Human Chorionic Gonadotropin hCG

Human Chorionic Gonadotropin  hCG
Author: Laurence A. Cole
Publsiher: Elsevier
Total Pages: 446
Release: 2014-12-11
ISBN 10: 0128008210
ISBN 13: 9780128008218
Language: EN, FR, DE, ES & NL

Human Chorionic Gonadotropin hCG Book Review:

Human chorionic gonadotropin (hCG) is produced during pregnancy by the embryo. It promotes progesterone production by corpus luteal cells. It also functions in pregnancy to promote angiogenesis in uterine vasculature, it immuno-blands the invading placental tissue so it is not rejected by the maternal uterine tissues, promotes the growth of the uterus in line with the growth of the fetus, promotes the differentiation of growing cytotrophoblast cells, promotes the quiescence of contractions in the uterine myometrium during the course of pregnancy, and also has function in growth and development of fetal organs. The first edition described the detailed biology, clinical chemistry, and clinical perspectives of hCG and associated molecules, and examines hCG, hyperglycosylated hCG and hCG free ß-subunit, 3 separate and independent molecules with totally sovereign physiological functions. The second edition will include coverage of the many new discoveries that have been made in the last five years: hCG analogues may be the actual driving signal of all human cancers. The editor estimates that 40% of the out of date material will be excluded and replaced with 40% of the exciting new findings. The book will also have a much clearer pregnancy and cancer focus. It provides comprehensive information on hCG from basic science to clinical medicine The second edition will include coverage of the many new discoveries that have been made in the last five years Updated material with new findings in the field

100 Years of Human Chorionic Gonadotropin

100 Years of Human Chorionic Gonadotropin
Author: Laurence A. Cole,Stephen A. Butler
Publsiher: Elsevier
Total Pages: 358
Release: 2020-02-07
ISBN 10: 0128216093
ISBN 13: 9780128216095
Language: EN, FR, DE, ES & NL

100 Years of Human Chorionic Gonadotropin Book Review:

100 years of Human Chorionic Gonadotropin: Reviews and New Perspectives is a collection of articles written by some of the world’s leading experts on the pregnancy hormone and cancer marker hCG. In 2019 it is difficult to ignore the effect that our understanding of hCG has had on the lives of millions of people worldwide. The hCG immunoassay, in one form or another, is now one of the most common medical tests conducted and is often the first indication that a mother-to-be is pregnant. Not only a marker of pregnancy, hCG is utilized in the diagnosis and monitoring in oncology and presents a potential target for novel cancer therapeutics. 100 years ago, in 1919, Hirose was demonstrating gonadotropic functions which resulted from a chorionic factor. Over the last century this factor has become defined as hCG and more recently explored as not one molecule but a group of molecules with variable structure and variable functions in both pregnancy and cancer. hCG is a multi-faceted molecule that has clinical and therapeutic implications but can be a challenging topic for researchers and physicians alike. This text covers the different structures and functions of hCG exploring the genes and evolution of the molecule, the different protein and glycosylation structures which can exist and their effect on structure, detection and quantification. 100 Years of hCG is not an attempt to recount the history of every publication on hCG, but rather a collection of reviews and new perspectives by "hCG-ologists", the term used by Hussa to describe biochemists working on HCG in the first book written on the topic over 30 years ago. Some of the authors have been around a while, some not so long, but others are just beginning their journey with a most beguiling molecule. Provides updated information on a complex and changing subject in five sections Reviews historical perspectives and developments over the last 100 years Includes novel insights into the structure, function and detection of hCG in pregnancy and cancer Includes chapters on the use of mass spectrometry to detect and quantify hCG as well as traditional immunoassays and over the counter pregnancy tests Describes the role of hCG in pregnancy, endometrial receptivity and embryo implantation and the use in fertility treatment Addresses the specific hyperglycosylated hCG test that can distinguish a normal term from a failing pregnancy and also screen for preeclampsia and gestational hypertension in pregnancy as well as its use as a marker and treatment target in cancer. Includes chapters on the development and use of hCG vaccines Includes a section on hCG and in subunits in cancer

