Global Health Complications of Obesity

Global Health Complications of Obesity
Author: Jahangir Moini,Raheleh Ahangari,Carrie Miller,Mohtashem Samsam
Publsiher: Elsevier
Total Pages: 480
Release: 2020-04-01
ISBN 10: 0128197528
ISBN 13: 9780128197523
Language: EN, FR, DE, ES & NL

Global Health Complications of Obesity Book Review:

Global Health Complications of Obesity presents a valuable resource for research scientists and clinicians by covering the burden of obesity and related diseases and serving as a starting point for in-depth discussions in academic settings and for obesity-treatment specialists. Obesity is associated with a statistically higher risk of heart disease, hypertension, insulin resistance, type 2 diabetes and many other diseases. This succinct resource focuses on the current data, research and management of obesity. It is essential reading for healthcare professionals, endocrinologists, nutritionists, public health students and medical students. Presents clinical cases, key terms and targeted references Addresses diseases including diabetes, cancer, hypertension, osteoarthritis, fatty liver disease, infertility, renal failure and depression Provides a link to new knowledge that is ideal for both researchers and clinicians

International Textbook of Obesity

International Textbook of Obesity
Author: Per Björntorp
Publsiher: Wiley-Blackwell
Total Pages: 546
Release: 2001-06-15
ISBN 10: 1928374650XXX
ISBN 13: UOM:39015054441137
Language: EN, FR, DE, ES & NL

International Textbook of Obesity Book Review:

The prevalence of obesity has now reached such proportions that in many parts of the world it is one of the most dominant health problems. Obesity leads to a number of serious diseases such as type 2 diabetes, cardiovascular disease, hypertension, stroke and cancer as well as psychological problems and a poor quality of life. Obesity research is now very active and understanding of the disease has greatly increased. The International Textbook of Obesity offers a definitive coverage of the area looking at epidemiology, causes, current research and management. * Gives an up to date account of the field * Edited by a leading expert in the area * Contributions from an impressive array of authors including many from young researchers giving new perspectives on the issues This will be a lasting reference for a wide range of academic and professional health care workers, including obesity research specialists, diebetologists, nutritionists, practising physicians and endocrinologists.

Pathophysiology of Obesity Induced Health Complications

Pathophysiology of Obesity Induced Health Complications
Author: Paramjit S. Tappia,Bram Ramjiawan,Naranjan S. Dhalla
Publsiher: Springer Nature
Total Pages: 345
Release: 2020-01-17
ISBN 10: 3030353583
ISBN 13: 9783030353582
Language: EN, FR, DE, ES & NL

Pathophysiology of Obesity Induced Health Complications Book Review:

​According to the World Health Organization, the epidemic of global obesity has nearly tripled since 1975. In 2016, more than 1.9 billion adults were overweight, over 650 million of which were obese. Being overweight and obese has been linked to a number of non-communicable, chronic diseases. Pathophysiology of Obesity-Induced Health Complications is a compilation of review articles dedicated to describe co-morbidities associated with obesity. The wide range that is covered is of significant interest to basic research scientists, clinicians and graduate students who are engaged in studying obesity-induced health complications. Furthermore, this book highlights the potential of novel approaches for the prevention and treatment of obesity and its related illnesses. Nineteen articles in this book are organized in four sections that are designed to provide an overview of obesity-induced health complications. The first section serves as an introductory section on the prevalence, causes, consequences, treatments and preventive approaches for obesity. Section two covers the metabolic disturbances and inflammation due to obesity. The third section is focused on neurological and visceral complications as a consequence of obesity. The final section covers strategies for the prevention of obesity-induced complications. The book illustrates that obesity can result in a diverse range of pathophysiological conditions that adversely affect health.

Adiposity

Adiposity
Author: Jan Gordeladze
Publsiher: BoD – Books on Demand
Total Pages: 252
Release: 2017-03-15
ISBN 10: 9535129953
ISBN 13: 9789535129950
Language: EN, FR, DE, ES & NL

Adiposity Book Review:

This book is the first in a series of two, featuring the Adiposity - Epidemiology and Treatment Modalities, serving as a summary of the traditional views on how the organ systems are affected when higher organs start to suffer from enhanced body weight, where most of this additional weight consists of white adipose tissue (WAT). The understanding of the "epidemiology" of obesity will consequently enable clinicians and researchers to better understand the untoward "trends" of "metabolic aberrations" from a well-organized and health-bringing homeostasis, with fully responding WAT and BAT, thus enabling a balance between fat-producing and fat-metabolizing tissues for the benefit of the various organ systems taking care of the fat and carbohydrate metabolism, normally yielding a balanced energy turnover, ensuring "healthy" cell phenotypes, which optimally coordinate the energy metabolism in a well-functioning organism throughout a lifetime.

