook of Biomaterials Biocompatibility
Author: Masoud Mozafari
Publsiher: Woodhead Publishing
Total Pages: 758
Release: 2020-06-17
ISBN 10: 0081029683
ISBN 13: 9780081029688
Language: EN, FR, DE, ES & NL

Handbook of Biomaterials Biocompatibility Book Review:

Handbook of Biomaterials Biocompatibility is a systematic reference on host response to different biomaterials, taking into account their physical, mechanical and chemical properties. The book reviews recent progress in the design and study of biomaterials biocompatibility, along with current understanding on how to control immune system response. Sections provide the fundamental theories and challenges of biomaterials biocompatibility, the role of different biomaterials physicochemical surface properties on cell responses, cell responses to different physicochemical properties of polymers, ceramics, metals, carbons and nanomaterials, and biomaterials in different tissues, such as the cardiac, nervous system, cartilage and bone. This resource will be suitable for those working in the fields of materials science, regenerative engineering, medicine, medical devices and nanotechnology. Reviews the fundamental theories and challenges of biomaterials biocompatibility, including an overview of the standards and regulations Provides an overview on the cellular and molecular mechanisms involved in host responses to biomaterials Systematically looks at cellular response and tissue response to a wide range of biomaterials, including polymers, metals, ceramics, alloys and nanomaterials

The Immune Response to Implanted Materials and Devices

The Immune Response to Implanted Materials and Devices
Author: Bruna Corradetti
Publsiher: Springer
Total Pages: 241
Release: 2016-11-30
ISBN 10: 3319454331
ISBN 13: 9783319454337
Language: EN, FR, DE, ES & NL

The Immune Response to Implanted Materials and Devices Book Review:

This book provides a comprehensive overview of the cascade of events activated in the body following the implant of biomaterials and devices. It is one of the first books to shed light on the role of the host immune response on therapeutic efficacy, and reviews the state-of-the-art for both basic science and medical applications. The text examines advantages and disadvantages of the use of synthetic versus natural biomaterials. Particular emphasis is placed on the role of biomimicry in the development of smart strategies able to modulate infiltrating immune cells, thus reducing side effects (such as acute and chronic inflammation, fibrosis and/or implant rejection) and improving the therapeutic outcome (healing, tissue restoration). Current cutting-edge approaches in tissue engineering, regenerative medicine, and nanomedicine offer the latest insights into the role immunomodulation in improving tolerance during tissue transplant in the treatment of orthopaedic, pancreatic, and hepatic diseases. "Immune Response to Implanted Materials and Devices" is intended for an audience of graduate students and professional researchers in both academia and industry interested in the development of smart strategies, which are able to exploit the self-healing properties of the body and achieve functional tissue restoration.

Emerging Trends in Immunomodulatory Nanomaterials Toward Cancer Therapy

Emerging Trends in Immunomodulatory Nanomaterials Toward Cancer Therapy
Author: Anubhab Mukherjee,Vijay Sagar Madamsetty,Sudip Mukherjee
Publsiher: Morgan & Claypool Publishers
Total Pages: 84
Release: 2021-04-06
ISBN 10: 1636391052
ISBN 13: 9781636391052
Language: EN, FR, DE, ES & NL

Emerging Trends in Immunomodulatory Nanomaterials Toward Cancer Therapy Book Review:

Recently, immunomodulatory nanomaterials have gained immense attention due to their involvement in the modulation of the body’s immune response to cancer therapy. This book highlights various immunomodulatory nanomaterials (including organic, polymer, inorganic, liposomes, viral, and protein nanoparticles) and their role in cancer therapy. Additionally, the mechanism of immunomodulation is reviewed in detail. Finally, the challenges of these therapies and their future outlook are discussed. We believe this book will be helpful to a broad community including students, researchers, educators, and industrialists.

Host Response to Biomaterials

Host Response to Biomaterials
Author: Stephen F Badylak
Publsiher: Academic Press
Total Pages: 460
Release: 2015-05-08
ISBN 10: 0128005009
ISBN 13: 9780128005002
Language: EN, FR, DE, ES & NL

Host Response to Biomaterials Book Review:

Host Response to Biomaterials: The Impact of Host Response on Biomaterial Selection explains the various categories of biomaterials and their significance for clinical applications, focusing on the host response to each biomaterial. It is one of the first books to connect immunology and biomaterials with regard to host response. The text also explores the role of the immune system in host response, and covers the regulatory environment for biomaterials, along with the benefits of synthetic versus natural biomaterials, and the transition from simple to complex biomaterial solutions. Fields covered include, but are not limited to, orthopaedic surgery, dentistry, general surgery, neurosurgery, urology, and regenerative medicine. Explains the various categories of biomaterials and their significance for clinical applications Contains a range of extensive coverage, including, but not limited to, orthopedic, surgery, dental, general surgery, neurosurgery, lower urinary tract, and regenerative medicine Includes regulations regarding combination devices

