Fractal Analysis of the Binding and Dissociation Kinetics for Different Analytes on Biosensor Surfaces

Fractal Analysis of the Binding and Dissociation Kinetics for Different Analytes on Biosensor Surfaces
Author: Ajit Sadana,Neeti Sadana
Publsiher: Elsevier
Total Pages: 372
Release: 2007-12-20
ISBN 10: 9780080555010
ISBN 13: 0080555012
Language: EN, FR, DE, ES & NL

Fractal Analysis of the Binding and Dissociation Kinetics for Different Analytes on Biosensor Surfaces Book Review:

Biosensors are finding increasing applications in different areas. Over the last few years the areas where biosensors may be used effectively has increased dramatically. This book like the previous four books on analyte-receptor binding and dissociation kinetics by this author addresses the often neglected area. The kinetics of binding and dissociation in solution to appropriate receptors immobilized on biosensor surfaces occurs under diffusional limitations on structured surfaces. The receptors immobilized on the biosensor surface contribute to the degree of heterogeneity on the sensor chip surface. The fractal analysis examples presented throughout the book provide a convenient means to make quantitative the degree of heterogeneity present on the sensor surface, and relates it to the binding and dissociation rate coefficients. The fractal dimension is a quantitative measure of the degree of heterogeneity present on the biosensor surface. The book emphasizes medially-oriented examples. The detection of disease-related analytes is also emphasized. The intent being that if intractable and insidious diseases are detected earlier, they will be controlled better, eventually leading to a better prognosis. Chapter 3 is a new chapter that emphasizes enhancing the relevant biosensor performance parameters such as sensitivity, stability, selectivity, response time, etc. As usual, as done in previous books by this author, the last chapter provides an update of the economics involved in biosensors, and the difficulties encounters in starting-up a biosensor company. - Modelling of binding and dissociation kinetics of analyte-receptor reactions on biosensor surfaces: provides physical insights into these reactions occurring on biosensor surfaces. Very few researchers even attempt to analyze the kinetics of these types of reactions. - Fractal analysis used to model the binding and dissociation kinetics: original and unique approach. - Economic analysis provided in the last chapter: helps balance the book; besides providing much-needed information not available in the open literature. - Emphasis on improving biosensor performance parameters: helps make biosensors better. - Empahsis on medically-related analytes: helps in prognosis of diseases.

Binding and Dissociation Kinetics for Different Biosensor Applications Using Fractals

Binding and Dissociation Kinetics for Different Biosensor Applications Using Fractals
Author: Ajit Sadana
Publsiher: Elsevier
Total Pages: 384
Release: 2006-08-08
ISBN 10: 9780080463698
ISBN 13: 008046369X
Language: EN, FR, DE, ES & NL

Binding and Dissociation Kinetics for Different Biosensor Applications Using Fractals Book Review:

The application of biosensors is expanding in different areas. These are portable and convenient devices that permit the rapid, accurate, and reliable detection of analytes of interest present either in the atmosphere or in aqueous or in liquid phases. The detection of glucose levels in blood for the effective management of diabetes is one. Though different biosensors have been designed for an increasing number of applications, the kinetics of binding (and dissociation) of analytes by the receptors on the biosensor surfaces has not been given enough attention in the open literature. This is a very important area of investigation since it significantly impacts biosensor performance parameters such as stability, sensitivity, selectivity, response time, regenerability, etc. Binding and Dissociation Kinetics for Different Biosensor Applications Using Fractals addresses this critical need besides helping to correct or demonstrate the need to modify the present software available with commercial biosensors that determines the kinetics of analyte-receptor reactions on biosensor surfaces. * first book to provide detailed kinetic analysis of the binding and dissociation reactions that are occuring on the biosensor surface * addresses the area of analyte-receptor binding and dissociation kinetics occurring on biosensor surfaces * provides physical insights into reactions occuring on biosensor surfaces