The Weight of Obesity

The Weight of Obesity
Author: Emily Yates-Doerr
Publsiher: University of California Press
Total Pages: 248
Release: 2015-09-22
ISBN 10: 0520286820
ISBN 13: 9780520286825
Language: EN, FR, DE, ES & NL

The Weight of Obesity Book Review:

A woman with hypertension refuses vegetables. A man with diabetes adds iron-fortified sugar to his coffee. As death rates from heart attacks, strokes, and diabetes in Latin America escalate, global health interventions increasingly emphasize nutrition, exercise, and weight loss—but much goes awry as ideas move from policy boardrooms and clinics into everyday life. Based on years of intensive fieldwork, The Weight of Obesity offers poignant stories of how obesity is lived and experienced by Guatemalans who have recently found their diets—and their bodies—radically transformed. Anthropologist Emily Yates-Doerr challenges the widespread view that health can be measured in calories and pounds, offering an innovative understanding of what it means to be healthy in postcolonial Latin America. Through vivid descriptions of how people reject global standards and embrace fatness as desirable, this book interferes with contemporary biomedicine, adding depth to how we theorize structural violence. It is essential reading for anyone who cares about the politics of healthy eating.

Obesity Epidemiology

Obesity Epidemiology
Author: Frank Hu
Publsiher: Oxford University Press
Total Pages: 512
Release: 2008-03-21
ISBN 10: 9780199718474
ISBN 13: 0199718474
Language: EN, FR, DE, ES & NL

Obesity Epidemiology Book Review:

During the past twenty years there has been a dramatic increase in obesity in the United States. An estimated thirty percent of adults in the US are obese; in 1980, only fifteen percent were. The issue is gaining greater attention with the CDC and with the public health world in general. This book will offer practical information about the methodology of epidemiologic studies of obesity, suitable for graduate students and researchers in epidemiology, and public health practitioners with an interest in the issue. The book will be structured in four main sections, with the majority of chapters authored by Dr. Hu, and some authored by specialists in specific areas. The first section will consider issues surrounding the definition of obesity, measurement techniques, and the designs of epidemiologic studies. The second section will address the consequences of obesity, looking at epidemiologic studies that focus on cardio-vascular disease, diabetes, and cancer The third section will look at determinants obesity, reviewing a wide range of risk factors for obesity including diet, physical activity and sedentary behaviors, sleep disorders, psychosocial factors, physical environment, biochemical and genetic predictors, and intrauterine exposures. In the final section, the author will discuss the analytical issues and challenges for epidemiologic studies of obesity.

Obesity

Obesity
Author: World Health Organization
Publsiher: World Health Organization
Total Pages: 253
Release: 2000
ISBN 10: 9241208945
ISBN 13: 9789241208949
Language: EN, FR, DE, ES & NL

Obesity Book Review:

This report issues a call for urgent action to combat the growing epidemic of obesity, which now affects developing and industrialized countries alike. Adopting a public health approach, the report responds to both the enormity of health problems associated with obesity and the notorious difficulty of treating this complex, multifactorial disease. With these problems in mind, the report aims to help policy-makers introduce strategies for prevention and management that have the greatest chance of success. The importance of prevention as the most sensible strategy in developing countries, where obesity coexists with undernutrition, is repeatedly emphasized. Recommended lines of action, which reflect the consensus reached by 25 leading authorities, are based on a critical review of current scientific knowledge about the causes of obesity in both individuals and populations. While all causes are considered, major attention is given to behavioural and societal changes that have increased the energy density of diets, overwhelmed sophisticated regulatory systems that control appetite and maintain energy balance, and reduced physical activity. Specific topics discussed range from the importance of fat content in the food supply as a cause of population-wide obesity, through misconceptions about obesity held by both the medical profession and the public, to strategies for dealing with the alarming prevalence of obesity in children. The report has eleven chapters presented in five parts. Part one, which assesses the magnitude of the problem, explains the system for classifying overweight and obesity based on the body mass index, considers the importance of fat distribution, and provides an overview of trends in all regions of the world, concluding that obesity is increasing worldwide at an alarming rate. Chapters in part two evaluate the true costs of obesity in terms of physical and mental ill health, and the human and financial resources diverted to deal with these problems. Specific health consequences discussed include increased risk of cardiovascular disease, cancer, and other noncommunicable diseases, endocrine and metabolic disturbances, debilitating health problems, and psychological problems. The health benefits and risks of weight loss are also assessed. Part three draws on the latest research findings to consider specific factors involved in the development of overweight and obesity. Discussion centres on factors, such as high intakes of fat, that may disrupt normal physiological regulation of appetite and energy balance, and the role of dietary factors and levels of physical activity. In terms of opportunities for prevention, particular attention is given to the multitude of environmental and societal forces that adversely affect food intake and physical activity and may thus overwhelm the physiological regulatory systems that keep weight stable in the long term. The possible role of genetic and biological susceptibility is also briefly considered. Against this background, the fourth and most extensive part maps out strategies for prevention and management at both the population and individual levels. Separate chapters address the need to develop population-based strategies that tackle the environmental and societal factors implicated in the development of obesity, and compare the effectiveness of current options for managing overweight or obese individuals. Specific strategies discussed include dietary management, physical activity and exercise programmes, behaviour modification, drug treatment, and gastric surgery. While noting striking recent progress in the development of drug treatments, the report concludes that gastric surgery continues to show the best long-term success in treating the severely obese. The final part sets out key conclusions and recommendations for responding to the global obesity epidemic and identifies priority areas where more research is urgently needed. "... the volume is clearly written, and carries a wealth of summary information that is likely to be invaluable for anyone interested in the public health aspects of obesity and fatness, be they students, practitioner or researcher." - Journal of Biosocial Science

Obesity

Obesity
Author: Tahir Ahmed Mahmood,Sabaratnam Arulkumaran
Publsiher: Newnes
Total Pages: 658
Release: 2013
ISBN 10: 012416045X
ISBN 13: 9780124160453
Language: EN, FR, DE, ES & NL

Obesity Book Review:

Bringing together experts from a variety of specialties to examine the issues and challenges of obesity, this book discusses how obesity affects fertility, reproduction and pregnancy.

The Surgeon General s Vision for a Healthy and Fit Nation

The Surgeon General s Vision for a Healthy and Fit Nation
Author: U. S. Department of Health and Human Services,Office of the Surgeon General
Publsiher: Createspace Independent Pub
Total Pages: 24
Release: 2012-07-23
ISBN 10: 9781478298588
ISBN 13: 1478298588
Language: EN, FR, DE, ES & NL

The Surgeon General s Vision for a Healthy and Fit Nation Book Review:

Our nation stands at a crossroads. Today's epidemic of overweight and obesity threatens the historic progress we have made in increasing American's quality and years of healthy life. Two-third of adults and nearly one in three children are overweight or obese. In addition, many racial and ethnic groups and geographic regions of the United States are disproportionately affected. The sobering impact of these numbers is reflected in the nation's concurrent epidemics of diabetes, heart disease, and other chronic diseases. If we do not reverse these trends, researchers warn that many of our children—our most precious resource—will be seriously afflicted in early adulthood with medical conditions such as diabetes and heart disease. This future is unacceptable. The Surgeon General asks you to join me in combating this crisis. Every one of us has an important role to play in the prevention and control of obesity. Mothers, fathers, teachers, business executives, child care professionals, clinicians, politicians, and government and community leaders—we must all commit to changes that promote the health and wellness of our families and communities. As a nation, we must create neighborhood communities that are focused on healthy nutrition and regular physical activity, where the healthiest choices are accessible for all citizens. Children should be having fun and playing in environments that provide parks, recreational facilities, community centers, and walking and bike paths. Healthy foods should be affordable and accessible. Increased consumer knowledge and awareness about healthy nutrition and physical activity will foster a growing demand for healthy food products and exercise options, dramatically influencing marketing trends. Hospitals, work sites, and communities should make it easy for mothers to initiate and sustain breastfeeding as this practice has been shown to prevent childhood obesity. Working together, we will create an environment that promotes and facilitates healthy choices for all Americans. And we will live longer and healthier lives. In the 2001 Surgeon General's Call to Action to Prevent and Decrease Overweight and Obesity, former Surgeon General David Satcher, MD, PhD, warned us of the negative effects of the increasing weight of our citizens and outlined a public health response to reverse the trend. Although we have made some strides since 2001, the prevalence of obesity, obesity-related diseases, and premature death remains too high. The Surgeon General is calling on all Americans to join in a national grassroots effort to reverse this trend. Plans include showing people how to choose nutritious food, add more physical activity to their daily lives, and manage the stress that so often derails their best efforts at developing healthy habits. The real goal is not just a number on a scale, but optimal health for all Americans at every stage of life. To achieve this goal, we must all work together to share resources, educate our citizens, and partner with business and government leaders to find creative solutions in our neighborhoods, towns, and cities from coast to coast. Together, we can become a nation committed to become healthy and fit.