Human Gonadotropins

Human Gonadotropins
Author: Laurence A. Cole,Stephen A. Butler
Publsiher: Elsevier
Total Pages: 268
Release: 2022-07-15
ISBN 10: 0128226323
ISBN 13: 9780128226322
Language: EN, FR, DE, ES & NL

Human Gonadotropins Book Review:

Human Gonadotropins is a must-have reference for basic science researchers looking to maximize their knowledge in this specific field of study. Luteinizing hormone, follicle-stimulating hormone, and human chorionic gonadotropin are essential for reproduction and outlined in detail in this work, covering topics ranging from antibodies and immunoassays, to commercial products and standards, genetics, and receptors and intermediaries for gonadotropins. Dr. Laurence Cole has been recognized for his outstanding research throughout his illustrious career. He has received awards from the Institute for Anticancer Research, Biannual Prize for best research; American Association for Clinical Chemistry, Most Outstanding Research Contributor to Clinical Chemistry Prize; Gynecology Oncology, Outstanding Speaker Award; and International Society for Study of Trophoblastic Disease, Gold Medal for most outstanding research. This detailed resource compiles all the recent research together into one volume, with one consistent voice. Covers the evolution, structure, synthesis, and functions of gonadotropins in meticulous detail Includes sections on Degradation, Antibodies and Immunoassays, Commercial Products and Standards, and Receptors and Intermediaries Details a section on Reproduction and Cancer, covering gestational trophoblastic diseases, ovarian cystic disorders, and hCG and cancer

Human Chorionic Gonadotropin hCG

Human Chorionic Gonadotropin  hCG
Author: Laurence A. Cole
Publsiher: Elsevier
Total Pages: 400
Release: 2010-09-21
ISBN 10: 012384908X
ISBN 13: 9780123849083
Language: EN, FR, DE, ES & NL

Human Chorionic Gonadotropin hCG Book Review:

Human chorionic gonadotropin (hCG) is produced during pregnancy by the embryo. It promotes progesterone production by corpus luteal cells. It also functions in pregnancy to promote angiogenesis in uterine vasculature, it immuno-blands the invading placental tissue so it is not rejected by the maternal uterine tissues, promotes the growth of the uterus in line with the growth of the fetus, promotes the differentiation of growing cytotrophoblast cells, promotes the quiescence of contractions in the uterine myometrium during the course of pregnancy, and also has function in growth and development of fetal organs. The book describes the detailed biology, clinical chemistry, and clinical perspectives of hCG and associated molecules, and examines hCG, hyperglycosylated hCG and hCG free ß-subunit, 3 separate and independent molecules with totally sovereign physiological functions. It provides comprehensive information on hCG from basic science to clinical medicine Written by specialists in the field

Bibliography of Gonadotropins for 1966

Bibliography of Gonadotropins for 1966
Author: Reproduction Information Center (National Institute of Child Health and Human Development),Martin L. Peller
Publsiher: Unknown
Total Pages: 192
Release: 1968
ISBN 10: 1928374650XXX
ISBN 13: UIUC:30112005987448
Language: EN, FR, DE, ES & NL

Bibliography of Gonadotropins for 1966 Book Review:

Structure and Function of the Gonadotropins

Structure and Function of the Gonadotropins
Author: Kenneth W. McKerns
Publsiher: Springer Science & Business Media
Total Pages: 630
Release: 2012-12-06
ISBN 10: 1468434144
ISBN 13: 9781468434149
Language: EN, FR, DE, ES & NL

Structure and Function of the Gonadotropins Book Review:

In September of 1977 scientists from many countries met at the Asticou Inn in Maine to present and discuss papers written especially for this monograph. The presentations were informal and directed to the special interests of the audience in order to generate discussions. The authors, many of whom are pioneers and leaders in their field, then had the oppor tunity to revise their contributions, which were brought together with the edited discussions to form this volume. The basic research studies presented here are important because of the essential role of gonadotropins in regulating the ovary and testis. This monograph will therefore be of interest to those concerned with fertility regulation, population control, possible new methods for contraception, and to those concerned with reproduction in domestic animals. Re searchers in other fields may find this monograph useful, as it has been de termined that gonadotropins are secreted by many tumors and are im plicated in many cancers. Human choriogonadotropin also seems to be found in most, if not all, cells of the human body. The significance of this, however, is unknown.

GnRH GnRH Analogs Gonadotropins and Gonadal Peptides

GnRH  GnRH Analogs  Gonadotropins and Gonadal Peptides
Author: P. Bouchard,A. Caraty
Publsiher: CRC Press
Total Pages: 620
Release: 1993-11-15
ISBN 10: 9780203092057
ISBN 13: 0203092058
Language: EN, FR, DE, ES & NL

GnRH GnRH Analogs Gonadotropins and Gonadal Peptides Book Review:

A comprehensive review, providing an assessment of the current status of knowledge on GnRH. The topics covered include - gonadotropin releasing hormone, gonadotropin releasing hormone agonists, gonadotropin releasing hormone antagonists and gonadotropin and gonadal peptides.

Population Sciences

Population Sciences
Author: Anonim
Publsiher: Unknown
Total Pages: 135
Release: 1973
ISBN 10: 1928374650XXX
ISBN 13: MSU:31293201519042
Language: EN, FR, DE, ES & NL

Population Sciences Book Review:

Chorionic Gonadotropin

Chorionic Gonadotropin
Author: Sheldon J. Segal
Publsiher: Springer Science & Business Media
Total Pages: 508
Release: 2012-12-06
ISBN 10: 1468410628
ISBN 13: 9781468410624
Language: EN, FR, DE, ES & NL

Chorionic Gonadotropin Book Review:

This volume is devoted to the chemistry, immunology, molecular biology, and physiology of the human chorionic gonadotropin, heG. For this glycoprotein molecule the course from discovery to chemical deciphering covered about fifty years. It was in 1928 that Ascheim and Zondek reported that urine from pregnant women contains something that stimulates the ovaries of mice or rats. This provided the basis for the famous A-Z test for pregnancy and for the "rabbit test" modification introduced by Friedman. As researchers sought to find more sensitive responses to heG, they used a wide variety of species including the South African aquatic toad, Xenopus Zaevis, the terrestrial toad of South America, Bufo arinarus, and the African weaver finch, EupZeetes afra. The weaver finch feather reaction was particularly noteworthy, for it disclosed a non-gonadal response to heG/LH. In retrospect, this may have been an important evolutionary clue to the realization that the designation of the hormone as a "gonadotropin" may have been only partially descriptive of the molecule's physiological function--a concept that is gaining attention, as the papers in this 1980 volume divulge.

Endocrinology of the Testis and Male Reproduction

Endocrinology of the Testis and Male Reproduction
Author: Manuela Simoni,Ilpo T. Huhtaniemi
Publsiher: Springer
Total Pages: 1364
Release: 2017-09-18
ISBN 10: 9783319444406
ISBN 13: 3319444409
Language: EN, FR, DE, ES & NL

Endocrinology of the Testis and Male Reproduction Book Review:

This book provides a comprehensive overview of endocrinology of the male reproductive system, explaining how it works and how, sometimes, it fails to work. World-class specialists present state of the art knowledge on all aspects, including anatomy, physiology, molecular biology, genetics, pathophysiology, clinical manifestations of testicular diseases, endocrine aspects of andrological and sexual diseases, and therapy. Extensive consideration is given to sexual development, testicular function, the clinical approach to disorders of male reproduction, male hypogonadism, sexual dysfunction, and male infertility. In addition, sociodemographic, psychological, and ethical aspects of male reproductive disorders are discussed. The book is intended as a major reference for endocrinologists, andrologists, and sexologists, as well as basic and clinical scientists. It is published as part of the SpringerReference program, which delivers access to living editions constantly updated through a dynamic peer-review publishing process.