Peptides and Proteins as Biomaterials for Tissue Regeneration and Repair

Peptides and Proteins as Biomaterials for Tissue Regeneration and Repair
Author: Mario Barbosa,M Cristina L Martins
Publsiher: Woodhead Publishing
Total Pages: 390
Release: 2017-09-25
ISBN 10: 008100852X
ISBN 13: 9780081008522
Language: EN, FR, DE, ES & NL

Peptides and Proteins as Biomaterials for Tissue Regeneration and Repair Book Review:

Peptides and Proteins as Biomaterials for Tissue Regeneration and Repair highlights the various important considerations that go into biomaterial development, both in terms of fundamentals and applications. After covering a general introduction to protein and cell interactions with biomaterials, the book discusses proteins in biomaterials that mimic the extracellular matrix (ECM). The properties, fabrication and application of peptide biomaterials and protein-based biomaterials are discussed in addition to in vivo and in vitro studies. This book is a valuable resource for researchers, scientists and advanced students interested in biomaterials science, chemistry, molecular biology and nanotechnology. Presents an all-inclusive and authoritative coverage of the important role which protein and peptides play as biomaterials for tissue regeneration Explores protein and peptides from the fundamentals, to processing and applications Written by an international group of leading biomaterials researchers

Immunomodulatory Biomaterials to Mitigate Material induced Host Responses

Immunomodulatory Biomaterials to Mitigate Material induced Host Responses
Author: Yoon Kyung Kim
Publsiher: Unknown
Total Pages: 111
Release: 2013
ISBN 10: 9781303444975
ISBN 13: 1303444976
Language: EN, FR, DE, ES & NL

Immunomodulatory Biomaterials to Mitigate Material induced Host Responses Book Review:

The foreign body response to biomaterial implants has been a major challenge in translating many medical devices into the clinic. The presence of inflammatory cells around the implanted device prevents its functional interaction with the surrounding tissue, and although some inflammation may be desirable to mediate the healing process, a persistent inflammatory response will eventually lead to device failure. Significant efforts to reduce foreign body response have been largely focused on developing hydrophilic and anti-fouling coating materials, however, simply preventing protein adsorption and immune cell adhesion has only had moderate success at reducing inflammation in vivo. In this thesis, we describe a novel approach to mitigate the foreign body response, whereby materials are designed to mimic host tissue by displaying endogenously expressed immunomodulatory molecules that interact with specific inhibitory receptors expressed on immune cells. More specifically, biomaterial surfaces are coated with the recombinantly produced immunomodulatory molecule, CD200, which interacts with the inhibitory receptor CD200R on myeloid cells, preventing material-induced host response by suppressing activation of infiltrated myeloid cells. In Chapter One, a brief introduction and background information is presented, followed by a description of the production and purification of recombinant CD200 protein from both mammalian cells and bacterial cells in Chapter Two. In Chapter Three, we examine whether immobilization of CD200 onto polystyrene surfaces influences on suppressing the activation of macrophages. We found that CD200 indeed suppresses the release of inflammatory mediators secreted by macrophage cells in vitro, and elicited less inflammation in vivo when compared to uncoated materials after subcutaneous implantation. In Chapter Four, we examine whether CD200 influences tissue regeneration after spinal cord injury. CD200-embedded fibrin gel was implanted to spinal cord injured mice, and the effect of CD200 on inflammation and regenerative process was examined. Lastly, Chapter Five concludes the work performed in this Ph.D. study and presents future directions. This work suggests that coating of endogenously expressed immunomodulatory proteins can be used as a strategy to reduce inflammatory response to biomaterials and may potentially be generalized to implants throughout the body.

