Heart Development and Regeneration

Heart Development and Regeneration
Author: Nadia Rosenthal,Richard P. Harvey
Publsiher: Academic Press
Total Pages: 1136
Release: 2010-05-28
ISBN 10: 0123813336
ISBN 13: 9780123813336
Language: EN, FR, DE, ES & NL

Heart Development and Regeneration Book Review:

The development of the cardiovascular system is a rapidly advancing area in biomedical research, now coupled with the burgeoning field of cardiac regenerative medicine. A lucid understanding of these fields is paramount to reducing human cardiovascular diseases of both fetal and adult origin. Significant progress can now be made through a comprehensive investigation of embryonic development and its genetic control circuitry. Heart Development and Regeneration, written by experts in the field, provides essential information on topics ranging from the evolution and lineage origins of the developing cardiovascular system to cardiac regenerative medicine. A reference for clinicians, medical researchers, students, and teachers, this publication offers broad coverage of the most recent advances. Volume One discusses heart evolution, contributing cell lineages; model systems; cardiac growth; morphology and asymmetry; heart patterning; epicardial, vascular, and lymphatic development; and congenital heart diseases. Volume Two includes chapters on transcription factors and transcriptional control circuits in cardiac development and disease; epigenetic modifiers including microRNAs, genome-wide mutagenesis, imaging, and proteomics approaches; and the theory and practice of stem cells and cardiac regeneration. Authored by world experts in heart development and disease New research on epigenetic modifiers in cardiac development Comprehensive coverage of stem cells and prospects for cardiac regeneration Up-to-date research on transcriptional and proteomic circuits in cardiac disease Full-color, detailed illustrations

Cardiac Regeneration

Cardiac Regeneration
Author: Masaki Ieda,Wolfram-Hubertus Zimmermann
Publsiher: Springer
Total Pages: 274
Release: 2017-10-27
ISBN 10: 3319561065
ISBN 13: 9783319561066
Language: EN, FR, DE, ES & NL

Cardiac Regeneration Book Review:

This Volume of the series Cardiac and Vascular Biology offers a comprehensive and exciting, state-of-the-art work on the current options and potentials of cardiac regeneration and repair. Several techniques and approaches have been developed for heart failure repair: direct injection of cells, programming of scar tissue into functional myocardium, and tissue-engineered heart muscle support. The book introduces the rationale for these different approaches in cell-based heart regeneration and discusses the most important considerations for clinical translation. Expert authors discuss when, why, and how heart muscle can be salvaged. The book represents a valuable resource for stem cell researchers, cardiologists, bioengineers, and biomedical scientists studying cardiac function and regeneration.

Heart Development and Regeneration

Heart Development and Regeneration
Author: Nadia Rosenthal,Richard P. Harvey
Publsiher: Academic Press
Total Pages: 1136
Release: 2010
ISBN 10: 0123813328
ISBN 13: 9780123813329
Language: EN, FR, DE, ES & NL

Heart Development and Regeneration Book Review:

Annotation The development of the cardiovascular system is a rapidly advancing area in biomedical research, now coupled with the burgeoning field of cardiac regenerative medicine. A lucid understanding of these fields is paramount to reducing human cardiovascular diseases of both fetal and adult origin. Significant progress can now be made through a comprehensive investigation of embryonic development and its genetic control circuitry. Heart Development and Regeneration, written by experts in the field, provides essential information on topics ranging from the evolution and lineage origins of the developing cardiovascular system to cardiac regenerative medicine. A reference for clinicians, medical researchers, students, and teachers, this publication offers broad coverage of the most recent advances. Volume One discusses heart evolution, contributing cell lineages; model systems; cardiac growth; morphology and asymmetry; heart patterning; epicardial, vascular, and lymphatic development; and congenital heart diseases. Volume Two includes chapters on transcription factors and transcriptional control circuits in cardiac development and disease; epigenetic modifiers including microRNAs, genome-wide mutagenesis, imaging, and proteomics approaches; and the theory and practice of stem cells and cardiac regeneration. Authored by world experts in heart development and disease New research on epigenetic modifiers in cardiac development Comprehensive coverage of stem cells and prospects for cardiac regeneration Up-to-date research on transcriptional and proteomic circuits in cardiac disease Full-color, detailed illustrations.