The Challenge of Obesity in the WHO European Region and the Strategies for Response

The Challenge of Obesity in the WHO European Region and the Strategies for Response
Author: World Health Organization. Regional Office for Europe
Publsiher: World Health Organization
Total Pages: 60
Release: 2007
ISBN 10: 9289013885
ISBN 13: 9789289013888
Language: EN, FR, DE, ES & NL

The Challenge of Obesity in the WHO European Region and the Strategies for Response Book Review:

In a brief, clear and easily accessible way, this summary illustrates the dynamics of the obesity epidemic and its impact on public health throughout the WHO European Region, particularly in eastern countries. It describes how factors that increase the risk of obesity are shaped in different settings, such as the family, school, community and workplace. It makes both ethical and economic arguments for accelerating action against obesity, and analyses effective programs and policies in different government sectors, such as education, health, agriculture and trade, urban planning and transport. The summary also describes how to design policies and programs to prevent obesity and how to monitor progress, and calls for specific action by stakeholders: not only government sectors but also the private sector - including food manufacturers, advertisers and traders - and professional consumers' and international and intergovernmental organizations such as the European Union.

The Future of the Public s Health in the 21st Century

The Future of the Public s Health in the 21st Century
Author: Institute of Medicine,Board on Health Promotion and Disease Prevention,Committee on Assuring the Health of the Public in the 21st Century
Publsiher: National Academies Press
Total Pages: 536
Release: 2003-02-01
ISBN 10: 0309133181
ISBN 13: 9780309133180
Language: EN, FR, DE, ES & NL

The Future of the Public s Health in the 21st Century Book Review:

The anthrax incidents following the 9/11 terrorist attacks put the spotlight on the nation's public health agencies, placing it under an unprecedented scrutiny that added new dimensions to the complex issues considered in this report. The Future of the Public's Health in the 21st Century reaffirms the vision of Healthy People 2010, and outlines a systems approach to assuring the nation's health in practice, research, and policy. This approach focuses on joining the unique resources and perspectives of diverse sectors and entities and challenges these groups to work in a concerted, strategic way to promote and protect the public's health. Focusing on diverse partnerships as the framework for public health, the book discusses: The need for a shift from an individual to a population-based approach in practice, research, policy, and community engagement. The status of the governmental public health infrastructure and what needs to be improved, including its interface with the health care delivery system. The roles nongovernment actors, such as academia, business, local communities and the media can play in creating a healthy nation. Providing an accessible analysis, this book will be important to public health policy-makers and practitioners, business and community leaders, health advocates, educators and journalists.

Comparative Quantification of Health Risks Sexual and reproductive health

Comparative Quantification of Health Risks  Sexual and reproductive health
Author: Majid Ezzati
Publsiher: World Health Organization
Total Pages: 2248
Release: 2004
ISBN 10: 9241580313
ISBN 13: 9789241580311
Language: EN, FR, DE, ES & NL

Comparative Quantification of Health Risks Sexual and reproductive health Book Review:

Accompanying CD-ROM contains annex tables detailing population attributable fractions, mortality, and disease burden for selected major risk factors.

Handbook of Research on Geriatric Health Treatment and Care

Handbook of Research on Geriatric Health  Treatment  and Care
Author: Prasad, Barre Vijaya,Akbar, Shamsi
Publsiher: IGI Global
Total Pages: 604
Release: 2018-03-30
ISBN 10: 1522534814
ISBN 13: 9781522534815
Language: EN, FR, DE, ES & NL

Handbook of Research on Geriatric Health Treatment and Care Book Review:

Mental and physical disorders are common in old age but frequently remain undetected and untreated. Managing treatment and controlling symptoms of these disorders is imperative to the longevity and quality of life of patients. The Handbook of Research on Geriatric Health, Treatment, and Care provides emerging research on promoting health in older adults by preventing and treating diseases and disabilities. By highlighting topics such as alternative treatment, clinical diagnosis, and positive psychology, this publication explores the methods and approaches of identifying and diagnosing epidemiological factors that contribute to geriatric health issues. This book is an important resource for healthcare professionals, academicians, medical practitioners, researchers, and students seeking current research on the methods and strategies for maintaining healthy and successful care for the elderly.