Biosensors Kinetics of Binding and Dissociation Using Fractals

Biosensors  Kinetics of Binding and Dissociation Using Fractals
Author: Ajit Sadana
Publsiher: Elsevier
Total Pages: 401
Release: 2003-12-31
ISBN 10: 9780444515124
ISBN 13: 0444515127
Language: EN, FR, DE, ES & NL

Biosensors Kinetics of Binding and Dissociation Using Fractals Book Review:

Effect of Reynolds number on fractal binding kinetics on a surface-based biosensor -- DNA fractal binding and dissociation kinetics -- Fractal analysis of binding and dissociation interactions of estrogen receptors to ligands on biosensor surfaces -- A fractal analysis of analyte-estrogen receptor binding and dissociation kinetics using biosensors : environmental effects -- A fractal analysis of analyte-estrogen receptor binding and dissociation kinetics using biosensors : biomedical effects -- Fractal analysis of binding interactions of nuclear estrogen receptors occurring on biosensor surfaces -- A kinetic study of analyte-receptor binding and dissociation for biosensor applications : a fractal analysis for cholera toxin and peptide-protein interactions / -- The temporal nature of the binding and dissociation rate coefficients and the affinity values for biosensor kinetics -- Fractal analysis of analyte-receptor binding and dissociation, and dissociation alone for biosensor applicati ...

A Fractal Analysis of Binding and Dissociation Kinetics for Analytes Related to Various Human Diseases on Biosensor Surfaces

A Fractal Analysis of Binding and Dissociation Kinetics for Analytes Related to Various Human Diseases on Biosensor Surfaces
Author: Atul M. Doke
Publsiher: Unknown
Total Pages: 228
Release: 2006
ISBN 10: 1928374650XXX
ISBN 13: OCLC:82144106
Language: EN, FR, DE, ES & NL

A Fractal Analysis of Binding and Dissociation Kinetics for Analytes Related to Various Human Diseases on Biosensor Surfaces Book Review:

A Fractal Analysis of Chemical Kinetics with Applications to Biological and Biosensor Interfaces

A Fractal Analysis of Chemical Kinetics with Applications to Biological and Biosensor Interfaces
Author: Ajit Sadana,Neeti Sadana,Richa Sadana
Publsiher: Elsevier
Total Pages: 337
Release: 2018-07-31
ISBN 10: 0444638822
ISBN 13: 9780444638823
Language: EN, FR, DE, ES & NL

A Fractal Analysis of Chemical Kinetics with Applications to Biological and Biosensor Interfaces Book Review:

A Fractal Analysis of Chemical Kinetics with Applications to Biological and Biosensor Interfaces analyzes the kinetics of binding and dissociation of different analytes by different biosensor techniques, demonstrating and then comparing each. Emphasis is placed on newer instrumentation techniques, such as SPRi (surface plasmon resonance imaging), and classical techniques, such as SPR (surface plasmon resonance), and finally, DNA biosensors and nanobiosensors. In addition, a final capstone chapter includes biosensor economics. These topics are all covered in one comprehensive book in a way that cannot be found elsewhere. Analyzes the kinetics of binding on biosensor surfaces Presents and compares different biosensor techniques Provides insights into the binding and dissociation mechanisms of analytes on biosensor surfaces Links the heterogeneity of biosensor surfaces to dissociation rate coefficients

Fractal Binding and Dissociation Kinetics for Different Biosensor Applications

Fractal Binding and Dissociation Kinetics for Different Biosensor Applications
Author: Ajit Sadana
Publsiher: Elsevier
Total Pages: 650
Release: 2005-07-06
ISBN 10: 9780080458915
ISBN 13: 0080458912
Language: EN, FR, DE, ES & NL

Fractal Binding and Dissociation Kinetics for Different Biosensor Applications Book Review:

Biosensors are portable and convenient devices that permit the rapid and reliable analysis of substances. They are increasingly used in healthcare, drug design, environmental monitoring and the detection of biological, chemical, and toxic agents. Fractal Binding and Dissociation Kinetics for Different Biosensor Applications focuses on two areas of expanding biosensor development that include (a) the detection of biological and chemical pathogens in the atmosphere, and (b) biomedical applications, especially in healthcare. The author provides numerous examples of practical uses, particularly biomedical applications and the detection of biological or chemical pathogens. This book also contains valuable information dedicated to the economics of biosensors. After reading this book, the reader will gain invaluable insight into how biosensors work and how they may be used more effectively. * No other book provides a detailed kinetic analysis of the binding and dissociation reactions occurring on the biosensor surfaces * Packed with examples of practical uses of biosensors * Includes chapters dedicated to the economics of biosensors

A Fractal Analysis of the Binding and Dissociation Kinetics of Analyte receptor Systems on Biosensor Surfaces

A Fractal Analysis of the Binding and Dissociation Kinetics of Analyte receptor Systems on Biosensor Surfaces
Author: Ifejesu Eni-olorunda
Publsiher: Unknown
Total Pages: 186
Release: 2010
ISBN 10: 1928374650XXX
ISBN 13: OCLC:692197300
Language: EN, FR, DE, ES & NL

A Fractal Analysis of the Binding and Dissociation Kinetics of Analyte receptor Systems on Biosensor Surfaces Book Review:

Abstract: The ability to detect and accurately measure the concentration of certain substances or species is useful in monitoring the activity of substances which may be harmful when present beyond a certain threshold usually in analyte-receptor systems. Biosensors are analytical devices which are capable of detecting the presence of target species in such systems, typically, in small concentrations. Some fields of application where this is highly relevant include drug detection in pharmacology, toxic chemical detection, food industry, biotechnology, and the healthcare field. Most of these sensing devices are commercially available and possess certain characteristics responsible for their operation efficiency. Several kinetic theories have been postulated in an attempt to describe the nature of interactions that occur on biosensor surfaces and also predict kinetic parameters associated with these interactions. The fractal kinetic theory provides novel physical insight into the kinetics of analyte-receptor reactions occurring on biosensor surfaces. It has been used in analyses presented in this thesis to evaluate important kinetic parameters such as the binding and dissociation rate coefficients, fractal dimensions and affinity values. Examples are presented on modern improvements to biosensor technology with special attention to applications within the bio-medical field and certain protein-protein reactions in the human body. Knowledge of these parameters in science can be instrumental in implementing biosensor design modifications that can improve key performance characteristics such as stability, specificity/selectivity, and response time.

Handbook of Biosensors and Biosensor Kinetics

Handbook of Biosensors and Biosensor Kinetics
Author: Ajit Sadana,Neeti Sadana
Publsiher: Elsevier
Total Pages: 536
Release: 2010-08-26
ISBN 10: 9780080932859
ISBN 13: 0080932851
Language: EN, FR, DE, ES & NL

Handbook of Biosensors and Biosensor Kinetics Book Review:

Biosensors are essential to an ever-expanding range of applications, including healthcare; drug design; detection of biological, chemical, and toxic agents; environmental monitoring; biotechnology; aviation; physics; oceanography; and the protection of civilian and engineering infrastructures. This book, like the previous five books on biosensors by this author (and one by the co-author), addresses the neglected areas of analyte-receptor binding and dissociation kinetics occurring on biosensor surfaces. Topics are covered in a comprehensive fashion, with homogeneous presentation for the benefit of the reader. The contributors address the economic aspects of biosensors and incorporate coverage of biosensor fabrication and nanobiosensors, among other topics. The comments, comparison, and discussion presented provides a better perspective of where the field of biosensors is heading. Serves as a comprehensive resource on biosensor analysis Examines timely topics such as biosensor fabrication and nanobiosensors Covers economic aspects and medical applications (e.g., the role of analytes in controlling diabetes)