Heart Development and Regeneration

Heart Development and Regeneration
Author: Felix B. Engel
Publsiher: Unknown
Total Pages: 135
Release: 2012
ISBN 10: 1928374650XXX
ISBN 13: OCLC:974005969
Language: EN, FR, DE, ES & NL

Heart Development and Regeneration Book Review:

Cardiac Regeneration and Repair Pathology and Therapies

Cardiac Regeneration and Repair  Pathology and Therapies
Author: Ren-Ke Li,Richard D. Weisel
Publsiher: Woodhead Publishing
Total Pages: 448
Release: 2017-11-13
ISBN 10: 9780081015766
ISBN 13: 0081015763
Language: EN, FR, DE, ES & NL

Cardiac Regeneration and Repair Pathology and Therapies Book Review:

"Cardiac Regeneration and Repair, Volume One" reviews the pathology of cardiac injury and the latest advances in cell therapy. Chapters in part one explore the pathogenesis of congestive heart failure, the mechanisms responsible for adverse cardiac matrix remodeling, and potential interventions to restore ventricular function. Part two highlights new approaches to cell therapy for cardiac regeneration, and includes chapters covering alternative routes of cell delivery, monitoring cell engraftment, and the feasibility of using allogeneic stem cells to restore cardiac function. Chapters in part three move on to highlight novel stem cells for cardiac repair, including human embryonic stem cells and human pluripotent stem cells, and detail their current status and future potential for cardiac therapy. Finally, part four explores gene therapy, and includes ultrasound-targeted or direct gene delivery as well as cell-based gene therapy for cardiac regeneration. "Cardiac Regeneration and Repair, Volume One" is complemented by a second volume covering biomaterials and tissue engineering. Together, the two volumes of "Cardiac Regeneration and Repair" provide a comprehensive resource for clinicians, scientists, or academicians fascinated with cardiac regeneration, including those interested in cell therapy, tissue engineering, or biomaterials. Explores the pathogenesis of congestive heart failure, the mechanisms responsible for adverse cardiac matrix remodeling, and potential interventions to restore ventricular functionHighlights new approaches to cell therapy for cardiac regeneration and includes chapters covering alternative routes of cell delivery, monitoring cell engraftment, and the feasibility of using allogeneic stem cells to restore cardiac functionExplores gene therapy and includes ultrasound-targeted or direct gene delivery as well as cell-based gene therapy for cardiac regeneration

Biomaterials for Cardiac Regeneration

Biomaterials for Cardiac Regeneration
Author: Erik J. Suuronen,Marc Ruel
Publsiher: Springer
Total Pages: 323
Release: 2014-11-12
ISBN 10: 3319109723
ISBN 13: 9783319109725
Language: EN, FR, DE, ES & NL

Biomaterials for Cardiac Regeneration Book Review:

This book offers readers a comprehensive biomaterials-based approach to achieving clinically successful, functionally integrated vasculogenesis and myogenesis in the heart. Coverage is multidisciplinary, including the role of extracellular matrices in cardiac development, whole-heart tissue engineering, imaging the mechanisms and effects of biomaterial-based cardiac regeneration, and autologous bioengineered heart valves. Bringing current knowledge together into a single volume, this book provides a compendium to students and new researchers in the field and constitutes a platform to allow for future developments and collaborative approaches in biomaterials-based regenerative medicine, even beyond cardiac applications.

Heart Development

Heart Development
Author: Benoit G. Bruneau
Publsiher: Academic Press
Total Pages: 391
Release: 2012
ISBN 10: 0123877865
ISBN 13: 9780123877864
Language: EN, FR, DE, ES & NL

Heart Development Book Review:

The developing heart is the first functional organ, and its proper formation and function is essential for life. This volume compiles the exciting new advances that have been made in understanding the regulation of heart development, the genes and pathways involved, and the impact these have in heart disease. A stellar collection of scientists tackles an important facet of heart development, providing a comprehensive set of reviews. Cutting-edge science Authority of contributors Exciting field of research

Heart Development

Heart Development
Author: Richard A. Harvey,Richard P. Harvey,Nadia Rosenthal,Richard A Harvey, PhD
Publsiher: Gulf Professional Publishing
Total Pages: 530
Release: 1999
ISBN 10: 9780123298607
ISBN 13: 0123298601
Language: EN, FR, DE, ES & NL

Heart Development Book Review:

This book examines recent studies revealing that the same genes are responsible for development of parallel features between species, and that the heart develops similarly across all species. It includes research being conducted concerning cardiac development, tissue interaction, and organ formation. The text attempts to provide a greater understanding of the underlying causes of heart failure, heart muscle diseases, congenital malformations, and other heart diseases and defects. Key Features * Each chapter has been solicited from a recognized leader in the field, and covers a topic of active research in cardiovascular biology * Chapters incorporate a review of classical findings with comprehensive coverage of the latest advances * Abundant color plates in a consistent and professional artistic style provide clear and attractive illustrations of central concepts * Color slides of illustrations for seminars or teaching purposes are available with each volume

The Hippo Pathway s Role in Zebrafish Cardiac Development and Regeneration

The Hippo Pathway s Role in Zebrafish Cardiac Development and Regeneration
Author: Michael Andrew Flinn
Publsiher: Unknown
Total Pages: 141
Release: 2018
ISBN 10: 9781085584937
ISBN 13: 1085584933
Language: EN, FR, DE, ES & NL

The Hippo Pathway s Role in Zebrafish Cardiac Development and Regeneration Book Review:

Cardiac Regeneration and Repair

Cardiac Regeneration and Repair
Author: Ren-Ke Li,Richard D. Weisel
Publsiher: Elsevier
Total Pages: 486
Release: 2014-02-17
ISBN 10: 0857096710
ISBN 13: 9780857096715
Language: EN, FR, DE, ES & NL

Cardiac Regeneration and Repair Book Review:

Cardiac Regeneration and Repair, Volume Two reviews the use of biomaterials, alone or combined with cell therapy, in providing tissue-engineered constructs to repair the injured heart and prevent or reverse heart failure. Part one explores the variety of biomaterials available for cardiac repair, including nanomaterials and hydrogels. Further chapters explore the use of biomaterials to enhance stem cell therapy for restoring ventricular function and generating stem cell-modified intravascular stents. Part two focuses on tissue engineering for cardiac repair, including chapters on decellularized biologic scaffolds, synthetic scaffolds, cell sheet engineering, maturation of functional cardiac tissue patches, vascularized engineered tissues for in vivo and in vitro applications, and clinical considerations for cardiac tissue engineering. Finally, part three explores vascular remodeling, including chapters highlighting aortic extracellular matrix remodeling, cell-biomaterial interactions for blood vessel formation, and stem cells for tissue-engineered blood vessels. Cardiac Regeneration and Repair, Volume Two is complemented by an initial volume covering pathology and therapies. Together, the two volumes of Cardiac Regeneration and Repair provide a comprehensive resource for clinicians, scientists, or academicians fascinated with cardiac regeneration, including those interested in cell therapy, tissue engineering, or biomaterials. Surveys the variety of biomaterials available for cardiac repair, including nanomaterials and hydrogels. Focuses on tissue engineering for cardiac repair including clinical considerations for cardiac tissue engineering Explores vascular remodeling, highlighting aortic extracellular matrix remodeling, cell-biomaterial interactions for blood vessel formation, and stem cells for tissue-engineered blood vessels

Heart Development

Heart Development
Author: Anonim
Publsiher: Academic Press
Total Pages: 408
Release: 2012-05-10
ISBN 10: 0123877903
ISBN 13: 9780123877901
Language: EN, FR, DE, ES & NL

Heart Development Book Review:

The developing heart is the first functional organ, and its proper formation and function is essential for life. This volume compiles the exciting new advances that have been made in understanding the regulation of heart development, the genes and pathways involved, and the impact these have in heart disease. A stellar collection of scientists tackles an important facet of heart development, providing a comprehensive set of reviews. Cutting-edge science Authority of contributors Exciting field of research

RNA Regulons During Heart Development and Regeneration

RNA Regulons During Heart Development and Regeneration
Author: Wenjie Yao
Publsiher: Unknown
Total Pages: 176
Release: 2020
ISBN 10: 1928374650XXX
ISBN 13: OCLC:1244115878
Language: EN, FR, DE, ES & NL

RNA Regulons During Heart Development and Regeneration Book Review:

Cardiac Regeneration using Stem Cells

Cardiac Regeneration using Stem Cells
Author: Keiichi Fukuda,Shinsuke Yuasa
Publsiher: CRC Press
Total Pages: 342
Release: 2013-04-10
ISBN 10: 1466578408
ISBN 13: 9781466578401
Language: EN, FR, DE, ES & NL

Cardiac Regeneration using Stem Cells Book Review:

To achieve cardiac regeneration using pluripotent stem (iPS) cells, researchers must understand iPS cell generation methods, cardiomyocyte differentiation protocols, cardiomyocyte characterization methods, and tissue engineering. This book presents the current status and future possibilities in cardiac regeneration using iPS cells. Written by top researchers who present new data in these fields, this book reviews cardiac cell therapy for ischemic heart disease and explores in vitro generation of efficacious platelets from iPS cells. It also discusses modeling arrhythmogenic heart disease with patient-specific induced pluripotent stem cells.