The Practical Guide

The Practical Guide
Author: Anonim
Publsiher: Unknown
Total Pages: 80
Release: 2002
ISBN 10: 1928374650XXX
ISBN 13: MINN:31951P00598699P
Language: EN, FR, DE, ES & NL

The Practical Guide Book Review:

Cellular and Biochemical Mechanisms of Obesity

Cellular and Biochemical Mechanisms of Obesity
Author: Paramjit S. Tappia,Bram Ramjiawan,Naranjan S. Dhalla
Publsiher: Springer Nature
Total Pages: 414
Release: 2021-12-15
ISBN 10: 3030847632
ISBN 13: 9783030847630
Language: EN, FR, DE, ES & NL

Cellular and Biochemical Mechanisms of Obesity Book Review:

Global health has been challenged with the dawning of the era of the obesity epidemic, and thus as a consequence, strategies to reduce obesity have become public health priorities. According to the United Nations, obesity has been identified as a concern for achieving Sustainable Development Goals. Obesity is a serious health problem with an increased risk of several common diseases including diabetes, cardiovascular disease, and cancer. Although the fundamental cause of obesity and overweight is an imbalance between calorie intake and calorie expenditure, the underlying biochemical and metabolic processes that cause obesity are not fully understood. Two earlier volumes dedicated to the subject of obesity, published in the series “Advances in Biochemistry in Health and Disease” focused on the pathophysiology of obesity-induced health complications and the biochemistry of cardiovascular dysfunction in obesity. This book brings together contributions from international experts in the field to describe advancements on the mechanisms leading to development of obesity and related complications. There are 21 chapters in two different parts in this book, comprising of Part I: Pathophysiologic Mechanisms of Obesity (11 chapters) and Part II: Therapeutic Mechanisms of Obesity (10 chapters). This book will serve as a resource and be of interest to health professionals, medical students, fellows, residents and graduate students. It will also evoke innovative research and effective approaches for the prevention of obesity. This volume will accentuate that obesity is a major health hazard in its own right and that appropriate public health measures should be implemented to prevent or reduce or even reverse the impact of this global chronic disease.

Diet Nutrition and the Prevention of Chronic Diseases

Diet  Nutrition  and the Prevention of Chronic Diseases
Author: World Health Organization
Publsiher: World Health Organization
Total Pages: 149
Release: 2003-04-22
ISBN 10: 924120916X
ISBN 13: 9789241209168
Language: EN, FR, DE, ES & NL

Diet Nutrition and the Prevention of Chronic Diseases Book Review:

Trends such as shifting dietary patterns and an increasingly sedentary lifestyle combined with smoking and alcohol consumption are major risk factors for noncommunicable chronic diseases such as obesity, diabetes, cardiovascular diseases such as hypertension and stroke, cancer dental diseases and osteoporosis. This report reviews the scientific evidence on the effects of diet, nutrition and physical activity on chronic diseases and makes recommendations for public health policies and programmes. Issues considered include the macro-economic implications of public health on agriculture and the global supply and demand for fresh and processed foods.

Weighing the Options

Weighing the Options
Author: Institute of Medicine,Committee to Develop Criteria for Evaluating the Outcomes of Approaches to Prevent and Treat Obesity
Publsiher: National Academies Press
Total Pages: 296
Release: 1995-03-01
ISBN 10: 9780309132572
ISBN 13: 0309132576
Language: EN, FR, DE, ES & NL

Weighing the Options Book Review:

Nearly one out of every three adults in America is obese and tens of millions of people in the United States are dieting at any one time. This has resulted in a weight-loss industry worth billions of dollars a year and growing. What are the long-term results of weight-loss programs? How can people sort through the many programs available and select one that is right for them? Weighing the Options strives to answer these questions. Despite widespread public concern about weight, few studies have examined the long-term results of weight-loss programs. One reason that evaluating obesity management is difficult is that no other treatment depends so much on an individual's own initiative and state of mind. Now, a distinguished group of experts assembled by the Institute of Medicine addresses this compelling issue. Weighing the Options presents criteria for evaluating treatment programs for obesity and explores what these criteria mean--to health care providers, program designers, researchers, and even overweight people seeking help. In presenting its criteria the authors offer a wealth of information about weight loss: how obesity is on the rise, what types of weight-loss programs are available, how to define obesity, how well we maintain weight loss, and what approaches and practices appear to be most successful. Information about weight-loss programs--their clients, staff qualifications, services, and success rates--necessary to make wise program choices is discussed in detail. The book examines how client demographics and characteristics--including health status, knowledge of weight-loss issues, and attitude toward weight and body image--affect which programs clients choose, how successful they are likely to be with their choices, and what this means for outcome measurement. Short- and long-term safety consequences of weight loss are discussed as well as clinical assessment of individual patients. The authors document the health risks of being overweight, summarizing data indicating that even a small weight loss reduces the risk of disease and depression and increases self-esteem. At the same time, weight loss has been associated with some poor outcomes, and the book discusses the implications for program evaluation. Prevention can be even more important than treatment. In Weighing the Options, programs for population groups, efforts targeted to specific groups at high risk for obesity, and prevention of further weight gain in obese individuals get special attention. This book provides detailed guidance on how the weight-loss industry can improve its programs to help people be more successful at long-term weight loss. And it provides consumers with tips on selecting a program that will improve their chances of permanently losing excess weight.