Biomarkers and Biosensors

Biomarkers and Biosensors
Author: Ajit Sadana,Neeti Sadana
Publsiher: Newnes
Total Pages: 702
Release: 2014-12-08
ISBN 10: 0444537953
ISBN 13: 9780444537959
Language: EN, FR, DE, ES & NL

Biomarkers and Biosensors Book Review:

Biomarkers and Biosensors offers thorough coverage of biomarker/biosensor interaction, current research trends, and future developments in applications of drug discovery. This book is useful to researchers in this field as well as clinicians interested in new developments in early detection and diagnosis of disease or the mode of operation of biomarkers. Biomarkers and Biosensors also emphasizes kinetics, and clearly delineates how this influences the biomarker market. Offers thorough coverage of the kinetics of biomarker interaction with the biosensor surface Provides evidence-based approach to evaluate effectiveness Provides pharmaceutical chemists the possibilities and methodology in assessing the effectiveness of new drugs Provides the information needed for the selection of the best biomarker for a specific application

Encyclopedia of Surface and Colloid Science

Encyclopedia of Surface and Colloid Science
Author: P. Somasundaran
Publsiher: CRC Press
Total Pages: 6675
Release: 2006
ISBN 10: 9780849396076
ISBN 13: 0849396077
Language: EN, FR, DE, ES & NL

Encyclopedia of Surface and Colloid Science Book Review:

Dekker Encyclopedia of Nanoscience and Nanotechnology

Dekker Encyclopedia of Nanoscience and Nanotechnology
Author: James A. Schwarz,Cristian I. Contescu,Karol Putyera
Publsiher: CRC Press
Total Pages: 4014
Release: 2004
ISBN 10: 9780824750480
ISBN 13: 0824750489
Language: EN, FR, DE, ES & NL

Dekker Encyclopedia of Nanoscience and Nanotechnology Book Review:

Engineering Biosensors

Engineering Biosensors
Author: Ajit Sadana
Publsiher: Academic Press
Total Pages: 404
Release: 2001-10-04
ISBN 10: 0080523633
ISBN 13: 9780080523637
Language: EN, FR, DE, ES & NL

Engineering Biosensors Book Review:

Biosensors are becoming increasingly important bioanalytical tools in the pharmaceutical, biotechnology, food, and other consumer oriented industries. The technology, though well developed in Europe, is slowly developing and has begun to generate interest in the United States only over the past couple of years. Research is now being directed toward the development of biosensors that are versatile, economical, and simple to use. Engineering Biosensors is a comprehensive introduction to biosensors that includes numerous illustrations to further explain the main concepts and practical examples from existing literature. It describes what biosensors are, where they are used, and how their performance is affected by existing surface characteristics. A better understanding of biosensors, as provided by this book, will greatly assist in the design of new as well as the improvement of existing biosensors. Readers are also provided with invaluable and hard-to-find data on the economics of the biosensor market to assist them in better understanding the market and where it is heading.

Statistical Bioinformatics with R

Statistical Bioinformatics with R
Author: Sunil K. Mathur
Publsiher: Academic Press
Total Pages: 336
Release: 2009-12-21
ISBN 10: 9780123751058
ISBN 13: 0123751055
Language: EN, FR, DE, ES & NL

Statistical Bioinformatics with R Book Review:

Statistical Bioinformatics provides a balanced treatment of statistical theory in the context of bioinformatics applications. Designed for a one or two semester senior undergraduate or graduate bioinformatics course, the text takes a broad view of the subject – not just gene expression and sequence analysis, but a careful balance of statistical theory in the context of bioinformatics applications. The inclusion of R & SAS code as well as the development of advanced methodology such as Bayesian and Markov models provides students with the important foundation needed to conduct bioinformatics. Integrates biological, statistical and computational concepts Inclusion of R & SAS code Provides coverage of complex statistical methods in context with applications in bioinformatics Exercises and examples aid teaching and learning presented at the right level Bayesian methods and the modern multiple testing principles in one convenient book