Anatomy and Physiology

Anatomy and Physiology
Author: J. Gordon Betts,Peter DeSaix,Jody E. Johnson,Oksana Korol,Dean H. Kruse,Brandon Poe,James A. Wise,Mark Womble,Kelly A. Young
Publsiher: Unknown
Total Pages: 135
Release: 2013-04-25
ISBN 10: 9781947172807
ISBN 13: 1947172808
Language: EN, FR, DE, ES & NL

Anatomy and Physiology Book Review:

Manipulating the Mouse Embryo

Manipulating the Mouse Embryo
Author: Andras Nagy,Marina Gertsenstein,Kristina Vintersten,Richard Behringer
Publsiher: Cold Spring Harbor, N.Y. : Cold Spring Harbor Laboratory Press
Total Pages: 764
Release: 2003
ISBN 10: 1928374650XXX
ISBN 13: UOM:39015056178109
Language: EN, FR, DE, ES & NL

Manipulating the Mouse Embryo Book Review:

Provides information and guidelines for developing a mouse colony and conducting experiments, including proper protocols, step-by-step procedures, and analysis strategies.

Cardiovascular Regenerative Medicine

Cardiovascular Regenerative Medicine
Author: Vahid Serpooshan,Sean M. Wu
Publsiher: Springer
Total Pages: 233
Release: 2019-06-29
ISBN 10: 3030200477
ISBN 13: 9783030200473
Language: EN, FR, DE, ES & NL

Cardiovascular Regenerative Medicine Book Review:

This book is a comprehensive and up-to-date resource on the use of regenerative medicine for the treatment of cardiovascular disease. It provides a much-needed review of the rapid development and evolution of bio-fabrication techniques to engineer cardiovascular tissues as well as their use in clinical settings. The book incorporates recent advances in the biology, biomaterial design, and manufacturing of bioengineered cardiovascular tissue with their clinical applications to bridge the basic sciences to current and future cardiovascular treatment. The book begins with an examination of state-of-the-art cellular, biomaterial, and macromolecular technologies for the repair and regeneration of diseased heart tissue. It discusses advances in nanotechnology and bioengineering of cardiac microtissues using acoustic assembly. Subsequent chapters explore the clinical applications and translational potential of current technologies such as cardiac patch-based treatments, cell-based regenerative therapies, and injectable hydrogels. The book examines how these methodologies are used to treat a variety of cardiovascular diseases including myocardial infarction, congenital heart disease, and ischemic heart injuries. Finally, the volume concludes with a summary of the most prominent challenges and perspectives on the field of cardiovascular tissue engineering and clinical cardiovascular regenerative medicine. Cardiovascular Regenerative Medicine is an essential resource for physicians, residents, fellows, and medical students in cardiology and cardiovascular regeneration as well as clinical and basic researchers in bioengineering, nanomaterial and technology, and cardiovascular biology.

Cardiomyocyte Regeneration and the Potential Role of Neonatal Systemic Factors

Cardiomyocyte Regeneration and the Potential Role of Neonatal Systemic Factors
Author: Ngoc Nguyen
Publsiher: Unknown
Total Pages: 119
Release: 2021
ISBN 10: 1928374650XXX
ISBN 13: OCLC:1245254368
Language: EN, FR, DE, ES & NL

Cardiomyocyte Regeneration and the Potential Role of Neonatal Systemic Factors Book Review:

There are tremendous health and financial burdens attributed to cardiovascular disease. The most common type, known as ischemic heart disease, is due to plaque buildup within the coronary arteries that supply the myocardium with oxygen and nutrients. Reduction or blockage of blood flow can lead to irreversible loss of cardiomyocytes, the main building blocks of the heart, with estimates placing that loss to upward of a billion cells. Despite medical therapy, the majority of patients eventually progress to heart failure, in which the main challenge for the development of therapeutic strategies is the limited regenerative ability of the adult mammalian heart. Our dissertation takes a multi-faceted approach in understanding cardiac regeneration and exploring whether neonatal systemic factors could be the gateway to a new therapy for ischemic heart disease. We report the development of a multi-colored mouse reporter system that enables deeper understanding of the cellular mechanisms driving early cardiac tissue formation. We apply a bioengineering approach to develop biodegradable and biocompatible nanoparticles as a new tool for clonal expansion analysis of cardiac cells. And lastly, we examined the proteomic profile of neonatal plasma in order to identify potential "pro-youthful" factors that may prevent irreversible myocardial damage. We hope that our body of work pushes forward the field of cardiac regeneration and sets the stage for the development of therapeutic interventions to prevent the progression to heart failure after an acute myocardial infarction.