Bone Toxicology

Bone Toxicology
Author: Susan Y. Smith,Aurore Varela,Rana Samadfam
Publsiher: Springer
Total Pages: 474
Release: 2017-09-27
ISBN 10: 3319561928
ISBN 13: 9783319561929
Language: EN, FR, DE, ES & NL

Bone Toxicology Book Review:

The content of this book is intended to provide the toxicologist in drug development in the pharmaceutical and biotechnology industries with a broad understanding of bone and its interactions with other organ systems in safety assessments. The book is divided into three parts. The first part describes our current understanding of bone biology and its primary regulatory pathways. Additional chapters address regulatory and study design considerations for incorporating bone end points in toxicology studies, with special consideration being given to juvenile toxicology studies. This is intended to address recent regulatory requirements to evaluate skeletal development for drugs in development for pediatric populations. The second part of the book describes the principal techniques and methods used in bone research; understanding how these end-points are derived is fundamental to their appropriate application. These first two parts of the book provide the background and the means to develop the concepts in part three which describes bone and its interaction with other organ systems. The unique series of chapters in part three, contributed to by key leaders in their respective fields and in bone research, provides a comprehensive collective work. Although constantly evolving, the crosstalk and interaction of the skeleton with several organ systems is now recognized and well documented, such as for the reproductive system, muscle and kidney, while our understanding of the interaction with other organ systems, such as the immune system and CNS, is in its infancy. Recent work highlights the key role of the skeleton in the regulation of energy metabolism and the impact this has on research in metabolic diseases such as obesity and diabetes. The hope is that this book will enlighten many and encourage more to explore the impact of new compounds on the skeleton in the development of effective and safe drugs.

Biomaterials and Immune Response

Biomaterials and Immune Response
Author: Nihal Engin Vrana
Publsiher: CRC Press
Total Pages: 249
Release: 2018-07-20
ISBN 10: 1351377566
ISBN 13: 9781351377560
Language: EN, FR, DE, ES & NL

Biomaterials and Immune Response Book Review:

The interactions of the biomaterials with the host immune system is crucial for their functionality. This book aims to provide the reader with a better understanding of the role of the immune system in biomaterial applications. For this end, the book has dedicated chapters for i) explaining immune cells taking part in immune response to biomaterials/immune systems interface; ii) the effect of biomaterial shape, form and physicochemical properties on the response of immune system; iii) biofilm formation on implanted materials as a failure of immune system/biomaterial interactions; iv) tissue-specific effects of immune response and its consequences for tissue engineering and regenerative medicine; v) immune reaction in a clinical context (periodontology). In the field of biomaterials there are significant advances in using immunomodulation techniques to improve the success rates of implantable materials. For better understanding of such techniques it is required to have a full grasp of the biomaterial–immune system interactions. This would greatly enhance the understanding of why the human body reacts to implants in a certain way and how to improve the clinical outcomes by developing immune-instructive biomaterials. Provides keen insight into biomaterial–immune cell interactions Presents an explanation of state-of-the-art methodologies in immunomodulation Offers a concise and simple-to-understand treatment of biomaterial–immune cell interactions for materials scientists in a biology heavy topic Explores a comprehensive overview of biomaterial related complications Provides extensive references at the end of each chapter to enhance study for this very hot research area

Orthopedic Biomaterials

Orthopedic Biomaterials
Author: Bingyun Li,Thomas Webster
Publsiher: Springer
Total Pages: 496
Release: 2018-08-17
ISBN 10: 3319895427
ISBN 13: 9783319895420
Language: EN, FR, DE, ES & NL

Orthopedic Biomaterials Book Review:

This book covers the latest progress in the biology and manufacturing of orthopedic biomaterials, as well as key industry perspectives. Topics covered include the development of biomaterial-based medical products for orthopedic applications, anti-infection technologies for orthopedic implants, additive manufacturing of orthopedic implants, and more. This is an ideal book for graduate students, researchers and professionals working with orthopedic biomaterials and tissue engineering. This book also: Provides an industry perspective on technologies to prevent orthopedic implant related infection Thoroughly covers how to modulate innate inflammatory reactions in the application of orthopedic biomaterials Details the state-of-the-art research on 3D printed porous bone constructs

Biomaterials Science

Biomaterials Science
Author: William R Wagner,Shelly E. Sakiyama-Elbert,Guigen Zhang,Michael J. Yaszemski
Publsiher: Academic Press
Total Pages: 1616
Release: 2020-05-23
ISBN 10: 0128161388
ISBN 13: 9780128161388
Language: EN, FR, DE, ES & NL

Biomaterials Science Book Review:

The revised edition of the renowned and bestselling title is the most comprehensive single text on all aspects of biomaterials science from principles to applications. Biomaterials Science, fourth edition, provides a balanced, insightful approach to both the learning of the science and technology of biomaterials and acts as the key reference for practitioners who are involved in the applications of materials in medicine. This new edition incorporates key updates to reflect the latest relevant research in the field, particularly in the applications section, which includes the latest in topics such as nanotechnology, robotic implantation, and biomaterials utilized in cancer research detection and therapy. Other additions include regenerative engineering, 3D printing, personalized medicine and organs on a chip. Translation from the lab to commercial products is emphasized with new content dedicated to medical device development, global issues related to translation, and issues of quality assurance and reimbursement. In response to customer feedback, the new edition also features consolidation of redundant material to ensure clarity and focus. Biomaterials Science, 4th edition is an important update to the best-selling text, vital to the biomaterials’ community. The most comprehensive coverage of principles and applications of all classes of biomaterials Edited and contributed by the best-known figures in the biomaterials field today; fully endorsed and supported by the Society for Biomaterials Fully revised and updated to address issues of translation, nanotechnology, additive manufacturing, organs on chip, precision medicine and much more. Online chapter exercises available for most chapters