Methods for Affinity Based Separations of Enzymes and Proteins

Methods for Affinity Based Separations of Enzymes and Proteins
Author: Munishwar N. Gupta
Publsiher: Springer Science & Business Media
Total Pages: 225
Release: 2002-04-01
ISBN 10: 9783764363055
ISBN 13: 3764363053
Language: EN, FR, DE, ES & NL

Methods for Affinity Based Separations of Enzymes and Proteins Book Review:

One major concern of biotechnology is either using enzymes or producing them. Enzyme/protein production is therefore an important starting point for biotechnology. Bioseparation or Downstream Processing constitutes about 40-90% of the total production cost. Driven by economics, highly selective technologies applicable to large-scale processing have emerged during the last decade. These technologies are slowly diffusing to enzymologists who are working on a smaller scale, looking for fast and efficient purification protocols. The affinity-based techniques (including precipitation, two-phase extractions, expanded bed chromatography, perfusion chromatography and monoliths) described in this volume provide current and new cutting-edge methods. Consequently, the book is of main interest to researchers in biochemistry, biochemical engineering and biotechnology, working either in academic or industrial sectors.

Recognition Receptors in Biosensors

Recognition Receptors in Biosensors
Author: Mohammed Zourob
Publsiher: Springer Science & Business Media
Total Pages: 863
Release: 2010-01-08
ISBN 10: 1441909192
ISBN 13: 9781441909190
Language: EN, FR, DE, ES & NL

Recognition Receptors in Biosensors Book Review:

Recognition receptors play a key role in the successful implementation of chemical and biosensors. Molecular recognition refers to non-covalent speci?c binding between molecules, one of which is typically a macromolecule or a molecular assembly, and the other is the target molecule (ligand or analyte). Biomolecular recognition is typically driven by many weak interactions such as hydrogen bo- ing, metal coordination, hydrophobic forces, van der Waals forces, pi-pi interactions and electrostatic interaction (due to permanent charges, dipoles, and quadrupoles) the polarization of charge distributions by the interaction partner leading to ind- tion and dispersion forces, and Pauli-exclusion-principle-derived inter-atomic repulsion, and a strong, “attractive” force arising largely from the entropy of the solvent and termed the hydrophobic effect. In recent years, there has been much progress in understanding the forces that drive the formation of such complexes, and how these forces are relate to the physical properties of the interacting molecules and their environment allows rational design of molecules and materials that interact in speci?c and desired ways. This book presents a signi?cant and up-to-date review of the various recognition elements, their immobilization, characterization techniques by a panel of dist- guished scientists. This work is a comprehensive approach to the recognition receptors area presenting a thorough knowledge of the subject and an effective integration of these receptors on sensor surfaces in order to appropriately convey the state-of the-art fundamentals and applications of the most innovative approaches.

Sensor Systems for Biological Agent Attacks

Sensor Systems for Biological Agent Attacks
Author: National Research Council,Division on Engineering and Physical Sciences,Board on Manufacturing and Engineering Design,Committee on Materials and Manufacturing Processes for Advanced Sensors
Publsiher: National Academies Press
Total Pages: 208
Release: 2005-12-11
ISBN 10: 030909576X
ISBN 13: 9780309095761
Language: EN, FR, DE, ES & NL

Sensor Systems for Biological Agent Attacks Book Review:

Over the last ten years, there has been growing concern about potential biological attacks on the nation’s population and its military facilities. It is now possible to detect such attacks quickly enough to permit treatment of potential victims prior to the onset of symptoms. The capability to “detect to warnâ€, that is in time to take action to minimize human exposure, however, is still lacking. To help achieve such a capability, the Defense Threat Reduction Agency (DTRA) asked the National Research Council (NRC) to assess the development path for “detect to warn†sensors systems. This report presents the results of this assessment including analysis of scenarios for protecting facilities, sensor requirements, and detection technologies and systems. Findings and recommendations are provided for the most probable path to achieve a detect-to-warn capability and potential technological breakthroughs that could accelerate its attainment.