Modern Mechanobiology

Modern Mechanobiology
Author: Juhyun Lee,Sharon Gerecht,Hanjoong Jo,Tzung Hsiai
Publsiher: CRC Press
Total Pages: 262
Release: 2021-02-25
ISBN 10: 1000021262
ISBN 13: 9781000021264
Language: EN, FR, DE, ES & NL

Modern Mechanobiology Book Review:

Modern mechanobiology converges both engineering and medicine to address personalized medicine. This book is built on the previously well-received edition, Hemodynamics and Mechanobiology of Endothelium. The central theme is "omic" approaches to mechanosignal transduction underlying tissue development, injury, and repair. A cadre of investigators has contributed to the chapters, enriching the interface between mechanobiology and precision medicine for personalized diagnosis and intervention. The book begins with the fundamental basis of vascular disease in response to hemodynamic shear stress and then details cardiovascular development and regeneration, valvular and cardiac morphogenesis, mechanosensitive microRNA and histone unfolding, computational fluid dynamics, and light-sheet imaging. This edition represents a paradigm shift from traditional biomechanics and signal transduction to transgenic models, including novel zebrafish and chick embryos, and targets a wider readership from academia to industry and government agencies in the field of mechanobiology.

Principles of Regenerative Medicine

Principles of Regenerative Medicine
Author: Anthony Atala,Robert Lanza,James A. Thomson,Robert Nerem
Publsiher: Academic Press
Total Pages: 1202
Release: 2010-12-16
ISBN 10: 9780123814234
ISBN 13: 0123814235
Language: EN, FR, DE, ES & NL

Principles of Regenerative Medicine Book Review:

Virtually any disease that results from malfunctioning, damaged, or failing tissues may be potentially cured through regenerative medicine therapies, by either regenerating the damaged tissues in vivo, or by growing the tissues and organs in vitro and implanting them into the patient. Principles of Regenerative Medicine discusses the latest advances in technology and medicine for replacing tissues and organs damaged by disease and of developing therapies for previously untreatable conditions, such as diabetes, heart disease, liver disease, and renal failure. Key for all researchers and instituions in Stem Cell Biology, Bioengineering, and Developmental Biology The first of its kind to offer an advanced understanding of the latest technologies in regenerative medicine New discoveries from leading researchers on restoration of diseased tissues and organs

Epigenetics and Regeneration

Epigenetics and Regeneration
Author: Anonim
Publsiher: Academic Press
Total Pages: 541
Release: 2019-05-24
ISBN 10: 0128148802
ISBN 13: 9780128148808
Language: EN, FR, DE, ES & NL

Epigenetics and Regeneration Book Review:

Epigenetics and Regeneration compiles the first foundational reference on epigenetic mechanisms governing tissue development, repair, homeostasis, and regeneration, as well as pathways to employ these mechanisms in clinical practice and translational science. In this book, life science researchers, clinicians, and students will discover an interdisciplinary resource bringing together common themes in the field, background overviews, research methods, recent advances, and opportunities for drug discovery. Throughout this volume, special attention is paid to pre-clinical and first clinical studies aimed at increasing the regenerative potential of damaged tissues by epigenetic drugs, as well as innovative, discipline spanning strategies to enhance cell reprogramming. As an all-inclusive, evidence-based volume, Epigenetics and Regeneration will stimulate discussion and boost new research in this fascinating and impactful area of translational epigenetics. Provides a foundational overview of epigenetics in regenerative medicine Examines epigenetic components of tissue regeneration for a variety of organ systems and tissue types, as well as current attempts to employ these mechanisms in clinical practice Offers researchers, students, clinicians, and pharmacologists the tools they need to enhance tissue development, repair, homeostasis, and regeneration and explore new epigenetic therapeutic pathways Features chapter contributions from leading international researchers and clinicians in the fields of epigenetics and regenerative medicine