The Challenge of Treating Obesity and Overweight

The Challenge of Treating Obesity and Overweight
Author: National Academies of Sciences, Engineering, and Medicine,Health and Medicine Division,Food and Nutrition Board,Roundtable on Obesity Solutions
Publsiher: National Academies Press
Total Pages: 116
Release: 2018-01-21
ISBN 10: 030946370X
ISBN 13: 9780309463706
Language: EN, FR, DE, ES & NL

The Challenge of Treating Obesity and Overweight Book Review:

The Roundtable on Obesity Solutions of the National Academies of Sciences, Engineering, and Medicine held a workshop in Washington, DC, on April 6, 2017, titled The Challenge of Treating Obesity and Overweight: A Workshop. The discussions covered treatments for obesity, overweight, and severe obesity in adults and children; emerging treatment opportunities; the development of a workforce for obesity treatments; payment and policy considerations; and promising paths to move forward. This publication summarizes the presentations and discussions from the workshop.

Disease Control Priorities Third Edition Volume 5

Disease Control Priorities  Third Edition  Volume 5
Author: Dorairaj Prabhakaran,Shuchi Anand,Thomas A. Gaziano,Jean-Claude Mbanya,Rachel Nugent
Publsiher: World Bank Publications
Total Pages: 466
Release: 2017-11-17
ISBN 10: 1464805202
ISBN 13: 9781464805202
Language: EN, FR, DE, ES & NL

Disease Control Priorities Third Edition Volume 5 Book Review:

Cardiovascular, respiratory, and related conditions cause more than 40 percent of all deaths globally, and their substantial burden is rising, particularly in low- and middle-income countries (LMICs). Their burden extends well beyond health effects to include significant economic and societal consequences. Most of these conditions are related, share risk factors, and have common control measures at the clinical, population, and policy levels. Lives can be extended and improved when these diseases are prevented, detected, and managed. This volume summarizes current knowledge and presents evidence-based interventions that are effective, cost-effective, and scalable in LMICs.

The Epigenome and Developmental Origins of Health and Disease

The Epigenome and Developmental Origins of Health and Disease
Author: Cheryl S Rosenfeld
Publsiher: Academic Press
Total Pages: 560
Release: 2015-10-10
ISBN 10: 0128016728
ISBN 13: 9780128016725
Language: EN, FR, DE, ES & NL

The Epigenome and Developmental Origins of Health and Disease Book Review:

The Epigenome and Developmental Origins of Health and Disease synthesizes the existing knowledge on how the in utero environment could be the most important environment in shaping later risk for various diseases or to conversely promote the health of the offspring. The book mines the existing literature from a variety of disciplines from toxicology to nutrition to epigenetics to reveal how contrasting maternal in utero environmental changes might be leading to epigenetic convergence and the resulting deleterious phenotypic and physiological effects in our offspring. It is increasingly becoming apparent that even subtle changes in the mother’s diet, stress, and exposure to low concentrations of toxic chemicals at levels deemed safe by the EPA and FDA, such as endocrine disrupting compounds (EDC), can dramatically impact the health of our children, possibly leading to metabolic, cardiovascular, immunological, neurobehavioral disorders, and increased risk for cancer to list but a few examples. Informs how everyday choices pregnant women make can impact child development Ties together how in utero environmental changes may be inducing epigenetic changes in the offspring leading to overlapping phenotypes regardless of the initial insult (toxic, nutrition, or stress) Includes a boxed-in area in each chapter for further references and resources to keep up with the field Features video interviews with the authors and other key leaders in the field