Gonadotropins From Bench Side to Bedside

Gonadotropins  From Bench Side to Bedside
Author: Rajendra T. Kumar
Publsiher: Academic Press
Total Pages: 230
Release: 2016-09-30
ISBN 10: 0128012668
ISBN 13: 9780128012666
Language: EN, FR, DE, ES & NL

Gonadotropins From Bench Side to Bedside Book Review:

Gonadotropins: From Bench Side to Bedside, the latest volume in the Progress in Molecular Biology and Translational Science series, focuses on all aspects of gonadotropins, from research to treatment. Contains contributions from leading authorities on the topic Publishes cutting-edge reviews in molecular biology Informs and updates on all the latest developments available regarding the research of gonadotropins

100 Years of Human Chorionic Gonadotropin

100 Years of Human Chorionic Gonadotropin
Author: Laurence A. Cole,Stephen A. Butler
Publsiher: Unknown
Total Pages: 358
Release: 2020-02-17
ISBN 10: 0128200502
ISBN 13: 9780128200506
Language: EN, FR, DE, ES & NL

100 Years of Human Chorionic Gonadotropin Book Review:

100 years of Human Chorionic Gonadotropin: Reviews and New Perspectives is a collection of articles written by some of the world's leading experts on the pregnancy hormone and cancer marker hCG. In 2019 it is difficult to ignore the effect that our understanding of hCG has had on the lives of millions of people worldwide. The hCG immunoassay, in one form or another, is now one of the most common medical tests conducted and is often the first indication that a mother-to-be is pregnant. Not only a marker of pregnancy, hCG is utilized in the diagnosis and monitoring in oncology and presents a potential target for novel cancer therapeutics. 100 years ago, in 1919, Hirose was demonstrating gonadotropic functions which resulted from a chorionic factor. Over the last century this factor has become defined as hCG and more recently explored as not one molecule but a group of molecules with variable structure and variable functions in both pregnancy and cancer. hCG is a multi-faceted molecule that has clinical and therapeutic implications but can be a challenging topic for researchers and physicians alike. This text covers the different structures and functions of hCG exploring the genes and evolution of the molecule, the different protein and glycosylation structures which can exist and their effect on structure, detection and quantification. 100 Years of hCG is not an attempt to recount the history of every publication on hCG, but rather a collection of reviews and new perspectives by "hCG-ologists", the term used by Hussa to describe biochemists working on HCG in the first book written on the topic over 30 years ago. Some of the authors have been around a while, some not so long, but others are just beginning their journey with a most beguiling molecule. Provides updated information on a complex and changing subject in five sections Reviews historical perspectives and developments over the last 100 years Includes novel insights into the structure, function and detection of hCG in pregnancy and cancer Includes chapters on the use of mass spectrometry to detect and quantify hCG as well as traditional immunoassays and over the counter pregnancy tests Describes the role of hCG in pregnancy, endometrial receptivity and embryo implantation and the use in fertility treatment Addresses the specific hyperglycosylated hCG test that can distinguish a normal term from a failing pregnancy and also screen for preeclampsia and gestational hypertension in pregnancy as well as its use as a marker and treatment target in cancer. Includes chapters on the development and use of hCG vaccines Includes a section on hCG and in subunits in cancer

Diagnostic Electron Microscopy

Diagnostic Electron Microscopy
Author: Anonim
Publsiher: Unknown
Total Pages: 560
Release: 1980
ISBN 10: 1928374650XXX
ISBN 13: UCLA:31158005520407
Language: EN, FR, DE, ES & NL

Diagnostic Electron Microscopy Book Review:

Research Grants Index

Research Grants Index
Author: National Institutes of Health (U.S.). Division of Research Grants
Publsiher: Unknown
Total Pages: 1074
Release: 1969
ISBN 10: 1928374650XXX
ISBN 13: IND:30000090423892
Language: EN, FR, DE, ES & NL

Research Grants Index Book Review:

Psychological Perspectives On Women s Health

Psychological Perspectives On Women s Health
Author: Vincent J. Adesso
Publsiher: Taylor & Francis
Total Pages: 360
Release: 2013-08-21
ISBN 10: 1135059136
ISBN 13: 9781135059132
Language: EN, FR, DE, ES & NL

Psychological Perspectives On Women s Health Book Review:

Significant scientific advances have been made in understanding psychological aspects of women's health, and knowledge gained will be of relevance not only to women's health but to the promotion of health and illness prevention and treatment for all individuals. The current cutting-edge research detailed in this volume is intended to stimulate new thinking and research in women's health from biopsychosocial perspectives. Drawing on research from internationally respected experts, topics covered include ageing, stress, heart disease, cancer, drugs, weight regulation and body image, pain, menstruation, sexuality and infertility, and AIDS.

Gonadotropin Releasing Hormone Receptor Signaling and Functions

Gonadotropin Releasing Hormone Receptor Signaling and Functions
Author: Ivana Bjelobaba,Stanko S. Stojilkovic,Zvi Naor
Publsiher: Frontiers Media SA
Total Pages: 135
Release: 2018-05-10
ISBN 10: 2889454797
ISBN 13: 9782889454792
Language: EN, FR, DE, ES & NL

Gonadotropin Releasing Hormone Receptor Signaling and Functions Book Review:

This eBook provides a comprehensive overview of our current knowledge on Gonadotropin-releasing hormone receptor evolution, structure, signaling and functions. Apart from review articles, it comprises exciting new research, as well as hypotheses and perspectives, all of which are valuable in guiding our further research in this field.

Research Awards Index

Research Awards Index
Author: Anonim
Publsiher: Unknown
Total Pages: 135
Release: 1978
ISBN 10: 1928374650XXX
ISBN 13: MINN:30000008789962
Language: EN, FR, DE, ES & NL

Research Awards Index Book Review:

Journal of Reproductive Medicine

Journal of Reproductive Medicine
Author: Anonim
Publsiher: Unknown
Total Pages: 135
Release: 1996
ISBN 10: 1928374650XXX
ISBN 13: UCLA:L0075677757
Language: EN, FR, DE, ES & NL

Journal of Reproductive Medicine Book Review:

Clinical Application of Human Gonadotropins

Clinical Application of Human Gonadotropins
Author: Gerhard Bettendorf,Vaclav Insler
Publsiher: Unknown
Total Pages: 180
Release: 1970
ISBN 10: 1928374650XXX
ISBN 13: UOM:39015072267910
Language: EN, FR, DE, ES & NL

Clinical Application of Human Gonadotropins Book Review:

Gonadotropins and Gonadal Function

Gonadotropins and Gonadal Function
Author: N Moudgal
Publsiher: Elsevier
Total Pages: 588
Release: 2012-12-02
ISBN 10: 0323145124
ISBN 13: 9780323145121
Language: EN, FR, DE, ES & NL

Gonadotropins and Gonadal Function Book Review:

Gonadotropins and Gonadal Function presents the proceedings of the International Symposium on the Advances in Chemistry, Biology and Immunology of Gonadotropins, held at the Indian Institute of Science, Bangalore, India in October 1973. The book reviews the chemistry, physiology and biochemical mechanism of action of gonadotropins. The compendium is divided into four sections. Section I discusses the chemistry of gonadotropins. Section II covers the biology and immunology of gonadotropins. The third section tackles the biochemistry of gonadotropins. The final section presents gonadotropins in clinical medicine. Endocrinologists, physicians, biochemists, and medical researchers will find the book highly interesting.