Polymeric Biomaterials for Healthcare Applications

Polymeric Biomaterials for Healthcare Applications
Author: Kokkarachedu Varaprasad
Publsiher: Woodhead Publishing
Total Pages: 450
Release: 2022-05-16
ISBN 10: 0323852343
ISBN 13: 9780323852340
Language: EN, FR, DE, ES & NL

Polymeric Biomaterials for Healthcare Applications Book Review:

Polymeric Biomaterials for Healthcare Applications details a broad range of polymeric biomaterials, methods of synthesis and preparation, and their various applications in healthcare and biomedicine. The book provides a fundamental overview of polymers and processing technologies to allow clinical scientists to explore the use of these polymers in alternative applications. A wide variety of healthcare applications are covered, including treatment for autoimmune diseases and bacterial infections, tissue engineering, gene delivery, wound dressing, and more. The book provides a core introductory text for clinical and materials scientists new to the area of polymeric biomaterials. This book will prove useful to academics and researchers in materials science, biomedical engineering, clinical science and pharmaceutical science. Covers a broad range of polymeric biomaterials, including chitosan, alginate, cellulose, collagen, synthetic conjugates, and more Details a wide variety of healthcare applications for polymeric biomaterials, such as orthopedic engineering, antibiotics, targeted drug delivery, and more Provides a detailed overview of polymer processing technologies and sterilization considerations

Engineering Materials for Stem Cell Regeneration

Engineering Materials for Stem Cell Regeneration
Author: Faheem A. Sheikh
Publsiher: Springer Nature
Total Pages: 706
Release: 2021-10-23
ISBN 10: 9811644209
ISBN 13: 9789811644207
Language: EN, FR, DE, ES & NL

Engineering Materials for Stem Cell Regeneration Book Review:

This book reviews the interface of stem cell biology and biomaterials for regenerative medicine. It presents the applications of biomaterials to support stem cell growth and regeneration. The book discusses the stem cell interactions’ with nanofiber, gradient biomaterial, polymer- and ceramic biomaterials, integrating top-down and bottom-up approaches, adhesive properties of stem cells on materials, cell-laden hydrogels, micro-and nanospheres, de-cellularization techniques, and use of porous scaffolds. Further, this book provides a basic introduction to the fabrication techniques for creating various biomaterials that can be used for stem cell differentiation. It also elucidates the properties of stem cells, their characteristic features, tissue culture technology, properties of pluripotency, osteogenesis, and biomaterial interaction with de-cellularized organs, cell lineage in vivo and in vitro, gene expression, embryonic development, and cell differentiation. Further, the book reviews the latest applications of bio-instructive scaffold for supporting stem cell differentiation and tissue regeneration. The book also presents stem cell for dental, alveolar bone and cardiac regeneration. Lastly, it introduces engineered stem cells for delivering small molecule therapeutics and their potential biomedical applications.

Biomimetic Medical Materials

Biomimetic Medical Materials
Author: Insup Noh
Publsiher: Springer
Total Pages: 399
Release: 2018-11-23
ISBN 10: 9811304459
ISBN 13: 9789811304453
Language: EN, FR, DE, ES & NL

Biomimetic Medical Materials Book Review:

This volume outlines the current status in the field of biomimetic medical materials and illustrates research into their applications in tissue engineering. The book is divided into six parts, focusing on nano biomaterials, stem cells, tissue engineering, 3D printing, immune responses and intellectual property. Each chapter has its own introduction and outlines current research trends in a variety of applications of biomimetic medical materials. The biomimetic medical materials that are covered include functional hydrogels, nanoparticles for drug delivery and medicine, the 3D bioprinting of biomaterials, sensor materials, stem cell interactions with biomaterials, immune responses to biomaterials, biodegradable hard scaffolds for tissue engineering, as well as other important topics, like intellectual property. Each chapter is written by a team of experts. This volume attempts to introduce the biomimetic properties of biomedical materials within the context of our current understanding of the nanotechnology of nanoparticles and fibres and the macroscopic aspects of 3D bioprinting.