Disposable Electrochemical Sensors for Healthcare Monitoring

Disposable Electrochemical Sensors for Healthcare Monitoring
Author: A Pandikumar,K S Shalini Devi
Publsiher: Royal Society of Chemistry
Total Pages: 448
Release: 2021-04-29
ISBN 10: 1839163372
ISBN 13: 9781839163371
Language: EN, FR, DE, ES & NL

Disposable Electrochemical Sensors for Healthcare Monitoring Book Review:

Disposable electrodes have been widely used as a sensing platform in electrical and electrochemical sensors owing to the possibility of quantitative detection using clinical biomarkers with high precision, sensitivity and reproducibility, which are necessary for accurate diagnosis of the health condition of an individual. This book focusses on the emerging disposable electrochemical sensors in the health sector and the advancement of analytical devices to monitor diabetic, cancer and cardiovascular patients using different nanomaterials. It discusses the upcoming strategies, advantages and the limitations of the existing devices using disposable electrodes. Uniquely, it covers in-depth knowledge of mechanistic features of various designs of screen-printing electrodes and the material aspects required of sensors developed for the healthcare field. It also looks at the portable devices using a variety of materials and the future directions for research in this area. Appealing to the health care industry, this book is aimed at academic and research institutes at both the graduate and postgraduate level. The contributors are leading experts in the field and they are providing guidance for the next decade of research in the field of disposable electrochemical biosensors.

Application of Thermodynamics to Biological and Materials Science

Application of Thermodynamics to Biological and Materials Science
Author: Mizutani Tadashi
Publsiher: BoD – Books on Demand
Total Pages: 642
Release: 2011-01-14
ISBN 10: 9533079800
ISBN 13: 9789533079806
Language: EN, FR, DE, ES & NL

Application of Thermodynamics to Biological and Materials Science Book Review:

Progress of thermodynamics has been stimulated by the findings of a variety of fields of science and technology. The principles of thermodynamics are so general that the application is widespread to such fields as solid state physics, chemistry, biology, astronomical science, materials science, and chemical engineering. The contents of this book should be of help to many scientists and engineers.

Surfaces and Interfaces for Biomaterials

Surfaces and Interfaces for Biomaterials
Author: Pankaj Vadgama
Publsiher: CRC Press
Total Pages: 802
Release: 2005-06-14
ISBN 10: 9780849334467
ISBN 13: 0849334462
Language: EN, FR, DE, ES & NL

Surfaces and Interfaces for Biomaterials Book Review:

Given such problems as rejection, the interface between an implant and its human host is a critical area in biomaterials. Surfaces and Interfaces for Biomaterials summarizes the wealth of research on understanding the surface properties of biomaterials and the way they interact with human tissue. The first part of the book reviews the way biomaterial surfaces form. Part Two then discusses ways of monitoring and characterizing surface structure and behavior. The final two parts of the book look at a range of in vitro and in vivo studies of the complex interactions between biomaterials and the body. Chapters cover such topics as bone and tissue regeneration, the role of interface interactions in biodegradable biomaterials, microbial biofilm formation, vascular tissue engineering and ways of modifying biomaterial surfaces to improve biocompatibility. Surfaces and Interfaces for Biomaterials will be a standard work on how to understand and control surface processes in ensuring biomaterials are used successfully in medicine.

International Journal of Bioinformatics Research and Applications

International Journal of Bioinformatics Research and Applications
Author: Anonim
Publsiher: Unknown
Total Pages: 135
Release: 2006
ISBN 10: 1928374650XXX
ISBN 13: UOM:39015065058375
Language: EN, FR, DE, ES & NL

International Journal of Bioinformatics Research and Applications Book Review: